

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of endogenous antigen (GO:0019883) | 9.99425250 |
| 2 | intra-S DNA damage checkpoint (GO:0031573) | 7.52352957 |
| 3 | dopamine transport (GO:0015872) | 6.04901561 |
| 4 | heart trabecula morphogenesis (GO:0061384) | 5.93360421 |
| 5 | viral transcription (GO:0019083) | 5.79781007 |
| 6 | mRNA splice site selection (GO:0006376) | 5.56270721 |
| 7 | translational termination (GO:0006415) | 5.54094463 |
| 8 | translational elongation (GO:0006414) | 4.94244321 |
| 9 | transmission of nerve impulse (GO:0019226) | 4.87941127 |
| 10 | DNA integration (GO:0015074) | 4.86774017 |
| 11 | nonmotile primary cilium assembly (GO:0035058) | 4.82733166 |
| 12 | ribosomal small subunit assembly (GO:0000028) | 4.81259816 |
| 13 | DNA replication checkpoint (GO:0000076) | 4.76799482 |
| 14 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.70188935 |
| 15 | skeletal muscle tissue regeneration (GO:0043403) | 4.68987023 |
| 16 | trabecula morphogenesis (GO:0061383) | 4.60117509 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 4.59913191 |
| 18 | protein targeting to ER (GO:0045047) | 4.54337895 |
| 19 | protein localization to endoplasmic reticulum (GO:0070972) | 4.38678269 |
| 20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.34540680 |
| 21 | cellular protein complex disassembly (GO:0043624) | 4.18736237 |
| 22 | ribosomal small subunit biogenesis (GO:0042274) | 4.09020026 |
| 23 | viral life cycle (GO:0019058) | 4.08236397 |
| 24 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.97331943 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.91426874 |
| 26 | positive regulation of protein kinase C signaling (GO:0090037) | 3.89067655 |
| 27 | branched-chain amino acid catabolic process (GO:0009083) | 3.86588942 |
| 28 | positive regulation of fatty acid transport (GO:2000193) | 3.84930308 |
| 29 | catecholamine transport (GO:0051937) | 3.80000490 |
| 30 | behavioral response to nicotine (GO:0035095) | 3.75721425 |
| 31 | positive regulation of icosanoid secretion (GO:0032305) | 3.63414130 |
| 32 | translational initiation (GO:0006413) | 3.62864857 |
| 33 | trophectodermal cell differentiation (GO:0001829) | 3.59166268 |
| 34 | male meiosis I (GO:0007141) | 3.59138687 |
| 35 | synapsis (GO:0007129) | 3.55350832 |
| 36 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 3.54015788 |
| 37 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.52609203 |
| 38 | protein complex disassembly (GO:0043241) | 3.52233644 |
| 39 | diol metabolic process (GO:0034311) | 3.43081507 |
| 40 | DNA-dependent DNA replication (GO:0006261) | 3.40261377 |
| 41 | macromolecular complex disassembly (GO:0032984) | 3.34727139 |
| 42 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.28300133 |
| 43 | branched-chain amino acid metabolic process (GO:0009081) | 3.26821532 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.25312331 |
| 45 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.25312331 |
| 46 | NADH dehydrogenase complex assembly (GO:0010257) | 3.25312331 |
| 47 | translation (GO:0006412) | 3.24933292 |
| 48 | urinary tract smooth muscle contraction (GO:0014848) | 3.19122128 |
| 49 | reciprocal DNA recombination (GO:0035825) | 3.18746205 |
| 50 | reciprocal meiotic recombination (GO:0007131) | 3.18746205 |
| 51 | DNA strand renaturation (GO:0000733) | 3.16710486 |
| 52 | olfactory bulb development (GO:0021772) | 3.16683182 |
| 53 | chaperone-mediated protein transport (GO:0072321) | 3.13650598 |
| 54 | base-excision repair, AP site formation (GO:0006285) | 3.11756466 |
| 55 | ribosomal large subunit biogenesis (GO:0042273) | 3.07125832 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.05686468 |
| 57 | protein targeting to membrane (GO:0006612) | 3.04321778 |
| 58 | ATP synthesis coupled proton transport (GO:0015986) | 3.03512264 |
| 59 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.03512264 |
| 60 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.02473016 |
| 61 | neuron remodeling (GO:0016322) | 3.01348367 |
| 62 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.00510584 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.97949524 |
| 64 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.97949524 |
| 65 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.97721209 |
| 66 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.97721209 |
| 67 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.96213890 |
| 68 | protein complex biogenesis (GO:0070271) | 2.96010137 |
| 69 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 2.95478440 |
| 70 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.94308683 |
| 71 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.92278120 |
| 72 | L-serine metabolic process (GO:0006563) | 2.91628699 |
| 73 | meiosis I (GO:0007127) | 2.86702335 |
| 74 | response to folic acid (GO:0051593) | 2.86612351 |
| 75 | sphingoid metabolic process (GO:0046519) | 2.86531332 |
| 76 | GTP biosynthetic process (GO:0006183) | 2.84665861 |
| 77 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.80214504 |
| 78 | positive regulation of skeletal muscle tissue development (GO:0048643) | 2.76801677 |
| 79 | regulation of immunoglobulin secretion (GO:0051023) | 2.76223609 |
| 80 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.74872228 |
| 81 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.74388760 |
| 82 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.71580280 |
| 83 | cellular component biogenesis (GO:0044085) | 2.70982449 |
| 84 | blood vessel maturation (GO:0001955) | 2.67670591 |
| 85 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.66410438 |
| 86 | pattern specification involved in kidney development (GO:0061004) | 2.59120989 |
| 87 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.56236816 |
| 88 | mRNA catabolic process (GO:0006402) | 2.54097984 |
| 89 | UTP biosynthetic process (GO:0006228) | 2.53122477 |
| 90 | monoamine transport (GO:0015844) | 2.53065101 |
| 91 | regulation of icosanoid secretion (GO:0032303) | 2.52709079 |
| 92 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.52086073 |
| 93 | negative regulation of B cell apoptotic process (GO:0002903) | 2.51759749 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.51334132 |
| 95 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 2.48856950 |
| 96 | rRNA processing (GO:0006364) | 2.48510606 |
| 97 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.46310796 |
| 98 | maturation of SSU-rRNA (GO:0030490) | 13.4037102 |
| 99 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 13.2243651 |
| 100 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 12.0765695 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.51608335 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.12561809 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.49398819 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.02320873 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.90275912 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.87809395 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.79325129 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.76375399 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.36856191 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.35071253 |
| 11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.30024489 |
| 12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.24459252 |
| 13 | TP53_22573176_ChIP-Seq_HFKS_Human | 2.15411008 |
| 14 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.10804600 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.02532374 |
| 16 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.02419609 |
| 17 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.97128749 |
| 18 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.96437660 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.95525682 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94870758 |
| 21 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.83622178 |
| 22 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.78740340 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.77131718 |
| 24 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.71389596 |
| 25 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.70516054 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.70086250 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.66931335 |
| 28 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.65462077 |
| 29 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.56920221 |
| 30 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.48815026 |
| 31 | ERA_21632823_ChIP-Seq_H3396_Human | 1.47352152 |
| 32 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.45426216 |
| 33 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.44965582 |
| 34 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.42807780 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.41539232 |
| 36 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39715790 |
| 37 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.33801400 |
| 38 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.33767050 |
| 39 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.33381918 |
| 40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30339346 |
| 41 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26804425 |
| 42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.26519431 |
| 43 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.23986661 |
| 44 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.23026097 |
| 45 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.20790285 |
| 46 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.19319342 |
| 47 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.19064883 |
| 48 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.14544328 |
| 49 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13212424 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.13207600 |
| 51 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.12993727 |
| 52 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12470519 |
| 53 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.12356211 |
| 54 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.11632895 |
| 55 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.10191688 |
| 56 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.10046667 |
| 57 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.09997003 |
| 58 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09133351 |
| 59 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.08998413 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08290177 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.06811277 |
| 62 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.05747196 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.04983635 |
| 64 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.04250747 |
| 65 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.03393059 |
| 66 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.03109082 |
| 67 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.02408079 |
| 68 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.02108094 |
| 69 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.00049662 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.98549867 |
| 71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.98549867 |
| 72 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.97367899 |
| 73 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97256878 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.97113130 |
| 75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.94645353 |
| 76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94332442 |
| 77 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94332442 |
| 78 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.94247393 |
| 79 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.93613883 |
| 80 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.92511754 |
| 81 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91619923 |
| 82 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.91339988 |
| 83 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.91318656 |
| 84 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.91137899 |
| 85 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.90461008 |
| 86 | TP53_16413492_ChIP-PET_HCT116_Human | 0.90017620 |
| 87 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.87692668 |
| 88 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.87535089 |
| 89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.87206984 |
| 90 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.86725828 |
| 91 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.86339676 |
| 92 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.86178766 |
| 93 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.85509651 |
| 94 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.85037293 |
| 95 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.85009343 |
| 96 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.84001383 |
| 97 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.82867286 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.82579846 |
| 99 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.80878403 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.80377158 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 5.47578284 |
| 2 | MP0001529_abnormal_vocalization | 5.14854605 |
| 3 | MP0002138_abnormal_hepatobiliary_system | 4.63879462 |
| 4 | MP0003195_calcinosis | 4.01451372 |
| 5 | MP0006292_abnormal_olfactory_placode | 4.01406993 |
| 6 | MP0003567_abnormal_fetal_cardiomyocyte | 3.24409347 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.88764993 |
| 8 | MP0001348_abnormal_lacrimal_gland | 2.71996353 |
| 9 | MP0004147_increased_porphyrin_level | 2.55423055 |
| 10 | MP0002102_abnormal_ear_morphology | 2.31264223 |
| 11 | MP0006054_spinal_hemorrhage | 2.20328687 |
| 12 | MP0001986_abnormal_taste_sensitivity | 2.08143774 |
| 13 | MP0001984_abnormal_olfaction | 2.07991436 |
| 14 | MP0003136_yellow_coat_color | 1.95567253 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 1.89503595 |
| 16 | MP0002160_abnormal_reproductive_system | 1.84072127 |
| 17 | MP0004142_abnormal_muscle_tone | 1.79566930 |
| 18 | MP0004885_abnormal_endolymph | 1.77766519 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.76112957 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.73873296 |
| 21 | MP0008789_abnormal_olfactory_epithelium | 1.71694277 |
| 22 | MP0010234_abnormal_vibrissa_follicle | 1.65283364 |
| 23 | MP0002163_abnormal_gland_morphology | 1.60175077 |
| 24 | MP0010094_abnormal_chromosome_stability | 1.49294893 |
| 25 | MP0005551_abnormal_eye_electrophysiolog | 1.48043986 |
| 26 | MP0005310_abnormal_salivary_gland | 1.44357035 |
| 27 | MP0003936_abnormal_reproductive_system | 1.40708412 |
| 28 | MP0000462_abnormal_digestive_system | 1.39853638 |
| 29 | MP0003646_muscle_fatigue | 1.39511831 |
| 30 | MP0005394_taste/olfaction_phenotype | 1.38900195 |
| 31 | MP0005499_abnormal_olfactory_system | 1.38900195 |
| 32 | MP0008872_abnormal_physiological_respon | 1.38381021 |
| 33 | MP0000613_abnormal_salivary_gland | 1.36343167 |
| 34 | MP0003011_delayed_dark_adaptation | 1.35117454 |
| 35 | MP0005360_urolithiasis | 1.34406667 |
| 36 | MP0006276_abnormal_autonomic_nervous | 1.32535850 |
| 37 | MP0005389_reproductive_system_phenotype | 1.31817812 |
| 38 | MP0008877_abnormal_DNA_methylation | 1.31415985 |
| 39 | MP0000750_abnormal_muscle_regeneration | 1.30332758 |
| 40 | MP0001968_abnormal_touch/_nociception | 1.26336913 |
| 41 | MP0005671_abnormal_response_to | 1.25321265 |
| 42 | MP0002736_abnormal_nociception_after | 1.23346078 |
| 43 | MP0002557_abnormal_social/conspecific_i | 1.18310574 |
| 44 | MP0003879_abnormal_hair_cell | 1.17211542 |
| 45 | MP0001293_anophthalmia | 1.16992861 |
| 46 | MP0003283_abnormal_digestive_organ | 1.16092122 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.15087468 |
| 48 | MP0003878_abnormal_ear_physiology | 1.12460317 |
| 49 | MP0005377_hearing/vestibular/ear_phenot | 1.12460317 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.11516650 |
| 51 | MP0000627_abnormal_mammary_gland | 1.09305760 |
| 52 | MP0001970_abnormal_pain_threshold | 1.07637907 |
| 53 | MP0002653_abnormal_ependyma_morphology | 1.05023457 |
| 54 | MP0004924_abnormal_behavior | 1.04165382 |
| 55 | MP0005386_behavior/neurological_phenoty | 1.04165382 |
| 56 | MP0001440_abnormal_grooming_behavior | 1.03535483 |
| 57 | MP0000372_irregular_coat_pigmentation | 1.02713534 |
| 58 | MP0003252_abnormal_bile_duct | 1.00187217 |
| 59 | MP0002733_abnormal_thermal_nociception | 0.99016043 |
| 60 | MP0001119_abnormal_female_reproductive | 0.96914156 |
| 61 | MP0003183_abnormal_peptide_metabolism | 0.96680145 |
| 62 | MP0002234_abnormal_pharynx_morphology | 0.95595157 |
| 63 | MP0002210_abnormal_sex_determination | 0.94866106 |
| 64 | MP0002272_abnormal_nervous_system | 0.94505050 |
| 65 | MP0001485_abnormal_pinna_reflex | 0.93065246 |
| 66 | MP0004133_heterotaxia | 0.91855684 |
| 67 | MP0009745_abnormal_behavioral_response | 0.91575798 |
| 68 | MP0004742_abnormal_vestibular_system | 0.91461622 |
| 69 | MP0005410_abnormal_fertilization | 0.91363384 |
| 70 | MP0000049_abnormal_middle_ear | 0.90720484 |
| 71 | MP0001800_abnormal_humoral_immune | 0.84257605 |
| 72 | MP0003718_maternal_effect | 0.83767030 |
| 73 | MP0005423_abnormal_somatic_nervous | 0.83524777 |
| 74 | MP0002928_abnormal_bile_duct | 0.82706761 |
| 75 | MP0001905_abnormal_dopamine_level | 0.80743291 |
| 76 | MP0005253_abnormal_eye_physiology | 0.80465297 |
| 77 | MP0002734_abnormal_mechanical_nocicepti | 0.80350151 |
| 78 | MP0002938_white_spotting | 0.77304597 |
| 79 | MP0001919_abnormal_reproductive_system | 0.76408605 |
| 80 | MP0008058_abnormal_DNA_repair | 0.76145354 |
| 81 | MP0003806_abnormal_nucleotide_metabolis | 0.75414803 |
| 82 | MP0005195_abnormal_posterior_eye | 0.74496781 |
| 83 | MP0005379_endocrine/exocrine_gland_phen | 0.74352750 |
| 84 | MP0001663_abnormal_digestive_system | 0.73775523 |
| 85 | MP0005084_abnormal_gallbladder_morpholo | 0.72817764 |
| 86 | MP0000631_abnormal_neuroendocrine_gland | 0.72135226 |
| 87 | MP0003890_abnormal_embryonic-extraembry | 0.71817357 |
| 88 | MP0005332_abnormal_amino_acid | 0.71623425 |
| 89 | MP0001145_abnormal_male_reproductive | 0.70645060 |
| 90 | MP0002638_abnormal_pupillary_reflex | 0.69711291 |
| 91 | MP0003698_abnormal_male_reproductive | 0.68932632 |
| 92 | MP0003880_abnormal_central_pattern | 0.68687301 |
| 93 | MP0001764_abnormal_homeostasis | 0.68384695 |
| 94 | MP0005645_abnormal_hypothalamus_physiol | 0.68302758 |
| 95 | MP0002752_abnormal_somatic_nervous | 0.68278583 |
| 96 | MP0003635_abnormal_synaptic_transmissio | 0.68041202 |
| 97 | MP0003787_abnormal_imprinting | 0.66999599 |
| 98 | MP0000653_abnormal_sex_gland | 0.64989288 |
| 99 | MP0002452_abnormal_antigen_presenting | 0.62251197 |
| 100 | MP0000778_abnormal_nervous_system | 0.62188357 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nasal polyposis (HP:0100582) | 9.86464904 |
| 2 | Chronic sinusitis (HP:0011109) | 8.93607675 |
| 3 | Abnormality of the nasal mucosa (HP:0000433) | 8.17992861 |
| 4 | Hypothermia (HP:0002045) | 6.95931324 |
| 5 | Recurrent bronchitis (HP:0002837) | 6.74646780 |
| 6 | Abnormal rod and cone electroretinograms (HP:0008323) | 5.07107256 |
| 7 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.97938685 |
| 8 | Bronchitis (HP:0012387) | 4.44107341 |
| 9 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.51227967 |
| 10 | Bronchiectasis (HP:0002110) | 3.25875753 |
| 11 | Ectopia lentis (HP:0001083) | 3.14936986 |
| 12 | Enlarged epiphyses (HP:0010580) | 3.06703969 |
| 13 | Impulsivity (HP:0100710) | 2.94844341 |
| 14 | Acute necrotizing encephalopathy (HP:0006965) | 2.87575324 |
| 15 | Emphysema (HP:0002097) | 2.85602958 |
| 16 | Medial flaring of the eyebrow (HP:0010747) | 2.84938571 |
| 17 | Colon cancer (HP:0003003) | 2.82050436 |
| 18 | Exotropia (HP:0000577) | 2.71994266 |
| 19 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.70917614 |
| 20 | Reticulocytopenia (HP:0001896) | 2.69741617 |
| 21 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.56120980 |
| 22 | Abnormality of alanine metabolism (HP:0010916) | 2.56120980 |
| 23 | Hyperalaninemia (HP:0003348) | 2.56120980 |
| 24 | Gait imbalance (HP:0002141) | 2.54880450 |
| 25 | Septo-optic dysplasia (HP:0100842) | 2.51962734 |
| 26 | Abolished electroretinogram (ERG) (HP:0000550) | 2.50464891 |
| 27 | Congenital primary aphakia (HP:0007707) | 2.42908035 |
| 28 | Deep palmar crease (HP:0006191) | 2.38809063 |
| 29 | Progressive macrocephaly (HP:0004481) | 2.38247365 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.36477278 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.36477278 |
| 32 | Thyroid-stimulating hormone excess (HP:0002925) | 2.33893968 |
| 33 | Constricted visual fields (HP:0001133) | 2.33647104 |
| 34 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.31777799 |
| 35 | Decreased central vision (HP:0007663) | 2.29784976 |
| 36 | Acute encephalopathy (HP:0006846) | 2.29503198 |
| 37 | Abnormal number of erythroid precursors (HP:0012131) | 2.28880611 |
| 38 | Attenuation of retinal blood vessels (HP:0007843) | 2.27217517 |
| 39 | Nephrogenic diabetes insipidus (HP:0009806) | 2.22973291 |
| 40 | Clumsiness (HP:0002312) | 2.21587495 |
| 41 | Congenital stationary night blindness (HP:0007642) | 2.21366631 |
| 42 | Thickened helices (HP:0000391) | 2.20419210 |
| 43 | Pustule (HP:0200039) | 2.16755643 |
| 44 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 2.16301039 |
| 45 | Mitochondrial inheritance (HP:0001427) | 2.11701948 |
| 46 | Alveolar cell carcinoma (HP:0006519) | 2.11551172 |
| 47 | Flattened epiphyses (HP:0003071) | 2.08019504 |
| 48 | Increased CSF lactate (HP:0002490) | 2.07046319 |
| 49 | Hepatocellular necrosis (HP:0001404) | 2.04098312 |
| 50 | Chronic otitis media (HP:0000389) | 13.7297765 |
| 51 | Abnormality of the femoral head (HP:0003368) | 1.95441890 |
| 52 | Absent thumb (HP:0009777) | 1.94748446 |
| 53 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.93988476 |
| 54 | Abnormality of femoral epiphyses (HP:0006499) | 1.93988476 |
| 55 | Thick nail (HP:0001805) | 1.92920010 |
| 56 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.92310804 |
| 57 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.92310804 |
| 58 | Macrocytic anemia (HP:0001972) | 1.92222033 |
| 59 | Amelogenesis imperfecta (HP:0000705) | 1.88266555 |
| 60 | Nephronophthisis (HP:0000090) | 1.87905633 |
| 61 | Vaginal atresia (HP:0000148) | 1.87710935 |
| 62 | Type II lissencephaly (HP:0007260) | 1.86989073 |
| 63 | Hypophosphatemic rickets (HP:0004912) | 1.84429795 |
| 64 | Agammaglobulinemia (HP:0004432) | 1.83967526 |
| 65 | Abnormality of the vertebral endplates (HP:0005106) | 1.83672849 |
| 66 | Lethargy (HP:0001254) | 1.83332869 |
| 67 | Optic disc pallor (HP:0000543) | 1.82305633 |
| 68 | Genital tract atresia (HP:0001827) | 1.80528199 |
| 69 | Recurrent bacterial skin infections (HP:0005406) | 1.79534761 |
| 70 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.77024229 |
| 71 | Absent/shortened dynein arms (HP:0200106) | 1.76078635 |
| 72 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.76078635 |
| 73 | Pancreatic fibrosis (HP:0100732) | 1.75143905 |
| 74 | Slow-growing hair (HP:0002217) | 1.74526409 |
| 75 | Abnormality of hair growth rate (HP:0011363) | 1.74526409 |
| 76 | Cerebral edema (HP:0002181) | 1.74496911 |
| 77 | Maternal diabetes (HP:0009800) | 1.72977001 |
| 78 | Premature loss of primary teeth (HP:0006323) | 1.70619940 |
| 79 | Poor coordination (HP:0002370) | 1.68027346 |
| 80 | Fibular aplasia (HP:0002990) | 1.67892392 |
| 81 | Global brain atrophy (HP:0002283) | 1.67611882 |
| 82 | Abnormal ciliary motility (HP:0012262) | 1.65764541 |
| 83 | Hepatic necrosis (HP:0002605) | 1.64597798 |
| 84 | Lipid accumulation in hepatocytes (HP:0006561) | 1.64566276 |
| 85 | Increased hepatocellular lipid droplets (HP:0006565) | 1.60311685 |
| 86 | Hypoplasia of the radius (HP:0002984) | 1.58930142 |
| 87 | Generalized amyotrophy (HP:0003700) | 1.56763854 |
| 88 | 11 pairs of ribs (HP:0000878) | 1.56093947 |
| 89 | Supernumerary spleens (HP:0009799) | 1.52163362 |
| 90 | Renal Fanconi syndrome (HP:0001994) | 1.51335936 |
| 91 | Long palpebral fissure (HP:0000637) | 1.51173110 |
| 92 | Pancreatic cysts (HP:0001737) | 1.51082499 |
| 93 | Retinitis pigmentosa (HP:0000510) | 1.49297256 |
| 94 | True hermaphroditism (HP:0010459) | 1.47382923 |
| 95 | Abnormal drinking behavior (HP:0030082) | 1.47377182 |
| 96 | Polydipsia (HP:0001959) | 1.47377182 |
| 97 | Hyperglycinemia (HP:0002154) | 1.47264550 |
| 98 | Abnormality of the labia minora (HP:0012880) | 1.46329145 |
| 99 | Abnormality of the renal medulla (HP:0100957) | 1.44839855 |
| 100 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.44413538 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 5.37512905 |
| 2 | ARAF | 4.17059978 |
| 3 | MAP3K9 | 4.13649359 |
| 4 | TAOK3 | 3.22251971 |
| 5 | BRAF | 2.89399935 |
| 6 | BMPR2 | 2.20090468 |
| 7 | MAP3K14 | 2.16661463 |
| 8 | MAP4K2 | 2.05868081 |
| 9 | MAP3K13 | 10.8287335 |
| 10 | TXK | 1.90176029 |
| 11 | MOS | 1.83126882 |
| 12 | WNK4 | 1.41531350 |
| 13 | ZAK | 1.32045648 |
| 14 | CASK | 1.15597214 |
| 15 | ILK | 1.13645673 |
| 16 | STK39 | 0.99742625 |
| 17 | NEK2 | 0.98773953 |
| 18 | KSR1 | 0.97004699 |
| 19 | MAP3K8 | 0.96885880 |
| 20 | ADRBK2 | 0.94359204 |
| 21 | NEK1 | 0.93189630 |
| 22 | DYRK2 | 0.90136821 |
| 23 | STK38L | 0.89038313 |
| 24 | KSR2 | 0.87860232 |
| 25 | GRK1 | 0.86690822 |
| 26 | TSSK6 | 0.84573208 |
| 27 | WNK3 | 0.83421638 |
| 28 | MAP3K7 | 0.83054844 |
| 29 | BMPR1B | 0.80322430 |
| 30 | IKBKB | 0.79226881 |
| 31 | TNIK | 0.78932653 |
| 32 | MARK1 | 0.78393712 |
| 33 | MAP3K12 | 0.77353075 |
| 34 | EPHA2 | 0.75735520 |
| 35 | BCKDK | 0.74286861 |
| 36 | MAPK13 | 0.73225260 |
| 37 | RAF1 | 0.72357689 |
| 38 | STK16 | 0.70690182 |
| 39 | CHUK | 0.68104739 |
| 40 | EIF2AK1 | 0.65746150 |
| 41 | PLK4 | 0.65225912 |
| 42 | FRK | 0.59885890 |
| 43 | PRKCQ | 0.57755627 |
| 44 | MKNK2 | 0.55464185 |
| 45 | STK3 | 0.54186334 |
| 46 | PINK1 | 0.54071562 |
| 47 | TIE1 | 0.53240395 |
| 48 | TRIM28 | 0.52439932 |
| 49 | BTK | 0.52095039 |
| 50 | MST4 | 0.49684875 |
| 51 | NTRK2 | 0.46182692 |
| 52 | MAP3K4 | 0.45729378 |
| 53 | CDC7 | 0.45723652 |
| 54 | OXSR1 | 0.45336146 |
| 55 | PBK | 0.43920249 |
| 56 | TAF1 | 0.42879089 |
| 57 | ACVR1B | 0.42365791 |
| 58 | MAP4K1 | 0.42262343 |
| 59 | DAPK3 | 0.39810030 |
| 60 | PLK1 | 0.39779151 |
| 61 | TESK1 | 0.39054271 |
| 62 | ATR | 0.37899013 |
| 63 | TEC | 0.36706473 |
| 64 | TGFBR1 | 0.35664263 |
| 65 | MAP2K2 | 0.34461815 |
| 66 | PIM2 | 0.31545002 |
| 67 | NUAK1 | 0.30956292 |
| 68 | INSRR | 0.30647659 |
| 69 | DAPK2 | 0.30582614 |
| 70 | PLK3 | 0.30153230 |
| 71 | PAK3 | 0.29996046 |
| 72 | PRKCG | 0.29762378 |
| 73 | MINK1 | 0.29567140 |
| 74 | NME1 | 0.28019694 |
| 75 | EIF2AK2 | 0.27302332 |
| 76 | PRKAA2 | 0.27120774 |
| 77 | HCK | 0.25461377 |
| 78 | CSNK2A1 | 0.25386765 |
| 79 | FES | 0.25276907 |
| 80 | CDK14 | 0.24215564 |
| 81 | AURKB | 0.23780800 |
| 82 | VRK2 | 0.23341640 |
| 83 | PHKG2 | 0.22735049 |
| 84 | PHKG1 | 0.22735049 |
| 85 | SGK1 | 0.21349529 |
| 86 | CSNK2A2 | 0.20472503 |
| 87 | OBSCN | 0.18310091 |
| 88 | PRKCZ | 0.18308288 |
| 89 | PASK | 0.17782368 |
| 90 | ADRBK1 | 0.17304512 |
| 91 | VRK1 | 0.17199844 |
| 92 | PRKACA | 0.15942702 |
| 93 | CHEK1 | 0.15405801 |
| 94 | IGF1R | 0.14839359 |
| 95 | MKNK1 | 0.14732077 |
| 96 | STK38 | 0.14006395 |
| 97 | ATM | 0.13365814 |
| 98 | LYN | 0.12666924 |
| 99 | CDK18 | 0.11330524 |
| 100 | MYLK | 0.11313939 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.46382773 |
| 2 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.38288392 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34047064 |
| 4 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.27468703 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.69463985 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.62158617 |
| 7 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.19962371 |
| 8 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.16779910 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.13891610 |
| 10 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.10441364 |
| 11 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.93887844 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.91293837 |
| 13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.90310324 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.87679986 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.80104944 |
| 16 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.74954446 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.68321482 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.60988836 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.60117664 |
| 20 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.55995673 |
| 21 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.55753191 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.54367160 |
| 23 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.47884576 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.47485212 |
| 25 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.46939866 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.46647419 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.46628723 |
| 28 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.45858495 |
| 29 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.41288658 |
| 30 | RNA polymerase_Homo sapiens_hsa03020 | 1.39646219 |
| 31 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.38816106 |
| 32 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.38593315 |
| 33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.28462817 |
| 34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.24835061 |
| 35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.22422918 |
| 36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.21579715 |
| 37 | Nicotine addiction_Homo sapiens_hsa05033 | 1.19381661 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.13471176 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.10609384 |
| 40 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.08925400 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.05265102 |
| 42 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.02736560 |
| 43 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.00958757 |
| 44 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.99925824 |
| 45 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.99802416 |
| 46 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97751313 |
| 47 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.95604926 |
| 48 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.93772005 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.88184442 |
| 50 | Protein export_Homo sapiens_hsa03060 | 0.83570050 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.81132710 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.79478246 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72356952 |
| 54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.70285021 |
| 55 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67185699 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66740711 |
| 57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.66299154 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.65551324 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60965502 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60776489 |
| 61 | Spliceosome_Homo sapiens_hsa03040 | 0.59666748 |
| 62 | Apoptosis_Homo sapiens_hsa04210 | 0.58439493 |
| 63 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.58133919 |
| 64 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56185738 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53849969 |
| 66 | Mismatch repair_Homo sapiens_hsa03430 | 0.52698661 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52443684 |
| 68 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51595937 |
| 69 | Mineral absorption_Homo sapiens_hsa04978 | 0.51520792 |
| 70 | Insulin secretion_Homo sapiens_hsa04911 | 0.51033068 |
| 71 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.50877323 |
| 72 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.50824269 |
| 73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.47616818 |
| 74 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.45093170 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42721875 |
| 76 | Taste transduction_Homo sapiens_hsa04742 | 0.37652855 |
| 77 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.37011636 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34918016 |
| 79 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34906284 |
| 80 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34703218 |
| 81 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.34623174 |
| 82 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33718875 |
| 83 | Purine metabolism_Homo sapiens_hsa00230 | 0.33391949 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.30886370 |
| 85 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30805491 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30554825 |
| 87 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.27881548 |
| 88 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.27084694 |
| 89 | RNA transport_Homo sapiens_hsa03013 | 0.26251290 |
| 90 | Thyroid cancer_Homo sapiens_hsa05216 | 0.25827117 |
| 91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.24568103 |
| 92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.23527651 |
| 93 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.23506223 |
| 94 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22902620 |
| 95 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.21749267 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.19070402 |
| 97 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.16547734 |
| 98 | Base excision repair_Homo sapiens_hsa03410 | 0.15463743 |
| 99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.14009533 |
| 100 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.12992404 |

