

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chaperone-mediated protein transport (GO:0072321) | 6.51495073 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.02981276 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.02981276 |
| 4 | viral transcription (GO:0019083) | 5.85433826 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 5.71131702 |
| 6 | translational termination (GO:0006415) | 5.62458939 |
| 7 | DNA deamination (GO:0045006) | 5.58546076 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.40396391 |
| 9 | translational elongation (GO:0006414) | 5.18878715 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.96217441 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 4.87663351 |
| 12 | protein targeting to ER (GO:0045047) | 4.85727548 |
| 13 | ribosomal small subunit biogenesis (GO:0042274) | 4.72120193 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.63500142 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.60478173 |
| 16 | maturation of SSU-rRNA (GO:0030490) | 4.39918558 |
| 17 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.39702285 |
| 18 | ribosomal large subunit biogenesis (GO:0042273) | 4.38448143 |
| 19 | protein neddylation (GO:0045116) | 4.38134289 |
| 20 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.28974741 |
| 21 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.28974741 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.19291372 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.17742443 |
| 24 | viral life cycle (GO:0019058) | 4.15471504 |
| 25 | translational initiation (GO:0006413) | 4.00466788 |
| 26 | cytidine metabolic process (GO:0046087) | 3.94573430 |
| 27 | cytidine catabolic process (GO:0006216) | 3.94573430 |
| 28 | cytidine deamination (GO:0009972) | 3.94573430 |
| 29 | respiratory electron transport chain (GO:0022904) | 3.92690425 |
| 30 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.91136283 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.89930834 |
| 32 | electron transport chain (GO:0022900) | 3.88677011 |
| 33 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.81634946 |
| 34 | translation (GO:0006412) | 3.77221916 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.72891966 |
| 36 | protein complex biogenesis (GO:0070271) | 3.67026643 |
| 37 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.63080758 |
| 38 | ATP biosynthetic process (GO:0006754) | 3.58988988 |
| 39 | response to pheromone (GO:0019236) | 3.58621601 |
| 40 | GDP-mannose metabolic process (GO:0019673) | 3.54324551 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.54024979 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.54024979 |
| 43 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.54024979 |
| 44 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.53505907 |
| 45 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.51516807 |
| 46 | interferon-gamma production (GO:0032609) | 3.45719827 |
| 47 | protein complex disassembly (GO:0043241) | 3.42054933 |
| 48 | cellular component biogenesis (GO:0044085) | 3.41206069 |
| 49 | nucleoside transmembrane transport (GO:1901642) | 3.32635095 |
| 50 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.32270292 |
| 51 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.31539095 |
| 52 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.30502835 |
| 53 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.29403607 |
| 54 | GTP biosynthetic process (GO:0006183) | 3.27854902 |
| 55 | macromolecular complex disassembly (GO:0032984) | 3.26248780 |
| 56 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.23032847 |
| 57 | behavioral response to nicotine (GO:0035095) | 3.22921149 |
| 58 | protein targeting to membrane (GO:0006612) | 3.22426065 |
| 59 | base-excision repair, AP site formation (GO:0006285) | 3.17673027 |
| 60 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.05814169 |
| 61 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.02764203 |
| 62 | rRNA modification (GO:0000154) | 2.94644974 |
| 63 | rRNA processing (GO:0006364) | 2.90472042 |
| 64 | hydrogen ion transmembrane transport (GO:1902600) | 2.88416001 |
| 65 | rRNA metabolic process (GO:0016072) | 2.88403523 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.86926712 |
| 67 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.86926712 |
| 68 | mRNA catabolic process (GO:0006402) | 2.86546468 |
| 69 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.84183602 |
| 70 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.81853437 |
| 71 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81845154 |
| 72 | regulation of regulatory T cell differentiation (GO:0045589) | 2.79875444 |
| 73 | proton transport (GO:0015992) | 2.70844697 |
| 74 | UTP biosynthetic process (GO:0006228) | 2.70708944 |
| 75 | protein-cofactor linkage (GO:0018065) | 2.69863959 |
| 76 | ubiquinone biosynthetic process (GO:0006744) | 2.69093668 |
| 77 | proteasome assembly (GO:0043248) | 2.68773406 |
| 78 | maturation of 5.8S rRNA (GO:0000460) | 2.66612888 |
| 79 | hydrogen transport (GO:0006818) | 2.66359430 |
| 80 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.66143285 |
| 81 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.66131996 |
| 82 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.65024713 |
| 83 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.64351569 |
| 84 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.61678708 |
| 85 | RNA catabolic process (GO:0006401) | 2.59842343 |
| 86 | protein targeting to mitochondrion (GO:0006626) | 2.57761942 |
| 87 | UTP metabolic process (GO:0046051) | 2.56103274 |
| 88 | intracellular protein transmembrane import (GO:0044743) | 2.55482662 |
| 89 | positive regulation of fatty acid transport (GO:2000193) | 2.54046885 |
| 90 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.53741609 |
| 91 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.53741609 |
| 92 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.53741609 |
| 93 | pseudouridine synthesis (GO:0001522) | 2.53056063 |
| 94 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.51849904 |
| 95 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.51849904 |
| 96 | regulation of chronic inflammatory response (GO:0002676) | 2.48418222 |
| 97 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.47442870 |
| 98 | positive regulation of defense response to virus by host (GO:0002230) | 2.46598103 |
| 99 | deoxyribonucleotide catabolic process (GO:0009264) | 2.46131504 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.44767910 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.52234436 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.89702155 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.56315385 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.51921402 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.48485006 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.34241129 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.31977185 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.26583574 |
| 9 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.15902450 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01989302 |
| 11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.89745996 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.81749733 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78551183 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38867843 |
| 15 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.30905920 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.30562908 |
| 17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.18385817 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.98833399 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96731933 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.87054957 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.82337392 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.79135339 |
| 23 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.77613019 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.74142689 |
| 25 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.64415473 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62943885 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.61589988 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.58919696 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.57894650 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.56503860 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53417349 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.50548122 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.47159222 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.47096497 |
| 35 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.38015760 |
| 36 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37518472 |
| 37 | EWS_26573619_Chip-Seq_HEK293_Human | 1.36156641 |
| 38 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.35668955 |
| 39 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.30785327 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.28546495 |
| 41 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27816364 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.25491747 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24527159 |
| 44 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.24096976 |
| 45 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23948598 |
| 46 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23078097 |
| 47 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.22688108 |
| 48 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.22204240 |
| 49 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.21160692 |
| 50 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20512109 |
| 51 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.20244553 |
| 52 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.17543790 |
| 53 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15872127 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.14691056 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.14691056 |
| 56 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14578811 |
| 57 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.14088699 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.13763770 |
| 59 | GATA3_26560356_Chip-Seq_TH2_Human | 1.13046008 |
| 60 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.12521026 |
| 61 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.11954358 |
| 62 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.09732791 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.09732331 |
| 64 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08006895 |
| 65 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.07515515 |
| 66 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.07139244 |
| 67 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06111846 |
| 68 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.05303068 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.05179052 |
| 70 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.04101755 |
| 71 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.00813642 |
| 72 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00658075 |
| 73 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.00438012 |
| 74 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.99846388 |
| 75 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.97825006 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96125287 |
| 77 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.94119693 |
| 78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.94017631 |
| 79 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.93894417 |
| 80 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.92944260 |
| 81 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.92911235 |
| 82 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.92512790 |
| 83 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.91254787 |
| 84 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.90487085 |
| 85 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.90487085 |
| 86 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.90374638 |
| 87 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.90246052 |
| 88 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.89842047 |
| 89 | ERA_21632823_ChIP-Seq_H3396_Human | 0.89152928 |
| 90 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89033393 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.89023902 |
| 92 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.88972900 |
| 93 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88483920 |
| 94 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.88417890 |
| 95 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.87835205 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87581081 |
| 97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.86224485 |
| 98 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85812096 |
| 99 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85753937 |
| 100 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.85620608 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.47762299 |
| 2 | MP0005671_abnormal_response_to | 3.19249890 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.11034132 |
| 4 | MP0002638_abnormal_pupillary_reflex | 2.97302129 |
| 5 | MP0002102_abnormal_ear_morphology | 2.64179069 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.50399860 |
| 7 | MP0003646_muscle_fatigue | 2.42575185 |
| 8 | MP0004145_abnormal_muscle_electrophysio | 2.39832861 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.31951819 |
| 10 | MP0005646_abnormal_pituitary_gland | 2.22963892 |
| 11 | MP0003878_abnormal_ear_physiology | 2.15699728 |
| 12 | MP0005377_hearing/vestibular/ear_phenot | 2.15699728 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.07495409 |
| 14 | MP0004142_abnormal_muscle_tone | 1.99526291 |
| 15 | MP0000372_irregular_coat_pigmentation | 1.96195838 |
| 16 | MP0002163_abnormal_gland_morphology | 1.88714395 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.87342856 |
| 18 | MP0005084_abnormal_gallbladder_morpholo | 1.77975553 |
| 19 | MP0005551_abnormal_eye_electrophysiolog | 1.77548842 |
| 20 | MP0004885_abnormal_endolymph | 1.77241538 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.76394350 |
| 22 | MP0008872_abnormal_physiological_respon | 1.76263105 |
| 23 | MP0001968_abnormal_touch/_nociception | 1.74964399 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.74306240 |
| 25 | MP0003011_delayed_dark_adaptation | 1.68181932 |
| 26 | MP0005389_reproductive_system_phenotype | 1.67251833 |
| 27 | MP0001986_abnormal_taste_sensitivity | 1.66164257 |
| 28 | MP0002160_abnormal_reproductive_system | 1.65342311 |
| 29 | MP0002138_abnormal_hepatobiliary_system | 1.64755829 |
| 30 | MP0001873_stomach_inflammation | 1.53834302 |
| 31 | MP0009785_altered_susceptibility_to | 1.53273756 |
| 32 | MP0009333_abnormal_splenocyte_physiolog | 1.48136752 |
| 33 | MP0002736_abnormal_nociception_after | 1.47160826 |
| 34 | MP0002277_abnormal_respiratory_mucosa | 1.46529364 |
| 35 | MP0001905_abnormal_dopamine_level | 1.43665775 |
| 36 | MP0004147_increased_porphyrin_level | 1.40515825 |
| 37 | MP0001919_abnormal_reproductive_system | 1.40504026 |
| 38 | MP0003787_abnormal_imprinting | 1.40421211 |
| 39 | MP0002876_abnormal_thyroid_physiology | 1.38910791 |
| 40 | MP0005379_endocrine/exocrine_gland_phen | 1.34959099 |
| 41 | MP0008789_abnormal_olfactory_epithelium | 1.29869827 |
| 42 | MP0003195_calcinosis | 1.26465894 |
| 43 | MP0005253_abnormal_eye_physiology | 1.22902583 |
| 44 | MP0002653_abnormal_ependyma_morphology | 1.20022071 |
| 45 | MP0002148_abnormal_hypersensitivity_rea | 1.18909409 |
| 46 | MP0002095_abnormal_skin_pigmentation | 1.16584961 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.14840226 |
| 48 | MP0001800_abnormal_humoral_immune | 1.13687161 |
| 49 | MP0006036_abnormal_mitochondrial_physio | 1.13505527 |
| 50 | MP0005075_abnormal_melanosome_morpholog | 1.12896840 |
| 51 | MP0002272_abnormal_nervous_system | 1.11146898 |
| 52 | MP0005000_abnormal_immune_tolerance | 1.08097526 |
| 53 | MP0003786_premature_aging | 1.05668674 |
| 54 | MP0000631_abnormal_neuroendocrine_gland | 1.03254926 |
| 55 | MP0002723_abnormal_immune_serum | 1.00640792 |
| 56 | MP0004043_abnormal_pH_regulation | 0.99837375 |
| 57 | MP0003806_abnormal_nucleotide_metabolis | 0.99738060 |
| 58 | MP0004133_heterotaxia | 0.98068502 |
| 59 | MP0003763_abnormal_thymus_physiology | 0.96947424 |
| 60 | MP0001293_anophthalmia | 0.95571035 |
| 61 | MP0001485_abnormal_pinna_reflex | 0.95475897 |
| 62 | MP0003567_abnormal_fetal_cardiomyocyte | 0.91538239 |
| 63 | MP0009764_decreased_sensitivity_to | 0.91271916 |
| 64 | MP0001790_abnormal_immune_system | 0.91052509 |
| 65 | MP0005387_immune_system_phenotype | 0.91052509 |
| 66 | MP0001984_abnormal_olfaction | 0.90656195 |
| 67 | MP0001764_abnormal_homeostasis | 0.90166530 |
| 68 | MP0001529_abnormal_vocalization | 0.87286467 |
| 69 | MP0002420_abnormal_adaptive_immunity | 0.86487392 |
| 70 | MP0009745_abnormal_behavioral_response | 0.86283517 |
| 71 | MP0003880_abnormal_central_pattern | 0.86072372 |
| 72 | MP0005394_taste/olfaction_phenotype | 0.84855106 |
| 73 | MP0005499_abnormal_olfactory_system | 0.84855106 |
| 74 | MP0000049_abnormal_middle_ear | 0.84598894 |
| 75 | MP0003866_abnormal_defecation | 0.83620388 |
| 76 | MP0001819_abnormal_immune_cell | 0.83317383 |
| 77 | MP0005636_abnormal_mineral_homeostasis | 0.82655702 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.82309359 |
| 79 | MP0004782_abnormal_surfactant_physiolog | 0.82128499 |
| 80 | MP0008058_abnormal_DNA_repair | 0.81951339 |
| 81 | MP0002938_white_spotting | 0.80963242 |
| 82 | MP0008775_abnormal_heart_ventricle | 0.80573525 |
| 83 | MP0005195_abnormal_posterior_eye | 0.80376524 |
| 84 | MP0001970_abnormal_pain_threshold | 0.79909251 |
| 85 | MP0002733_abnormal_thermal_nociception | 0.78809344 |
| 86 | MP0006035_abnormal_mitochondrial_morpho | 0.78191563 |
| 87 | MP0001440_abnormal_grooming_behavior | 0.77752808 |
| 88 | MP0003693_abnormal_embryo_hatching | 0.77723448 |
| 89 | MP0002693_abnormal_pancreas_physiology | 0.77491907 |
| 90 | MP0009250_abnormal_appendicular_skeleto | 0.76251836 |
| 91 | MP0008995_early_reproductive_senescence | 0.75860602 |
| 92 | MP0003186_abnormal_redox_activity | 0.75681353 |
| 93 | MP0001119_abnormal_female_reproductive | 0.75441764 |
| 94 | MP0005410_abnormal_fertilization | 0.75275424 |
| 95 | MP0001727_abnormal_embryo_implantation | 0.72383905 |
| 96 | MP0002210_abnormal_sex_determination | 0.71075687 |
| 97 | MP0010155_abnormal_intestine_physiology | 0.70894659 |
| 98 | MP0003137_abnormal_impulse_conducting | 0.70239508 |
| 99 | MP0002398_abnormal_bone_marrow | 0.69161290 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.69098152 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.44187689 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.33091521 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.93877121 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 3.91772289 |
| 5 | Increased CSF lactate (HP:0002490) | 3.91253760 |
| 6 | 3-Methylglutaconic aciduria (HP:0003535) | 3.87844147 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.67912032 |
| 8 | Congenital stationary night blindness (HP:0007642) | 3.63572571 |
| 9 | Acute encephalopathy (HP:0006846) | 3.62780223 |
| 10 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.48661975 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.45731777 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.44947480 |
| 13 | Hepatocellular necrosis (HP:0001404) | 3.39208979 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.37693671 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.37038699 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 3.35423182 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 3.35423182 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.28022787 |
| 19 | Macrocytic anemia (HP:0001972) | 3.18504789 |
| 20 | Pancreatic cysts (HP:0001737) | 3.14650550 |
| 21 | Hepatic necrosis (HP:0002605) | 3.11091742 |
| 22 | Increased intramyocellular lipid droplets (HP:0012240) | 3.05280448 |
| 23 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.02460378 |
| 24 | Cerebral edema (HP:0002181) | 2.97119441 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.94765533 |
| 26 | Abnormal number of erythroid precursors (HP:0012131) | 2.79807483 |
| 27 | IgG deficiency (HP:0004315) | 2.78768985 |
| 28 | Exertional dyspnea (HP:0002875) | 2.73376892 |
| 29 | True hermaphroditism (HP:0010459) | 2.71467318 |
| 30 | Methylmalonic aciduria (HP:0012120) | 2.67756077 |
| 31 | Abolished electroretinogram (ERG) (HP:0000550) | 2.64093022 |
| 32 | Decreased central vision (HP:0007663) | 2.63432642 |
| 33 | Stomatitis (HP:0010280) | 2.59191743 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.59148852 |
| 35 | Pallor (HP:0000980) | 2.55533244 |
| 36 | Optic disc pallor (HP:0000543) | 2.54328613 |
| 37 | Increased serum lactate (HP:0002151) | 2.52504449 |
| 38 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.50780102 |
| 39 | Lactic acidosis (HP:0003128) | 2.45055520 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.42625748 |
| 41 | Aplastic anemia (HP:0001915) | 2.42038424 |
| 42 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.39071201 |
| 43 | Absent/shortened dynein arms (HP:0200106) | 2.39071201 |
| 44 | Reticulocytopenia (HP:0001896) | 2.35199036 |
| 45 | Nephronophthisis (HP:0000090) | 2.34694790 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.32510464 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.32510464 |
| 48 | Hypoproteinemia (HP:0003075) | 2.24720681 |
| 49 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.22896982 |
| 50 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.22118634 |
| 51 | Abnormality of renal resorption (HP:0011038) | 2.19975135 |
| 52 | Glycosuria (HP:0003076) | 2.17239783 |
| 53 | Abnormality of urine glucose concentration (HP:0011016) | 2.17239783 |
| 54 | Congenital, generalized hypertrichosis (HP:0004540) | 2.16589797 |
| 55 | Abnormality of the renal cortex (HP:0011035) | 2.16249459 |
| 56 | Hyperphosphaturia (HP:0003109) | 2.15109126 |
| 57 | Abnormal drinking behavior (HP:0030082) | 2.13615969 |
| 58 | Polydipsia (HP:0001959) | 2.13615969 |
| 59 | Exercise intolerance (HP:0003546) | 2.09391066 |
| 60 | Respiratory failure (HP:0002878) | 2.08959576 |
| 61 | Type 2 muscle fiber atrophy (HP:0003554) | 2.07165444 |
| 62 | Hyperglycinemia (HP:0002154) | 2.06133002 |
| 63 | Medial flaring of the eyebrow (HP:0010747) | 2.05889961 |
| 64 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.05595155 |
| 65 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.05595155 |
| 66 | Hypoplasia of the pons (HP:0012110) | 2.05091732 |
| 67 | Absent thumb (HP:0009777) | 2.05088483 |
| 68 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.03019068 |
| 69 | Lethargy (HP:0001254) | 2.02092711 |
| 70 | Attenuation of retinal blood vessels (HP:0007843) | 2.01835738 |
| 71 | Respiratory difficulties (HP:0002880) | 2.01484911 |
| 72 | Abnormality of the renal medulla (HP:0100957) | 1.97599776 |
| 73 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.96683073 |
| 74 | Abnormality of alanine metabolism (HP:0010916) | 1.96683073 |
| 75 | Hyperalaninemia (HP:0003348) | 1.96683073 |
| 76 | Renal cortical cysts (HP:0000803) | 1.96594130 |
| 77 | Ketosis (HP:0001946) | 1.95948393 |
| 78 | Dyskinesia (HP:0100660) | 1.95372618 |
| 79 | Abnormality of the pons (HP:0007361) | 1.93993838 |
| 80 | Type II lissencephaly (HP:0007260) | 1.92890006 |
| 81 | Abnormality of vitamin B metabolism (HP:0004340) | 1.92837318 |
| 82 | Stenosis of the external auditory canal (HP:0000402) | 1.91806338 |
| 83 | Colon cancer (HP:0003003) | 1.91599982 |
| 84 | Pendular nystagmus (HP:0012043) | 1.90040808 |
| 85 | Sclerocornea (HP:0000647) | 1.88174800 |
| 86 | Abnormal hemoglobin (HP:0011902) | 1.87654698 |
| 87 | Severe combined immunodeficiency (HP:0004430) | 1.87416560 |
| 88 | Abnormality of magnesium homeostasis (HP:0004921) | 1.86123163 |
| 89 | Cystic liver disease (HP:0006706) | 1.85436986 |
| 90 | Constricted visual fields (HP:0001133) | 1.83251145 |
| 91 | Agitation (HP:0000713) | 1.82413079 |
| 92 | CNS demyelination (HP:0007305) | 1.81833820 |
| 93 | Increased IgM level (HP:0003496) | 1.81769010 |
| 94 | Type I transferrin isoform profile (HP:0003642) | 1.80604482 |
| 95 | Polyuria (HP:0000103) | 1.78962060 |
| 96 | Microretrognathia (HP:0000308) | 1.78677768 |
| 97 | Muscle fiber atrophy (HP:0100295) | 1.77911935 |
| 98 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.76471195 |
| 99 | Leukodystrophy (HP:0002415) | 1.76027284 |
| 100 | Reduced antithrombin III activity (HP:0001976) | 1.74737853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.67742006 |
| 2 | BCKDK | 3.31380841 |
| 3 | TLK1 | 3.13201806 |
| 4 | ZAK | 2.66604325 |
| 5 | WNK4 | 2.45801192 |
| 6 | ADRBK2 | 2.41843071 |
| 7 | TIE1 | 2.36307854 |
| 8 | MAP4K2 | 2.16987631 |
| 9 | GRK1 | 2.12657733 |
| 10 | KDR | 2.11522501 |
| 11 | PASK | 2.02370667 |
| 12 | TAOK3 | 1.91288841 |
| 13 | VRK2 | 1.86865225 |
| 14 | NUAK1 | 1.86552368 |
| 15 | CDK19 | 1.77995409 |
| 16 | CAMKK2 | 1.76502550 |
| 17 | PINK1 | 1.75744234 |
| 18 | FRK | 1.69346942 |
| 19 | STK16 | 1.61239083 |
| 20 | STK39 | 1.57494525 |
| 21 | FES | 1.45392015 |
| 22 | WNK3 | 1.39735039 |
| 23 | MAP3K12 | 1.38361898 |
| 24 | TESK2 | 1.37099349 |
| 25 | VRK1 | 1.36300324 |
| 26 | TEC | 1.35259209 |
| 27 | ITK | 1.33727076 |
| 28 | EIF2AK3 | 1.28306682 |
| 29 | LIMK1 | 1.24620692 |
| 30 | PHKG2 | 1.22616070 |
| 31 | PHKG1 | 1.22616070 |
| 32 | NME2 | 1.20637956 |
| 33 | PDK2 | 1.19412516 |
| 34 | MAP2K6 | 1.10952229 |
| 35 | INSRR | 1.09186041 |
| 36 | NME1 | 1.08498848 |
| 37 | BMPR1B | 1.05687086 |
| 38 | SYK | 1.05066329 |
| 39 | CAMKK1 | 1.03702678 |
| 40 | MAP4K1 | 1.03675598 |
| 41 | IKBKB | 1.02968033 |
| 42 | OBSCN | 0.99904680 |
| 43 | GRK6 | 0.98067470 |
| 44 | RPS6KA5 | 0.95869301 |
| 45 | DYRK2 | 0.94946303 |
| 46 | MUSK | 0.94714182 |
| 47 | BTK | 0.94696826 |
| 48 | BUB1 | 0.92996274 |
| 49 | SCYL2 | 0.92570766 |
| 50 | OXSR1 | 0.91894249 |
| 51 | LCK | 0.88835071 |
| 52 | PRKCQ | 0.87261612 |
| 53 | KIT | 0.87087765 |
| 54 | TRIM28 | 0.85624146 |
| 55 | PIK3CG | 0.85421477 |
| 56 | PLK4 | 0.81509858 |
| 57 | DAPK2 | 0.79898041 |
| 58 | PIK3CA | 0.77406889 |
| 59 | EIF2AK1 | 0.76891747 |
| 60 | IKBKE | 0.76462703 |
| 61 | PIM1 | 0.73607271 |
| 62 | MAP2K7 | 0.70660179 |
| 63 | ADRBK1 | 0.70503003 |
| 64 | ABL2 | 0.65162593 |
| 65 | MAP2K2 | 0.61340679 |
| 66 | MAPK13 | 0.60248850 |
| 67 | MAP3K4 | 0.60190600 |
| 68 | WNK1 | 0.59231985 |
| 69 | MAP3K11 | 0.57708120 |
| 70 | CSNK2A1 | 0.56726349 |
| 71 | LYN | 0.55800393 |
| 72 | DAPK1 | 0.55196005 |
| 73 | CSNK2A2 | 0.54351745 |
| 74 | RPS6KA6 | 0.54317990 |
| 75 | PIM2 | 0.54302255 |
| 76 | TNK2 | 0.52272003 |
| 77 | PRKACA | 0.51686921 |
| 78 | GRK7 | 0.50587814 |
| 79 | CAMK1 | 0.50137700 |
| 80 | CSF1R | 0.48612140 |
| 81 | CSNK1G3 | 0.48263763 |
| 82 | PRKCA | 0.48251045 |
| 83 | ATR | 0.47285378 |
| 84 | PRKCG | 0.45537309 |
| 85 | CAMK2A | 0.44460638 |
| 86 | PLK3 | 0.43243179 |
| 87 | PRKCE | 0.41502015 |
| 88 | DAPK3 | 0.40958716 |
| 89 | CDC7 | 0.40429353 |
| 90 | AURKA | 0.40027777 |
| 91 | MYLK | 0.39901133 |
| 92 | RPS6KC1 | 0.39440416 |
| 93 | RPS6KL1 | 0.39440416 |
| 94 | BMPR2 | 0.39070635 |
| 95 | CSNK1G2 | 0.38649266 |
| 96 | IGF1R | 0.38647238 |
| 97 | PRKCD | 0.37236139 |
| 98 | PLK1 | 0.36549526 |
| 99 | CSNK1G1 | 0.36358650 |
| 100 | AURKB | 0.34578505 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.31040278 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.92138312 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.72920494 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.16727384 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.39983822 |
| 6 | Asthma_Homo sapiens_hsa05310 | 2.20845696 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.11550252 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.11316052 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.08322852 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.05180173 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.04831377 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.02167732 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.99254611 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.93046394 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.89646314 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.83739386 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.79432176 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.79136878 |
| 19 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.71807960 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.68338718 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.62268921 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.61624897 |
| 23 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.59013669 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.54658892 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.54341303 |
| 26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.52180059 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.49453646 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.44397710 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.41647878 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.34527629 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.29999791 |
| 32 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.26601895 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.19944600 |
| 34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.10064303 |
| 35 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.09318446 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.05956442 |
| 37 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03999230 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.02971673 |
| 39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.02137469 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.00468644 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.99714101 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.96924705 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.96094254 |
| 44 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.95597213 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.94167554 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.91909642 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.90913380 |
| 48 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.88809608 |
| 49 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.87949673 |
| 50 | Mismatch repair_Homo sapiens_hsa03430 | 0.86689505 |
| 51 | Base excision repair_Homo sapiens_hsa03410 | 0.81235282 |
| 52 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78819211 |
| 53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.78607162 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.76502625 |
| 55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.75867806 |
| 56 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.73791983 |
| 57 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.73452442 |
| 58 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73432623 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73427038 |
| 60 | Spliceosome_Homo sapiens_hsa03040 | 0.70009676 |
| 61 | DNA replication_Homo sapiens_hsa03030 | 0.69934716 |
| 62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.67303912 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65972808 |
| 64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.65364631 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64921630 |
| 66 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.64368340 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.63882122 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63174986 |
| 69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.58961221 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58686922 |
| 71 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.58304114 |
| 72 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58210198 |
| 73 | Nicotine addiction_Homo sapiens_hsa05033 | 0.55649302 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54403805 |
| 75 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.54194778 |
| 76 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.52564747 |
| 77 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.51308866 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51048467 |
| 79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.51015683 |
| 80 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.47832230 |
| 81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.46829176 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46100353 |
| 83 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45524178 |
| 84 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42707366 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42255078 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.38330301 |
| 87 | Viral myocarditis_Homo sapiens_hsa05416 | 0.37820238 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.37666213 |
| 89 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.36980225 |
| 90 | Morphine addiction_Homo sapiens_hsa05032 | 0.35033698 |
| 91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.26370369 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.24627115 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.21939389 |
| 94 | Measles_Homo sapiens_hsa05162 | 0.18569972 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.18492941 |
| 96 | Malaria_Homo sapiens_hsa05144 | 0.18379463 |
| 97 | Mineral absorption_Homo sapiens_hsa04978 | 0.18057654 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.17441155 |
| 99 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.17086128 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16802210 |

