RPL5P30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nephron tubule morphogenesis (GO:0072078)5.40202722
2nephron epithelium morphogenesis (GO:0072088)5.40202722
3DNA deamination (GO:0045006)4.38391921
4water-soluble vitamin biosynthetic process (GO:0042364)4.31114412
5ribosomal small subunit assembly (GO:0000028)4.28677856
6protein complex biogenesis (GO:0070271)4.26777886
7protein neddylation (GO:0045116)4.16152688
8respiratory chain complex IV assembly (GO:0008535)3.95314404
9ribosomal large subunit biogenesis (GO:0042273)3.92933218
10energy coupled proton transport, down electrochemical gradient (GO:0015985)3.91082297
11ATP synthesis coupled proton transport (GO:0015986)3.91082297
12mitochondrial respiratory chain complex assembly (GO:0033108)3.88894807
13translational termination (GO:0006415)3.84385121
14establishment of protein localization to mitochondrial membrane (GO:0090151)3.84192634
15cytochrome complex assembly (GO:0017004)3.82498850
16ribosomal small subunit biogenesis (GO:0042274)3.69189515
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.67712692
18mitochondrial respiratory chain complex I assembly (GO:0032981)3.67712692
19NADH dehydrogenase complex assembly (GO:0010257)3.67712692
20positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.63964401
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.62151317
22renal tubule morphogenesis (GO:0061333)3.62141453
23viral transcription (GO:0019083)3.58558565
24regulation of isotype switching to IgG isotypes (GO:0048302)3.58410876
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.57201333
26protein polyglutamylation (GO:0018095)3.47584069
27SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.45174989
28behavioral response to nicotine (GO:0035095)3.43682597
29regulation of type B pancreatic cell apoptotic process (GO:2000674)3.41347767
30GTP biosynthetic process (GO:0006183)3.40399668
31cellular response to interferon-beta (GO:0035458)3.39422218
32RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.39134800
33tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.39134800
34cotranslational protein targeting to membrane (GO:0006613)3.38663839
35protein targeting to ER (GO:0045047)3.37459023
36mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.37302324
37response to nitrosative stress (GO:0051409)3.36491489
38nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.36137205
39maturation of 5.8S rRNA (GO:0000460)3.33346653
40regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.32447442
41regulation of cilium movement (GO:0003352)3.31019729
42rRNA modification (GO:0000154)3.29255198
43exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.24008414
44establishment of protein localization to endoplasmic reticulum (GO:0072599)3.21820892
45protein localization to endoplasmic reticulum (GO:0070972)3.21748227
46cellular sodium ion homeostasis (GO:0006883)3.21731756
47L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.21589243
48response to pheromone (GO:0019236)3.18393109
49cysteine metabolic process (GO:0006534)3.16580102
50maturation of SSU-rRNA (GO:0030490)3.14496060
51translational elongation (GO:0006414)3.14403460
52signal peptide processing (GO:0006465)3.12137890
53cellular component biogenesis (GO:0044085)3.07296350
54electron transport chain (GO:0022900)3.07220383
55rRNA methylation (GO:0031167)3.06076482
56nucleotide transmembrane transport (GO:1901679)3.05724711
57respiratory electron transport chain (GO:0022904)3.03713597
58axoneme assembly (GO:0035082)2.98279693
59amino acid salvage (GO:0043102)2.96886039
60L-methionine salvage (GO:0071267)2.96886039
61L-methionine biosynthetic process (GO:0071265)2.96886039
62piRNA metabolic process (GO:0034587)2.95499184
63preassembly of GPI anchor in ER membrane (GO:0016254)2.92775455
64epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.88877945
65chaperone-mediated protein transport (GO:0072321)2.85572367
66translation (GO:0006412)2.84281555
67ribonucleoprotein complex biogenesis (GO:0022613)2.80261427
68cellular protein complex disassembly (GO:0043624)2.78616453
69rRNA processing (GO:0006364)2.75358172
70epithelial cilium movement (GO:0003351)2.74374257
71fucose catabolic process (GO:0019317)2.74293414
72L-fucose metabolic process (GO:0042354)2.74293414
73L-fucose catabolic process (GO:0042355)2.74293414
74rRNA metabolic process (GO:0016072)2.72421899
75cellular ketone body metabolic process (GO:0046950)2.71251705
76tRNA processing (GO:0008033)2.70861671
77regulation of immunoglobulin secretion (GO:0051023)2.70771111
78energy homeostasis (GO:0097009)2.70475923
79termination of RNA polymerase III transcription (GO:0006386)2.70339074
80transcription elongation from RNA polymerase III promoter (GO:0006385)2.70339074
81UTP biosynthetic process (GO:0006228)2.69801157
82regulation of regulatory T cell differentiation (GO:0045589)2.67205320
83mannosylation (GO:0097502)2.65549561
84purine nucleotide salvage (GO:0032261)2.62320157
85lens development in camera-type eye (GO:0002088)2.61145433
86proteasome assembly (GO:0043248)2.59264106
87UTP metabolic process (GO:0046051)2.59004369
88translational initiation (GO:0006413)2.55596908
89DNA demethylation (GO:0080111)2.55550073
90viral life cycle (GO:0019058)2.55156580
91regulation of female receptivity (GO:0045924)2.53749044
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.52132799
93purine nucleoside triphosphate biosynthetic process (GO:0009145)2.51828581
94negative regulation of cAMP-mediated signaling (GO:0043951)2.48960513
95renal absorption (GO:0070293)2.48337920
96negative regulation of cell cycle arrest (GO:0071157)2.47576445
97negative regulation of T cell differentiation in thymus (GO:0033085)2.46604970
98GPI anchor metabolic process (GO:0006505)2.44436974
99chemosensory behavior (GO:0007635)2.43546063
100intracellular protein transmembrane import (GO:0044743)2.43409519

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.83884381
2EZH2_22144423_ChIP-Seq_EOC_Human3.85431196
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.57106317
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.23583406
5ZNF274_21170338_ChIP-Seq_K562_Hela2.87201948
6VDR_22108803_ChIP-Seq_LS180_Human2.84322060
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83631143
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.80886544
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.70850794
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.66009383
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.55484316
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.30512662
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.21159407
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.11258925
15VDR_23849224_ChIP-Seq_CD4+_Human2.11211910
16HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.05544673
17PCGF2_27294783_Chip-Seq_ESCs_Mouse1.99307294
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.99044335
19BMI1_23680149_ChIP-Seq_NPCS_Mouse1.92328569
20GBX2_23144817_ChIP-Seq_PC3_Human1.84801440
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82606537
22NOTCH1_21737748_ChIP-Seq_TLL_Human1.75269737
23BP1_19119308_ChIP-ChIP_Hs578T_Human1.74531186
24EWS_26573619_Chip-Seq_HEK293_Human1.73058890
25ELK1_19687146_ChIP-ChIP_HELA_Human1.70121909
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.68620258
27FOXP3_21729870_ChIP-Seq_TREG_Human1.63166862
28FUS_26573619_Chip-Seq_HEK293_Human1.62934277
29MYC_18940864_ChIP-ChIP_HL60_Human1.62109995
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.61402568
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.58711246
32TP53_22573176_ChIP-Seq_HFKS_Human1.52067717
33MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.48846249
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.48126278
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.47593129
36P300_19829295_ChIP-Seq_ESCs_Human1.45656987
37SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39728185
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.39650289
39CREB1_15753290_ChIP-ChIP_HEK293T_Human1.39244324
40IGF1R_20145208_ChIP-Seq_DFB_Human1.38014950
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.32472091
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.29310702
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.27284894
44AR_20517297_ChIP-Seq_VCAP_Human1.24291859
45TAF15_26573619_Chip-Seq_HEK293_Human1.23484259
46FOXA1_27270436_Chip-Seq_PROSTATE_Human1.22003698
47FOXA1_25329375_ChIP-Seq_VCAP_Human1.22003698
48GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20977346
49ETV2_25802403_ChIP-Seq_MESCs_Mouse1.20657909
50BCAT_22108803_ChIP-Seq_LS180_Human1.19307112
51REST_21632747_ChIP-Seq_MESCs_Mouse1.17194002
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16319517
53IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15735462
54CBP_20019798_ChIP-Seq_JUKART_Human1.15735462
55GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.14632418
56GATA3_21878914_ChIP-Seq_MCF-7_Human1.14415367
57SOX2_19829295_ChIP-Seq_ESCs_Human1.13306813
58NANOG_19829295_ChIP-Seq_ESCs_Human1.13306813
59ER_23166858_ChIP-Seq_MCF-7_Human1.13087927
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.13078399
61ELK1_22589737_ChIP-Seq_MCF10A_Human1.11648614
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.11507139
63TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03948418
64TCF4_22108803_ChIP-Seq_LS180_Human1.03716737
65P53_22387025_ChIP-Seq_ESCs_Mouse1.02824272
66CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.02154801
67CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.01797697
68AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00673826
69IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99866164
70RNF2_27304074_Chip-Seq_NSC_Mouse0.99698938
71EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98876379
72MYC_18555785_ChIP-Seq_MESCs_Mouse0.98865423
73NCOR_22424771_ChIP-Seq_293T_Human0.98804638
74TAF2_19829295_ChIP-Seq_ESCs_Human0.98533801
75EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.98475397
76MYC_19829295_ChIP-Seq_ESCs_Human0.97180562
77FOXH1_21741376_ChIP-Seq_EPCs_Human0.96929087
78HOXB7_26014856_ChIP-Seq_BT474_Human0.96662052
79GABP_19822575_ChIP-Seq_HepG2_Human0.96443970
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94260774
81KLF5_20875108_ChIP-Seq_MESCs_Mouse0.93896304
82PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.92027854
83NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.91902086
84CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90537649
85LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89595862
86ERA_21632823_ChIP-Seq_H3396_Human0.88258553
87CRX_20693478_ChIP-Seq_RETINA_Mouse0.88025198
88PADI4_21655091_ChIP-ChIP_MCF-7_Human0.86985600
89OCT4_18555785_Chip-Seq_ESCs_Mouse0.85942088
90RBPJ_21746931_ChIP-Seq_IB4_Human0.85674289
91TTF2_22483619_ChIP-Seq_HELA_Human0.85196502
92GATA3_26560356_Chip-Seq_TH2_Human0.84389171
93SMAD4_21799915_ChIP-Seq_A2780_Human0.83227041
94EZH2_27304074_Chip-Seq_ESCs_Mouse0.83074907
95P53_21459846_ChIP-Seq_SAOS-2_Human0.82505087
96TCF4_23295773_ChIP-Seq_U87_Human0.82417935
97PIAS1_25552417_ChIP-Seq_VCAP_Human0.82149501
98FOXA1_21572438_ChIP-Seq_LNCaP_Human0.81599345
99NANOG_18555785_Chip-Seq_ESCs_Mouse0.81439875
100STAT3_18555785_Chip-Seq_ESCs_Mouse0.81429362

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006072_abnormal_retinal_apoptosis3.33635928
2MP0009379_abnormal_foot_pigmentation3.31694333
3MP0002876_abnormal_thyroid_physiology3.23573555
4MP0008877_abnormal_DNA_methylation3.05732349
5MP0004885_abnormal_endolymph2.93822293
6MP0002837_dystrophic_cardiac_calcinosis2.29522598
7MP0006292_abnormal_olfactory_placode2.26529175
8MP0002736_abnormal_nociception_after2.21450917
9MP0001968_abnormal_touch/_nociception2.15355480
10MP0003646_muscle_fatigue2.13525136
11MP0003787_abnormal_imprinting2.08684990
12MP0004145_abnormal_muscle_electrophysio2.03948056
13MP0002102_abnormal_ear_morphology2.03680430
14MP0005645_abnormal_hypothalamus_physiol2.03513261
15MP0005551_abnormal_eye_electrophysiolog1.96225142
16MP0004142_abnormal_muscle_tone1.94692166
17MP0002822_catalepsy1.88051056
18MP0008872_abnormal_physiological_respon1.83806612
19MP0003195_calcinosis1.80792371
20MP0000631_abnormal_neuroendocrine_gland1.78524695
21MP0004147_increased_porphyrin_level1.76677113
22MP0008789_abnormal_olfactory_epithelium1.76241109
23MP0002735_abnormal_chemical_nociception1.76136738
24MP0006276_abnormal_autonomic_nervous1.73069648
25MP0004043_abnormal_pH_regulation1.69163973
26MP0001873_stomach_inflammation1.65666384
27MP0002272_abnormal_nervous_system1.64627024
28MP0005253_abnormal_eye_physiology1.58428483
29MP0008058_abnormal_DNA_repair1.58132941
30MP0008875_abnormal_xenobiotic_pharmacok1.56736557
31MP0003186_abnormal_redox_activity1.56384548
32MP0001529_abnormal_vocalization1.52332037
33MP0003938_abnormal_ear_development1.48287019
34MP0002163_abnormal_gland_morphology1.46632850
35MP0002138_abnormal_hepatobiliary_system1.41840665
36MP0001188_hyperpigmentation1.39429559
37MP0005646_abnormal_pituitary_gland1.38615475
38MP0002572_abnormal_emotion/affect_behav1.38302012
39MP0001986_abnormal_taste_sensitivity1.37287173
40MP0003137_abnormal_impulse_conducting1.35907427
41MP0009745_abnormal_behavioral_response1.35054421
42MP0002234_abnormal_pharynx_morphology1.34856636
43MP0000427_abnormal_hair_cycle1.32362100
44MP0003718_maternal_effect1.31094212
45MP0001905_abnormal_dopamine_level1.30305483
46MP0005075_abnormal_melanosome_morpholog1.30227627
47MP0003122_maternal_imprinting1.28717848
48MP0002557_abnormal_social/conspecific_i1.28682135
49MP0001835_abnormal_antigen_presentation1.24827232
50MP0003567_abnormal_fetal_cardiomyocyte1.24711045
51MP0005499_abnormal_olfactory_system1.24244120
52MP0005394_taste/olfaction_phenotype1.24244120
53MP0001293_anophthalmia1.22799745
54MP0001970_abnormal_pain_threshold1.22395381
55MP0009780_abnormal_chondrocyte_physiolo1.21135347
56MP0002184_abnormal_innervation1.19864235
57MP0001919_abnormal_reproductive_system1.18785469
58MP0003880_abnormal_central_pattern1.18635501
59MP0003011_delayed_dark_adaptation1.16602484
60MP0003786_premature_aging1.15490509
61MP0002063_abnormal_learning/memory/cond1.15426673
62MP0005389_reproductive_system_phenotype1.14484227
63MP0002160_abnormal_reproductive_system1.14309907
64MP0003879_abnormal_hair_cell1.13174346
65MP0005379_endocrine/exocrine_gland_phen1.12068902
66MP0001501_abnormal_sleep_pattern1.08760849
67MP0002733_abnormal_thermal_nociception1.06653163
68MP0004924_abnormal_behavior1.06064464
69MP0005386_behavior/neurological_phenoty1.06064464
70MP0005671_abnormal_response_to1.03313014
71MP0001765_abnormal_ion_homeostasis1.02900051
72MP0005084_abnormal_gallbladder_morpholo1.02300556
73MP0002693_abnormal_pancreas_physiology1.01369715
74MP0002938_white_spotting1.00631384
75MP0003121_genomic_imprinting1.00579503
76MP0005195_abnormal_posterior_eye0.99608774
77MP0005636_abnormal_mineral_homeostasis0.98023396
78MP0008775_abnormal_heart_ventricle0.96902890
79MP0002148_abnormal_hypersensitivity_rea0.96783994
80MP0009046_muscle_twitch0.91404125
81MP0005332_abnormal_amino_acid0.90487545
82MP0001984_abnormal_olfaction0.89412740
83MP0002067_abnormal_sensory_capabilities0.89281858
84MP0004133_heterotaxia0.86274620
85MP0000685_abnormal_immune_system0.85747501
86MP0001485_abnormal_pinna_reflex0.81873830
87MP0004215_abnormal_myocardial_fiber0.80897954
88MP0000026_abnormal_inner_ear0.79970079
89MP0001486_abnormal_startle_reflex0.78499426
90MP0002752_abnormal_somatic_nervous0.77555509
91MP0003635_abnormal_synaptic_transmissio0.76859513
92MP0001440_abnormal_grooming_behavior0.72635075
93MP0001944_abnormal_pancreas_morphology0.72544614
94MP0003638_abnormal_response/metabolism_0.71688862
95MP0003183_abnormal_peptide_metabolism0.70940708
96MP0008995_early_reproductive_senescence0.70604184
97MP0006036_abnormal_mitochondrial_physio0.67399881
98MP0003633_abnormal_nervous_system0.66681637
99MP0004742_abnormal_vestibular_system0.66380747
100MP0003937_abnormal_limbs/digits/tail_de0.66297083

Predicted human phenotypes

RankGene SetZ-score
1Increased circulating renin level (HP:0000848)6.26132973
2Decreased circulating renin level (HP:0003351)5.69490766
3Hyperactive renin-angiotensin system (HP:0000841)5.06448312
4Hyperkalemia (HP:0002153)4.95363240
5Colon cancer (HP:0003003)3.95530376
6Absent rod-and cone-mediated responses on ERG (HP:0007688)3.84612777
7Acute necrotizing encephalopathy (HP:0006965)3.48658823
8Mitochondrial inheritance (HP:0001427)3.31756986
9Abnormality of renin-angiotensin system (HP:0000847)3.30607459
10Increased CSF lactate (HP:0002490)3.20008282
11Absent/shortened dynein arms (HP:0200106)3.17168780
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.17168780
13Acute encephalopathy (HP:0006846)3.12621760
14Hyperaldosteronism (HP:0000859)3.07294364
15Abnormal rod and cone electroretinograms (HP:0008323)3.07151747
16Increased hepatocellular lipid droplets (HP:0006565)3.05990867
17Toxemia of pregnancy (HP:0100603)3.05882345
18Pancreatic fibrosis (HP:0100732)3.05651659
19Pancreatic cysts (HP:0001737)3.03557655
20Abnormality of midbrain morphology (HP:0002418)3.00698923
21Molar tooth sign on MRI (HP:0002419)3.00698923
22Abnormal mitochondria in muscle tissue (HP:0008316)2.94640834
23Abnormality of potassium homeostasis (HP:0011042)2.94537014
24Severe visual impairment (HP:0001141)2.90638696
25Lipid accumulation in hepatocytes (HP:0006561)2.89623738
26Pendular nystagmus (HP:0012043)2.86770501
273-Methylglutaconic aciduria (HP:0003535)2.83142337
28Progressive macrocephaly (HP:0004481)2.82506314
29Renal Fanconi syndrome (HP:0001994)2.66430512
30Hepatocellular necrosis (HP:0001404)2.65605589
31Increased corneal curvature (HP:0100692)2.61476917
32Keratoconus (HP:0000563)2.61476917
33Nephronophthisis (HP:0000090)2.59625326
34Methylmalonic acidemia (HP:0002912)2.57237271
35Intestinal atresia (HP:0011100)2.55886013
36Abolished electroretinogram (ERG) (HP:0000550)2.52659471
37Type II lissencephaly (HP:0007260)2.49016190
38Abnormality of cells of the erythroid lineage (HP:0012130)2.45814265
39Abnormal respiratory motile cilium morphology (HP:0005938)2.41795244
40Abnormal respiratory epithelium morphology (HP:0012253)2.41795244
41Severe combined immunodeficiency (HP:0004430)2.41413031
42Hepatic necrosis (HP:0002605)2.32609566
43Double outlet right ventricle (HP:0001719)2.31855996
44Congenital malformation of the right heart (HP:0011723)2.31855996
45Abnormality of chloride homeostasis (HP:0011422)2.27644883
46Oligodactyly (hands) (HP:0001180)2.27350741
47Abnormality of DNA repair (HP:0003254)2.26988059
48Congenital stationary night blindness (HP:0007642)2.25340795
49Methylmalonic aciduria (HP:0012120)2.24109894
50True hermaphroditism (HP:0010459)2.21480323
51Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.19735677
52Optic disc pallor (HP:0000543)2.18776236
53Abnormal number of erythroid precursors (HP:0012131)2.18736415
54Nuclear cataract (HP:0100018)2.18696658
55Decreased central vision (HP:0007663)2.17240604
56Aplasia/Hypoplasia of the spleen (HP:0010451)2.16472311
57Macrocytic anemia (HP:0001972)2.16007328
58Reticulocytopenia (HP:0001896)2.15989407
59Stomatitis (HP:0010280)2.15822807
60Papilledema (HP:0001085)2.15365571
61Attenuation of retinal blood vessels (HP:0007843)2.14864503
62Increased serum lactate (HP:0002151)2.12955601
63Abnormality of the labia minora (HP:0012880)2.12243563
64Asplenia (HP:0001746)2.04676863
65Abnormality of renal resorption (HP:0011038)2.01491048
66Abnormality of the renal medulla (HP:0100957)1.99028255
67Cerebral edema (HP:0002181)1.98280014
68Thyroiditis (HP:0100646)1.97404595
69Exertional dyspnea (HP:0002875)1.93828930
70Testicular atrophy (HP:0000029)1.93565239
71Abnormal ciliary motility (HP:0012262)1.93552631
72Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.93517102
73Hyperglycinemia (HP:0002154)1.92852629
74Hypoplastic pelvis (HP:0008839)1.89284605
75Lactic acidosis (HP:0003128)1.88610710
76Abnormal respiratory motile cilium physiology (HP:0012261)1.87471085
77Abnormal albumin level (HP:0012116)1.87093685
78Hypoalbuminemia (HP:0003073)1.87093685
79Agitation (HP:0000713)1.86581484
80Hyponatremia (HP:0002902)1.86058098
81Optic nerve hypoplasia (HP:0000609)1.85978879
82Increased intramyocellular lipid droplets (HP:0012240)1.85589103
83Cystic liver disease (HP:0006706)1.84260123
84Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84035913
85Aplasia/hypoplasia of the uterus (HP:0008684)1.83967067
86Abnormality of the renal cortex (HP:0011035)1.81943535
87Abnormality of alanine metabolism (HP:0010916)1.81534999
88Hyperalaninemia (HP:0003348)1.81534999
89Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.81534999
90Anencephaly (HP:0002323)1.78934959
91Medial flaring of the eyebrow (HP:0010747)1.77532089
92Deep palmar crease (HP:0006191)1.76173127
93Thyroid-stimulating hormone excess (HP:0002925)1.75428201
94Rib fusion (HP:0000902)1.72472163
95IgG deficiency (HP:0004315)1.71604751
96Abnormal number of incisors (HP:0011064)1.71407464
97Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71348260
98Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71348260
99Congenital, generalized hypertrichosis (HP:0004540)1.64861224
100Combined immunodeficiency (HP:0005387)1.64484877

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.03530384
2MAP2K63.80560078
3TXK2.96820799
4WNK42.77767487
5IRAK42.69341387
6TNIK2.40503798
7ADRBK22.36789219
8GRK12.28990578
9TAOK32.23563704
10NME12.10347495
11NUAK12.03257009
12STK161.99075918
13PDK21.88401028
14TLK11.83411194
15WNK31.80605051
16ZAK1.79649228
17DYRK21.66864123
18MST41.58203862
19TAF11.53597944
20NLK1.52148218
21DAPK21.51099601
22FRK1.47847582
23BMPR1B1.44932526
24EIF2AK31.44289084
25TIE11.42565488
26PASK1.42402605
27TEC1.40788576
28CDK191.38613185
29ITK1.37425052
30OXSR11.33077754
31STK391.33007625
32PHKG21.31445910
33PHKG11.31445910
34MAP3K41.29953133
35MKNK11.22682845
36VRK21.12710394
37NTRK31.10817325
38PRKCG1.08380679
39PINK11.07052699
40MAP2K21.07036194
41BCKDK1.04218963
42EIF2AK11.03495926
43MKNK21.00555867
44NME21.00330901
45TSSK60.97983631
46FES0.94187686
47MARK10.93801074
48INSRR0.92263643
49MAP4K10.90333284
50TRIM280.84809411
51KIT0.83359062
52EIF2AK20.81132740
53MAPK130.79316858
54PAK30.76508989
55MAP3K120.74519123
56PRKCQ0.72030291
57RPS6KA50.71036200
58ALK0.70514135
59PLK20.69183807
60PLK40.68004771
61CDC70.67641364
62VRK10.66810052
63IKBKB0.63433898
64SGK10.62798160
65CAMK10.60283847
66STK110.60250291
67BUB10.59664290
68CAMKK10.59014494
69WNK10.58996308
70OBSCN0.58422980
71CSNK1G20.56671556
72CSNK1G30.56064922
73JAK30.54795419
74SYK0.54339049
75MAP4K20.54328424
76CAMKK20.53811868
77PRKCI0.53397301
78PRKACA0.50329077
79RPS6KA40.49583053
80CSNK2A20.48672297
81PBK0.47866968
82BTK0.44993871
83MAP3K90.44881036
84MAPKAPK50.41930127
85LCK0.41378957
86CSNK1G10.40630468
87PRKCE0.40088143
88CSNK1A10.39738311
89PIK3CG0.39563432
90NTRK20.39500738
91PIK3CA0.39365701
92CSNK1E0.38523986
93RPS6KA60.37553861
94ATR0.37098599
95IGF1R0.36934124
96CAMK2A0.36879531
97DAPK10.36079730
98PRKCA0.34354271
99CSNK1A1L0.33920354
100LYN0.33631930

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.91590341
2Oxidative phosphorylation_Homo sapiens_hsa001903.59181058
3Protein export_Homo sapiens_hsa030603.22528312
4Parkinsons disease_Homo sapiens_hsa050122.79416685
5Proteasome_Homo sapiens_hsa030502.62946414
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.44120465
7RNA polymerase_Homo sapiens_hsa030202.36777975
8Asthma_Homo sapiens_hsa053102.32507709
9Alzheimers disease_Homo sapiens_hsa050102.02912304
10Basal transcription factors_Homo sapiens_hsa030222.02669697
11Huntingtons disease_Homo sapiens_hsa050161.90996039
12RNA degradation_Homo sapiens_hsa030181.90102645
13Allograft rejection_Homo sapiens_hsa053301.89365434
14Autoimmune thyroid disease_Homo sapiens_hsa053201.84785939
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.83555463
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.80500341
17Type I diabetes mellitus_Homo sapiens_hsa049401.80314845
18Cardiac muscle contraction_Homo sapiens_hsa042601.78291904
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.73875390
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.73475318
21Linoleic acid metabolism_Homo sapiens_hsa005911.69628241
22Nitrogen metabolism_Homo sapiens_hsa009101.65099719
23Nucleotide excision repair_Homo sapiens_hsa034201.59245219
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58978750
25Primary immunodeficiency_Homo sapiens_hsa053401.55608918
26Homologous recombination_Homo sapiens_hsa034401.44812968
27One carbon pool by folate_Homo sapiens_hsa006701.42906110
28Maturity onset diabetes of the young_Homo sapiens_hsa049501.40905749
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.38381037
30Phototransduction_Homo sapiens_hsa047441.32298571
31Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.31763489
32Graft-versus-host disease_Homo sapiens_hsa053321.31416732
33Sulfur metabolism_Homo sapiens_hsa009201.30617772
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28621780
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.28044808
36Propanoate metabolism_Homo sapiens_hsa006401.24057046
37Fanconi anemia pathway_Homo sapiens_hsa034601.23945974
38Nicotine addiction_Homo sapiens_hsa050331.19207774
39Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.17678706
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.11291907
41Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08598534
42RNA transport_Homo sapiens_hsa030131.07572125
43Purine metabolism_Homo sapiens_hsa002301.06156964
44Peroxisome_Homo sapiens_hsa041461.02111108
45Pyrimidine metabolism_Homo sapiens_hsa002400.98492387
46Cysteine and methionine metabolism_Homo sapiens_hsa002700.96487529
47Butanoate metabolism_Homo sapiens_hsa006500.96386427
48Mismatch repair_Homo sapiens_hsa034300.95938446
49Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89455193
50Morphine addiction_Homo sapiens_hsa050320.88985418
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.88118981
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87373065
53Ether lipid metabolism_Homo sapiens_hsa005650.81162388
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.80307105
55Retinol metabolism_Homo sapiens_hsa008300.79838725
56Rheumatoid arthritis_Homo sapiens_hsa053230.78053169
57Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.76803577
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.74021351
59Pentose and glucuronate interconversions_Homo sapiens_hsa000400.73084486
60Chemical carcinogenesis_Homo sapiens_hsa052040.72293415
61Olfactory transduction_Homo sapiens_hsa047400.71226426
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70509945
63Hematopoietic cell lineage_Homo sapiens_hsa046400.69598940
64Base excision repair_Homo sapiens_hsa034100.67712678
65Selenocompound metabolism_Homo sapiens_hsa004500.67625983
66Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.67301935
67Metabolic pathways_Homo sapiens_hsa011000.66064171
68Regulation of autophagy_Homo sapiens_hsa041400.65493322
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65445976
70Tryptophan metabolism_Homo sapiens_hsa003800.65271824
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.65145333
72Serotonergic synapse_Homo sapiens_hsa047260.61283102
73T cell receptor signaling pathway_Homo sapiens_hsa046600.60191005
74GABAergic synapse_Homo sapiens_hsa047270.57398989
75Arachidonic acid metabolism_Homo sapiens_hsa005900.56334339
76DNA replication_Homo sapiens_hsa030300.53418573
77Collecting duct acid secretion_Homo sapiens_hsa049660.52032221
78Circadian entrainment_Homo sapiens_hsa047130.51498273
79Insulin secretion_Homo sapiens_hsa049110.49811659
80Taste transduction_Homo sapiens_hsa047420.48852423
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46714498
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44815065
83Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.44500792
84ABC transporters_Homo sapiens_hsa020100.44015952
85Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.43188699
86Caffeine metabolism_Homo sapiens_hsa002320.42792756
87Antigen processing and presentation_Homo sapiens_hsa046120.42629892
88Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.42120027
89Fat digestion and absorption_Homo sapiens_hsa049750.40195856
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.39425283
91Glutamatergic synapse_Homo sapiens_hsa047240.39052594
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38499414
93Glutathione metabolism_Homo sapiens_hsa004800.38162589
94Ovarian steroidogenesis_Homo sapiens_hsa049130.37829882
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.34279722
96Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33628361
97Salivary secretion_Homo sapiens_hsa049700.33364407
98Steroid biosynthesis_Homo sapiens_hsa001000.32756225
99Sulfur relay system_Homo sapiens_hsa041220.32052360
100Circadian rhythm_Homo sapiens_hsa047100.31974737

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »