

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.80558021 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.80558021 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.63000848 |
| 4 | response to pheromone (GO:0019236) | 5.46539706 |
| 5 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.76860868 |
| 6 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.76860868 |
| 7 | NADH dehydrogenase complex assembly (GO:0010257) | 4.76860868 |
| 8 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.62655348 |
| 9 | protein neddylation (GO:0045116) | 4.52123633 |
| 10 | protein complex biogenesis (GO:0070271) | 4.50378339 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.30775068 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 4.25085668 |
| 13 | respiratory electron transport chain (GO:0022904) | 4.24619827 |
| 14 | electron transport chain (GO:0022900) | 4.23490638 |
| 15 | secondary metabolite biosynthetic process (GO:0044550) | 4.13186271 |
| 16 | melanin biosynthetic process (GO:0042438) | 4.12996278 |
| 17 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.12154172 |
| 18 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.01009901 |
| 19 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.01009901 |
| 20 | behavioral response to nicotine (GO:0035095) | 3.99467890 |
| 21 | protein polyglutamylation (GO:0018095) | 3.94037591 |
| 22 | melanin metabolic process (GO:0006582) | 3.73987159 |
| 23 | piRNA metabolic process (GO:0034587) | 3.71873377 |
| 24 | viral transcription (GO:0019083) | 3.68811782 |
| 25 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.63458257 |
| 26 | translational termination (GO:0006415) | 3.62296342 |
| 27 | ribosomal small subunit assembly (GO:0000028) | 3.61903879 |
| 28 | epithelial cilium movement (GO:0003351) | 3.59132482 |
| 29 | ribosomal large subunit biogenesis (GO:0042273) | 3.58809425 |
| 30 | regulation of cellular respiration (GO:0043457) | 3.52215378 |
| 31 | regulation of cilium movement (GO:0003352) | 3.50882461 |
| 32 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.49512287 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.49512287 |
| 34 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.48489503 |
| 35 | ATP biosynthetic process (GO:0006754) | 3.44095309 |
| 36 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.39770739 |
| 37 | hydrogen ion transmembrane transport (GO:1902600) | 3.37552951 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 3.35971644 |
| 39 | protein targeting to ER (GO:0045047) | 3.34828232 |
| 40 | proton transport (GO:0015992) | 3.28034392 |
| 41 | DNA deamination (GO:0045006) | 3.26467497 |
| 42 | hydrogen transport (GO:0006818) | 3.22800270 |
| 43 | ketone body metabolic process (GO:1902224) | 3.19838943 |
| 44 | platelet dense granule organization (GO:0060155) | 3.17707583 |
| 45 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.17406171 |
| 46 | negative regulation of heart rate (GO:0010459) | 3.17272584 |
| 47 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.17066961 |
| 48 | protein localization to endoplasmic reticulum (GO:0070972) | 3.16819331 |
| 49 | kynurenine metabolic process (GO:0070189) | 3.12887526 |
| 50 | indolalkylamine metabolic process (GO:0006586) | 3.12734384 |
| 51 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.12167988 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.11803905 |
| 53 | inositol phosphate catabolic process (GO:0071545) | 3.10672920 |
| 54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.10250835 |
| 55 | response to redox state (GO:0051775) | 3.09084907 |
| 56 | aldehyde catabolic process (GO:0046185) | 3.02886684 |
| 57 | DNA methylation involved in gamete generation (GO:0043046) | 3.02656005 |
| 58 | acrosome reaction (GO:0007340) | 2.97286987 |
| 59 | translational elongation (GO:0006414) | 2.96369871 |
| 60 | fucose catabolic process (GO:0019317) | 2.94607296 |
| 61 | L-fucose metabolic process (GO:0042354) | 2.94607296 |
| 62 | L-fucose catabolic process (GO:0042355) | 2.94607296 |
| 63 | positive regulation of protein homodimerization activity (GO:0090073) | 2.89046896 |
| 64 | cellular ketone body metabolic process (GO:0046950) | 2.86101956 |
| 65 | regulation of microtubule-based movement (GO:0060632) | 2.83893550 |
| 66 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.81960069 |
| 67 | synaptic transmission, cholinergic (GO:0007271) | 2.81322838 |
| 68 | glycerophospholipid catabolic process (GO:0046475) | 2.81253338 |
| 69 | tryptophan metabolic process (GO:0006568) | 2.81001978 |
| 70 | rRNA modification (GO:0000154) | 2.79981072 |
| 71 | cellular component biogenesis (GO:0044085) | 2.77934603 |
| 72 | indole-containing compound catabolic process (GO:0042436) | 2.77241502 |
| 73 | indolalkylamine catabolic process (GO:0046218) | 2.77241502 |
| 74 | tryptophan catabolic process (GO:0006569) | 2.77241502 |
| 75 | cellular protein complex disassembly (GO:0043624) | 2.76169891 |
| 76 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.75404328 |
| 77 | inositol phosphate dephosphorylation (GO:0046855) | 2.75404328 |
| 78 | sperm motility (GO:0030317) | 2.75272314 |
| 79 | negative regulation of mast cell activation (GO:0033004) | 2.74880503 |
| 80 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.73724253 |
| 81 | maturation of SSU-rRNA (GO:0030490) | 2.73315216 |
| 82 | respiratory chain complex IV assembly (GO:0008535) | 2.72306791 |
| 83 | viral life cycle (GO:0019058) | 2.68150277 |
| 84 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.67613886 |
| 85 | polyol catabolic process (GO:0046174) | 2.65884239 |
| 86 | multicellular organism reproduction (GO:0032504) | 2.63337132 |
| 87 | tRNA processing (GO:0008033) | 2.63026717 |
| 88 | GPI anchor metabolic process (GO:0006505) | 2.62281563 |
| 89 | nonmotile primary cilium assembly (GO:0035058) | 2.59407144 |
| 90 | GPI anchor biosynthetic process (GO:0006506) | 2.58738559 |
| 91 | rRNA catabolic process (GO:0016075) | 2.58438108 |
| 92 | translation (GO:0006412) | 2.57200007 |
| 93 | maturation of 5.8S rRNA (GO:0000460) | 2.57125922 |
| 94 | cilium movement (GO:0003341) | 2.55911560 |
| 95 | regulation of mitochondrial translation (GO:0070129) | 2.55191067 |
| 96 | axonemal dynein complex assembly (GO:0070286) | 2.52536112 |
| 97 | intracellular protein transmembrane import (GO:0044743) | 2.51198960 |
| 98 | anterograde synaptic vesicle transport (GO:0048490) | 2.50721733 |
| 99 | axoneme assembly (GO:0035082) | 2.49958030 |
| 100 | anterograde axon cargo transport (GO:0008089) | 2.48878585 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.67585077 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.33522037 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.31406808 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.22482795 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.05620639 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.03880128 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.01308796 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.73856945 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.60865526 |
| 10 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.55837783 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.48124083 |
| 12 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.44978530 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.06011929 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.02596283 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.93296285 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89594609 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.86926518 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.86314921 |
| 19 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.85450517 |
| 20 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.80369159 |
| 21 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.80214790 |
| 22 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.74926718 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.74274771 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.67371200 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61983001 |
| 26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.57435789 |
| 27 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.56609275 |
| 28 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.54709539 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.53252178 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.52823536 |
| 31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.52025565 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.51954057 |
| 33 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.50666872 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.50070257 |
| 35 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.50042794 |
| 36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.47659624 |
| 37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.43137934 |
| 38 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.42137452 |
| 39 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.41622425 |
| 40 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.41246478 |
| 41 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.40664101 |
| 42 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.40664101 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.37255936 |
| 44 | NCOR_22424771_ChIP-Seq_293T_Human | 1.37043419 |
| 45 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.34547745 |
| 46 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.34004769 |
| 47 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.33900378 |
| 48 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.33013991 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.32963702 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.32963702 |
| 51 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31974134 |
| 52 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.31827540 |
| 53 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.31361667 |
| 54 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.29388869 |
| 55 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.28324627 |
| 56 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.26669669 |
| 57 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.26215814 |
| 58 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26215814 |
| 59 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.25651289 |
| 60 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25107578 |
| 61 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.22506648 |
| 62 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21531507 |
| 63 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21531507 |
| 64 | ERA_21632823_ChIP-Seq_H3396_Human | 1.19976466 |
| 65 | AR_20517297_ChIP-Seq_VCAP_Human | 1.19945327 |
| 66 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.17499070 |
| 67 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.17336989 |
| 68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13763903 |
| 69 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.13020433 |
| 70 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.12336703 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11366501 |
| 72 | AR_25329375_ChIP-Seq_VCAP_Human | 1.10346058 |
| 73 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.10109938 |
| 74 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.10013413 |
| 75 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.09008622 |
| 76 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.08921490 |
| 77 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.08594457 |
| 78 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.08545225 |
| 79 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.07960546 |
| 80 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.07495105 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.06218847 |
| 82 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.05669415 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.05633511 |
| 84 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03199383 |
| 85 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.98549436 |
| 86 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.97448551 |
| 87 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.97387861 |
| 88 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.97063826 |
| 89 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.95695322 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94137202 |
| 91 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.93124987 |
| 92 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.91106451 |
| 93 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.90638758 |
| 94 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89993263 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.89420990 |
| 96 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.88488402 |
| 97 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.88273651 |
| 98 | JUN_21703547_ChIP-Seq_K562_Human | 0.88273362 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86853640 |
| 100 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.86254279 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 5.06964152 |
| 2 | MP0003136_yellow_coat_color | 4.12665768 |
| 3 | MP0006292_abnormal_olfactory_placode | 2.88113767 |
| 4 | MP0003878_abnormal_ear_physiology | 2.52249095 |
| 5 | MP0005377_hearing/vestibular/ear_phenot | 2.52249095 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.38827830 |
| 7 | MP0004885_abnormal_endolymph | 2.35495793 |
| 8 | MP0004142_abnormal_muscle_tone | 2.22625204 |
| 9 | MP0003646_muscle_fatigue | 2.22240504 |
| 10 | MP0004147_increased_porphyrin_level | 2.21481153 |
| 11 | MP0005171_absent_coat_pigmentation | 2.18742923 |
| 12 | MP0003787_abnormal_imprinting | 2.00778835 |
| 13 | MP0009379_abnormal_foot_pigmentation | 1.99333131 |
| 14 | MP0005551_abnormal_eye_electrophysiolog | 1.96626553 |
| 15 | MP0001485_abnormal_pinna_reflex | 1.93935560 |
| 16 | MP0002102_abnormal_ear_morphology | 1.89192916 |
| 17 | MP0005075_abnormal_melanosome_morpholog | 1.88142215 |
| 18 | MP0002095_abnormal_skin_pigmentation | 1.85683202 |
| 19 | MP0008872_abnormal_physiological_respon | 1.84005264 |
| 20 | MP0003186_abnormal_redox_activity | 1.78107979 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.77359391 |
| 22 | MP0005410_abnormal_fertilization | 1.73746189 |
| 23 | MP0002163_abnormal_gland_morphology | 1.71954941 |
| 24 | MP0003011_delayed_dark_adaptation | 1.61382695 |
| 25 | MP0002638_abnormal_pupillary_reflex | 1.57794522 |
| 26 | MP0002938_white_spotting | 1.57319636 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.57068443 |
| 28 | MP0008875_abnormal_xenobiotic_pharmacok | 1.56947825 |
| 29 | MP0001835_abnormal_antigen_presentation | 1.54817053 |
| 30 | MP0005253_abnormal_eye_physiology | 1.52570307 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.49783161 |
| 32 | MP0005423_abnormal_somatic_nervous | 1.49541588 |
| 33 | MP0006072_abnormal_retinal_apoptosis | 1.49539065 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.46896899 |
| 35 | MP0009745_abnormal_behavioral_response | 1.44249322 |
| 36 | MP0005379_endocrine/exocrine_gland_phen | 1.43234420 |
| 37 | MP0002272_abnormal_nervous_system | 1.41468573 |
| 38 | MP0005408_hypopigmentation | 1.39387870 |
| 39 | MP0001486_abnormal_startle_reflex | 1.38564354 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.38377604 |
| 41 | MP0000015_abnormal_ear_pigmentation | 1.37555776 |
| 42 | MP0002837_dystrophic_cardiac_calcinosis | 1.36680673 |
| 43 | MP0001984_abnormal_olfaction | 1.35239176 |
| 44 | MP0002736_abnormal_nociception_after | 1.34885903 |
| 45 | MP0004145_abnormal_muscle_electrophysio | 1.30612921 |
| 46 | MP0001905_abnormal_dopamine_level | 1.30138833 |
| 47 | MP0002735_abnormal_chemical_nociception | 1.26569582 |
| 48 | MP0003880_abnormal_central_pattern | 1.26128502 |
| 49 | MP0000371_diluted_coat_color | 1.20164777 |
| 50 | MP0004742_abnormal_vestibular_system | 1.19503551 |
| 51 | MP0003195_calcinosis | 1.18355505 |
| 52 | MP0001970_abnormal_pain_threshold | 1.16386860 |
| 53 | MP0006036_abnormal_mitochondrial_physio | 1.14756687 |
| 54 | MP0001986_abnormal_taste_sensitivity | 1.12775193 |
| 55 | MP0004043_abnormal_pH_regulation | 1.11923238 |
| 56 | MP0008789_abnormal_olfactory_epithelium | 1.10759933 |
| 57 | MP0002653_abnormal_ependyma_morphology | 1.09508233 |
| 58 | MP0002557_abnormal_social/conspecific_i | 1.07585115 |
| 59 | MP0005670_abnormal_white_adipose | 1.07535893 |
| 60 | MP0002572_abnormal_emotion/affect_behav | 1.06393380 |
| 61 | MP0001324_abnormal_eye_pigmentation | 1.02974226 |
| 62 | MP0001440_abnormal_grooming_behavior | 1.02953082 |
| 63 | MP0000230_abnormal_systemic_arterial | 1.02566529 |
| 64 | MP0006276_abnormal_autonomic_nervous | 1.01935378 |
| 65 | MP0005671_abnormal_response_to | 1.00146365 |
| 66 | MP0009046_muscle_twitch | 0.99040063 |
| 67 | MP0005332_abnormal_amino_acid | 0.98949800 |
| 68 | MP0008995_early_reproductive_senescence | 0.98114327 |
| 69 | MP0001919_abnormal_reproductive_system | 0.93627697 |
| 70 | MP0004133_heterotaxia | 0.93368427 |
| 71 | MP0004381_abnormal_hair_follicle | 0.93194972 |
| 72 | MP0005174_abnormal_tail_pigmentation | 0.92043840 |
| 73 | MP0003718_maternal_effect | 0.90478657 |
| 74 | MP0002876_abnormal_thyroid_physiology | 0.89873465 |
| 75 | MP0001963_abnormal_hearing_physiology | 0.88820140 |
| 76 | MP0002067_abnormal_sensory_capabilities | 0.88335914 |
| 77 | MP0002064_seizures | 0.87157340 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 0.86365143 |
| 79 | MP0005389_reproductive_system_phenotype | 0.86006077 |
| 80 | MP0001293_anophthalmia | 0.85283442 |
| 81 | MP0001502_abnormal_circadian_rhythm | 0.85143811 |
| 82 | MP0008775_abnormal_heart_ventricle | 0.84691064 |
| 83 | MP0005195_abnormal_posterior_eye | 0.84472354 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.84050144 |
| 85 | MP0001529_abnormal_vocalization | 0.82721609 |
| 86 | MP0002752_abnormal_somatic_nervous | 0.81334877 |
| 87 | MP0001929_abnormal_gametogenesis | 0.81313122 |
| 88 | MP0003786_premature_aging | 0.81312189 |
| 89 | MP0009764_decreased_sensitivity_to | 0.80930661 |
| 90 | MP0003122_maternal_imprinting | 0.80094735 |
| 91 | MP0003698_abnormal_male_reproductive | 0.78856825 |
| 92 | MP0002229_neurodegeneration | 0.78333238 |
| 93 | MP0003121_genomic_imprinting | 0.77827950 |
| 94 | MP0005636_abnormal_mineral_homeostasis | 0.76746231 |
| 95 | MP0002733_abnormal_thermal_nociception | 0.76286297 |
| 96 | MP0003693_abnormal_embryo_hatching | 0.75736004 |
| 97 | MP0005394_taste/olfaction_phenotype | 0.73345088 |
| 98 | MP0005499_abnormal_olfactory_system | 0.73345088 |
| 99 | MP0000026_abnormal_inner_ear | 0.73028501 |
| 100 | MP0002210_abnormal_sex_determination | 0.72415020 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.45238418 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.06876239 |
| 3 | Increased CSF lactate (HP:0002490) | 3.91148833 |
| 4 | Acute encephalopathy (HP:0006846) | 3.90473968 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.86223334 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.77411582 |
| 7 | Congenital stationary night blindness (HP:0007642) | 3.62755338 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.61116080 |
| 9 | Nephronophthisis (HP:0000090) | 3.59100954 |
| 10 | Abnormality of midbrain morphology (HP:0002418) | 3.58721035 |
| 11 | Molar tooth sign on MRI (HP:0002419) | 3.58721035 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 3.50101851 |
| 13 | Absent/shortened dynein arms (HP:0200106) | 3.33675306 |
| 14 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.33675306 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.27006005 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.13631633 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.13176843 |
| 18 | Methylmalonic acidemia (HP:0002912) | 3.08863100 |
| 19 | Optic disc pallor (HP:0000543) | 3.02951883 |
| 20 | Hepatic necrosis (HP:0002605) | 2.99816407 |
| 21 | Abnormality of the renal medulla (HP:0100957) | 2.97324893 |
| 22 | Hypoplasia of the fovea (HP:0007750) | 2.96566654 |
| 23 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.96566654 |
| 24 | Pancreatic cysts (HP:0001737) | 2.92137961 |
| 25 | Cerebral edema (HP:0002181) | 2.88223031 |
| 26 | Decreased central vision (HP:0007663) | 2.85628781 |
| 27 | Abnormal number of erythroid precursors (HP:0012131) | 2.82670509 |
| 28 | Type II lissencephaly (HP:0007260) | 2.66719319 |
| 29 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.63977720 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.60173449 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.58014454 |
| 32 | Abnormality of the renal cortex (HP:0011035) | 2.57751216 |
| 33 | 3-Methylglutaconic aciduria (HP:0003535) | 2.56089105 |
| 34 | Reticulocytopenia (HP:0001896) | 2.53898072 |
| 35 | Abnormality of the fovea (HP:0000493) | 2.49901185 |
| 36 | Methylmalonic aciduria (HP:0012120) | 2.48040879 |
| 37 | Congenital, generalized hypertrichosis (HP:0004540) | 2.45800875 |
| 38 | Renal cortical cysts (HP:0000803) | 2.41727469 |
| 39 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.38772286 |
| 40 | Abnormality of alanine metabolism (HP:0010916) | 2.38772286 |
| 41 | Hyperalaninemia (HP:0003348) | 2.38772286 |
| 42 | Macrocytic anemia (HP:0001972) | 2.38374445 |
| 43 | Increased serum lactate (HP:0002151) | 2.34508463 |
| 44 | Exertional dyspnea (HP:0002875) | 2.33384355 |
| 45 | Increased intramyocellular lipid droplets (HP:0012240) | 2.33031934 |
| 46 | Medial flaring of the eyebrow (HP:0010747) | 2.31942903 |
| 47 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.31404600 |
| 48 | Sclerocornea (HP:0000647) | 2.30851100 |
| 49 | Abnormality of renal resorption (HP:0011038) | 2.30679847 |
| 50 | True hermaphroditism (HP:0010459) | 2.29804384 |
| 51 | Abnormality of urine glucose concentration (HP:0011016) | 2.27199533 |
| 52 | Glycosuria (HP:0003076) | 2.27199533 |
| 53 | Leukodystrophy (HP:0002415) | 2.26584392 |
| 54 | Abolished electroretinogram (ERG) (HP:0000550) | 2.24918175 |
| 55 | Attenuation of retinal blood vessels (HP:0007843) | 2.22715278 |
| 56 | Lactic acidosis (HP:0003128) | 2.22266247 |
| 57 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.21280627 |
| 58 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.21280627 |
| 59 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.21020767 |
| 60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.19003563 |
| 61 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.15201719 |
| 62 | Increased muscle lipid content (HP:0009058) | 2.11119702 |
| 63 | Pendular nystagmus (HP:0012043) | 2.07281079 |
| 64 | Polydipsia (HP:0001959) | 2.06354844 |
| 65 | Abnormal drinking behavior (HP:0030082) | 2.06354844 |
| 66 | Abnormal ciliary motility (HP:0012262) | 2.05730240 |
| 67 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.03367843 |
| 68 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.02749273 |
| 69 | Optic nerve hypoplasia (HP:0000609) | 2.02414817 |
| 70 | Respiratory failure (HP:0002878) | 2.02285540 |
| 71 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.01176226 |
| 72 | Lethargy (HP:0001254) | 2.00262439 |
| 73 | Hypothermia (HP:0002045) | 1.99897254 |
| 74 | Agitation (HP:0000713) | 1.99467457 |
| 75 | IgG deficiency (HP:0004315) | 1.97849822 |
| 76 | Type 2 muscle fiber atrophy (HP:0003554) | 1.95865813 |
| 77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92792693 |
| 78 | Abnormality of vitamin B metabolism (HP:0004340) | 1.89754699 |
| 79 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.89337429 |
| 80 | Concave nail (HP:0001598) | 1.88965440 |
| 81 | Septo-optic dysplasia (HP:0100842) | 1.87496146 |
| 82 | Adrenal hypoplasia (HP:0000835) | 1.85969722 |
| 83 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.85309350 |
| 84 | Polyuria (HP:0000103) | 1.85170686 |
| 85 | Supernumerary spleens (HP:0009799) | 1.83187294 |
| 86 | Gait imbalance (HP:0002141) | 1.82951427 |
| 87 | Cerebellar dysplasia (HP:0007033) | 1.81965149 |
| 88 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.79527350 |
| 89 | Stomatitis (HP:0010280) | 1.74420618 |
| 90 | Exercise intolerance (HP:0003546) | 1.72773715 |
| 91 | Congenital sensorineural hearing impairment (HP:0008527) | 1.72555878 |
| 92 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.72523643 |
| 93 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.72523643 |
| 94 | Abnormal urine output (HP:0012590) | 1.71967651 |
| 95 | Postaxial foot polydactyly (HP:0001830) | 1.71803719 |
| 96 | Abnormal spermatogenesis (HP:0008669) | 1.70344240 |
| 97 | Respiratory difficulties (HP:0002880) | 1.69321592 |
| 98 | Retinal dysplasia (HP:0007973) | 1.68604579 |
| 99 | Congenital primary aphakia (HP:0007707) | 1.68207922 |
| 100 | Increased corneal curvature (HP:0100692) | 1.67090041 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K12 | 4.19037010 |
| 2 | TLK1 | 3.30606854 |
| 3 | BMPR1B | 3.09856001 |
| 4 | ZAK | 2.79680232 |
| 5 | WNK4 | 2.74313372 |
| 6 | BMPR2 | 2.32990189 |
| 7 | TXK | 2.30475819 |
| 8 | NUAK1 | 2.24232377 |
| 9 | FRK | 2.23007762 |
| 10 | SCYL2 | 2.14476305 |
| 11 | GRK1 | 2.12624813 |
| 12 | ADRBK2 | 1.96387122 |
| 13 | VRK2 | 1.92403372 |
| 14 | INSRR | 1.89478822 |
| 15 | DYRK2 | 1.77715486 |
| 16 | WNK3 | 1.76896109 |
| 17 | CDK19 | 1.72577097 |
| 18 | STK16 | 1.70716702 |
| 19 | ACVR1B | 1.65033313 |
| 20 | CASK | 1.64150007 |
| 21 | TRIM28 | 1.62691757 |
| 22 | BCKDK | 1.52941312 |
| 23 | MAP4K2 | 1.52268329 |
| 24 | MARK1 | 1.46533451 |
| 25 | STK39 | 1.46249254 |
| 26 | PLK4 | 1.42862899 |
| 27 | TIE1 | 1.41393918 |
| 28 | CSNK1G3 | 1.23563431 |
| 29 | CSNK1G2 | 1.19514633 |
| 30 | ERBB3 | 1.17523987 |
| 31 | OXSR1 | 1.09303001 |
| 32 | PDK2 | 1.07624597 |
| 33 | WEE1 | 1.05756775 |
| 34 | CSNK1A1L | 1.01487735 |
| 35 | MST4 | 1.00644949 |
| 36 | TGFBR1 | 0.97058755 |
| 37 | NEK2 | 0.94642865 |
| 38 | LIMK1 | 0.94168045 |
| 39 | VRK1 | 0.92595105 |
| 40 | MAP3K4 | 0.89540613 |
| 41 | CSNK1G1 | 0.88900625 |
| 42 | MAP2K7 | 0.88730215 |
| 43 | MAP2K4 | 0.83822591 |
| 44 | PHKG2 | 0.83706904 |
| 45 | PHKG1 | 0.83706904 |
| 46 | PLK3 | 0.81902641 |
| 47 | PAK3 | 0.79886451 |
| 48 | PINK1 | 0.78352684 |
| 49 | MARK3 | 0.75623735 |
| 50 | MAP3K11 | 0.75515326 |
| 51 | TEC | 0.75480469 |
| 52 | PLK2 | 0.74893607 |
| 53 | ADRBK1 | 0.73696462 |
| 54 | WNK1 | 0.72955685 |
| 55 | PRKCG | 0.68391868 |
| 56 | GRK6 | 0.68269950 |
| 57 | ILK | 0.67692113 |
| 58 | CDK3 | 0.64167693 |
| 59 | SRPK1 | 0.63729156 |
| 60 | MAPK13 | 0.61865542 |
| 61 | MKNK2 | 0.61548968 |
| 62 | MYLK | 0.60747242 |
| 63 | TAF1 | 0.59251850 |
| 64 | IKBKB | 0.58580563 |
| 65 | CAMK2A | 0.58051459 |
| 66 | EPHA4 | 0.56960810 |
| 67 | CSNK2A2 | 0.55491669 |
| 68 | BTK | 0.54939840 |
| 69 | PIK3CA | 0.54811818 |
| 70 | PLK1 | 0.53782307 |
| 71 | PRKACA | 0.53339828 |
| 72 | NME2 | 0.52155265 |
| 73 | MAP2K6 | 0.52081078 |
| 74 | NME1 | 0.52010032 |
| 75 | FES | 0.51415377 |
| 76 | NEK1 | 0.51239507 |
| 77 | CDK8 | 0.50719646 |
| 78 | AURKB | 0.50209381 |
| 79 | PRKCQ | 0.49912173 |
| 80 | SYK | 0.48174015 |
| 81 | LYN | 0.46833379 |
| 82 | ATR | 0.46025244 |
| 83 | MINK1 | 0.45969614 |
| 84 | CSNK2A1 | 0.44280193 |
| 85 | RPS6KA5 | 0.44143267 |
| 86 | DAPK2 | 0.44027419 |
| 87 | PIK3CG | 0.43337020 |
| 88 | MKNK1 | 0.43283113 |
| 89 | NTRK2 | 0.43229041 |
| 90 | OBSCN | 0.41293813 |
| 91 | PRKCA | 0.40693665 |
| 92 | CSNK1A1 | 0.40444293 |
| 93 | DAPK3 | 0.39620034 |
| 94 | PRKCE | 0.39096504 |
| 95 | EIF2AK2 | 0.38977259 |
| 96 | PKN1 | 0.37984158 |
| 97 | RPS6KA4 | 0.37499859 |
| 98 | KIT | 0.36370660 |
| 99 | TAOK3 | 0.36207564 |
| 100 | CAMK1 | 0.34974988 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.25008478 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.60286022 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.54790857 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.42996332 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.73031207 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.67035553 |
| 7 | Proteasome_Homo sapiens_hsa03050 | 2.65414519 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.43631506 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40338713 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.34971502 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.34170206 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.27545144 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25275230 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.11640193 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.11005855 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.07922648 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.99451419 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.98578297 |
| 19 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.94166808 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.85644485 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.61054563 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56506198 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.48893862 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.41041680 |
| 25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.36841046 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.32047819 |
| 27 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.19365687 |
| 28 | Nicotine addiction_Homo sapiens_hsa05033 | 1.15609065 |
| 29 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.14314567 |
| 30 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.13134708 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.11211865 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.08723214 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.08218873 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.05786236 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05641504 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.02245508 |
| 37 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.96881968 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.95875635 |
| 39 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.95164298 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 0.94794443 |
| 41 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.94388151 |
| 42 | Olfactory transduction_Homo sapiens_hsa04740 | 0.93783089 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.91047594 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89604885 |
| 45 | Mismatch repair_Homo sapiens_hsa03430 | 0.87636337 |
| 46 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.86473076 |
| 47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.84921823 |
| 48 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.83841706 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.83385036 |
| 50 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.82695698 |
| 51 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.82527479 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81347578 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.75198574 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75164764 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.74660225 |
| 56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.74643255 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.72321394 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71149162 |
| 59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.69216497 |
| 60 | DNA replication_Homo sapiens_hsa03030 | 0.68428021 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.65625521 |
| 62 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.65024455 |
| 63 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.64866175 |
| 64 | Morphine addiction_Homo sapiens_hsa05032 | 0.63899013 |
| 65 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61846400 |
| 66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.59628140 |
| 67 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58563338 |
| 68 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.56868637 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.56740086 |
| 70 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.56149637 |
| 71 | Viral myocarditis_Homo sapiens_hsa05416 | 0.55491348 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.53197271 |
| 73 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51357268 |
| 74 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51206761 |
| 75 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.49054950 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48228842 |
| 77 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.46962154 |
| 78 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46692173 |
| 79 | Taste transduction_Homo sapiens_hsa04742 | 0.45649773 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45559767 |
| 81 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43054541 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.41463788 |
| 83 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.40634442 |
| 84 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.40278380 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39878576 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37425164 |
| 87 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36335520 |
| 88 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.35526958 |
| 89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.35510841 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35079345 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.34900014 |
| 92 | GABAergic synapse_Homo sapiens_hsa04727 | 0.33989861 |
| 93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.31805793 |
| 94 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.31548455 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.31372119 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.29954376 |
| 97 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.27618971 |
| 98 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.26082197 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24693211 |
| 100 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.24425310 |

