

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 5.30247631 |
| 2 | translational termination (GO:0006415) | 5.18429319 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 5.06757379 |
| 4 | ribosomal large subunit biogenesis (GO:0042273) | 5.03342853 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.79680301 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 4.68737974 |
| 7 | protein targeting to ER (GO:0045047) | 4.64053831 |
| 8 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.62086301 |
| 9 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.62086301 |
| 10 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.58811097 |
| 11 | NADH dehydrogenase complex assembly (GO:0010257) | 4.58811097 |
| 12 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.58811097 |
| 13 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.52530170 |
| 14 | protein complex biogenesis (GO:0070271) | 4.52464680 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.49291964 |
| 16 | translational elongation (GO:0006414) | 4.47384212 |
| 17 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.43763448 |
| 18 | protein localization to endoplasmic reticulum (GO:0070972) | 4.40549352 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 4.40342666 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.40342666 |
| 21 | respiratory chain complex IV assembly (GO:0008535) | 4.38327290 |
| 22 | termination of RNA polymerase III transcription (GO:0006386) | 4.30485492 |
| 23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.30485492 |
| 24 | chaperone-mediated protein transport (GO:0072321) | 4.21203539 |
| 25 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.16828084 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.16039972 |
| 27 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.07863927 |
| 28 | ribosomal small subunit biogenesis (GO:0042274) | 3.98691135 |
| 29 | viral life cycle (GO:0019058) | 3.88791865 |
| 30 | DNA deamination (GO:0045006) | 3.80479814 |
| 31 | translational initiation (GO:0006413) | 3.79487644 |
| 32 | protein neddylation (GO:0045116) | 3.73092317 |
| 33 | cellular protein complex disassembly (GO:0043624) | 3.72842115 |
| 34 | maturation of SSU-rRNA (GO:0030490) | 3.72099502 |
| 35 | cytochrome complex assembly (GO:0017004) | 3.69793617 |
| 36 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.69671155 |
| 37 | translation (GO:0006412) | 3.68415317 |
| 38 | behavioral response to nicotine (GO:0035095) | 3.62882040 |
| 39 | cellular component biogenesis (GO:0044085) | 3.57922056 |
| 40 | aldehyde catabolic process (GO:0046185) | 3.54441744 |
| 41 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.50050324 |
| 42 | respiratory electron transport chain (GO:0022904) | 3.46315222 |
| 43 | electron transport chain (GO:0022900) | 3.45096448 |
| 44 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.42438058 |
| 45 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.38962686 |
| 46 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.18319363 |
| 47 | regulation of cellular respiration (GO:0043457) | 3.16750172 |
| 48 | platelet dense granule organization (GO:0060155) | 3.13863940 |
| 49 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.13717644 |
| 50 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.09005107 |
| 51 | GTP biosynthetic process (GO:0006183) | 3.08123584 |
| 52 | rRNA modification (GO:0000154) | 3.07663052 |
| 53 | ubiquinone biosynthetic process (GO:0006744) | 3.06519177 |
| 54 | protein targeting to membrane (GO:0006612) | 3.03412189 |
| 55 | protein complex disassembly (GO:0043241) | 3.02803631 |
| 56 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.93929657 |
| 57 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.89581914 |
| 58 | intracellular protein transmembrane import (GO:0044743) | 2.89518777 |
| 59 | piRNA metabolic process (GO:0034587) | 2.89393178 |
| 60 | protein localization to cilium (GO:0061512) | 2.89354182 |
| 61 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.88589134 |
| 62 | macromolecular complex disassembly (GO:0032984) | 2.87745723 |
| 63 | protein-cofactor linkage (GO:0018065) | 2.87467194 |
| 64 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.86544943 |
| 65 | tRNA processing (GO:0008033) | 2.86041741 |
| 66 | positive regulation of interleukin-17 production (GO:0032740) | 2.83021988 |
| 67 | iron-sulfur cluster assembly (GO:0016226) | 2.81336204 |
| 68 | metallo-sulfur cluster assembly (GO:0031163) | 2.81336204 |
| 69 | ATP biosynthetic process (GO:0006754) | 2.79730636 |
| 70 | rRNA processing (GO:0006364) | 2.79090567 |
| 71 | protein prenylation (GO:0018342) | 2.77125542 |
| 72 | prenylation (GO:0097354) | 2.77125542 |
| 73 | mRNA catabolic process (GO:0006402) | 2.75543998 |
| 74 | response to pheromone (GO:0019236) | 2.73937860 |
| 75 | rRNA metabolic process (GO:0016072) | 2.72536171 |
| 76 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.69628644 |
| 77 | ubiquinone metabolic process (GO:0006743) | 2.69020741 |
| 78 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.67898593 |
| 79 | regulation of cilium movement (GO:0003352) | 2.66212719 |
| 80 | peptidyl-histidine modification (GO:0018202) | 2.65276623 |
| 81 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.64893901 |
| 82 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.63388231 |
| 83 | pseudouridine synthesis (GO:0001522) | 2.63222502 |
| 84 | protein targeting to mitochondrion (GO:0006626) | 2.61789191 |
| 85 | base-excision repair, AP site formation (GO:0006285) | 2.61582408 |
| 86 | regulation of chronic inflammatory response (GO:0002676) | 2.60030197 |
| 87 | ribosome biogenesis (GO:0042254) | 2.59674784 |
| 88 | proteasome assembly (GO:0043248) | 2.58949546 |
| 89 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.58433874 |
| 90 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.56453517 |
| 91 | establishment of protein localization to mitochondrion (GO:0072655) | 2.56015988 |
| 92 | RNA catabolic process (GO:0006401) | 2.55679722 |
| 93 | L-fucose catabolic process (GO:0042355) | 2.54196053 |
| 94 | fucose catabolic process (GO:0019317) | 2.54196053 |
| 95 | L-fucose metabolic process (GO:0042354) | 2.54196053 |
| 96 | UTP biosynthetic process (GO:0006228) | 2.53477146 |
| 97 | regulation of immunoglobulin secretion (GO:0051023) | 2.52390198 |
| 98 | hydrogen ion transmembrane transport (GO:1902600) | 2.49433240 |
| 99 | tRNA metabolic process (GO:0006399) | 2.47506522 |
| 100 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.45762619 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.14835496 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.05619458 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.40183459 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.13479266 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.11822822 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.01302534 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.89135324 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.84256455 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.74658502 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.53876625 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.47938464 |
| 12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.44178480 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.36655382 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.30985767 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.22770036 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.09585535 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.02097853 |
| 18 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.98325415 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.97693207 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.90794223 |
| 21 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.84420322 |
| 22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.83721651 |
| 23 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.81866355 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.81366965 |
| 25 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.80830216 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77495755 |
| 27 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.73387667 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.68620340 |
| 29 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.60824014 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.59692532 |
| 31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59234556 |
| 32 | P300_19829295_ChIP-Seq_ESCs_Human | 1.55227167 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.50257168 |
| 34 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.48175053 |
| 35 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47045985 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.44295209 |
| 37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.43238699 |
| 38 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.42253983 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.41080291 |
| 40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40835520 |
| 41 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.36529698 |
| 42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.33946900 |
| 43 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.33946900 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.33665175 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.32553858 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.32553858 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.28908759 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28476315 |
| 49 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.24224675 |
| 50 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.24224675 |
| 51 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.21603557 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.19637050 |
| 53 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.19398804 |
| 54 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.18967981 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.18516858 |
| 56 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.18131909 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17955341 |
| 58 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14514553 |
| 59 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14267119 |
| 60 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.13179445 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.12605861 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.11680379 |
| 63 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.11670789 |
| 64 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.10624468 |
| 65 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.10036923 |
| 66 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.09668165 |
| 67 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.09553529 |
| 68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09361411 |
| 69 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.09253518 |
| 70 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.07230790 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07000556 |
| 72 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.06047913 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.04780988 |
| 74 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.03726377 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03232392 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01239988 |
| 77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.01214388 |
| 78 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.00895214 |
| 79 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.00662782 |
| 80 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99856806 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.99078859 |
| 82 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.98785889 |
| 83 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98338885 |
| 84 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98176996 |
| 85 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97251227 |
| 86 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.96780851 |
| 87 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95992536 |
| 88 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.95811573 |
| 89 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.95739452 |
| 90 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.95507712 |
| 91 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94313097 |
| 92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.94056957 |
| 93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93158526 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.92384628 |
| 95 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.92138653 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.91965702 |
| 97 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.91892543 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.91338516 |
| 99 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89561687 |
| 100 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88677676 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.00734062 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.45300386 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 3.22845432 |
| 4 | MP0002102_abnormal_ear_morphology | 2.83861713 |
| 5 | MP0003787_abnormal_imprinting | 2.81170316 |
| 6 | MP0002163_abnormal_gland_morphology | 2.61503722 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.41414806 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.31548596 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.30328183 |
| 10 | MP0004147_increased_porphyrin_level | 2.29746110 |
| 11 | MP0005379_endocrine/exocrine_gland_phen | 2.27182948 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.25123528 |
| 13 | MP0002876_abnormal_thyroid_physiology | 2.15840000 |
| 14 | MP0008872_abnormal_physiological_respon | 2.09838147 |
| 15 | MP0003878_abnormal_ear_physiology | 2.08465293 |
| 16 | MP0005377_hearing/vestibular/ear_phenot | 2.08465293 |
| 17 | MP0005671_abnormal_response_to | 2.01492410 |
| 18 | MP0004142_abnormal_muscle_tone | 1.97654075 |
| 19 | MP0000372_irregular_coat_pigmentation | 1.96561950 |
| 20 | MP0005646_abnormal_pituitary_gland | 1.93387583 |
| 21 | MP0003186_abnormal_redox_activity | 1.92584424 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 1.89636325 |
| 23 | MP0004084_abnormal_cardiac_muscle | 1.82558178 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.80426308 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.77236617 |
| 26 | MP0002138_abnormal_hepatobiliary_system | 1.70235278 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.59768114 |
| 28 | MP0002160_abnormal_reproductive_system | 1.58887759 |
| 29 | MP0001348_abnormal_lacrimal_gland | 1.56274139 |
| 30 | MP0008875_abnormal_xenobiotic_pharmacok | 1.54296090 |
| 31 | MP0005389_reproductive_system_phenotype | 1.42929691 |
| 32 | MP0001529_abnormal_vocalization | 1.40728589 |
| 33 | MP0006036_abnormal_mitochondrial_physio | 1.36228246 |
| 34 | MP0003011_delayed_dark_adaptation | 1.35682140 |
| 35 | MP0001968_abnormal_touch/_nociception | 1.34551151 |
| 36 | MP0009785_altered_susceptibility_to | 1.34517606 |
| 37 | MP0003567_abnormal_fetal_cardiomyocyte | 1.34007472 |
| 38 | MP0006072_abnormal_retinal_apoptosis | 1.32620870 |
| 39 | MP0001764_abnormal_homeostasis | 1.27143284 |
| 40 | MP0005394_taste/olfaction_phenotype | 1.15753036 |
| 41 | MP0005499_abnormal_olfactory_system | 1.15753036 |
| 42 | MP0002148_abnormal_hypersensitivity_rea | 1.15123499 |
| 43 | MP0001800_abnormal_humoral_immune | 1.14301166 |
| 44 | MP0009333_abnormal_splenocyte_physiolog | 1.14210429 |
| 45 | MP0005410_abnormal_fertilization | 1.14065752 |
| 46 | MP0006276_abnormal_autonomic_nervous | 1.13132535 |
| 47 | MP0001905_abnormal_dopamine_level | 1.09872396 |
| 48 | MP0000685_abnormal_immune_system | 1.09471443 |
| 49 | MP0001984_abnormal_olfaction | 1.06625340 |
| 50 | MP0001293_anophthalmia | 1.06296178 |
| 51 | MP0003718_maternal_effect | 1.05959187 |
| 52 | MP0003646_muscle_fatigue | 1.05478978 |
| 53 | MP0003195_calcinosis | 1.02773286 |
| 54 | MP0004885_abnormal_endolymph | 1.02366346 |
| 55 | MP0001919_abnormal_reproductive_system | 0.99310682 |
| 56 | MP0001502_abnormal_circadian_rhythm | 0.99264311 |
| 57 | MP0002736_abnormal_nociception_after | 0.99172239 |
| 58 | MP0001986_abnormal_taste_sensitivity | 0.99005693 |
| 59 | MP0006054_spinal_hemorrhage | 0.98476288 |
| 60 | MP0002095_abnormal_skin_pigmentation | 0.97157319 |
| 61 | MP0005253_abnormal_eye_physiology | 0.97033471 |
| 62 | MP0006035_abnormal_mitochondrial_morpho | 0.96924680 |
| 63 | MP0003880_abnormal_central_pattern | 0.96740616 |
| 64 | MP0003252_abnormal_bile_duct | 0.95700480 |
| 65 | MP0002132_abnormal_respiratory_system | 0.94103494 |
| 66 | MP0005332_abnormal_amino_acid | 0.93579919 |
| 67 | MP0008775_abnormal_heart_ventricle | 0.93561840 |
| 68 | MP0009764_decreased_sensitivity_to | 0.92117279 |
| 69 | MP0002277_abnormal_respiratory_mucosa | 0.91322521 |
| 70 | MP0009745_abnormal_behavioral_response | 0.91233279 |
| 71 | MP0002733_abnormal_thermal_nociception | 0.90814862 |
| 72 | MP0002272_abnormal_nervous_system | 0.90599293 |
| 73 | MP0003121_genomic_imprinting | 0.89467419 |
| 74 | MP0001970_abnormal_pain_threshold | 0.88459313 |
| 75 | MP0002693_abnormal_pancreas_physiology | 0.87319846 |
| 76 | MP0005075_abnormal_melanosome_morpholog | 0.85310461 |
| 77 | MP0003806_abnormal_nucleotide_metabolis | 0.83088532 |
| 78 | MP0000631_abnormal_neuroendocrine_gland | 0.82906463 |
| 79 | MP0005636_abnormal_mineral_homeostasis | 0.81693813 |
| 80 | MP0002822_catalepsy | 0.79682171 |
| 81 | MP0002210_abnormal_sex_determination | 0.78042675 |
| 82 | MP0000230_abnormal_systemic_arterial | 0.77059413 |
| 83 | MP0002735_abnormal_chemical_nociception | 0.76641650 |
| 84 | MP0008058_abnormal_DNA_repair | 0.76627184 |
| 85 | MP0004036_abnormal_muscle_relaxation | 0.76407672 |
| 86 | MP0000049_abnormal_middle_ear | 0.75373547 |
| 87 | MP0004215_abnormal_myocardial_fiber | 0.74123904 |
| 88 | MP0001485_abnormal_pinna_reflex | 0.72991689 |
| 89 | MP0002006_tumorigenesis | 0.72627971 |
| 90 | MP0003786_premature_aging | 0.70854331 |
| 91 | MP0010155_abnormal_intestine_physiology | 0.69478524 |
| 92 | MP0001486_abnormal_startle_reflex | 0.67062663 |
| 93 | MP0001929_abnormal_gametogenesis | 0.66279946 |
| 94 | MP0009046_muscle_twitch | 0.64744611 |
| 95 | MP0002723_abnormal_immune_serum | 0.64619649 |
| 96 | MP0001145_abnormal_male_reproductive | 0.64113173 |
| 97 | MP0002751_abnormal_autonomic_nervous | 0.62670153 |
| 98 | MP0005195_abnormal_posterior_eye | 0.62602155 |
| 99 | MP0001963_abnormal_hearing_physiology | 0.62244891 |
| 100 | MP0001119_abnormal_female_reproductive | 0.62168546 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.83232394 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.51229811 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.32580687 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.10760602 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.04195028 |
| 6 | Increased CSF lactate (HP:0002490) | 4.02706254 |
| 7 | Acute encephalopathy (HP:0006846) | 3.98281231 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.84349423 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.84349423 |
| 10 | Hypoproteinemia (HP:0003075) | 3.81356320 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.53710405 |
| 12 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.53273835 |
| 13 | B lymphocytopenia (HP:0010976) | 3.51202585 |
| 14 | Hepatic necrosis (HP:0002605) | 3.48999977 |
| 15 | Pancreatic cysts (HP:0001737) | 3.36440896 |
| 16 | Abnormality of B cell number (HP:0010975) | 3.28441486 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 3.24367493 |
| 18 | Pancreatic fibrosis (HP:0100732) | 3.22289371 |
| 19 | Nephronophthisis (HP:0000090) | 3.21368323 |
| 20 | Lipid accumulation in hepatocytes (HP:0006561) | 3.19969630 |
| 21 | True hermaphroditism (HP:0010459) | 3.16482845 |
| 22 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.11080400 |
| 23 | Cerebral edema (HP:0002181) | 3.10287490 |
| 24 | Optic disc pallor (HP:0000543) | 3.02089932 |
| 25 | Chronic hepatic failure (HP:0100626) | 2.91292623 |
| 26 | Absent/shortened dynein arms (HP:0200106) | 2.90968307 |
| 27 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.90968307 |
| 28 | Increased serum lactate (HP:0002151) | 2.88064456 |
| 29 | IgG deficiency (HP:0004315) | 2.73331477 |
| 30 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.69602725 |
| 31 | Renal Fanconi syndrome (HP:0001994) | 2.67472535 |
| 32 | Severe combined immunodeficiency (HP:0004430) | 2.57104860 |
| 33 | Abnormal number of erythroid precursors (HP:0012131) | 2.53694831 |
| 34 | Abnormality of the renal medulla (HP:0100957) | 2.51991825 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.51749471 |
| 36 | Methylmalonic acidemia (HP:0002912) | 2.51343780 |
| 37 | Panhypogammaglobulinemia (HP:0003139) | 2.45384610 |
| 38 | Macrocytic anemia (HP:0001972) | 2.44988799 |
| 39 | Thyroiditis (HP:0100646) | 2.44585336 |
| 40 | Attenuation of retinal blood vessels (HP:0007843) | 2.42430205 |
| 41 | Lactic acidosis (HP:0003128) | 2.35962908 |
| 42 | Leukodystrophy (HP:0002415) | 2.35462633 |
| 43 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.35261834 |
| 44 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.35261834 |
| 45 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.32126203 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.30408722 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.30408722 |
| 48 | Type 2 muscle fiber atrophy (HP:0003554) | 2.27592200 |
| 49 | Abnormal ciliary motility (HP:0012262) | 2.27341477 |
| 50 | Type II lissencephaly (HP:0007260) | 2.27309116 |
| 51 | Respiratory failure (HP:0002878) | 2.27163634 |
| 52 | Decreased central vision (HP:0007663) | 2.25601781 |
| 53 | Reticulocytopenia (HP:0001896) | 2.24018118 |
| 54 | Abolished electroretinogram (ERG) (HP:0000550) | 2.23942781 |
| 55 | Cystic liver disease (HP:0006706) | 2.23897644 |
| 56 | Abnormality of the pons (HP:0007361) | 2.19001342 |
| 57 | Increased muscle lipid content (HP:0009058) | 2.18076761 |
| 58 | Stenosis of the external auditory canal (HP:0000402) | 2.16260670 |
| 59 | Stomatitis (HP:0010280) | 2.14442472 |
| 60 | Constricted visual fields (HP:0001133) | 2.13931504 |
| 61 | Pendular nystagmus (HP:0012043) | 2.12011639 |
| 62 | Postaxial foot polydactyly (HP:0001830) | 2.10108950 |
| 63 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.07626539 |
| 64 | Exercise intolerance (HP:0003546) | 2.07609561 |
| 65 | Erythroderma (HP:0001019) | 2.07434651 |
| 66 | Hypoplasia of the pons (HP:0012110) | 2.07377572 |
| 67 | Sclerocornea (HP:0000647) | 2.07248818 |
| 68 | Congenital stationary night blindness (HP:0007642) | 2.07150394 |
| 69 | Lethargy (HP:0001254) | 2.04194693 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.02521589 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 2.01502570 |
| 72 | Glycosuria (HP:0003076) | 2.01502570 |
| 73 | Exertional dyspnea (HP:0002875) | 2.00457402 |
| 74 | Medial flaring of the eyebrow (HP:0010747) | 1.96667195 |
| 75 | Methylmalonic aciduria (HP:0012120) | 1.95231449 |
| 76 | CNS demyelination (HP:0007305) | 1.92732516 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.92701840 |
| 78 | Male pseudohermaphroditism (HP:0000037) | 1.92166591 |
| 79 | Abnormality of renal resorption (HP:0011038) | 1.91392458 |
| 80 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.90533877 |
| 81 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.88549782 |
| 82 | Abnormality of alanine metabolism (HP:0010916) | 1.88549782 |
| 83 | Hyperalaninemia (HP:0003348) | 1.88549782 |
| 84 | Muscle fiber atrophy (HP:0100295) | 1.86841736 |
| 85 | Chronic sinusitis (HP:0011109) | 1.85732883 |
| 86 | Cerebellar dysplasia (HP:0007033) | 1.85341437 |
| 87 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.84514472 |
| 88 | Hypoplasia of the thymus (HP:0000778) | 1.80923783 |
| 89 | Combined immunodeficiency (HP:0005387) | 1.76843805 |
| 90 | Eosinophilia (HP:0001880) | 1.76424830 |
| 91 | Cleft eyelid (HP:0000625) | 1.76171616 |
| 92 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.75909497 |
| 93 | Pallor (HP:0000980) | 1.75722189 |
| 94 | Polydipsia (HP:0001959) | 1.72210648 |
| 95 | Abnormal drinking behavior (HP:0030082) | 1.72210648 |
| 96 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.72192675 |
| 97 | Testicular atrophy (HP:0000029) | 1.70097971 |
| 98 | Microvesicular hepatic steatosis (HP:0001414) | 1.67658892 |
| 99 | X-linked dominant inheritance (HP:0001423) | 1.64536379 |
| 100 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.63897826 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PASK | 4.15390049 |
| 2 | TXK | 3.92784505 |
| 3 | ZAK | 3.07049091 |
| 4 | ADRBK2 | 2.82736548 |
| 5 | MAP3K12 | 2.49628397 |
| 6 | CDK19 | 2.48342482 |
| 7 | WNK4 | 2.30436856 |
| 8 | GRK1 | 2.28164594 |
| 9 | BCKDK | 2.19231740 |
| 10 | STK16 | 2.09637659 |
| 11 | TLK1 | 1.94274639 |
| 12 | INSRR | 1.84165491 |
| 13 | PBK | 1.84012168 |
| 14 | NEK1 | 1.80606707 |
| 15 | MAP4K1 | 1.75571581 |
| 16 | FRK | 1.73474872 |
| 17 | NUAK1 | 1.68845330 |
| 18 | BUB1 | 1.67679280 |
| 19 | DYRK2 | 1.67273560 |
| 20 | PIK3CG | 1.51851068 |
| 21 | SCYL2 | 1.50054603 |
| 22 | PINK1 | 1.46600317 |
| 23 | CAMKK1 | 1.45900443 |
| 24 | BMPR1B | 1.42069579 |
| 25 | WNK3 | 1.40993295 |
| 26 | TAOK3 | 1.40240822 |
| 27 | TIE1 | 1.37180585 |
| 28 | MST4 | 1.33915833 |
| 29 | MAP3K13 | 1.32155410 |
| 30 | STK39 | 1.23694796 |
| 31 | EIF2AK3 | 1.19446089 |
| 32 | CAMKK2 | 1.16726357 |
| 33 | MUSK | 1.10562279 |
| 34 | MAP4K2 | 1.09054078 |
| 35 | TRIM28 | 1.08628701 |
| 36 | NME2 | 1.08509533 |
| 37 | TEC | 1.06631356 |
| 38 | MAP2K6 | 0.97353035 |
| 39 | OXSR1 | 0.97270460 |
| 40 | ITK | 0.96726975 |
| 41 | VRK1 | 0.94853060 |
| 42 | IKBKB | 0.90879139 |
| 43 | PRKCQ | 0.90668852 |
| 44 | STK38L | 0.88035077 |
| 45 | TGFBR1 | 0.87796059 |
| 46 | NME1 | 0.86006146 |
| 47 | BMPR2 | 0.85973400 |
| 48 | TSSK6 | 0.84814562 |
| 49 | PLK4 | 0.82442273 |
| 50 | BRSK2 | 0.76215601 |
| 51 | BTK | 0.73256716 |
| 52 | MAP3K4 | 0.72818173 |
| 53 | ADRBK1 | 0.72622236 |
| 54 | EIF2AK1 | 0.71705736 |
| 55 | SYK | 0.70315475 |
| 56 | VRK2 | 0.69666769 |
| 57 | PLK3 | 0.69527618 |
| 58 | MAP3K14 | 0.68705079 |
| 59 | FES | 0.68411080 |
| 60 | CASK | 0.67112736 |
| 61 | DAPK2 | 0.67043904 |
| 62 | KIT | 0.65657894 |
| 63 | RPS6KA5 | 0.64005911 |
| 64 | LYN | 0.60845893 |
| 65 | NEK2 | 0.59969268 |
| 66 | PRKCE | 0.59549890 |
| 67 | CSNK1G3 | 0.58885991 |
| 68 | PRKCG | 0.58528072 |
| 69 | MATK | 0.57755092 |
| 70 | CSNK1G2 | 0.54744012 |
| 71 | CSNK1G1 | 0.51574514 |
| 72 | LCK | 0.50454983 |
| 73 | MYLK | 0.48836739 |
| 74 | MKNK1 | 0.48191363 |
| 75 | ATR | 0.48150108 |
| 76 | MAPK13 | 0.47850790 |
| 77 | TAF1 | 0.47782473 |
| 78 | CSNK2A2 | 0.47692904 |
| 79 | PLK1 | 0.46458956 |
| 80 | TNK2 | 0.45238039 |
| 81 | OBSCN | 0.43851507 |
| 82 | LRRK2 | 0.43818370 |
| 83 | CSNK2A1 | 0.43630731 |
| 84 | SIK2 | 0.42686061 |
| 85 | PIM2 | 0.40426571 |
| 86 | PRKD3 | 0.40108390 |
| 87 | MKNK2 | 0.39852987 |
| 88 | CSNK1E | 0.38400003 |
| 89 | DAPK1 | 0.38338616 |
| 90 | PRKACA | 0.38282277 |
| 91 | PRKCA | 0.36548842 |
| 92 | PRKG1 | 0.36501932 |
| 93 | JAK3 | 0.32608196 |
| 94 | PRKCD | 0.31406726 |
| 95 | PRKCH | 0.30725567 |
| 96 | CSNK1A1L | 0.30439075 |
| 97 | ABL2 | 0.30184104 |
| 98 | PHKG1 | 0.29562794 |
| 99 | PHKG2 | 0.29562794 |
| 100 | CSF1R | 0.29124982 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.69207452 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.52801516 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.17678230 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.02113122 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.01841910 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.97905235 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.95135633 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.56042294 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.40546611 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.13373068 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.06482976 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96674183 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.96032181 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.93189254 |
| 15 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.87872206 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.86513386 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.84630026 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.77098716 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.76563730 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.65214325 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.54281081 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52867062 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.50454367 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.46438133 |
| 25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.45426621 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.39001208 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.38313467 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.38184166 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.36725822 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34684169 |
| 31 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.33142823 |
| 32 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.26279736 |
| 33 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.19679200 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19021446 |
| 35 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.12289052 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.11946852 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.10323948 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.08109215 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.04583691 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.02456101 |
| 41 | Mismatch repair_Homo sapiens_hsa03430 | 1.00036157 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.99089187 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97519126 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 0.95473411 |
| 45 | Base excision repair_Homo sapiens_hsa03410 | 0.94092549 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.93909533 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.92747858 |
| 48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.91897667 |
| 49 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.91571981 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.90275824 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85326631 |
| 52 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83513491 |
| 53 | DNA replication_Homo sapiens_hsa03030 | 0.83063310 |
| 54 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.79761007 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.76945787 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69418130 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.67195857 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64942579 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.64356800 |
| 60 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.64221978 |
| 61 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.60427047 |
| 62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59034622 |
| 63 | Spliceosome_Homo sapiens_hsa03040 | 0.58794946 |
| 64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.57765147 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.55399342 |
| 66 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.54519346 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.54395457 |
| 68 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.54375807 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54138784 |
| 70 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.54112383 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51637395 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51522251 |
| 73 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.49748744 |
| 74 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48532462 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47812993 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.47327457 |
| 77 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.47115171 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46737407 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46508660 |
| 80 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45895356 |
| 81 | Sulfur relay system_Homo sapiens_hsa04122 | 0.43520394 |
| 82 | Nicotine addiction_Homo sapiens_hsa05033 | 0.43111445 |
| 83 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.42553726 |
| 84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.41930169 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.41004988 |
| 86 | Viral myocarditis_Homo sapiens_hsa05416 | 0.40763319 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39517686 |
| 88 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37648036 |
| 89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36664471 |
| 90 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.33335761 |
| 91 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33037249 |
| 92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32460167 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.32310576 |
| 94 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.30716398 |
| 95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.28546554 |
| 96 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28333061 |
| 97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27715933 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.26521893 |
| 99 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23310325 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.20973147 |

