

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ATP synthesis coupled proton transport (GO:0015986) | 5.89246672 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.89246672 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 5.76975628 |
| 4 | DNA deamination (GO:0045006) | 5.43807863 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.29669175 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 5.03752211 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 4.91396035 |
| 8 | ribosomal large subunit biogenesis (GO:0042273) | 4.77113791 |
| 9 | viral transcription (GO:0019083) | 4.64323558 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.59022463 |
| 11 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.57973391 |
| 12 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.57178524 |
| 13 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.57178524 |
| 14 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.54513056 |
| 15 | translational termination (GO:0006415) | 4.53258336 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.37187354 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.32771160 |
| 18 | protein complex biogenesis (GO:0070271) | 4.31495945 |
| 19 | cotranslational protein targeting to membrane (GO:0006613) | 4.29624787 |
| 20 | protein neddylation (GO:0045116) | 4.29401813 |
| 21 | ribosomal small subunit biogenesis (GO:0042274) | 4.28888048 |
| 22 | protein targeting to ER (GO:0045047) | 4.26738533 |
| 23 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.24063731 |
| 24 | respiratory electron transport chain (GO:0022904) | 4.11648584 |
| 25 | translational elongation (GO:0006414) | 4.08267233 |
| 26 | electron transport chain (GO:0022900) | 4.08266268 |
| 27 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.07162145 |
| 28 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.05107580 |
| 29 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.05107580 |
| 30 | NADH dehydrogenase complex assembly (GO:0010257) | 4.05107580 |
| 31 | protein localization to endoplasmic reticulum (GO:0070972) | 4.03085517 |
| 32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.02073612 |
| 33 | GTP biosynthetic process (GO:0006183) | 3.82494723 |
| 34 | termination of RNA polymerase III transcription (GO:0006386) | 3.71763324 |
| 35 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.71763324 |
| 36 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.67659829 |
| 37 | translation (GO:0006412) | 3.65994701 |
| 38 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.45506908 |
| 39 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.45177355 |
| 40 | proteasome assembly (GO:0043248) | 3.40665000 |
| 41 | translational initiation (GO:0006413) | 3.40517662 |
| 42 | respiratory chain complex IV assembly (GO:0008535) | 3.39953574 |
| 43 | viral life cycle (GO:0019058) | 3.38609790 |
| 44 | ATP biosynthetic process (GO:0006754) | 3.33826545 |
| 45 | cellular component biogenesis (GO:0044085) | 3.32878773 |
| 46 | rRNA modification (GO:0000154) | 3.32838818 |
| 47 | cellular protein complex disassembly (GO:0043624) | 3.30824568 |
| 48 | aldehyde catabolic process (GO:0046185) | 3.29132094 |
| 49 | cytochrome complex assembly (GO:0017004) | 3.26376622 |
| 50 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.25633663 |
| 51 | base-excision repair, AP site formation (GO:0006285) | 3.20037799 |
| 52 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.19986334 |
| 53 | UTP biosynthetic process (GO:0006228) | 3.18518406 |
| 54 | behavioral response to nicotine (GO:0035095) | 3.15961459 |
| 55 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.08158813 |
| 56 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.06585454 |
| 57 | signal peptide processing (GO:0006465) | 3.05673862 |
| 58 | hydrogen ion transmembrane transport (GO:1902600) | 3.04436752 |
| 59 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.04016319 |
| 60 | protein polyglutamylation (GO:0018095) | 3.03941949 |
| 61 | rRNA processing (GO:0006364) | 3.02377831 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.00324414 |
| 63 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.99278412 |
| 64 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.98472828 |
| 65 | rRNA metabolic process (GO:0016072) | 2.97587587 |
| 66 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.97528428 |
| 67 | maturation of 5.8S rRNA (GO:0000460) | 2.97142149 |
| 68 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.96312839 |
| 69 | UTP metabolic process (GO:0046051) | 2.95741595 |
| 70 | tRNA processing (GO:0008033) | 2.95721642 |
| 71 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.95029057 |
| 72 | protein deneddylation (GO:0000338) | 2.91909456 |
| 73 | GPI anchor metabolic process (GO:0006505) | 2.91762453 |
| 74 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.90514119 |
| 75 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.90514119 |
| 76 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.90514119 |
| 77 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.89533985 |
| 78 | proton transport (GO:0015992) | 2.87197614 |
| 79 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.85716946 |
| 80 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.85716946 |
| 81 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.84355042 |
| 82 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.84352692 |
| 83 | protein targeting to mitochondrion (GO:0006626) | 2.83443280 |
| 84 | hydrogen transport (GO:0006818) | 2.82837780 |
| 85 | GPI anchor biosynthetic process (GO:0006506) | 2.82415415 |
| 86 | pseudouridine synthesis (GO:0001522) | 2.80418484 |
| 87 | protein targeting to membrane (GO:0006612) | 2.77908608 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.74265310 |
| 89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.74265310 |
| 90 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.70872522 |
| 91 | cytidine metabolic process (GO:0046087) | 2.70372566 |
| 92 | cytidine catabolic process (GO:0006216) | 2.70372566 |
| 93 | cytidine deamination (GO:0009972) | 2.70372566 |
| 94 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.70120921 |
| 95 | negative regulation of ligase activity (GO:0051352) | 2.70120921 |
| 96 | intracellular protein transmembrane import (GO:0044743) | 2.69597528 |
| 97 | establishment of protein localization to mitochondrion (GO:0072655) | 2.68795734 |
| 98 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.67476835 |
| 99 | protein complex disassembly (GO:0043241) | 2.66537981 |
| 100 | mRNA catabolic process (GO:0006402) | 2.66177981 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.51564736 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.47534791 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.86675911 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.53560027 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.16652731 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.14801884 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.09056125 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91986858 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.81694439 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.66275700 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.59210994 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.58858164 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.55867351 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.39495664 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.35783853 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.25581126 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.16463585 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.11823421 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10096778 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.01264133 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.00456009 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.98273177 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.85707949 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.77469593 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.75208107 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.74624349 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71315221 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.55446606 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54569494 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.53584127 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.53508860 |
| 32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47087279 |
| 33 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43192408 |
| 34 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.43049240 |
| 35 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.42691054 |
| 36 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.41806868 |
| 37 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.41033818 |
| 38 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39748577 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.36358980 |
| 40 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.36341821 |
| 41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.35929193 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35642409 |
| 43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33221338 |
| 44 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32775271 |
| 45 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.32572917 |
| 46 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.30889884 |
| 47 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.30889884 |
| 48 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28241525 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.27968746 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.26999967 |
| 51 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.26128955 |
| 52 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.24490989 |
| 53 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.24382229 |
| 54 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.22918774 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.21756137 |
| 56 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.21406548 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.19109600 |
| 58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.18349615 |
| 59 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.18124640 |
| 60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.17528743 |
| 61 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.15963098 |
| 62 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.15063520 |
| 63 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14642330 |
| 64 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.14450571 |
| 65 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12848734 |
| 66 | P300_19829295_ChIP-Seq_ESCs_Human | 1.12557663 |
| 67 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.12194164 |
| 68 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.12113030 |
| 69 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.10926491 |
| 70 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.10795952 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09664819 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09664819 |
| 73 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.09554676 |
| 74 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09049794 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08947265 |
| 76 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.06287738 |
| 77 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.05574211 |
| 78 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.05561012 |
| 79 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04894655 |
| 80 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.04512094 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.03908421 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 1.02804589 |
| 83 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01131398 |
| 84 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.99824164 |
| 85 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99471862 |
| 86 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96899769 |
| 87 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96899769 |
| 88 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.95265214 |
| 89 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.93271383 |
| 90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.92729338 |
| 91 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92570073 |
| 92 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.92251144 |
| 93 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.90675954 |
| 94 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.90518566 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89863950 |
| 96 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.89370201 |
| 97 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.88157738 |
| 98 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87606653 |
| 99 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.87177698 |
| 100 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.86599366 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.85667700 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.30951938 |
| 3 | MP0005671_abnormal_response_to | 3.08330850 |
| 4 | MP0001835_abnormal_antigen_presentation | 2.93317769 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.75027761 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.33636436 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.32287737 |
| 8 | MP0004147_increased_porphyrin_level | 2.20451447 |
| 9 | MP0003195_calcinosis | 2.15635659 |
| 10 | MP0003646_muscle_fatigue | 2.12231843 |
| 11 | MP0002163_abnormal_gland_morphology | 2.05507276 |
| 12 | MP0002102_abnormal_ear_morphology | 1.99939379 |
| 13 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91026200 |
| 14 | MP0008872_abnormal_physiological_respon | 1.90439624 |
| 15 | MP0002736_abnormal_nociception_after | 1.90369883 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 1.90103722 |
| 17 | MP0003011_delayed_dark_adaptation | 1.89815314 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.87248790 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.84237085 |
| 20 | MP0008058_abnormal_DNA_repair | 1.75916756 |
| 21 | MP0003787_abnormal_imprinting | 1.73889979 |
| 22 | MP0001968_abnormal_touch/_nociception | 1.73456261 |
| 23 | MP0003786_premature_aging | 1.72076832 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.69806548 |
| 25 | MP0001529_abnormal_vocalization | 1.67498458 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.66530064 |
| 27 | MP0006036_abnormal_mitochondrial_physio | 1.64916704 |
| 28 | MP0003806_abnormal_nucleotide_metabolis | 1.63037709 |
| 29 | MP0004142_abnormal_muscle_tone | 1.61903263 |
| 30 | MP0002138_abnormal_hepatobiliary_system | 1.60832822 |
| 31 | MP0002638_abnormal_pupillary_reflex | 1.60729586 |
| 32 | MP0005379_endocrine/exocrine_gland_phen | 1.52143590 |
| 33 | MP0002876_abnormal_thyroid_physiology | 1.51856435 |
| 34 | MP0005084_abnormal_gallbladder_morpholo | 1.49205910 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.48329874 |
| 36 | MP0001873_stomach_inflammation | 1.38959391 |
| 37 | MP0003186_abnormal_redox_activity | 1.36297023 |
| 38 | MP0001905_abnormal_dopamine_level | 1.33952541 |
| 39 | MP0005389_reproductive_system_phenotype | 1.33838158 |
| 40 | MP0008995_early_reproductive_senescence | 1.33085250 |
| 41 | MP0004885_abnormal_endolymph | 1.29923583 |
| 42 | MP0005387_immune_system_phenotype | 1.27317354 |
| 43 | MP0001790_abnormal_immune_system | 1.27317354 |
| 44 | MP0005253_abnormal_eye_physiology | 1.26582983 |
| 45 | MP0001293_anophthalmia | 1.25887682 |
| 46 | MP0002160_abnormal_reproductive_system | 1.25490461 |
| 47 | MP0000372_irregular_coat_pigmentation | 1.24980653 |
| 48 | MP0002277_abnormal_respiratory_mucosa | 1.24066290 |
| 49 | MP0001485_abnormal_pinna_reflex | 1.23563645 |
| 50 | MP0009785_altered_susceptibility_to | 1.22209475 |
| 51 | MP0001800_abnormal_humoral_immune | 1.22131165 |
| 52 | MP0002148_abnormal_hypersensitivity_rea | 1.21397439 |
| 53 | MP0005075_abnormal_melanosome_morpholog | 1.20615028 |
| 54 | MP0000685_abnormal_immune_system | 1.19672744 |
| 55 | MP0001984_abnormal_olfaction | 1.19404372 |
| 56 | MP0002272_abnormal_nervous_system | 1.14211690 |
| 57 | MP0005499_abnormal_olfactory_system | 1.13348775 |
| 58 | MP0005394_taste/olfaction_phenotype | 1.13348775 |
| 59 | MP0003693_abnormal_embryo_hatching | 1.12863486 |
| 60 | MP0001919_abnormal_reproductive_system | 1.07556643 |
| 61 | MP0009745_abnormal_behavioral_response | 1.06553826 |
| 62 | MP0002234_abnormal_pharynx_morphology | 1.04745763 |
| 63 | MP0006035_abnormal_mitochondrial_morpho | 1.03846642 |
| 64 | MP0008775_abnormal_heart_ventricle | 1.02046045 |
| 65 | MP0009046_muscle_twitch | 1.01325224 |
| 66 | MP0009764_decreased_sensitivity_to | 1.00955710 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.98226301 |
| 68 | MP0003718_maternal_effect | 0.98225842 |
| 69 | MP0005636_abnormal_mineral_homeostasis | 0.93171174 |
| 70 | MP0004133_heterotaxia | 0.92074860 |
| 71 | MP0005332_abnormal_amino_acid | 0.90888466 |
| 72 | MP0004782_abnormal_surfactant_physiolog | 0.90338239 |
| 73 | MP0005000_abnormal_immune_tolerance | 0.90096985 |
| 74 | MP0005195_abnormal_posterior_eye | 0.85566764 |
| 75 | MP0001501_abnormal_sleep_pattern | 0.85251661 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.84194395 |
| 77 | MP0002095_abnormal_skin_pigmentation | 0.83169378 |
| 78 | MP0001970_abnormal_pain_threshold | 0.81631184 |
| 79 | MP0000049_abnormal_middle_ear | 0.81127598 |
| 80 | MP0002723_abnormal_immune_serum | 0.80221348 |
| 81 | MP0005410_abnormal_fertilization | 0.79712057 |
| 82 | MP0005377_hearing/vestibular/ear_phenot | 0.79491806 |
| 83 | MP0003878_abnormal_ear_physiology | 0.79491806 |
| 84 | MP0006276_abnormal_autonomic_nervous | 0.79057113 |
| 85 | MP0002693_abnormal_pancreas_physiology | 0.78671302 |
| 86 | MP0004215_abnormal_myocardial_fiber | 0.76783059 |
| 87 | MP0002735_abnormal_chemical_nociception | 0.76442376 |
| 88 | MP0003121_genomic_imprinting | 0.75356594 |
| 89 | MP0002938_white_spotting | 0.73031975 |
| 90 | MP0001765_abnormal_ion_homeostasis | 0.72287126 |
| 91 | MP0005085_abnormal_gallbladder_physiolo | 0.72202656 |
| 92 | MP0003880_abnormal_central_pattern | 0.71527323 |
| 93 | MP0002006_tumorigenesis | 0.71379019 |
| 94 | MP0002452_abnormal_antigen_presenting | 0.70200502 |
| 95 | MP0003283_abnormal_digestive_organ | 0.69502801 |
| 96 | MP0000230_abnormal_systemic_arterial | 0.69462303 |
| 97 | MP0002557_abnormal_social/conspecific_i | 0.67968194 |
| 98 | MP0002420_abnormal_adaptive_immunity | 0.66804160 |
| 99 | MP0001819_abnormal_immune_cell | 0.66013580 |
| 100 | MP0002210_abnormal_sex_determination | 0.65509599 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.96539312 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.43945642 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.31993035 |
| 4 | Acute encephalopathy (HP:0006846) | 4.29956943 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.22448434 |
| 6 | Increased CSF lactate (HP:0002490) | 4.19654713 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.99538229 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.84402739 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.63977919 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.52552475 |
| 11 | Abnormality of midbrain morphology (HP:0002418) | 3.46137823 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.46137823 |
| 13 | Hepatic necrosis (HP:0002605) | 3.33359258 |
| 14 | Cerebral edema (HP:0002181) | 3.21345966 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.17372577 |
| 16 | Methylmalonic acidemia (HP:0002912) | 3.17277892 |
| 17 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.12105730 |
| 18 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.85062212 |
| 19 | Macrocytic anemia (HP:0001972) | 2.84797081 |
| 20 | Increased serum lactate (HP:0002151) | 2.84251393 |
| 21 | Nephronophthisis (HP:0000090) | 2.77434243 |
| 22 | Congenital stationary night blindness (HP:0007642) | 2.76807734 |
| 23 | Reticulocytopenia (HP:0001896) | 2.75114711 |
| 24 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.74914738 |
| 25 | Optic disc pallor (HP:0000543) | 2.73388628 |
| 26 | Congenital, generalized hypertrichosis (HP:0004540) | 2.68471149 |
| 27 | Absent/shortened dynein arms (HP:0200106) | 2.67610002 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.67610002 |
| 29 | Pancreatic cysts (HP:0001737) | 2.67272890 |
| 30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.66793751 |
| 31 | Exertional dyspnea (HP:0002875) | 2.64711756 |
| 32 | Lactic acidosis (HP:0003128) | 2.63993694 |
| 33 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.60178933 |
| 34 | Abnormality of alanine metabolism (HP:0010916) | 2.60178933 |
| 35 | Hyperalaninemia (HP:0003348) | 2.60178933 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.59952497 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.59808830 |
| 38 | IgG deficiency (HP:0004315) | 2.59280257 |
| 39 | Medial flaring of the eyebrow (HP:0010747) | 2.56570974 |
| 40 | Pendular nystagmus (HP:0012043) | 2.54115498 |
| 41 | Methylmalonic aciduria (HP:0012120) | 2.49331097 |
| 42 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.43456704 |
| 43 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.43456704 |
| 44 | Respiratory failure (HP:0002878) | 2.39854052 |
| 45 | Attenuation of retinal blood vessels (HP:0007843) | 2.39607657 |
| 46 | Pancreatic fibrosis (HP:0100732) | 2.39420329 |
| 47 | Stomatitis (HP:0010280) | 2.39121593 |
| 48 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.38887241 |
| 49 | Abnormal number of erythroid precursors (HP:0012131) | 2.34377383 |
| 50 | Hyperglycinemia (HP:0002154) | 2.29687932 |
| 51 | Hypoproteinemia (HP:0003075) | 2.28832098 |
| 52 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.27808294 |
| 53 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.27808294 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.26841249 |
| 55 | Abnormality of the renal medulla (HP:0100957) | 2.26038434 |
| 56 | Lethargy (HP:0001254) | 2.23202233 |
| 57 | Abnormality of renal resorption (HP:0011038) | 2.22148548 |
| 58 | Leukodystrophy (HP:0002415) | 2.20348666 |
| 59 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.17924518 |
| 60 | True hermaphroditism (HP:0010459) | 2.16973641 |
| 61 | Exercise intolerance (HP:0003546) | 2.07727646 |
| 62 | Decreased central vision (HP:0007663) | 2.07190331 |
| 63 | Increased muscle lipid content (HP:0009058) | 2.07085315 |
| 64 | Pallor (HP:0000980) | 2.06385122 |
| 65 | Respiratory difficulties (HP:0002880) | 2.05426599 |
| 66 | Testicular atrophy (HP:0000029) | 2.04750791 |
| 67 | Type 2 muscle fiber atrophy (HP:0003554) | 2.04172042 |
| 68 | Colon cancer (HP:0003003) | 2.03669056 |
| 69 | Abnormality of serum amino acid levels (HP:0003112) | 2.02696231 |
| 70 | Abnormality of the renal cortex (HP:0011035) | 1.98858386 |
| 71 | Type II lissencephaly (HP:0007260) | 1.97755803 |
| 72 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.97400238 |
| 73 | Abnormality of vitamin B metabolism (HP:0004340) | 1.96182104 |
| 74 | Abnormality of urine glucose concentration (HP:0011016) | 1.95533870 |
| 75 | Glycosuria (HP:0003076) | 1.95533870 |
| 76 | Absent thumb (HP:0009777) | 1.95356998 |
| 77 | CNS demyelination (HP:0007305) | 1.93792514 |
| 78 | Asplenia (HP:0001746) | 1.93513865 |
| 79 | Severe combined immunodeficiency (HP:0004430) | 1.93032376 |
| 80 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.92111363 |
| 81 | Abnormal ciliary motility (HP:0012262) | 1.91308995 |
| 82 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.90872139 |
| 83 | Constricted visual fields (HP:0001133) | 1.86498822 |
| 84 | Hypomagnesemia (HP:0002917) | 1.84747708 |
| 85 | Aplastic anemia (HP:0001915) | 1.84343102 |
| 86 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.83841833 |
| 87 | Polydipsia (HP:0001959) | 1.79914202 |
| 88 | Abnormal drinking behavior (HP:0030082) | 1.79914202 |
| 89 | Keratoconus (HP:0000563) | 1.79406312 |
| 90 | Increased corneal curvature (HP:0100692) | 1.79406312 |
| 91 | Thyroiditis (HP:0100646) | 1.78576243 |
| 92 | Cleft eyelid (HP:0000625) | 1.76843363 |
| 93 | Congenital primary aphakia (HP:0007707) | 1.76281543 |
| 94 | Dicarboxylic aciduria (HP:0003215) | 1.74254970 |
| 95 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.74254970 |
| 96 | Agitation (HP:0000713) | 1.74070530 |
| 97 | Hyperphosphaturia (HP:0003109) | 1.73907096 |
| 98 | Abnormality of B cell number (HP:0010975) | 1.72091980 |
| 99 | Renal cortical cysts (HP:0000803) | 1.71817524 |
| 100 | Gait imbalance (HP:0002141) | 1.71589084 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.33411647 |
| 2 | ZAK | 3.11406185 |
| 3 | TLK1 | 3.03767823 |
| 4 | FRK | 2.86264144 |
| 5 | TXK | 2.79890359 |
| 6 | EIF2AK3 | 2.40689062 |
| 7 | NUAK1 | 2.40276192 |
| 8 | ADRBK2 | 2.36007628 |
| 9 | GRK1 | 2.33069462 |
| 10 | STK16 | 2.29498703 |
| 11 | WNK3 | 1.88032247 |
| 12 | BMPR1B | 1.71897557 |
| 13 | TIE1 | 1.70815018 |
| 14 | NME2 | 1.69061056 |
| 15 | WNK4 | 1.68610794 |
| 16 | TRIM28 | 1.64381181 |
| 17 | TEC | 1.64220874 |
| 18 | PLK4 | 1.62754803 |
| 19 | VRK2 | 1.62239085 |
| 20 | BCKDK | 1.60759587 |
| 21 | MAP3K12 | 1.59310655 |
| 22 | MST4 | 1.53490634 |
| 23 | ACVR1B | 1.51060991 |
| 24 | TAOK3 | 1.38225615 |
| 25 | PINK1 | 1.35428789 |
| 26 | NEK1 | 1.25158585 |
| 27 | OXSR1 | 1.24213941 |
| 28 | EIF2AK1 | 1.22642781 |
| 29 | VRK1 | 1.20551581 |
| 30 | PASK | 1.19545782 |
| 31 | PLK3 | 1.18091526 |
| 32 | TSSK6 | 1.15804127 |
| 33 | KIT | 1.14215253 |
| 34 | NME1 | 1.14101802 |
| 35 | PDK2 | 1.13687983 |
| 36 | ITK | 1.12619793 |
| 37 | IKBKB | 1.10127899 |
| 38 | INSRR | 1.09499993 |
| 39 | MKNK2 | 1.08457934 |
| 40 | STK39 | 1.07075804 |
| 41 | SRPK1 | 1.07036794 |
| 42 | DYRK2 | 1.05419920 |
| 43 | MAP4K1 | 1.05253913 |
| 44 | BMPR2 | 1.04573184 |
| 45 | FES | 0.96105738 |
| 46 | MAP2K6 | 0.92496420 |
| 47 | PHKG1 | 0.91144246 |
| 48 | PHKG2 | 0.91144246 |
| 49 | BUB1 | 0.81108321 |
| 50 | CDK19 | 0.81028704 |
| 51 | CDC7 | 0.78800730 |
| 52 | MYLK | 0.78758651 |
| 53 | MAP3K4 | 0.78028007 |
| 54 | ADRBK1 | 0.77038988 |
| 55 | TGFBR1 | 0.74405025 |
| 56 | MKNK1 | 0.74116532 |
| 57 | CSNK1G3 | 0.73326516 |
| 58 | RPS6KA5 | 0.72919411 |
| 59 | ERBB3 | 0.71028304 |
| 60 | BTK | 0.70791545 |
| 61 | SYK | 0.68619606 |
| 62 | EIF2AK2 | 0.68250901 |
| 63 | PRKCG | 0.67884424 |
| 64 | DAPK2 | 0.64690451 |
| 65 | CSNK1G1 | 0.63993546 |
| 66 | PLK1 | 0.63972830 |
| 67 | GRK7 | 0.63208288 |
| 68 | CSNK1G2 | 0.63089933 |
| 69 | CSF1R | 0.62979805 |
| 70 | PLK2 | 0.62978072 |
| 71 | PIK3CA | 0.62867140 |
| 72 | CSNK2A2 | 0.61935656 |
| 73 | CDK8 | 0.61920867 |
| 74 | PRKCQ | 0.61346321 |
| 75 | CSNK2A1 | 0.60646580 |
| 76 | OBSCN | 0.60333997 |
| 77 | SCYL2 | 0.59508089 |
| 78 | IKBKE | 0.58887312 |
| 79 | ATR | 0.57847996 |
| 80 | KDR | 0.57635366 |
| 81 | CAMKK2 | 0.56957962 |
| 82 | MUSK | 0.55610874 |
| 83 | TNIK | 0.54732768 |
| 84 | LCK | 0.54325617 |
| 85 | LYN | 0.51621171 |
| 86 | PRKACA | 0.51456504 |
| 87 | TAF1 | 0.50846895 |
| 88 | PBK | 0.50452784 |
| 89 | PRKCE | 0.48999416 |
| 90 | FLT3 | 0.48279345 |
| 91 | MAPK13 | 0.47742670 |
| 92 | DAPK1 | 0.46778797 |
| 93 | AURKB | 0.46176781 |
| 94 | PRKCA | 0.44527407 |
| 95 | CSNK1A1L | 0.44365450 |
| 96 | CSNK1A1 | 0.43896950 |
| 97 | MAP2K2 | 0.43023970 |
| 98 | IGF1R | 0.42011384 |
| 99 | CAMK2D | 0.40252602 |
| 100 | CAMK2A | 0.36725928 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.25637649 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.83427028 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.75086714 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.19282742 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.13413936 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.06086583 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.61794844 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.43972348 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.43238521 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.41950325 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.19715327 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17347758 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.11816404 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.01586873 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 2.00343776 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.82820925 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.80128166 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.79618179 |
| 19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.77335541 |
| 20 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.65292417 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.52450294 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.51802910 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.40954080 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.40784782 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.39180996 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.35759336 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.33443790 |
| 28 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.25328352 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.24483163 |
| 30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.22769029 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.21823182 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.21337236 |
| 33 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.19238378 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15795854 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.14505811 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.14139906 |
| 37 | DNA replication_Homo sapiens_hsa03030 | 1.08562482 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.08168045 |
| 39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.07467741 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05157590 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04417652 |
| 42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03492128 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.00484861 |
| 44 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98006685 |
| 45 | Spliceosome_Homo sapiens_hsa03040 | 0.97724849 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.89654702 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89476515 |
| 48 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.85579303 |
| 49 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.82595936 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.79688946 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.75729541 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.75641175 |
| 53 | Base excision repair_Homo sapiens_hsa03410 | 0.74257072 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.73492223 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.71318274 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.71294598 |
| 57 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.70593535 |
| 58 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.70355872 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.69282872 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66632868 |
| 61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66103443 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63122806 |
| 63 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62825383 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.62591107 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.60356734 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59612819 |
| 67 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.59233440 |
| 68 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.59071290 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59065920 |
| 70 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58996510 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58262206 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.55335004 |
| 73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.54059974 |
| 74 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.53964234 |
| 75 | Viral myocarditis_Homo sapiens_hsa05416 | 0.52970347 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.47296492 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.47232818 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47042001 |
| 79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.46774588 |
| 80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45629795 |
| 81 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44730464 |
| 82 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.44607936 |
| 83 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.44231434 |
| 84 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.42338585 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.42179924 |
| 86 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40880991 |
| 87 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38320136 |
| 88 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.36220047 |
| 89 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33276862 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.31967274 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.26025069 |
| 92 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.24537501 |
| 93 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.21867118 |
| 94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.21547392 |
| 95 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.20328956 |
| 96 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.18142339 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.17178070 |
| 98 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.15935482 |
| 99 | Sulfur relay system_Homo sapiens_hsa04122 | 0.15389704 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.15040798 |

