RPL6P29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)9.97394837
2negative regulation of catenin import into nucleus (GO:0035414)8.59368179
3positive regulation of antigen processing and presentation (GO:0002579)8.30833306
4antigen processing and presentation of endogenous antigen (GO:0019883)8.21903514
5negative regulation of granulocyte differentiation (GO:0030853)7.84958065
6peptidyl-lysine dimethylation (GO:0018027)6.30078046
7negative regulation of bone resorption (GO:0045779)6.15696224
8proteasome assembly (GO:0043248)6.06254403
9mitotic nuclear envelope reassembly (GO:0007084)6.03639573
10nuclear envelope reassembly (GO:0031468)6.03639573
11adaptation of signaling pathway (GO:0023058)6.01033711
12mannose metabolic process (GO:0006013)5.90432576
13T cell migration (GO:0072678)5.84726635
14GDP-mannose metabolic process (GO:0019673)5.81784289
15chaperone-mediated protein transport (GO:0072321)5.81594705
16regulation of antigen processing and presentation (GO:0002577)5.77150541
17positive regulation of B cell differentiation (GO:0045579)5.73162658
18positive regulation of protein export from nucleus (GO:0046827)5.44207854
19nucleoside transmembrane transport (GO:1901642)5.37479335
20ribosomal small subunit biogenesis (GO:0042274)5.33223698
21determination of adult lifespan (GO:0008340)5.09834740
22negative regulation of bone remodeling (GO:0046851)5.04492539
23peroxisome fission (GO:0016559)5.01934261
24platelet dense granule organization (GO:0060155)4.96016881
25regulation of monocyte differentiation (GO:0045655)4.93315700
26establishment of protein localization to mitochondrial membrane (GO:0090151)4.87601122
27cell proliferation in forebrain (GO:0021846)4.80285806
28negative regulation of multicellular organism growth (GO:0040015)4.64047890
29interferon-gamma production (GO:0032609)4.62078344
30regulation of synapse maturation (GO:0090128)4.55996949
31leukocyte tethering or rolling (GO:0050901)4.46072326
32positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc4.37550875
33negative regulation of tissue remodeling (GO:0034104)4.18329622
34immunoglobulin mediated immune response (GO:0016064)4.11216739
35viral transcription (GO:0019083)4.05104996
36regulation of interleukin-6 biosynthetic process (GO:0045408)4.01670165
37nucleoside transport (GO:0015858)3.99169545
38negative regulation of osteoclast differentiation (GO:0045671)3.96976486
39negative regulation of B cell proliferation (GO:0030889)3.90271241
40brown fat cell differentiation (GO:0050873)3.86837238
41macrophage activation involved in immune response (GO:0002281)3.82710903
42translational elongation (GO:0006414)3.80088743
43translational termination (GO:0006415)3.69341600
44ATP synthesis coupled proton transport (GO:0015986)3.68306930
45energy coupled proton transport, down electrochemical gradient (GO:0015985)3.68306930
46regulation of granulocyte differentiation (GO:0030852)3.63414926
47activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)3.55747453
48negative regulation of systemic arterial blood pressure (GO:0003085)3.54105061
49cellular response to exogenous dsRNA (GO:0071360)3.49883461
50ribosomal small subunit assembly (GO:0000028)3.49463473
51B cell mediated immunity (GO:0019724)3.47005413
52positive regulation by symbiont of host defense response (GO:0052509)3.42117053
53modulation by symbiont of host defense response (GO:0052031)3.42117053
54modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.42117053
55modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.42117053
56positive regulation by organism of defense response of other organism involved in symbiotic interact3.42117053
57modulation by symbiont of host immune response (GO:0052553)3.42117053
58cerebral cortex radially oriented cell migration (GO:0021799)3.37998485
59thrombin receptor signaling pathway (GO:0070493)3.37124268
60regulation of B cell differentiation (GO:0045577)3.34598528
61positive regulation of erythrocyte differentiation (GO:0045648)3.32885029
62modified amino acid transport (GO:0072337)3.27094272
63positive regulation of chemokine biosynthetic process (GO:0045080)3.26844121
64neutrophil activation involved in immune response (GO:0002283)3.21470591
65negative regulation of interleukin-6 production (GO:0032715)3.07474430
66SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.07123525
67glycerol metabolic process (GO:0006071)3.07079415
68ATP biosynthetic process (GO:0006754)3.04750145
69multi-organism transport (GO:0044766)3.04356922
70multi-organism localization (GO:1902579)3.04356922
71multi-organism intracellular transport (GO:1902583)3.04356922
72transport of virus (GO:0046794)3.04356922
73intracellular transport of virus (GO:0075733)3.04356922
74cotranslational protein targeting to membrane (GO:0006613)3.01410854
75regulation of interferon-beta biosynthetic process (GO:0045357)2.99181137
76protein targeting to ER (GO:0045047)2.97462375
77lymphocyte migration (GO:0072676)2.95379895
78heterotypic cell-cell adhesion (GO:0034113)2.87642878
79aerobic respiration (GO:0009060)2.87637716
80regulation of catenin import into nucleus (GO:0035412)2.87209127
81TOR signaling (GO:0031929)2.86549443
82phosphatidylinositol dephosphorylation (GO:0046856)2.84860853
83male meiosis I (GO:0007141)2.84712599
84establishment of protein localization to endoplasmic reticulum (GO:0072599)2.80692401
85negative regulation of smooth muscle contraction (GO:0045986)2.79843666
86cellular component biogenesis (GO:0044085)2.77462780
87phospholipid dephosphorylation (GO:0046839)2.76656350
88alditol metabolic process (GO:0019400)2.75981667
89protein localization to endoplasmic reticulum (GO:0070972)2.75374735
90cofactor transport (GO:0051181)2.75130158
91autophagic vacuole fusion (GO:0000046)2.74879261
92cellular protein complex disassembly (GO:0043624)2.73709802
93peptidyl-lysine methylation (GO:0018022)2.72960639
94mitochondrial calcium ion homeostasis (GO:0051560)2.70680497
95peptidyl-lysine trimethylation (GO:0018023)2.70607182
96cellular response to interferon-beta (GO:0035458)2.65142621
97regulation of antigen processing and presentation of peptide antigen (GO:0002583)14.3137316
98DNA strand renaturation (GO:0000733)14.1557548
99antigen processing and presentation via MHC class Ib (GO:0002475)13.6886739
100antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)10.9960910

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.41690189
2E2F7_22180533_ChIP-Seq_HELA_Human6.30799214
3RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.27263768
4ELF1_17652178_ChIP-ChIP_JURKAT_Human5.18200546
5IRF8_22096565_ChIP-ChIP_GC-B_Human4.80272271
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.08231500
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.86811561
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.21927871
9BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.20185118
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.00957948
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.81036698
12BMI1_19503595_ChIP-Seq_MEFsC_Mouse2.43574807
13EZH2_22144423_ChIP-Seq_EOC_Human2.33979913
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.09417537
15MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.04387157
16PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.97718322
17IKZF1_21737484_ChIP-ChIP_HCT116_Human1.96599564
18TP53_20018659_ChIP-ChIP_R1E_Mouse1.91826670
19KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.89817965
20KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.89817965
21KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.89817965
22TRIM28_21343339_ChIP-Seq_HEK293_Human1.84610682
23RUNX_20019798_ChIP-Seq_JUKART_Human1.81563724
24GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.80928596
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.73126257
26NOTCH1_21737748_ChIP-Seq_TLL_Human1.72977682
27JARID2_20064375_ChIP-Seq_MESCs_Mouse1.72630501
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.71798314
29ETV1_20927104_ChIP-Seq_GIST48_Human1.62195554
30GATA6_21074721_ChIP-Seq_CACO-2_Human1.51667585
31HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.50077156
32SRY_22984422_ChIP-ChIP_TESTIS_Rat1.48785799
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.48709663
34EED_16625203_ChIP-ChIP_MESCs_Mouse1.48709340
35SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.42940547
36PHF8_20622853_ChIP-Seq_HELA_Human1.40665169
37EZH2_27304074_Chip-Seq_ESCs_Mouse1.39905478
38RNF2_27304074_Chip-Seq_NSC_Mouse1.38357811
39CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.35762223
40PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.34140811
41CBX2_22325352_ChIP-Seq_293T-Rex_Human1.32572541
42RBPJ_21746931_ChIP-Seq_IB4_Human1.31273884
43ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29509080
44FLI1_27457419_Chip-Seq_LIVER_Mouse1.26204494
45RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26101346
46LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.23318250
47NCOR_22424771_ChIP-Seq_293T_Human1.21654410
48EZH2_27294783_Chip-Seq_ESCs_Mouse1.20507300
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.20281747
50SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.19852938
51EST1_17652178_ChIP-ChIP_JURKAT_Human1.15901856
52SUZ12_27294783_Chip-Seq_ESCs_Mouse1.14308777
53NANOG_20526341_ChIP-Seq_ESCs_Human1.12184918
54RNF2_27304074_Chip-Seq_ESCs_Mouse1.12040718
55CTCF_20526341_ChIP-Seq_ESCs_Human1.10225163
56JARID2_20075857_ChIP-Seq_MESCs_Mouse1.08803692
57HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.08529502
58NFYA_21822215_ChIP-Seq_K562_Human1.08137456
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.06550374
60RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.03628358
61TAF2_19829295_ChIP-Seq_ESCs_Human1.02322357
62EZH2_18974828_ChIP-Seq_MESCs_Mouse1.00992969
63RNF2_18974828_ChIP-Seq_MESCs_Mouse1.00992969
64SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.99862305
65ETS1_20019798_ChIP-Seq_JURKAT_Human0.98957721
66HNFA_21074721_ChIP-Seq_CACO-2_Human0.97661873
67PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.97573920
68CTCF_27219007_Chip-Seq_Bcells_Human0.96485991
69SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.94988927
70GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.94340267
71FOXH1_21741376_ChIP-Seq_EPCs_Human0.94192469
72STAT4_19710469_ChIP-ChIP_TH1__Mouse0.90916844
73EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.90494822
74VDR_22108803_ChIP-Seq_LS180_Human0.90045063
75EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.89128066
76RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.86671822
77TDRD3_21172665_ChIP-Seq_MCF-7_Human0.86322554
78OCT4_20526341_ChIP-Seq_ESCs_Human0.86251406
79FOXA1_27270436_Chip-Seq_PROSTATE_Human0.84359002
80FOXA1_25329375_ChIP-Seq_VCAP_Human0.84359002
81GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.84276552
82PCGF2_27294783_Chip-Seq_ESCs_Mouse0.84210302
83LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.80488086
84EGR1_23403033_ChIP-Seq_LIVER_Mouse0.80351072
85YY1_22570637_ChIP-Seq_MALME-3M_Human0.79273263
86TP53_22573176_ChIP-Seq_HFKS_Human0.79045774
87NFYB_21822215_ChIP-Seq_K562_Human0.78940657
88EGR1_19032775_ChIP-ChIP_M12_Human0.77631751
89POU5F1_16153702_ChIP-ChIP_HESCs_Human0.77150844
90NFE2_27457419_Chip-Seq_LIVER_Mouse0.75696514
91SA1_27219007_Chip-Seq_Bcells_Human0.74075059
92RAD21_21589869_ChIP-Seq_MESCs_Mouse0.73311499
93FOXH1_21741376_ChIP-Seq_ESCs_Human0.72014245
94P53_22387025_ChIP-Seq_ESCs_Mouse0.70850099
95PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.69756626
96IGF1R_20145208_ChIP-Seq_DFB_Human0.69271067
97GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.68958667
98SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.66935018
99SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.66794532
100CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.66674205

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003878_abnormal_ear_physiology7.24735548
2MP0005377_hearing/vestibular/ear_phenot7.24735548
3MP0002102_abnormal_ear_morphology6.53439625
4MP0001835_abnormal_antigen_presentation5.50853837
5MP0003879_abnormal_hair_cell4.34104886
6MP0005671_abnormal_response_to4.25145412
7MP0000685_abnormal_immune_system3.47253817
8MP0002166_altered_tumor_susceptibility3.45137849
9MP0002638_abnormal_pupillary_reflex3.00991256
10MP0002006_tumorigenesis2.80419028
11MP0001485_abnormal_pinna_reflex2.47608878
12MP0002933_joint_inflammation2.36338538
13MP0005360_urolithiasis2.20533940
14MP0003646_muscle_fatigue2.05765241
15MP0004742_abnormal_vestibular_system1.96617950
16MP0009250_abnormal_appendicular_skeleto1.87887752
17MP0004142_abnormal_muscle_tone1.83721749
18MP0001486_abnormal_startle_reflex1.71548038
19MP0001873_stomach_inflammation1.70771863
20MP0005387_immune_system_phenotype1.70149629
21MP0001790_abnormal_immune_system1.70149629
22MP0001727_abnormal_embryo_implantation1.69418376
23MP0006082_CNS_inflammation1.67630970
24MP0006072_abnormal_retinal_apoptosis1.65637544
25MP0003137_abnormal_impulse_conducting1.53381367
26MP0001986_abnormal_taste_sensitivity1.46639423
27MP0005464_abnormal_platelet_physiology1.41514043
28MP0009379_abnormal_foot_pigmentation1.29276287
29MP0002837_dystrophic_cardiac_calcinosis1.26446628
30MP0009764_decreased_sensitivity_to1.25493599
31MP0005025_abnormal_response_to1.19517888
32MP0005423_abnormal_somatic_nervous1.16840634
33MP0001440_abnormal_grooming_behavior1.09954797
34MP0003436_decreased_susceptibility_to1.09549338
35MP0008995_early_reproductive_senescence1.05289450
36MP0003866_abnormal_defecation1.02254280
37MP0003111_abnormal_nucleus_morphology0.97094690
38MP0002332_abnormal_exercise_endurance0.90027461
39MP0003195_calcinosis0.89898495
40MP0004043_abnormal_pH_regulation0.89190752
41MP0001800_abnormal_humoral_immune0.88043303
42MP0002148_abnormal_hypersensitivity_rea0.86945815
43MP0006292_abnormal_olfactory_placode0.86272356
44MP0001542_abnormal_bone_strength0.85920790
45MP0005551_abnormal_eye_electrophysiolog0.85486392
46MP0004133_heterotaxia0.85359659
47MP0002420_abnormal_adaptive_immunity0.83432473
48MP0005389_reproductive_system_phenotype0.83349006
49MP0005503_abnormal_tendon_morphology0.82224571
50MP0001819_abnormal_immune_cell0.81785307
51MP0001119_abnormal_female_reproductive0.81724482
52MP0005000_abnormal_immune_tolerance0.80389332
53MP0002160_abnormal_reproductive_system0.79379561
54MP0002419_abnormal_innate_immunity0.73331763
55MP0002452_abnormal_antigen_presenting0.72164371
56MP0002723_abnormal_immune_serum0.69299371
57MP0002272_abnormal_nervous_system0.65010507
58MP0001845_abnormal_inflammatory_respons0.64410220
59MP0010155_abnormal_intestine_physiology0.63990415
60MP0002998_abnormal_bone_remodeling0.63452859
61MP0003252_abnormal_bile_duct0.63399744
62MP0003136_yellow_coat_color0.62178057
63MP0000716_abnormal_immune_system0.61233497
64MP0002572_abnormal_emotion/affect_behav0.59895019
65MP0001501_abnormal_sleep_pattern0.59893212
66MP0004145_abnormal_muscle_electrophysio0.59573665
67MP0008877_abnormal_DNA_methylation0.58248969
68MP0005397_hematopoietic_system_phenotyp0.57102443
69MP0001545_abnormal_hematopoietic_system0.57102443
70MP0003011_delayed_dark_adaptation0.55704179
71MP0000343_altered_response_to0.53728236
72MP0002163_abnormal_gland_morphology0.53626157
73MP0002277_abnormal_respiratory_mucosa0.53603360
74MP0004019_abnormal_vitamin_homeostasis0.53547791
75MP0000678_abnormal_parathyroid_gland0.53174552
76MP0004885_abnormal_endolymph0.51582531
77MP0001905_abnormal_dopamine_level0.51033791
78MP0000026_abnormal_inner_ear0.50453989
79MP0004858_abnormal_nervous_system0.49738033
80MP0003937_abnormal_limbs/digits/tail_de0.48686549
81MP0005275_abnormal_skin_tensile0.47708885
82MP0001919_abnormal_reproductive_system0.47322223
83MP0008875_abnormal_xenobiotic_pharmacok0.47234259
84MP0008872_abnormal_physiological_respon0.46063138
85MP0009333_abnormal_splenocyte_physiolog0.45709886
86MP0002693_abnormal_pancreas_physiology0.44445599
87MP0001963_abnormal_hearing_physiology0.44395976
88MP0005410_abnormal_fertilization0.44234395
89MP0005253_abnormal_eye_physiology0.43855689
90MP0000579_abnormal_nail_morphology0.43796468
91MP0001853_heart_inflammation0.43691904
92MP0002429_abnormal_blood_cell0.43445040
93MP0000049_abnormal_middle_ear0.42853349
94MP0005332_abnormal_amino_acid0.42623021
95MP0008469_abnormal_protein_level0.42573469
96MP0001968_abnormal_touch/_nociception0.41981083
97MP0008260_abnormal_autophagy0.40936041
98MP0009785_altered_susceptibility_to0.40442073
99MP0004134_abnormal_chest_morphology0.40280987
100MP0002557_abnormal_social/conspecific_i0.40129010

Predicted human phenotypes

RankGene SetZ-score
1Elevated erythrocyte sedimentation rate (HP:0003565)8.37141331
2Large eyes (HP:0001090)7.83146643
3Nasal polyposis (HP:0100582)7.76218982
4Chronic sinusitis (HP:0011109)6.95596571
5Abnormality of the nasal mucosa (HP:0000433)6.47551522
6Muscle fiber atrophy (HP:0100295)6.11225427
7Flat capital femoral epiphysis (HP:0003370)5.52295810
8Recurrent bronchitis (HP:0002837)5.48314035
9Shawl scrotum (HP:0000049)5.30076022
10Atrioventricular block (HP:0001678)5.07025458
11Achilles tendon contracture (HP:0001771)4.82082966
12Reduced subcutaneous adipose tissue (HP:0003758)4.79784214
13Esophageal atresia (HP:0002032)4.46086901
14Abnormality of the Achilles tendon (HP:0005109)4.42837242
15Abnormality of the fingertips (HP:0001211)4.31858939
16Basal ganglia calcification (HP:0002135)3.68324993
17Respiratory difficulties (HP:0002880)3.61890583
18Abnormality of the phalanges of the 2nd finger (HP:0009541)3.55317738
19Elbow flexion contracture (HP:0002987)3.54804265
20Rib fusion (HP:0000902)3.33918823
21Global brain atrophy (HP:0002283)3.29538449
22Abnormality of macular pigmentation (HP:0008002)3.24819477
23Heart block (HP:0012722)3.20257720
24Bronchitis (HP:0012387)3.20189467
25Patent foramen ovale (HP:0001655)3.14315677
26Hypobetalipoproteinemia (HP:0003563)3.12461087
27Abnormality of the basal ganglia (HP:0002134)3.08233336
28Large earlobe (HP:0009748)3.06419224
29Acanthocytosis (HP:0001927)3.04561706
30Trismus (HP:0000211)3.03520339
31Abnormal atrioventricular conduction (HP:0005150)2.89655296
32Ectopia lentis (HP:0001083)2.85381421
33Hemiplegia (HP:0002301)2.82118120
34Flexion contracture of toe (HP:0005830)2.79721295
35Joint contractures involving the joints of the feet (HP:0100492)2.79721295
36Gastrointestinal atresia (HP:0002589)2.76520498
37Abnormality of cells of the erythroid lineage (HP:0012130)2.75335682
38Large for gestational age (HP:0001520)2.69225029
39Emphysema (HP:0002097)2.68913461
40Midline defect of the nose (HP:0004122)2.61442719
41Beaking of vertebral bodies (HP:0004568)2.59161017
42Hypergammaglobulinemia (HP:0010702)2.53964983
43Patchy hypopigmentation of hair (HP:0011365)2.53456555
44Akinesia (HP:0002304)2.43445814
45Decreased electroretinogram (ERG) amplitude (HP:0000654)2.34114973
46Neurodegeneration (HP:0002180)2.33903296
47Erythema (HP:0010783)2.33192015
48Clubbing of toes (HP:0100760)2.32568299
49Abnormality of the 2nd finger (HP:0004100)2.32128020
50Long toe (HP:0010511)2.30479802
51Hypoproteinemia (HP:0003075)2.30232632
52Trigonocephaly (HP:0000243)2.29795767
53Abnormal number of erythroid precursors (HP:0012131)2.19903066
54Increased IgM level (HP:0003496)2.16250624
55Axonal loss (HP:0003447)2.14114352
56Hypertriglyceridemia (HP:0002155)2.10755219
57Short femoral neck (HP:0100864)2.09218846
58Patellar aplasia (HP:0006443)2.05390213
59Bronchiectasis (HP:0002110)2.03654155
60Dyskinesia (HP:0100660)2.03231622
61Overlapping toe (HP:0001845)2.01965675
62Hyperglycinemia (HP:0002154)2.01566020
63Chronic otitis media (HP:0000389)10.6024616
64Microcytic anemia (HP:0001935)1.99823198
65Aplasia/Hypoplasia of the patella (HP:0006498)1.97027509
66Deep philtrum (HP:0002002)1.92230100
67Methylmalonic acidemia (HP:0002912)1.91788282
68Dysphonia (HP:0001618)1.85275041
69Prominent nose (HP:0000448)1.84562573
70Agnosia (HP:0010524)1.81029252
71Abnormality of the epiphysis of the femoral head (HP:0010574)1.80018404
72Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.79250035
73Encephalitis (HP:0002383)1.78778235
74Brushfield spots (HP:0001088)1.75554880
75Macrocytic anemia (HP:0001972)1.71073589
76Severe visual impairment (HP:0001141)1.70091416
77Aplasia/hypoplasia of the uterus (HP:0008684)1.68680958
78Fibular aplasia (HP:0002990)1.68486900
79Primary atrial arrhythmia (HP:0001692)1.66307625
80Stridor (HP:0010307)1.66144045
81Hypoplasia of the uterus (HP:0000013)1.65875663
82Turricephaly (HP:0000262)1.64882378
83Abnormality of the femoral head (HP:0003368)1.64647605
84Abnormality of femoral epiphyses (HP:0006499)1.64052337
85Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.64052337
86Abolished electroretinogram (ERG) (HP:0000550)1.63751167
87Supraventricular tachycardia (HP:0004755)1.59376233
88Abnormality of the middle phalanges of the toes (HP:0010183)1.58393482
89Abnormality of the proximal phalanges of the hand (HP:0009834)1.55456397
90Waddling gait (HP:0002515)1.54702782
91Supraventricular arrhythmia (HP:0005115)1.54302894
92Abnormality of midbrain morphology (HP:0002418)1.54154527
93Molar tooth sign on MRI (HP:0002419)1.54154527
94Wide intermamillary distance (HP:0006610)1.53429253
95Hypoplasia of the ulna (HP:0003022)1.51094933
96Flat face (HP:0012368)1.50271344
97Abnormality of the antihelix (HP:0009738)1.50137073
98Reticulocytopenia (HP:0001896)1.49817076
99Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.47780593
100Abnormality of the phalanges of the 5th finger (HP:0004213)1.47148545

Predicted kinase interactions (KEA)

RankGene SetZ-score
1GRK77.21708160
2MOS6.97935781
3TGFBR26.32361322
4STK104.08833546
5GRK53.72793523
6PDK22.48723094
7MAP3K102.27629634
8EIF2AK22.23436956
9PTK22.15734444
10KIT1.88673466
11MAP2K61.52953035
12LRRK21.48068864
13ADRBK11.41353316
14TLK11.37252304
15ERN11.36819942
16NME21.36805458
17ZAK1.36116237
18TXK1.27312726
19AURKA1.27241734
20NME11.26542746
21NUAK11.25588365
22WNK41.23229332
23PRKCG1.21941360
24LCK1.21758623
25GRK11.17789005
26HCK1.04551179
27ADRBK21.02189631
28FRK0.93014520
29CDK40.92829258
30PDK10.88857206
31PRKCD0.88652430
32DMPK0.88086636
33AKT30.87754751
34PIM10.84972792
35SYK0.83515275
36PASK0.83195738
37INSRR0.81522170
38PINK10.72665394
39BCKDK0.70737711
40MAPK130.65687579
41ABL10.64390798
42OBSCN0.64103060
43JAK10.63808968
44BRAF0.63784626
45MAP4K20.63658524
46AKT20.62577213
47PHKG10.60814647
48PHKG20.60814647
49MAPKAPK20.58781308
50MUSK0.57788501
51PLK40.56374319
52CLK10.53023814
53PRKACA0.52862791
54PKN10.52527846
55WNK30.48129474
56PAK10.47373398
57MAP3K40.45513275
58IGF1R0.44825315
59NTRK20.44358022
60MAP3K60.41272872
61TIE10.40584823
62RAF10.39985704
63FES0.39725147
64INSR0.37754356
65LYN0.36544542
66RPS6KA50.36107660
67TGFBR10.35355526
68PRKG10.34758036
69CSNK2A10.34154396
70PRKCA0.33636684
71STK390.32849051
72ROCK10.32767666
73ROCK20.29129627
74PRKCB0.28198555
75JAK20.27720911
76PRKCQ0.25361022
77MAP2K20.24874422
78MYLK0.24310540
79TAOK30.23895778
80PRKACB0.23244709
81GRK60.22984707
82MAP2K40.22154186
83MAPK150.21348360
84EPHA40.20605112
85TNIK0.19958255
86VRK10.19615093
87ILK0.19422241
88PRKACG0.18742620
89PIM20.18355711
90CAMK2A0.18217431
91STK160.18151379
92PRKCH0.16866498
93OXSR10.16839619
94TSSK60.16610599
95PRKDC0.16227889
96CSNK2A20.15874822
97AKT10.15387883
98SRC0.15197300
99MAP2K70.13682508
100SGK20.12663651

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.70008253
2Primary immunodeficiency_Homo sapiens_hsa053403.83047542
3Sulfur metabolism_Homo sapiens_hsa009203.35396218
4ABC transporters_Homo sapiens_hsa020103.18671370
5Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.53108354
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.50969699
7Histidine metabolism_Homo sapiens_hsa003402.49696272
8Proteasome_Homo sapiens_hsa030502.36559138
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.34357650
10Basal transcription factors_Homo sapiens_hsa030222.23196503
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.11507276
12Regulation of autophagy_Homo sapiens_hsa041402.08889080
13beta-Alanine metabolism_Homo sapiens_hsa004102.08600042
14Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.02067903
15Antigen processing and presentation_Homo sapiens_hsa046121.87967288
16Cardiac muscle contraction_Homo sapiens_hsa042601.77750802
17Dilated cardiomyopathy_Homo sapiens_hsa054141.76527679
18Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.63031255
19Linoleic acid metabolism_Homo sapiens_hsa005911.56659303
20Allograft rejection_Homo sapiens_hsa053301.55478522
21Autoimmune thyroid disease_Homo sapiens_hsa053201.51335812
22Graft-versus-host disease_Homo sapiens_hsa053321.49627575
23Type I diabetes mellitus_Homo sapiens_hsa049401.42688472
24Asthma_Homo sapiens_hsa053101.38595212
25Oxidative phosphorylation_Homo sapiens_hsa001901.35655352
26Arginine and proline metabolism_Homo sapiens_hsa003301.31993845
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.22717583
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.20247724
29alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.19491745
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.19093446
31Vitamin digestion and absorption_Homo sapiens_hsa049771.18157250
32Salivary secretion_Homo sapiens_hsa049701.14275226
33Retinol metabolism_Homo sapiens_hsa008301.13288358
34Parkinsons disease_Homo sapiens_hsa050121.11737989
35Hematopoietic cell lineage_Homo sapiens_hsa046401.08380922
36Mineral absorption_Homo sapiens_hsa049781.04344210
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.00353850
38Bile secretion_Homo sapiens_hsa049760.98589640
39Herpes simplex infection_Homo sapiens_hsa051680.96341308
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.95252723
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.93281268
42Fructose and mannose metabolism_Homo sapiens_hsa000510.93046211
43Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.92433983
44Caffeine metabolism_Homo sapiens_hsa002320.92266543
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.90999692
46Phototransduction_Homo sapiens_hsa047440.90973403
47Huntingtons disease_Homo sapiens_hsa050160.90075483
48Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.86411751
49Nitrogen metabolism_Homo sapiens_hsa009100.86375364
50Peroxisome_Homo sapiens_hsa041460.86066812
51Tyrosine metabolism_Homo sapiens_hsa003500.85701253
52Chemical carcinogenesis_Homo sapiens_hsa052040.84347251
53Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84344430
54Protein digestion and absorption_Homo sapiens_hsa049740.83538256
55ECM-receptor interaction_Homo sapiens_hsa045120.83314094
56Alzheimers disease_Homo sapiens_hsa050100.81151651
57Fat digestion and absorption_Homo sapiens_hsa049750.80052156
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.79792212
59Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.79080649
60Viral myocarditis_Homo sapiens_hsa054160.76494357
61Propanoate metabolism_Homo sapiens_hsa006400.76390293
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72677089
63RNA degradation_Homo sapiens_hsa030180.70956749
64Systemic lupus erythematosus_Homo sapiens_hsa053220.69578140
65Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69540438
66Gastric acid secretion_Homo sapiens_hsa049710.68874097
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.62921898
68Insulin secretion_Homo sapiens_hsa049110.61872639
69Protein export_Homo sapiens_hsa030600.61144859
70Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.60313216
71Thyroid hormone synthesis_Homo sapiens_hsa049180.59116913
72Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57729428
73Taste transduction_Homo sapiens_hsa047420.57560962
74Phagosome_Homo sapiens_hsa041450.54836272
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53178348
76Arachidonic acid metabolism_Homo sapiens_hsa005900.50884566
77Olfactory transduction_Homo sapiens_hsa047400.50104352
78Fatty acid degradation_Homo sapiens_hsa000710.48679752
79Tryptophan metabolism_Homo sapiens_hsa003800.46644027
80Nicotine addiction_Homo sapiens_hsa050330.45120352
81Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.45034389
82cAMP signaling pathway_Homo sapiens_hsa040240.39139812
83Glycerolipid metabolism_Homo sapiens_hsa005610.38676430
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38589871
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36279494
86Inositol phosphate metabolism_Homo sapiens_hsa005620.35876972
87Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.35822192
88Selenocompound metabolism_Homo sapiens_hsa004500.35780845
89Renin secretion_Homo sapiens_hsa049240.35106228
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.34893338
91Ether lipid metabolism_Homo sapiens_hsa005650.34501911
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.34354817
93Pancreatic secretion_Homo sapiens_hsa049720.33491785
94Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.31254672
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.28098102
96Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.28026280
97Metabolic pathways_Homo sapiens_hsa011000.26658233
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26645881
99Malaria_Homo sapiens_hsa051440.24808751
100RNA polymerase_Homo sapiens_hsa030200.21436966

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