

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 8.98014188 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 8.78527496 |
| 3 | translational termination (GO:0006415) | 8.59054045 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 7.89586630 |
| 5 | maturation of SSU-rRNA (GO:0030490) | 7.80871981 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 7.31712649 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 7.25721587 |
| 8 | translational elongation (GO:0006414) | 7.23300104 |
| 9 | protein targeting to ER (GO:0045047) | 7.19502406 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.90120718 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 6.75941625 |
| 12 | cellular protein complex disassembly (GO:0043624) | 6.60196172 |
| 13 | viral life cycle (GO:0019058) | 6.38724589 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.35820974 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 6.35820974 |
| 16 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.35725775 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 6.26487633 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.06555638 |
| 19 | translational initiation (GO:0006413) | 5.72463109 |
| 20 | protein complex disassembly (GO:0043241) | 5.64312688 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.56662258 |
| 22 | macromolecular complex disassembly (GO:0032984) | 5.35391284 |
| 23 | behavioral response to nicotine (GO:0035095) | 5.04232191 |
| 24 | protein targeting to membrane (GO:0006612) | 4.91287364 |
| 25 | ribosomal large subunit biogenesis (GO:0042273) | 4.71197122 |
| 26 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.54774763 |
| 27 | translation (GO:0006412) | 4.52768140 |
| 28 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.44784649 |
| 29 | protein neddylation (GO:0045116) | 4.40663641 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.35287933 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 4.35287933 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.35287933 |
| 33 | respiratory electron transport chain (GO:0022904) | 4.35068352 |
| 34 | mRNA catabolic process (GO:0006402) | 4.33593106 |
| 35 | electron transport chain (GO:0022900) | 4.30551491 |
| 36 | protein complex biogenesis (GO:0070271) | 4.15903364 |
| 37 | RNA catabolic process (GO:0006401) | 3.88111305 |
| 38 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.87254371 |
| 39 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.87254371 |
| 40 | GTP biosynthetic process (GO:0006183) | 3.84744235 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.82980619 |
| 42 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.80784671 |
| 43 | cellular component biogenesis (GO:0044085) | 3.74727076 |
| 44 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.73024938 |
| 45 | nonmotile primary cilium assembly (GO:0035058) | 3.71543496 |
| 46 | ATP biosynthetic process (GO:0006754) | 3.69324108 |
| 47 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.68539890 |
| 48 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.50407885 |
| 49 | neuron fate determination (GO:0048664) | 3.42340463 |
| 50 | establishment of protein localization to membrane (GO:0090150) | 3.39517892 |
| 51 | hydrogen ion transmembrane transport (GO:1902600) | 3.38917261 |
| 52 | UTP biosynthetic process (GO:0006228) | 3.34034042 |
| 53 | somite development (GO:0061053) | 3.30051043 |
| 54 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.25641715 |
| 55 | protein targeting (GO:0006605) | 3.24843092 |
| 56 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.20569171 |
| 57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.19616819 |
| 58 | UTP metabolic process (GO:0046051) | 3.06649947 |
| 59 | establishment of protein localization to organelle (GO:0072594) | 3.05382104 |
| 60 | proton transport (GO:0015992) | 3.05320847 |
| 61 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.03480058 |
| 62 | hydrogen transport (GO:0006818) | 2.99611595 |
| 63 | rRNA processing (GO:0006364) | 2.95771783 |
| 64 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.92957458 |
| 65 | termination of RNA polymerase III transcription (GO:0006386) | 2.92957458 |
| 66 | rRNA metabolic process (GO:0016072) | 2.90479363 |
| 67 | cell proliferation in forebrain (GO:0021846) | 2.90380712 |
| 68 | tongue development (GO:0043586) | 2.89038777 |
| 69 | epithelial cilium movement (GO:0003351) | 2.84015381 |
| 70 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.83798231 |
| 71 | intracellular protein transmembrane import (GO:0044743) | 2.80994273 |
| 72 | negative regulation of appetite (GO:0032099) | 2.72881637 |
| 73 | negative regulation of response to food (GO:0032096) | 2.72881637 |
| 74 | protein localization to membrane (GO:0072657) | 2.71412887 |
| 75 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.70445888 |
| 76 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.70445888 |
| 77 | thalamus development (GO:0021794) | 2.68270539 |
| 78 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.68252652 |
| 79 | DNA deamination (GO:0045006) | 2.66996743 |
| 80 | axonemal dynein complex assembly (GO:0070286) | 2.66944363 |
| 81 | regulation of microtubule-based movement (GO:0060632) | 2.66437913 |
| 82 | CTP biosynthetic process (GO:0006241) | 2.63300482 |
| 83 | CTP metabolic process (GO:0046036) | 2.63300482 |
| 84 | intraciliary transport (GO:0042073) | 2.62784816 |
| 85 | inner mitochondrial membrane organization (GO:0007007) | 2.62633358 |
| 86 | rRNA modification (GO:0000154) | 2.60514577 |
| 87 | regulation of cilium movement (GO:0003352) | 2.60224562 |
| 88 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.57965722 |
| 89 | synaptic transmission, cholinergic (GO:0007271) | 2.57008488 |
| 90 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.56742971 |
| 91 | establishment of protein localization to mitochondrion (GO:0072655) | 2.56434570 |
| 92 | positive regulation of respiratory burst (GO:0060267) | 2.54067183 |
| 93 | protein targeting to mitochondrion (GO:0006626) | 2.51826987 |
| 94 | limb development (GO:0060173) | 2.51037517 |
| 95 | appendage development (GO:0048736) | 2.51037517 |
| 96 | respiratory chain complex IV assembly (GO:0008535) | 2.49066621 |
| 97 | negative regulation of telomere maintenance (GO:0032205) | 2.48348036 |
| 98 | pattern specification involved in kidney development (GO:0061004) | 2.47860403 |
| 99 | segment specification (GO:0007379) | 2.44997753 |
| 100 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.43944419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.52478725 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.97629652 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.36163212 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.27970135 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.22461760 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.05333227 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78355966 |
| 8 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.50981093 |
| 9 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.41992193 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.39338013 |
| 11 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.34553378 |
| 12 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.13478297 |
| 13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.12040883 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.01477903 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.97240644 |
| 16 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.95303902 |
| 17 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.91589681 |
| 18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.89477500 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89058066 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 1.88829091 |
| 21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.85595937 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.82369950 |
| 23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.79961957 |
| 24 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.79522396 |
| 25 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.70640172 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.68056912 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.66297359 |
| 28 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.65767395 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65109609 |
| 30 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.64157454 |
| 31 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.61782798 |
| 32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.61249040 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.56153132 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.53041884 |
| 35 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50613922 |
| 36 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.48190461 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.46615309 |
| 38 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.43946153 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.43186792 |
| 40 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.42788192 |
| 41 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.40976717 |
| 42 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.40419476 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.37533377 |
| 44 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.37258005 |
| 45 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36836654 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34680100 |
| 47 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34060784 |
| 48 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.32470505 |
| 49 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.28462367 |
| 50 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.27965983 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.27728777 |
| 52 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.26869234 |
| 53 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25794133 |
| 54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.24778610 |
| 55 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.24499029 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24239435 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.22986006 |
| 58 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.21630078 |
| 59 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.21274668 |
| 60 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.18433260 |
| 61 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.18063911 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14330400 |
| 63 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.13292738 |
| 64 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.13292738 |
| 65 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.13086572 |
| 66 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.12928956 |
| 67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11874322 |
| 68 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11572830 |
| 69 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09842775 |
| 70 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.07726625 |
| 71 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.07001634 |
| 72 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.06406456 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05582013 |
| 74 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.05324307 |
| 75 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.04619547 |
| 76 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.02883644 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 1.00522232 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 1.00068746 |
| 79 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.99963859 |
| 80 | P300_19829295_ChIP-Seq_ESCs_Human | 0.97417652 |
| 81 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.96533478 |
| 82 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.95992980 |
| 83 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.94575203 |
| 84 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.94280066 |
| 85 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.94125098 |
| 86 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.93726641 |
| 87 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.92291869 |
| 88 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.91849530 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90900183 |
| 90 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.90882149 |
| 91 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.90654155 |
| 92 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.90015775 |
| 93 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89990525 |
| 94 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.89925483 |
| 95 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.89432418 |
| 96 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.89220813 |
| 97 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87952190 |
| 98 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.87952190 |
| 99 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.87916139 |
| 100 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.87407375 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.44578130 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.00599394 |
| 3 | MP0003122_maternal_imprinting | 2.56262802 |
| 4 | MP0003136_yellow_coat_color | 2.54935365 |
| 5 | MP0004142_abnormal_muscle_tone | 2.45687026 |
| 6 | MP0008789_abnormal_olfactory_epithelium | 2.42533537 |
| 7 | MP0010030_abnormal_orbit_morphology | 2.38229810 |
| 8 | MP0003787_abnormal_imprinting | 2.29783464 |
| 9 | MP0002102_abnormal_ear_morphology | 2.19975926 |
| 10 | MP0003646_muscle_fatigue | 2.11883676 |
| 11 | MP0005499_abnormal_olfactory_system | 2.09284428 |
| 12 | MP0005394_taste/olfaction_phenotype | 2.09284428 |
| 13 | MP0001529_abnormal_vocalization | 2.05136380 |
| 14 | MP0001293_anophthalmia | 1.97897705 |
| 15 | MP0002938_white_spotting | 1.94860513 |
| 16 | MP0002163_abnormal_gland_morphology | 1.94128631 |
| 17 | MP0002837_dystrophic_cardiac_calcinosis | 1.88553430 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.87645215 |
| 19 | MP0000049_abnormal_middle_ear | 1.82515934 |
| 20 | MP0000778_abnormal_nervous_system | 1.79882364 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 1.79089828 |
| 22 | MP0003121_genomic_imprinting | 1.70356652 |
| 23 | MP0001485_abnormal_pinna_reflex | 1.68388945 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.65579847 |
| 25 | MP0004742_abnormal_vestibular_system | 1.64086875 |
| 26 | MP0002653_abnormal_ependyma_morphology | 1.62366059 |
| 27 | MP0004885_abnormal_endolymph | 1.60573806 |
| 28 | MP0000566_synostosis | 1.56009263 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.54318872 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.52642661 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.51998268 |
| 32 | MP0002638_abnormal_pupillary_reflex | 1.47843507 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.47692259 |
| 34 | MP0003283_abnormal_digestive_organ | 1.42848586 |
| 35 | MP0003011_delayed_dark_adaptation | 1.39800854 |
| 36 | MP0001984_abnormal_olfaction | 1.39790753 |
| 37 | MP0009053_abnormal_anal_canal | 1.39300085 |
| 38 | MP0005377_hearing/vestibular/ear_phenot | 1.39197088 |
| 39 | MP0003878_abnormal_ear_physiology | 1.39197088 |
| 40 | MP0002272_abnormal_nervous_system | 1.38636434 |
| 41 | MP0002160_abnormal_reproductive_system | 1.38379510 |
| 42 | MP0005423_abnormal_somatic_nervous | 1.36874649 |
| 43 | MP0005379_endocrine/exocrine_gland_phen | 1.36154186 |
| 44 | MP0001348_abnormal_lacrimal_gland | 1.33498340 |
| 45 | MP0003123_paternal_imprinting | 1.29916834 |
| 46 | MP0002736_abnormal_nociception_after | 1.27028399 |
| 47 | MP0001968_abnormal_touch/_nociception | 1.26042503 |
| 48 | MP0003938_abnormal_ear_development | 1.25047897 |
| 49 | MP0003880_abnormal_central_pattern | 1.24136551 |
| 50 | MP0001440_abnormal_grooming_behavior | 1.23205006 |
| 51 | MP0008872_abnormal_physiological_respon | 1.20990291 |
| 52 | MP0001905_abnormal_dopamine_level | 1.18527817 |
| 53 | MP0002557_abnormal_social/conspecific_i | 1.15598491 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.14503305 |
| 55 | MP0003937_abnormal_limbs/digits/tail_de | 1.14410052 |
| 56 | MP0002234_abnormal_pharynx_morphology | 1.13904173 |
| 57 | MP0004133_heterotaxia | 1.13520022 |
| 58 | MP0000026_abnormal_inner_ear | 1.12228869 |
| 59 | MP0005389_reproductive_system_phenotype | 1.09476815 |
| 60 | MP0005195_abnormal_posterior_eye | 1.09309351 |
| 61 | MP0003567_abnormal_fetal_cardiomyocyte | 1.08870541 |
| 62 | MP0004145_abnormal_muscle_electrophysio | 1.08631901 |
| 63 | MP0005253_abnormal_eye_physiology | 1.08369597 |
| 64 | MP0009745_abnormal_behavioral_response | 1.01619966 |
| 65 | MP0002233_abnormal_nose_morphology | 1.01394584 |
| 66 | MP0001970_abnormal_pain_threshold | 1.01058597 |
| 67 | MP0000955_abnormal_spinal_cord | 0.99067643 |
| 68 | MP0003119_abnormal_digestive_system | 0.98401737 |
| 69 | MP0002095_abnormal_skin_pigmentation | 0.98281539 |
| 70 | MP0002752_abnormal_somatic_nervous | 0.97632402 |
| 71 | MP0003186_abnormal_redox_activity | 0.96951715 |
| 72 | MP0002572_abnormal_emotion/affect_behav | 0.96323332 |
| 73 | MP0002733_abnormal_thermal_nociception | 0.96323096 |
| 74 | MP0001486_abnormal_startle_reflex | 0.96014522 |
| 75 | MP0002184_abnormal_innervation | 0.95216491 |
| 76 | MP0001986_abnormal_taste_sensitivity | 0.94827272 |
| 77 | MP0002734_abnormal_mechanical_nocicepti | 0.93101271 |
| 78 | MP0002735_abnormal_chemical_nociception | 0.90486005 |
| 79 | MP0003635_abnormal_synaptic_transmissio | 0.88555710 |
| 80 | MP0001286_abnormal_eye_development | 0.86119968 |
| 81 | MP0002063_abnormal_learning/memory/cond | 0.86065474 |
| 82 | MP0002210_abnormal_sex_determination | 0.82450148 |
| 83 | MP0002067_abnormal_sensory_capabilities | 0.82399361 |
| 84 | MP0009046_muscle_twitch | 0.81758301 |
| 85 | MP0008995_early_reproductive_senescence | 0.81002889 |
| 86 | MP0002064_seizures | 0.79854296 |
| 87 | MP0001963_abnormal_hearing_physiology | 0.78697649 |
| 88 | MP0008775_abnormal_heart_ventricle | 0.78346904 |
| 89 | MP0005391_vision/eye_phenotype | 0.78333093 |
| 90 | MP0002282_abnormal_trachea_morphology | 0.78241756 |
| 91 | MP0004019_abnormal_vitamin_homeostasis | 0.76772401 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.75496350 |
| 93 | MP0002249_abnormal_larynx_morphology | 0.74627689 |
| 94 | MP0002138_abnormal_hepatobiliary_system | 0.73857588 |
| 95 | MP0001502_abnormal_circadian_rhythm | 0.73199397 |
| 96 | MP0002876_abnormal_thyroid_physiology | 0.68924294 |
| 97 | MP0003942_abnormal_urinary_system | 0.68909279 |
| 98 | MP0002928_abnormal_bile_duct | 0.68751346 |
| 99 | MP0008875_abnormal_xenobiotic_pharmacok | 0.68324591 |
| 100 | MP0002152_abnormal_brain_morphology | 0.68156091 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 6.48101647 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.45839480 |
| 3 | Abnormal number of erythroid precursors (HP:0012131) | 4.60378257 |
| 4 | Macrocytic anemia (HP:0001972) | 4.49295930 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.32472425 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.04292647 |
| 7 | Mitochondrial inheritance (HP:0001427) | 4.01215072 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.82624101 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.82624101 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.73952622 |
| 11 | Acute encephalopathy (HP:0006846) | 3.71399419 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.69148550 |
| 13 | Septo-optic dysplasia (HP:0100842) | 3.58086607 |
| 14 | Increased CSF lactate (HP:0002490) | 3.56701342 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.54064336 |
| 16 | Pancreatic fibrosis (HP:0100732) | 3.33126334 |
| 17 | Pallor (HP:0000980) | 3.27508815 |
| 18 | Hepatocellular necrosis (HP:0001404) | 3.24726068 |
| 19 | Rib fusion (HP:0000902) | 3.21380670 |
| 20 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.20006124 |
| 21 | Hepatic necrosis (HP:0002605) | 3.13683063 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 3.12944960 |
| 23 | Pancreatic cysts (HP:0001737) | 2.98382482 |
| 24 | Nephronophthisis (HP:0000090) | 2.91610635 |
| 25 | True hermaphroditism (HP:0010459) | 2.79614453 |
| 26 | Medial flaring of the eyebrow (HP:0010747) | 2.77376850 |
| 27 | Absent thumb (HP:0009777) | 2.75269836 |
| 28 | Increased intramyocellular lipid droplets (HP:0012240) | 2.70943519 |
| 29 | Cerebral edema (HP:0002181) | 2.68140709 |
| 30 | Abnormality of renal resorption (HP:0011038) | 2.64734630 |
| 31 | Sclerocornea (HP:0000647) | 2.51121449 |
| 32 | Congenital stationary night blindness (HP:0007642) | 2.48313494 |
| 33 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.48125413 |
| 34 | Colon cancer (HP:0003003) | 2.43136270 |
| 35 | Exertional dyspnea (HP:0002875) | 2.40290340 |
| 36 | Gait imbalance (HP:0002141) | 2.39460730 |
| 37 | Type II lissencephaly (HP:0007260) | 2.38305370 |
| 38 | Myokymia (HP:0002411) | 2.33758413 |
| 39 | Abnormality of the renal medulla (HP:0100957) | 2.33707667 |
| 40 | Pendular nystagmus (HP:0012043) | 2.31520435 |
| 41 | 3-Methylglutaconic aciduria (HP:0003535) | 2.31115820 |
| 42 | Abnormal ciliary motility (HP:0012262) | 2.28956853 |
| 43 | Optic nerve hypoplasia (HP:0000609) | 2.28469996 |
| 44 | Stenosis of the external auditory canal (HP:0000402) | 2.27699942 |
| 45 | Increased serum lactate (HP:0002151) | 2.26810936 |
| 46 | Anophthalmia (HP:0000528) | 2.25921704 |
| 47 | Optic disc pallor (HP:0000543) | 2.25610718 |
| 48 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.25508367 |
| 49 | Anencephaly (HP:0002323) | 2.24969638 |
| 50 | Depressed nasal ridge (HP:0000457) | 2.24559871 |
| 51 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.23633250 |
| 52 | Congenital primary aphakia (HP:0007707) | 2.22346467 |
| 53 | Abnormal biliary tract physiology (HP:0012439) | 2.21636681 |
| 54 | Bile duct proliferation (HP:0001408) | 2.21636681 |
| 55 | Hypoplasia of the pons (HP:0012110) | 2.21205147 |
| 56 | Type 2 muscle fiber atrophy (HP:0003554) | 2.20975028 |
| 57 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.20108786 |
| 58 | Absent/shortened dynein arms (HP:0200106) | 2.20108786 |
| 59 | Increased muscle lipid content (HP:0009058) | 2.19826054 |
| 60 | Asplenia (HP:0001746) | 2.19823738 |
| 61 | Growth hormone deficiency (HP:0000824) | 2.18880795 |
| 62 | Abnormality of the labia minora (HP:0012880) | 2.13427847 |
| 63 | Maternal diabetes (HP:0009800) | 2.11762104 |
| 64 | Hyperglycinemia (HP:0002154) | 2.10675351 |
| 65 | Nephrogenic diabetes insipidus (HP:0009806) | 2.10498773 |
| 66 | Absent septum pellucidum (HP:0001331) | 2.08658635 |
| 67 | Lactic acidosis (HP:0003128) | 2.08119900 |
| 68 | Respiratory difficulties (HP:0002880) | 2.08031576 |
| 69 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.07297510 |
| 70 | Cystic liver disease (HP:0006706) | 2.07191191 |
| 71 | Supernumerary spleens (HP:0009799) | 2.06129724 |
| 72 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.04949232 |
| 73 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.04949232 |
| 74 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.02328268 |
| 75 | Ectopic kidney (HP:0000086) | 1.97749879 |
| 76 | Hypoplasia of the radius (HP:0002984) | 1.96626549 |
| 77 | Glycosuria (HP:0003076) | 1.95521641 |
| 78 | Abnormality of urine glucose concentration (HP:0011016) | 1.95521641 |
| 79 | Hyperphosphaturia (HP:0003109) | 1.95092253 |
| 80 | Triphalangeal thumb (HP:0001199) | 1.94989466 |
| 81 | Abnormality of the renal cortex (HP:0011035) | 1.94682414 |
| 82 | Postaxial foot polydactyly (HP:0001830) | 1.94610963 |
| 83 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.93829387 |
| 84 | Abnormality of the pons (HP:0007361) | 1.93285477 |
| 85 | Congenital, generalized hypertrichosis (HP:0004540) | 1.92735173 |
| 86 | Muscle fiber atrophy (HP:0100295) | 1.88888010 |
| 87 | Leukodystrophy (HP:0002415) | 1.88665268 |
| 88 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.87330971 |
| 89 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.87134519 |
| 90 | Adrenal hypoplasia (HP:0000835) | 1.86797291 |
| 91 | Exercise intolerance (HP:0003546) | 1.86776075 |
| 92 | Pachygyria (HP:0001302) | 1.86246024 |
| 93 | Respiratory failure (HP:0002878) | 1.85717504 |
| 94 | Abnormality of DNA repair (HP:0003254) | 1.84232590 |
| 95 | Esophageal atresia (HP:0002032) | 1.81882826 |
| 96 | Partial duplication of thumb phalanx (HP:0009944) | 1.79565739 |
| 97 | Poor suck (HP:0002033) | 1.79551228 |
| 98 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.77656299 |
| 99 | Vaginal atresia (HP:0000148) | 1.76701915 |
| 100 | Genital tract atresia (HP:0001827) | 1.74443853 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 3.75881640 |
| 2 | VRK2 | 3.40741768 |
| 3 | STK16 | 3.36230582 |
| 4 | WNK4 | 2.98703602 |
| 5 | GRK1 | 2.91820777 |
| 6 | EPHB2 | 2.54214793 |
| 7 | DYRK2 | 2.50399278 |
| 8 | NUAK1 | 2.43432881 |
| 9 | BCKDK | 2.06056346 |
| 10 | CASK | 1.93129765 |
| 11 | TXK | 1.83407921 |
| 12 | NME1 | 1.82018426 |
| 13 | ZAK | 1.81923063 |
| 14 | ADRBK2 | 1.79310306 |
| 15 | PASK | 1.74114961 |
| 16 | VRK1 | 1.72685557 |
| 17 | CDK19 | 1.70095328 |
| 18 | TLK1 | 1.61121015 |
| 19 | WNK3 | 1.60033563 |
| 20 | BMPR1B | 1.57698695 |
| 21 | STK39 | 1.57007166 |
| 22 | LRRK2 | 1.54931073 |
| 23 | NTRK2 | 1.53329965 |
| 24 | CAMKK2 | 1.46181385 |
| 25 | MAP4K2 | 1.40153482 |
| 26 | FRK | 1.34281156 |
| 27 | PINK1 | 1.32467722 |
| 28 | TAOK3 | 1.27128928 |
| 29 | TAF1 | 1.26917028 |
| 30 | NME2 | 1.25494313 |
| 31 | PIK3CA | 1.24242796 |
| 32 | PDK2 | 1.19300564 |
| 33 | PAK3 | 1.16319484 |
| 34 | EPHA4 | 1.15345815 |
| 35 | MKNK2 | 1.13644779 |
| 36 | MARK1 | 1.07996119 |
| 37 | MAPK15 | 1.06812650 |
| 38 | CDK8 | 1.05993441 |
| 39 | CAMK1 | 1.03518746 |
| 40 | PRKCG | 1.01442204 |
| 41 | TNIK | 0.97844504 |
| 42 | MAP3K9 | 0.90402290 |
| 43 | PLK3 | 0.89942037 |
| 44 | PLK4 | 0.89133361 |
| 45 | TGFBR1 | 0.86952164 |
| 46 | TYRO3 | 0.85703359 |
| 47 | DAPK3 | 0.85362886 |
| 48 | TSSK6 | 0.84940034 |
| 49 | CAMKK1 | 0.83646273 |
| 50 | MAPK13 | 0.79730382 |
| 51 | CDC7 | 0.77398965 |
| 52 | CAMK1D | 0.77221988 |
| 53 | PHKG2 | 0.77104532 |
| 54 | PHKG1 | 0.77104532 |
| 55 | MAP3K4 | 0.75208866 |
| 56 | WNK1 | 0.74770725 |
| 57 | INSRR | 0.73387627 |
| 58 | CSNK2A2 | 0.71340709 |
| 59 | CHEK2 | 0.67410845 |
| 60 | TEC | 0.66507914 |
| 61 | NEK1 | 0.65880884 |
| 62 | AURKA | 0.64244512 |
| 63 | PRKACA | 0.64099482 |
| 64 | MAP3K12 | 0.64051898 |
| 65 | AURKB | 0.62363534 |
| 66 | MKNK1 | 0.61061855 |
| 67 | CSNK1E | 0.60748474 |
| 68 | MAP2K7 | 0.60742219 |
| 69 | KIT | 0.60136479 |
| 70 | STK11 | 0.59680934 |
| 71 | OXSR1 | 0.57895730 |
| 72 | ADRBK1 | 0.57698656 |
| 73 | MINK1 | 0.56943614 |
| 74 | PRKCQ | 0.55425572 |
| 75 | PLK2 | 0.52321947 |
| 76 | CSNK2A1 | 0.51458746 |
| 77 | CSNK1G2 | 0.44455716 |
| 78 | LIMK1 | 0.44380900 |
| 79 | FGFR2 | 0.44010166 |
| 80 | PIM2 | 0.43310676 |
| 81 | GRK5 | 0.43214724 |
| 82 | OBSCN | 0.42765124 |
| 83 | RPS6KA6 | 0.42753831 |
| 84 | CCNB1 | 0.42587318 |
| 85 | PLK1 | 0.41111675 |
| 86 | PRKCZ | 0.40382215 |
| 87 | CDK3 | 0.40061439 |
| 88 | CSNK1A1 | 0.39217013 |
| 89 | SRPK1 | 0.39076028 |
| 90 | BUB1 | 0.38882941 |
| 91 | CAMK2A | 0.36967699 |
| 92 | MAP3K11 | 0.36927549 |
| 93 | MST4 | 0.36039763 |
| 94 | RPS6KA5 | 0.35854891 |
| 95 | ILK | 0.35112549 |
| 96 | PRKCE | 0.33958135 |
| 97 | BRSK1 | 0.33380032 |
| 98 | PRKCA | 0.33125430 |
| 99 | PRKG1 | 0.32428817 |
| 100 | PNCK | 0.31152616 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.31618718 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.82003527 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.09134135 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 3.00035528 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.80810700 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.74374138 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.72736104 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.53121221 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.38170825 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.09060060 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.83579077 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68685980 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.63097355 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.56887566 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 1.56491221 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51135437 |
| 17 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48143935 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.30912715 |
| 19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.30738540 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30221349 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.21293051 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.20517212 |
| 23 | Mismatch repair_Homo sapiens_hsa03430 | 1.20201596 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.18657383 |
| 25 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.18516733 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.17123182 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.14475962 |
| 28 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.14071368 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.09658861 |
| 30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.07849071 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03066312 |
| 32 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.99054298 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 0.95564693 |
| 34 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.93911549 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 0.93233985 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.93231121 |
| 37 | Spliceosome_Homo sapiens_hsa03040 | 0.93114772 |
| 38 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.90037226 |
| 39 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89491876 |
| 40 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.86204777 |
| 41 | DNA replication_Homo sapiens_hsa03030 | 0.81359941 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.80214175 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.78291391 |
| 44 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75428099 |
| 45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.74708798 |
| 46 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.74341820 |
| 47 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73478934 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.73304813 |
| 49 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.73023495 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72021888 |
| 51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68336311 |
| 52 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.66713608 |
| 53 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66365235 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65803990 |
| 55 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.63602748 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.62749536 |
| 57 | Base excision repair_Homo sapiens_hsa03410 | 0.62416966 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.61479662 |
| 59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58444253 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58049865 |
| 61 | Morphine addiction_Homo sapiens_hsa05032 | 0.57793132 |
| 62 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.57615866 |
| 63 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.57169741 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.56713754 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56544558 |
| 66 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52060572 |
| 67 | Allograft rejection_Homo sapiens_hsa05330 | 0.51146526 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50990928 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50143199 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48502333 |
| 71 | Insulin secretion_Homo sapiens_hsa04911 | 0.48160631 |
| 72 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.47023980 |
| 73 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.46716016 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46284688 |
| 75 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.45606075 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.43816095 |
| 77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43563735 |
| 78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42819683 |
| 79 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.42174012 |
| 80 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.41436809 |
| 81 | GABAergic synapse_Homo sapiens_hsa04727 | 0.38327191 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.36167021 |
| 83 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.36000703 |
| 84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.31773423 |
| 85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.31246501 |
| 86 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.29793722 |
| 87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29561729 |
| 88 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.29560012 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28860102 |
| 90 | Axon guidance_Homo sapiens_hsa04360 | 0.28167127 |
| 91 | Cocaine addiction_Homo sapiens_hsa05030 | 0.27523600 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27230076 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26505238 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.26443638 |
| 95 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.26276843 |
| 96 | Taste transduction_Homo sapiens_hsa04742 | 0.25633125 |
| 97 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.25250382 |
| 98 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.24617859 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24547976 |
| 100 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22769673 |

