RPL6P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.05554496
2viral transcription (GO:0019083)7.84517753
3translational termination (GO:0006415)7.56239077
4ribosomal small subunit biogenesis (GO:0042274)6.73792817
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.50532772
6cotranslational protein targeting to membrane (GO:0006613)6.42679879
7protein targeting to ER (GO:0045047)6.41882077
8translational elongation (GO:0006414)6.32824827
9establishment of protein localization to endoplasmic reticulum (GO:0072599)6.12375621
10protein localization to endoplasmic reticulum (GO:0070972)6.06476598
11ribosomal large subunit biogenesis (GO:0042273)5.75822681
12ATP synthesis coupled proton transport (GO:0015986)5.74573856
13energy coupled proton transport, down electrochemical gradient (GO:0015985)5.74573856
14viral life cycle (GO:0019058)5.69147726
15cellular protein complex disassembly (GO:0043624)5.68739974
16nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.52934532
17mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.31120965
18maturation of SSU-rRNA (GO:0030490)5.21086960
19translational initiation (GO:0006413)5.07271912
20water-soluble vitamin biosynthetic process (GO:0042364)4.96948503
21protein complex disassembly (GO:0043241)4.77662835
22protein complex biogenesis (GO:0070271)4.62813215
23macromolecular complex disassembly (GO:0032984)4.57335935
24GTP biosynthetic process (GO:0006183)4.52082782
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.49810453
26NADH dehydrogenase complex assembly (GO:0010257)4.49810453
27mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.49810453
28translation (GO:0006412)4.46767534
29proteasome assembly (GO:0043248)4.37925212
30DNA deamination (GO:0045006)4.36225924
31mitochondrial respiratory chain complex assembly (GO:0033108)4.32879524
32protein targeting to membrane (GO:0006612)4.25811463
33ribonucleoprotein complex biogenesis (GO:0022613)4.19571721
34protein neddylation (GO:0045116)4.19537061
35chaperone-mediated protein transport (GO:0072321)4.19259584
36cellular component biogenesis (GO:0044085)4.11156606
37UTP biosynthetic process (GO:0006228)3.97287172
38nuclear-transcribed mRNA catabolic process (GO:0000956)3.94480739
39behavioral response to nicotine (GO:0035095)3.93315882
40UTP metabolic process (GO:0046051)3.93272428
41termination of RNA polymerase III transcription (GO:0006386)3.83815468
42transcription elongation from RNA polymerase III promoter (GO:0006385)3.83815468
43mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.79475126
44mRNA catabolic process (GO:0006402)3.74195933
45protein polyglutamylation (GO:0018095)3.66483254
46rRNA modification (GO:0000154)3.62780265
47respiratory electron transport chain (GO:0022904)3.61692596
48electron transport chain (GO:0022900)3.60765847
49purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.53415307
50epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.49810950
51purine nucleoside triphosphate biosynthetic process (GO:0009145)3.48094142
52regulation of mitotic spindle checkpoint (GO:1903504)3.46170326
53regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.46170326
54nonmotile primary cilium assembly (GO:0035058)3.42048539
55RNA catabolic process (GO:0006401)3.40018094
56exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.34610933
57nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.29423000
58ATP biosynthetic process (GO:0006754)3.22257157
59hydrogen ion transmembrane transport (GO:1902600)3.19119503
60regulation of mitochondrial translation (GO:0070129)3.18695435
61rRNA methylation (GO:0031167)3.13457441
62base-excision repair, AP site formation (GO:0006285)3.10830066
63ribonucleoside triphosphate biosynthetic process (GO:0009201)3.05835841
64rRNA processing (GO:0006364)3.05684900
65spliceosomal complex assembly (GO:0000245)3.05022696
66CTP metabolic process (GO:0046036)3.02429131
67CTP biosynthetic process (GO:0006241)3.02429131
68rRNA metabolic process (GO:0016072)2.99756919
69RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.99320728
70tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.99320728
71respiratory chain complex IV assembly (GO:0008535)2.98321711
72organelle disassembly (GO:1903008)2.92514861
73establishment of protein localization to mitochondrial membrane (GO:0090151)2.91648047
74proton transport (GO:0015992)2.90269325
75cytochrome complex assembly (GO:0017004)2.87132618
76isotype switching (GO:0045190)2.86546822
77somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.86546822
78somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.86546822
79hydrogen transport (GO:0006818)2.84206592
80pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.81807295
81guanosine-containing compound biosynthetic process (GO:1901070)2.81277002
82pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.80602140
83cell proliferation in forebrain (GO:0021846)2.80383803
84pseudouridine synthesis (GO:0001522)2.79446809
85protein targeting (GO:0006605)2.78798305
86epithelial cilium movement (GO:0003351)2.76931485
87protein peptidyl-prolyl isomerization (GO:0000413)2.75406110
88pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.74848202
89ribosome biogenesis (GO:0042254)2.73923610
90establishment of protein localization to membrane (GO:0090150)2.73678608
91retinal rod cell development (GO:0046548)2.71929297
92regulation of cilium movement (GO:0003352)2.71433638
93pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.71168616
94cardiovascular system development (GO:0072358)2.70153680
95pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.65516881
96axonemal dynein complex assembly (GO:0070286)2.64474092
97nucleoside diphosphate phosphorylation (GO:0006165)2.62786644
98regulation of immunoglobulin secretion (GO:0051023)2.61967455
99nucleoside triphosphate biosynthetic process (GO:0009142)2.61295424
100establishment of protein localization to organelle (GO:0072594)2.60938046

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.62293164
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.46925756
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.23182865
4EZH2_22144423_ChIP-Seq_EOC_Human4.16300968
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.91257888
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.74553146
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.23989869
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.02190090
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.85084833
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.76768053
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.66214473
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.53805572
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.42215027
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.41854936
15VDR_23849224_ChIP-Seq_CD4+_Human2.32107900
16ELK1_19687146_ChIP-ChIP_HELA_Human2.17798154
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.12663983
18PCGF2_27294783_Chip-Seq_NPCs_Mouse2.05884245
19VDR_22108803_ChIP-Seq_LS180_Human2.03178149
20FOXP3_21729870_ChIP-Seq_TREG_Human1.92387259
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.92005144
22TTF2_22483619_ChIP-Seq_HELA_Human1.91622859
23ZNF274_21170338_ChIP-Seq_K562_Hela1.87792448
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.76107864
25EWS_26573619_Chip-Seq_HEK293_Human1.75616215
26PCGF2_27294783_Chip-Seq_ESCs_Mouse1.74357291
27IRF1_19129219_ChIP-ChIP_H3396_Human1.73115963
28IGF1R_20145208_ChIP-Seq_DFB_Human1.61606107
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.61406352
30RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59669058
31TP53_22573176_ChIP-Seq_HFKS_Human1.58187547
32XRN2_22483619_ChIP-Seq_HELA_Human1.57636755
33MYC_19079543_ChIP-ChIP_MESCs_Mouse1.57010555
34EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.51132267
35DCP1A_22483619_ChIP-Seq_HELA_Human1.46738351
36GABP_19822575_ChIP-Seq_HepG2_Human1.41709806
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.38092554
38MYC_18940864_ChIP-ChIP_HL60_Human1.37363117
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36820703
40MYC_18358816_ChIP-ChIP_MESCs_Mouse1.36336245
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.32396221
42PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.32106893
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.30764609
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30233976
45TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.30130116
46CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.27657428
47E2F4_17652178_ChIP-ChIP_JURKAT_Human1.27131999
48THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25138092
49GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23465189
50FUS_26573619_Chip-Seq_HEK293_Human1.22270539
51CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.22174010
52MYC_19030024_ChIP-ChIP_MESCs_Mouse1.21829999
53ELK1_22589737_ChIP-Seq_MCF10A_Human1.17650064
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.16774470
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.11398295
56ETV2_25802403_ChIP-Seq_MESCs_Mouse1.10388433
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.08883484
58FOXA1_25329375_ChIP-Seq_VCAP_Human1.06817655
59FOXA1_27270436_Chip-Seq_PROSTATE_Human1.06817655
60ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05848128
61ER_23166858_ChIP-Seq_MCF-7_Human1.05443015
62SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05314973
63P300_19829295_ChIP-Seq_ESCs_Human1.04593448
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.04442225
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.03205846
66KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01019106
67POU5F1_16153702_ChIP-ChIP_HESCs_Human0.98918724
68BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97818321
69GATA3_21878914_ChIP-Seq_MCF-7_Human0.97246450
70TAF2_19829295_ChIP-Seq_ESCs_Human0.96685318
71NFE2_27457419_Chip-Seq_LIVER_Mouse0.96473373
72EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.95311860
73NCOR_22424771_ChIP-Seq_293T_Human0.93631470
74PADI4_21655091_ChIP-ChIP_MCF-7_Human0.93628803
75ERA_21632823_ChIP-Seq_H3396_Human0.93481559
76POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93052721
77AR_20517297_ChIP-Seq_VCAP_Human0.92634556
78EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.92530200
79E2F1_18555785_ChIP-Seq_MESCs_Mouse0.92255657
80MYC_19829295_ChIP-Seq_ESCs_Human0.90326612
81PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.89912837
82SUZ12_27294783_Chip-Seq_NPCs_Mouse0.89509424
83AUTS2_25519132_ChIP-Seq_293T-REX_Human0.89424914
84GATA3_21867929_ChIP-Seq_TH1_Mouse0.89118375
85NANOG_16153702_ChIP-ChIP_HESCs_Human0.87939052
86BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.87824278
87REST_21632747_ChIP-Seq_MESCs_Mouse0.86641612
88FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.85969781
89PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.85318915
90HOXB7_26014856_ChIP-Seq_BT474_Human0.84786346
91CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.84270876
92NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.82502679
93TCF4_22108803_ChIP-Seq_LS180_Human0.82444973
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.82399693
95SOX2_16153702_ChIP-ChIP_HESCs_Human0.82296564
96MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.80604924
97EED_16625203_ChIP-ChIP_MESCs_Mouse0.80352887
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.80061383
99NANOG_19829295_ChIP-Seq_ESCs_Human0.79395177
100SOX2_19829295_ChIP-Seq_ESCs_Human0.79395177

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.70408299
2MP0006292_abnormal_olfactory_placode4.42441895
3MP0003122_maternal_imprinting3.14579975
4MP0008789_abnormal_olfactory_epithelium2.87648474
5MP0006072_abnormal_retinal_apoptosis2.82823024
6MP0002653_abnormal_ependyma_morphology2.55562084
7MP0005499_abnormal_olfactory_system2.35822416
8MP0005394_taste/olfaction_phenotype2.35822416
9MP0008875_abnormal_xenobiotic_pharmacok2.26423927
10MP0001529_abnormal_vocalization2.08193550
11MP0003011_delayed_dark_adaptation2.04146006
12MP0002102_abnormal_ear_morphology2.01843387
13MP0002277_abnormal_respiratory_mucosa1.97969139
14MP0005084_abnormal_gallbladder_morpholo1.95897936
15MP0008877_abnormal_DNA_methylation1.95451832
16MP0005551_abnormal_eye_electrophysiolog1.90060960
17MP0003693_abnormal_embryo_hatching1.89220312
18MP0001968_abnormal_touch/_nociception1.80883172
19MP0003121_genomic_imprinting1.80751081
20MP0002938_white_spotting1.77669797
21MP0000049_abnormal_middle_ear1.70287078
22MP0008058_abnormal_DNA_repair1.67835353
23MP0001293_anophthalmia1.63246663
24MP0001485_abnormal_pinna_reflex1.54182211
25MP0003183_abnormal_peptide_metabolism1.52451640
26MP0003646_muscle_fatigue1.52250071
27MP0004142_abnormal_muscle_tone1.50195358
28MP0002928_abnormal_bile_duct1.49696116
29MP0002638_abnormal_pupillary_reflex1.48639243
30MP0000631_abnormal_neuroendocrine_gland1.47377781
31MP0003950_abnormal_plasma_membrane1.46017404
32MP0002163_abnormal_gland_morphology1.37147924
33MP0001905_abnormal_dopamine_level1.32677276
34MP0003787_abnormal_imprinting1.31362542
35MP0002272_abnormal_nervous_system1.31345319
36MP0005645_abnormal_hypothalamus_physiol1.30516153
37MP0002735_abnormal_chemical_nociception1.30382162
38MP0000685_abnormal_immune_system1.22550476
39MP0001986_abnormal_taste_sensitivity1.21831643
40MP0005253_abnormal_eye_physiology1.20479551
41MP0005195_abnormal_posterior_eye1.20468628
42MP0003938_abnormal_ear_development1.20363880
43MP0001835_abnormal_antigen_presentation1.19034212
44MP0005408_hypopigmentation1.18917692
45MP0002733_abnormal_thermal_nociception1.18071460
46MP0000372_irregular_coat_pigmentation1.16672580
47MP0001970_abnormal_pain_threshold1.16428617
48MP0002234_abnormal_pharynx_morphology1.12933345
49MP0002736_abnormal_nociception_after1.10882689
50MP0006276_abnormal_autonomic_nervous1.07587084
51MP0008872_abnormal_physiological_respon1.06445300
52MP0005646_abnormal_pituitary_gland1.05538150
53MP0001440_abnormal_grooming_behavior1.04762429
54MP0009745_abnormal_behavioral_response1.04231966
55MP0001984_abnormal_olfaction1.03502046
56MP0002160_abnormal_reproductive_system1.03077523
57MP0005377_hearing/vestibular/ear_phenot0.98218822
58MP0003878_abnormal_ear_physiology0.98218822
59MP0005174_abnormal_tail_pigmentation0.98002396
60MP0003567_abnormal_fetal_cardiomyocyte0.97638360
61MP0005389_reproductive_system_phenotype0.97494481
62MP0004885_abnormal_endolymph0.96230858
63MP0002876_abnormal_thyroid_physiology0.95537884
64MP0005167_abnormal_blood-brain_barrier0.95295344
65MP0002572_abnormal_emotion/affect_behav0.93390329
66MP0000427_abnormal_hair_cycle0.93268499
67MP0002734_abnormal_mechanical_nocicepti0.92493006
68MP0003806_abnormal_nucleotide_metabolis0.90815115
69MP0004145_abnormal_muscle_electrophysio0.89015660
70MP0003786_premature_aging0.87361252
71MP0000566_synostosis0.86372747
72MP0005379_endocrine/exocrine_gland_phen0.85600989
73MP0006036_abnormal_mitochondrial_physio0.83420044
74MP0003718_maternal_effect0.82956735
75MP0000778_abnormal_nervous_system0.82249291
76MP0001879_abnormal_lymphatic_vessel0.81578999
77MP0003186_abnormal_redox_activity0.81562529
78MP0005410_abnormal_fertilization0.81140154
79MP0001919_abnormal_reproductive_system0.79982881
80MP0002095_abnormal_skin_pigmentation0.78674745
81MP0005387_immune_system_phenotype0.78670431
82MP0001790_abnormal_immune_system0.78670431
83MP0002282_abnormal_trachea_morphology0.76825394
84MP0001286_abnormal_eye_development0.75826333
85MP0002752_abnormal_somatic_nervous0.71657245
86MP0003937_abnormal_limbs/digits/tail_de0.70991380
87MP0005423_abnormal_somatic_nervous0.69778679
88MP0002138_abnormal_hepatobiliary_system0.69096324
89MP0002064_seizures0.67631211
90MP0002184_abnormal_innervation0.66340110
91MP0001501_abnormal_sleep_pattern0.66298416
92MP0002210_abnormal_sex_determination0.66270967
93MP0003195_calcinosis0.65781722
94MP0005671_abnormal_response_to0.65691600
95MP0008775_abnormal_heart_ventricle0.65487659
96MP0004133_heterotaxia0.64891057
97MP0006035_abnormal_mitochondrial_morpho0.64653740
98MP0002063_abnormal_learning/memory/cond0.64606566
99MP0003635_abnormal_synaptic_transmissio0.64584962
100MP0002233_abnormal_nose_morphology0.64428815

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)5.22166360
2Abnormality of cells of the erythroid lineage (HP:0012130)4.18987276
3Reticulocytopenia (HP:0001896)4.13177873
43-Methylglutaconic aciduria (HP:0003535)4.05368149
5Macrocytic anemia (HP:0001972)4.02102543
6Increased hepatocellular lipid droplets (HP:0006565)3.89173016
7Lipid accumulation in hepatocytes (HP:0006561)3.76028568
8Absent rod-and cone-mediated responses on ERG (HP:0007688)3.68840401
9Abnormal rod and cone electroretinograms (HP:0008323)3.64845412
10Renal Fanconi syndrome (HP:0001994)3.63123013
11Mitochondrial inheritance (HP:0001427)3.55305765
12Increased IgM level (HP:0003496)3.55107252
13Molar tooth sign on MRI (HP:0002419)3.52776575
14Abnormality of midbrain morphology (HP:0002418)3.52776575
15Acute necrotizing encephalopathy (HP:0006965)3.52748030
16Abnormal number of erythroid precursors (HP:0012131)3.44565348
17Rib fusion (HP:0000902)3.18879643
18Abolished electroretinogram (ERG) (HP:0000550)3.17657623
19Pancreatic fibrosis (HP:0100732)3.14613815
20Increased CSF lactate (HP:0002490)3.07682979
21Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.98788860
22Abnormal mitochondria in muscle tissue (HP:0008316)2.96898614
23Acute encephalopathy (HP:0006846)2.96727053
24Pallor (HP:0000980)2.82337218
25Pancreatic cysts (HP:0001737)2.78739814
26Septo-optic dysplasia (HP:0100842)2.76747088
27Progressive macrocephaly (HP:0004481)2.74673241
28Congenital, generalized hypertrichosis (HP:0004540)2.72591320
29Type II lissencephaly (HP:0007260)2.68742719
30Abnormality of renal resorption (HP:0011038)2.59697988
31Exertional dyspnea (HP:0002875)2.58751778
32Medial flaring of the eyebrow (HP:0010747)2.58680047
33Hepatocellular necrosis (HP:0001404)2.56422926
34Increased intramyocellular lipid droplets (HP:0012240)2.55643411
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.50882090
36IgG deficiency (HP:0004315)2.48862657
37Abnormality of the pons (HP:0007361)2.45135655
38Abnormal number of incisors (HP:0011064)2.39841188
39Abnormal respiratory motile cilium morphology (HP:0005938)2.38826039
40Abnormal respiratory epithelium morphology (HP:0012253)2.38826039
41Abnormality of T cell physiology (HP:0011840)2.36545932
42Abnormality of the renal collecting system (HP:0004742)2.31997279
43Abnormality of the diencephalon (HP:0010662)2.31649669
44Dynein arm defect of respiratory motile cilia (HP:0012255)2.30758553
45Absent/shortened dynein arms (HP:0200106)2.30758553
46Increased serum lactate (HP:0002151)2.28803378
47Gait imbalance (HP:0002141)2.28725476
48Cerebral edema (HP:0002181)2.28618759
49True hermaphroditism (HP:0010459)2.25141709
50Absent septum pellucidum (HP:0001331)2.25043384
51Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.22217925
52Nephronophthisis (HP:0000090)2.21012843
53Congenital primary aphakia (HP:0007707)2.20172789
54Polydipsia (HP:0001959)2.18565068
55Abnormal drinking behavior (HP:0030082)2.18565068
56Increased muscle lipid content (HP:0009058)2.18414384
57Pendular nystagmus (HP:0012043)2.12155017
58Duplicated collecting system (HP:0000081)2.11456928
59Dyschromatopsia (HP:0007641)2.07227859
60Aplasia/Hypoplasia of the spleen (HP:0010451)2.05135237
61Abnormal respiratory motile cilium physiology (HP:0012261)2.05098770
62Hepatic necrosis (HP:0002605)2.04098457
63Cerebellar dysplasia (HP:0007033)2.03685141
64Asplenia (HP:0001746)2.03076584
65Congenital stationary night blindness (HP:0007642)2.01753947
66Large for gestational age (HP:0001520)2.00478904
67Optic disc pallor (HP:0000543)1.96511350
68Abnormal ciliary motility (HP:0012262)1.92305051
69Abnormality of urine glucose concentration (HP:0011016)1.91079909
70Glycosuria (HP:0003076)1.91079909
71Abnormality of DNA repair (HP:0003254)1.90090549
72Absent thumb (HP:0009777)1.89664065
73Colon cancer (HP:0003003)1.89125937
74Bony spicule pigmentary retinopathy (HP:0007737)1.87635185
75Sclerocornea (HP:0000647)1.87124044
76Cleft eyelid (HP:0000625)1.86930795
77Neutropenia (HP:0001875)1.86201316
78Abnormality of the nasal septum (HP:0000419)1.85750642
79Cerebral hypomyelination (HP:0006808)1.83820655
80Nephrogenic diabetes insipidus (HP:0009806)1.83382127
81Abnormality of the aortic arch (HP:0012303)1.81413249
82Lactic acidosis (HP:0003128)1.81172302
83Cystic liver disease (HP:0006706)1.80195973
84Elevated erythrocyte sedimentation rate (HP:0003565)1.79985496
85Poor head control (HP:0002421)1.79620891
86Hypoplastic pelvis (HP:0008839)1.79544247
87Hyperphosphaturia (HP:0003109)1.78302659
88Attenuation of retinal blood vessels (HP:0007843)1.77505782
89Aplasia/Hypoplasia of the tongue (HP:0010295)1.77087479
90Abnormality of the septum pellucidum (HP:0007375)1.76561696
91Methylmalonic acidemia (HP:0002912)1.76360519
92Poor coordination (HP:0002370)1.72961871
93Postaxial foot polydactyly (HP:0001830)1.72581829
94Exercise intolerance (HP:0003546)1.72343445
95Respiratory difficulties (HP:0002880)1.70477754
96Adrenal hypoplasia (HP:0000835)1.70023545
97Hypoplasia of the radius (HP:0002984)1.69800687
98Methylmalonic aciduria (HP:0012120)1.69372042
99Optic nerve hypoplasia (HP:0000609)1.68974714
100Type I transferrin isoform profile (HP:0003642)1.66866213

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE16.86191718
2GRK13.11591292
3BMPR1B2.88225420
4VRK22.84156017
5WNK32.55845152
6NUAK12.46238792
7TXK2.36707227
8ADRBK22.36459859
9PLK42.32071872
10TLK12.30654176
11CDK82.11718910
12DYRK21.93219235
13LRRK21.92588106
14CAMKK21.78709744
15TAF11.77368927
16STK161.70842751
17NME11.69092543
18VRK11.67595620
19ZAK1.65063013
20TEC1.62343890
21BCKDK1.58085195
22EPHB21.50549659
23MAP4K11.33742074
24MATK1.30608974
25WNK41.22583541
26NME21.22240092
27LIMK11.21015042
28MAP4K21.20831419
29PAK31.16489989
30CDK191.12332959
31CAMK11.08365715
32OXSR11.04940516
33IRAK41.04473612
34MAP3K91.01897903
35TGFBR10.98889734
36BRSK20.98007786
37FES0.95579973
38PRKD30.93610526
39TAOK30.92297068
40INSRR0.91456736
41CASK0.87478132
42GRK50.86601852
43CAMK1D0.82709924
44PASK0.81768125
45FRK0.78942627
46TNIK0.78719308
47MKNK20.72367433
48MAP3K120.71347834
49TRIM280.69230446
50SRPK10.68985358
51IKBKB0.67340192
52PLK30.67280641
53CAMKK10.66667928
54STK390.66663539
55ADRBK10.64489987
56PLK20.64261583
57DAPK20.64178812
58BTK0.64009497
59PRKCQ0.62479896
60DYRK30.61616074
61TYRO30.61551372
62MAP3K40.59799843
63PDK20.59571493
64ACVR1B0.59332534
65CAMK1G0.58089549
66CSNK2A20.56918720
67MAPK150.56863743
68PRKCG0.55174158
69AURKB0.55072921
70ATR0.54628229
71MAP2K20.53774265
72PTK2B0.51729520
73ERN10.45429659
74ITK0.42255694
75NEK20.42020405
76CHEK20.41099569
77MAP2K70.40309011
78STK40.39641600
79OBSCN0.39168770
80IGF1R0.38650417
81PRKACA0.37866842
82NTRK10.37629060
83CSNK2A10.35125695
84PIK3CG0.35122732
85MUSK0.35087816
86CSNK1G10.34671706
87PINK10.33599821
88PRKCI0.33387072
89NEK90.32869314
90LYN0.32770879
91MAPK130.32461951
92MKNK10.31426351
93CAMK40.31363426
94PRKCE0.31307067
95NTRK20.31115212
96PLK10.30272145
97NEK10.28551437
98BRSK10.28485589
99RPS6KA60.28481620
100RPS6KB20.26780124

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.93049199
2Oxidative phosphorylation_Homo sapiens_hsa001904.23694022
3Parkinsons disease_Homo sapiens_hsa050123.36797088
4RNA polymerase_Homo sapiens_hsa030202.80058940
5Proteasome_Homo sapiens_hsa030502.69248807
6Huntingtons disease_Homo sapiens_hsa050162.46424664
7Mismatch repair_Homo sapiens_hsa034302.32532356
8Alzheimers disease_Homo sapiens_hsa050102.28862133
9Nucleotide excision repair_Homo sapiens_hsa034202.12206016
10Asthma_Homo sapiens_hsa053102.08926370
11Vitamin B6 metabolism_Homo sapiens_hsa007502.08723861
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.06818549
13DNA replication_Homo sapiens_hsa030301.93124545
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.91684115
15Cardiac muscle contraction_Homo sapiens_hsa042601.88893606
16Homologous recombination_Homo sapiens_hsa034401.87583932
17Protein export_Homo sapiens_hsa030601.81593533
18One carbon pool by folate_Homo sapiens_hsa006701.78147818
19RNA degradation_Homo sapiens_hsa030181.68869978
20Linoleic acid metabolism_Homo sapiens_hsa005911.65096952
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.56381751
22Basal transcription factors_Homo sapiens_hsa030221.51953935
23Intestinal immune network for IgA production_Homo sapiens_hsa046721.51261124
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51080788
25Allograft rejection_Homo sapiens_hsa053301.49175279
26Pyrimidine metabolism_Homo sapiens_hsa002401.44883702
27Autoimmune thyroid disease_Homo sapiens_hsa053201.38854910
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.37764477
29Spliceosome_Homo sapiens_hsa030401.32814021
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27990043
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.22791925
32Fanconi anemia pathway_Homo sapiens_hsa034601.22352310
33Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.15120270
34RNA transport_Homo sapiens_hsa030131.14448712
35Caffeine metabolism_Homo sapiens_hsa002321.09848203
36Primary immunodeficiency_Homo sapiens_hsa053401.07887586
37Collecting duct acid secretion_Homo sapiens_hsa049661.03018514
38Rheumatoid arthritis_Homo sapiens_hsa053231.01267615
39Peroxisome_Homo sapiens_hsa041460.98314220
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98233173
41Purine metabolism_Homo sapiens_hsa002300.96169733
42Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.90064560
43Phototransduction_Homo sapiens_hsa047440.88933924
44Retinol metabolism_Homo sapiens_hsa008300.85962803
45Primary bile acid biosynthesis_Homo sapiens_hsa001200.85159308
46Base excision repair_Homo sapiens_hsa034100.84890345
47Tryptophan metabolism_Homo sapiens_hsa003800.82913089
48Chemical carcinogenesis_Homo sapiens_hsa052040.81989070
49Folate biosynthesis_Homo sapiens_hsa007900.79196375
50Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77611424
51Propanoate metabolism_Homo sapiens_hsa006400.77121058
52Nicotine addiction_Homo sapiens_hsa050330.76938918
53Sulfur metabolism_Homo sapiens_hsa009200.76760108
54Arachidonic acid metabolism_Homo sapiens_hsa005900.76505884
55Butanoate metabolism_Homo sapiens_hsa006500.64792959
56Metabolic pathways_Homo sapiens_hsa011000.64332392
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.63077850
58Fat digestion and absorption_Homo sapiens_hsa049750.61604814
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59997354
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59724415
61Selenocompound metabolism_Homo sapiens_hsa004500.59322673
62Type I diabetes mellitus_Homo sapiens_hsa049400.57994505
63Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.55212693
64Graft-versus-host disease_Homo sapiens_hsa053320.53930577
65Ether lipid metabolism_Homo sapiens_hsa005650.51556941
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.51481511
67Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49656680
68Fatty acid elongation_Homo sapiens_hsa000620.49501748
69Fatty acid degradation_Homo sapiens_hsa000710.48799716
70Glycerolipid metabolism_Homo sapiens_hsa005610.48658713
71Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48331523
72Maturity onset diabetes of the young_Homo sapiens_hsa049500.45417205
73Systemic lupus erythematosus_Homo sapiens_hsa053220.45217324
74Nitrogen metabolism_Homo sapiens_hsa009100.44251242
75Viral myocarditis_Homo sapiens_hsa054160.43711025
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42199035
77NF-kappa B signaling pathway_Homo sapiens_hsa040640.41467715
78Taste transduction_Homo sapiens_hsa047420.41240627
79beta-Alanine metabolism_Homo sapiens_hsa004100.40782847
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.40605195
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39171980
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.37124190
83Serotonergic synapse_Homo sapiens_hsa047260.35052340
84Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.31706084
85Pyruvate metabolism_Homo sapiens_hsa006200.31675863
86Morphine addiction_Homo sapiens_hsa050320.30880067
87Steroid biosynthesis_Homo sapiens_hsa001000.30817371
88Drug metabolism - other enzymes_Homo sapiens_hsa009830.29175121
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28185070
90Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27184108
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25017968
92Fatty acid metabolism_Homo sapiens_hsa012120.24642715
93Malaria_Homo sapiens_hsa051440.24299631
94Glutamatergic synapse_Homo sapiens_hsa047240.21703092
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.21217818
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.19198762
97Basal cell carcinoma_Homo sapiens_hsa052170.16665020
98N-Glycan biosynthesis_Homo sapiens_hsa005100.16155942
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.16136534
100Olfactory transduction_Homo sapiens_hsa047400.14577447

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »