

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 7.46797676 |
| 2 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 7.46797676 |
| 3 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 7.14909295 |
| 4 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 7.14909295 |
| 5 | isotype switching (GO:0045190) | 7.14909295 |
| 6 | ribosomal small subunit biogenesis (GO:0042274) | 7.14292134 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 6.84886874 |
| 8 | regulation of helicase activity (GO:0051095) | 6.80922269 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 6.35468271 |
| 10 | viral transcription (GO:0019083) | 6.26228035 |
| 11 | translational termination (GO:0006415) | 5.97562402 |
| 12 | determination of adult lifespan (GO:0008340) | 5.75061681 |
| 13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.41615693 |
| 14 | cotranslational protein targeting to membrane (GO:0006613) | 5.36676556 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 5.33825331 |
| 16 | protein targeting to ER (GO:0045047) | 5.29485967 |
| 17 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 5.20511428 |
| 18 | translational elongation (GO:0006414) | 5.16833151 |
| 19 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.08061526 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 4.88994158 |
| 21 | somatic diversification of immunoglobulins (GO:0016445) | 4.86863024 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.75626577 |
| 23 | ATP synthesis coupled proton transport (GO:0015986) | 4.68158472 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.68158472 |
| 25 | GTP biosynthetic process (GO:0006183) | 4.67169645 |
| 26 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 4.64701869 |
| 27 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.60902760 |
| 28 | negative regulation of DNA recombination (GO:0045910) | 4.53429734 |
| 29 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.50388059 |
| 30 | axonemal dynein complex assembly (GO:0070286) | 4.45842868 |
| 31 | translational initiation (GO:0006413) | 4.43941191 |
| 32 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.42985138 |
| 33 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.32334632 |
| 34 | viral life cycle (GO:0019058) | 4.31775802 |
| 35 | sequestering of actin monomers (GO:0042989) | 4.28204886 |
| 36 | translation (GO:0006412) | 4.21666544 |
| 37 | DNA damage response, detection of DNA damage (GO:0042769) | 4.17817349 |
| 38 | protein neddylation (GO:0045116) | 4.12085478 |
| 39 | UTP biosynthetic process (GO:0006228) | 4.04736271 |
| 40 | sulfur amino acid catabolic process (GO:0000098) | 4.03754983 |
| 41 | chaperone-mediated protein transport (GO:0072321) | 4.03356389 |
| 42 | proteasome assembly (GO:0043248) | 4.03048742 |
| 43 | protein complex disassembly (GO:0043241) | 4.00022383 |
| 44 | B cell activation involved in immune response (GO:0002312) | 3.99238181 |
| 45 | positive regulation of megakaryocyte differentiation (GO:0045654) | 3.89960393 |
| 46 | cellular component biogenesis (GO:0044085) | 3.89850737 |
| 47 | macromolecular complex disassembly (GO:0032984) | 3.85914307 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.78922917 |
| 49 | behavioral response to nicotine (GO:0035095) | 3.72216818 |
| 50 | somatic cell DNA recombination (GO:0016444) | 3.66659978 |
| 51 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 3.66659978 |
| 52 | epithelial cilium movement (GO:0003351) | 3.63575812 |
| 53 | cilium movement (GO:0003341) | 3.58117369 |
| 54 | respiratory electron transport chain (GO:0022904) | 3.56969631 |
| 55 | somatic diversification of immune receptors (GO:0002200) | 3.55179307 |
| 56 | protein targeting to membrane (GO:0006612) | 3.52280271 |
| 57 | UTP metabolic process (GO:0046051) | 3.49973731 |
| 58 | respiratory chain complex IV assembly (GO:0008535) | 3.49652013 |
| 59 | electron transport chain (GO:0022900) | 3.47662427 |
| 60 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.46758626 |
| 61 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.41668195 |
| 62 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.41268915 |
| 63 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.41268915 |
| 64 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.40981390 |
| 65 | regulation of microtubule-based movement (GO:0060632) | 3.38445904 |
| 66 | ribosome biogenesis (GO:0042254) | 3.32691396 |
| 67 | head development (GO:0060322) | 3.28952972 |
| 68 | reciprocal DNA recombination (GO:0035825) | 3.27111143 |
| 69 | reciprocal meiotic recombination (GO:0007131) | 3.27111143 |
| 70 | mRNA catabolic process (GO:0006402) | 3.24782340 |
| 71 | positive regulation of respiratory burst (GO:0060267) | 3.23040066 |
| 72 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.18159130 |
| 73 | short-term memory (GO:0007614) | 3.16165851 |
| 74 | cytochrome complex assembly (GO:0017004) | 3.13388381 |
| 75 | negative regulation of mast cell activation (GO:0033004) | 3.05295905 |
| 76 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.04871016 |
| 77 | rRNA modification (GO:0000154) | 3.00757898 |
| 78 | rRNA methylation (GO:0031167) | 3.00060499 |
| 79 | CTP metabolic process (GO:0046036) | 2.99587282 |
| 80 | CTP biosynthetic process (GO:0006241) | 2.99587282 |
| 81 | response to histamine (GO:0034776) | 2.99111892 |
| 82 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.98129836 |
| 83 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.93020759 |
| 84 | RNA catabolic process (GO:0006401) | 2.92866281 |
| 85 | retinal rod cell development (GO:0046548) | 2.92475955 |
| 86 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.92401202 |
| 87 | regulation of cilium movement (GO:0003352) | 2.92307084 |
| 88 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.92189517 |
| 89 | DNA deamination (GO:0045006) | 2.91215260 |
| 90 | positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) | 2.87773081 |
| 91 | base-excision repair, AP site formation (GO:0006285) | 2.86947674 |
| 92 | organelle disassembly (GO:1903008) | 2.85841658 |
| 93 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.85466384 |
| 94 | protein complex biogenesis (GO:0070271) | 2.81407401 |
| 95 | termination of RNA polymerase III transcription (GO:0006386) | 2.81377585 |
| 96 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.81377585 |
| 97 | hypothalamus development (GO:0021854) | 2.76482813 |
| 98 | nephron tubule morphogenesis (GO:0072078) | 2.75747108 |
| 99 | nephron epithelium morphogenesis (GO:0072088) | 2.75747108 |
| 100 | nucleotide-excision repair, DNA damage removal (GO:0000718) | 2.75289502 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 5.30621023 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.75282273 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.61224547 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.41175739 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.21383974 |
| 6 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.11091530 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.09760278 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.89689115 |
| 9 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.83809464 |
| 10 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.61491567 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.54462690 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.48942166 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25356789 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.21588077 |
| 15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.14358177 |
| 16 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.12945804 |
| 17 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.07364119 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.06319271 |
| 19 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.01351632 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.00291050 |
| 21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.91141967 |
| 22 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.90460453 |
| 23 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.88278958 |
| 24 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.84186356 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.83126068 |
| 26 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.81595550 |
| 27 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.76332759 |
| 28 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.75382205 |
| 29 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.74714270 |
| 30 | VDR_22108803_ChIP-Seq_LS180_Human | 1.72127639 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69478178 |
| 32 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.60913540 |
| 33 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.60435241 |
| 34 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.57090690 |
| 35 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.53842343 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.51497881 |
| 37 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.51305400 |
| 38 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.51077784 |
| 39 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.48972303 |
| 40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.48458725 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.45570829 |
| 42 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.45364901 |
| 43 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44895569 |
| 44 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.44198209 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.39277892 |
| 46 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.37396925 |
| 47 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.36251762 |
| 48 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.35088442 |
| 49 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.34827830 |
| 50 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.29108978 |
| 51 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28707949 |
| 52 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27753885 |
| 53 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.27423648 |
| 54 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.27405831 |
| 55 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.24847473 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.22621427 |
| 57 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.19952977 |
| 58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.19726387 |
| 59 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.17680009 |
| 60 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14906302 |
| 61 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.12652926 |
| 62 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.10366818 |
| 63 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10210072 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.09468506 |
| 65 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.08611490 |
| 66 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.08430897 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.07396476 |
| 68 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04612316 |
| 69 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04514327 |
| 70 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.03315749 |
| 71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.03255565 |
| 72 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03095048 |
| 73 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03022702 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.02992573 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.01260005 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.01260005 |
| 77 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00540539 |
| 78 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.00265226 |
| 79 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99924853 |
| 80 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.99175484 |
| 81 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.98986995 |
| 82 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96648224 |
| 83 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.95986358 |
| 84 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.95392179 |
| 85 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.94582647 |
| 86 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93040931 |
| 87 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92169371 |
| 88 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.91118197 |
| 89 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.88106114 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.87814165 |
| 91 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.86881578 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.85396593 |
| 93 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.84291160 |
| 94 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83387735 |
| 95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.83387735 |
| 96 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.82905453 |
| 97 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.82229048 |
| 98 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.81026070 |
| 99 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.80943620 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.77836506 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.74069444 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.87817690 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.30243027 |
| 4 | MP0000569_abnormal_digit_pigmentation | 3.18070305 |
| 5 | MP0001348_abnormal_lacrimal_gland | 3.15084125 |
| 6 | MP0003136_yellow_coat_color | 2.94983809 |
| 7 | MP0010030_abnormal_orbit_morphology | 2.89623428 |
| 8 | MP0001529_abnormal_vocalization | 2.70895848 |
| 9 | MP0003787_abnormal_imprinting | 2.69762492 |
| 10 | MP0003122_maternal_imprinting | 2.67911150 |
| 11 | MP0005379_endocrine/exocrine_gland_phen | 2.31372891 |
| 12 | MP0002163_abnormal_gland_morphology | 2.30275463 |
| 13 | MP0002102_abnormal_ear_morphology | 2.27458747 |
| 14 | MP0004147_increased_porphyrin_level | 2.08075840 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.05983711 |
| 16 | MP0003880_abnormal_central_pattern | 2.02817440 |
| 17 | MP0002735_abnormal_chemical_nociception | 1.89226736 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 1.86452848 |
| 19 | MP0003121_genomic_imprinting | 1.77759232 |
| 20 | MP0000685_abnormal_immune_system | 1.75706834 |
| 21 | MP0002736_abnormal_nociception_after | 1.75040782 |
| 22 | MP0004142_abnormal_muscle_tone | 1.74790460 |
| 23 | MP0002822_catalepsy | 1.73813385 |
| 24 | MP0008872_abnormal_physiological_respon | 1.72207701 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.70393166 |
| 26 | MP0001293_anophthalmia | 1.68384288 |
| 27 | MP0005394_taste/olfaction_phenotype | 1.66924863 |
| 28 | MP0005499_abnormal_olfactory_system | 1.66924863 |
| 29 | MP0008875_abnormal_xenobiotic_pharmacok | 1.62828304 |
| 30 | MP0005083_abnormal_biliary_tract | 1.60374886 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.54878754 |
| 32 | MP0005174_abnormal_tail_pigmentation | 1.48743948 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.48286688 |
| 34 | MP0009046_muscle_twitch | 1.46299741 |
| 35 | MP0009745_abnormal_behavioral_response | 1.43581549 |
| 36 | MP0000955_abnormal_spinal_cord | 1.38775498 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.35988791 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.33581535 |
| 39 | MP0000778_abnormal_nervous_system | 1.30660297 |
| 40 | MP0003567_abnormal_fetal_cardiomyocyte | 1.28667293 |
| 41 | MP0002272_abnormal_nervous_system | 1.25220266 |
| 42 | MP0005360_urolithiasis | 1.22968451 |
| 43 | MP0008995_early_reproductive_senescence | 1.21175195 |
| 44 | MP0003635_abnormal_synaptic_transmissio | 1.20440039 |
| 45 | MP0004859_abnormal_synaptic_plasticity | 1.20102953 |
| 46 | MP0002067_abnormal_sensory_capabilities | 1.19162070 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.18764747 |
| 48 | MP0001440_abnormal_grooming_behavior | 1.18541240 |
| 49 | MP0004811_abnormal_neuron_physiology | 1.17248520 |
| 50 | MP0002095_abnormal_skin_pigmentation | 1.13810731 |
| 51 | MP0001970_abnormal_pain_threshold | 1.13743772 |
| 52 | MP0001984_abnormal_olfaction | 1.10374717 |
| 53 | MP0005671_abnormal_response_to | 1.08696554 |
| 54 | MP0002063_abnormal_learning/memory/cond | 1.07566423 |
| 55 | MP0004381_abnormal_hair_follicle | 1.05080973 |
| 56 | MP0003878_abnormal_ear_physiology | 1.03727593 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 1.03727593 |
| 58 | MP0004133_heterotaxia | 1.02732896 |
| 59 | MP0002733_abnormal_thermal_nociception | 1.00457035 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 0.97823166 |
| 61 | MP0003123_paternal_imprinting | 0.97390916 |
| 62 | MP0004742_abnormal_vestibular_system | 0.94501017 |
| 63 | MP0002064_seizures | 0.94404501 |
| 64 | MP0003329_amyloid_beta_deposits | 0.94048071 |
| 65 | MP0001905_abnormal_dopamine_level | 0.92939367 |
| 66 | MP0002229_neurodegeneration | 0.92438328 |
| 67 | MP0001324_abnormal_eye_pigmentation | 0.90854011 |
| 68 | MP0000015_abnormal_ear_pigmentation | 0.90443818 |
| 69 | MP0005253_abnormal_eye_physiology | 0.89833109 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.88837727 |
| 71 | MP0002882_abnormal_neuron_morphology | 0.88646639 |
| 72 | MP0001286_abnormal_eye_development | 0.88259202 |
| 73 | MP0001986_abnormal_taste_sensitivity | 0.88193126 |
| 74 | MP0002557_abnormal_social/conspecific_i | 0.86229896 |
| 75 | MP0002734_abnormal_mechanical_nocicepti | 0.85170260 |
| 76 | MP0002938_white_spotting | 0.84142721 |
| 77 | MP0000639_abnormal_adrenal_gland | 0.83910434 |
| 78 | MP0002837_dystrophic_cardiac_calcinosis | 0.81667222 |
| 79 | MP0005195_abnormal_posterior_eye | 0.81395795 |
| 80 | MP0002233_abnormal_nose_morphology | 0.81142268 |
| 81 | MP0002909_abnormal_adrenal_gland | 0.80560374 |
| 82 | MP0005075_abnormal_melanosome_morpholog | 0.79738865 |
| 83 | MP0008057_abnormal_DNA_replication | 0.79378680 |
| 84 | MP0005646_abnormal_pituitary_gland | 0.78303959 |
| 85 | MP0005391_vision/eye_phenotype | 0.76891250 |
| 86 | MP0002638_abnormal_pupillary_reflex | 0.76771066 |
| 87 | MP0000049_abnormal_middle_ear | 0.76492407 |
| 88 | MP0002152_abnormal_brain_morphology | 0.75126430 |
| 89 | MP0008058_abnormal_DNA_repair | 0.74211978 |
| 90 | MP0005423_abnormal_somatic_nervous | 0.74203689 |
| 91 | MP0006072_abnormal_retinal_apoptosis | 0.73992264 |
| 92 | MP0001764_abnormal_homeostasis | 0.73645535 |
| 93 | MP0002653_abnormal_ependyma_morphology | 0.73341707 |
| 94 | MP0003937_abnormal_limbs/digits/tail_de | 0.71211422 |
| 95 | MP0002138_abnormal_hepatobiliary_system | 0.70005054 |
| 96 | MP0002572_abnormal_emotion/affect_behav | 0.67105874 |
| 97 | MP0002752_abnormal_somatic_nervous | 0.66238053 |
| 98 | MP0001502_abnormal_circadian_rhythm | 0.64407411 |
| 99 | MP0005670_abnormal_white_adipose | 0.64100572 |
| 100 | MP0003861_abnormal_nervous_system | 0.63659032 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ependymoma (HP:0002888) | 6.39415877 |
| 2 | Agnosia (HP:0010524) | 6.23707242 |
| 3 | Reticulocytopenia (HP:0001896) | 5.35931547 |
| 4 | Rhabdomyosarcoma (HP:0002859) | 4.76458843 |
| 5 | Astrocytoma (HP:0009592) | 4.39397331 |
| 6 | Abnormality of the astrocytes (HP:0100707) | 4.39397331 |
| 7 | Biliary tract neoplasm (HP:0100574) | 4.19400413 |
| 8 | Medulloblastoma (HP:0002885) | 3.76742875 |
| 9 | Neoplasm of the oral cavity (HP:0100649) | 3.56251185 |
| 10 | Stomatitis (HP:0010280) | 3.55423905 |
| 11 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.53997540 |
| 12 | Thrombocytosis (HP:0001894) | 3.41231766 |
| 13 | Glioma (HP:0009733) | 3.37525744 |
| 14 | 11 pairs of ribs (HP:0000878) | 3.36380314 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 3.35172175 |
| 16 | Neoplasm of striated muscle (HP:0009728) | 3.12391491 |
| 17 | Angiofibromas (HP:0010615) | 3.10559970 |
| 18 | Adenoma sebaceum (HP:0009720) | 3.10559970 |
| 19 | Macrocytic anemia (HP:0001972) | 2.96488652 |
| 20 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.95094255 |
| 21 | Progressive macrocephaly (HP:0004481) | 2.94892824 |
| 22 | Increased IgM level (HP:0003496) | 2.93157765 |
| 23 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.89233842 |
| 24 | Abnormal ciliary motility (HP:0012262) | 2.85971038 |
| 25 | Amaurosis fugax (HP:0100576) | 2.84227605 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.81024037 |
| 27 | Mitochondrial inheritance (HP:0001427) | 2.79831745 |
| 28 | Basal cell carcinoma (HP:0002671) | 2.73647085 |
| 29 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.72820171 |
| 30 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.72820171 |
| 31 | Increased CSF lactate (HP:0002490) | 2.71417679 |
| 32 | Acute encephalopathy (HP:0006846) | 2.71177006 |
| 33 | Increased hepatocellular lipid droplets (HP:0006565) | 2.69967808 |
| 34 | Hepatic necrosis (HP:0002605) | 2.68005608 |
| 35 | Neoplasm of the rectum (HP:0100743) | 2.63490447 |
| 36 | Hepatocellular necrosis (HP:0001404) | 2.61368382 |
| 37 | Colon cancer (HP:0003003) | 2.56973783 |
| 38 | Spontaneous abortion (HP:0005268) | 2.56765943 |
| 39 | Missing ribs (HP:0000921) | 2.55466261 |
| 40 | Cerebral hypomyelination (HP:0006808) | 2.53766818 |
| 41 | Respiratory difficulties (HP:0002880) | 2.51502462 |
| 42 | Lipid accumulation in hepatocytes (HP:0006561) | 2.44769473 |
| 43 | Pachygyria (HP:0001302) | 2.40026039 |
| 44 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.39158252 |
| 45 | Abnormality of the salivary glands (HP:0010286) | 2.38990136 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.36138759 |
| 47 | Neoplasm of the small intestine (HP:0100833) | 2.35627733 |
| 48 | Supernumerary spleens (HP:0009799) | 2.35277448 |
| 49 | Neoplasm of the liver (HP:0002896) | 2.27023990 |
| 50 | Increased intramyocellular lipid droplets (HP:0012240) | 2.25437081 |
| 51 | Abnormal biliary tract morphology (HP:0012440) | 2.24456864 |
| 52 | Renal cortical cysts (HP:0000803) | 2.19921279 |
| 53 | Short middle phalanx of the 5th finger (HP:0004220) | 2.19201252 |
| 54 | Metaphyseal dysplasia (HP:0100255) | 2.18937375 |
| 55 | Cerebral edema (HP:0002181) | 2.17815140 |
| 56 | Molar tooth sign on MRI (HP:0002419) | 2.15769354 |
| 57 | Abnormality of midbrain morphology (HP:0002418) | 2.15769354 |
| 58 | Abnormal lung lobation (HP:0002101) | 2.11076619 |
| 59 | CNS hypomyelination (HP:0003429) | 2.07654364 |
| 60 | Congenital stationary night blindness (HP:0007642) | 2.05882895 |
| 61 | Pallor (HP:0000980) | 2.04811203 |
| 62 | Myokymia (HP:0002411) | 2.00359164 |
| 63 | Birth length less than 3rd percentile (HP:0003561) | 2.00252042 |
| 64 | Optic disc pallor (HP:0000543) | 1.99725814 |
| 65 | Febrile seizures (HP:0002373) | 1.98386100 |
| 66 | Abnormality of alanine metabolism (HP:0010916) | 1.98219306 |
| 67 | Hyperalaninemia (HP:0003348) | 1.98219306 |
| 68 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.98219306 |
| 69 | Neuroblastoma (HP:0003006) | 1.97729777 |
| 70 | Primitive neuroectodermal tumor (HP:0030065) | 1.97729777 |
| 71 | Neuroblastic tumors (HP:0004376) | 1.97729777 |
| 72 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.97729777 |
| 73 | Pancreatic fibrosis (HP:0100732) | 1.97573781 |
| 74 | Polyphagia (HP:0002591) | 1.94898181 |
| 75 | Bifid tongue (HP:0010297) | 1.94541125 |
| 76 | Pancreatic cysts (HP:0001737) | 1.93935349 |
| 77 | Abnormality of the septum pellucidum (HP:0007375) | 1.91516271 |
| 78 | Renal Fanconi syndrome (HP:0001994) | 1.90018425 |
| 79 | Focal seizures (HP:0007359) | 1.89684939 |
| 80 | Anophthalmia (HP:0000528) | 1.89311690 |
| 81 | Prominent metopic ridge (HP:0005487) | 1.88364961 |
| 82 | IgA deficiency (HP:0002720) | 1.87918035 |
| 83 | Focal motor seizures (HP:0011153) | 1.84121764 |
| 84 | Absent septum pellucidum (HP:0001331) | 1.79101169 |
| 85 | Increased serum lactate (HP:0002151) | 1.78841498 |
| 86 | Partial duplication of thumb phalanx (HP:0009944) | 1.78615911 |
| 87 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.77827654 |
| 88 | Septo-optic dysplasia (HP:0100842) | 1.77688451 |
| 89 | Abnormality of the metopic suture (HP:0005556) | 1.77395515 |
| 90 | Short tibia (HP:0005736) | 1.76843322 |
| 91 | Stenosis of the external auditory canal (HP:0000402) | 1.76324734 |
| 92 | Type II lissencephaly (HP:0007260) | 1.73617141 |
| 93 | Sclerocornea (HP:0000647) | 1.73435672 |
| 94 | Increased muscle lipid content (HP:0009058) | 1.73059652 |
| 95 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.72524689 |
| 96 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.69175794 |
| 97 | Absent eyebrow (HP:0002223) | 1.68989139 |
| 98 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.68937030 |
| 99 | Exertional dyspnea (HP:0002875) | 1.68719862 |
| 100 | Neoplasm of the colon (HP:0100273) | 1.68514778 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 7.28648088 |
| 2 | PAK4 | 4.65860429 |
| 3 | WNK3 | 3.72256708 |
| 4 | MAP4K2 | 3.21214267 |
| 5 | WNK4 | 3.16217749 |
| 6 | CASK | 3.02437038 |
| 7 | TLK1 | 2.73404678 |
| 8 | SIK2 | 2.62590833 |
| 9 | MAP3K12 | 2.57556891 |
| 10 | BCR | 2.32564557 |
| 11 | PDK2 | 2.22771339 |
| 12 | FRK | 2.06853594 |
| 13 | DYRK2 | 2.04150813 |
| 14 | INSRR | 1.61683120 |
| 15 | STK39 | 1.60320164 |
| 16 | SRPK1 | 1.52243190 |
| 17 | MARK1 | 1.47698125 |
| 18 | MAP2K7 | 1.44641525 |
| 19 | TSSK6 | 1.43240429 |
| 20 | NTRK2 | 1.42008983 |
| 21 | BCKDK | 1.33601109 |
| 22 | NUAK1 | 1.29642835 |
| 23 | CCNB1 | 1.23979682 |
| 24 | PAK3 | 1.21932770 |
| 25 | PHKG2 | 1.14444822 |
| 26 | PHKG1 | 1.14444822 |
| 27 | GRK1 | 1.03678293 |
| 28 | NEK1 | 1.03269250 |
| 29 | CDK8 | 1.00347069 |
| 30 | DAPK2 | 0.97699207 |
| 31 | MAPKAPK5 | 0.89908864 |
| 32 | CSNK1G2 | 0.86738186 |
| 33 | MAP3K4 | 0.85579323 |
| 34 | TRIM28 | 0.84749634 |
| 35 | EPHA4 | 0.83408898 |
| 36 | CAMK1 | 0.82000130 |
| 37 | PIK3CA | 0.81941279 |
| 38 | MAPK13 | 0.80786726 |
| 39 | VRK1 | 0.79484106 |
| 40 | CSNK2A2 | 0.78075655 |
| 41 | BMPR1B | 0.77884884 |
| 42 | RPS6KA5 | 0.77376597 |
| 43 | CSNK1D | 0.75949808 |
| 44 | CSNK1G3 | 0.74914013 |
| 45 | NEK2 | 0.71275155 |
| 46 | PASK | 0.69836783 |
| 47 | CSNK1A1L | 0.69388488 |
| 48 | RAF1 | 0.69153562 |
| 49 | MAP2K4 | 0.68556541 |
| 50 | WNK1 | 0.66774301 |
| 51 | MKNK2 | 0.64982365 |
| 52 | MKNK1 | 0.64078004 |
| 53 | CSNK1G1 | 0.63315050 |
| 54 | CSNK1E | 0.63158372 |
| 55 | TEC | 0.58573002 |
| 56 | PLK4 | 0.58528432 |
| 57 | TAOK2 | 0.57637551 |
| 58 | ALK | 0.57252007 |
| 59 | STK4 | 0.55003864 |
| 60 | FGFR1 | 0.54945464 |
| 61 | ZAK | 0.53985065 |
| 62 | ACVR1B | 0.53033337 |
| 63 | ADRBK2 | 0.51591888 |
| 64 | PRKCG | 0.51105149 |
| 65 | TIE1 | 0.48621069 |
| 66 | RIPK4 | 0.47645868 |
| 67 | DYRK1A | 0.43391862 |
| 68 | TGFBR1 | 0.43073442 |
| 69 | CDC7 | 0.42308808 |
| 70 | IKBKB | 0.41263807 |
| 71 | ATR | 0.40117461 |
| 72 | PRKCI | 0.40053951 |
| 73 | AURKB | 0.39150983 |
| 74 | VRK2 | 0.37539932 |
| 75 | NME1 | 0.35126465 |
| 76 | MAPK12 | 0.34827960 |
| 77 | CDK5 | 0.34043139 |
| 78 | WEE1 | 0.33631242 |
| 79 | ABL2 | 0.33226994 |
| 80 | ILK | 0.31791160 |
| 81 | CSNK1A1 | 0.31303768 |
| 82 | CAMK2A | 0.31154462 |
| 83 | MAP3K11 | 0.30730510 |
| 84 | MARK2 | 0.30729394 |
| 85 | PRKACB | 0.30309212 |
| 86 | OXSR1 | 0.29756179 |
| 87 | PRKACA | 0.28581205 |
| 88 | OBSCN | 0.27652314 |
| 89 | CSNK2A1 | 0.26959404 |
| 90 | MAP3K9 | 0.26378572 |
| 91 | CHEK1 | 0.26050768 |
| 92 | PIM2 | 0.25743644 |
| 93 | DAPK3 | 0.25434032 |
| 94 | PRKCB | 0.25304773 |
| 95 | ATM | 0.25023692 |
| 96 | BUB1 | 0.24787976 |
| 97 | PLK3 | 0.24390598 |
| 98 | ADRBK1 | 0.24353539 |
| 99 | PRKAA1 | 0.24094861 |
| 100 | IKBKE | 0.23695192 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.95522485 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.01506970 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.50833802 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 3.49845056 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.39397741 |
| 6 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.85567917 |
| 7 | Nicotine addiction_Homo sapiens_hsa05033 | 2.81132152 |
| 8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.79597330 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.70688493 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48579605 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.37153824 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 2.07161256 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.04998198 |
| 14 | Asthma_Homo sapiens_hsa05310 | 2.03647925 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.03553500 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 2.01132863 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.90311383 |
| 18 | GABAergic synapse_Homo sapiens_hsa04727 | 1.79204034 |
| 19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.66535016 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.63324847 |
| 21 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.57279393 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.54631101 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.43310786 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.42959651 |
| 25 | Taste transduction_Homo sapiens_hsa04742 | 1.35753980 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34467133 |
| 27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.28559277 |
| 28 | RNA transport_Homo sapiens_hsa03013 | 1.27289250 |
| 29 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.16085322 |
| 30 | Allograft rejection_Homo sapiens_hsa05330 | 1.11467410 |
| 31 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.09475663 |
| 32 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.04421045 |
| 33 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.02371106 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 0.99088972 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.95485703 |
| 36 | Morphine addiction_Homo sapiens_hsa05032 | 0.90987516 |
| 37 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.90889230 |
| 38 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.88033952 |
| 39 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.87423663 |
| 40 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.87394056 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85991274 |
| 42 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.79521970 |
| 43 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.76561701 |
| 44 | DNA replication_Homo sapiens_hsa03030 | 0.73936857 |
| 45 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.71311165 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.70820899 |
| 47 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.70688649 |
| 48 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.70680119 |
| 49 | Axon guidance_Homo sapiens_hsa04360 | 0.67016304 |
| 50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.66980790 |
| 51 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.66436644 |
| 52 | Base excision repair_Homo sapiens_hsa03410 | 0.65557417 |
| 53 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.65459279 |
| 54 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.64924839 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63767052 |
| 56 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.63256564 |
| 57 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.62976332 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.58107138 |
| 59 | Alcoholism_Homo sapiens_hsa05034 | 0.57647833 |
| 60 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.56887379 |
| 61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56715517 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.55916762 |
| 63 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.55289730 |
| 64 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.54206379 |
| 65 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.52930815 |
| 66 | Viral myocarditis_Homo sapiens_hsa05416 | 0.52340113 |
| 67 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.46249098 |
| 68 | Cocaine addiction_Homo sapiens_hsa05030 | 0.44574868 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.43604659 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42800752 |
| 71 | Circadian entrainment_Homo sapiens_hsa04713 | 0.41545704 |
| 72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.40771826 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39825445 |
| 74 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.38620886 |
| 75 | Sulfur relay system_Homo sapiens_hsa04122 | 0.36907815 |
| 76 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.34006254 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33777654 |
| 78 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.32581655 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32456689 |
| 80 | Colorectal cancer_Homo sapiens_hsa05210 | 0.31831870 |
| 81 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29757210 |
| 82 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29436414 |
| 83 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.28901952 |
| 84 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.28351408 |
| 85 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27967026 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.27699039 |
| 87 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.27343198 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.27084445 |
| 89 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.26806237 |
| 90 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.25769269 |
| 91 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.24249375 |
| 92 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.23738155 |
| 93 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.23477583 |
| 94 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.22313440 |
| 95 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.21651708 |
| 96 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.21154887 |
| 97 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.17885803 |
| 98 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.17692660 |
| 99 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.15562734 |
| 100 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.15116235 |

