

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | presynaptic membrane assembly (GO:0097105) | 6.83793499 |
| 2 | positive regulation of mitochondrial fission (GO:0090141) | 6.60596014 |
| 3 | negative regulation of gluconeogenesis (GO:0045721) | 5.74959063 |
| 4 | detection of calcium ion (GO:0005513) | 5.56760981 |
| 5 | keratinocyte development (GO:0003334) | 5.33246023 |
| 6 | presynaptic membrane organization (GO:0097090) | 5.30188186 |
| 7 | positive regulation of protein autophosphorylation (GO:0031954) | 5.26956671 |
| 8 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 4.86596422 |
| 9 | positive regulation of neurotransmitter secretion (GO:0001956) | 4.85444096 |
| 10 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 4.67078409 |
| 11 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 4.67078409 |
| 12 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 4.67078409 |
| 13 | L-alpha-amino acid transmembrane transport (GO:1902475) | 4.60306707 |
| 14 | regulation of mitochondrial fission (GO:0090140) | 4.60305575 |
| 15 | positive regulation of glycolytic process (GO:0045821) | 4.59355732 |
| 16 | dendritic spine morphogenesis (GO:0060997) | 4.14262433 |
| 17 | negative regulation of keratinocyte proliferation (GO:0010839) | 4.07163376 |
| 18 | fibroblast migration (GO:0010761) | 4.04335138 |
| 19 | negative regulation of chemokine production (GO:0032682) | 4.00302338 |
| 20 | positive regulation of neurotransmitter transport (GO:0051590) | 3.92584305 |
| 21 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 3.91873186 |
| 22 | toxin transport (GO:1901998) | 3.88077876 |
| 23 | respiratory chain complex IV assembly (GO:0008535) | 3.79841666 |
| 24 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.77228363 |
| 25 | regulation of energy homeostasis (GO:2000505) | 3.66641137 |
| 26 | sphingomyelin metabolic process (GO:0006684) | 3.65835888 |
| 27 | positive regulation of action potential (GO:0045760) | 3.61333459 |
| 28 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.58702438 |
| 29 | positive regulation of insulin secretion (GO:0032024) | 3.56011682 |
| 30 | cytochrome complex assembly (GO:0017004) | 3.52625675 |
| 31 | maternal behavior (GO:0042711) | 3.49612168 |
| 32 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 3.49117015 |
| 33 | cellular response to exogenous dsRNA (GO:0071360) | 3.45737103 |
| 34 | regulation of B cell apoptotic process (GO:0002902) | 3.41658697 |
| 35 | lactate metabolic process (GO:0006089) | 3.41508427 |
| 36 | positive regulation of peptide hormone secretion (GO:0090277) | 3.41044808 |
| 37 | inositol phosphate catabolic process (GO:0071545) | 3.37577234 |
| 38 | spindle assembly involved in mitosis (GO:0090307) | 3.35915780 |
| 39 | negative regulation of execution phase of apoptosis (GO:1900118) | 3.35844810 |
| 40 | negative regulation of organ growth (GO:0046621) | 3.35171513 |
| 41 | snRNA transcription (GO:0009301) | 3.33853970 |
| 42 | positive regulation of peptide secretion (GO:0002793) | 3.31064120 |
| 43 | protein K6-linked ubiquitination (GO:0085020) | 3.30897401 |
| 44 | regulation of metalloenzyme activity (GO:0048552) | 3.28900900 |
| 45 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 3.27509243 |
| 46 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 3.26976599 |
| 47 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.26901233 |
| 48 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.25181643 |
| 49 | neuron cell-cell adhesion (GO:0007158) | 3.20387014 |
| 50 | parental behavior (GO:0060746) | 3.19523457 |
| 51 | regulation of action potential (GO:0098900) | 3.19158496 |
| 52 | multicellular organismal reproductive behavior (GO:0033057) | 3.15379168 |
| 53 | postsynaptic membrane organization (GO:0001941) | 3.14844163 |
| 54 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.13265590 |
| 55 | positive regulation of gluconeogenesis (GO:0045722) | 3.06289437 |
| 56 | nucleobase catabolic process (GO:0046113) | 3.05061481 |
| 57 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.04353847 |
| 58 | mitochondrial fission (GO:0000266) | 3.03970219 |
| 59 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 3.02921134 |
| 60 | membrane assembly (GO:0071709) | 3.01247591 |
| 61 | negative regulation of adherens junction organization (GO:1903392) | 2.95309214 |
| 62 | negative regulation of focal adhesion assembly (GO:0051895) | 2.95309214 |
| 63 | negative regulation of cell junction assembly (GO:1901889) | 2.95309214 |
| 64 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.93937718 |
| 65 | inositol phosphate dephosphorylation (GO:0046855) | 2.93937718 |
| 66 | early endosome to late endosome transport (GO:0045022) | 2.91631823 |
| 67 | positive regulation of Rap GTPase activity (GO:0032854) | 2.91412127 |
| 68 | protein heterotetramerization (GO:0051290) | 2.89743278 |
| 69 | regulation of gluconeogenesis (GO:0006111) | 2.89700918 |
| 70 | negative regulation of membrane potential (GO:0045837) | 2.88386482 |
| 71 | auditory receptor cell differentiation (GO:0042491) | 2.86209648 |
| 72 | myelin maintenance (GO:0043217) | 2.85432677 |
| 73 | platelet dense granule organization (GO:0060155) | 2.83997343 |
| 74 | vesicle docking involved in exocytosis (GO:0006904) | 2.81371717 |
| 75 | regulation of protein sumoylation (GO:0033233) | 2.80881551 |
| 76 | insulin secretion (GO:0030073) | 2.80399438 |
| 77 | regulation of protein autophosphorylation (GO:0031952) | 2.78957537 |
| 78 | adenosine metabolic process (GO:0046085) | 2.78777009 |
| 79 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.78269910 |
| 80 | negative regulation of acute inflammatory response (GO:0002674) | 2.75116665 |
| 81 | peptide catabolic process (GO:0043171) | 2.75113459 |
| 82 | rhodopsin mediated signaling pathway (GO:0016056) | 2.73426214 |
| 83 | cell adhesion mediated by integrin (GO:0033627) | 2.70802189 |
| 84 | mature B cell differentiation (GO:0002335) | 2.69896624 |
| 85 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 2.68871968 |
| 86 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.66464373 |
| 87 | regulation of oxidative phosphorylation (GO:0002082) | 2.66350170 |
| 88 | glomerular basement membrane development (GO:0032836) | 2.65934549 |
| 89 | histamine secretion (GO:0001821) | 2.65113123 |
| 90 | positive regulation of hormone secretion (GO:0046887) | 2.64692108 |
| 91 | protein targeting to vacuole (GO:0006623) | 2.63572188 |
| 92 | protein targeting to lysosome (GO:0006622) | 2.63572188 |
| 93 | establishment of protein localization to vacuole (GO:0072666) | 2.63572188 |
| 94 | vesicle localization (GO:0051648) | 2.60525386 |
| 95 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.59317526 |
| 96 | negative regulation of catecholamine secretion (GO:0033604) | 2.56216603 |
| 97 | neuron maturation (GO:0042551) | 2.56019524 |
| 98 | axoneme assembly (GO:0035082) | 2.54656882 |
| 99 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.54181933 |
| 100 | endocrine pancreas development (GO:0031018) | 2.52455857 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 5.68948066 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.90644451 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.63187657 |
| 4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.42089843 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.20040286 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 11.1533138 |
| 7 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.98897563 |
| 8 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.98545086 |
| 9 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.83489382 |
| 10 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.83267736 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.82576650 |
| 12 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.78592708 |
| 13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.77628594 |
| 14 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.77337628 |
| 15 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.70127207 |
| 16 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.67256344 |
| 17 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.61083094 |
| 18 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.59291919 |
| 19 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.58726623 |
| 20 | AR_25329375_ChIP-Seq_VCAP_Human | 1.51812098 |
| 21 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.51594874 |
| 22 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.50179644 |
| 23 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.48194052 |
| 24 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.47461820 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.46964972 |
| 26 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.45375201 |
| 27 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.44316639 |
| 28 | CJUN_26792858_Chip-Seq_BT549_Human | 1.40910205 |
| 29 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.38166279 |
| 30 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.36736625 |
| 31 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.36284437 |
| 32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33763782 |
| 33 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.32253816 |
| 34 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.27189116 |
| 35 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25760411 |
| 36 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25760411 |
| 37 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.25645510 |
| 38 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.24309894 |
| 39 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.21264371 |
| 40 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.21106369 |
| 41 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.20336752 |
| 42 | TBL1_22424771_ChIP-Seq_293T_Human | 1.20187448 |
| 43 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.20173224 |
| 44 | TP53_16413492_ChIP-PET_HCT116_Human | 1.18556215 |
| 45 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.18359749 |
| 46 | P300_19829295_ChIP-Seq_ESCs_Human | 1.18308228 |
| 47 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.17413781 |
| 48 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.17123853 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.14821899 |
| 50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.14619379 |
| 51 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.14619379 |
| 52 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.14075719 |
| 53 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.13743174 |
| 54 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.12495610 |
| 55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.12110092 |
| 56 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.11601973 |
| 57 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.10826018 |
| 58 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.10826018 |
| 59 | NFYA_21822215_ChIP-Seq_K562_Human | 1.10718563 |
| 60 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.05503177 |
| 61 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.05158092 |
| 62 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.04952463 |
| 63 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.04258835 |
| 64 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.03821373 |
| 65 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.03513982 |
| 66 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.03101432 |
| 67 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.99989995 |
| 68 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.99860196 |
| 69 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99003225 |
| 70 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.98698188 |
| 71 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.98603966 |
| 72 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.98137056 |
| 73 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97622318 |
| 74 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.97575102 |
| 75 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96896936 |
| 76 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.95938997 |
| 77 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95613407 |
| 78 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.94837850 |
| 79 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.94639144 |
| 80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92737716 |
| 81 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.91139564 |
| 82 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.89844304 |
| 83 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.89651956 |
| 84 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.88808631 |
| 85 | TCF4_23295773_ChIP-Seq_U87_Human | 0.88295977 |
| 86 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.88002960 |
| 87 | EWS_26573619_Chip-Seq_HEK293_Human | 0.88000333 |
| 88 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.87454862 |
| 89 | KDM2B_26808549_Chip-Seq_REH_Human | 0.87289485 |
| 90 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.87216463 |
| 91 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.86934878 |
| 92 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.86444404 |
| 93 | NFYB_21822215_ChIP-Seq_K562_Human | 0.86089478 |
| 94 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.84404257 |
| 95 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.82464576 |
| 96 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.82012374 |
| 97 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.81665666 |
| 98 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.81271350 |
| 99 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.80238845 |
| 100 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.79363469 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010234_abnormal_vibrissa_follicle | 7.07697822 |
| 2 | MP0009780_abnormal_chondrocyte_physiolo | 3.73931112 |
| 3 | MP0005379_endocrine/exocrine_gland_phen | 3.66621075 |
| 4 | MP0010352_gastrointestinal_tract_polyps | 3.47725743 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 3.42259585 |
| 6 | MP0003787_abnormal_imprinting | 3.28862547 |
| 7 | MP0000569_abnormal_digit_pigmentation | 3.24669642 |
| 8 | MP0003172_abnormal_lysosome_physiology | 3.03342867 |
| 9 | MP0002163_abnormal_gland_morphology | 3.01849914 |
| 10 | MP0005174_abnormal_tail_pigmentation | 2.60990642 |
| 11 | MP0000013_abnormal_adipose_tissue | 2.60130921 |
| 12 | MP0000015_abnormal_ear_pigmentation | 2.57176484 |
| 13 | MP0004147_increased_porphyrin_level | 2.51225199 |
| 14 | MP0002877_abnormal_melanocyte_morpholog | 2.42727680 |
| 15 | MP0005084_abnormal_gallbladder_morpholo | 2.40998074 |
| 16 | MP0002928_abnormal_bile_duct | 2.30021742 |
| 17 | MP0008877_abnormal_DNA_methylation | 2.27021462 |
| 18 | MP0003880_abnormal_central_pattern | 2.22985794 |
| 19 | MP0002638_abnormal_pupillary_reflex | 2.07470184 |
| 20 | MP0010678_abnormal_skin_adnexa | 2.05496883 |
| 21 | MP0010386_abnormal_urinary_bladder | 1.94124271 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.91160130 |
| 23 | MP0000003_abnormal_adipose_tissue | 1.85548991 |
| 24 | MP0005646_abnormal_pituitary_gland | 1.77005053 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.65772616 |
| 26 | MP0003075_altered_response_to | 1.63310251 |
| 27 | MP0005409_darkened_coat_color | 1.60437627 |
| 28 | MP0001905_abnormal_dopamine_level | 1.60022870 |
| 29 | MP0002295_abnormal_pulmonary_circulatio | 1.59856238 |
| 30 | MP0005408_hypopigmentation | 1.56533926 |
| 31 | MP0002736_abnormal_nociception_after | 1.49012605 |
| 32 | MP0000371_diluted_coat_color | 1.47154575 |
| 33 | MP0001661_extended_life_span | 1.46110557 |
| 34 | MP0002909_abnormal_adrenal_gland | 1.46015702 |
| 35 | MP0000467_abnormal_esophagus_morphology | 1.38486449 |
| 36 | MP0002876_abnormal_thyroid_physiology | 1.36992273 |
| 37 | MP0006054_spinal_hemorrhage | 1.36127528 |
| 38 | MP0002693_abnormal_pancreas_physiology | 1.33466850 |
| 39 | MP0005083_abnormal_biliary_tract | 1.32269839 |
| 40 | MP0008438_abnormal_cutaneous_collagen | 1.29606007 |
| 41 | MP0003300_gastrointestinal_ulcer | 1.28237952 |
| 42 | MP0001984_abnormal_olfaction | 1.27853722 |
| 43 | MP0004270_analgesia | 1.26849406 |
| 44 | MP0000516_abnormal_urinary_system | 1.21278125 |
| 45 | MP0005367_renal/urinary_system_phenotyp | 1.21278125 |
| 46 | MP0001440_abnormal_grooming_behavior | 1.19755080 |
| 47 | MP0000538_abnormal_urinary_bladder | 1.15587734 |
| 48 | MP0003303_peritoneal_inflammation | 1.15288196 |
| 49 | MP0005464_abnormal_platelet_physiology | 1.14333487 |
| 50 | MP0001348_abnormal_lacrimal_gland | 1.12188309 |
| 51 | MP0002075_abnormal_coat/hair_pigmentati | 1.11600115 |
| 52 | MP0005645_abnormal_hypothalamus_physiol | 1.10282457 |
| 53 | MP0002166_altered_tumor_susceptibility | 1.10080185 |
| 54 | MP0003186_abnormal_redox_activity | 1.09465173 |
| 55 | MP0003122_maternal_imprinting | 1.05161334 |
| 56 | MP0004272_abnormal_basement_membrane | 1.03946588 |
| 57 | MP0003566_abnormal_cell_adhesion | 1.03148833 |
| 58 | MP0003315_abnormal_perineum_morphology | 0.99538371 |
| 59 | MP0002822_catalepsy | 0.98488303 |
| 60 | MP0008057_abnormal_DNA_replication | 0.97886256 |
| 61 | MP0001186_pigmentation_phenotype | 0.95594810 |
| 62 | MP0004215_abnormal_myocardial_fiber | 0.95232676 |
| 63 | MP0009278_abnormal_bone_marrow | 0.94245546 |
| 64 | MP0003252_abnormal_bile_duct | 0.93389935 |
| 65 | MP0006072_abnormal_retinal_apoptosis | 0.91916812 |
| 66 | MP0001944_abnormal_pancreas_morphology | 0.91899526 |
| 67 | MP0001756_abnormal_urination | 0.90829434 |
| 68 | MP0010368_abnormal_lymphatic_system | 0.89508382 |
| 69 | MP0002177_abnormal_outer_ear | 0.88606524 |
| 70 | MP0001501_abnormal_sleep_pattern | 0.87376593 |
| 71 | MP0005187_abnormal_penis_morphology | 0.86382648 |
| 72 | MP0002006_tumorigenesis | 0.86063248 |
| 73 | MP0004264_abnormal_extraembryonic_tissu | 0.86007598 |
| 74 | MP0005397_hematopoietic_system_phenotyp | 0.85971309 |
| 75 | MP0001545_abnormal_hematopoietic_system | 0.85971309 |
| 76 | MP0004859_abnormal_synaptic_plasticity | 0.83016315 |
| 77 | MP0002095_abnormal_skin_pigmentation | 0.81572449 |
| 78 | MP0005394_taste/olfaction_phenotype | 0.78772379 |
| 79 | MP0005499_abnormal_olfactory_system | 0.78772379 |
| 80 | MP0001765_abnormal_ion_homeostasis | 0.78570335 |
| 81 | MP0002332_abnormal_exercise_endurance | 0.78526670 |
| 82 | MP0001968_abnormal_touch/_nociception | 0.78391674 |
| 83 | MP0001542_abnormal_bone_strength | 0.78389170 |
| 84 | MP0002060_abnormal_skin_morphology | 0.78382199 |
| 85 | MP0005647_abnormal_sex_gland | 0.72071862 |
| 86 | MP0004134_abnormal_chest_morphology | 0.70973597 |
| 87 | MP0003183_abnormal_peptide_metabolism | 0.70513765 |
| 88 | MP0005197_abnormal_uvea_morphology | 0.67873841 |
| 89 | MP0005636_abnormal_mineral_homeostasis | 0.67367815 |
| 90 | MP0002896_abnormal_bone_mineralization | 0.66989436 |
| 91 | MP0005319_abnormal_enzyme/_coenzyme | 0.65588231 |
| 92 | MP0005248_abnormal_Harderian_gland | 0.65226043 |
| 93 | MP0000343_altered_response_to | 0.60644498 |
| 94 | MP0002557_abnormal_social/conspecific_i | 0.59069796 |
| 95 | MP0008872_abnormal_physiological_respon | 0.59067727 |
| 96 | MP0005386_behavior/neurological_phenoty | 0.58530000 |
| 97 | MP0004924_abnormal_behavior | 0.58530000 |
| 98 | MP0005220_abnormal_exocrine_pancreas | 0.58028662 |
| 99 | MP0008789_abnormal_olfactory_epithelium | 0.57871020 |
| 100 | MP0003091_abnormal_cell_migration | 0.56471686 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hypoglycemic seizures (HP:0002173) | 7.94658862 |
| 2 | Hyperinsulinemic hypoglycemia (HP:0000825) | 6.27247298 |
| 3 | Symptomatic seizures (HP:0011145) | 6.08243377 |
| 4 | Hematochezia (HP:0002573) | 5.79202131 |
| 5 | Hypoglycemic coma (HP:0001325) | 5.68444754 |
| 6 | Albinism (HP:0001022) | 4.91178199 |
| 7 | Hyperglycemia (HP:0003074) | 4.33572665 |
| 8 | Ketoacidosis (HP:0001993) | 4.11797920 |
| 9 | Enlarged penis (HP:0000040) | 3.98757896 |
| 10 | Late onset (HP:0003584) | 3.94839789 |
| 11 | Hyperthyroidism (HP:0000836) | 3.83878956 |
| 12 | Cutaneous melanoma (HP:0012056) | 3.54632359 |
| 13 | Conjunctival hamartoma (HP:0100780) | 3.48085246 |
| 14 | Asymmetry of the thorax (HP:0001555) | 3.36792870 |
| 15 | Abnormality of endocrine pancreas physiology (HP:0012093) | 3.26010206 |
| 16 | Abnormality of the pancreatic islet cells (HP:0006476) | 3.26010206 |
| 17 | Impaired proprioception (HP:0010831) | 3.08099323 |
| 18 | Hypomagnesemia (HP:0002917) | 3.04406772 |
| 19 | Testicular neoplasm (HP:0010788) | 2.89408855 |
| 20 | Bone cyst (HP:0012062) | 2.88901042 |
| 21 | Hamartoma of the eye (HP:0010568) | 2.81560379 |
| 22 | Neoplasm of the adrenal cortex (HP:0100641) | 2.76007365 |
| 23 | Large for gestational age (HP:0001520) | 2.74290167 |
| 24 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.72919840 |
| 25 | Generalized hypopigmentation (HP:0007513) | 2.64159327 |
| 26 | Hemiparesis (HP:0001269) | 2.62267855 |
| 27 | Follicular hyperkeratosis (HP:0007502) | 2.53337017 |
| 28 | Delayed gross motor development (HP:0002194) | 2.49968597 |
| 29 | Ocular albinism (HP:0001107) | 2.46948199 |
| 30 | Abnormality of magnesium homeostasis (HP:0004921) | 2.45645540 |
| 31 | Lymphangioma (HP:0100764) | 2.41781621 |
| 32 | Prominent metopic ridge (HP:0005487) | 2.40996764 |
| 33 | Buphthalmos (HP:0000557) | 2.38634729 |
| 34 | Hydroxyprolinuria (HP:0003080) | 2.37365254 |
| 35 | Abnormality of proline metabolism (HP:0010907) | 2.37365254 |
| 36 | Iris hypopigmentation (HP:0007730) | 2.33432096 |
| 37 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.32166479 |
| 38 | Hyperventilation (HP:0002883) | 2.31482026 |
| 39 | Metaphyseal dysplasia (HP:0100255) | 2.31241735 |
| 40 | Urethral obstruction (HP:0000796) | 2.29099303 |
| 41 | Abnormality of the metopic suture (HP:0005556) | 2.28514326 |
| 42 | Prolonged bleeding time (HP:0003010) | 2.25518133 |
| 43 | Medial flaring of the eyebrow (HP:0010747) | 2.24008222 |
| 44 | Ketosis (HP:0001946) | 2.21765889 |
| 45 | Tetraparesis (HP:0002273) | 2.21397407 |
| 46 | Congenital glaucoma (HP:0001087) | 2.20500060 |
| 47 | Poor suck (HP:0002033) | 2.18031755 |
| 48 | Insulin resistance (HP:0000855) | 2.15947196 |
| 49 | Genu recurvatum (HP:0002816) | 2.12440328 |
| 50 | Hypokinesia (HP:0002375) | 2.10748225 |
| 51 | Polyphagia (HP:0002591) | 2.08605128 |
| 52 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.06652854 |
| 53 | Amblyopia (HP:0000646) | 2.04512481 |
| 54 | Increased serum pyruvate (HP:0003542) | 2.02980004 |
| 55 | Atonic seizures (HP:0010819) | 1.97426054 |
| 56 | Venous insufficiency (HP:0005293) | 1.96517511 |
| 57 | Poor head control (HP:0002421) | 1.95309602 |
| 58 | Nephrogenic diabetes insipidus (HP:0009806) | 1.94192834 |
| 59 | Hyperphosphatemia (HP:0002905) | 1.94192110 |
| 60 | Increased variability in muscle fiber diameter (HP:0003557) | 1.93984423 |
| 61 | Neoplasm of the adrenal gland (HP:0100631) | 1.92112000 |
| 62 | Hypoalbuminemia (HP:0003073) | 1.91634660 |
| 63 | Abnormal albumin level (HP:0012116) | 1.91634660 |
| 64 | Heterochromia iridis (HP:0001100) | 1.90011880 |
| 65 | Neonatal respiratory distress (HP:0002643) | 1.89562953 |
| 66 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.87777810 |
| 67 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.87777810 |
| 68 | Abnormality of glycolipid metabolism (HP:0010969) | 1.87777810 |
| 69 | Soft skin (HP:0000977) | 1.87419580 |
| 70 | Palpebral edema (HP:0100540) | 1.86954019 |
| 71 | Purpura (HP:0000979) | 1.85162032 |
| 72 | Hypoproteinemia (HP:0003075) | 1.84123042 |
| 73 | Muscular hypotonia of the trunk (HP:0008936) | 1.82782820 |
| 74 | Vertebral compression fractures (HP:0002953) | 1.81915137 |
| 75 | Patchy hypopigmentation of hair (HP:0011365) | 1.80790219 |
| 76 | Gingival overgrowth (HP:0000212) | 1.80036517 |
| 77 | Aortic regurgitation (HP:0001659) | 1.79555612 |
| 78 | Dyschromatopsia (HP:0007641) | 1.78267412 |
| 79 | Mucopolysacchariduria (HP:0008155) | 1.77877903 |
| 80 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.77877903 |
| 81 | Abnormality of lateral ventricle (HP:0030047) | 1.77499854 |
| 82 | Petechiae (HP:0000967) | 1.76657694 |
| 83 | Bruising susceptibility (HP:0000978) | 1.73140999 |
| 84 | Protruding tongue (HP:0010808) | 1.72838167 |
| 85 | Premature rupture of membranes (HP:0001788) | 1.72116327 |
| 86 | Mitral stenosis (HP:0001718) | 1.72015214 |
| 87 | Pancreatic fibrosis (HP:0100732) | 1.70613578 |
| 88 | Angiofibromas (HP:0010615) | 1.70307827 |
| 89 | Adenoma sebaceum (HP:0009720) | 1.70307827 |
| 90 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.69983063 |
| 91 | Menstrual irregularities (HP:0000858) | 1.68246717 |
| 92 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.67822313 |
| 93 | Furrowed tongue (HP:0000221) | 1.67752396 |
| 94 | Mesangial abnormality (HP:0001966) | 1.67495784 |
| 95 | Hypopigmentation of the fundus (HP:0007894) | 1.65813386 |
| 96 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.65734170 |
| 97 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.65734170 |
| 98 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.65734170 |
| 99 | Hypoplasia of the fovea (HP:0007750) | 1.64980862 |
| 100 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.64980862 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 8.12590809 |
| 2 | MST4 | 6.35152247 |
| 3 | TNIK | 4.30307775 |
| 4 | FGFR2 | 3.88112218 |
| 5 | NUAK1 | 3.02163941 |
| 6 | NTRK3 | 2.79344563 |
| 7 | NLK | 2.60319708 |
| 8 | ACVR1B | 2.49129910 |
| 9 | DMPK | 2.30072464 |
| 10 | CASK | 2.10677450 |
| 11 | STK3 | 1.92719233 |
| 12 | ROCK2 | 1.81570758 |
| 13 | BMPR1B | 1.50908798 |
| 14 | FGFR3 | 1.50379224 |
| 15 | MAP3K14 | 1.41722573 |
| 16 | PHKG1 | 1.41164176 |
| 17 | PHKG2 | 1.41164176 |
| 18 | MYLK | 1.36338282 |
| 19 | ILK | 1.29461129 |
| 20 | PNCK | 1.26267903 |
| 21 | ROCK1 | 1.22043811 |
| 22 | STK10 | 1.21712457 |
| 23 | NEK9 | 1.18544876 |
| 24 | DAPK2 | 1.17467377 |
| 25 | ADRBK2 | 1.16851436 |
| 26 | PRKCE | 1.11572583 |
| 27 | STK4 | 1.07357944 |
| 28 | EPHB2 | 1.07027249 |
| 29 | AKT2 | 1.01398691 |
| 30 | PLK2 | 0.99727859 |
| 31 | FER | 0.93831621 |
| 32 | PRKG2 | 0.93411457 |
| 33 | STK16 | 0.92297094 |
| 34 | SGK2 | 0.86775906 |
| 35 | INSRR | 0.83989768 |
| 36 | RAF1 | 0.83473908 |
| 37 | MAP3K10 | 0.82172596 |
| 38 | LRRK2 | 0.81220988 |
| 39 | CAMKK2 | 0.80706957 |
| 40 | ICK | 0.79864693 |
| 41 | MAPK11 | 0.79578358 |
| 42 | ADRBK1 | 0.79073474 |
| 43 | TGFBR1 | 0.76904033 |
| 44 | YES1 | 0.74766774 |
| 45 | BCKDK | 0.74607314 |
| 46 | SGK494 | 0.69120344 |
| 47 | SGK223 | 0.69120344 |
| 48 | MAP4K2 | 0.66698610 |
| 49 | CDK3 | 0.63893224 |
| 50 | HIPK2 | 0.62228707 |
| 51 | GSK3A | 0.60427386 |
| 52 | DDR2 | 0.59316470 |
| 53 | GRK1 | 0.55341051 |
| 54 | TRPM7 | 0.55150348 |
| 55 | PRKCI | 0.54037806 |
| 56 | MAP3K4 | 0.53958994 |
| 57 | PDGFRA | 0.53794347 |
| 58 | STK11 | 0.53532211 |
| 59 | PTK2 | 0.51425753 |
| 60 | KIT | 0.51364584 |
| 61 | PRKCQ | 0.49006682 |
| 62 | PRKG1 | 0.47629256 |
| 63 | PTK2B | 0.46473003 |
| 64 | MAP3K2 | 0.45811342 |
| 65 | TIE1 | 0.45312431 |
| 66 | CDK5 | 0.44389830 |
| 67 | IKBKB | 0.44293680 |
| 68 | SGK3 | 0.41962666 |
| 69 | RPS6KA4 | 0.41714885 |
| 70 | PAK2 | 0.41028706 |
| 71 | MAPK7 | 0.39062170 |
| 72 | STK38L | 0.38585282 |
| 73 | RPS6KA2 | 0.37335683 |
| 74 | MAP3K8 | 0.36356071 |
| 75 | TEC | 0.35075721 |
| 76 | PAK3 | 0.34920332 |
| 77 | PINK1 | 0.34157895 |
| 78 | LYN | 0.33917471 |
| 79 | CAMK2A | 0.33890778 |
| 80 | MAP2K6 | 0.33819889 |
| 81 | TBK1 | 0.32470261 |
| 82 | MAP2K7 | 0.31987559 |
| 83 | DAPK3 | 0.31000041 |
| 84 | CAMK1G | 0.27821166 |
| 85 | PRKACA | 0.27173456 |
| 86 | PLK3 | 0.24854810 |
| 87 | RIPK4 | 0.23526867 |
| 88 | CSNK1G1 | 0.20940262 |
| 89 | PAK1 | 0.19601117 |
| 90 | CAMK1 | 0.18982862 |
| 91 | AKT3 | 0.18555269 |
| 92 | DAPK1 | 0.17012207 |
| 93 | CDK6 | 0.15290568 |
| 94 | PIK3CG | 0.14145112 |
| 95 | RPS6KL1 | 0.13101422 |
| 96 | RPS6KC1 | 0.13101422 |
| 97 | PRKACB | 0.12822640 |
| 98 | JAK1 | 0.12456932 |
| 99 | BMPR2 | 0.12255554 |
| 100 | PRKACG | 0.11813624 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 4.73180781 |
| 2 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 4.53324329 |
| 3 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 4.50288432 |
| 4 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 3.75375521 |
| 5 | Insulin secretion_Homo sapiens_hsa04911 | 3.17556845 |
| 6 | Folate biosynthesis_Homo sapiens_hsa00790 | 2.37009742 |
| 7 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.30092527 |
| 8 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.17314347 |
| 9 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.15972371 |
| 10 | Cocaine addiction_Homo sapiens_hsa05030 | 2.12706407 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.05429838 |
| 12 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.83953320 |
| 13 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.82912891 |
| 14 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.65268181 |
| 15 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.58710938 |
| 16 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.51937930 |
| 17 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.44781160 |
| 18 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.41795430 |
| 19 | Renin secretion_Homo sapiens_hsa04924 | 1.41579236 |
| 20 | Other glycan degradation_Homo sapiens_hsa00511 | 1.37005351 |
| 21 | Circadian rhythm_Homo sapiens_hsa04710 | 1.30413737 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.18431149 |
| 23 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.18047062 |
| 24 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.16737750 |
| 25 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.16642886 |
| 26 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.15988552 |
| 27 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.10917595 |
| 28 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.07332872 |
| 29 | Protein export_Homo sapiens_hsa03060 | 1.04213972 |
| 30 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.99517009 |
| 31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.99140296 |
| 32 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.99032781 |
| 33 | Focal adhesion_Homo sapiens_hsa04510 | 0.97209103 |
| 34 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.96348832 |
| 35 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.93845084 |
| 36 | Circadian entrainment_Homo sapiens_hsa04713 | 0.91663467 |
| 37 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.91527332 |
| 38 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.91190930 |
| 39 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.90238838 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 0.90220965 |
| 41 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.87293539 |
| 42 | Mineral absorption_Homo sapiens_hsa04978 | 0.84519222 |
| 43 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.82171602 |
| 44 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.81906275 |
| 45 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.80346452 |
| 46 | ABC transporters_Homo sapiens_hsa02010 | 0.79011657 |
| 47 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74595170 |
| 48 | Prostate cancer_Homo sapiens_hsa05215 | 0.71056393 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.67781938 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.65250566 |
| 51 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.65145177 |
| 52 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.63941554 |
| 53 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.61989779 |
| 54 | Long-term depression_Homo sapiens_hsa04730 | 0.60261866 |
| 55 | Lysosome_Homo sapiens_hsa04142 | 0.59559732 |
| 56 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.57819840 |
| 57 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.57804674 |
| 58 | Amoebiasis_Homo sapiens_hsa05146 | 0.56608476 |
| 59 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.56325878 |
| 60 | Histidine metabolism_Homo sapiens_hsa00340 | 0.54858598 |
| 61 | Salivary secretion_Homo sapiens_hsa04970 | 0.54674052 |
| 62 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.54664638 |
| 63 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.52887092 |
| 64 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.52309456 |
| 65 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.51924192 |
| 66 | Insulin resistance_Homo sapiens_hsa04931 | 0.51637560 |
| 67 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.51192757 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51133580 |
| 69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51028216 |
| 70 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.48053176 |
| 71 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.47867779 |
| 72 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.47588280 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44532175 |
| 74 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.43023773 |
| 75 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.41932306 |
| 76 | Pertussis_Homo sapiens_hsa05133 | 0.41517589 |
| 77 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.40166431 |
| 78 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.38645565 |
| 79 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.36645297 |
| 80 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.35103678 |
| 81 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.33873802 |
| 82 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33377205 |
| 83 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.31024173 |
| 84 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.30608437 |
| 85 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.30074959 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.29886025 |
| 87 | GABAergic synapse_Homo sapiens_hsa04727 | 0.29193830 |
| 88 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.28159135 |
| 89 | Shigellosis_Homo sapiens_hsa05131 | 0.27669678 |
| 90 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.26579829 |
| 91 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.25312789 |
| 92 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.24783046 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.24329533 |
| 94 | Phagosome_Homo sapiens_hsa04145 | 0.22808254 |
| 95 | Tight junction_Homo sapiens_hsa04530 | 0.21824823 |
| 96 | Endocytosis_Homo sapiens_hsa04144 | 0.21689487 |
| 97 | Bile secretion_Homo sapiens_hsa04976 | 0.21156070 |
| 98 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.20176176 |
| 99 | Morphine addiction_Homo sapiens_hsa05032 | 0.20029322 |
| 100 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.19867372 |

