

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | translational termination (GO:0006415) | 9.75146651 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 8.72483541 |
| 3 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 8.23057944 |
| 4 | translational elongation (GO:0006414) | 8.12038888 |
| 5 | cotranslational protein targeting to membrane (GO:0006613) | 8.09533245 |
| 6 | protein targeting to ER (GO:0045047) | 8.07093251 |
| 7 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 7.71527914 |
| 8 | protein localization to endoplasmic reticulum (GO:0070972) | 7.58084064 |
| 9 | viral life cycle (GO:0019058) | 7.43454883 |
| 10 | cellular protein complex disassembly (GO:0043624) | 7.43266481 |
| 11 | maturation of SSU-rRNA (GO:0030490) | 7.40459810 |
| 12 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 7.17115169 |
| 13 | protein complex disassembly (GO:0043241) | 6.29167551 |
| 14 | translational initiation (GO:0006413) | 6.18521331 |
| 15 | macromolecular complex disassembly (GO:0032984) | 5.87786169 |
| 16 | ribosomal large subunit biogenesis (GO:0042273) | 5.86484650 |
| 17 | ribonucleoprotein complex biogenesis (GO:0022613) | 5.55306363 |
| 18 | protein targeting to membrane (GO:0006612) | 5.47970987 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 5.10119758 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.10119758 |
| 21 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 5.05398471 |
| 22 | cellular component biogenesis (GO:0044085) | 4.87869945 |
| 23 | mRNA catabolic process (GO:0006402) | 4.76889099 |
| 24 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.74971415 |
| 25 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.74971415 |
| 26 | translation (GO:0006412) | 4.73319631 |
| 27 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.70630781 |
| 28 | chaperone-mediated protein transport (GO:0072321) | 4.42051106 |
| 29 | behavioral response to nicotine (GO:0035095) | 4.28267082 |
| 30 | RNA catabolic process (GO:0006401) | 4.28147075 |
| 31 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.27124547 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.02646405 |
| 33 | protein complex biogenesis (GO:0070271) | 4.01148883 |
| 34 | cardiovascular system development (GO:0072358) | 3.94966705 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.75366041 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.75366041 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.75366041 |
| 38 | valine metabolic process (GO:0006573) | 3.75339107 |
| 39 | protein neddylation (GO:0045116) | 3.72965502 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.72103350 |
| 41 | regulation of cellular respiration (GO:0043457) | 3.70702417 |
| 42 | establishment of protein localization to membrane (GO:0090150) | 3.70326391 |
| 43 | respiratory chain complex IV assembly (GO:0008535) | 3.70227915 |
| 44 | electron transport chain (GO:0022900) | 3.67102288 |
| 45 | cytochrome complex assembly (GO:0017004) | 3.65948337 |
| 46 | mitochondrion transport along microtubule (GO:0047497) | 3.63664384 |
| 47 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.63664384 |
| 48 | ribosome biogenesis (GO:0042254) | 3.61776992 |
| 49 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.54618990 |
| 50 | protein targeting (GO:0006605) | 3.52070699 |
| 51 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.50409185 |
| 52 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 3.47351706 |
| 53 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.39313652 |
| 54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.39313652 |
| 55 | cell proliferation in forebrain (GO:0021846) | 3.36868535 |
| 56 | establishment of mitochondrion localization (GO:0051654) | 3.32965938 |
| 57 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.30676943 |
| 58 | establishment of protein localization to organelle (GO:0072594) | 3.29385473 |
| 59 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.28468712 |
| 60 | GTP biosynthetic process (GO:0006183) | 3.25133280 |
| 61 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.24788828 |
| 62 | ATP biosynthetic process (GO:0006754) | 3.24680053 |
| 63 | ubiquinone biosynthetic process (GO:0006744) | 3.23904147 |
| 64 | sequestering of actin monomers (GO:0042989) | 3.21518309 |
| 65 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.16898925 |
| 66 | negative regulation of muscle hypertrophy (GO:0014741) | 3.13321566 |
| 67 | maturation of 5.8S rRNA (GO:0000460) | 3.11237159 |
| 68 | ovulation cycle (GO:0042698) | 3.09649302 |
| 69 | rRNA processing (GO:0006364) | 3.07188199 |
| 70 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.06871959 |
| 71 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.05808348 |
| 72 | rRNA metabolic process (GO:0016072) | 3.03161760 |
| 73 | protein localization to membrane (GO:0072657) | 3.02077435 |
| 74 | DNA deamination (GO:0045006) | 2.94221479 |
| 75 | ubiquinone metabolic process (GO:0006743) | 2.92204214 |
| 76 | somite development (GO:0061053) | 2.82174278 |
| 77 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.81106322 |
| 78 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.80409078 |
| 79 | N-terminal protein amino acid acetylation (GO:0006474) | 2.78873838 |
| 80 | UTP biosynthetic process (GO:0006228) | 2.78234791 |
| 81 | nonmotile primary cilium assembly (GO:0035058) | 2.77369999 |
| 82 | regulation of oxidative stress-induced neuron death (GO:1903203) | 2.75587755 |
| 83 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.74381067 |
| 84 | signal peptide processing (GO:0006465) | 2.69284903 |
| 85 | positive regulation of respiratory burst (GO:0060267) | 2.68987208 |
| 86 | retinal ganglion cell axon guidance (GO:0031290) | 2.66384721 |
| 87 | negative regulation of appetite (GO:0032099) | 2.65084414 |
| 88 | negative regulation of response to food (GO:0032096) | 2.65084414 |
| 89 | negative regulation of glycogen biosynthetic process (GO:0045719) | 2.63695813 |
| 90 | quinone biosynthetic process (GO:1901663) | 2.60010846 |
| 91 | cellular response to interferon-beta (GO:0035458) | 2.58990655 |
| 92 | establishment of protein localization to mitochondrion (GO:0072655) | 2.56837792 |
| 93 | positive regulation of T cell apoptotic process (GO:0070234) | 2.55819826 |
| 94 | UTP metabolic process (GO:0046051) | 2.47354763 |
| 95 | seminiferous tubule development (GO:0072520) | 2.46392678 |
| 96 | resolution of meiotic recombination intermediates (GO:0000712) | 2.46340761 |
| 97 | negative regulation of potassium ion transport (GO:0043267) | 2.45851102 |
| 98 | hydrogen ion transmembrane transport (GO:1902600) | 2.43590848 |
| 99 | ribosomal small subunit biogenesis (GO:0042274) | 10.8927822 |
| 100 | viral transcription (GO:0019083) | 10.2112201 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.58349944 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.77181182 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.67649620 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.65661747 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.42989682 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.02106985 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.82898672 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.74462807 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.70689288 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.47861617 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.38805082 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.32864870 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.18748456 |
| 14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.16078255 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.06993701 |
| 16 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.98032152 |
| 17 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.89061717 |
| 18 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.88930004 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.88172814 |
| 20 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.87937465 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.85810957 |
| 22 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.83576075 |
| 23 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.82324659 |
| 24 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.81761952 |
| 25 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.74345420 |
| 26 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.72610613 |
| 27 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.68050787 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.65847565 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.62292995 |
| 30 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.60737565 |
| 31 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.58825182 |
| 32 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.55264228 |
| 33 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.54006465 |
| 34 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.52869681 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.52165653 |
| 36 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.49978811 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47911871 |
| 38 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.47756131 |
| 39 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.46383484 |
| 40 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.44332259 |
| 41 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.43593965 |
| 42 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.42079142 |
| 43 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.39443949 |
| 44 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.36630605 |
| 45 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.35863678 |
| 46 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.34712361 |
| 47 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32722709 |
| 48 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.31731331 |
| 49 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.30210041 |
| 50 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.30098287 |
| 51 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.27675566 |
| 52 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.27317550 |
| 53 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.26602777 |
| 54 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.24912696 |
| 55 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.24499791 |
| 56 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.23988179 |
| 57 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.22205844 |
| 58 | SA1_27219007_Chip-Seq_Bcells_Human | 1.20040528 |
| 59 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.18215764 |
| 60 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.18215764 |
| 61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.16976786 |
| 62 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.16329615 |
| 63 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13247933 |
| 64 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.12922051 |
| 65 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.12026341 |
| 66 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.10599488 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.10487876 |
| 68 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.09331338 |
| 69 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.09007681 |
| 70 | NCOR_22424771_ChIP-Seq_293T_Human | 1.08509776 |
| 71 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.07475566 |
| 72 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.07358519 |
| 73 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.05806834 |
| 74 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.05139245 |
| 75 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03060748 |
| 76 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.02545023 |
| 77 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.02039323 |
| 78 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.01000913 |
| 79 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00775082 |
| 80 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.00667246 |
| 81 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00348449 |
| 82 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.00151582 |
| 83 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.98388264 |
| 84 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.97949378 |
| 85 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.95757168 |
| 86 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.95247259 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.94753004 |
| 88 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.94410433 |
| 89 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.93024603 |
| 90 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.92895964 |
| 91 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.92830361 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.92802797 |
| 93 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.92136837 |
| 94 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.91430293 |
| 95 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.90057738 |
| 96 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.88412724 |
| 97 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88251718 |
| 98 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86181752 |
| 99 | FUS_26573619_Chip-Seq_HEK293_Human | 0.85794738 |
| 100 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.84947375 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 8.69702171 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.07909221 |
| 3 | MP0002653_abnormal_ependyma_morphology | 3.28854971 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 3.04072827 |
| 5 | MP0003123_paternal_imprinting | 3.02995201 |
| 6 | MP0003787_abnormal_imprinting | 2.88185604 |
| 7 | MP0002163_abnormal_gland_morphology | 2.61499070 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.43147387 |
| 9 | MP0001986_abnormal_taste_sensitivity | 2.30531700 |
| 10 | MP0003646_muscle_fatigue | 2.29687372 |
| 11 | MP0008789_abnormal_olfactory_epithelium | 2.26193585 |
| 12 | MP0004145_abnormal_muscle_electrophysio | 2.25051687 |
| 13 | MP0005646_abnormal_pituitary_gland | 2.12832038 |
| 14 | MP0003122_maternal_imprinting | 2.08367259 |
| 15 | MP0003315_abnormal_perineum_morphology | 1.93309791 |
| 16 | MP0006054_spinal_hemorrhage | 1.89215743 |
| 17 | MP0005499_abnormal_olfactory_system | 1.86844721 |
| 18 | MP0005394_taste/olfaction_phenotype | 1.86844721 |
| 19 | MP0001188_hyperpigmentation | 1.72009180 |
| 20 | MP0003121_genomic_imprinting | 1.67635014 |
| 21 | MP0002638_abnormal_pupillary_reflex | 1.65183501 |
| 22 | MP0002160_abnormal_reproductive_system | 1.64721926 |
| 23 | MP0003186_abnormal_redox_activity | 1.57256958 |
| 24 | MP0005423_abnormal_somatic_nervous | 1.56495565 |
| 25 | MP0005379_endocrine/exocrine_gland_phen | 1.52429597 |
| 26 | MP0001529_abnormal_vocalization | 1.49605128 |
| 27 | MP0005389_reproductive_system_phenotype | 1.45797003 |
| 28 | MP0003011_delayed_dark_adaptation | 1.43122823 |
| 29 | MP0004142_abnormal_muscle_tone | 1.39325184 |
| 30 | MP0004084_abnormal_cardiac_muscle | 1.37807395 |
| 31 | MP0004130_abnormal_muscle_cell | 1.33214159 |
| 32 | MP0001919_abnormal_reproductive_system | 1.32675550 |
| 33 | MP0001348_abnormal_lacrimal_gland | 1.31836063 |
| 34 | MP0000049_abnormal_middle_ear | 1.31041764 |
| 35 | MP0006276_abnormal_autonomic_nervous | 1.30854516 |
| 36 | MP0002272_abnormal_nervous_system | 1.27309187 |
| 37 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25490403 |
| 38 | MP0005187_abnormal_penis_morphology | 1.22369539 |
| 39 | MP0001293_anophthalmia | 1.18397178 |
| 40 | MP0003136_yellow_coat_color | 1.14815641 |
| 41 | MP0003693_abnormal_embryo_hatching | 1.14809005 |
| 42 | MP0001968_abnormal_touch/_nociception | 1.12593021 |
| 43 | MP0005551_abnormal_eye_electrophysiolog | 1.12314296 |
| 44 | MP0006072_abnormal_retinal_apoptosis | 1.10212160 |
| 45 | MP0008872_abnormal_physiological_respon | 1.08719220 |
| 46 | MP0003880_abnormal_central_pattern | 1.08682557 |
| 47 | MP0002938_white_spotting | 1.06640756 |
| 48 | MP0002234_abnormal_pharynx_morphology | 1.04328993 |
| 49 | MP0000631_abnormal_neuroendocrine_gland | 1.03009438 |
| 50 | MP0002736_abnormal_nociception_after | 1.02199744 |
| 51 | MP0009250_abnormal_appendicular_skeleto | 1.00560992 |
| 52 | MP0009046_muscle_twitch | 0.98045928 |
| 53 | MP0000613_abnormal_salivary_gland | 0.97112719 |
| 54 | MP0005377_hearing/vestibular/ear_phenot | 0.96087355 |
| 55 | MP0003878_abnormal_ear_physiology | 0.96087355 |
| 56 | MP0000678_abnormal_parathyroid_gland | 0.95881819 |
| 57 | MP0009745_abnormal_behavioral_response | 0.94823628 |
| 58 | MP0003195_calcinosis | 0.93946077 |
| 59 | MP0005623_abnormal_meninges_morphology | 0.93030410 |
| 60 | MP0001286_abnormal_eye_development | 0.92042857 |
| 61 | MP0002557_abnormal_social/conspecific_i | 0.90355607 |
| 62 | MP0000955_abnormal_spinal_cord | 0.89901381 |
| 63 | MP0002095_abnormal_skin_pigmentation | 0.88470851 |
| 64 | MP0000778_abnormal_nervous_system | 0.87443581 |
| 65 | MP0003942_abnormal_urinary_system | 0.84519038 |
| 66 | MP0002184_abnormal_innervation | 0.84306081 |
| 67 | MP0002822_catalepsy | 0.83538974 |
| 68 | MP0008775_abnormal_heart_ventricle | 0.81476318 |
| 69 | MP0001663_abnormal_digestive_system | 0.80798324 |
| 70 | MP0005195_abnormal_posterior_eye | 0.80545182 |
| 71 | MP0009053_abnormal_anal_canal | 0.79735827 |
| 72 | MP0002752_abnormal_somatic_nervous | 0.78787657 |
| 73 | MP0005084_abnormal_gallbladder_morpholo | 0.78287090 |
| 74 | MP0001905_abnormal_dopamine_level | 0.77890392 |
| 75 | MP0002249_abnormal_larynx_morphology | 0.77750180 |
| 76 | MP0004742_abnormal_vestibular_system | 0.77298062 |
| 77 | MP0001970_abnormal_pain_threshold | 0.76951933 |
| 78 | MP0001440_abnormal_grooming_behavior | 0.76167824 |
| 79 | MP0004858_abnormal_nervous_system | 0.75414871 |
| 80 | MP0004885_abnormal_endolymph | 0.70982944 |
| 81 | MP0002233_abnormal_nose_morphology | 0.70118199 |
| 82 | MP0003119_abnormal_digestive_system | 0.69601643 |
| 83 | MP0002572_abnormal_emotion/affect_behav | 0.69175868 |
| 84 | MP0005220_abnormal_exocrine_pancreas | 0.68972760 |
| 85 | MP0001485_abnormal_pinna_reflex | 0.68304861 |
| 86 | MP0002733_abnormal_thermal_nociception | 0.68269997 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 0.66653665 |
| 88 | MP0002697_abnormal_eye_size | 0.66390151 |
| 89 | MP0000372_irregular_coat_pigmentation | 0.65638046 |
| 90 | MP0001984_abnormal_olfaction | 0.65441152 |
| 91 | MP0002210_abnormal_sex_determination | 0.64614363 |
| 92 | MP0002102_abnormal_ear_morphology | 0.62068178 |
| 93 | MP0002876_abnormal_thyroid_physiology | 0.61986904 |
| 94 | MP0003279_aneurysm | 0.61590123 |
| 95 | MP0004133_heterotaxia | 0.60149952 |
| 96 | MP0002063_abnormal_learning/memory/cond | 0.59893337 |
| 97 | MP0001486_abnormal_startle_reflex | 0.59431477 |
| 98 | MP0000026_abnormal_inner_ear | 0.59217048 |
| 99 | MP0003938_abnormal_ear_development | 0.59033805 |
| 100 | MP0001873_stomach_inflammation | 0.57830663 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 6.63488330 |
| 2 | Reticulocytopenia (HP:0001896) | 5.85194981 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.60607688 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 5.09707611 |
| 5 | Abnormal number of erythroid precursors (HP:0012131) | 4.64218611 |
| 6 | Macrocytic anemia (HP:0001972) | 4.62691876 |
| 7 | Abnormal rod and cone electroretinograms (HP:0008323) | 4.56813202 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.53168218 |
| 9 | Chronic hepatic failure (HP:0100626) | 4.49384581 |
| 10 | Acute encephalopathy (HP:0006846) | 4.24559470 |
| 11 | Mitochondrial inheritance (HP:0001427) | 4.24139725 |
| 12 | Progressive macrocephaly (HP:0004481) | 4.06732030 |
| 13 | Pendular nystagmus (HP:0012043) | 3.81017196 |
| 14 | Pallor (HP:0000980) | 3.69676473 |
| 15 | Decreased central vision (HP:0007663) | 3.63902214 |
| 16 | Increased CSF lactate (HP:0002490) | 3.55581836 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.37308937 |
| 18 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.24627003 |
| 19 | Absent/shortened dynein arms (HP:0200106) | 3.24627003 |
| 20 | Increased hepatocellular lipid droplets (HP:0006565) | 3.19642463 |
| 21 | Septo-optic dysplasia (HP:0100842) | 3.13496109 |
| 22 | Cerebral edema (HP:0002181) | 3.12003705 |
| 23 | Optic disc pallor (HP:0000543) | 3.03722805 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.96694979 |
| 25 | Abnormality of midbrain morphology (HP:0002418) | 2.96694979 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.93989718 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.93541148 |
| 28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.87068033 |
| 29 | True hermaphroditism (HP:0010459) | 2.83952601 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.82404724 |
| 31 | Anencephaly (HP:0002323) | 2.74284009 |
| 32 | Hepatic necrosis (HP:0002605) | 2.73788458 |
| 33 | Agitation (HP:0000713) | 2.71980244 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.54156511 |
| 35 | Adrenal hypoplasia (HP:0000835) | 2.49292226 |
| 36 | Congenital stationary night blindness (HP:0007642) | 2.48966493 |
| 37 | Keratoconus (HP:0000563) | 2.42965169 |
| 38 | Increased corneal curvature (HP:0100692) | 2.42965169 |
| 39 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.40260133 |
| 40 | 3-Methylglutaconic aciduria (HP:0003535) | 2.39061778 |
| 41 | Pancreatic cysts (HP:0001737) | 2.38013549 |
| 42 | Increased serum lactate (HP:0002151) | 2.36709954 |
| 43 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.35055782 |
| 44 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.35055782 |
| 45 | Stenosis of the external auditory canal (HP:0000402) | 2.32874153 |
| 46 | Cystic liver disease (HP:0006706) | 2.28863710 |
| 47 | Dyskinesia (HP:0100660) | 2.25460948 |
| 48 | Leukodystrophy (HP:0002415) | 2.24843063 |
| 49 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.24329659 |
| 50 | Abnormality of alanine metabolism (HP:0010916) | 2.24329659 |
| 51 | Hyperalaninemia (HP:0003348) | 2.24329659 |
| 52 | Abnormality of renal resorption (HP:0011038) | 2.23338929 |
| 53 | Sclerocornea (HP:0000647) | 2.21794047 |
| 54 | Depressed nasal ridge (HP:0000457) | 2.21076679 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.20696346 |
| 56 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.20100040 |
| 57 | Abnormal ciliary motility (HP:0012262) | 2.18347816 |
| 58 | Respiratory failure (HP:0002878) | 2.16127392 |
| 59 | Cerebral hypomyelination (HP:0006808) | 2.15509052 |
| 60 | 11 pairs of ribs (HP:0000878) | 2.14090580 |
| 61 | Type II lissencephaly (HP:0007260) | 2.13720248 |
| 62 | Increased muscle lipid content (HP:0009058) | 2.10671889 |
| 63 | Attenuation of retinal blood vessels (HP:0007843) | 2.10113478 |
| 64 | Disinhibition (HP:0000734) | 2.07442351 |
| 65 | Hypogonadotrophic hypogonadism (HP:0000044) | 2.07296383 |
| 66 | Hyperglycinemia (HP:0002154) | 2.06978612 |
| 67 | Absent thumb (HP:0009777) | 2.04914223 |
| 68 | Myokymia (HP:0002411) | 2.00936849 |
| 69 | Asplenia (HP:0001746) | 1.99709809 |
| 70 | Exertional dyspnea (HP:0002875) | 1.98293741 |
| 71 | Abnormality of magnesium homeostasis (HP:0004921) | 1.97022028 |
| 72 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.96287024 |
| 73 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.96082512 |
| 74 | Restlessness (HP:0000711) | 1.96014981 |
| 75 | Lactic acidosis (HP:0003128) | 1.95188731 |
| 76 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.93970357 |
| 77 | Exercise intolerance (HP:0003546) | 1.93452577 |
| 78 | Hyperphosphaturia (HP:0003109) | 1.92827685 |
| 79 | Abnormal hemoglobin (HP:0011902) | 1.92556960 |
| 80 | Maternal diabetes (HP:0009800) | 1.90828091 |
| 81 | Colon cancer (HP:0003003) | 1.89324523 |
| 82 | Abolished electroretinogram (ERG) (HP:0000550) | 1.88975856 |
| 83 | Growth hormone deficiency (HP:0000824) | 1.85548266 |
| 84 | Hypoplasia of the radius (HP:0002984) | 1.83387248 |
| 85 | Testicular atrophy (HP:0000029) | 1.81333647 |
| 86 | Postaxial foot polydactyly (HP:0001830) | 1.80766574 |
| 87 | Anosmia (HP:0000458) | 1.78022156 |
| 88 | Abnormality of the labia minora (HP:0012880) | 1.74652027 |
| 89 | Lissencephaly (HP:0001339) | 1.74282415 |
| 90 | Optic nerve hypoplasia (HP:0000609) | 1.74223380 |
| 91 | Lethargy (HP:0001254) | 1.73796010 |
| 92 | Partial duplication of thumb phalanx (HP:0009944) | 1.73766517 |
| 93 | Hypoplasia of the ulna (HP:0003022) | 1.71963148 |
| 94 | Irregular epiphyses (HP:0010582) | 1.69743312 |
| 95 | Hyperthyroidism (HP:0000836) | 1.69184236 |
| 96 | Premature ovarian failure (HP:0008209) | 1.68992206 |
| 97 | Respiratory difficulties (HP:0002880) | 1.68350032 |
| 98 | Anophthalmia (HP:0000528) | 1.67750305 |
| 99 | Nephronophthisis (HP:0000090) | 1.67437303 |
| 100 | Short femoral neck (HP:0100864) | 1.66922205 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PASK | 6.22116490 |
| 2 | NME2 | 3.84559662 |
| 3 | LRRK2 | 3.13531811 |
| 4 | CAMKK1 | 3.03147663 |
| 5 | STK16 | 2.54919775 |
| 6 | DYRK2 | 2.27137405 |
| 7 | MAP3K13 | 2.20326680 |
| 8 | MAP4K1 | 2.03828202 |
| 9 | WNK4 | 2.02308338 |
| 10 | TXK | 2.01672440 |
| 11 | MAP3K11 | 1.96785843 |
| 12 | TYRO3 | 1.90224458 |
| 13 | WNK3 | 1.89976350 |
| 14 | PIK3CA | 1.88258615 |
| 15 | BCKDK | 1.87353599 |
| 16 | ADRBK2 | 1.82983162 |
| 17 | RIPK4 | 1.78228296 |
| 18 | EPHB2 | 1.78076299 |
| 19 | GRK1 | 1.65754457 |
| 20 | BMPR1B | 1.61093055 |
| 21 | TIE1 | 1.58351141 |
| 22 | CAMKK2 | 1.45949756 |
| 23 | ZAK | 1.40401127 |
| 24 | CDC7 | 1.38468163 |
| 25 | CASK | 1.36721508 |
| 26 | BRAF | 1.28865188 |
| 27 | PLK4 | 1.18330788 |
| 28 | NTRK2 | 1.15240613 |
| 29 | AKT3 | 1.14521512 |
| 30 | PINK1 | 1.09330610 |
| 31 | MAP4K2 | 1.08636632 |
| 32 | PRKCG | 1.07620405 |
| 33 | EPHA4 | 1.06048464 |
| 34 | PRKCQ | 0.97810085 |
| 35 | NEK1 | 0.94859551 |
| 36 | PDK2 | 0.93177906 |
| 37 | SGK494 | 0.92271684 |
| 38 | SGK223 | 0.92271684 |
| 39 | INSRR | 0.91669287 |
| 40 | PTK6 | 0.91511320 |
| 41 | NTRK3 | 0.87680943 |
| 42 | TLK1 | 0.85602005 |
| 43 | NEK2 | 0.85582721 |
| 44 | STK11 | 0.85434671 |
| 45 | CAMK1 | 0.81073250 |
| 46 | TEC | 0.81019185 |
| 47 | AURKA | 0.80018160 |
| 48 | TRIM28 | 0.78657269 |
| 49 | SIK2 | 0.76160326 |
| 50 | EIF2AK1 | 0.75839104 |
| 51 | ADRBK1 | 0.74459443 |
| 52 | KDR | 0.73876687 |
| 53 | STK39 | 0.72953033 |
| 54 | PRKCZ | 0.72558988 |
| 55 | PIM2 | 0.70854535 |
| 56 | IKBKB | 0.70356311 |
| 57 | PRKACA | 0.70038850 |
| 58 | BTK | 0.68937012 |
| 59 | MARK3 | 0.67687774 |
| 60 | ITK | 0.66996486 |
| 61 | MAP3K4 | 0.65725969 |
| 62 | CSNK2A2 | 0.65480667 |
| 63 | OBSCN | 0.64840126 |
| 64 | GRK7 | 0.64702672 |
| 65 | ABL2 | 0.63009466 |
| 66 | BRSK1 | 0.62502987 |
| 67 | CAMK1D | 0.61463536 |
| 68 | MAPK13 | 0.60408942 |
| 69 | PLK1 | 0.60213887 |
| 70 | TNIK | 0.58542102 |
| 71 | FRK | 0.57397906 |
| 72 | MAPK15 | 0.57139061 |
| 73 | MINK1 | 0.56526754 |
| 74 | PHKG2 | 0.55520277 |
| 75 | PHKG1 | 0.55520277 |
| 76 | RPS6KA6 | 0.53239334 |
| 77 | KIT | 0.51366954 |
| 78 | SGK1 | 0.50445847 |
| 79 | RPS6KA5 | 0.50293041 |
| 80 | SYK | 0.48834619 |
| 81 | PRKCI | 0.47995175 |
| 82 | TGFBR1 | 0.46879053 |
| 83 | PAK1 | 0.46080656 |
| 84 | LCK | 0.46040649 |
| 85 | MKNK2 | 0.45844408 |
| 86 | PRKCA | 0.43890171 |
| 87 | LIMK1 | 0.43176512 |
| 88 | PRKCD | 0.42954322 |
| 89 | CSNK2A1 | 0.42598417 |
| 90 | MUSK | 0.41650541 |
| 91 | AURKB | 0.41241829 |
| 92 | PIM1 | 0.40688881 |
| 93 | PRKACG | 0.38769541 |
| 94 | CAMK1G | 0.37400601 |
| 95 | CSNK1E | 0.37011643 |
| 96 | STK4 | 0.33778231 |
| 97 | IKBKE | 0.32501433 |
| 98 | DYRK3 | 0.32472929 |
| 99 | RPS6KL1 | 0.32082965 |
| 100 | RPS6KC1 | 0.32082965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 8.73505012 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.53598880 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.89716740 |
| 4 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.83880108 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.74110615 |
| 6 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.59549935 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.56350427 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.42920886 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.12790861 |
| 10 | RNA degradation_Homo sapiens_hsa03018 | 1.80507865 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.65728003 |
| 12 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.65402239 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.55627514 |
| 14 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.50277799 |
| 15 | Proteasome_Homo sapiens_hsa03050 | 1.42014728 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.40764434 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.23811308 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.23547864 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.21842785 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.18395317 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.16151151 |
| 22 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12667731 |
| 23 | Sulfur relay system_Homo sapiens_hsa04122 | 1.11071372 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.10958695 |
| 25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.09219606 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.08723588 |
| 27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96969719 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.95224319 |
| 29 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.94572504 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92474941 |
| 31 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.91442462 |
| 32 | Olfactory transduction_Homo sapiens_hsa04740 | 0.85309760 |
| 33 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.83833234 |
| 34 | Nicotine addiction_Homo sapiens_hsa05033 | 0.83592176 |
| 35 | Morphine addiction_Homo sapiens_hsa05032 | 0.80390570 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 0.78356189 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.77557116 |
| 38 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.77201726 |
| 39 | DNA replication_Homo sapiens_hsa03030 | 0.75882862 |
| 40 | Homologous recombination_Homo sapiens_hsa03440 | 0.75326873 |
| 41 | Asthma_Homo sapiens_hsa05310 | 0.74322207 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.72751989 |
| 43 | Base excision repair_Homo sapiens_hsa03410 | 0.72174646 |
| 44 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.71745718 |
| 45 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70205951 |
| 46 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68587441 |
| 47 | Basal transcription factors_Homo sapiens_hsa03022 | 0.68263289 |
| 48 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.68217898 |
| 49 | Insulin secretion_Homo sapiens_hsa04911 | 0.67417945 |
| 50 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.64212516 |
| 51 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.61569154 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.59708231 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.59315798 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58647000 |
| 55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.58606147 |
| 56 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.57667074 |
| 57 | Mismatch repair_Homo sapiens_hsa03430 | 0.49743739 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49634542 |
| 59 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.49298237 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.49049697 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48984325 |
| 62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.48912283 |
| 63 | Cocaine addiction_Homo sapiens_hsa05030 | 0.47987059 |
| 64 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.47540224 |
| 65 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.46707809 |
| 66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.46178557 |
| 67 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.45881822 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43312042 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.42624065 |
| 70 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.42457911 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42168841 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41274390 |
| 73 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.39186313 |
| 74 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.38652922 |
| 75 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.37815577 |
| 76 | Allograft rejection_Homo sapiens_hsa05330 | 0.36278864 |
| 77 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.35651270 |
| 78 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34232881 |
| 79 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33709159 |
| 80 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.33704177 |
| 81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.33197663 |
| 82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.33140678 |
| 83 | Galactose metabolism_Homo sapiens_hsa00052 | 0.32986249 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.32157166 |
| 85 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32135893 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32042641 |
| 87 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.32041555 |
| 88 | Spliceosome_Homo sapiens_hsa03040 | 0.31535704 |
| 89 | RNA transport_Homo sapiens_hsa03013 | 0.29933247 |
| 90 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.28994469 |
| 91 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.28876933 |
| 92 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.26850540 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.25464629 |
| 94 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.25386831 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.23830662 |
| 96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.23135699 |
| 97 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.22261523 |
| 98 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.20914049 |
| 99 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.20753468 |
| 100 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.19659959 |

