RPL7AP31

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.74167311
2translational termination (GO:0006415)7.47383914
3maturation of SSU-rRNA (GO:0030490)7.16569271
4ribosomal small subunit biogenesis (GO:0042274)6.48763259
5translational elongation (GO:0006414)6.46066058
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.13405961
7cotranslational protein targeting to membrane (GO:0006613)6.01061195
8protein targeting to ER (GO:0045047)5.99904365
9dopamine transport (GO:0015872)5.82033764
10establishment of protein localization to endoplasmic reticulum (GO:0072599)5.67032687
11cellular protein complex disassembly (GO:0043624)5.59738078
12protein localization to endoplasmic reticulum (GO:0070972)5.58335963
13viral life cycle (GO:0019058)5.51581650
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.41870652
15regulation of isotype switching to IgG isotypes (GO:0048302)5.19679687
16ribosomal small subunit assembly (GO:0000028)5.13257287
17lens fiber cell development (GO:0070307)4.98455325
18antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.94477658
19chaperone-mediated protein transport (GO:0072321)4.89402068
20pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.83241033
21nucleoside transmembrane transport (GO:1901642)4.78105483
22translational initiation (GO:0006413)4.77167534
23ATP synthesis coupled proton transport (GO:0015986)4.73213855
24energy coupled proton transport, down electrochemical gradient (GO:0015985)4.73213855
25behavioral response to nicotine (GO:0035095)4.72773181
26base-excision repair, AP site formation (GO:0006285)4.69893269
27antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.64842027
28protein complex disassembly (GO:0043241)4.61619446
29ribosomal large subunit biogenesis (GO:0042273)4.33465323
30macromolecular complex disassembly (GO:0032984)4.27374359
31positive regulation of defense response to virus by host (GO:0002230)4.22325924
32pyrimidine nucleotide catabolic process (GO:0006244)4.14749789
33translation (GO:0006412)4.04002300
34nuclear-transcribed mRNA catabolic process (GO:0000956)3.97299655
35protein targeting to membrane (GO:0006612)3.92966719
36male meiosis I (GO:0007141)3.89485588
37regulation of memory T cell differentiation (GO:0043380)3.83498593
38antigen processing and presentation of endogenous antigen (GO:0019883)3.78202478
39positive regulation of isotype switching (GO:0045830)3.72909479
40response to pheromone (GO:0019236)3.71355154
41mRNA catabolic process (GO:0006402)3.68613100
42activated T cell proliferation (GO:0050798)3.67073891
43interferon-gamma production (GO:0032609)3.59034003
44exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.58829122
45nucleoside transport (GO:0015858)3.57919922
46DNA deamination (GO:0045006)3.57783406
47positive regulation of DNA recombination (GO:0045911)3.51399728
48nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.50384774
49mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.45335252
50nucleobase biosynthetic process (GO:0046112)3.45313481
51positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.40316615
52ribonucleoprotein complex biogenesis (GO:0022613)3.37093134
53synapsis (GO:0007129)3.32019008
54L-fucose catabolic process (GO:0042355)3.29506698
55fucose catabolic process (GO:0019317)3.29506698
56L-fucose metabolic process (GO:0042354)3.29506698
57tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.28198804
58RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.28198804
59RNA catabolic process (GO:0006401)3.24497854
60deoxyribonucleotide catabolic process (GO:0009264)3.19448563
61catecholamine transport (GO:0051937)3.18280674
62cellular component biogenesis (GO:0044085)3.11016794
63pyrimidine nucleoside monophosphate metabolic process (GO:0009129)3.03795288
64organic cation transport (GO:0015695)3.02068709
65mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.00629517
66meiosis I (GO:0007127)2.98847526
67pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.98326103
68rRNA processing (GO:0006364)2.98186937
69transmission of nerve impulse (GO:0019226)2.97184989
70pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.94732054
71regulation of activation of Janus kinase activity (GO:0010533)2.94331134
72regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.91660942
73positive regulation of cell fate commitment (GO:0010455)2.91461855
74positive regulation of B cell mediated immunity (GO:0002714)2.89471595
75positive regulation of immunoglobulin mediated immune response (GO:0002891)2.89471595
76deoxyribose phosphate catabolic process (GO:0046386)2.88595390
77pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.87937367
78UMP metabolic process (GO:0046049)2.87937367
79pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.87937367
80UMP biosynthetic process (GO:0006222)2.87937367
81positive regulation of icosanoid secretion (GO:0032305)2.86294218
82rRNA metabolic process (GO:0016072)2.85835325
83positive regulation of T-helper 1 type immune response (GO:0002827)2.84478755
84leukotriene biosynthetic process (GO:0019370)2.82985428
85protein complex biogenesis (GO:0070271)2.79499825
86positive regulation of fatty acid transport (GO:2000193)2.79106060
87establishment of protein localization to mitochondrial membrane (GO:0090151)2.78826152
88lymphocyte migration (GO:0072676)2.78350081
89GTP biosynthetic process (GO:0006183)2.77334446
90positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.75412732
91valine metabolic process (GO:0006573)2.74873356
92positive regulation of immunoglobulin production (GO:0002639)2.74048415
93arginine catabolic process (GO:0006527)2.72678056
94purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.70911632
95regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.70044437
96ATP biosynthetic process (GO:0006754)2.68883375
97heart trabecula morphogenesis (GO:0061384)2.68035205
98branched-chain amino acid catabolic process (GO:0009083)2.66038944
99protein neddylation (GO:0045116)2.64433776
100purine nucleoside triphosphate biosynthetic process (GO:0009145)2.64398363

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.34432604
2ZNF274_21170338_ChIP-Seq_K562_Hela3.21408358
3ELF1_17652178_ChIP-ChIP_JURKAT_Human3.12890630
4CHD7_19251738_ChIP-ChIP_MESCs_Mouse3.03263271
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.81183556
6EZH2_22144423_ChIP-Seq_EOC_Human2.64493162
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.61038843
8CREB1_15753290_ChIP-ChIP_HEK293T_Human2.34517799
9HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.31707654
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.30707978
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16508661
12VDR_22108803_ChIP-Seq_LS180_Human2.15568610
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.14731399
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.14420201
15BMI1_23680149_ChIP-Seq_NPCS_Mouse2.10130477
16STAT6_21828071_ChIP-Seq_BEAS2B_Human2.03927786
17IRF1_19129219_ChIP-ChIP_H3396_Human1.99027017
18ETS1_20019798_ChIP-Seq_JURKAT_Human1.90677624
19CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.90017721
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.89056841
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.86322995
22JARID2_20064375_ChIP-Seq_MESCs_Mouse1.67260705
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.67252998
24VDR_23849224_ChIP-Seq_CD4+_Human1.65975742
25TP53_22573176_ChIP-Seq_HFKS_Human1.60438084
26TAF2_19829295_ChIP-Seq_ESCs_Human1.57192172
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.56580349
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.55585847
29EWS_26573619_Chip-Seq_HEK293_Human1.54761805
30YY1_21170310_ChIP-Seq_MESCs_Mouse1.52161735
31MYC_19079543_ChIP-ChIP_MESCs_Mouse1.46844555
32SUZ12_27294783_Chip-Seq_ESCs_Mouse1.46837832
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.45781648
34SOX2_18555785_ChIP-Seq_MESCs_Mouse1.45516587
35GATA3_21878914_ChIP-Seq_MCF-7_Human1.43686406
36EGR1_23403033_ChIP-Seq_LIVER_Mouse1.43003531
37EZH2_27294783_Chip-Seq_ESCs_Mouse1.42268622
38MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42084700
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38867378
40EZH2_27304074_Chip-Seq_ESCs_Mouse1.35815164
41LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.35346895
42CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.31400231
43SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.31059170
44HTT_18923047_ChIP-ChIP_STHdh_Human1.30707051
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.28952195
46JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.26318468
47IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.25862222
48BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.25344144
49NANOG_20526341_ChIP-Seq_ESCs_Human1.25336356
50NANOG_19829295_ChIP-Seq_ESCs_Human1.25179681
51SOX2_19829295_ChIP-Seq_ESCs_Human1.25179681
52GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.25142345
53RNF2_27304074_Chip-Seq_NSC_Mouse1.22528807
54EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.22363832
55MYC_18555785_ChIP-Seq_MESCs_Mouse1.21961520
56RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.20545433
57MYC_18940864_ChIP-ChIP_HL60_Human1.20489472
58CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.16846046
59E2F1_20622854_ChIP-Seq_HELA_Human1.16786499
60EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15549394
61BCAT_22108803_ChIP-Seq_LS180_Human1.15443670
62VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.15271810
63JARID2_20075857_ChIP-Seq_MESCs_Mouse1.15188610
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.14574036
65FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12381041
66FOXA1_25329375_ChIP-Seq_VCAP_Human1.12381041
67ELK1_19687146_ChIP-ChIP_HELA_Human1.11057612
68CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10423428
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.09884974
70NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09399740
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.08632319
72ERA_21632823_ChIP-Seq_H3396_Human1.08000000
73FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07843515
74AR_21572438_ChIP-Seq_LNCaP_Human1.07642152
75REST_21632747_ChIP-Seq_MESCs_Mouse1.07627779
76GATA1_26923725_Chip-Seq_HPCs_Mouse1.06787715
77IKZF1_21737484_ChIP-ChIP_HCT116_Human1.06753660
78PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.06245085
79SA1_27219007_Chip-Seq_Bcells_Human1.05879352
80CBX2_27304074_Chip-Seq_ESCs_Mouse1.05240262
81SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.05237298
82CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.05234548
83YY1_22570637_ChIP-Seq_MALME-3M_Human1.04943879
84CTCF_20526341_ChIP-Seq_ESCs_Human1.04908250
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.03574695
86ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03214432
87IRF8_22096565_ChIP-ChIP_GC-B_Human1.02678935
88AUTS2_25519132_ChIP-Seq_293T-REX_Human1.01887903
89AR_20517297_ChIP-Seq_VCAP_Human1.00026024
90IGF1R_20145208_ChIP-Seq_DFB_Human0.99147869
91ERG_20517297_ChIP-Seq_VCAP_Human0.98752957
92RNF2_18974828_ChIP-Seq_MESCs_Mouse0.98666960
93EZH2_18974828_ChIP-Seq_MESCs_Mouse0.98666960
94GATA3_26560356_Chip-Seq_TH2_Human0.98189095
95BCL6_27268052_Chip-Seq_Bcells_Human0.97992506
96GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.97982644
97FOXH1_21741376_ChIP-Seq_ESCs_Human0.97206107
98MYC_19829295_ChIP-Seq_ESCs_Human0.95524092
99XRN2_22483619_ChIP-Seq_HELA_Human0.95070434
100PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.94819451

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.05277914
2MP0002132_abnormal_respiratory_system3.99107956
3MP0003646_muscle_fatigue3.80905903
4MP0006082_CNS_inflammation3.72219821
5MP0005671_abnormal_response_to3.28547751
6MP0001835_abnormal_antigen_presentation2.77812707
7MP0006292_abnormal_olfactory_placode2.72353308
8MP0002736_abnormal_nociception_after2.30234309
9MP0001529_abnormal_vocalization2.20182894
10MP0002638_abnormal_pupillary_reflex2.13058425
11MP0004885_abnormal_endolymph1.99909646
12MP0008875_abnormal_xenobiotic_pharmacok1.98751829
13MP0001986_abnormal_taste_sensitivity1.93299316
14MP0001968_abnormal_touch/_nociception1.93243001
15MP0002837_dystrophic_cardiac_calcinosis1.87155220
16MP0002160_abnormal_reproductive_system1.81610661
17MP0003195_calcinosis1.78226814
18MP0004145_abnormal_muscle_electrophysio1.71640491
19MP0001663_abnormal_digestive_system1.69433208
20MP0009785_altered_susceptibility_to1.66365823
21MP0006072_abnormal_retinal_apoptosis1.64500024
22MP0010155_abnormal_intestine_physiology1.61516209
23MP0001800_abnormal_humoral_immune1.60707792
24MP0005389_reproductive_system_phenotype1.59001678
25MP0001873_stomach_inflammation1.58625748
26MP0003252_abnormal_bile_duct1.56868013
27MP0001790_abnormal_immune_system1.55214354
28MP0005387_immune_system_phenotype1.55214354
29MP0005360_urolithiasis1.53865579
30MP0004142_abnormal_muscle_tone1.53665406
31MP0000858_altered_metastatic_potential1.43254740
32MP0002138_abnormal_hepatobiliary_system1.36792174
33MP0008872_abnormal_physiological_respon1.33484816
34MP0005377_hearing/vestibular/ear_phenot1.33456086
35MP0003878_abnormal_ear_physiology1.33456086
36MP0001348_abnormal_lacrimal_gland1.31998319
37MP0003718_maternal_effect1.31251855
38MP0008789_abnormal_olfactory_epithelium1.27973772
39MP0008775_abnormal_heart_ventricle1.27878752
40MP0005408_hypopigmentation1.26821279
41MP0005000_abnormal_immune_tolerance1.25257094
42MP0005551_abnormal_eye_electrophysiolog1.19574557
43MP0003011_delayed_dark_adaptation1.18763803
44MP0005167_abnormal_blood-brain_barrier1.17657512
45MP0002723_abnormal_immune_serum1.15970812
46MP0005381_digestive/alimentary_phenotyp1.15312248
47MP0001919_abnormal_reproductive_system1.14137513
48MP0002102_abnormal_ear_morphology1.14039350
49MP0005645_abnormal_hypothalamus_physiol1.13677719
50MP0002163_abnormal_gland_morphology1.08439097
51MP0000049_abnormal_middle_ear1.06718319
52MP0000631_abnormal_neuroendocrine_gland1.06017188
53MP0002405_respiratory_system_inflammati1.05580776
54MP0005646_abnormal_pituitary_gland1.05136724
55MP0000685_abnormal_immune_system1.03727221
56MP0009745_abnormal_behavioral_response1.03367380
57MP0004036_abnormal_muscle_relaxation1.00998576
58MP0004742_abnormal_vestibular_system1.00282315
59MP0003567_abnormal_fetal_cardiomyocyte0.94961072
60MP0002210_abnormal_sex_determination0.94563333
61MP0002452_abnormal_antigen_presenting0.94496781
62MP0001905_abnormal_dopamine_level0.93814679
63MP0004782_abnormal_surfactant_physiolog0.93205486
64MP0005025_abnormal_response_to0.92963637
65MP0002272_abnormal_nervous_system0.92495985
66MP0001984_abnormal_olfaction0.92064583
67MP0009333_abnormal_splenocyte_physiolog0.91925666
68MP0002420_abnormal_adaptive_immunity0.89032577
69MP0008877_abnormal_DNA_methylation0.88950085
70MP0005253_abnormal_eye_physiology0.88135680
71MP0003879_abnormal_hair_cell0.87795583
72MP0001819_abnormal_immune_cell0.87743903
73MP0003119_abnormal_digestive_system0.87310815
74MP0004043_abnormal_pH_regulation0.86850095
75MP0002876_abnormal_thyroid_physiology0.86751642
76MP0005394_taste/olfaction_phenotype0.84321541
77MP0005499_abnormal_olfactory_system0.84321541
78MP0009764_decreased_sensitivity_to0.82852296
79MP0001119_abnormal_female_reproductive0.81537053
80MP0001970_abnormal_pain_threshold0.80532974
81MP0004147_increased_porphyrin_level0.79243086
82MP0003137_abnormal_impulse_conducting0.79236907
83MP0003936_abnormal_reproductive_system0.79148805
84MP0001845_abnormal_inflammatory_respons0.76299794
85MP0003136_yellow_coat_color0.76295735
86MP0008469_abnormal_protein_level0.75675121
87MP0005410_abnormal_fertilization0.75659707
88MP0001727_abnormal_embryo_implantation0.75001118
89MP0002733_abnormal_thermal_nociception0.74097559
90MP0005195_abnormal_posterior_eye0.73533904
91MP0002184_abnormal_innervation0.73039222
92MP0009697_abnormal_copulation0.72241162
93MP0002735_abnormal_chemical_nociception0.69704193
94MP0005379_endocrine/exocrine_gland_phen0.67977212
95MP0009250_abnormal_appendicular_skeleto0.67424862
96MP0001485_abnormal_pinna_reflex0.67403378
97MP0002933_joint_inflammation0.66652667
98MP0000490_abnormal_crypts_of0.66561987
99MP0002277_abnormal_respiratory_mucosa0.66427618
100MP0002095_abnormal_skin_pigmentation0.66360890

Predicted human phenotypes

RankGene SetZ-score
1Nasal polyposis (HP:0100582)8.52488983
2Abnormality of the nasal mucosa (HP:0000433)7.01548055
3Chronic otitis media (HP:0000389)6.07206216
4Absent rod-and cone-mediated responses on ERG (HP:0007688)4.22219204
5Chronic sinusitis (HP:0011109)4.14799690
6Macrocytic anemia (HP:0001972)4.13772131
7Abnormal rod and cone electroretinograms (HP:0008323)3.87254708
8Recurrent bronchitis (HP:0002837)3.76256238
9Elevated erythrocyte sedimentation rate (HP:0003565)3.55146768
10Hypothermia (HP:0002045)3.43397005
11Pallor (HP:0000980)3.14091775
12Zonular cataract (HP:0010920)3.05413897
13Congenital stationary night blindness (HP:0007642)2.83537733
14Acanthocytosis (HP:0001927)2.82322466
15Conjugated hyperbilirubinemia (HP:0002908)2.79117224
16Parakeratosis (HP:0001036)2.78354458
17Colon cancer (HP:0003003)2.77655530
18Abnormality of cells of the erythroid lineage (HP:0012130)2.77189822
19Lipid accumulation in hepatocytes (HP:0006561)2.73135663
20Decreased central vision (HP:0007663)2.72425542
21Poikilocytosis (HP:0004447)2.72405261
22Abnormality of pyrimidine metabolism (HP:0004353)2.72321379
23Dyskinesia (HP:0100660)2.72319754
24Agitation (HP:0000713)2.68945340
25Pendular nystagmus (HP:0012043)2.66790337
26Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.54010300
27Abnormality of alanine metabolism (HP:0010916)2.54010300
28Hyperalaninemia (HP:0003348)2.54010300
29Acute necrotizing encephalopathy (HP:0006965)2.49639826
30Attenuation of retinal blood vessels (HP:0007843)2.49524406
313-Methylglutaconic aciduria (HP:0003535)2.48992208
32Bronchitis (HP:0012387)2.48896411
33Hemiplegia (HP:0002301)2.43752596
34Cerebral hypomyelination (HP:0006808)2.42858651
35Megaloblastic anemia (HP:0001889)2.40633269
36Mitochondrial inheritance (HP:0001427)2.33830106
37Septo-optic dysplasia (HP:0100842)2.25276974
38IgG deficiency (HP:0004315)2.23352375
39Hypoproteinemia (HP:0003075)2.23107650
40Bony spicule pigmentary retinopathy (HP:0007737)2.22546076
41Congenital sensorineural hearing impairment (HP:0008527)2.22105389
42Abnormality of midbrain morphology (HP:0002418)2.19905515
43Molar tooth sign on MRI (HP:0002419)2.19905515
44Absent thumb (HP:0009777)2.18346302
45Abnormality of T cell physiology (HP:0011840)2.16986186
46Personality changes (HP:0000751)2.16891605
47Thrombocytosis (HP:0001894)2.15981502
48Increased CSF lactate (HP:0002490)2.11425241
49Abnormality of the phalanges of the 2nd finger (HP:0009541)2.11197132
50Reticulocytopenia (HP:0001896)2.11118784
51Decreased activity of mitochondrial respiratory chain (HP:0008972)2.10605611
52Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.10605611
53Global brain atrophy (HP:0002283)2.08171305
54Degeneration of anterior horn cells (HP:0002398)2.08129594
55Abnormality of the anterior horn cell (HP:0006802)2.08129594
56Progressive macrocephaly (HP:0004481)2.07570099
57Abnormal mitochondria in muscle tissue (HP:0008316)2.07367328
58Exertional dyspnea (HP:0002875)2.06863998
59Type 2 muscle fiber atrophy (HP:0003554)2.05000500
60Medial flaring of the eyebrow (HP:0010747)2.04668554
61Abnormality of T cells (HP:0002843)2.03917110
62Acute encephalopathy (HP:0006846)2.02569111
63Myositis (HP:0100614)2.00546861
64Abnormality of monocarboxylic acid metabolism (HP:0010996)1.99430121
65Increased hepatocellular lipid droplets (HP:0006565)1.99173475
66Abnormal number of erythroid precursors (HP:0012131)1.98426221
67Delayed CNS myelination (HP:0002188)1.97704563
68Increased corneal curvature (HP:0100692)1.97149814
69Keratoconus (HP:0000563)1.97149814
70Stomatitis (HP:0010280)1.96998478
71Erythroderma (HP:0001019)1.96871849
72Congenital, generalized hypertrichosis (HP:0004540)1.95452000
73Hepatocellular necrosis (HP:0001404)1.92449188
74Abnormal number of incisors (HP:0011064)1.92422720
75Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.91026425
76Neurodegeneration (HP:0002180)1.86622233
77Esophageal neoplasm (HP:0100751)1.84381277
78Neoplasm of head and neck (HP:0012288)1.84381277
79Methylmalonic acidemia (HP:0002912)1.82109203
80Constricted visual fields (HP:0001133)1.81689119
81Muscle fiber atrophy (HP:0100295)1.80022371
82Abnormal hemoglobin (HP:0011902)1.75388497
83Restlessness (HP:0000711)1.73989355
84Clumsiness (HP:0002312)1.71358435
85Renal Fanconi syndrome (HP:0001994)1.69183649
86Optic nerve hypoplasia (HP:0000609)1.67403327
87Nephronophthisis (HP:0000090)1.67155467
88Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.66006485
89Stenosis of the external auditory canal (HP:0000402)1.65308594
90Emphysema (HP:0002097)1.64318975
91Stomach cancer (HP:0012126)1.63530546
92Methylmalonic aciduria (HP:0012120)1.63458268
93Lethargy (HP:0001254)1.62705651
94Bronchiectasis (HP:0002110)1.62478759
95Abnormality of the phalanges of the 5th finger (HP:0004213)1.62368140
96Optic disc pallor (HP:0000543)1.62217806
97Agammaglobulinemia (HP:0004432)1.62208328
98Nephrogenic diabetes insipidus (HP:0009806)1.62196797
99Palmoplantar hyperkeratosis (HP:0000972)1.60206241
100Short femoral neck (HP:0100864)1.60006212

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K135.81313341
2TLK14.36502261
3ITK3.16300562
4ADRBK22.96985928
5ERN12.94058539
6WNK42.59214723
7TXK2.50199953
8NME22.48542172
9TAOK32.39052301
10STK392.07880449
11MAP3K92.07858298
12ARAF1.78461120
13MAP2K21.69866279
14TIE11.62350467
15PTK2B1.53306166
16FRK1.52528512
17ZAP701.51377786
18GRK11.43047851
19WNK31.40481593
20BMPR21.40144464
21STK161.36169053
22BCKDK1.31514666
23MAP3K121.31287519
24INSRR1.23054021
25MAPK131.22628231
26BRAF1.21363737
27ADRBK11.18026962
28ILK1.12078004
29DYRK21.10287968
30MAP4K11.06731270
31PIM11.04932678
32FES1.04701567
33PDK21.02870779
34SYK1.02587889
35ZAK1.02143932
36LRRK20.95299129
37IKBKB0.94166779
38TBK10.92830225
39MAP4K20.89859057
40PRKG20.88099819
41BMPR1B0.87844406
42MOS0.86195941
43BTK0.85158930
44TEC0.84806305
45MAP3K80.79175676
46PRKCG0.78843643
47IKBKE0.78784756
48PIK3CA0.77755038
49ACVR1B0.76837842
50PRKCQ0.75710639
51OBSCN0.74354925
52VRK10.74284641
53PKN10.74236636
54RPS6KA50.74139637
55MYLK0.73776024
56PLK40.73366376
57NUAK10.73262328
58MUSK0.71753259
59MAP3K140.69774506
60PINK10.66781180
61PRKCZ0.65927549
62PASK0.65807106
63OXSR10.65413510
64GSK3A0.65294700
65MAP2K60.63513061
66CHEK20.62984648
67NEK10.60189868
68LCK0.59116929
69KDR0.59038676
70STK110.56837869
71PRKACA0.55401059
72MAP3K70.55177354
73CSNK1A10.54711419
74CSNK2A10.52992689
75WNK10.52352766
76HCK0.52262318
77GRK70.51320380
78PHKG20.50142898
79PHKG10.50142898
80MAPK70.49795240
81MAP2K10.49474288
82RPS6KA60.46215878
83PRKCA0.46188980
84CAMK2A0.43089745
85CSNK2A20.42715338
86CDK190.42082358
87JAK30.42033101
88EPHA20.40518567
89LYN0.40454237
90CAMK2D0.39867910
91IGF1R0.39804447
92RPS6KB20.39740296
93TGFBR10.38952961
94PRKACG0.38086002
95DAPK30.37375935
96CSNK1G30.35343995
97CDK40.34476907
98PRKCE0.33943794
99CAMK2G0.33875455
100AURKB0.31685390

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.51686576
2Graft-versus-host disease_Homo sapiens_hsa053323.49114103
3Oxidative phosphorylation_Homo sapiens_hsa001902.82950531
4Asthma_Homo sapiens_hsa053102.52220969
5Allograft rejection_Homo sapiens_hsa053302.49425407
6Parkinsons disease_Homo sapiens_hsa050122.37064706
7Autoimmune thyroid disease_Homo sapiens_hsa053202.35852698
8Linoleic acid metabolism_Homo sapiens_hsa005912.25454318
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.17528213
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.17490848
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.14213817
12Antigen processing and presentation_Homo sapiens_hsa046122.01842368
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.88419172
14Type I diabetes mellitus_Homo sapiens_hsa049401.85543870
15RNA degradation_Homo sapiens_hsa030181.80060194
16Drug metabolism - other enzymes_Homo sapiens_hsa009831.67822228
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.64404828
18Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.58237841
19Huntingtons disease_Homo sapiens_hsa050161.56252359
20Primary immunodeficiency_Homo sapiens_hsa053401.50169204
21Alzheimers disease_Homo sapiens_hsa050101.47643590
22Basal transcription factors_Homo sapiens_hsa030221.44498089
23RNA polymerase_Homo sapiens_hsa030201.43703498
24Proteasome_Homo sapiens_hsa030501.43249303
25Phototransduction_Homo sapiens_hsa047441.38986087
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.38822931
27Sulfur relay system_Homo sapiens_hsa041221.36945302
28Pyrimidine metabolism_Homo sapiens_hsa002401.35806941
29Olfactory transduction_Homo sapiens_hsa047401.35381444
30Cardiac muscle contraction_Homo sapiens_hsa042601.33346079
31Staphylococcus aureus infection_Homo sapiens_hsa051501.31283489
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29173480
33Homologous recombination_Homo sapiens_hsa034401.28812020
34Rheumatoid arthritis_Homo sapiens_hsa053231.27758445
35Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.27755155
36Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.24508048
37Caffeine metabolism_Homo sapiens_hsa002321.23924373
38Viral myocarditis_Homo sapiens_hsa054161.23250878
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18258944
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.15203159
41Arachidonic acid metabolism_Homo sapiens_hsa005901.12169597
42Base excision repair_Homo sapiens_hsa034101.12150543
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10684034
44Selenocompound metabolism_Homo sapiens_hsa004501.07833430
45Nicotine addiction_Homo sapiens_hsa050331.06401820
46Nitrogen metabolism_Homo sapiens_hsa009101.05431796
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.03043351
48Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.93995342
49Systemic lupus erythematosus_Homo sapiens_hsa053220.91508176
50Ether lipid metabolism_Homo sapiens_hsa005650.91156231
51Fat digestion and absorption_Homo sapiens_hsa049750.85448378
52Malaria_Homo sapiens_hsa051440.83877131
53Protein export_Homo sapiens_hsa030600.81939831
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.81526094
55Sulfur metabolism_Homo sapiens_hsa009200.81079028
56Chemical carcinogenesis_Homo sapiens_hsa052040.76624797
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.76016715
58Retinol metabolism_Homo sapiens_hsa008300.70986243
59NF-kappa B signaling pathway_Homo sapiens_hsa040640.69507616
60T cell receptor signaling pathway_Homo sapiens_hsa046600.68020658
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.67597363
62Hematopoietic cell lineage_Homo sapiens_hsa046400.63414112
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61505578
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61400935
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61392096
66Fanconi anemia pathway_Homo sapiens_hsa034600.61250337
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59261306
68Spliceosome_Homo sapiens_hsa030400.58908129
69Morphine addiction_Homo sapiens_hsa050320.58497646
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.57889153
71Fatty acid degradation_Homo sapiens_hsa000710.53911166
72Purine metabolism_Homo sapiens_hsa002300.53664570
73Taste transduction_Homo sapiens_hsa047420.53171470
74Leishmaniasis_Homo sapiens_hsa051400.52148867
75Pentose and glucuronate interconversions_Homo sapiens_hsa000400.51599284
76Metabolic pathways_Homo sapiens_hsa011000.45149774
77Tryptophan metabolism_Homo sapiens_hsa003800.42809857
78Collecting duct acid secretion_Homo sapiens_hsa049660.41542996
79Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39702298
80Nucleotide excision repair_Homo sapiens_hsa034200.36497951
81RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34465551
82Regulation of autophagy_Homo sapiens_hsa041400.32724967
83RNA transport_Homo sapiens_hsa030130.32006000
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.31351911
85Ovarian steroidogenesis_Homo sapiens_hsa049130.29083678
86Serotonergic synapse_Homo sapiens_hsa047260.25762312
87Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.24910363
88GABAergic synapse_Homo sapiens_hsa047270.24412094
89Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.22437149
90DNA replication_Homo sapiens_hsa030300.21780017
91Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.21558598
92Glycerophospholipid metabolism_Homo sapiens_hsa005640.21385853
93Insulin secretion_Homo sapiens_hsa049110.15144277
94One carbon pool by folate_Homo sapiens_hsa006700.14090409
95Calcium signaling pathway_Homo sapiens_hsa040200.12698598
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.12696350
97Hedgehog signaling pathway_Homo sapiens_hsa043400.12252394
98beta-Alanine metabolism_Homo sapiens_hsa004100.09524216
99Mineral absorption_Homo sapiens_hsa049780.08875132
100Glycerolipid metabolism_Homo sapiens_hsa005610.08800671

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »