

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 7.74167311 |
| 2 | translational termination (GO:0006415) | 7.47383914 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 7.16569271 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 6.48763259 |
| 5 | translational elongation (GO:0006414) | 6.46066058 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.13405961 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 6.01061195 |
| 8 | protein targeting to ER (GO:0045047) | 5.99904365 |
| 9 | dopamine transport (GO:0015872) | 5.82033764 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.67032687 |
| 11 | cellular protein complex disassembly (GO:0043624) | 5.59738078 |
| 12 | protein localization to endoplasmic reticulum (GO:0070972) | 5.58335963 |
| 13 | viral life cycle (GO:0019058) | 5.51581650 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.41870652 |
| 15 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.19679687 |
| 16 | ribosomal small subunit assembly (GO:0000028) | 5.13257287 |
| 17 | lens fiber cell development (GO:0070307) | 4.98455325 |
| 18 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.94477658 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 4.89402068 |
| 20 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.83241033 |
| 21 | nucleoside transmembrane transport (GO:1901642) | 4.78105483 |
| 22 | translational initiation (GO:0006413) | 4.77167534 |
| 23 | ATP synthesis coupled proton transport (GO:0015986) | 4.73213855 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.73213855 |
| 25 | behavioral response to nicotine (GO:0035095) | 4.72773181 |
| 26 | base-excision repair, AP site formation (GO:0006285) | 4.69893269 |
| 27 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.64842027 |
| 28 | protein complex disassembly (GO:0043241) | 4.61619446 |
| 29 | ribosomal large subunit biogenesis (GO:0042273) | 4.33465323 |
| 30 | macromolecular complex disassembly (GO:0032984) | 4.27374359 |
| 31 | positive regulation of defense response to virus by host (GO:0002230) | 4.22325924 |
| 32 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.14749789 |
| 33 | translation (GO:0006412) | 4.04002300 |
| 34 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.97299655 |
| 35 | protein targeting to membrane (GO:0006612) | 3.92966719 |
| 36 | male meiosis I (GO:0007141) | 3.89485588 |
| 37 | regulation of memory T cell differentiation (GO:0043380) | 3.83498593 |
| 38 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.78202478 |
| 39 | positive regulation of isotype switching (GO:0045830) | 3.72909479 |
| 40 | response to pheromone (GO:0019236) | 3.71355154 |
| 41 | mRNA catabolic process (GO:0006402) | 3.68613100 |
| 42 | activated T cell proliferation (GO:0050798) | 3.67073891 |
| 43 | interferon-gamma production (GO:0032609) | 3.59034003 |
| 44 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.58829122 |
| 45 | nucleoside transport (GO:0015858) | 3.57919922 |
| 46 | DNA deamination (GO:0045006) | 3.57783406 |
| 47 | positive regulation of DNA recombination (GO:0045911) | 3.51399728 |
| 48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.50384774 |
| 49 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.45335252 |
| 50 | nucleobase biosynthetic process (GO:0046112) | 3.45313481 |
| 51 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.40316615 |
| 52 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.37093134 |
| 53 | synapsis (GO:0007129) | 3.32019008 |
| 54 | L-fucose catabolic process (GO:0042355) | 3.29506698 |
| 55 | fucose catabolic process (GO:0019317) | 3.29506698 |
| 56 | L-fucose metabolic process (GO:0042354) | 3.29506698 |
| 57 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.28198804 |
| 58 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.28198804 |
| 59 | RNA catabolic process (GO:0006401) | 3.24497854 |
| 60 | deoxyribonucleotide catabolic process (GO:0009264) | 3.19448563 |
| 61 | catecholamine transport (GO:0051937) | 3.18280674 |
| 62 | cellular component biogenesis (GO:0044085) | 3.11016794 |
| 63 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.03795288 |
| 64 | organic cation transport (GO:0015695) | 3.02068709 |
| 65 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.00629517 |
| 66 | meiosis I (GO:0007127) | 2.98847526 |
| 67 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.98326103 |
| 68 | rRNA processing (GO:0006364) | 2.98186937 |
| 69 | transmission of nerve impulse (GO:0019226) | 2.97184989 |
| 70 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.94732054 |
| 71 | regulation of activation of Janus kinase activity (GO:0010533) | 2.94331134 |
| 72 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.91660942 |
| 73 | positive regulation of cell fate commitment (GO:0010455) | 2.91461855 |
| 74 | positive regulation of B cell mediated immunity (GO:0002714) | 2.89471595 |
| 75 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.89471595 |
| 76 | deoxyribose phosphate catabolic process (GO:0046386) | 2.88595390 |
| 77 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.87937367 |
| 78 | UMP metabolic process (GO:0046049) | 2.87937367 |
| 79 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.87937367 |
| 80 | UMP biosynthetic process (GO:0006222) | 2.87937367 |
| 81 | positive regulation of icosanoid secretion (GO:0032305) | 2.86294218 |
| 82 | rRNA metabolic process (GO:0016072) | 2.85835325 |
| 83 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.84478755 |
| 84 | leukotriene biosynthetic process (GO:0019370) | 2.82985428 |
| 85 | protein complex biogenesis (GO:0070271) | 2.79499825 |
| 86 | positive regulation of fatty acid transport (GO:2000193) | 2.79106060 |
| 87 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.78826152 |
| 88 | lymphocyte migration (GO:0072676) | 2.78350081 |
| 89 | GTP biosynthetic process (GO:0006183) | 2.77334446 |
| 90 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.75412732 |
| 91 | valine metabolic process (GO:0006573) | 2.74873356 |
| 92 | positive regulation of immunoglobulin production (GO:0002639) | 2.74048415 |
| 93 | arginine catabolic process (GO:0006527) | 2.72678056 |
| 94 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.70911632 |
| 95 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.70044437 |
| 96 | ATP biosynthetic process (GO:0006754) | 2.68883375 |
| 97 | heart trabecula morphogenesis (GO:0061384) | 2.68035205 |
| 98 | branched-chain amino acid catabolic process (GO:0009083) | 2.66038944 |
| 99 | protein neddylation (GO:0045116) | 2.64433776 |
| 100 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.64398363 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.34432604 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.21408358 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.12890630 |
| 4 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 3.03263271 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.81183556 |
| 6 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.64493162 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.61038843 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.34517799 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.31707654 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.30707978 |
| 11 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.16508661 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.15568610 |
| 13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.14731399 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.14420201 |
| 15 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.10130477 |
| 16 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.03927786 |
| 17 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.99027017 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.90677624 |
| 19 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.90017721 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.89056841 |
| 21 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.86322995 |
| 22 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.67260705 |
| 23 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.67252998 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.65975742 |
| 25 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60438084 |
| 26 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.57192172 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.56580349 |
| 28 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.55585847 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.54761805 |
| 30 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.52161735 |
| 31 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.46844555 |
| 32 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.46837832 |
| 33 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.45781648 |
| 34 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.45516587 |
| 35 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.43686406 |
| 36 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.43003531 |
| 37 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.42268622 |
| 38 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.42084700 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.38867378 |
| 40 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.35815164 |
| 41 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35346895 |
| 42 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.31400231 |
| 43 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.31059170 |
| 44 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.30707051 |
| 45 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.28952195 |
| 46 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.26318468 |
| 47 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.25862222 |
| 48 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.25344144 |
| 49 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.25336356 |
| 50 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25179681 |
| 51 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25179681 |
| 52 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25142345 |
| 53 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.22528807 |
| 54 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.22363832 |
| 55 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.21961520 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.20545433 |
| 57 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20489472 |
| 58 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.16846046 |
| 59 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.16786499 |
| 60 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.15549394 |
| 61 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.15443670 |
| 62 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15271810 |
| 63 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.15188610 |
| 64 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.14574036 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12381041 |
| 66 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12381041 |
| 67 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.11057612 |
| 68 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.10423428 |
| 69 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.09884974 |
| 70 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.09399740 |
| 71 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08632319 |
| 72 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08000000 |
| 73 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.07843515 |
| 74 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.07642152 |
| 75 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.07627779 |
| 76 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.06787715 |
| 77 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.06753660 |
| 78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.06245085 |
| 79 | SA1_27219007_Chip-Seq_Bcells_Human | 1.05879352 |
| 80 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.05240262 |
| 81 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.05237298 |
| 82 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05234548 |
| 83 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.04943879 |
| 84 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.04908250 |
| 85 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.03574695 |
| 86 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03214432 |
| 87 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.02678935 |
| 88 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.01887903 |
| 89 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00026024 |
| 90 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.99147869 |
| 91 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.98752957 |
| 92 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.98666960 |
| 93 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.98666960 |
| 94 | GATA3_26560356_Chip-Seq_TH2_Human | 0.98189095 |
| 95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.97992506 |
| 96 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.97982644 |
| 97 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.97206107 |
| 98 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95524092 |
| 99 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.95070434 |
| 100 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.94819451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.05277914 |
| 2 | MP0002132_abnormal_respiratory_system | 3.99107956 |
| 3 | MP0003646_muscle_fatigue | 3.80905903 |
| 4 | MP0006082_CNS_inflammation | 3.72219821 |
| 5 | MP0005671_abnormal_response_to | 3.28547751 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.77812707 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.72353308 |
| 8 | MP0002736_abnormal_nociception_after | 2.30234309 |
| 9 | MP0001529_abnormal_vocalization | 2.20182894 |
| 10 | MP0002638_abnormal_pupillary_reflex | 2.13058425 |
| 11 | MP0004885_abnormal_endolymph | 1.99909646 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 1.98751829 |
| 13 | MP0001986_abnormal_taste_sensitivity | 1.93299316 |
| 14 | MP0001968_abnormal_touch/_nociception | 1.93243001 |
| 15 | MP0002837_dystrophic_cardiac_calcinosis | 1.87155220 |
| 16 | MP0002160_abnormal_reproductive_system | 1.81610661 |
| 17 | MP0003195_calcinosis | 1.78226814 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 1.71640491 |
| 19 | MP0001663_abnormal_digestive_system | 1.69433208 |
| 20 | MP0009785_altered_susceptibility_to | 1.66365823 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 1.64500024 |
| 22 | MP0010155_abnormal_intestine_physiology | 1.61516209 |
| 23 | MP0001800_abnormal_humoral_immune | 1.60707792 |
| 24 | MP0005389_reproductive_system_phenotype | 1.59001678 |
| 25 | MP0001873_stomach_inflammation | 1.58625748 |
| 26 | MP0003252_abnormal_bile_duct | 1.56868013 |
| 27 | MP0005387_immune_system_phenotype | 1.55214354 |
| 28 | MP0001790_abnormal_immune_system | 1.55214354 |
| 29 | MP0005360_urolithiasis | 1.53865579 |
| 30 | MP0004142_abnormal_muscle_tone | 1.53665406 |
| 31 | MP0000858_altered_metastatic_potential | 1.43254740 |
| 32 | MP0002138_abnormal_hepatobiliary_system | 1.36792174 |
| 33 | MP0008872_abnormal_physiological_respon | 1.33484816 |
| 34 | MP0005377_hearing/vestibular/ear_phenot | 1.33456086 |
| 35 | MP0003878_abnormal_ear_physiology | 1.33456086 |
| 36 | MP0001348_abnormal_lacrimal_gland | 1.31998319 |
| 37 | MP0003718_maternal_effect | 1.31251855 |
| 38 | MP0008789_abnormal_olfactory_epithelium | 1.27973772 |
| 39 | MP0008775_abnormal_heart_ventricle | 1.27878752 |
| 40 | MP0005408_hypopigmentation | 1.26821279 |
| 41 | MP0005000_abnormal_immune_tolerance | 1.25257094 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.19574557 |
| 43 | MP0003011_delayed_dark_adaptation | 1.18763803 |
| 44 | MP0005167_abnormal_blood-brain_barrier | 1.17657512 |
| 45 | MP0002723_abnormal_immune_serum | 1.15970812 |
| 46 | MP0005381_digestive/alimentary_phenotyp | 1.15312248 |
| 47 | MP0001919_abnormal_reproductive_system | 1.14137513 |
| 48 | MP0002102_abnormal_ear_morphology | 1.14039350 |
| 49 | MP0005645_abnormal_hypothalamus_physiol | 1.13677719 |
| 50 | MP0002163_abnormal_gland_morphology | 1.08439097 |
| 51 | MP0000049_abnormal_middle_ear | 1.06718319 |
| 52 | MP0000631_abnormal_neuroendocrine_gland | 1.06017188 |
| 53 | MP0002405_respiratory_system_inflammati | 1.05580776 |
| 54 | MP0005646_abnormal_pituitary_gland | 1.05136724 |
| 55 | MP0000685_abnormal_immune_system | 1.03727221 |
| 56 | MP0009745_abnormal_behavioral_response | 1.03367380 |
| 57 | MP0004036_abnormal_muscle_relaxation | 1.00998576 |
| 58 | MP0004742_abnormal_vestibular_system | 1.00282315 |
| 59 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94961072 |
| 60 | MP0002210_abnormal_sex_determination | 0.94563333 |
| 61 | MP0002452_abnormal_antigen_presenting | 0.94496781 |
| 62 | MP0001905_abnormal_dopamine_level | 0.93814679 |
| 63 | MP0004782_abnormal_surfactant_physiolog | 0.93205486 |
| 64 | MP0005025_abnormal_response_to | 0.92963637 |
| 65 | MP0002272_abnormal_nervous_system | 0.92495985 |
| 66 | MP0001984_abnormal_olfaction | 0.92064583 |
| 67 | MP0009333_abnormal_splenocyte_physiolog | 0.91925666 |
| 68 | MP0002420_abnormal_adaptive_immunity | 0.89032577 |
| 69 | MP0008877_abnormal_DNA_methylation | 0.88950085 |
| 70 | MP0005253_abnormal_eye_physiology | 0.88135680 |
| 71 | MP0003879_abnormal_hair_cell | 0.87795583 |
| 72 | MP0001819_abnormal_immune_cell | 0.87743903 |
| 73 | MP0003119_abnormal_digestive_system | 0.87310815 |
| 74 | MP0004043_abnormal_pH_regulation | 0.86850095 |
| 75 | MP0002876_abnormal_thyroid_physiology | 0.86751642 |
| 76 | MP0005499_abnormal_olfactory_system | 0.84321541 |
| 77 | MP0005394_taste/olfaction_phenotype | 0.84321541 |
| 78 | MP0009764_decreased_sensitivity_to | 0.82852296 |
| 79 | MP0001119_abnormal_female_reproductive | 0.81537053 |
| 80 | MP0001970_abnormal_pain_threshold | 0.80532974 |
| 81 | MP0004147_increased_porphyrin_level | 0.79243086 |
| 82 | MP0003137_abnormal_impulse_conducting | 0.79236907 |
| 83 | MP0003936_abnormal_reproductive_system | 0.79148805 |
| 84 | MP0001845_abnormal_inflammatory_respons | 0.76299794 |
| 85 | MP0003136_yellow_coat_color | 0.76295735 |
| 86 | MP0008469_abnormal_protein_level | 0.75675121 |
| 87 | MP0005410_abnormal_fertilization | 0.75659707 |
| 88 | MP0001727_abnormal_embryo_implantation | 0.75001118 |
| 89 | MP0002733_abnormal_thermal_nociception | 0.74097559 |
| 90 | MP0005195_abnormal_posterior_eye | 0.73533904 |
| 91 | MP0002184_abnormal_innervation | 0.73039222 |
| 92 | MP0009697_abnormal_copulation | 0.72241162 |
| 93 | MP0002735_abnormal_chemical_nociception | 0.69704193 |
| 94 | MP0005379_endocrine/exocrine_gland_phen | 0.67977212 |
| 95 | MP0009250_abnormal_appendicular_skeleto | 0.67424862 |
| 96 | MP0001485_abnormal_pinna_reflex | 0.67403378 |
| 97 | MP0002933_joint_inflammation | 0.66652667 |
| 98 | MP0000490_abnormal_crypts_of | 0.66561987 |
| 99 | MP0002277_abnormal_respiratory_mucosa | 0.66427618 |
| 100 | MP0002095_abnormal_skin_pigmentation | 0.66360890 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nasal polyposis (HP:0100582) | 8.52488983 |
| 2 | Abnormality of the nasal mucosa (HP:0000433) | 7.01548055 |
| 3 | Chronic otitis media (HP:0000389) | 6.07206216 |
| 4 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.22219204 |
| 5 | Chronic sinusitis (HP:0011109) | 4.14799690 |
| 6 | Macrocytic anemia (HP:0001972) | 4.13772131 |
| 7 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.87254708 |
| 8 | Recurrent bronchitis (HP:0002837) | 3.76256238 |
| 9 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.55146768 |
| 10 | Hypothermia (HP:0002045) | 3.43397005 |
| 11 | Pallor (HP:0000980) | 3.14091775 |
| 12 | Zonular cataract (HP:0010920) | 3.05413897 |
| 13 | Congenital stationary night blindness (HP:0007642) | 2.83537733 |
| 14 | Acanthocytosis (HP:0001927) | 2.82322466 |
| 15 | Conjugated hyperbilirubinemia (HP:0002908) | 2.79117224 |
| 16 | Parakeratosis (HP:0001036) | 2.78354458 |
| 17 | Colon cancer (HP:0003003) | 2.77655530 |
| 18 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.77189822 |
| 19 | Lipid accumulation in hepatocytes (HP:0006561) | 2.73135663 |
| 20 | Decreased central vision (HP:0007663) | 2.72425542 |
| 21 | Poikilocytosis (HP:0004447) | 2.72405261 |
| 22 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.72321379 |
| 23 | Dyskinesia (HP:0100660) | 2.72319754 |
| 24 | Agitation (HP:0000713) | 2.68945340 |
| 25 | Pendular nystagmus (HP:0012043) | 2.66790337 |
| 26 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.54010300 |
| 27 | Abnormality of alanine metabolism (HP:0010916) | 2.54010300 |
| 28 | Hyperalaninemia (HP:0003348) | 2.54010300 |
| 29 | Acute necrotizing encephalopathy (HP:0006965) | 2.49639826 |
| 30 | Attenuation of retinal blood vessels (HP:0007843) | 2.49524406 |
| 31 | 3-Methylglutaconic aciduria (HP:0003535) | 2.48992208 |
| 32 | Bronchitis (HP:0012387) | 2.48896411 |
| 33 | Hemiplegia (HP:0002301) | 2.43752596 |
| 34 | Cerebral hypomyelination (HP:0006808) | 2.42858651 |
| 35 | Megaloblastic anemia (HP:0001889) | 2.40633269 |
| 36 | Mitochondrial inheritance (HP:0001427) | 2.33830106 |
| 37 | Septo-optic dysplasia (HP:0100842) | 2.25276974 |
| 38 | IgG deficiency (HP:0004315) | 2.23352375 |
| 39 | Hypoproteinemia (HP:0003075) | 2.23107650 |
| 40 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.22546076 |
| 41 | Congenital sensorineural hearing impairment (HP:0008527) | 2.22105389 |
| 42 | Abnormality of midbrain morphology (HP:0002418) | 2.19905515 |
| 43 | Molar tooth sign on MRI (HP:0002419) | 2.19905515 |
| 44 | Absent thumb (HP:0009777) | 2.18346302 |
| 45 | Abnormality of T cell physiology (HP:0011840) | 2.16986186 |
| 46 | Personality changes (HP:0000751) | 2.16891605 |
| 47 | Thrombocytosis (HP:0001894) | 2.15981502 |
| 48 | Increased CSF lactate (HP:0002490) | 2.11425241 |
| 49 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.11197132 |
| 50 | Reticulocytopenia (HP:0001896) | 2.11118784 |
| 51 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.10605611 |
| 52 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.10605611 |
| 53 | Global brain atrophy (HP:0002283) | 2.08171305 |
| 54 | Degeneration of anterior horn cells (HP:0002398) | 2.08129594 |
| 55 | Abnormality of the anterior horn cell (HP:0006802) | 2.08129594 |
| 56 | Progressive macrocephaly (HP:0004481) | 2.07570099 |
| 57 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.07367328 |
| 58 | Exertional dyspnea (HP:0002875) | 2.06863998 |
| 59 | Type 2 muscle fiber atrophy (HP:0003554) | 2.05000500 |
| 60 | Medial flaring of the eyebrow (HP:0010747) | 2.04668554 |
| 61 | Abnormality of T cells (HP:0002843) | 2.03917110 |
| 62 | Acute encephalopathy (HP:0006846) | 2.02569111 |
| 63 | Myositis (HP:0100614) | 2.00546861 |
| 64 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.99430121 |
| 65 | Increased hepatocellular lipid droplets (HP:0006565) | 1.99173475 |
| 66 | Abnormal number of erythroid precursors (HP:0012131) | 1.98426221 |
| 67 | Delayed CNS myelination (HP:0002188) | 1.97704563 |
| 68 | Increased corneal curvature (HP:0100692) | 1.97149814 |
| 69 | Keratoconus (HP:0000563) | 1.97149814 |
| 70 | Stomatitis (HP:0010280) | 1.96998478 |
| 71 | Erythroderma (HP:0001019) | 1.96871849 |
| 72 | Congenital, generalized hypertrichosis (HP:0004540) | 1.95452000 |
| 73 | Hepatocellular necrosis (HP:0001404) | 1.92449188 |
| 74 | Abnormal number of incisors (HP:0011064) | 1.92422720 |
| 75 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.91026425 |
| 76 | Neurodegeneration (HP:0002180) | 1.86622233 |
| 77 | Esophageal neoplasm (HP:0100751) | 1.84381277 |
| 78 | Neoplasm of head and neck (HP:0012288) | 1.84381277 |
| 79 | Methylmalonic acidemia (HP:0002912) | 1.82109203 |
| 80 | Constricted visual fields (HP:0001133) | 1.81689119 |
| 81 | Muscle fiber atrophy (HP:0100295) | 1.80022371 |
| 82 | Abnormal hemoglobin (HP:0011902) | 1.75388497 |
| 83 | Restlessness (HP:0000711) | 1.73989355 |
| 84 | Clumsiness (HP:0002312) | 1.71358435 |
| 85 | Renal Fanconi syndrome (HP:0001994) | 1.69183649 |
| 86 | Optic nerve hypoplasia (HP:0000609) | 1.67403327 |
| 87 | Nephronophthisis (HP:0000090) | 1.67155467 |
| 88 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.66006485 |
| 89 | Stenosis of the external auditory canal (HP:0000402) | 1.65308594 |
| 90 | Emphysema (HP:0002097) | 1.64318975 |
| 91 | Stomach cancer (HP:0012126) | 1.63530546 |
| 92 | Methylmalonic aciduria (HP:0012120) | 1.63458268 |
| 93 | Lethargy (HP:0001254) | 1.62705651 |
| 94 | Bronchiectasis (HP:0002110) | 1.62478759 |
| 95 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.62368140 |
| 96 | Optic disc pallor (HP:0000543) | 1.62217806 |
| 97 | Agammaglobulinemia (HP:0004432) | 1.62208328 |
| 98 | Nephrogenic diabetes insipidus (HP:0009806) | 1.62196797 |
| 99 | Palmoplantar hyperkeratosis (HP:0000972) | 1.60206241 |
| 100 | Short femoral neck (HP:0100864) | 1.60006212 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K13 | 5.81313341 |
| 2 | TLK1 | 4.36502261 |
| 3 | ITK | 3.16300562 |
| 4 | ADRBK2 | 2.96985928 |
| 5 | ERN1 | 2.94058539 |
| 6 | WNK4 | 2.59214723 |
| 7 | TXK | 2.50199953 |
| 8 | NME2 | 2.48542172 |
| 9 | TAOK3 | 2.39052301 |
| 10 | STK39 | 2.07880449 |
| 11 | MAP3K9 | 2.07858298 |
| 12 | ARAF | 1.78461120 |
| 13 | MAP2K2 | 1.69866279 |
| 14 | TIE1 | 1.62350467 |
| 15 | PTK2B | 1.53306166 |
| 16 | FRK | 1.52528512 |
| 17 | ZAP70 | 1.51377786 |
| 18 | GRK1 | 1.43047851 |
| 19 | WNK3 | 1.40481593 |
| 20 | BMPR2 | 1.40144464 |
| 21 | STK16 | 1.36169053 |
| 22 | BCKDK | 1.31514666 |
| 23 | MAP3K12 | 1.31287519 |
| 24 | INSRR | 1.23054021 |
| 25 | MAPK13 | 1.22628231 |
| 26 | BRAF | 1.21363737 |
| 27 | ADRBK1 | 1.18026962 |
| 28 | ILK | 1.12078004 |
| 29 | DYRK2 | 1.10287968 |
| 30 | MAP4K1 | 1.06731270 |
| 31 | PIM1 | 1.04932678 |
| 32 | FES | 1.04701567 |
| 33 | PDK2 | 1.02870779 |
| 34 | SYK | 1.02587889 |
| 35 | ZAK | 1.02143932 |
| 36 | LRRK2 | 0.95299129 |
| 37 | IKBKB | 0.94166779 |
| 38 | TBK1 | 0.92830225 |
| 39 | MAP4K2 | 0.89859057 |
| 40 | PRKG2 | 0.88099819 |
| 41 | BMPR1B | 0.87844406 |
| 42 | MOS | 0.86195941 |
| 43 | BTK | 0.85158930 |
| 44 | TEC | 0.84806305 |
| 45 | MAP3K8 | 0.79175676 |
| 46 | PRKCG | 0.78843643 |
| 47 | IKBKE | 0.78784756 |
| 48 | PIK3CA | 0.77755038 |
| 49 | ACVR1B | 0.76837842 |
| 50 | PRKCQ | 0.75710639 |
| 51 | OBSCN | 0.74354925 |
| 52 | VRK1 | 0.74284641 |
| 53 | PKN1 | 0.74236636 |
| 54 | RPS6KA5 | 0.74139637 |
| 55 | MYLK | 0.73776024 |
| 56 | PLK4 | 0.73366376 |
| 57 | NUAK1 | 0.73262328 |
| 58 | MUSK | 0.71753259 |
| 59 | MAP3K14 | 0.69774506 |
| 60 | PINK1 | 0.66781180 |
| 61 | PRKCZ | 0.65927549 |
| 62 | PASK | 0.65807106 |
| 63 | OXSR1 | 0.65413510 |
| 64 | GSK3A | 0.65294700 |
| 65 | MAP2K6 | 0.63513061 |
| 66 | CHEK2 | 0.62984648 |
| 67 | NEK1 | 0.60189868 |
| 68 | LCK | 0.59116929 |
| 69 | KDR | 0.59038676 |
| 70 | STK11 | 0.56837869 |
| 71 | PRKACA | 0.55401059 |
| 72 | MAP3K7 | 0.55177354 |
| 73 | CSNK1A1 | 0.54711419 |
| 74 | CSNK2A1 | 0.52992689 |
| 75 | WNK1 | 0.52352766 |
| 76 | HCK | 0.52262318 |
| 77 | GRK7 | 0.51320380 |
| 78 | PHKG2 | 0.50142898 |
| 79 | PHKG1 | 0.50142898 |
| 80 | MAPK7 | 0.49795240 |
| 81 | MAP2K1 | 0.49474288 |
| 82 | RPS6KA6 | 0.46215878 |
| 83 | PRKCA | 0.46188980 |
| 84 | CAMK2A | 0.43089745 |
| 85 | CSNK2A2 | 0.42715338 |
| 86 | CDK19 | 0.42082358 |
| 87 | JAK3 | 0.42033101 |
| 88 | EPHA2 | 0.40518567 |
| 89 | LYN | 0.40454237 |
| 90 | CAMK2D | 0.39867910 |
| 91 | IGF1R | 0.39804447 |
| 92 | RPS6KB2 | 0.39740296 |
| 93 | TGFBR1 | 0.38952961 |
| 94 | PRKACG | 0.38086002 |
| 95 | DAPK3 | 0.37375935 |
| 96 | CSNK1G3 | 0.35343995 |
| 97 | CDK4 | 0.34476907 |
| 98 | PRKCE | 0.33943794 |
| 99 | CAMK2G | 0.33875455 |
| 100 | AURKB | 0.31685390 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.51686576 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.49114103 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.82950531 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.52220969 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.49425407 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.37064706 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.35852698 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.25454318 |
| 9 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.17528213 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.17490848 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.14213817 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.01842368 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.88419172 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.85543870 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.80060194 |
| 16 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.67822228 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64404828 |
| 18 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.58237841 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.56252359 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.50169204 |
| 21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.47643590 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.44498089 |
| 23 | RNA polymerase_Homo sapiens_hsa03020 | 1.43703498 |
| 24 | Proteasome_Homo sapiens_hsa03050 | 1.43249303 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.38986087 |
| 26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.38822931 |
| 27 | Sulfur relay system_Homo sapiens_hsa04122 | 1.36945302 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35806941 |
| 29 | Olfactory transduction_Homo sapiens_hsa04740 | 1.35381444 |
| 30 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.33346079 |
| 31 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.31283489 |
| 32 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.29173480 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.28812020 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.27758445 |
| 35 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.27755155 |
| 36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.24508048 |
| 37 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.23924373 |
| 38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.23250878 |
| 39 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.18258944 |
| 40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.15203159 |
| 41 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.12169597 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 1.12150543 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10684034 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.07833430 |
| 45 | Nicotine addiction_Homo sapiens_hsa05033 | 1.06401820 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.05431796 |
| 47 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.03043351 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.93995342 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.91508176 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.91156231 |
| 51 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.85448378 |
| 52 | Malaria_Homo sapiens_hsa05144 | 0.83877131 |
| 53 | Protein export_Homo sapiens_hsa03060 | 0.81939831 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.81526094 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.81079028 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76624797 |
| 57 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.76016715 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70986243 |
| 59 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.69507616 |
| 60 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.68020658 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67597363 |
| 62 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.63414112 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.61505578 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.61400935 |
| 65 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.61392096 |
| 66 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.61250337 |
| 67 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.59261306 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.58908129 |
| 69 | Morphine addiction_Homo sapiens_hsa05032 | 0.58497646 |
| 70 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.57889153 |
| 71 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53911166 |
| 72 | Purine metabolism_Homo sapiens_hsa00230 | 0.53664570 |
| 73 | Taste transduction_Homo sapiens_hsa04742 | 0.53171470 |
| 74 | Leishmaniasis_Homo sapiens_hsa05140 | 0.52148867 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51599284 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45149774 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.42809857 |
| 78 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.41542996 |
| 79 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.39702298 |
| 80 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.36497951 |
| 81 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.34465551 |
| 82 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32724967 |
| 83 | RNA transport_Homo sapiens_hsa03013 | 0.32006000 |
| 84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31351911 |
| 85 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29083678 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25762312 |
| 87 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.24910363 |
| 88 | GABAergic synapse_Homo sapiens_hsa04727 | 0.24412094 |
| 89 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.22437149 |
| 90 | DNA replication_Homo sapiens_hsa03030 | 0.21780017 |
| 91 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.21558598 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.21385853 |
| 93 | Insulin secretion_Homo sapiens_hsa04911 | 0.15144277 |
| 94 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.14090409 |
| 95 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.12698598 |
| 96 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.12696350 |
| 97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.12252394 |
| 98 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.09524216 |
| 99 | Mineral absorption_Homo sapiens_hsa04978 | 0.08875132 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.08800671 |

