

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 7.15010763 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 7.12123583 |
| 3 | translational termination (GO:0006415) | 6.85124600 |
| 4 | maturation of SSU-rRNA (GO:0030490) | 6.71452022 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 6.60494208 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.04999837 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 6.04999837 |
| 8 | translational elongation (GO:0006414) | 5.89563908 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.84389532 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 5.77613873 |
| 11 | protein targeting to ER (GO:0045047) | 5.74107800 |
| 12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.51742361 |
| 13 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.48047861 |
| 14 | protein localization to endoplasmic reticulum (GO:0070972) | 5.43816372 |
| 15 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.19523289 |
| 16 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.19523289 |
| 17 | NADH dehydrogenase complex assembly (GO:0010257) | 5.19523289 |
| 18 | cellular protein complex disassembly (GO:0043624) | 5.17340460 |
| 19 | viral life cycle (GO:0019058) | 5.12094925 |
| 20 | protein complex biogenesis (GO:0070271) | 5.04050037 |
| 21 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.87270421 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.81208064 |
| 23 | translational initiation (GO:0006413) | 4.56567004 |
| 24 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.56412122 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.44404552 |
| 26 | protein complex disassembly (GO:0043241) | 4.40941637 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 4.31096547 |
| 28 | macromolecular complex disassembly (GO:0032984) | 4.25581825 |
| 29 | behavioral response to nicotine (GO:0035095) | 4.20613010 |
| 30 | protein polyglutamylation (GO:0018095) | 4.17519292 |
| 31 | respiratory electron transport chain (GO:0022904) | 4.16382319 |
| 32 | electron transport chain (GO:0022900) | 4.11949969 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 4.04166142 |
| 34 | translation (GO:0006412) | 3.89961501 |
| 35 | ATP biosynthetic process (GO:0006754) | 3.88414874 |
| 36 | protein targeting to membrane (GO:0006612) | 3.80447482 |
| 37 | cellular component biogenesis (GO:0044085) | 3.72088075 |
| 38 | protein neddylation (GO:0045116) | 3.63801525 |
| 39 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.62667248 |
| 40 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.60030445 |
| 41 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.58299047 |
| 42 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.50242954 |
| 43 | cardiovascular system development (GO:0072358) | 3.47957992 |
| 44 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.47648017 |
| 45 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.47437275 |
| 46 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.47437275 |
| 47 | DNA deamination (GO:0045006) | 3.40197796 |
| 48 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.37129115 |
| 49 | termination of RNA polymerase III transcription (GO:0006386) | 3.37129115 |
| 50 | mRNA catabolic process (GO:0006402) | 3.30335708 |
| 51 | positive regulation of T cell apoptotic process (GO:0070234) | 3.23572167 |
| 52 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.18589054 |
| 53 | cell proliferation in forebrain (GO:0021846) | 3.17581821 |
| 54 | somite development (GO:0061053) | 3.12593404 |
| 55 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.07659681 |
| 56 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.06345068 |
| 57 | hydrogen ion transmembrane transport (GO:1902600) | 3.00135562 |
| 58 | rRNA processing (GO:0006364) | 2.98637892 |
| 59 | RNA catabolic process (GO:0006401) | 2.97539784 |
| 60 | rRNA metabolic process (GO:0016072) | 2.94098472 |
| 61 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.94007694 |
| 62 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.94007694 |
| 63 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.92751396 |
| 64 | ubiquinone biosynthetic process (GO:0006744) | 2.87885252 |
| 65 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.86784495 |
| 66 | kinetochore assembly (GO:0051382) | 2.86401951 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.85704132 |
| 68 | resolution of meiotic recombination intermediates (GO:0000712) | 2.84779061 |
| 69 | hypothalamus development (GO:0021854) | 2.84270362 |
| 70 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.84011354 |
| 71 | GTP biosynthetic process (GO:0006183) | 2.81133101 |
| 72 | peptidyl-histidine modification (GO:0018202) | 2.78633458 |
| 73 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.78369446 |
| 74 | proton transport (GO:0015992) | 2.75017260 |
| 75 | positive regulation of growth hormone secretion (GO:0060124) | 2.70237914 |
| 76 | respiratory chain complex IV assembly (GO:0008535) | 2.70112534 |
| 77 | pseudouridine synthesis (GO:0001522) | 2.70104797 |
| 78 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.68865689 |
| 79 | protein targeting to mitochondrion (GO:0006626) | 2.68421205 |
| 80 | hydrogen transport (GO:0006818) | 2.67299806 |
| 81 | establishment of protein localization to membrane (GO:0090150) | 2.66745176 |
| 82 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.66732215 |
| 83 | replication fork processing (GO:0031297) | 2.65685433 |
| 84 | protein targeting (GO:0006605) | 2.64903143 |
| 85 | establishment of protein localization to mitochondrion (GO:0072655) | 2.64313992 |
| 86 | regulation of mitochondrial translation (GO:0070129) | 2.62574898 |
| 87 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.60740446 |
| 88 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.59618463 |
| 89 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.59618463 |
| 90 | tRNA processing (GO:0008033) | 2.58206835 |
| 91 | neuron fate determination (GO:0048664) | 2.58026439 |
| 92 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.57248364 |
| 93 | positive regulation of fatty acid transport (GO:2000193) | 2.55884307 |
| 94 | positive regulation of prostaglandin secretion (GO:0032308) | 2.53720417 |
| 95 | cytochrome complex assembly (GO:0017004) | 2.53513785 |
| 96 | protein localization to mitochondrion (GO:0070585) | 2.52485481 |
| 97 | positive regulation of icosanoid secretion (GO:0032305) | 2.51734729 |
| 98 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.50741218 |
| 99 | establishment of protein localization to organelle (GO:0072594) | 2.49557943 |
| 100 | microtubule severing (GO:0051013) | 2.48835799 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.86999806 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.67896038 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.95557323 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94239713 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.33700252 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.25050503 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.05741983 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.03497401 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.02985582 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.60738914 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.41596018 |
| 12 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.31904329 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.09433675 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.05262827 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.02538249 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.01324922 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.98911890 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.93111409 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.87483446 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.86370330 |
| 21 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.85301211 |
| 22 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.85074120 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.83609335 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.82508781 |
| 25 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.78107740 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.75909646 |
| 27 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.74493477 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.70220654 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.69765708 |
| 30 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.67587439 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.66303650 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.66119876 |
| 33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.62546708 |
| 34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.55251264 |
| 35 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.55203216 |
| 36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.51819317 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.49327345 |
| 38 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.48525681 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.48268022 |
| 40 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.46356621 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.46083787 |
| 42 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.43977022 |
| 43 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.41923099 |
| 44 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.41428318 |
| 45 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.40060935 |
| 46 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.38206355 |
| 47 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.37554940 |
| 48 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.34179135 |
| 49 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.33641833 |
| 50 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31124633 |
| 51 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.30680171 |
| 52 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.29925562 |
| 53 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.25820549 |
| 54 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.25573934 |
| 55 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.25205747 |
| 56 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.24629223 |
| 57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.24253096 |
| 58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.22941352 |
| 59 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.22422323 |
| 60 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19969238 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.12422642 |
| 62 | ERA_21632823_ChIP-Seq_H3396_Human | 1.11613697 |
| 63 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.10748283 |
| 64 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.09930032 |
| 65 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.09417835 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08624417 |
| 67 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07732807 |
| 68 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.07026730 |
| 69 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.06839020 |
| 70 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.06735714 |
| 71 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05666694 |
| 72 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.05611093 |
| 73 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.05401303 |
| 74 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.03447868 |
| 75 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.02820941 |
| 76 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.01591183 |
| 77 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00569306 |
| 78 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.99402695 |
| 79 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.98809481 |
| 80 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98774798 |
| 81 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.98389951 |
| 82 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.98331593 |
| 83 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.95678033 |
| 84 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.95052472 |
| 85 | AR_20517297_ChIP-Seq_VCAP_Human | 0.92865247 |
| 86 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.92728340 |
| 87 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.91999121 |
| 88 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91466466 |
| 89 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.91402244 |
| 90 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.90056782 |
| 91 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89087008 |
| 92 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.88676173 |
| 93 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.88526349 |
| 94 | EWS_26573619_Chip-Seq_HEK293_Human | 0.88267993 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87916253 |
| 96 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.87479352 |
| 97 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.87389784 |
| 98 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.87080964 |
| 99 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.86885453 |
| 100 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.86591313 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.79494149 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.92576620 |
| 3 | MP0002163_abnormal_gland_morphology | 3.67351675 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.19043179 |
| 5 | MP0001986_abnormal_taste_sensitivity | 3.05991406 |
| 6 | MP0003787_abnormal_imprinting | 3.05933405 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.76202171 |
| 8 | MP0002234_abnormal_pharynx_morphology | 2.69990630 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.45501868 |
| 10 | MP0004142_abnormal_muscle_tone | 2.29720360 |
| 11 | MP0008789_abnormal_olfactory_epithelium | 2.19445399 |
| 12 | MP0006276_abnormal_autonomic_nervous | 2.00226279 |
| 13 | MP0003122_maternal_imprinting | 1.99903915 |
| 14 | MP0005379_endocrine/exocrine_gland_phen | 1.97969919 |
| 15 | MP0003121_genomic_imprinting | 1.94697289 |
| 16 | MP0001293_anophthalmia | 1.93692236 |
| 17 | MP0004147_increased_porphyrin_level | 1.88661393 |
| 18 | MP0002653_abnormal_ependyma_morphology | 1.78552332 |
| 19 | MP0002837_dystrophic_cardiac_calcinosis | 1.78248983 |
| 20 | MP0005394_taste/olfaction_phenotype | 1.77429107 |
| 21 | MP0005499_abnormal_olfactory_system | 1.77429107 |
| 22 | MP0003880_abnormal_central_pattern | 1.76446623 |
| 23 | MP0002102_abnormal_ear_morphology | 1.67936858 |
| 24 | MP0002876_abnormal_thyroid_physiology | 1.67078822 |
| 25 | MP0003123_paternal_imprinting | 1.64951781 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.64572842 |
| 27 | MP0002938_white_spotting | 1.64248629 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.63284782 |
| 29 | MP0001905_abnormal_dopamine_level | 1.63079257 |
| 30 | MP0004885_abnormal_endolymph | 1.62479367 |
| 31 | MP0003283_abnormal_digestive_organ | 1.57963517 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.52441851 |
| 33 | MP0000778_abnormal_nervous_system | 1.50511916 |
| 34 | MP0000049_abnormal_middle_ear | 1.47740260 |
| 35 | MP0003186_abnormal_redox_activity | 1.46433556 |
| 36 | MP0002272_abnormal_nervous_system | 1.43724012 |
| 37 | MP0002160_abnormal_reproductive_system | 1.41461251 |
| 38 | MP0009745_abnormal_behavioral_response | 1.41389855 |
| 39 | MP0002736_abnormal_nociception_after | 1.40811292 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.39246627 |
| 41 | MP0001529_abnormal_vocalization | 1.34210526 |
| 42 | MP0009046_muscle_twitch | 1.33374621 |
| 43 | MP0008872_abnormal_physiological_respon | 1.33254551 |
| 44 | MP0005646_abnormal_pituitary_gland | 1.27448269 |
| 45 | MP0005551_abnormal_eye_electrophysiolog | 1.27228054 |
| 46 | MP0000631_abnormal_neuroendocrine_gland | 1.24723583 |
| 47 | MP0001984_abnormal_olfaction | 1.20677143 |
| 48 | MP0006072_abnormal_retinal_apoptosis | 1.18918001 |
| 49 | MP0010030_abnormal_orbit_morphology | 1.18792404 |
| 50 | MP0002557_abnormal_social/conspecific_i | 1.18736861 |
| 51 | MP0005389_reproductive_system_phenotype | 1.17273082 |
| 52 | MP0002733_abnormal_thermal_nociception | 1.17180639 |
| 53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.15844009 |
| 54 | MP0005084_abnormal_gallbladder_morpholo | 1.14628202 |
| 55 | MP0002184_abnormal_innervation | 1.11837887 |
| 56 | MP0001970_abnormal_pain_threshold | 1.11721902 |
| 57 | MP0005174_abnormal_tail_pigmentation | 1.10784318 |
| 58 | MP0008775_abnormal_heart_ventricle | 1.06103439 |
| 59 | MP0000955_abnormal_spinal_cord | 1.04166542 |
| 60 | MP0001486_abnormal_startle_reflex | 1.03114648 |
| 61 | MP0001188_hyperpigmentation | 1.01938396 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.00376554 |
| 63 | MP0001485_abnormal_pinna_reflex | 1.00375865 |
| 64 | MP0008058_abnormal_DNA_repair | 0.99637869 |
| 65 | MP0001919_abnormal_reproductive_system | 0.98574060 |
| 66 | MP0002752_abnormal_somatic_nervous | 0.98509792 |
| 67 | MP0002572_abnormal_emotion/affect_behav | 0.98072669 |
| 68 | MP0000372_irregular_coat_pigmentation | 0.97145530 |
| 69 | MP0002822_catalepsy | 0.96175558 |
| 70 | MP0002063_abnormal_learning/memory/cond | 0.95371485 |
| 71 | MP0003718_maternal_effect | 0.94311837 |
| 72 | MP0002734_abnormal_mechanical_nocicepti | 0.93572191 |
| 73 | MP0002210_abnormal_sex_determination | 0.93103249 |
| 74 | MP0001440_abnormal_grooming_behavior | 0.92412793 |
| 75 | MP0005195_abnormal_posterior_eye | 0.90405720 |
| 76 | MP0004742_abnormal_vestibular_system | 0.88391177 |
| 77 | MP0003635_abnormal_synaptic_transmissio | 0.87863530 |
| 78 | MP0006036_abnormal_mitochondrial_physio | 0.86779315 |
| 79 | MP0002138_abnormal_hepatobiliary_system | 0.86699838 |
| 80 | MP0003786_premature_aging | 0.84807091 |
| 81 | MP0005377_hearing/vestibular/ear_phenot | 0.84797569 |
| 82 | MP0003878_abnormal_ear_physiology | 0.84797569 |
| 83 | MP0002064_seizures | 0.84758781 |
| 84 | MP0003937_abnormal_limbs/digits/tail_de | 0.83455648 |
| 85 | MP0003315_abnormal_perineum_morphology | 0.82223895 |
| 86 | MP0003011_delayed_dark_adaptation | 0.80947520 |
| 87 | MP0006035_abnormal_mitochondrial_morpho | 0.80932631 |
| 88 | MP0002233_abnormal_nose_morphology | 0.80665477 |
| 89 | MP0002638_abnormal_pupillary_reflex | 0.79095556 |
| 90 | MP0002067_abnormal_sensory_capabilities | 0.78640818 |
| 91 | MP0005075_abnormal_melanosome_morpholog | 0.77933666 |
| 92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77618892 |
| 93 | MP0003646_muscle_fatigue | 0.76520647 |
| 94 | MP0000427_abnormal_hair_cycle | 0.74647696 |
| 95 | MP0000026_abnormal_inner_ear | 0.74636591 |
| 96 | MP0004924_abnormal_behavior | 0.73158138 |
| 97 | MP0005386_behavior/neurological_phenoty | 0.73158138 |
| 98 | MP0001502_abnormal_circadian_rhythm | 0.72958888 |
| 99 | MP0002882_abnormal_neuron_morphology | 0.70669277 |
| 100 | MP0000647_abnormal_sebaceous_gland | 0.70258275 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.15049267 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.83078744 |
| 3 | Reticulocytopenia (HP:0001896) | 4.69612973 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.57261546 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.56062927 |
| 6 | Acute encephalopathy (HP:0006846) | 4.40616213 |
| 7 | Progressive macrocephaly (HP:0004481) | 4.22224770 |
| 8 | Increased CSF lactate (HP:0002490) | 4.02101299 |
| 9 | Abnormal number of erythroid precursors (HP:0012131) | 3.91727529 |
| 10 | Colon cancer (HP:0003003) | 3.90997410 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.81203810 |
| 12 | Macrocytic anemia (HP:0001972) | 3.72441359 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.68928477 |
| 14 | Molar tooth sign on MRI (HP:0002419) | 3.68928477 |
| 15 | Increased hepatocellular lipid droplets (HP:0006565) | 3.53745318 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.48327752 |
| 17 | Hepatic necrosis (HP:0002605) | 3.38383749 |
| 18 | Pancreatic fibrosis (HP:0100732) | 3.34359689 |
| 19 | Cerebral edema (HP:0002181) | 3.24822410 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 3.23822886 |
| 21 | Medial flaring of the eyebrow (HP:0010747) | 3.01757224 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 2.95777981 |
| 23 | Pancreatic cysts (HP:0001737) | 2.92462398 |
| 24 | True hermaphroditism (HP:0010459) | 2.75870953 |
| 25 | Nephronophthisis (HP:0000090) | 2.69019454 |
| 26 | Absent/shortened dynein arms (HP:0200106) | 2.61288091 |
| 27 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.61288091 |
| 28 | Pallor (HP:0000980) | 2.61205789 |
| 29 | Sclerocornea (HP:0000647) | 2.60787780 |
| 30 | Lactic acidosis (HP:0003128) | 2.55304426 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 2.53885779 |
| 32 | Optic disc pallor (HP:0000543) | 2.53248156 |
| 33 | Increased serum lactate (HP:0002151) | 2.53215357 |
| 34 | Absent thumb (HP:0009777) | 2.52490692 |
| 35 | Limb dystonia (HP:0002451) | 2.42380319 |
| 36 | Congenital malformation of the right heart (HP:0011723) | 2.40241951 |
| 37 | Double outlet right ventricle (HP:0001719) | 2.40241951 |
| 38 | Exertional dyspnea (HP:0002875) | 2.39234167 |
| 39 | Respiratory failure (HP:0002878) | 2.36786843 |
| 40 | Congenital stationary night blindness (HP:0007642) | 2.34998264 |
| 41 | Type II lissencephaly (HP:0007260) | 2.32394512 |
| 42 | Pendular nystagmus (HP:0012043) | 2.28505650 |
| 43 | Abnormality of renal resorption (HP:0011038) | 2.28413183 |
| 44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.27368270 |
| 45 | Abnormal number of incisors (HP:0011064) | 2.26927938 |
| 46 | Leukodystrophy (HP:0002415) | 2.26442792 |
| 47 | Increased muscle lipid content (HP:0009058) | 2.23663743 |
| 48 | Septo-optic dysplasia (HP:0100842) | 2.19805614 |
| 49 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.18188093 |
| 50 | Maternal diabetes (HP:0009800) | 2.18103599 |
| 51 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.17827032 |
| 52 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.17827032 |
| 53 | Rib fusion (HP:0000902) | 2.15008508 |
| 54 | Abnormality of DNA repair (HP:0003254) | 2.14210746 |
| 55 | Tubular atrophy (HP:0000092) | 2.14050088 |
| 56 | Exercise intolerance (HP:0003546) | 2.11280227 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.11093814 |
| 58 | Abnormality of the renal medulla (HP:0100957) | 2.10673838 |
| 59 | Neoplasm of the adrenal cortex (HP:0100641) | 2.09265030 |
| 60 | Anophthalmia (HP:0000528) | 2.08343589 |
| 61 | Polyphagia (HP:0002591) | 2.07492001 |
| 62 | Cystic liver disease (HP:0006706) | 2.05765297 |
| 63 | Abnormality of urine glucose concentration (HP:0011016) | 2.04807156 |
| 64 | Glycosuria (HP:0003076) | 2.04807156 |
| 65 | Hypothermia (HP:0002045) | 2.04335760 |
| 66 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.03202254 |
| 67 | Stenosis of the external auditory canal (HP:0000402) | 1.99656615 |
| 68 | Anencephaly (HP:0002323) | 1.97878212 |
| 69 | Pachygyria (HP:0001302) | 1.95796042 |
| 70 | Abnormal drinking behavior (HP:0030082) | 1.94625011 |
| 71 | Polydipsia (HP:0001959) | 1.94625011 |
| 72 | Gait imbalance (HP:0002141) | 1.93762730 |
| 73 | Depressed nasal ridge (HP:0000457) | 1.92055243 |
| 74 | Lethargy (HP:0001254) | 1.90964877 |
| 75 | Hyperglycinemia (HP:0002154) | 1.90252900 |
| 76 | Hypoplasia of the radius (HP:0002984) | 1.89688272 |
| 77 | Abolished electroretinogram (ERG) (HP:0000550) | 1.89437183 |
| 78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.83812438 |
| 79 | Growth hormone deficiency (HP:0000824) | 1.82703606 |
| 80 | Hyperphosphaturia (HP:0003109) | 1.82306122 |
| 81 | Abnormal hemoglobin (HP:0011902) | 1.81598084 |
| 82 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.81382554 |
| 83 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.81382554 |
| 84 | Hyperglycinuria (HP:0003108) | 1.79811646 |
| 85 | Congenital primary aphakia (HP:0007707) | 1.79459333 |
| 86 | Type 2 muscle fiber atrophy (HP:0003554) | 1.78093495 |
| 87 | Narrow forehead (HP:0000341) | 1.77851317 |
| 88 | Muscle fiber atrophy (HP:0100295) | 1.77698365 |
| 89 | Broad-based gait (HP:0002136) | 1.75984748 |
| 90 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.75125208 |
| 91 | Agitation (HP:0000713) | 1.74594144 |
| 92 | Lissencephaly (HP:0001339) | 1.74342767 |
| 93 | Abnormal ciliary motility (HP:0012262) | 1.72801929 |
| 94 | Renal cortical cysts (HP:0000803) | 1.72115466 |
| 95 | X-linked dominant inheritance (HP:0001423) | 1.72104334 |
| 96 | Occipital encephalocele (HP:0002085) | 1.71169977 |
| 97 | Male pseudohermaphroditism (HP:0000037) | 1.70987633 |
| 98 | Entropion (HP:0000621) | 1.70553108 |
| 99 | Nephrogenic diabetes insipidus (HP:0009806) | 1.70283336 |
| 100 | Optic nerve coloboma (HP:0000588) | 1.69580270 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.40406937 |
| 2 | NUAK1 | 3.48759855 |
| 3 | TAF1 | 3.12835581 |
| 4 | TXK | 2.84978650 |
| 5 | TLK1 | 2.78774834 |
| 6 | ZAK | 2.71550814 |
| 7 | DYRK2 | 2.66740881 |
| 8 | VRK1 | 2.09993707 |
| 9 | MAP4K2 | 2.07405238 |
| 10 | STK16 | 1.99984369 |
| 11 | GRK1 | 1.93238289 |
| 12 | WNK4 | 1.91554650 |
| 13 | ADRBK2 | 1.77803984 |
| 14 | BCKDK | 1.73418364 |
| 15 | CSNK1G2 | 1.70718482 |
| 16 | TIE1 | 1.70371571 |
| 17 | MAPK13 | 1.69707236 |
| 18 | PRKD3 | 1.67026240 |
| 19 | SMG1 | 1.64200285 |
| 20 | CSNK1G3 | 1.60599568 |
| 21 | MAP3K9 | 1.48998387 |
| 22 | MAP3K11 | 1.42365302 |
| 23 | NME2 | 1.39602725 |
| 24 | STK39 | 1.39531133 |
| 25 | PHKG2 | 1.38824329 |
| 26 | PHKG1 | 1.38824329 |
| 27 | PINK1 | 1.37390636 |
| 28 | CDC7 | 1.33317503 |
| 29 | CDK19 | 1.32575072 |
| 30 | CSNK1G1 | 1.31871184 |
| 31 | MAP2K2 | 1.27550075 |
| 32 | CSNK1A1L | 1.26053820 |
| 33 | DAPK3 | 1.20821688 |
| 34 | WNK3 | 1.16216300 |
| 35 | MAPKAPK5 | 1.11359832 |
| 36 | OXSR1 | 1.01620712 |
| 37 | PIK3CA | 1.01220054 |
| 38 | MARK1 | 1.01064461 |
| 39 | EPHB2 | 0.99551877 |
| 40 | MINK1 | 0.99337743 |
| 41 | GRK5 | 0.99285752 |
| 42 | IKBKB | 0.94775971 |
| 43 | BMPR1B | 0.93417835 |
| 44 | FRK | 0.87068658 |
| 45 | AURKA | 0.87006380 |
| 46 | CASK | 0.84943579 |
| 47 | BUB1 | 0.84098550 |
| 48 | CAMK1 | 0.83467790 |
| 49 | IKBKE | 0.83242711 |
| 50 | NTRK2 | 0.81289261 |
| 51 | DYRK3 | 0.80730846 |
| 52 | CHEK2 | 0.80487675 |
| 53 | RPS6KA5 | 0.80220895 |
| 54 | KIT | 0.78813924 |
| 55 | LRRK2 | 0.78472749 |
| 56 | TAOK3 | 0.73054542 |
| 57 | PRKCG | 0.72129534 |
| 58 | LIMK1 | 0.71478362 |
| 59 | MKNK2 | 0.69869765 |
| 60 | TYRO3 | 0.67437325 |
| 61 | INSRR | 0.66142501 |
| 62 | PLK3 | 0.64991473 |
| 63 | CSNK1E | 0.64632854 |
| 64 | MAP4K1 | 0.63453349 |
| 65 | STK11 | 0.63244541 |
| 66 | ABL2 | 0.63079586 |
| 67 | CSNK2A2 | 0.62971912 |
| 68 | PRKCI | 0.60839097 |
| 69 | AURKB | 0.58896575 |
| 70 | MAP2K7 | 0.58514739 |
| 71 | CAMK1D | 0.58393543 |
| 72 | PRKCQ | 0.56733683 |
| 73 | EIF2AK2 | 0.56712722 |
| 74 | BRAF | 0.53275376 |
| 75 | PRKACA | 0.52603319 |
| 76 | CAMK4 | 0.51399047 |
| 77 | MAP3K12 | 0.50861044 |
| 78 | DYRK1A | 0.50615585 |
| 79 | MKNK1 | 0.49410492 |
| 80 | CSNK1A1 | 0.49192894 |
| 81 | PAK3 | 0.48305025 |
| 82 | PLK4 | 0.47984808 |
| 83 | ADRBK1 | 0.46789402 |
| 84 | CSNK2A1 | 0.44824956 |
| 85 | NEK1 | 0.44362057 |
| 86 | CAMKK2 | 0.44247593 |
| 87 | DAPK1 | 0.41678868 |
| 88 | PLK1 | 0.41242741 |
| 89 | RPS6KA6 | 0.40233902 |
| 90 | TEC | 0.40050229 |
| 91 | DAPK2 | 0.39539330 |
| 92 | PNCK | 0.39237821 |
| 93 | ATR | 0.38355561 |
| 94 | GRK6 | 0.37669944 |
| 95 | CAMK1G | 0.37412454 |
| 96 | ITK | 0.36743574 |
| 97 | PRKCH | 0.35209486 |
| 98 | OBSCN | 0.35036897 |
| 99 | PRKCZ | 0.34445059 |
| 100 | EPHA4 | 0.32114597 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.35683811 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.72790519 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.13622724 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.84363072 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.77966362 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.47691425 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.44662779 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.42254578 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.23503424 |
| 10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.12068270 |
| 11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.10270161 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 2.05943824 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 1.84341547 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.81559835 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.80438914 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.80209649 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.64488321 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.54434769 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.40863210 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.39530644 |
| 21 | Sulfur relay system_Homo sapiens_hsa04122 | 1.39387521 |
| 22 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.35879708 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26875378 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.24182335 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.22251185 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19309115 |
| 27 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.14412617 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.10148414 |
| 29 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.03756866 |
| 30 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.01916678 |
| 31 | Nicotine addiction_Homo sapiens_hsa05033 | 0.97403420 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.96623814 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.96174554 |
| 34 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.89765534 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89126775 |
| 36 | Spliceosome_Homo sapiens_hsa03040 | 0.87655215 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84907262 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 0.83728952 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.83711437 |
| 40 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.82532438 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 0.81221506 |
| 42 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.80636837 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.79627896 |
| 44 | Allograft rejection_Homo sapiens_hsa05330 | 0.78759234 |
| 45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.78119005 |
| 46 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.77347250 |
| 47 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.75589745 |
| 48 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.73120418 |
| 49 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72892347 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.72489179 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71313868 |
| 52 | DNA replication_Homo sapiens_hsa03030 | 0.70013802 |
| 53 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.69960715 |
| 54 | RNA transport_Homo sapiens_hsa03013 | 0.69862481 |
| 55 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69395171 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.67669766 |
| 57 | Mismatch repair_Homo sapiens_hsa03430 | 0.65890476 |
| 58 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.65751283 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65386840 |
| 60 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.65287489 |
| 61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64490625 |
| 62 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64342027 |
| 63 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.61026695 |
| 64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.60708396 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.60642843 |
| 66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59023076 |
| 67 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.56725626 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51602089 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.50274414 |
| 70 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.50188972 |
| 71 | Alcoholism_Homo sapiens_hsa05034 | 0.48749718 |
| 72 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.47134608 |
| 73 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.46826319 |
| 74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.46148998 |
| 75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45933709 |
| 76 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45714597 |
| 77 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.45708412 |
| 78 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.44536614 |
| 79 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.43831559 |
| 80 | Insulin secretion_Homo sapiens_hsa04911 | 0.43476850 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41869140 |
| 82 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.41745689 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.39523992 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39424763 |
| 85 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37815376 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36273244 |
| 87 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35747051 |
| 88 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.34219561 |
| 89 | Circadian entrainment_Homo sapiens_hsa04713 | 0.33813802 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.32680021 |
| 91 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32217689 |
| 92 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.31736945 |
| 93 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.31460079 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.31180517 |
| 95 | Cocaine addiction_Homo sapiens_hsa05030 | 0.31119184 |
| 96 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.29263909 |
| 97 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.27931378 |
| 98 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.27588693 |
| 99 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.26828070 |
| 100 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.25852309 |

