

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.46390544 |
| 2 | negative regulation of cell killing (GO:0031342) | 6.28873709 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.28873709 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 6.03100820 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 6.03100820 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.03100820 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.03100820 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.03100820 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 6.03100820 |
| 10 | neutrophil activation involved in immune response (GO:0002283) | 5.72563846 |
| 11 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.60203509 |
| 12 | macrophage activation involved in immune response (GO:0002281) | 5.00721130 |
| 13 | detection of other organism (GO:0098543) | 4.95503942 |
| 14 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.95220257 |
| 15 | immunoglobulin mediated immune response (GO:0016064) | 4.87986936 |
| 16 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.75572634 |
| 17 | regulation of gamma-delta T cell activation (GO:0046643) | 4.73497098 |
| 18 | negative regulation of interleukin-12 production (GO:0032695) | 4.66487892 |
| 19 | positive regulation of mast cell activation (GO:0033005) | 4.66123671 |
| 20 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.64301828 |
| 21 | detection of bacterium (GO:0016045) | 4.60499921 |
| 22 | response to peptidoglycan (GO:0032494) | 4.55486882 |
| 23 | microglial cell activation (GO:0001774) | 4.52330303 |
| 24 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.46568484 |
| 25 | regulation of mast cell degranulation (GO:0043304) | 4.13900016 |
| 26 | regulation of mast cell activation (GO:0033003) | 4.13289481 |
| 27 | cellular extravasation (GO:0045123) | 4.08348002 |
| 28 | response to host immune response (GO:0052572) | 4.07586617 |
| 29 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.07586617 |
| 30 | neutrophil activation (GO:0042119) | 4.05975520 |
| 31 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.99518208 |
| 32 | detection of external biotic stimulus (GO:0098581) | 3.99217149 |
| 33 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.95237341 |
| 34 | negative regulation of T cell mediated immunity (GO:0002710) | 3.94374879 |
| 35 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.93098502 |
| 36 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.90515726 |
| 37 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.90458935 |
| 38 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.86021127 |
| 39 | positive regulation of mast cell degranulation (GO:0043306) | 3.86013567 |
| 40 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.86013567 |
| 41 | detection of molecule of bacterial origin (GO:0032490) | 3.84642590 |
| 42 | B cell mediated immunity (GO:0019724) | 3.84617394 |
| 43 | myeloid cell activation involved in immune response (GO:0002275) | 3.83087087 |
| 44 | negative regulation of stress fiber assembly (GO:0051497) | 3.80870192 |
| 45 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.80532143 |
| 46 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.72710926 |
| 47 | response to host (GO:0075136) | 3.72710926 |
| 48 | response to host defenses (GO:0052200) | 3.72710926 |
| 49 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.69365968 |
| 50 | macrophage activation (GO:0042116) | 3.68535991 |
| 51 | respiratory burst (GO:0045730) | 3.66130341 |
| 52 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.64409252 |
| 53 | leukocyte aggregation (GO:0070486) | 3.64262006 |
| 54 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.64173996 |
| 55 | granulocyte activation (GO:0036230) | 3.62084965 |
| 56 | positive regulation of B cell differentiation (GO:0045579) | 3.59977613 |
| 57 | detection of biotic stimulus (GO:0009595) | 3.55574080 |
| 58 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.53473760 |
| 59 | interferon-gamma secretion (GO:0072643) | 3.44201911 |
| 60 | regulation of leukocyte degranulation (GO:0043300) | 3.43277391 |
| 61 | positive thymic T cell selection (GO:0045059) | 3.40992525 |
| 62 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.33612110 |
| 63 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.30881912 |
| 64 | neutrophil mediated immunity (GO:0002446) | 3.28074351 |
| 65 | B cell receptor signaling pathway (GO:0050853) | 3.27938263 |
| 66 | regulation of DNA methylation (GO:0044030) | 3.26943511 |
| 67 | negative T cell selection (GO:0043383) | 3.24066182 |
| 68 | cell wall macromolecule metabolic process (GO:0044036) | 3.23356295 |
| 69 | regulation of tolerance induction (GO:0002643) | 3.23251456 |
| 70 | positive regulation of interferon-alpha production (GO:0032727) | 3.21860212 |
| 71 | positive regulation of humoral immune response (GO:0002922) | 3.16477338 |
| 72 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.16341867 |
| 73 | regulation of B cell differentiation (GO:0045577) | 3.15529918 |
| 74 | activated T cell proliferation (GO:0050798) | 3.12693554 |
| 75 | leukocyte degranulation (GO:0043299) | 3.12478186 |
| 76 | regulation of T cell tolerance induction (GO:0002664) | 3.11984587 |
| 77 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.11510182 |
| 78 | negative thymic T cell selection (GO:0045060) | 3.08392507 |
| 79 | regulation of regulatory T cell differentiation (GO:0045589) | 3.04331072 |
| 80 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.02249793 |
| 81 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.02211690 |
| 82 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.00689426 |
| 83 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.99142165 |
| 84 | regulation of interferon-alpha production (GO:0032647) | 2.95133257 |
| 85 | interferon-gamma production (GO:0032609) | 2.94660776 |
| 86 | regulation of regulated secretory pathway (GO:1903305) | 2.93413820 |
| 87 | positive T cell selection (GO:0043368) | 2.93263014 |
| 88 | positive regulation of isotype switching (GO:0045830) | 2.92303982 |
| 89 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.91645847 |
| 90 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.90545276 |
| 91 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.89478386 |
| 92 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.87340398 |
| 93 | regulation of female gonad development (GO:2000194) | 2.86023104 |
| 94 | response to interleukin-15 (GO:0070672) | 2.85839144 |
| 95 | regulation of platelet aggregation (GO:0090330) | 2.83968151 |
| 96 | negative regulation of innate immune response (GO:0045824) | 2.82672605 |
| 97 | positive regulation of interleukin-17 production (GO:0032740) | 2.82502897 |
| 98 | negative regulation of alpha-beta T cell activation (GO:0046636) | 2.81694055 |
| 99 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.80889059 |
| 100 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.80889059 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.42390466 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.23556727 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.62460023 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.60958431 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.60529696 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.23911782 |
| 7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.23082286 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.06903870 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.06390560 |
| 10 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.96144996 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.89218370 |
| 12 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.81380710 |
| 13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.78503165 |
| 14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.46734463 |
| 15 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.45590003 |
| 16 | SPI1_23127762_ChIP-Seq_K562_Human | 2.43662377 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.41457399 |
| 18 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.36863750 |
| 19 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.33247404 |
| 20 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.32071819 |
| 21 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.26725849 |
| 22 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.22289708 |
| 23 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.22061659 |
| 24 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.06800740 |
| 25 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.01972128 |
| 26 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.96986790 |
| 27 | MYB_26560356_Chip-Seq_TH2_Human | 1.96717956 |
| 28 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.94720242 |
| 29 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.93875270 |
| 30 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.92349061 |
| 31 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.90270583 |
| 32 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.87130007 |
| 33 | MYB_26560356_Chip-Seq_TH1_Human | 1.85085818 |
| 34 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.80339233 |
| 35 | UTX_26944678_Chip-Seq_JUKART_Human | 1.78103590 |
| 36 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.76225132 |
| 37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.72741304 |
| 38 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.72157812 |
| 39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.70455088 |
| 40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.66922946 |
| 41 | MAF_26560356_Chip-Seq_TH1_Human | 1.63629991 |
| 42 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.60948878 |
| 43 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59599599 |
| 44 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.55879335 |
| 45 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.49524089 |
| 46 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.42300778 |
| 47 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41200070 |
| 48 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.39441455 |
| 49 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.37099670 |
| 50 | GATA3_26560356_Chip-Seq_TH2_Human | 1.35556686 |
| 51 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.35290076 |
| 52 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.34808548 |
| 53 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.32709705 |
| 54 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31452423 |
| 55 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.28424542 |
| 56 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.25843688 |
| 57 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.25843688 |
| 58 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.25843688 |
| 59 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.21754603 |
| 60 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.21222821 |
| 61 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.20367946 |
| 62 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.18153266 |
| 63 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15727917 |
| 64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.14148012 |
| 65 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.11370370 |
| 66 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11369828 |
| 67 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.09339544 |
| 68 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09098227 |
| 69 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.07208961 |
| 70 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.05472671 |
| 71 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.02577031 |
| 72 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.02316594 |
| 73 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02258374 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97791371 |
| 75 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.97538559 |
| 76 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.96388647 |
| 77 | MAF_26560356_Chip-Seq_TH2_Human | 0.95685100 |
| 78 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.95600326 |
| 79 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.95016493 |
| 80 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.94159091 |
| 81 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.92040008 |
| 82 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.92034631 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.92005617 |
| 84 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.91079969 |
| 85 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.88018323 |
| 86 | GATA2_19941826_ChIP-Seq_K562_Human | 0.86750280 |
| 87 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.86723660 |
| 88 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.81898130 |
| 89 | MYC_22102868_ChIP-Seq_BL_Human | 0.81816604 |
| 90 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.80866883 |
| 91 | GATA1_19941826_ChIP-Seq_K562_Human | 0.80268325 |
| 92 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.80018499 |
| 93 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79914834 |
| 94 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.79596598 |
| 95 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.79371087 |
| 96 | P300_27268052_Chip-Seq_Bcells_Human | 0.77599148 |
| 97 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77269505 |
| 98 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.77185996 |
| 99 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.76995102 |
| 100 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.76163953 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.46071606 |
| 2 | MP0003436_decreased_susceptibility_to | 4.09761398 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.98515878 |
| 4 | MP0005671_abnormal_response_to | 3.34468588 |
| 5 | MP0002419_abnormal_innate_immunity | 3.22404432 |
| 6 | MP0006082_CNS_inflammation | 3.16467962 |
| 7 | MP0000685_abnormal_immune_system | 2.90510648 |
| 8 | MP0001800_abnormal_humoral_immune | 2.76440143 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.74093493 |
| 10 | MP0005025_abnormal_response_to | 2.69117461 |
| 11 | MP0009785_altered_susceptibility_to | 2.68069436 |
| 12 | MP0003303_peritoneal_inflammation | 2.52331861 |
| 13 | MP0002452_abnormal_antigen_presenting | 2.52238673 |
| 14 | MP0001790_abnormal_immune_system | 2.51942821 |
| 15 | MP0005387_immune_system_phenotype | 2.51942821 |
| 16 | MP0002420_abnormal_adaptive_immunity | 2.50454839 |
| 17 | MP0002723_abnormal_immune_serum | 2.49670638 |
| 18 | MP0001819_abnormal_immune_cell | 2.46069027 |
| 19 | MP0005464_abnormal_platelet_physiology | 2.40782367 |
| 20 | MP0002138_abnormal_hepatobiliary_system | 2.35024368 |
| 21 | MP0003646_muscle_fatigue | 2.18919115 |
| 22 | MP0002148_abnormal_hypersensitivity_rea | 2.16789687 |
| 23 | MP0003828_pulmonary_edema | 2.07587260 |
| 24 | MP0003183_abnormal_peptide_metabolism | 2.06414528 |
| 25 | MP0001533_abnormal_skeleton_physiology | 2.02488935 |
| 26 | MP0003191_abnormal_cellular_cholesterol | 2.01245570 |
| 27 | MP0002132_abnormal_respiratory_system | 1.94178271 |
| 28 | MP0004130_abnormal_muscle_cell | 1.86638003 |
| 29 | MP0000716_abnormal_immune_system | 1.76375879 |
| 30 | MP0002398_abnormal_bone_marrow | 1.73468096 |
| 31 | MP0008260_abnormal_autophagy | 1.73232034 |
| 32 | MP0005646_abnormal_pituitary_gland | 1.71759602 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.68972864 |
| 34 | MP0003879_abnormal_hair_cell | 1.67414011 |
| 35 | MP0002405_respiratory_system_inflammati | 1.60883691 |
| 36 | MP0001845_abnormal_inflammatory_respons | 1.58107962 |
| 37 | MP0003172_abnormal_lysosome_physiology | 1.57754542 |
| 38 | MP0000689_abnormal_spleen_morphology | 1.55738370 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.54253084 |
| 40 | MP0001853_heart_inflammation | 1.48159324 |
| 41 | MP0001986_abnormal_taste_sensitivity | 1.46594830 |
| 42 | MP0010155_abnormal_intestine_physiology | 1.43568666 |
| 43 | MP0000465_gastrointestinal_hemorrhage | 1.40711092 |
| 44 | MP0004381_abnormal_hair_follicle | 1.39918726 |
| 45 | MP0003718_maternal_effect | 1.36751655 |
| 46 | MP0002722_abnormal_immune_system | 1.35635585 |
| 47 | MP0005310_abnormal_salivary_gland | 1.33734084 |
| 48 | MP0003763_abnormal_thymus_physiology | 1.33368584 |
| 49 | MP0002429_abnormal_blood_cell | 1.32172168 |
| 50 | MP0003300_gastrointestinal_ulcer | 1.23406503 |
| 51 | MP0008469_abnormal_protein_level | 1.22458760 |
| 52 | MP0002998_abnormal_bone_remodeling | 1.21128143 |
| 53 | MP0008877_abnormal_DNA_methylation | 1.17248123 |
| 54 | MP0003866_abnormal_defecation | 1.12293758 |
| 55 | MP0000703_abnormal_thymus_morphology | 1.12229924 |
| 56 | MP0002166_altered_tumor_susceptibility | 1.11756290 |
| 57 | MP0004185_abnormal_adipocyte_glucose | 1.10919581 |
| 58 | MP0005360_urolithiasis | 1.10493658 |
| 59 | MP0002837_dystrophic_cardiac_calcinosis | 1.09256139 |
| 60 | MP0006292_abnormal_olfactory_placode | 1.08108518 |
| 61 | MP0004883_abnormal_blood_vessel | 1.07764595 |
| 62 | MP0004947_skin_inflammation | 1.07648682 |
| 63 | MP0005058_abnormal_lysosome_morphology | 1.05895827 |
| 64 | MP0000858_altered_metastatic_potential | 1.04339656 |
| 65 | MP0009764_decreased_sensitivity_to | 1.03396341 |
| 66 | MP0003075_altered_response_to | 0.99124185 |
| 67 | MP0005397_hematopoietic_system_phenotyp | 0.96873272 |
| 68 | MP0001545_abnormal_hematopoietic_system | 0.96873272 |
| 69 | MP0000343_altered_response_to | 0.95740275 |
| 70 | MP0003690_abnormal_glial_cell | 0.94986413 |
| 71 | MP0008789_abnormal_olfactory_epithelium | 0.93706605 |
| 72 | MP0005647_abnormal_sex_gland | 0.91996536 |
| 73 | MP0005075_abnormal_melanosome_morpholog | 0.91422876 |
| 74 | MP0008004_abnormal_stomach_pH | 0.89625199 |
| 75 | MP0005390_skeleton_phenotype | 0.88027817 |
| 76 | MP0002396_abnormal_hematopoietic_system | 0.86447915 |
| 77 | MP0001851_eye_inflammation | 0.86217882 |
| 78 | MP0000015_abnormal_ear_pigmentation | 0.83773798 |
| 79 | MP0005166_decreased_susceptibility_to | 0.81978042 |
| 80 | MP0009278_abnormal_bone_marrow | 0.75439201 |
| 81 | MP0001663_abnormal_digestive_system | 0.74978267 |
| 82 | MP0009053_abnormal_anal_canal | 0.74063002 |
| 83 | MP0003448_altered_tumor_morphology | 0.72929001 |
| 84 | MP0003806_abnormal_nucleotide_metabolis | 0.72888067 |
| 85 | MP0010234_abnormal_vibrissa_follicle | 0.71833911 |
| 86 | MP0009763_increased_sensitivity_to | 0.71405611 |
| 87 | MP0002006_tumorigenesis | 0.65818607 |
| 88 | MP0005164_abnormal_response_to | 0.65318059 |
| 89 | MP0004885_abnormal_endolymph | 0.62294064 |
| 90 | MP0009765_abnormal_xenobiotic_induced | 0.61673043 |
| 91 | MP0001764_abnormal_homeostasis | 0.61306263 |
| 92 | MP0000604_amyloidosis | 0.61022215 |
| 93 | MP0005410_abnormal_fertilization | 0.61016463 |
| 94 | MP0005083_abnormal_biliary_tract | 0.60713884 |
| 95 | MP0005394_taste/olfaction_phenotype | 0.60129349 |
| 96 | MP0005499_abnormal_olfactory_system | 0.60129349 |
| 97 | MP0000470_abnormal_stomach_morphology | 0.58717109 |
| 98 | MP0010678_abnormal_skin_adnexa | 0.57952447 |
| 99 | MP0004142_abnormal_muscle_tone | 0.52067610 |
| 100 | MP0001915_intracranial_hemorrhage | 0.51720498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.02192672 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.96605504 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.89933771 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.83752941 |
| 5 | Myositis (HP:0100614) | 5.20193324 |
| 6 | Orchitis (HP:0100796) | 4.77200794 |
| 7 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.75881482 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 4.75131898 |
| 9 | Optic neuritis (HP:0100653) | 4.75131898 |
| 10 | Stomatitis (HP:0010280) | 4.55670610 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.41675976 |
| 12 | Recurrent fungal infections (HP:0002841) | 4.06966566 |
| 13 | Recurrent skin infections (HP:0001581) | 3.96069159 |
| 14 | Recurrent cutaneous fungal infections (HP:0011370) | 3.75058167 |
| 15 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.75058167 |
| 16 | Obstructive lung disease (HP:0006536) | 3.53397150 |
| 17 | Chronic obstructive pulmonary disease (HP:0006510) | 3.53397150 |
| 18 | Spontaneous hematomas (HP:0007420) | 3.53287611 |
| 19 | Keratoconjunctivitis (HP:0001096) | 3.47060436 |
| 20 | Encephalitis (HP:0002383) | 3.46838053 |
| 21 | Mediastinal lymphadenopathy (HP:0100721) | 3.45740242 |
| 22 | Meningitis (HP:0001287) | 3.42356282 |
| 23 | Keratoconjunctivitis sicca (HP:0001097) | 3.35081367 |
| 24 | Gastrointestinal infarctions (HP:0005244) | 3.28906000 |
| 25 | Prolonged bleeding time (HP:0003010) | 3.28155494 |
| 26 | Abnormality of glycolipid metabolism (HP:0010969) | 3.11070311 |
| 27 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.11070311 |
| 28 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.11070311 |
| 29 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.07495423 |
| 30 | Gingivitis (HP:0000230) | 3.05681941 |
| 31 | Urticaria (HP:0001025) | 2.96508586 |
| 32 | Chest pain (HP:0100749) | 2.91583719 |
| 33 | Vasculitis (HP:0002633) | 2.89781497 |
| 34 | Gingival bleeding (HP:0000225) | 2.84852798 |
| 35 | Pulmonary infiltrates (HP:0002113) | 2.79589839 |
| 36 | Hemoptysis (HP:0002105) | 2.79060206 |
| 37 | Arterial thrombosis (HP:0004420) | 2.75895757 |
| 38 | Episodic fever (HP:0001954) | 2.72631505 |
| 39 | Leukocytosis (HP:0001974) | 2.70247542 |
| 40 | T lymphocytopenia (HP:0005403) | 2.68815894 |
| 41 | Pustule (HP:0200039) | 2.67357473 |
| 42 | Hypochromic microcytic anemia (HP:0004840) | 2.65190617 |
| 43 | Recurrent viral infections (HP:0004429) | 2.59997623 |
| 44 | Amyloidosis (HP:0011034) | 2.57542543 |
| 45 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.56256244 |
| 46 | Epistaxis (HP:0000421) | 2.52014360 |
| 47 | Increased IgE level (HP:0003212) | 2.51529349 |
| 48 | Abnormality of T cell number (HP:0011839) | 2.48042953 |
| 49 | Panhypogammaglobulinemia (HP:0003139) | 2.45849770 |
| 50 | Pulmonary embolism (HP:0002204) | 2.44559266 |
| 51 | Increased cerebral lipofuscin (HP:0011813) | 2.41661310 |
| 52 | Loss of speech (HP:0002371) | 2.37830401 |
| 53 | Anorexia (HP:0002039) | 2.34094185 |
| 54 | Malnutrition (HP:0004395) | 2.31484931 |
| 55 | Osteomyelitis (HP:0002754) | 2.31115638 |
| 56 | Vertigo (HP:0002321) | 2.30059366 |
| 57 | Increased IgM level (HP:0003496) | 2.29263999 |
| 58 | Hypochromic anemia (HP:0001931) | 2.26395682 |
| 59 | Hematochezia (HP:0002573) | 2.22675110 |
| 60 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.22456153 |
| 61 | Abnormality of T cells (HP:0002843) | 2.19756295 |
| 62 | Hemiplegia (HP:0002301) | 2.15992430 |
| 63 | Keratitis (HP:0000491) | 2.13679452 |
| 64 | Inflammation of the large intestine (HP:0002037) | 2.13337096 |
| 65 | Abnormality of the columella (HP:0009929) | 2.12727382 |
| 66 | Cellulitis (HP:0100658) | 2.12669755 |
| 67 | Petechiae (HP:0000967) | 2.12068677 |
| 68 | Increased serum ferritin (HP:0003281) | 2.11575681 |
| 69 | Purpura (HP:0000979) | 2.10058502 |
| 70 | Gastrointestinal inflammation (HP:0004386) | 2.09645401 |
| 71 | Agitation (HP:0000713) | 2.08271658 |
| 72 | Peritonitis (HP:0002586) | 2.05575575 |
| 73 | Chronic otitis media (HP:0000389) | 2.00768134 |
| 74 | Granulocytopenia (HP:0001913) | 2.00058797 |
| 75 | Gangrene (HP:0100758) | 1.97387350 |
| 76 | Microcytic anemia (HP:0001935) | 1.97009624 |
| 77 | Dysostosis multiplex (HP:0000943) | 1.95199622 |
| 78 | Eosinophilia (HP:0001880) | 1.94842186 |
| 79 | Amaurosis fugax (HP:0100576) | 1.92956789 |
| 80 | Abnormality of iron homeostasis (HP:0011031) | 1.89961127 |
| 81 | Abnormality of the pleura (HP:0002103) | 1.89375552 |
| 82 | Thrombocytosis (HP:0001894) | 1.88095786 |
| 83 | Sepsis (HP:0100806) | 1.85475137 |
| 84 | Porencephaly (HP:0002132) | 1.84198279 |
| 85 | Polyneuropathy (HP:0001271) | 1.82172345 |
| 86 | Premature loss of primary teeth (HP:0006323) | 1.80835881 |
| 87 | Toxemia of pregnancy (HP:0100603) | 1.79852262 |
| 88 | Lymphopenia (HP:0001888) | 1.78385825 |
| 89 | Abnormality of T cell physiology (HP:0011840) | 1.77880672 |
| 90 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.77493405 |
| 91 | Ventricular fibrillation (HP:0001663) | 1.77157419 |
| 92 | Memory impairment (HP:0002354) | 1.75961875 |
| 93 | Abnormality of the prostate (HP:0008775) | 1.75348890 |
| 94 | Disinhibition (HP:0000734) | 1.74409143 |
| 95 | Autoimmune thrombocytopenia (HP:0001973) | 1.71615383 |
| 96 | Glomerulopathy (HP:0100820) | 1.70774911 |
| 97 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.69764863 |
| 98 | Abnormal platelet volume (HP:0011876) | 1.68494245 |
| 99 | Cheilitis (HP:0100825) | 1.67971694 |
| 100 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.67951980 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.19933126 |
| 2 | MAP4K1 | 3.38913914 |
| 3 | BLK | 3.38913381 |
| 4 | MAP3K13 | 3.28521864 |
| 5 | TAOK3 | 2.92319417 |
| 6 | CSK | 2.75861416 |
| 7 | MAP3K9 | 2.66376642 |
| 8 | FES | 2.58488642 |
| 9 | TYK2 | 2.49064036 |
| 10 | TNK2 | 2.38207493 |
| 11 | MAP2K3 | 2.13759294 |
| 12 | BTK | 2.06108854 |
| 13 | ZAP70 | 1.92268192 |
| 14 | IRAK4 | 1.92211477 |
| 15 | ARAF | 1.83553578 |
| 16 | CSF1R | 1.82589337 |
| 17 | SYK | 1.71815811 |
| 18 | PRPF4B | 1.71387369 |
| 19 | TXK | 1.69926544 |
| 20 | TEC | 1.66783373 |
| 21 | HCK | 1.60947977 |
| 22 | FGR | 1.57978679 |
| 23 | GRK6 | 1.54927397 |
| 24 | MAP3K3 | 1.54281508 |
| 25 | LYN | 1.50485582 |
| 26 | KSR2 | 1.49910544 |
| 27 | KIT | 1.49025620 |
| 28 | ITK | 1.44545325 |
| 29 | JAK3 | 1.40349358 |
| 30 | MOS | 1.32470139 |
| 31 | EPHB1 | 1.30766461 |
| 32 | MARK3 | 1.28568124 |
| 33 | PDK1 | 1.24428262 |
| 34 | IKBKE | 1.22244243 |
| 35 | LCK | 1.19830421 |
| 36 | STK10 | 1.19710685 |
| 37 | MAP3K14 | 1.16219421 |
| 38 | ERN1 | 1.08147250 |
| 39 | MAP3K11 | 1.08106670 |
| 40 | JAK2 | 1.06507335 |
| 41 | TBK1 | 1.06452017 |
| 42 | CDK19 | 1.06261072 |
| 43 | YES1 | 1.02999639 |
| 44 | STK24 | 1.02707201 |
| 45 | MAP3K1 | 1.00452617 |
| 46 | IKBKB | 0.94035987 |
| 47 | MATK | 0.92214462 |
| 48 | TESK2 | 0.91321838 |
| 49 | TGFBR2 | 0.89555560 |
| 50 | BMPR2 | 0.86023942 |
| 51 | PDPK1 | 0.85600781 |
| 52 | PRKCQ | 0.83892471 |
| 53 | LRRK2 | 0.82407490 |
| 54 | RAF1 | 0.81973178 |
| 55 | JAK1 | 0.81630671 |
| 56 | NEK6 | 0.80168463 |
| 57 | PRKD2 | 0.77124597 |
| 58 | CAMKK1 | 0.73736275 |
| 59 | GRK7 | 0.71969354 |
| 60 | STK11 | 0.71842795 |
| 61 | PIK3CG | 0.71120798 |
| 62 | KDR | 0.70003793 |
| 63 | CAMKK2 | 0.69586581 |
| 64 | FYN | 0.67996793 |
| 65 | PIM1 | 0.66187551 |
| 66 | CDK9 | 0.64139283 |
| 67 | SIK3 | 0.61004070 |
| 68 | KSR1 | 0.58703026 |
| 69 | IRAK1 | 0.58512671 |
| 70 | MAP3K5 | 0.56232001 |
| 71 | PTK6 | 0.54948366 |
| 72 | TAOK1 | 0.54477007 |
| 73 | MAP3K7 | 0.51624333 |
| 74 | ABL1 | 0.50841783 |
| 75 | GRK1 | 0.49054052 |
| 76 | OXSR1 | 0.48994791 |
| 77 | MAPK7 | 0.48125453 |
| 78 | IRAK2 | 0.46624485 |
| 79 | PTK2B | 0.46372338 |
| 80 | MST4 | 0.43261780 |
| 81 | BRAF | 0.42986135 |
| 82 | MARK2 | 0.41722739 |
| 83 | DAPK2 | 0.41148153 |
| 84 | RPS6KA6 | 0.40748649 |
| 85 | RPS6KL1 | 0.37693059 |
| 86 | RPS6KC1 | 0.37693059 |
| 87 | PRKCZ | 0.36082888 |
| 88 | MELK | 0.35364016 |
| 89 | MAP2K4 | 0.35155366 |
| 90 | FGFR3 | 0.34032614 |
| 91 | PRKD1 | 0.33101361 |
| 92 | SGK3 | 0.32587807 |
| 93 | TAOK2 | 0.32463563 |
| 94 | NEK9 | 0.32376346 |
| 95 | MAPKAPK2 | 0.32229658 |
| 96 | FRK | 0.32072265 |
| 97 | MAP3K8 | 0.31999134 |
| 98 | ADRBK1 | 0.29787034 |
| 99 | MAPKAPK3 | 0.29172144 |
| 100 | PAK1 | 0.28821081 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.11373162 |
| 2 | Leishmaniasis_Homo sapiens_hsa05140 | 2.91206411 |
| 3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.76895078 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.56949066 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.53484929 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.42645204 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.12967225 |
| 8 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.12222094 |
| 9 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.11913533 |
| 10 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.06461052 |
| 11 | Tuberculosis_Homo sapiens_hsa05152 | 2.05452240 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.91237584 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.91003974 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.89394793 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.82043525 |
| 16 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.80415634 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.80378911 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.78989283 |
| 19 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.75723221 |
| 20 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.69965791 |
| 21 | Malaria_Homo sapiens_hsa05144 | 1.62341641 |
| 22 | Phagosome_Homo sapiens_hsa04145 | 1.59877874 |
| 23 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.56284435 |
| 24 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.51809994 |
| 25 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.51533443 |
| 26 | Other glycan degradation_Homo sapiens_hsa00511 | 1.47154574 |
| 27 | Measles_Homo sapiens_hsa05162 | 1.45747385 |
| 28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.38102981 |
| 29 | Viral myocarditis_Homo sapiens_hsa05416 | 1.37323390 |
| 30 | Legionellosis_Homo sapiens_hsa05134 | 1.27451201 |
| 31 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.27053823 |
| 32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.23187037 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.21234462 |
| 34 | Influenza A_Homo sapiens_hsa05164 | 1.19963555 |
| 35 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.17913639 |
| 36 | Platelet activation_Homo sapiens_hsa04611 | 1.11914796 |
| 37 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.11571580 |
| 38 | Shigellosis_Homo sapiens_hsa05131 | 1.08553329 |
| 39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.07992658 |
| 40 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.04629138 |
| 41 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99869433 |
| 42 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.97752796 |
| 43 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.95823463 |
| 44 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.94959789 |
| 45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.94873147 |
| 46 | Pertussis_Homo sapiens_hsa05133 | 0.93377753 |
| 47 | Lysosome_Homo sapiens_hsa04142 | 0.91313006 |
| 48 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.90909623 |
| 49 | Hepatitis B_Homo sapiens_hsa05161 | 0.88875723 |
| 50 | Salmonella infection_Homo sapiens_hsa05132 | 0.87894926 |
| 51 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.86744057 |
| 52 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.84044883 |
| 53 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.83213283 |
| 54 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.76992498 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.75972441 |
| 56 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.75787297 |
| 57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.73308735 |
| 58 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.71744879 |
| 59 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.71505875 |
| 60 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.69384447 |
| 61 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.69133594 |
| 62 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.66691791 |
| 63 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.66277774 |
| 64 | Phototransduction_Homo sapiens_hsa04744 | 0.64218110 |
| 65 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.64064601 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63583429 |
| 67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.62768510 |
| 68 | Endocytosis_Homo sapiens_hsa04144 | 0.62714754 |
| 69 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.60194469 |
| 70 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.59719206 |
| 71 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58373821 |
| 72 | Morphine addiction_Homo sapiens_hsa05032 | 0.57718024 |
| 73 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.56761616 |
| 74 | Hepatitis C_Homo sapiens_hsa05160 | 0.55849701 |
| 75 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.54136851 |
| 76 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.49493217 |
| 77 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.48582730 |
| 78 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.48544448 |
| 79 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.48427850 |
| 80 | Apoptosis_Homo sapiens_hsa04210 | 0.47741714 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.47494016 |
| 82 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.45908273 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.45713553 |
| 84 | Insulin resistance_Homo sapiens_hsa04931 | 0.45629676 |
| 85 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.45402402 |
| 86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44640391 |
| 87 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.43257028 |
| 88 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.42920139 |
| 89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.41744930 |
| 90 | HTLV-I infection_Homo sapiens_hsa05166 | 0.41265582 |
| 91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.41170111 |
| 92 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.41076968 |
| 93 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.40991207 |
| 94 | Amoebiasis_Homo sapiens_hsa05146 | 0.40784776 |
| 95 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.39579686 |
| 96 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.39422862 |
| 97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.38210785 |
| 98 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.37280951 |
| 99 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.36202800 |
| 100 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.35311347 |

