RPL7L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)4.86360753
2nucleobase biosynthetic process (GO:0046112)4.75620815
3maturation of SSU-rRNA (GO:0030490)4.74258027
4purine nucleobase biosynthetic process (GO:0009113)4.61543318
5DNA strand elongation involved in DNA replication (GO:0006271)4.45395050
6formation of translation preinitiation complex (GO:0001731)4.44116668
7regulation of translational fidelity (GO:0006450)4.31391488
8IMP biosynthetic process (GO:0006188)4.24289130
9DNA strand elongation (GO:0022616)4.23865341
10pore complex assembly (GO:0046931)4.20701325
11DNA replication initiation (GO:0006270)4.20629988
12telomere maintenance via semi-conservative replication (GO:0032201)4.15670126
13ribosome assembly (GO:0042255)4.14442419
14sister chromatid segregation (GO:0000819)4.10795408
15folic acid-containing compound biosynthetic process (GO:0009396)4.09810869
16ribosomal large subunit biogenesis (GO:0042273)4.07924358
17establishment of integrated proviral latency (GO:0075713)4.06534105
18mitotic metaphase plate congression (GO:0007080)3.99269239
19ribosome biogenesis (GO:0042254)3.98039982
20DNA unwinding involved in DNA replication (GO:0006268)3.96017926
21protein localization to kinetochore (GO:0034501)3.92658250
22DNA replication checkpoint (GO:0000076)3.92488038
23mitotic chromosome condensation (GO:0007076)3.89795514
24ribonucleoprotein complex biogenesis (GO:0022613)3.89297003
25viral transcription (GO:0019083)3.84638904
26translational termination (GO:0006415)3.80580977
27DNA replication-dependent nucleosome organization (GO:0034723)3.74971131
28DNA replication-dependent nucleosome assembly (GO:0006335)3.74971131
29mitotic nuclear envelope disassembly (GO:0007077)3.74876713
30telomere maintenance via recombination (GO:0000722)3.73340367
31ribosomal small subunit biogenesis (GO:0042274)3.72451465
32IMP metabolic process (GO:0046040)3.65936342
33translational initiation (GO:0006413)3.55697259
34mitotic recombination (GO:0006312)3.53323561
35translational elongation (GO:0006414)3.52925375
36rRNA processing (GO:0006364)3.51138801
37nuclear pore organization (GO:0006999)3.47008572
38membrane disassembly (GO:0030397)3.41828855
39nuclear envelope disassembly (GO:0051081)3.41828855
40spliceosomal snRNP assembly (GO:0000387)3.41645609
41CENP-A containing nucleosome assembly (GO:0034080)3.38783575
42rRNA metabolic process (GO:0016072)3.38160186
43DNA deamination (GO:0045006)3.38002995
44telomere maintenance via telomere lengthening (GO:0010833)3.37484086
45chromatin remodeling at centromere (GO:0031055)3.35945203
46metaphase plate congression (GO:0051310)3.34110451
47SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.33087384
48regulation of centriole replication (GO:0046599)3.32732280
49mitotic sister chromatid cohesion (GO:0007064)3.30659651
50rRNA modification (GO:0000154)3.29339195
51nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.28584085
52proteasome assembly (GO:0043248)3.24449855
53protein localization to chromosome, centromeric region (GO:0071459)3.23293682
54cotranslational protein targeting to membrane (GO:0006613)3.22767016
55protein targeting to ER (GO:0045047)3.22107033
56nucleotide-excision repair, DNA gap filling (GO:0006297)3.20700244
57maturation of 5.8S rRNA (GO:0000460)3.19832595
58folic acid metabolic process (GO:0046655)3.18366277
59negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.17456079
60amino acid activation (GO:0043038)3.17009796
61tRNA aminoacylation (GO:0043039)3.17009796
62tRNA aminoacylation for protein translation (GO:0006418)3.16954436
63regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16597620
64anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.16257386
65regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.12670768
66pseudouridine synthesis (GO:0001522)3.12482478
67positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.10366325
68regulation of spindle organization (GO:0090224)3.10344296
69regulation of mitochondrial translation (GO:0070129)3.09983660
70transcription-coupled nucleotide-excision repair (GO:0006283)3.09078804
71DNA replication-independent nucleosome organization (GO:0034724)3.06937988
72DNA replication-independent nucleosome assembly (GO:0006336)3.06937988
73regulation of centrosome cycle (GO:0046605)3.05177009
74establishment of protein localization to endoplasmic reticulum (GO:0072599)3.02991217
75heterochromatin organization (GO:0070828)3.02764030
76protein localization to endoplasmic reticulum (GO:0070972)3.02565504
77nuclear pore complex assembly (GO:0051292)3.01772096
78establishment of chromosome localization (GO:0051303)3.00656552
79attachment of spindle microtubules to kinetochore (GO:0008608)3.00161192
80viral life cycle (GO:0019058)2.99647291
81kinetochore organization (GO:0051383)2.98985824
82cellular protein complex disassembly (GO:0043624)2.98707834
83mitotic sister chromatid segregation (GO:0000070)2.95990912
84translation (GO:0006412)2.95502153
85regulation of translational termination (GO:0006449)2.94115422
86non-recombinational repair (GO:0000726)2.92143959
87double-strand break repair via nonhomologous end joining (GO:0006303)2.92143959
88termination of RNA polymerase I transcription (GO:0006363)2.91351537
89spliceosomal complex assembly (GO:0000245)2.91193531
90regulation of translational elongation (GO:0006448)2.90938086
91cellular component biogenesis (GO:0044085)2.90771240
92cell cycle G1/S phase transition (GO:0044843)2.90454879
93G1/S transition of mitotic cell cycle (GO:0000082)2.90454879
94establishment of viral latency (GO:0019043)2.90322165
95negative regulation of ligase activity (GO:0051352)2.88659081
96negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.88659081
97somatic hypermutation of immunoglobulin genes (GO:0016446)2.88557618
98somatic diversification of immune receptors via somatic mutation (GO:0002566)2.88557618
99transcription elongation from RNA polymerase III promoter (GO:0006385)2.87459226
100termination of RNA polymerase III transcription (GO:0006386)2.87459226
101regulation of DNA endoreduplication (GO:0032875)2.87294508
102regulation of mitotic spindle organization (GO:0060236)2.86505293
103transcription elongation from RNA polymerase I promoter (GO:0006362)2.86181396
104mitochondrial RNA metabolic process (GO:0000959)2.85968754
105transcription from RNA polymerase I promoter (GO:0006360)2.85444826
106DNA topological change (GO:0006265)2.83699858
107positive regulation of chromosome segregation (GO:0051984)2.81403952
108viral mRNA export from host cell nucleus (GO:0046784)2.79598969
109regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.78381911
110nucleobase-containing small molecule interconversion (GO:0015949)2.77743374
111DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.77079023
112DNA strand renaturation (GO:0000733)2.76471805
113DNA duplex unwinding (GO:0032508)2.76358719
114positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.75889708
115DNA geometric change (GO:0032392)2.75224631
116histone exchange (GO:0043486)2.74466659
117signal transduction involved in DNA integrity checkpoint (GO:0072401)2.74283467
118signal transduction involved in DNA damage checkpoint (GO:0072422)2.74283467
119signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.73711840
120signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.73711840
121signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.73711840
122spindle checkpoint (GO:0031577)2.73467030
123signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.73317411
124intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.73317411
125nuclear envelope organization (GO:0006998)2.72999518
126tetrahydrofolate metabolic process (GO:0046653)2.72456175
127negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.72119245
128nuclear-transcribed mRNA catabolic process (GO:0000956)2.72027355
129regulation of chromosome segregation (GO:0051983)2.71520082
130regulation of sister chromatid cohesion (GO:0007063)2.70391337
131tRNA methylation (GO:0030488)2.70271762
132chromosome segregation (GO:0007059)2.68817255
133protein complex localization (GO:0031503)2.67245160
134replication fork processing (GO:0031297)2.66704722
135regulation of centrosome duplication (GO:0010824)2.66695684
136DNA conformation change (GO:0071103)2.66305341
137rRNA transcription (GO:0009303)2.63870986
138spliceosomal tri-snRNP complex assembly (GO:0000244)2.63349520
139negative regulation of chromosome segregation (GO:0051985)2.57808660
140meiotic chromosome segregation (GO:0045132)2.56894058
141peptidyl-arginine omega-N-methylation (GO:0035247)2.56028017
142regulation of RNA export from nucleus (GO:0046831)2.55803403
143mitotic cell cycle (GO:0000278)2.54704606
144somatic recombination of immunoglobulin gene segments (GO:0016447)2.54521796

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.66682624
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.28886723
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.67636723
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.40008738
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.26920553
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.26747826
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.03337718
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.00349076
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.87866894
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.83965994
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83704303
12FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.82830873
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.79796809
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.79289096
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.64594650
16* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35731615
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.35339180
18* XRN2_22483619_ChIP-Seq_HELA_Human2.27942912
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.25259573
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.21749400
21* VDR_23849224_ChIP-Seq_CD4+_Human2.16990589
22* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.09330108
23DCP1A_22483619_ChIP-Seq_HELA_Human2.00251758
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.99036093
25FOXP3_21729870_ChIP-Seq_TREG_Human1.94237863
26ELF1_17652178_ChIP-ChIP_JURKAT_Human1.92940928
27* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.92777357
28MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.92600202
29AR_21909140_ChIP-Seq_LNCAP_Human1.87225774
30NANOG_18555785_ChIP-Seq_MESCs_Mouse1.83012099
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.82260830
32* GABP_19822575_ChIP-Seq_HepG2_Human1.78919572
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.76820582
34E2F1_21310950_ChIP-Seq_MCF-7_Human1.75561516
35* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.73687159
36* TTF2_22483619_ChIP-Seq_HELA_Human1.72861337
37* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.72437692
38EGR1_19374776_ChIP-ChIP_THP-1_Human1.71746828
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68051428
40* ELK1_19687146_ChIP-ChIP_HELA_Human1.67580674
41CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.66525860
42SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.66176545
43* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.65447003
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.59902749
45KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.55989344
46TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.53925803
47YY1_21170310_ChIP-Seq_MESCs_Mouse1.51203162
48ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.50839419
49CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.50536694
50* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49486239
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48726867
52STAT3_1855785_ChIP-Seq_MESCs_Mouse1.48601196
53* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.48386668
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46083709
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.45652125
56CIITA_25753668_ChIP-Seq_RAJI_Human1.45195116
57* SRF_21415370_ChIP-Seq_HL-1_Mouse1.43734859
58CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.40027418
59KDM5A_27292631_Chip-Seq_BREAST_Human1.38450777
60PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.35068426
61MYC_22102868_ChIP-Seq_BL_Human1.33163887
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.32580594
63* SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.31834231
64FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31498092
65SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28129597
66SALL1_21062744_ChIP-ChIP_HESCs_Human1.24312397
67CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24244911
68* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24155334
69ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18236564
70TFEB_21752829_ChIP-Seq_HELA_Human1.17567766
71SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17133301
72PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.16988459
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.16386977
74SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.16133436
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.15942328
76CHD1_26751641_Chip-Seq_LNCaP_Human1.13214467
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12994464
78* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12621637
79SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.11051727
80CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10471530
81* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07953283
82* SOX17_20123909_ChIP-Seq_XEN_Mouse1.06182636
83KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.05955360
84KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.05955360
85KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.05955360
86SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.04020282
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.03140766
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.02259407
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.02246362
90TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02231001
91KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01711371
92* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00345424
93CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00182477
94ZNF263_19887448_ChIP-Seq_K562_Human0.99670998
95BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.99338647
96E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98982502
97* ELK1_22589737_ChIP-Seq_MCF10A_Human0.98456564
98TBX5_21415370_ChIP-Seq_HL-1_Mouse0.97739980
99SPI1_23547873_ChIP-Seq_NB4_Human0.97668919
100DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95842441
101NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.93099782
102CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.92628845
103TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.92422788
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.90978992
105CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90303741
106SOX2_18692474_ChIP-Seq_MEFs_Mouse0.90009139
107* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.89704617
108MYC_18940864_ChIP-ChIP_HL60_Human0.89668973
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.86335030
110* NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84992088
111RBPJ_22232070_ChIP-Seq_NCS_Mouse0.84431543
112HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84160714
113ESR1_15608294_ChIP-ChIP_MCF-7_Human0.83680427
114* DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83386630
115SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.80931760
116PKCTHETA_26484144_Chip-Seq_BREAST_Human0.80187859
117EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.75571712
118CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.73514514
119FOXP1_21924763_ChIP-Seq_HESCs_Human0.72615018
120TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.72465108

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.20138646
2MP0004957_abnormal_blastocyst_morpholog4.27787508
3MP0010094_abnormal_chromosome_stability4.09802691
4MP0003111_abnormal_nucleus_morphology4.09763049
5MP0003077_abnormal_cell_cycle3.68640974
6MP0008057_abnormal_DNA_replication3.51618003
7MP0008058_abnormal_DNA_repair3.04904653
8MP0008007_abnormal_cellular_replicative2.77134516
9MP0003806_abnormal_nucleotide_metabolis2.63937112
10MP0008932_abnormal_embryonic_tissue2.42309256
11MP0003123_paternal_imprinting2.26699401
12MP0002877_abnormal_melanocyte_morpholog2.17235444
13MP0001730_embryonic_growth_arrest2.13916468
14MP0002396_abnormal_hematopoietic_system2.12045247
15MP0010352_gastrointestinal_tract_polyps2.07185650
16MP0000350_abnormal_cell_proliferation2.05570321
17MP0000537_abnormal_urethra_morphology2.02762839
18MP0003786_premature_aging1.96244432
19MP0009697_abnormal_copulation1.86238245
20MP0003718_maternal_effect1.82949484
21MP0010307_abnormal_tumor_latency1.82859561
22MP0000490_abnormal_crypts_of1.68677702
23MP0003186_abnormal_redox_activity1.66237691
24MP0003937_abnormal_limbs/digits/tail_de1.64973371
25MP0005380_embryogenesis_phenotype1.58471124
26MP0001672_abnormal_embryogenesis/_devel1.58471124
27MP0001697_abnormal_embryo_size1.56658092
28MP0009333_abnormal_splenocyte_physiolog1.49092726
29MP0002080_prenatal_lethality1.47868036
30MP0002019_abnormal_tumor_incidence1.42114107
31MP0003984_embryonic_growth_retardation1.41735920
32MP0002088_abnormal_embryonic_growth/wei1.39030508
33MP0000313_abnormal_cell_death1.37448973
34MP0004808_abnormal_hematopoietic_stem1.34520093
35MP0002086_abnormal_extraembryonic_tissu1.28363287
36MP0002085_abnormal_embryonic_tissue1.26881169
37MP0004197_abnormal_fetal_growth/weight/1.26311895
38MP0010030_abnormal_orbit_morphology1.24221393
39MP0004233_abnormal_muscle_weight1.23683062
40MP0002938_white_spotting1.22903230
41MP0004185_abnormal_adipocyte_glucose1.21581755
42MP0005187_abnormal_penis_morphology1.21428215
43MP0002697_abnormal_eye_size1.20528789
44MP0000858_altered_metastatic_potential1.20418480
45MP0002234_abnormal_pharynx_morphology1.20229586
46MP0002132_abnormal_respiratory_system1.16009790
47MP0002084_abnormal_developmental_patter1.13066212
48MP0003950_abnormal_plasma_membrane1.11264237
49MP0003567_abnormal_fetal_cardiomyocyte1.10844700
50MP0005023_abnormal_wound_healing1.10820364
51MP0008877_abnormal_DNA_methylation1.10542549
52MP0003942_abnormal_urinary_system1.09569591
53MP0000689_abnormal_spleen_morphology1.08891232
54MP0001286_abnormal_eye_development1.08494998
55MP0000762_abnormal_tongue_morphology1.07708251
56MP0003385_abnormal_body_wall1.07695835
57MP0002722_abnormal_immune_system1.06849216
58MP0003315_abnormal_perineum_morphology1.05412768
59MP0001661_extended_life_span1.04101180
60MP0001545_abnormal_hematopoietic_system1.03533823
61MP0005397_hematopoietic_system_phenotyp1.03533823
62MP0001346_abnormal_lacrimal_gland1.02606870
63MP0002398_abnormal_bone_marrow1.02082956
64MP0003763_abnormal_thymus_physiology1.00772481
65MP0000358_abnormal_cell_content/0.99831948
66MP0005076_abnormal_cell_differentiation0.98037832
67MP0003943_abnormal_hepatobiliary_system0.97700582
68MP0001835_abnormal_antigen_presentation0.97156714
69MP0003566_abnormal_cell_adhesion0.96951337
70MP0001853_heart_inflammation0.96259591
71MP0000566_synostosis0.95689731
72MP0009053_abnormal_anal_canal0.95021402
73MP0001299_abnormal_eye_distance/0.94498338
74MP0000703_abnormal_thymus_morphology0.92607456
75MP0005501_abnormal_skin_physiology0.90406463
76MP0002429_abnormal_blood_cell0.90165961
77MP0002210_abnormal_sex_determination0.89580387
78MP0002092_abnormal_eye_morphology0.88267158
79MP0003755_abnormal_palate_morphology0.87933893
80MP0003861_abnormal_nervous_system0.86755627
81MP0001293_anophthalmia0.86300085
82MP0000003_abnormal_adipose_tissue0.86043424
83MP0009379_abnormal_foot_pigmentation0.85961809
84MP0000428_abnormal_craniofacial_morphol0.84142270
85MP0003705_abnormal_hypodermis_morpholog0.83314988
86MP0006054_spinal_hemorrhage0.81471556
87MP0004133_heterotaxia0.80891326
88MP0001145_abnormal_male_reproductive0.80529109
89MP0002111_abnormal_tail_morphology0.79626325
90MP0003436_decreased_susceptibility_to0.79558929
91MP0003119_abnormal_digestive_system0.79478082
92MP0003935_abnormal_craniofacial_develop0.79381369
93MP0001764_abnormal_homeostasis0.77895818
94MP0005384_cellular_phenotype0.77791436
95MP0002233_abnormal_nose_morphology0.77670294
96MP0003221_abnormal_cardiomyocyte_apopto0.77085998
97MP0000716_abnormal_immune_system0.77078202
98MP0002160_abnormal_reproductive_system0.76674314
99MP0006036_abnormal_mitochondrial_physio0.76178234
100MP0001800_abnormal_humoral_immune0.76064622
101MP0005408_hypopigmentation0.75868904
102MP0003890_abnormal_embryonic-extraembry0.75208624
103MP0009703_decreased_birth_body0.75148998
104MP0009840_abnormal_foam_cell0.74834111
105MP0005389_reproductive_system_phenotype0.74483605
106MP0001119_abnormal_female_reproductive0.73850523
107MP0001727_abnormal_embryo_implantation0.73795912
108MP0000647_abnormal_sebaceous_gland0.73461343
109MP0005621_abnormal_cell_physiology0.72838215
110MP0005623_abnormal_meninges_morphology0.72339185
111MP0000534_abnormal_ureter_morphology0.71912836
112MP0002009_preneoplasia0.71037327
113MP0002452_abnormal_antigen_presenting0.70866228
114MP0004272_abnormal_basement_membrane0.70369193
115MP0002405_respiratory_system_inflammati0.70071796
116MP0003448_altered_tumor_morphology0.69693999
117MP0000627_abnormal_mammary_gland0.69482860
118MP0003941_abnormal_skin_development0.68899310
119MP0000579_abnormal_nail_morphology0.68764794
120MP0000598_abnormal_liver_morphology0.68547241
121MP0009785_altered_susceptibility_to0.67567363
122MP0003115_abnormal_respiratory_system0.67218728
123MP0001881_abnormal_mammary_gland0.67113473
124MP0000613_abnormal_salivary_gland0.66099834
125MP0001915_intracranial_hemorrhage0.66031168
126MP0003121_genomic_imprinting0.65977064
127MP0005266_abnormal_metabolism0.65416716
128MP0002114_abnormal_axial_skeleton0.64994663
129MP0009250_abnormal_appendicular_skeleto0.64935031
130MP0006072_abnormal_retinal_apoptosis0.64577729
131MP0002177_abnormal_outer_ear0.64567865
132MP0009672_abnormal_birth_weight0.64556152
133MP0002081_perinatal_lethality0.64441422
134MP0000653_abnormal_sex_gland0.64417307
135MP0000477_abnormal_intestine_morphology0.64297928
136MP0001929_abnormal_gametogenesis0.63937059
137MP0002420_abnormal_adaptive_immunity0.63923992
138MP0006292_abnormal_olfactory_placode0.63698669
139MP0001243_abnormal_dermal_layer0.63543302
140MP0001819_abnormal_immune_cell0.63205772
141MP0006035_abnormal_mitochondrial_morpho0.62100656
142MP0009780_abnormal_chondrocyte_physiolo0.61921781
143MP0001873_stomach_inflammation0.60985366
144MP0005025_abnormal_response_to0.60259752
145MP0000685_abnormal_immune_system0.60067778
146MP0010155_abnormal_intestine_physiology0.59125485
147MP0000750_abnormal_muscle_regeneration0.58954446
148MP0009278_abnormal_bone_marrow0.58526279
149MP0002723_abnormal_immune_serum0.57969290
150MP0005395_other_phenotype0.57659124

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.64274980
2Reticulocytopenia (HP:0001896)4.32490606
3Breast hypoplasia (HP:0003187)3.95358171
4Oral leukoplakia (HP:0002745)3.94015689
5Abnormality of cells of the erythroid lineage (HP:0012130)3.64072716
6Abnormal number of erythroid precursors (HP:0012131)3.43872157
7Carpal bone hypoplasia (HP:0001498)3.41877588
8Degeneration of anterior horn cells (HP:0002398)3.36532474
9Abnormality of the anterior horn cell (HP:0006802)3.36532474
10Rough bone trabeculation (HP:0100670)3.29400649
11Selective tooth agenesis (HP:0001592)3.25933612
12Colon cancer (HP:0003003)3.10885304
13Aplastic anemia (HP:0001915)3.08937958
14Chromsome breakage (HP:0040012)3.01302180
15Agnosia (HP:0010524)3.00516884
16Macrocytic anemia (HP:0001972)2.97458005
17Thrombocytosis (HP:0001894)2.89239752
18Patellar aplasia (HP:0006443)2.86962851
19Chromosomal breakage induced by crosslinking agents (HP:0003221)2.84720647
20Trismus (HP:0000211)2.79634135
21Cerebral hypomyelination (HP:0006808)2.74804198
22Aplasia/Hypoplasia of the patella (HP:0006498)2.71695678
23Medulloblastoma (HP:0002885)2.68214767
24Meckel diverticulum (HP:0002245)2.66075711
25Multiple enchondromatosis (HP:0005701)2.63566311
26Abnormality of the carotid arteries (HP:0005344)2.61403849
27Absent thumb (HP:0009777)2.59030222
28Pallor (HP:0000980)2.56112173
29Abnormality of the preputium (HP:0100587)2.55919408
30Abnormality of chromosome stability (HP:0003220)2.54804137
31Abnormality of pyrimidine metabolism (HP:0004353)2.54320442
32Abnormality of the ileum (HP:0001549)2.54017980
33Ependymoma (HP:0002888)2.51433546
34Premature graying of hair (HP:0002216)2.50743460
35Increased nuchal translucency (HP:0010880)2.48813277
36Myelodysplasia (HP:0002863)2.46719298
3711 pairs of ribs (HP:0000878)2.44374276
38Neoplasm of the pancreas (HP:0002894)2.41797349
39Abnormal trabecular bone morphology (HP:0100671)2.39871037
40Microretrognathia (HP:0000308)2.39625324
41Absent radius (HP:0003974)2.38715285
42High anterior hairline (HP:0009890)2.37106637
43Bone marrow hypocellularity (HP:0005528)2.36096228
44Entropion (HP:0000621)2.34370706
45Impulsivity (HP:0100710)2.34047876
46Abnormality of alanine metabolism (HP:0010916)2.31497400
47Hyperalaninemia (HP:0003348)2.31497400
48Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.31497400
49Rhabdomyosarcoma (HP:0002859)2.31383139
50Aplasia/Hypoplasia of the sacrum (HP:0008517)2.30079505
51Hyperacusis (HP:0010780)2.23673926
52Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.22409301
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.19759247
54Cellular immunodeficiency (HP:0005374)2.17797444
55Aplasia involving forearm bones (HP:0009822)2.16613554
56Absent forearm bone (HP:0003953)2.16613554
57Megaloblastic anemia (HP:0001889)2.13730144
58Hypoplasia of the pons (HP:0012110)2.13648376
59Amaurosis fugax (HP:0100576)2.13497041
60Abnormality of the pons (HP:0007361)2.13347894
61Progressive muscle weakness (HP:0003323)2.12817212
62Secondary amenorrhea (HP:0000869)2.11505907
63Premature ovarian failure (HP:0008209)2.09256011
64Horseshoe kidney (HP:0000085)2.03637188
65Abnormality of the labia minora (HP:0012880)2.02085696
66Tracheoesophageal fistula (HP:0002575)2.01760613
67Abnormal number of incisors (HP:0011064)2.01329519
68Insomnia (HP:0100785)2.01067825
69Duodenal stenosis (HP:0100867)2.00733653
70Small intestinal stenosis (HP:0012848)2.00733653
71Overriding aorta (HP:0002623)1.99207607
72Glossoptosis (HP:0000162)1.99206876
73Pancytopenia (HP:0001876)1.99107876
74Poikiloderma (HP:0001029)1.98984595
75Short thumb (HP:0009778)1.98355998
76Duplicated collecting system (HP:0000081)1.97593742
77Cortical dysplasia (HP:0002539)1.97382679
78Type I transferrin isoform profile (HP:0003642)1.94263639
79Sparse eyelashes (HP:0000653)1.93169046
80Lymphoma (HP:0002665)1.92811404
81Sloping forehead (HP:0000340)1.92292123
82IgM deficiency (HP:0002850)1.91889962
83Cerebellar dysplasia (HP:0007033)1.90099716
84Elfin facies (HP:0004428)1.89779459
85Hypoplasia of the capital femoral epiphysis (HP:0003090)1.87261929
86Basal cell carcinoma (HP:0002671)1.85247122
87Missing ribs (HP:0000921)1.85129696
88Abnormal lung lobation (HP:0002101)1.84357706
89Ectopic kidney (HP:0000086)1.83931989
90Nephroblastoma (Wilms tumor) (HP:0002667)1.83320381
91Abnormality of DNA repair (HP:0003254)1.83038941
92Supernumerary spleens (HP:0009799)1.82207834
93Irregular epiphyses (HP:0010582)1.79610723
94Lipid accumulation in hepatocytes (HP:0006561)1.79495780
95Triphalangeal thumb (HP:0001199)1.79253484
96Septate vagina (HP:0001153)1.77111403
97Squamous cell carcinoma (HP:0002860)1.76721759
98Increased hepatocellular lipid droplets (HP:0006565)1.76227012
99Spinal muscular atrophy (HP:0007269)1.76059083
100Increased serum lactate (HP:0002151)1.75726615
101Cafe-au-lait spot (HP:0000957)1.74722677
102Abnormality of reticulocytes (HP:0004312)1.74112717
103Tongue fasciculations (HP:0001308)1.73750026
104Neoplasm of the colon (HP:0100273)1.73695424
105Aplasia/hypoplasia of the humerus (HP:0006507)1.73289915
106Renal duplication (HP:0000075)1.73260261
107Abnormality of the duodenum (HP:0002246)1.71784622
108Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71712976
109Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71712976
110Cleft eyelid (HP:0000625)1.71483151
111Slender long bone (HP:0003100)1.69657558
112Atresia of the external auditory canal (HP:0000413)1.69245498
113Embryonal renal neoplasm (HP:0011794)1.68867898
114Partial agenesis of the corpus callosum (HP:0001338)1.67770295
115Atrophy/Degeneration involving motor neurons (HP:0007373)1.67556328
116Abnormality of the calcaneus (HP:0008364)1.66679739
117Facial cleft (HP:0002006)1.66646450
118Abnormality of the umbilical cord (HP:0010881)1.66116755
119Microvesicular hepatic steatosis (HP:0001414)1.66086798
120Abnormality of methionine metabolism (HP:0010901)1.65887497
121Aplasia/Hypoplasia involving the musculature (HP:0001460)1.64863666
122Ureteral duplication (HP:0000073)1.64853654
123Choanal atresia (HP:0000453)1.64431547
124Nausea (HP:0002018)1.64354848
125Increased serum pyruvate (HP:0003542)1.63822378
126Abnormality of glycolysis (HP:0004366)1.63822378
127Deviation of the thumb (HP:0009603)1.62983612
128Aseptic necrosis (HP:0010885)1.62013187
129Type II lissencephaly (HP:0007260)1.61725993
130Proximal placement of thumb (HP:0009623)1.61638358
131Testicular atrophy (HP:0000029)1.60562602
132Retinal dysplasia (HP:0007973)1.60365484
133Hypoplasia of the radius (HP:0002984)1.59959402
134Muscle fiber atrophy (HP:0100295)1.59853979
135Reduced antithrombin III activity (HP:0001976)1.59788462
136Cutaneous melanoma (HP:0012056)1.59207054
137Abnormality of the renal collecting system (HP:0004742)1.58306106
138Abnormality of the intrinsic pathway (HP:0010989)1.55560535
139Upper limb muscle weakness (HP:0003484)1.53859117
140Shoulder girdle muscle weakness (HP:0003547)1.50976760
141Glioma (HP:0009733)1.49563540
142Homocystinuria (HP:0002156)1.49130309
143Abnormality of homocysteine metabolism (HP:0010919)1.49130309
144Overlapping toe (HP:0001845)1.48347130
145Microglossia (HP:0000171)1.47332560
146Asymmetry of the thorax (HP:0001555)1.47180059
147Abnormality of cochlea (HP:0000375)1.46678659
148Postnatal microcephaly (HP:0005484)1.46127177
149Renovascular hypertension (HP:0100817)1.44976456
150Fibular aplasia (HP:0002990)1.44423595
151Duplication of thumb phalanx (HP:0009942)1.44416777
152Volvulus (HP:0002580)1.43573966

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.63609847
2WEE13.96266997
3EIF2AK13.45470111
4CDC73.07835647
5STK163.06892201
6TSSK62.66592591
7SRPK12.64090581
8NME22.49129169
9VRK22.40455691
10EIF2AK32.26682864
11TESK22.18650452
12NEK22.13529324
13NEK12.12073366
14PLK42.11209626
15TTK2.02648848
16BRSK22.02052104
17ICK1.96340122
18TLK11.95281169
19SMG11.85143038
20PLK11.82057284
21EPHA21.78423592
22ACVR1B1.76875419
23PASK1.73606588
24TAF11.72862487
25MKNK11.72259168
26VRK11.72194067
27RPS6KB21.69075538
28ZAK1.58734292
29LATS11.55285205
30AURKB1.54144352
31PLK31.53087062
32CDK71.46545037
33ATR1.45102093
34TRIB31.41814432
35RPS6KA41.41454638
36PNCK1.37320966
37PAK41.30904341
38TGFBR11.27659522
39CDK41.26084245
40ERBB41.24744456
41MKNK21.22291295
42MAP3K81.18899884
43STK101.18582042
44WNK41.13026967
45BCKDK1.12860368
46MAP2K71.12488187
47AURKA1.10851570
48PIM21.08914979
49FLT31.07414475
50CHEK21.04203216
51PBK1.03188575
52STK41.02884593
53DYRK31.01166784
54TESK11.00147529
55BRSK10.99824685
56EEF2K0.98398503
57PIM10.97014720
58CHEK10.96359773
59NUAK10.94383019
60LATS20.93570904
61CCNB10.93135396
62MAP4K10.88514925
63EIF2AK20.86959265
64SCYL20.86228110
65IRAK30.82330101
66BMPR1B0.78460828
67CDK120.74808855
68KDR0.74717160
69LRRK20.74529252
70AKT30.71844560
71NEK90.70332820
72MST1R0.70281281
73CSNK2A20.69408277
74PAK10.68982172
75CSNK2A10.68335942
76CDK20.67432609
77STK38L0.66770011
78ATM0.66304401
79BLK0.63896362
80ALK0.62848070
81MST40.62629097
82PKN20.62452118
83CSNK1E0.60916044
84TRIM280.59769894
85MAPKAPK50.58367102
86ZAP700.58033878
87MTOR0.56469068
88CDK60.56352646
89PRKCI0.55413873
90MAP3K30.54148121
91CSNK1A1L0.52771468
92IKBKB0.51370875
93PDK20.49405162
94MAP3K40.49386678
95MAP3K110.49055445
96STK30.48188958
97BTK0.47906832
98RPS6KA50.46480513
99AKT20.46001267
100ILK0.45638875
101MET0.45578282
102TEC0.45475029
103CAMK1G0.44756470
104DAPK10.44687106
105IRAK40.44242525
106MAPKAPK30.44212967
107TXK0.43981477
108CDK10.43671477
109JAK30.43448479
110PDK40.42108492
111PDK30.42108492
112MELK0.41619569
113PRKDC0.41349642
114PAK20.41323942
115CDK80.41085667
116MAP2K30.40357069
117NME10.39559033
118TYK20.39322270
119CAMK1D0.38628741
120FGFR10.38069395
121BRAF0.36951386
122PDGFRA0.36764996
123CSNK1G30.35927122
124STK390.34890383
125CDK180.34293339
126CDK150.33540009
127DYRK20.32709064
128RAF10.32553149
129CSF1R0.32455376
130CLK10.31975196
131BRD40.30005843
132CHUK0.27877886
133LIMK10.26776493
134ABL20.26617821
135KIT0.26306143

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.41768284
2Mismatch repair_Homo sapiens_hsa034303.79224819
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.63191921
4Ribosome_Homo sapiens_hsa030103.52965120
5Proteasome_Homo sapiens_hsa030503.52088918
6RNA polymerase_Homo sapiens_hsa030203.21811303
7Spliceosome_Homo sapiens_hsa030403.01324742
8One carbon pool by folate_Homo sapiens_hsa006703.00114061
9RNA transport_Homo sapiens_hsa030132.90453409
10Base excision repair_Homo sapiens_hsa034102.72215204
11Nucleotide excision repair_Homo sapiens_hsa034202.66121867
12Homologous recombination_Homo sapiens_hsa034402.55516821
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.46054011
14Pyrimidine metabolism_Homo sapiens_hsa002402.42179740
15Cell cycle_Homo sapiens_hsa041102.18636977
16Fanconi anemia pathway_Homo sapiens_hsa034601.77905878
17Non-homologous end-joining_Homo sapiens_hsa034501.66542062
18Basal transcription factors_Homo sapiens_hsa030221.60005140
19RNA degradation_Homo sapiens_hsa030181.59713521
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.43827037
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41845323
22p53 signaling pathway_Homo sapiens_hsa041151.39204832
23mRNA surveillance pathway_Homo sapiens_hsa030151.32637153
24Folate biosynthesis_Homo sapiens_hsa007901.25638050
25Purine metabolism_Homo sapiens_hsa002301.22532923
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.21878105
27Biosynthesis of amino acids_Homo sapiens_hsa012301.20796625
28Cysteine and methionine metabolism_Homo sapiens_hsa002701.19208469
29Selenocompound metabolism_Homo sapiens_hsa004501.18961218
30Systemic lupus erythematosus_Homo sapiens_hsa053221.16667152
31Epstein-Barr virus infection_Homo sapiens_hsa051691.16303202
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.14907403
33Pentose phosphate pathway_Homo sapiens_hsa000301.13614044
34Antigen processing and presentation_Homo sapiens_hsa046121.01750886
35Cyanoamino acid metabolism_Homo sapiens_hsa004601.01510572
36Protein export_Homo sapiens_hsa030600.94609415
37Lysine degradation_Homo sapiens_hsa003100.93950771
38Vitamin B6 metabolism_Homo sapiens_hsa007500.92587766
39Steroid biosynthesis_Homo sapiens_hsa001000.92135295
40Legionellosis_Homo sapiens_hsa051340.91896547
41Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91407074
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90000997
432-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89403757
44Herpes simplex infection_Homo sapiens_hsa051680.87612411
45Carbon metabolism_Homo sapiens_hsa012000.85476198
46Viral carcinogenesis_Homo sapiens_hsa052030.85047790
47Sulfur relay system_Homo sapiens_hsa041220.82679820
48Glutathione metabolism_Homo sapiens_hsa004800.82381148
49Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78349170
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.75451169
51Oxidative phosphorylation_Homo sapiens_hsa001900.73659189
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.72109793
53Propanoate metabolism_Homo sapiens_hsa006400.69464651
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.68203327
55Fructose and mannose metabolism_Homo sapiens_hsa000510.67101422
56Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.66501921
57Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64538039
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64233226
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.62095466
60Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61193664
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55351317
62Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.54622600
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54326415
64HTLV-I infection_Homo sapiens_hsa051660.52088024
65Alcoholism_Homo sapiens_hsa050340.51397142
66NF-kappa B signaling pathway_Homo sapiens_hsa040640.50570556
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.49588171
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48255950
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.47873348
70Primary immunodeficiency_Homo sapiens_hsa053400.47597257
71Basal cell carcinoma_Homo sapiens_hsa052170.46297536
72Galactose metabolism_Homo sapiens_hsa000520.46145539
73Apoptosis_Homo sapiens_hsa042100.45823321
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44430729
75Measles_Homo sapiens_hsa051620.42772186
76Small cell lung cancer_Homo sapiens_hsa052220.39853343
77Alzheimers disease_Homo sapiens_hsa050100.39575777
78Oocyte meiosis_Homo sapiens_hsa041140.38938781
79Butanoate metabolism_Homo sapiens_hsa006500.38424585
80Huntingtons disease_Homo sapiens_hsa050160.37516788
81Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.37315676
82N-Glycan biosynthesis_Homo sapiens_hsa005100.37132461
83Fatty acid elongation_Homo sapiens_hsa000620.37032893
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36768028
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35981543
86Hedgehog signaling pathway_Homo sapiens_hsa043400.35153799
87Melanoma_Homo sapiens_hsa052180.34551115
88Metabolic pathways_Homo sapiens_hsa011000.34056746
89Arginine and proline metabolism_Homo sapiens_hsa003300.33179459
90Chronic myeloid leukemia_Homo sapiens_hsa052200.31594658
91Vitamin digestion and absorption_Homo sapiens_hsa049770.31589193
92Thyroid cancer_Homo sapiens_hsa052160.31065148
93Wnt signaling pathway_Homo sapiens_hsa043100.31032697
94Colorectal cancer_Homo sapiens_hsa052100.29926593
95MicroRNAs in cancer_Homo sapiens_hsa052060.28822119
96RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.28621185
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.28435657
98Shigellosis_Homo sapiens_hsa051310.27549599
99Fatty acid metabolism_Homo sapiens_hsa012120.27157879
100Parkinsons disease_Homo sapiens_hsa050120.26793384
101Renin-angiotensin system_Homo sapiens_hsa046140.26711254
102Hematopoietic cell lineage_Homo sapiens_hsa046400.26615397
103Fatty acid biosynthesis_Homo sapiens_hsa000610.26127610
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.26029176
105Adherens junction_Homo sapiens_hsa045200.25999429
106Influenza A_Homo sapiens_hsa051640.25898517
107Transcriptional misregulation in cancer_Homo sapiens_hsa052020.25252968
108Pyruvate metabolism_Homo sapiens_hsa006200.24410741
109Pancreatic cancer_Homo sapiens_hsa052120.24140199
110HIF-1 signaling pathway_Homo sapiens_hsa040660.23911101
111TGF-beta signaling pathway_Homo sapiens_hsa043500.23390211
112Arginine biosynthesis_Homo sapiens_hsa002200.22895791
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.21532636
114Graft-versus-host disease_Homo sapiens_hsa053320.21460150
115Hepatitis B_Homo sapiens_hsa051610.21224760
116Pentose and glucuronate interconversions_Homo sapiens_hsa000400.21065157
117Arachidonic acid metabolism_Homo sapiens_hsa005900.20409378
118Asthma_Homo sapiens_hsa053100.20377971
119Leishmaniasis_Homo sapiens_hsa051400.19989911
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.16978628
121Allograft rejection_Homo sapiens_hsa053300.16124932
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16022705
123Bladder cancer_Homo sapiens_hsa052190.15933719
124Tight junction_Homo sapiens_hsa045300.15855198
125Caffeine metabolism_Homo sapiens_hsa002320.15378109
126Prostate cancer_Homo sapiens_hsa052150.14964025
127Other glycan degradation_Homo sapiens_hsa005110.13562719
128Notch signaling pathway_Homo sapiens_hsa043300.12825894
129Sulfur metabolism_Homo sapiens_hsa009200.12556598
130Nitrogen metabolism_Homo sapiens_hsa009100.11778907
131Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.11626490
132Hippo signaling pathway_Homo sapiens_hsa043900.11307744
133Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.10949479

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