RPL7P13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.86103699
2DNA deamination (GO:0045006)5.44558203
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.25062173
4ATP synthesis coupled proton transport (GO:0015986)5.25062173
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.98493514
6viral transcription (GO:0019083)4.89778099
7translational termination (GO:0006415)4.73871595
8behavioral response to nicotine (GO:0035095)4.59917063
9maturation of SSU-rRNA (GO:0030490)4.36641225
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.25373846
11ribosomal large subunit biogenesis (GO:0042273)4.25343527
12translational elongation (GO:0006414)4.18759469
13cotranslational protein targeting to membrane (GO:0006613)4.16886968
14protein targeting to ER (GO:0045047)4.14261095
15kynurenine metabolic process (GO:0070189)3.98443900
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.96586370
17establishment of protein localization to endoplasmic reticulum (GO:0072599)3.95844235
18protein localization to endoplasmic reticulum (GO:0070972)3.93359436
19ribosomal small subunit biogenesis (GO:0042274)3.91842256
20protein complex biogenesis (GO:0070271)3.89399358
21water-soluble vitamin biosynthetic process (GO:0042364)3.85440663
22protein neddylation (GO:0045116)3.80688960
23mitochondrial respiratory chain complex I assembly (GO:0032981)3.80074026
24NADH dehydrogenase complex assembly (GO:0010257)3.80074026
25mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.80074026
26chaperone-mediated protein transport (GO:0072321)3.74600746
27establishment of protein localization to mitochondrial membrane (GO:0090151)3.65327045
28tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.60706470
29RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.60706470
30preassembly of GPI anchor in ER membrane (GO:0016254)3.54853632
31mitochondrial respiratory chain complex assembly (GO:0033108)3.53762630
32fucose catabolic process (GO:0019317)3.52646221
33L-fucose metabolic process (GO:0042354)3.52646221
34L-fucose catabolic process (GO:0042355)3.52646221
35respiratory electron transport chain (GO:0022904)3.50496989
36electron transport chain (GO:0022900)3.49733905
37tryptophan catabolic process (GO:0006569)3.48454054
38indole-containing compound catabolic process (GO:0042436)3.48454054
39indolalkylamine catabolic process (GO:0046218)3.48454054
40viral life cycle (GO:0019058)3.47339964
41epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.43846616
42translational initiation (GO:0006413)3.41876434
43cellular protein complex disassembly (GO:0043624)3.39909194
44translation (GO:0006412)3.39853228
45nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.34017030
46nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.33669301
47negative regulation of telomere maintenance (GO:0032205)3.26002429
48exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.18481385
49negative regulation of T cell differentiation in thymus (GO:0033085)3.16047502
50regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.15722118
51GTP biosynthetic process (GO:0006183)3.13157165
52tryptophan metabolic process (GO:0006568)3.09757841
53purine nucleoside triphosphate biosynthetic process (GO:0009145)3.08684797
54maturation of 5.8S rRNA (GO:0000460)3.08499625
55purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.05710359
56ATP biosynthetic process (GO:0006754)3.03358736
57transcription elongation from RNA polymerase III promoter (GO:0006385)3.02817297
58termination of RNA polymerase III transcription (GO:0006386)3.02817297
59L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.02151573
60cellular component biogenesis (GO:0044085)2.98323208
61proteasome assembly (GO:0043248)2.96780736
62GPI anchor metabolic process (GO:0006505)2.94449477
63pseudouridine synthesis (GO:0001522)2.93628055
64regulation of isotype switching to IgG isotypes (GO:0048302)2.92524468
65mannosylation (GO:0097502)2.91540049
66respiratory chain complex IV assembly (GO:0008535)2.89556897
67indolalkylamine metabolic process (GO:0006586)2.89223261
68hydrogen ion transmembrane transport (GO:1902600)2.88551046
69rRNA modification (GO:0000154)2.81790585
70pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.81432224
71regulation of immunoglobulin secretion (GO:0051023)2.79913485
72GPI anchor biosynthetic process (GO:0006506)2.79792306
73positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.79135948
74proton transport (GO:0015992)2.78880412
75ribonucleoprotein complex biogenesis (GO:0022613)2.78763055
76protein complex disassembly (GO:0043241)2.77762501
77cytochrome complex assembly (GO:0017004)2.77725466
78piRNA metabolic process (GO:0034587)2.77460222
79hydrogen transport (GO:0006818)2.74619895
80positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.74511192
81rRNA metabolic process (GO:0016072)2.73921022
82positive regulation of prostaglandin secretion (GO:0032308)2.73837898
83regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.73473568
84rRNA processing (GO:0006364)2.73300265
85S-adenosylmethionine metabolic process (GO:0046500)2.71852023
86detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.70768901
87response to pheromone (GO:0019236)2.69515290
88amino acid salvage (GO:0043102)2.69206725
89L-methionine salvage (GO:0071267)2.69206725
90L-methionine biosynthetic process (GO:0071265)2.69206725
91peptidyl-histidine modification (GO:0018202)2.68883346
92nuclear-transcribed mRNA catabolic process (GO:0000956)2.67929566
93protein targeting to membrane (GO:0006612)2.67909699
94tRNA processing (GO:0008033)2.66879261
95macromolecular complex disassembly (GO:0032984)2.66545371
96somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.66523774
97isotype switching (GO:0045190)2.66523774
98somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.66523774
99aldehyde catabolic process (GO:0046185)2.63509333
100RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.62398263

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human3.78356043
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.69836411
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.24324587
4VDR_22108803_ChIP-Seq_LS180_Human3.15188712
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.07319303
6ZNF274_21170338_ChIP-Seq_K562_Hela2.95548388
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.91884183
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.80422316
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.60868768
10EZH2_22144423_ChIP-Seq_EOC_Human2.57740720
11BP1_19119308_ChIP-ChIP_Hs578T_Human2.43801017
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.29142591
13VDR_23849224_ChIP-Seq_CD4+_Human2.28667435
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.10770930
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.98962239
16ELF1_17652178_ChIP-ChIP_JURKAT_Human1.94770756
17ELK1_19687146_ChIP-ChIP_HELA_Human1.93723714
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.92411788
19FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90267335
20EWS_26573619_Chip-Seq_HEK293_Human1.80251093
21FOXP3_21729870_ChIP-Seq_TREG_Human1.78218699
22PCGF2_27294783_Chip-Seq_ESCs_Mouse1.75538968
23MYC_18940864_ChIP-ChIP_HL60_Human1.72992245
24MYC_18555785_ChIP-Seq_MESCs_Mouse1.72427410
25TP53_22573176_ChIP-Seq_HFKS_Human1.71005116
26PCGF2_27294783_Chip-Seq_NPCs_Mouse1.68761636
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.67074301
28IRF8_22096565_ChIP-ChIP_GC-B_Human1.65633684
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.63665396
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53756939
31IGF1R_20145208_ChIP-Seq_DFB_Human1.51332165
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.49459409
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.48987615
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.46418928
35ETV2_25802403_ChIP-Seq_MESCs_Mouse1.45469545
36ER_23166858_ChIP-Seq_MCF-7_Human1.42342902
37CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41335689
38GATA3_21878914_ChIP-Seq_MCF-7_Human1.37380919
39GATA3_26560356_Chip-Seq_TH2_Human1.37020441
40GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36535532
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34459117
42TDRD3_21172665_ChIP-Seq_MCF-7_Human1.33440542
43TAF2_19829295_ChIP-Seq_ESCs_Human1.30816502
44FOXA1_25329375_ChIP-Seq_VCAP_Human1.30544216
45FOXA1_27270436_Chip-Seq_PROSTATE_Human1.30544216
46CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29418279
47GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.28867956
48AR_20517297_ChIP-Seq_VCAP_Human1.28730210
49FUS_26573619_Chip-Seq_HEK293_Human1.27768986
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27385668
51HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.24815576
52AUTS2_25519132_ChIP-Seq_293T-REX_Human1.24780928
53IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.24433366
54CBP_20019798_ChIP-Seq_JUKART_Human1.24433366
55IRF1_19129219_ChIP-ChIP_H3396_Human1.22937617
56ERA_21632823_ChIP-Seq_H3396_Human1.18358552
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.16782799
58NANOG_20526341_ChIP-Seq_ESCs_Human1.16656383
59SOX2_19829295_ChIP-Seq_ESCs_Human1.16160604
60NANOG_19829295_ChIP-Seq_ESCs_Human1.16160604
61EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15107939
62NCOR_22424771_ChIP-Seq_293T_Human1.14658220
63IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.13827913
64TTF2_22483619_ChIP-Seq_HELA_Human1.13522537
65HOXB7_26014856_ChIP-Seq_BT474_Human1.12186357
66TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11264207
67FOXH1_21741376_ChIP-Seq_EPCs_Human1.10978776
68P300_19829295_ChIP-Seq_ESCs_Human1.10903552
69CREB1_15753290_ChIP-ChIP_HEK293T_Human1.10361838
70PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.09696931
71LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.08588297
72NFE2_27457419_Chip-Seq_LIVER_Mouse1.08111430
73YY1_21170310_ChIP-Seq_MESCs_Mouse1.07327512
74FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07043091
75SUZ12_27294783_Chip-Seq_NPCs_Mouse1.07002006
76TAF15_26573619_Chip-Seq_HEK293_Human1.06667877
77STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.06221254
78MYC_18358816_ChIP-ChIP_MESCs_Mouse1.04978406
79CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.04766690
80BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04745846
81MYC_19829295_ChIP-Seq_ESCs_Human1.02763138
82NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.02554963
83GABP_19822575_ChIP-Seq_HepG2_Human1.02423619
84KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02101655
85CTBP2_25329375_ChIP-Seq_LNCAP_Human1.01259523
86STAT1_20625510_ChIP-Seq_HELA_Human1.01168705
87CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.00750446
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.99004550
89P53_21459846_ChIP-Seq_SAOS-2_Human0.97709856
90FOXH1_21741376_ChIP-Seq_ESCs_Human0.96622153
91ELK1_22589737_ChIP-Seq_MCF10A_Human0.96574674
92PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96041294
93CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.93225330
94PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92093218
95FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91659421
96EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91184964
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.90447900
98GBX2_23144817_ChIP-Seq_PC3_Human0.90065277
99REST_21632747_ChIP-Seq_MESCs_Mouse0.89012279
100UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88398427

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.25768957
2MP0002138_abnormal_hepatobiliary_system2.93235331
3MP0006292_abnormal_olfactory_placode2.89444105
4MP0001835_abnormal_antigen_presentation2.78919708
5MP0002102_abnormal_ear_morphology2.78472273
6MP0008875_abnormal_xenobiotic_pharmacok2.73635786
7MP0005671_abnormal_response_to2.67776171
8MP0003646_muscle_fatigue2.49281665
9MP0008877_abnormal_DNA_methylation2.47129822
10MP0008872_abnormal_physiological_respon2.24513952
11MP0005646_abnormal_pituitary_gland2.12200456
12MP0001968_abnormal_touch/_nociception2.04224731
13MP0004142_abnormal_muscle_tone2.00297486
14MP0006072_abnormal_retinal_apoptosis1.91025358
15MP0003806_abnormal_nucleotide_metabolis1.84378438
16MP0001986_abnormal_taste_sensitivity1.79111903
17MP0004145_abnormal_muscle_electrophysio1.76535658
18MP0002837_dystrophic_cardiac_calcinosis1.75138766
19MP0005645_abnormal_hypothalamus_physiol1.73986455
20MP0008058_abnormal_DNA_repair1.66918460
21MP0002876_abnormal_thyroid_physiology1.63464154
22MP0002163_abnormal_gland_morphology1.58275202
23MP0001800_abnormal_humoral_immune1.57148700
24MP0005551_abnormal_eye_electrophysiolog1.56727229
25MP0002736_abnormal_nociception_after1.55887703
26MP0003787_abnormal_imprinting1.55666684
27MP0000685_abnormal_immune_system1.51549419
28MP0002148_abnormal_hypersensitivity_rea1.45246443
29MP0000372_irregular_coat_pigmentation1.43420309
30MP0009764_decreased_sensitivity_to1.39657143
31MP0004885_abnormal_endolymph1.39181417
32MP0008789_abnormal_olfactory_epithelium1.38613698
33MP0008775_abnormal_heart_ventricle1.36290143
34MP0006276_abnormal_autonomic_nervous1.33934052
35MP0005389_reproductive_system_phenotype1.33253458
36MP0002166_altered_tumor_susceptibility1.31877600
37MP0002272_abnormal_nervous_system1.31703519
38MP0005084_abnormal_gallbladder_morpholo1.30419429
39MP0002006_tumorigenesis1.29003933
40MP0004147_increased_porphyrin_level1.28883882
41MP0003724_increased_susceptibility_to1.28499361
42MP0002638_abnormal_pupillary_reflex1.27014791
43MP0003186_abnormal_redox_activity1.23688624
44MP0006036_abnormal_mitochondrial_physio1.22648353
45MP0001919_abnormal_reproductive_system1.20233856
46MP0001440_abnormal_grooming_behavior1.19477857
47MP0001970_abnormal_pain_threshold1.17007863
48MP0002653_abnormal_ependyma_morphology1.15821315
49MP0009333_abnormal_splenocyte_physiolog1.15668086
50MP0001905_abnormal_dopamine_level1.15390421
51MP0002733_abnormal_thermal_nociception1.15212969
52MP0005387_immune_system_phenotype1.13686003
53MP0001790_abnormal_immune_system1.13686003
54MP0002160_abnormal_reproductive_system1.12063106
55MP0005000_abnormal_immune_tolerance1.09703290
56MP0003866_abnormal_defecation1.09529980
57MP0009745_abnormal_behavioral_response1.08787900
58MP0002723_abnormal_immune_serum1.08103286
59MP0002095_abnormal_skin_pigmentation1.07803733
60MP0002234_abnormal_pharynx_morphology1.07504673
61MP0003252_abnormal_bile_duct1.06539667
62MP0003880_abnormal_central_pattern1.04407148
63MP0001873_stomach_inflammation1.02483101
64MP0003567_abnormal_fetal_cardiomyocyte1.02383480
65MP0001485_abnormal_pinna_reflex1.02125852
66MP0003718_maternal_effect1.02039094
67MP0002452_abnormal_antigen_presenting0.99373822
68MP0008995_early_reproductive_senescence0.99229378
69MP0005253_abnormal_eye_physiology0.98892679
70MP0009785_altered_susceptibility_to0.97606342
71MP0001529_abnormal_vocalization0.96635290
72MP0003786_premature_aging0.95241152
73MP0000631_abnormal_neuroendocrine_gland0.94495271
74MP0004043_abnormal_pH_regulation0.92760930
75MP0001293_anophthalmia0.91644739
76MP0002938_white_spotting0.91193883
77MP0002277_abnormal_respiratory_mucosa0.89738389
78MP0003011_delayed_dark_adaptation0.88268798
79MP0002420_abnormal_adaptive_immunity0.86396699
80MP0001819_abnormal_immune_cell0.86121029
81MP0000230_abnormal_systemic_arterial0.85373797
82MP0001765_abnormal_ion_homeostasis0.84969827
83MP0001853_heart_inflammation0.84719065
84MP0005085_abnormal_gallbladder_physiolo0.84515068
85MP0005379_endocrine/exocrine_gland_phen0.83115637
86MP0002735_abnormal_chemical_nociception0.82813369
87MP0001984_abnormal_olfaction0.82753321
88MP0002557_abnormal_social/conspecific_i0.81721929
89MP0001486_abnormal_startle_reflex0.80899018
90MP0003195_calcinosis0.79528067
91MP0005174_abnormal_tail_pigmentation0.79479543
92MP0005075_abnormal_melanosome_morpholog0.79322731
93MP0005636_abnormal_mineral_homeostasis0.79169978
94MP0005410_abnormal_fertilization0.77108841
95MP0005499_abnormal_olfactory_system0.76979551
96MP0005394_taste/olfaction_phenotype0.76979551
97MP0002572_abnormal_emotion/affect_behav0.74268669
98MP0005167_abnormal_blood-brain_barrier0.74124233
99MP0000427_abnormal_hair_cycle0.74044152
100MP0005195_abnormal_posterior_eye0.72616225

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.34701191
2Acute encephalopathy (HP:0006846)3.83030227
3Mitochondrial inheritance (HP:0001427)3.81830730
4Pancreatic cysts (HP:0001737)3.81559188
5Abnormal mitochondria in muscle tissue (HP:0008316)3.78244075
6Progressive macrocephaly (HP:0004481)3.69373671
7Increased CSF lactate (HP:0002490)3.62068069
8Congenital, generalized hypertrichosis (HP:0004540)3.61759788
9Hepatocellular necrosis (HP:0001404)3.57865340
10Abnormality of midbrain morphology (HP:0002418)3.52654570
11Molar tooth sign on MRI (HP:0002419)3.52654570
12Abnormality of cells of the erythroid lineage (HP:0012130)3.34587026
13Pancreatic fibrosis (HP:0100732)3.33158984
14Absent rod-and cone-mediated responses on ERG (HP:0007688)3.26961949
15Stomatitis (HP:0010280)3.23084386
163-Methylglutaconic aciduria (HP:0003535)3.20308557
17Hepatic necrosis (HP:0002605)3.06239163
18IgG deficiency (HP:0004315)2.97522309
19Nephronophthisis (HP:0000090)2.95989719
20Elevated erythrocyte sedimentation rate (HP:0003565)2.92678446
21Abnormal number of erythroid precursors (HP:0012131)2.92394138
22Congenital stationary night blindness (HP:0007642)2.92124630
23Abnormal rod and cone electroretinograms (HP:0008323)2.84360888
24Type II lissencephaly (HP:0007260)2.82401333
25Abolished electroretinogram (ERG) (HP:0000550)2.81095481
26Reticulocytopenia (HP:0001896)2.78626777
27Cerebral edema (HP:0002181)2.78583405
28True hermaphroditism (HP:0010459)2.78243276
29Increased serum lactate (HP:0002151)2.65243638
30Optic disc pallor (HP:0000543)2.63123731
31Increased hepatocellular lipid droplets (HP:0006565)2.57292603
32Lipid accumulation in hepatocytes (HP:0006561)2.55073664
33Abnormality of the renal medulla (HP:0100957)2.53163057
34Macrocytic anemia (HP:0001972)2.43483291
35Bile duct proliferation (HP:0001408)2.41510014
36Abnormal biliary tract physiology (HP:0012439)2.41510014
37Type 2 muscle fiber atrophy (HP:0003554)2.39855944
38Absent thumb (HP:0009777)2.37008185
39Cystic liver disease (HP:0006706)2.34644958
40Dynein arm defect of respiratory motile cilia (HP:0012255)2.33447344
41Absent/shortened dynein arms (HP:0200106)2.33447344
42Methylmalonic acidemia (HP:0002912)2.30935735
43Polydipsia (HP:0001959)2.30686667
44Abnormal drinking behavior (HP:0030082)2.30686667
45Lactic acidosis (HP:0003128)2.25970309
46Abnormality of the renal cortex (HP:0011035)2.22684026
47Pendular nystagmus (HP:0012043)2.22225402
48Aplasia/Hypoplasia of the spleen (HP:0010451)2.20978327
49Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.19436983
50Aplasia/hypoplasia of the uterus (HP:0008684)2.16262320
51Lethargy (HP:0001254)2.14162963
52Asplenia (HP:0001746)2.11022638
53Increased corneal curvature (HP:0100692)2.10931124
54Keratoconus (HP:0000563)2.10931124
55Renal Fanconi syndrome (HP:0001994)2.07950408
56Hypoproteinemia (HP:0003075)2.06825636
57Decreased activity of mitochondrial respiratory chain (HP:0008972)2.05864957
58Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.05864957
59Hypoplasia of the uterus (HP:0000013)2.01244150
60Polyuria (HP:0000103)2.01238016
61Abnormality of the prostate (HP:0008775)2.00718385
62Constricted visual fields (HP:0001133)2.00624649
63Respiratory failure (HP:0002878)2.00614239
64Abnormality of the proximal phalanges of the hand (HP:0009834)1.98571356
65Sclerocornea (HP:0000647)1.97468005
66Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.96529320
67Attenuation of retinal blood vessels (HP:0007843)1.95795195
68Muscle fiber atrophy (HP:0100295)1.95718569
69Increased IgM level (HP:0003496)1.95446016
70Abnormality of B cell number (HP:0010975)1.95161219
71Tubular atrophy (HP:0000092)1.92775027
72Abnormality of alanine metabolism (HP:0010916)1.91873943
73Hyperalaninemia (HP:0003348)1.91873943
74Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.91873943
75Increased intramyocellular lipid droplets (HP:0012240)1.91843531
76Decreased electroretinogram (ERG) amplitude (HP:0000654)1.91619882
77Progressive microcephaly (HP:0000253)1.90493212
78Thyroiditis (HP:0100646)1.85973078
79Leukodystrophy (HP:0002415)1.85651022
80Aplastic anemia (HP:0001915)1.84500630
81Pallor (HP:0000980)1.84086491
82B lymphocytopenia (HP:0010976)1.83422191
83Panhypogammaglobulinemia (HP:0003139)1.82429942
84Severe combined immunodeficiency (HP:0004430)1.81684830
85Methylmalonic aciduria (HP:0012120)1.81272273
86Supernumerary spleens (HP:0009799)1.80804534
87Exertional dyspnea (HP:0002875)1.79141543
88Decreased circulating renin level (HP:0003351)1.79048729
89Cerebellar dysplasia (HP:0007033)1.78222931
90Thyroid-stimulating hormone excess (HP:0002925)1.76540063
91Decreased central vision (HP:0007663)1.74701339
92Hypoplasia of the ulna (HP:0003022)1.73680463
93Colon cancer (HP:0003003)1.73380735
94Hypomagnesemia (HP:0002917)1.72714966
95Anencephaly (HP:0002323)1.72279762
96Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.70622246
97Abnormal respiratory motile cilium morphology (HP:0005938)1.70607348
98Abnormal respiratory epithelium morphology (HP:0012253)1.70607348
99CNS demyelination (HP:0007305)1.70033440
100Symphalangism affecting the phalanges of the hand (HP:0009773)1.69767757

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK13.23199498
2TXK3.20805206
3NUAK13.12293463
4WNK42.95102286
5STK162.83326463
6ZAK2.71758058
7ADRBK22.66326977
8FRK2.58201475
9BMPR1B2.53856438
10MAP4K22.51663076
11GRK12.43034216
12TAOK32.42132003
13STK392.05625146
14CDK191.96301231
15PINK11.92688856
16BCKDK1.80589074
17OXSR11.72816918
18VRK21.55091163
19MAP3K121.54940488
20CAMKK21.54146456
21MAP4K11.45432970
22PIK3CA1.41450293
23KIT1.39281267
24MST41.36372385
25DYRK21.33338956
26TIE11.30074623
27PLK41.28294933
28PHKG11.20419816
29PHKG21.20419816
30IKBKB1.15973517
31DAPK21.13652289
32CDK81.04053041
33MKNK21.03814650
34ITK1.03794873
35MUSK1.00857395
36TEC1.00128627
37MAPKAPK30.99512294
38VRK10.98701852
39WNK30.95571831
40FES0.95526057
41SYK0.95108151
42NME10.94804540
43MKNK10.94591977
44DAPK10.94351228
45INSRR0.93957639
46PLK20.90213206
47MYLK0.86483241
48RPS6KA50.85833947
49BMPR20.83307573
50TGFBR10.83201486
51EIF2AK30.81980344
52ADRBK10.77508491
53PRKCQ0.76025158
54SCYL20.72342678
55DAPK30.70739386
56NME20.70469089
57PIK3CG0.69731501
58MAP2K60.69425599
59GRK60.67734682
60BTK0.65825883
61PRKCG0.65707507
62LYN0.65141664
63CAMK10.63369219
64EIF2AK20.63019115
65ERBB30.60982924
66MAPK130.60666034
67GRK50.60236371
68IKBKE0.58393453
69CAMKK10.57580271
70ILK0.54175326
71LCK0.52059624
72CSNK1G30.51986231
73PRKCE0.51913122
74TRIM280.49500201
75ATR0.48592334
76MAPKAPK50.48477162
77EIF2AK10.47765480
78CSF1R0.46964086
79GRK70.44753310
80PLK30.44646009
81RPS6KA60.44453521
82PRKACA0.43812940
83OBSCN0.43745491
84MAP3K140.43584025
85KDR0.43153018
86PAK30.43006832
87CSNK1G20.42772528
88CSNK2A20.41266681
89PRKCA0.40296217
90CSNK1A10.39719345
91RPS6KA40.38733919
92IGF1R0.37783120
93DYRK30.37713052
94WNK10.34095529
95CHUK0.33929969
96NEK10.32274117
97CSNK2A10.31715369
98CAMK2A0.31413082
99MAP2K20.30637566
100PRKCI0.30312604

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.27323907
2Ribosome_Homo sapiens_hsa030104.21640755
3Oxidative phosphorylation_Homo sapiens_hsa001903.31680077
4Intestinal immune network for IgA production_Homo sapiens_hsa046723.26136889
5Allograft rejection_Homo sapiens_hsa053303.22465552
6Autoimmune thyroid disease_Homo sapiens_hsa053203.11009273
7Proteasome_Homo sapiens_hsa030502.70616958
8Parkinsons disease_Homo sapiens_hsa050122.67866738
9Graft-versus-host disease_Homo sapiens_hsa053322.56605937
10Protein export_Homo sapiens_hsa030602.40414212
11Type I diabetes mellitus_Homo sapiens_hsa049402.31869068
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.19250587
13RNA polymerase_Homo sapiens_hsa030202.05263942
14Caffeine metabolism_Homo sapiens_hsa002321.90160910
15Linoleic acid metabolism_Homo sapiens_hsa005911.82632717
16Alzheimers disease_Homo sapiens_hsa050101.79414865
17Huntingtons disease_Homo sapiens_hsa050161.77528084
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.73119750
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.72572528
20Primary immunodeficiency_Homo sapiens_hsa053401.57611736
21Cardiac muscle contraction_Homo sapiens_hsa042601.57418696
22RNA degradation_Homo sapiens_hsa030181.51778628
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.51592224
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50733929
25Antigen processing and presentation_Homo sapiens_hsa046121.44246922
26One carbon pool by folate_Homo sapiens_hsa006701.43289898
27Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.43174490
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.28280981
29Phototransduction_Homo sapiens_hsa047441.27682227
30Basal transcription factors_Homo sapiens_hsa030221.23185892
31Rheumatoid arthritis_Homo sapiens_hsa053231.21299049
32Nitrogen metabolism_Homo sapiens_hsa009101.19559880
33Tryptophan metabolism_Homo sapiens_hsa003801.15494333
34Propanoate metabolism_Homo sapiens_hsa006401.11788556
35Homologous recombination_Homo sapiens_hsa034401.10175936
36Arachidonic acid metabolism_Homo sapiens_hsa005901.01203945
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.00117032
38Fanconi anemia pathway_Homo sapiens_hsa034600.96003079
39Viral myocarditis_Homo sapiens_hsa054160.89046790
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88921907
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86897468
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85919544
43Pyrimidine metabolism_Homo sapiens_hsa002400.84342568
44Chemical carcinogenesis_Homo sapiens_hsa052040.80862922
45Hematopoietic cell lineage_Homo sapiens_hsa046400.80271804
46Systemic lupus erythematosus_Homo sapiens_hsa053220.79079091
47Ether lipid metabolism_Homo sapiens_hsa005650.78392412
48Peroxisome_Homo sapiens_hsa041460.77750224
49Staphylococcus aureus infection_Homo sapiens_hsa051500.76495146
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.75456655
51Olfactory transduction_Homo sapiens_hsa047400.74973230
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.72675872
53RNA transport_Homo sapiens_hsa030130.71520550
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.71000964
55Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70366463
56Non-homologous end-joining_Homo sapiens_hsa034500.69844663
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.69793167
58Nucleotide excision repair_Homo sapiens_hsa034200.68843548
59Fat digestion and absorption_Homo sapiens_hsa049750.68261044
60Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67923791
61Cysteine and methionine metabolism_Homo sapiens_hsa002700.66811969
62Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66251038
63Purine metabolism_Homo sapiens_hsa002300.64910095
64Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64738189
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.63772368
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63155770
67Regulation of autophagy_Homo sapiens_hsa041400.62959169
68Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59538436
69Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57057690
70Retinol metabolism_Homo sapiens_hsa008300.55797075
71Nicotine addiction_Homo sapiens_hsa050330.55409038
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53518779
73Sulfur metabolism_Homo sapiens_hsa009200.52478578
74Spliceosome_Homo sapiens_hsa030400.52387581
75Metabolic pathways_Homo sapiens_hsa011000.51467806
76Mismatch repair_Homo sapiens_hsa034300.47318133
77Leishmaniasis_Homo sapiens_hsa051400.46826862
78Butanoate metabolism_Homo sapiens_hsa006500.46613860
79Primary bile acid biosynthesis_Homo sapiens_hsa001200.45067360
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44925622
81Drug metabolism - other enzymes_Homo sapiens_hsa009830.43744926
82Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.42590790
83NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40380711
84Ovarian steroidogenesis_Homo sapiens_hsa049130.39334014
85NF-kappa B signaling pathway_Homo sapiens_hsa040640.38942883
86Collecting duct acid secretion_Homo sapiens_hsa049660.38677669
87Salivary secretion_Homo sapiens_hsa049700.37060571
88Fatty acid degradation_Homo sapiens_hsa000710.35274552
89Fatty acid elongation_Homo sapiens_hsa000620.34787931
90Taste transduction_Homo sapiens_hsa047420.34286458
91Selenocompound metabolism_Homo sapiens_hsa004500.34117516
92Morphine addiction_Homo sapiens_hsa050320.33734971
93Glycerolipid metabolism_Homo sapiens_hsa005610.32163933
94Serotonergic synapse_Homo sapiens_hsa047260.30101210
95Glutathione metabolism_Homo sapiens_hsa004800.28307591
96Base excision repair_Homo sapiens_hsa034100.27328979
97Jak-STAT signaling pathway_Homo sapiens_hsa046300.25736672
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.25317915
99T cell receptor signaling pathway_Homo sapiens_hsa046600.24204229
100Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20469475

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »