RPL7P17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cysteine metabolic process (GO:0006534)6.96755192
2serine family amino acid catabolic process (GO:0009071)6.30511967
3G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)6.07828500
4thalamus development (GO:0021794)5.98847111
5establishment of protein localization to mitochondrial membrane (GO:0090151)5.38016776
6urogenital system development (GO:0001655)5.31257265
7otic vesicle formation (GO:0030916)5.12711181
8peptidyl-histidine modification (GO:0018202)5.09236262
9positive regulation of mitochondrial membrane permeability (GO:0035794)4.72202035
10positive regulation of growth hormone secretion (GO:0060124)4.60166805
11sulfur amino acid catabolic process (GO:0000098)4.25452437
12positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)4.24882428
13heart valve formation (GO:0003188)4.19127639
14lactation (GO:0007595)4.06756765
15negative regulation of axon guidance (GO:1902668)4.03953125
16regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.98369290
17radial glial cell differentiation (GO:0060019)3.94594778
18cartilage morphogenesis (GO:0060536)3.84448990
19protein K6-linked ubiquitination (GO:0085020)3.83486863
20spinal cord development (GO:0021510)3.82749674
21regulation of growth hormone secretion (GO:0060123)3.79568816
22kinetochore organization (GO:0051383)3.74526211
23somite development (GO:0061053)3.68037225
24intra-S DNA damage checkpoint (GO:0031573)3.63284566
25limb bud formation (GO:0060174)3.63183085
26positive regulation of neuroblast proliferation (GO:0002052)3.59911440
27negative regulation of astrocyte differentiation (GO:0048712)3.57186405
28behavioral response to ethanol (GO:0048149)3.56137582
29L-serine metabolic process (GO:0006563)3.53745808
30determination of adult lifespan (GO:0008340)3.51700183
31regulation of cell proliferation involved in heart morphogenesis (GO:2000136)3.47272755
32serine family amino acid metabolic process (GO:0009069)3.42676786
33regulation of DNA endoreduplication (GO:0032875)3.38760490
34mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)3.35503470
35positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021103.35503470
36cytoplasmic mRNA processing body assembly (GO:0033962)3.34262783
37growth hormone secretion (GO:0030252)3.33176102
38dopaminergic neuron differentiation (GO:0071542)3.31588028
39retinal ganglion cell axon guidance (GO:0031290)3.31172068
40notochord development (GO:0030903)3.30526640
41negative regulation of interleukin-1 beta production (GO:0032691)3.29739251
42replication fork processing (GO:0031297)3.28234141
43intracellular protein transmembrane import (GO:0044743)3.18281621
44negative regulation of histone methylation (GO:0031061)3.17681859
45positive regulation of protein export from nucleus (GO:0046827)3.17127593
46negative regulation of oligodendrocyte differentiation (GO:0048715)3.16883483
47keratinocyte development (GO:0003334)3.12154468
48negative regulation by host of viral transcription (GO:0043922)3.11642710
49positive regulation of cellular response to insulin stimulus (GO:1900078)3.09654880
50regulation of norepinephrine secretion (GO:0014061)3.08460007
51regulation of non-canonical Wnt signaling pathway (GO:2000050)3.08267334
52centriole replication (GO:0007099)3.06012968
53midbrain development (GO:0030901)3.05282236
54toxin transport (GO:1901998)3.02099185
55endocardial cushion morphogenesis (GO:0003203)3.01426886
56regulation of insulin-like growth factor receptor signaling pathway (GO:0043567)2.95808669
57meiotic chromosome segregation (GO:0045132)2.93232438
58mammary gland epithelial cell differentiation (GO:0060644)2.91249750
59negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.88200452
60water-soluble vitamin biosynthetic process (GO:0042364)2.86288168
61photoreceptor cell differentiation (GO:0046530)2.85379401
62eye photoreceptor cell differentiation (GO:0001754)2.85379401
63positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.81602918
64cellular response to cholesterol (GO:0071397)2.79090756
65retinal cone cell development (GO:0046549)2.78102220
66negative regulation of interleukin-1 production (GO:0032692)2.77969790
67epithelial tube branching involved in lung morphogenesis (GO:0060441)2.74922862
68DNA catabolic process, exonucleolytic (GO:0000738)2.74885295
69negative regulation of alpha-beta T cell differentiation (GO:0046639)2.74002535
70lateral sprouting from an epithelium (GO:0060601)2.71064278
71sleep (GO:0030431)2.70294060
72DNA ligation (GO:0006266)2.69408043
73regulation of neuroblast proliferation (GO:1902692)2.67930851
74cellular response to sterol (GO:0036315)2.67886782
75L-fucose metabolic process (GO:0042354)2.67686064
76L-fucose catabolic process (GO:0042355)2.67686064
77fucose catabolic process (GO:0019317)2.67686064
78kinetochore assembly (GO:0051382)2.67150300
79righting reflex (GO:0060013)2.66058753
80tongue development (GO:0043586)2.65151117
81positive regulation of myoblast differentiation (GO:0045663)2.64557391
82mitotic metaphase plate congression (GO:0007080)2.64324976
83hair follicle development (GO:0001942)2.64217755
84DNA double-strand break processing (GO:0000729)2.58168878
85photoreceptor cell development (GO:0042461)2.53822697
86regulation of glucose import in response to insulin stimulus (GO:2001273)2.53033985
87regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.52606163
88intraciliary transport (GO:0042073)2.52413150
89regulation of skeletal muscle fiber development (GO:0048742)2.51996626
90regulation of histone H3-K27 methylation (GO:0061085)2.51934165
91recombinational repair (GO:0000725)2.51550282
92double-strand break repair via homologous recombination (GO:0000724)2.50102420
93T cell lineage commitment (GO:0002360)2.49891905
94neural crest cell development (GO:0014032)2.48908475
95negative regulation of JUN kinase activity (GO:0043508)2.48544691
96primitive streak formation (GO:0090009)2.47992366
97cranial nerve development (GO:0021545)2.47900807
98eye photoreceptor cell development (GO:0042462)2.47458883
99secretion by tissue (GO:0032941)2.47257921
100metaphase plate congression (GO:0051310)2.47231632

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.69130649
2CEBPD_23245923_ChIP-Seq_MEFs_Mouse3.26996040
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.25202686
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.21728301
5EST1_17652178_ChIP-ChIP_JURKAT_Human2.95017264
6E2F7_22180533_ChIP-Seq_HELA_Human2.89931097
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.68800108
8ELK1_19687146_ChIP-ChIP_HELA_Human2.61731771
9FUS_26573619_Chip-Seq_HEK293_Human2.60987399
10EWS_26573619_Chip-Seq_HEK293_Human2.52685969
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.45382061
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.39352836
13POU3F2_20337985_ChIP-ChIP_501MEL_Human2.25942348
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.22272293
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.20500978
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.16302324
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.09160535
18P300_19829295_ChIP-Seq_ESCs_Human2.03319063
19FLI1_27457419_Chip-Seq_LIVER_Mouse1.99780521
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.99690068
21GABP_17652178_ChIP-ChIP_JURKAT_Human1.94772102
22MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91325988
23ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84407220
24BCAT_22108803_ChIP-Seq_LS180_Human1.82017764
25IGF1R_20145208_ChIP-Seq_DFB_Human1.76937880
26VDR_22108803_ChIP-Seq_LS180_Human1.73556731
27TAF15_26573619_Chip-Seq_HEK293_Human1.73142563
28AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.69713974
29PIAS1_25552417_ChIP-Seq_VCAP_Human1.63979098
30FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.63928889
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.63201948
32MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.61964242
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.58539452
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52172611
35OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51400040
36CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48010179
37TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46086779
38POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46086779
39PADI4_21655091_ChIP-ChIP_MCF-7_Human1.45713799
40POU5F1_16153702_ChIP-ChIP_HESCs_Human1.45483976
41PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.44259918
42TCF4_22108803_ChIP-Seq_LS180_Human1.42648312
43NOTCH1_21737748_ChIP-Seq_TLL_Human1.41839548
44PCGF2_27294783_Chip-Seq_ESCs_Mouse1.39952363
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39547052
46CBP_20019798_ChIP-Seq_JUKART_Human1.39547052
47FOXP3_21729870_ChIP-Seq_TREG_Human1.39210815
48IRF1_19129219_ChIP-ChIP_H3396_Human1.38435762
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.37668873
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.35360541
51EZH2_22144423_ChIP-Seq_EOC_Human1.30361201
52KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.30252206
53TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27090072
54EGR1_23403033_ChIP-Seq_LIVER_Mouse1.26826240
55CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26652767
56STAT3_23295773_ChIP-Seq_U87_Human1.26232177
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25328753
58VDR_23849224_ChIP-Seq_CD4+_Human1.24654693
59SMAD3_21741376_ChIP-Seq_EPCs_Human1.24495371
60MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21501752
61NANOG_18555785_Chip-Seq_ESCs_Mouse1.20342093
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.19104772
63CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.18739679
64ER_23166858_ChIP-Seq_MCF-7_Human1.18235589
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17858497
66ARNT_22903824_ChIP-Seq_MCF-7_Human1.16801590
67EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.16355842
68MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.15851230
69PKCTHETA_26484144_Chip-Seq_BREAST_Human1.14777784
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11241797
71NCOR_22424771_ChIP-Seq_293T_Human1.10644675
72TRIM28_21343339_ChIP-Seq_HEK293_Human1.09245367
73SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.08718915
74NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08295888
75NFE2_27457419_Chip-Seq_LIVER_Mouse1.08118115
76MYC_18940864_ChIP-ChIP_HL60_Human1.07974471
77SOX2_19829295_ChIP-Seq_ESCs_Human1.07902613
78NANOG_19829295_ChIP-Seq_ESCs_Human1.07902613
79EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.07720097
80P53_22387025_ChIP-Seq_ESCs_Mouse1.07232522
81EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06358956
82AR_21572438_ChIP-Seq_LNCaP_Human1.06207007
83SOX2_16153702_ChIP-ChIP_HESCs_Human1.04647595
84LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04428997
85SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.03953448
86ETS1_20019798_ChIP-Seq_JURKAT_Human1.03437895
87TP53_16413492_ChIP-PET_HCT116_Human1.02234948
88RUNX2_22187159_ChIP-Seq_PCA_Human1.01673101
89JUN_21703547_ChIP-Seq_K562_Human1.01384772
90CDX2_22108803_ChIP-Seq_LS180_Human1.01286003
91GBX2_23144817_ChIP-Seq_PC3_Human1.00751711
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00611197
93PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99887419
94EZH2_27294783_Chip-Seq_NPCs_Mouse0.99849786
95STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.99776453
96RXR_22108803_ChIP-Seq_LS180_Human0.99176316
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.99154281
98SMAD4_21799915_ChIP-Seq_A2780_Human0.98591058
99E2F1_18555785_Chip-Seq_ESCs_Mouse0.98236718
100P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96142445

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001529_abnormal_vocalization5.12882468
2MP0003136_yellow_coat_color2.88199411
3MP0010094_abnormal_chromosome_stability2.71062370
4MP0008057_abnormal_DNA_replication2.55918887
5MP0003880_abnormal_central_pattern2.51533009
6MP0005085_abnormal_gallbladder_physiolo2.45222210
7MP0008058_abnormal_DNA_repair2.04213929
8MP0002822_catalepsy14.7778613
9MP0004043_abnormal_pH_regulation1.92000519
10MP0002282_abnormal_trachea_morphology1.72902429
11MP0000383_abnormal_hair_follicle1.72820363
12MP0003693_abnormal_embryo_hatching1.66577488
13MP0005171_absent_coat_pigmentation1.65893492
14MP0001346_abnormal_lacrimal_gland1.63152465
15MP0003868_abnormal_feces_composition1.61404856
16MP0002928_abnormal_bile_duct1.52831707
17MP0000372_irregular_coat_pigmentation1.44138045
18MP0005408_hypopigmentation1.42854595
19MP0002102_abnormal_ear_morphology1.32724065
20MP0010307_abnormal_tumor_latency1.30926344
21MP0010678_abnormal_skin_adnexa1.30837233
22MP0006072_abnormal_retinal_apoptosis1.30496290
23MP0008961_abnormal_basal_metabolism1.29937490
24MP0005174_abnormal_tail_pigmentation1.20528790
25MP0002132_abnormal_respiratory_system1.19305874
26MP0000015_abnormal_ear_pigmentation1.18795357
27MP0002095_abnormal_skin_pigmentation1.17983326
28MP0008872_abnormal_physiological_respon1.16201530
29MP0003941_abnormal_skin_development1.15308051
30MP0002751_abnormal_autonomic_nervous1.15219320
31MP0002653_abnormal_ependyma_morphology1.13543484
32MP0003077_abnormal_cell_cycle1.12737751
33MP0000569_abnormal_digit_pigmentation1.12229615
34MP0005084_abnormal_gallbladder_morpholo1.11890648
35MP0000427_abnormal_hair_cycle1.11646451
36MP0003937_abnormal_limbs/digits/tail_de1.08994349
37MP0001293_anophthalmia1.08677504
38MP0001881_abnormal_mammary_gland1.04809827
39MP0005386_behavior/neurological_phenoty1.03671557
40MP0004924_abnormal_behavior1.03671557
41MP0001873_stomach_inflammation1.03318053
42MP0005409_darkened_coat_color1.01844919
43MP0001486_abnormal_startle_reflex0.94471678
44MP0003111_abnormal_nucleus_morphology0.91387320
45MP0003806_abnormal_nucleotide_metabolis0.88877485
46MP0000631_abnormal_neuroendocrine_gland0.87950901
47MP0005253_abnormal_eye_physiology0.83869471
48MP0002938_white_spotting0.81266816
49MP0004145_abnormal_muscle_electrophysio0.79530347
50MP0005075_abnormal_melanosome_morpholog0.78227257
51MP0005248_abnormal_Harderian_gland0.77296964
52MP0003950_abnormal_plasma_membrane0.76876162
53MP0004957_abnormal_blastocyst_morpholog0.76830114
54MP0000647_abnormal_sebaceous_gland0.74697860
55MP0002249_abnormal_larynx_morphology0.73591790
56MP0002295_abnormal_pulmonary_circulatio0.73107854
57MP0004085_abnormal_heartbeat0.68678330
58MP0005391_vision/eye_phenotype0.67305215
59MP0003755_abnormal_palate_morphology0.66883512
60MP0001905_abnormal_dopamine_level0.65738796
61MP0001286_abnormal_eye_development0.65698629
62MP0001944_abnormal_pancreas_morphology0.64699839
63MP0000613_abnormal_salivary_gland0.64658911
64MP0001501_abnormal_sleep_pattern0.64263043
65MP0003646_muscle_fatigue0.63401430
66MP0006035_abnormal_mitochondrial_morpho0.62088978
67MP0003718_maternal_effect0.59289204
68MP0001664_abnormal_digestion0.58448333
69MP0000579_abnormal_nail_morphology0.58045462
70MP0005551_abnormal_eye_electrophysiolog0.56288745
71MP0003828_pulmonary_edema0.55606613
72MP0002932_abnormal_joint_morphology0.55347002
73MP0001324_abnormal_eye_pigmentation0.54184179
74MP0006292_abnormal_olfactory_placode0.52639548
75MP0005266_abnormal_metabolism0.51261497
76MP0003959_abnormal_lean_body0.50658713
77MP0000467_abnormal_esophagus_morphology0.49774567
78MP0000627_abnormal_mammary_gland0.48794667
79MP0002736_abnormal_nociception_after0.48532422
80MP0001968_abnormal_touch/_nociception0.47775834
81MP0005220_abnormal_exocrine_pancreas0.46519656
82MP0008932_abnormal_embryonic_tissue0.46035107
83MP0009745_abnormal_behavioral_response0.45540850
84MP0002697_abnormal_eye_size0.45299598
85MP0002111_abnormal_tail_morphology0.44553797
86MP0005448_abnormal_energy_balance0.41948334
87MP0003942_abnormal_urinary_system0.39351958
88MP0005195_abnormal_posterior_eye0.39082768
89MP0001697_abnormal_embryo_size0.38221318
90MP0001188_hyperpigmentation0.37251205
91MP0003936_abnormal_reproductive_system0.36808916
92MP0002109_abnormal_limb_morphology0.35943192
93MP0006036_abnormal_mitochondrial_physio0.35400790
94MP0002735_abnormal_chemical_nociception0.35040557
95MP0002075_abnormal_coat/hair_pigmentati0.34820358
96MP0001853_heart_inflammation0.34527869
97MP0005334_abnormal_fat_pad0.34510313
98MP0003938_abnormal_ear_development0.33933207
99MP0002092_abnormal_eye_morphology0.33717711
100MP0001851_eye_inflammation0.31005588

Predicted human phenotypes

RankGene SetZ-score
1Dyschromatopsia (HP:0007641)5.00007062
2Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.88023396
3Central scotoma (HP:0000603)3.71573297
4Hepatocellular necrosis (HP:0001404)3.65139885
5Pancreatic cysts (HP:0001737)3.58946895
6True hermaphroditism (HP:0010459)3.53241131
7Intestinal atresia (HP:0011100)3.20678500
811 pairs of ribs (HP:0000878)3.16299711
9Tubulointerstitial fibrosis (HP:0005576)2.92806332
10Hepatic necrosis (HP:0002605)2.92526316
11Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.87029545
12Short 4th metacarpal (HP:0010044)2.87029545
13Congenital, generalized hypertrichosis (HP:0004540)2.84181864
14Atonic seizures (HP:0010819)2.80998449
15Pancreatic fibrosis (HP:0100732)2.78709784
16Asplenia (HP:0001746)2.71235618
17Febrile seizures (HP:0002373)2.71037518
18Carpal bone hypoplasia (HP:0001498)2.70554124
19Abnormality of the ileum (HP:0001549)2.59858988
20Aplasia/Hypoplasia of the uvula (HP:0010293)2.57401390
21Aplasia/Hypoplasia of the sternum (HP:0006714)2.55622006
22Vertebral hypoplasia (HP:0008417)2.53097251
23Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.53097251
24Delayed CNS myelination (HP:0002188)2.52478006
25Tubulointerstitial abnormality (HP:0001969)2.50395979
26Gastrointestinal atresia (HP:0002589)2.47580557
27Abnormality of the renal cortex (HP:0011035)2.47175778
28Abnormality of chromosome stability (HP:0003220)2.45713363
29Aplasia/Hypoplasia of the spleen (HP:0010451)2.36160566
30Congenital stationary night blindness (HP:0007642)2.34811985
31Abnormality of midbrain morphology (HP:0002418)2.34627035
32Molar tooth sign on MRI (HP:0002419)2.34627035
33Small intestinal stenosis (HP:0012848)2.34504501
34Duodenal stenosis (HP:0100867)2.34504501
35Meckel diverticulum (HP:0002245)2.33355802
36Pigmentary retinal degeneration (HP:0001146)2.30738656
37Abnormal lung lobation (HP:0002101)2.29791855
38Abnormal drinking behavior (HP:0030082)2.28106613
39Polydipsia (HP:0001959)2.28106613
40Abnormality of the preputium (HP:0100587)2.22879474
41Acute necrotizing encephalopathy (HP:0006965)2.22101150
42Abnormality of the carotid arteries (HP:0005344)2.21239269
43Tubular atrophy (HP:0000092)2.21032993
44Rhinitis (HP:0012384)2.20972935
45Horizontal nystagmus (HP:0000666)2.20770991
46Abnormal sex determination (HP:0012244)2.19746795
47Sex reversal (HP:0012245)2.19746795
48Abnormal respiratory motile cilium physiology (HP:0012261)2.17275005
49Pancreatic islet-cell hyperplasia (HP:0004510)2.16672546
50Hypothermia (HP:0002045)2.14028413
51Abnormal mitochondria in muscle tissue (HP:0008316)2.11240758
52Abnormality of endocrine pancreas physiology (HP:0012093)2.09452527
53Abnormality of the pancreatic islet cells (HP:0006476)2.09452527
54Long clavicles (HP:0000890)2.07638460
55Abnormality of the duodenum (HP:0002246)2.06869537
56Chronic bronchitis (HP:0004469)2.06702461
57Sloping forehead (HP:0000340)2.06567188
58Tented upper lip vermilion (HP:0010804)2.06392561
59Missing ribs (HP:0000921)2.04859435
60Abnormality of the fovea (HP:0000493)2.03579512
61Hypoplasia of the thymus (HP:0000778)2.02774770
62Fibular hypoplasia (HP:0003038)2.01390853
63Constricted visual fields (HP:0001133)2.01348497
64Nephroblastoma (Wilms tumor) (HP:0002667)2.00924407
65Abnormality of the diencephalon (HP:0010662)1.99607590
66Progressive inability to walk (HP:0002505)1.97097938
67Hyperventilation (HP:0002883)1.95002543
68Aqueductal stenosis (HP:0002410)1.93724036
69Aplasia/Hypoplasia of the tongue (HP:0010295)1.92886615
70Progressive macrocephaly (HP:0004481)1.92266072
71Embryonal renal neoplasm (HP:0011794)1.89579974
72Aplasia/Hypoplasia of the fovea (HP:0008060)1.89119629
73Hypoplasia of the fovea (HP:0007750)1.89119629
74Aplasia/Hypoplasia involving the vertebral column (HP:0008518)1.88892213
75Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.85572037
76Abnormality of chromosome segregation (HP:0002916)1.84836021
77Renal cortical cysts (HP:0000803)1.81709081
78Colon cancer (HP:0003003)1.81195948
79Neonatal short-limb short stature (HP:0008921)1.81186595
80Poor head control (HP:0002421)1.80871727
81Scotoma (HP:0000575)1.80781790
82Dialeptic seizures (HP:0011146)1.80267831
83Stenosis of the external auditory canal (HP:0000402)1.79942329
84Abnormality of the axillary hair (HP:0100134)1.79417599
85Abnormality of secondary sexual hair (HP:0009888)1.79417599
86Medial flaring of the eyebrow (HP:0010747)1.79222742
87Growth hormone deficiency (HP:0000824)1.78546871
88Abnormal foot bone ossification (HP:0010675)1.78220930
89Abnormality of the proximal phalanges of the hand (HP:0009834)1.77197231
90Increased nuchal translucency (HP:0010880)1.77082307
91Abnormality of the 4th metacarpal (HP:0010012)1.76563190
92Vitreoretinal degeneration (HP:0000655)1.76181772
93Myelodysplasia (HP:0002863)1.73935488
94Aplasia/Hypoplasia of the fibula (HP:0006492)1.73820052
95Duplicated collecting system (HP:0000081)1.73515085
96Hypopigmentation of the fundus (HP:0007894)1.73420766
97Clubbing of toes (HP:0100760)1.71022062
98Relative macrocephaly (HP:0004482)1.70166606
99Hemiparesis (HP:0001269)1.69029085
100Acute encephalopathy (HP:0006846)1.68437415

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K26.71886494
2MAPK154.41543774
3PNCK4.27409563
4WEE13.28248347
5FRK2.74167064
6EIF2AK32.72228451
7CDK122.45797338
8BRD42.24459697
9MKNK22.18454776
10VRK12.06942559
11CCNB12.05839619
12TSSK61.91480736
13TAOK11.81473015
14BRSK21.78141613
15PLK31.74866912
16BLK1.64543628
17TLK11.62668944
18SRPK11.61503477
19EIF2AK21.57539157
20CSNK1G11.51426477
21TNIK1.43229170
22AKT31.41576735
23MAP3K101.39833443
24CDC71.39492768
25BMPR1B1.36181381
26CSNK1A1L1.34301713
27ACVR1B1.33591062
28MKNK11.31709528
29ZAK1.26498450
30TAF11.25577946
31PLK41.18780784
32DYRK31.17018499
33BUB11.12394507
34VRK21.10885774
35OXSR11.03987152
36ATR1.02913121
37RIPK41.01852242
38CSNK1G21.00403615
39STK390.99664197
40CSNK1G30.96968286
41EPHA40.96505300
42TGFBR10.92692789
43WNK30.91019573
44FGFR20.89676926
45PASK0.88224942
46NEK60.86708505
47PLK20.83660983
48ERBB30.83215930
49TXK0.82158514
50TRPM70.80617618
51MELK0.78885012
52YES10.76364736
53CDK30.74797577
54BCKDK0.72237346
55MAP3K70.66002469
56ADRBK20.64349052
57NME10.63950423
58TESK20.62196020
59MAPK130.58574464
60CDK70.58435015
61ATM0.56704056
62PLK10.56482133
63PRKCI0.55780277
64GRK60.55004011
65STK160.54552737
66FGFR10.52297911
67CLK10.51465744
68NUAK10.50613880
69CHEK20.49856696
70JAK10.48561288
71MOS0.47753195
72ADRBK10.47398507
73MST40.44530923
74AURKB0.43417268
75TGFBR20.42317457
76STK110.41346049
77FLT30.41315053
78GRK10.41041107
79MARK30.39958079
80SYK0.39828468
81GRK50.39271200
82CSNK1A10.37049699
83TEC0.37047257
84PRKCE0.34588594
85CASK0.34421565
86TAOK30.33372627
87STK38L0.33047771
88PRKCG0.31919044
89GSK3A0.31765879
90ROCK10.29546319
91DYRK1A0.27538905
92PRKCQ0.26787367
93SIK10.25976400
94NEK10.25309278
95PTK2B0.25263386
96PRKDC0.25208520
97NLK0.24719945
98DYRK1B0.24533192
99BRSK10.23889681
100STK30.23643854

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004305.51962686
2Non-homologous end-joining_Homo sapiens_hsa034504.13253057
3Homologous recombination_Homo sapiens_hsa034402.97561270
4Fanconi anemia pathway_Homo sapiens_hsa034602.94308444
5Propanoate metabolism_Homo sapiens_hsa006402.93506314
6Base excision repair_Homo sapiens_hsa034102.91776229
7Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.61049902
8Nucleotide excision repair_Homo sapiens_hsa034202.32517146
9DNA replication_Homo sapiens_hsa030302.30649155
10Basal transcription factors_Homo sapiens_hsa030221.94620143
11RNA transport_Homo sapiens_hsa030131.87569859
12Cysteine and methionine metabolism_Homo sapiens_hsa002701.87194447
13Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.83520333
14Caffeine metabolism_Homo sapiens_hsa002321.80528506
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.76722593
16Mismatch repair_Homo sapiens_hsa034301.76522941
17Sulfur metabolism_Homo sapiens_hsa009201.63304340
18Ribosome_Homo sapiens_hsa030101.53584485
19Dorso-ventral axis formation_Homo sapiens_hsa043201.52849652
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50228787
21Spliceosome_Homo sapiens_hsa030401.50170066
22RNA degradation_Homo sapiens_hsa030181.48370695
23Cell cycle_Homo sapiens_hsa041101.44071141
24TGF-beta signaling pathway_Homo sapiens_hsa043501.40401260
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.33188817
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.33059444
27RNA polymerase_Homo sapiens_hsa030201.31906161
28Legionellosis_Homo sapiens_hsa051341.29526720
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.28912716
30Oxidative phosphorylation_Homo sapiens_hsa001901.22601254
31Protein export_Homo sapiens_hsa030601.22002747
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.18938782
33mRNA surveillance pathway_Homo sapiens_hsa030151.18659196
34Selenocompound metabolism_Homo sapiens_hsa004501.14043833
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.13271111
36NOD-like receptor signaling pathway_Homo sapiens_hsa046211.08097347
37Parkinsons disease_Homo sapiens_hsa050121.07003763
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.03528777
39Phototransduction_Homo sapiens_hsa047441.03497894
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.00942889
41Proteasome_Homo sapiens_hsa030500.99668845
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.95650504
43Systemic lupus erythematosus_Homo sapiens_hsa053220.91547762
44Regulation of autophagy_Homo sapiens_hsa041400.90940355
45Olfactory transduction_Homo sapiens_hsa047400.89961850
46Alzheimers disease_Homo sapiens_hsa050100.89818179
47Cholinergic synapse_Homo sapiens_hsa047250.89397484
48Nitrogen metabolism_Homo sapiens_hsa009100.87798004
49Oocyte meiosis_Homo sapiens_hsa041140.83891295
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79067688
51Huntingtons disease_Homo sapiens_hsa050160.78710108
52Purine metabolism_Homo sapiens_hsa002300.78005537
53Pyrimidine metabolism_Homo sapiens_hsa002400.75080395
54Peroxisome_Homo sapiens_hsa041460.74682222
55Lysine degradation_Homo sapiens_hsa003100.74044922
56Chemical carcinogenesis_Homo sapiens_hsa052040.69432957
57Taste transduction_Homo sapiens_hsa047420.64916809
58Malaria_Homo sapiens_hsa051440.63565737
59Axon guidance_Homo sapiens_hsa043600.63535081
60Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63116142
61Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60987708
62Nicotine addiction_Homo sapiens_hsa050330.59955801
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59919612
64Alcoholism_Homo sapiens_hsa050340.58840476
65p53 signaling pathway_Homo sapiens_hsa041150.57891882
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53291205
67Wnt signaling pathway_Homo sapiens_hsa043100.52924095
68Tryptophan metabolism_Homo sapiens_hsa003800.52172520
69Collecting duct acid secretion_Homo sapiens_hsa049660.51873833
70Retinol metabolism_Homo sapiens_hsa008300.50726174
71ABC transporters_Homo sapiens_hsa020100.48041948
72African trypanosomiasis_Homo sapiens_hsa051430.47561177
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45257064
74Gastric acid secretion_Homo sapiens_hsa049710.45018800
75Apoptosis_Homo sapiens_hsa042100.43358032
76Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41222819
77FoxO signaling pathway_Homo sapiens_hsa040680.40011747
78Steroid biosynthesis_Homo sapiens_hsa001000.39163403
79Hedgehog signaling pathway_Homo sapiens_hsa043400.38850470
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38642689
81Primary immunodeficiency_Homo sapiens_hsa053400.37777848
82cAMP signaling pathway_Homo sapiens_hsa040240.36815435
83Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35982719
84Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.34469775
85Butanoate metabolism_Homo sapiens_hsa006500.34077221
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.32050679
87Colorectal cancer_Homo sapiens_hsa052100.31530742
88Estrogen signaling pathway_Homo sapiens_hsa049150.31008507
89Metabolic pathways_Homo sapiens_hsa011000.29743758
90Salivary secretion_Homo sapiens_hsa049700.29209072
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27268173
92Amphetamine addiction_Homo sapiens_hsa050310.26836878
93Notch signaling pathway_Homo sapiens_hsa043300.26199459
94Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.25981609
95Renin secretion_Homo sapiens_hsa049240.25775458
96Long-term depression_Homo sapiens_hsa047300.24101475
97Linoleic acid metabolism_Homo sapiens_hsa005910.23745658
98Viral carcinogenesis_Homo sapiens_hsa052030.23040622
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.21688923
100Insulin secretion_Homo sapiens_hsa049110.21021970

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »