RPL7P19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.54120652
2DNA deamination (GO:0045006)4.85381601
3behavioral response to nicotine (GO:0035095)4.84826717
4viral transcription (GO:0019083)4.49361448
5ATP synthesis coupled proton transport (GO:0015986)4.30944426
6energy coupled proton transport, down electrochemical gradient (GO:0015985)4.30944426
7translational termination (GO:0006415)4.30472131
8kynurenine metabolic process (GO:0070189)4.14005167
9maturation of SSU-rRNA (GO:0030490)4.08871533
10protein neddylation (GO:0045116)3.88818597
11indolalkylamine catabolic process (GO:0046218)3.85602711
12tryptophan catabolic process (GO:0006569)3.85602711
13indole-containing compound catabolic process (GO:0042436)3.85602711
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.85098522
15negative regulation of mast cell activation (GO:0033004)3.84253443
16translational elongation (GO:0006414)3.74331177
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.71842418
18mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.70995992
19rRNA catabolic process (GO:0016075)3.70290954
20response to pheromone (GO:0019236)3.68660144
21cotranslational protein targeting to membrane (GO:0006613)3.65632447
22protein targeting to ER (GO:0045047)3.62898567
23nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.52554530
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.45753223
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.45742812
26somite development (GO:0061053)3.42491430
27protein localization to endoplasmic reticulum (GO:0070972)3.41472485
28exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.38972173
29fucose catabolic process (GO:0019317)3.32301178
30L-fucose metabolic process (GO:0042354)3.32301178
31L-fucose catabolic process (GO:0042355)3.32301178
32tryptophan metabolic process (GO:0006568)3.31604396
33base-excision repair, AP site formation (GO:0006285)3.31018019
34indolalkylamine metabolic process (GO:0006586)3.28854141
35tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.28668703
36RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.28668703
37protein complex biogenesis (GO:0070271)3.25944412
38viral life cycle (GO:0019058)3.23628968
39regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.23347321
40electron transport chain (GO:0022900)3.19130971
41respiratory electron transport chain (GO:0022904)3.18321813
42preassembly of GPI anchor in ER membrane (GO:0016254)3.16579796
43ribosomal small subunit biogenesis (GO:0042274)3.11232220
44cellular protein complex disassembly (GO:0043624)3.09970304
45cytidine deamination (GO:0009972)3.09500810
46cytidine metabolic process (GO:0046087)3.09500810
47cytidine catabolic process (GO:0006216)3.09500810
48mitochondrial respiratory chain complex I assembly (GO:0032981)2.97249404
49NADH dehydrogenase complex assembly (GO:0010257)2.97249404
50mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.97249404
51cellular biogenic amine catabolic process (GO:0042402)2.96675822
52amine catabolic process (GO:0009310)2.96675822
53mitochondrial respiratory chain complex assembly (GO:0033108)2.94425220
54protein-cofactor linkage (GO:0018065)2.94000139
55pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.92807003
56nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.91590560
57ribosomal large subunit biogenesis (GO:0042273)2.84764399
58translational initiation (GO:0006413)2.84677606
59platelet dense granule organization (GO:0060155)2.83324120
60negative regulation of T cell differentiation in thymus (GO:0033085)2.81317086
61detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.80415733
62auditory receptor cell stereocilium organization (GO:0060088)2.79877698
63piRNA metabolic process (GO:0034587)2.77314175
64respiratory chain complex IV assembly (GO:0008535)2.76837321
65positive regulation of defense response to virus by host (GO:0002230)2.75938331
66regulation of cilium movement (GO:0003352)2.75338275
67meiotic chromosome segregation (GO:0045132)2.72884951
68pyrimidine ribonucleoside catabolic process (GO:0046133)2.72229502
69negative regulation of heart rate (GO:0010459)2.71948675
70GPI anchor metabolic process (GO:0006505)2.70934230
71hydrogen ion transmembrane transport (GO:1902600)2.70219623
72cytochrome complex assembly (GO:0017004)2.70133360
73mannosylation (GO:0097502)2.68102405
74proton transport (GO:0015992)2.68083514
75translation (GO:0006412)2.65192312
76hydrogen transport (GO:0006818)2.64437194
77RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.64268127
78axoneme assembly (GO:0035082)2.61570540
79water-soluble vitamin biosynthetic process (GO:0042364)2.59816463
80establishment of protein localization to mitochondrial membrane (GO:0090151)2.59100254
81protein complex disassembly (GO:0043241)2.55649824
82ATP biosynthetic process (GO:0006754)2.55415021
83pyrimidine nucleotide catabolic process (GO:0006244)2.53249306
84negative regulation of telomere maintenance (GO:0032205)2.50054976
85C-terminal protein lipidation (GO:0006501)2.49928516
86GPI anchor biosynthetic process (GO:0006506)2.49800498
87deoxyribonucleotide catabolic process (GO:0009264)2.49776292
88purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.48926022
89positive regulation of T cell apoptotic process (GO:0070234)2.48612542
90DNA demethylation (GO:0080111)2.48271338
91positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.47759548
92deoxyribose phosphate catabolic process (GO:0046386)2.47393573
93positive regulation of fatty acid transport (GO:2000193)2.47209204
94purine nucleoside triphosphate biosynthetic process (GO:0009145)2.46676335
95macromolecular complex disassembly (GO:0032984)2.46054346
96detection of light stimulus involved in visual perception (GO:0050908)2.46024078
97detection of light stimulus involved in sensory perception (GO:0050962)2.46024078
98positive regulation of prostaglandin secretion (GO:0032308)2.44144249
99regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.43398174
100mast cell activation involved in immune response (GO:0002279)2.41657484

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.03204649
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.44117764
3ZNF274_21170338_ChIP-Seq_K562_Hela3.25172676
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.11425187
5VDR_22108803_ChIP-Seq_LS180_Human3.06326500
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.51354993
7MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.33285252
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.30993585
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.27529507
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.13196354
11FLI1_27457419_Chip-Seq_LIVER_Mouse1.90632502
12IRF1_19129219_ChIP-ChIP_H3396_Human1.89312703
13VDR_23849224_ChIP-Seq_CD4+_Human1.88886684
14EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.84667507
15TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.79308665
16TP53_22573176_ChIP-Seq_HFKS_Human1.76939036
17EWS_26573619_Chip-Seq_HEK293_Human1.71808741
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.70838410
19RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.68000972
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.66942229
21MYC_18940864_ChIP-ChIP_HL60_Human1.66209069
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.61498048
23PCGF2_27294783_Chip-Seq_ESCs_Mouse1.57376943
24CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.56574056
25IGF1R_20145208_ChIP-Seq_DFB_Human1.55306486
26ETS1_20019798_ChIP-Seq_JURKAT_Human1.55016260
27FUS_26573619_Chip-Seq_HEK293_Human1.53924808
28GATA3_21878914_ChIP-Seq_MCF-7_Human1.50219963
29IRF8_22096565_ChIP-ChIP_GC-B_Human1.49829085
30GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.49231775
31FOXA1_25329375_ChIP-Seq_VCAP_Human1.48003058
32FOXA1_27270436_Chip-Seq_PROSTATE_Human1.48003058
33AR_20517297_ChIP-Seq_VCAP_Human1.47983402
34FOXP3_21729870_ChIP-Seq_TREG_Human1.45315034
35ER_23166858_ChIP-Seq_MCF-7_Human1.42258830
36PCGF2_27294783_Chip-Seq_NPCs_Mouse1.42103501
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41218634
38NANOG_20526341_ChIP-Seq_ESCs_Human1.40521486
39EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.39676430
40ZFP57_27257070_Chip-Seq_ESCs_Mouse1.39597020
41ETV2_25802403_ChIP-Seq_MESCs_Mouse1.39429290
42TAF2_19829295_ChIP-Seq_ESCs_Human1.35654592
43MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35622279
44BP1_19119308_ChIP-ChIP_Hs578T_Human1.34183571
45NOTCH1_21737748_ChIP-Seq_TLL_Human1.33964212
46GBX2_23144817_ChIP-Seq_PC3_Human1.33434097
47IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.31157888
48P300_19829295_ChIP-Seq_ESCs_Human1.30378691
49FOXH1_21741376_ChIP-Seq_EPCs_Human1.29353942
50GATA3_26560356_Chip-Seq_TH2_Human1.28973431
51PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.27976864
52LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.27933838
53ELK1_19687146_ChIP-ChIP_HELA_Human1.26707811
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.24497647
55RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.24477476
56AUTS2_25519132_ChIP-Seq_293T-REX_Human1.23969194
57CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23626716
58CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.22938563
59CBP_20019798_ChIP-Seq_JUKART_Human1.22766660
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.22766660
61TAF15_26573619_Chip-Seq_HEK293_Human1.20885149
62NANOG_19829295_ChIP-Seq_ESCs_Human1.19820455
63SOX2_19829295_ChIP-Seq_ESCs_Human1.19820455
64HOXB7_26014856_ChIP-Seq_BT474_Human1.18979494
65NCOR_22424771_ChIP-Seq_293T_Human1.18285277
66ERA_21632823_ChIP-Seq_H3396_Human1.15420258
67REST_21632747_ChIP-Seq_MESCs_Mouse1.15223087
68FOXA1_21572438_ChIP-Seq_LNCaP_Human1.14297243
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.14130895
70MYC_19829295_ChIP-Seq_ESCs_Human1.13586008
71TDRD3_21172665_ChIP-Seq_MCF-7_Human1.11738183
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.11221288
73P53_21459846_ChIP-Seq_SAOS-2_Human1.09326086
74ELF1_17652178_ChIP-ChIP_JURKAT_Human1.07396699
75SRF_21415370_ChIP-Seq_HL-1_Mouse1.06066608
76JARID2_20064375_ChIP-Seq_MESCs_Mouse1.03400147
77TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.03143759
78EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02663339
79E2F1_20622854_ChIP-Seq_HELA_Human1.00557008
80EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.00434042
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99042828
82FOXH1_21741376_ChIP-Seq_ESCs_Human0.98015472
83ERG_20517297_ChIP-Seq_VCAP_Human0.97410589
84KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97053020
85UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96958715
86IRF8_21731497_ChIP-ChIP_J774_Mouse0.96384494
87RNF2_27304074_Chip-Seq_NSC_Mouse0.95846338
88PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95626355
89GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95388386
90PRDM14_20953172_ChIP-Seq_ESCs_Human0.95092753
91NFE2_27457419_Chip-Seq_LIVER_Mouse0.94669941
92HTT_18923047_ChIP-ChIP_STHdh_Human0.93181801
93SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92592512
94TCF4_22108803_ChIP-Seq_LS180_Human0.92426746
95EZH2_27294783_Chip-Seq_ESCs_Mouse0.91959327
96P300_27268052_Chip-Seq_Bcells_Human0.91940414
97BCL6_27268052_Chip-Seq_Bcells_Human0.91447409
98FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.90782199
99CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.89343986
100GATA6_21074721_ChIP-Seq_CACO-2_Human0.89312389

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation3.84368202
2MP0006292_abnormal_olfactory_placode3.71772959
3MP0005646_abnormal_pituitary_gland2.59414760
4MP0005377_hearing/vestibular/ear_phenot2.47217292
5MP0003878_abnormal_ear_physiology2.47217292
6MP0005671_abnormal_response_to2.44388532
7MP0002102_abnormal_ear_morphology2.42038123
8MP0006072_abnormal_retinal_apoptosis2.42002269
9MP0003646_muscle_fatigue2.40524028
10MP0008877_abnormal_DNA_methylation2.37411214
11MP0003787_abnormal_imprinting2.26352975
12MP0001835_abnormal_antigen_presentation2.22449533
13MP0008872_abnormal_physiological_respon2.11345336
14MP0004885_abnormal_endolymph2.06100106
15MP0005551_abnormal_eye_electrophysiolog1.97524057
16MP0002138_abnormal_hepatobiliary_system1.84087646
17MP0004142_abnormal_muscle_tone1.80091293
18MP0001968_abnormal_touch/_nociception1.78778722
19MP0008875_abnormal_xenobiotic_pharmacok1.77846388
20MP0002876_abnormal_thyroid_physiology1.77171887
21MP0005645_abnormal_hypothalamus_physiol1.70983655
22MP0002163_abnormal_gland_morphology1.68406990
23MP0003122_maternal_imprinting1.62433720
24MP0001986_abnormal_taste_sensitivity1.61706386
25MP0003880_abnormal_central_pattern1.61195775
26MP0001485_abnormal_pinna_reflex1.55946190
27MP0002837_dystrophic_cardiac_calcinosis1.55580795
28MP0003011_delayed_dark_adaptation1.55148925
29MP0002653_abnormal_ependyma_morphology1.54715783
30MP0002234_abnormal_pharynx_morphology1.53432327
31MP0002272_abnormal_nervous_system1.49602536
32MP0002736_abnormal_nociception_after1.45867415
33MP0006276_abnormal_autonomic_nervous1.45398796
34MP0008789_abnormal_olfactory_epithelium1.45270814
35MP0009764_decreased_sensitivity_to1.43195313
36MP0009745_abnormal_behavioral_response1.33068867
37MP0005084_abnormal_gallbladder_morpholo1.32696721
38MP0004147_increased_porphyrin_level1.31468282
39MP0001970_abnormal_pain_threshold1.29308325
40MP0005253_abnormal_eye_physiology1.28746440
41MP0001800_abnormal_humoral_immune1.27686065
42MP0001293_anophthalmia1.27501201
43MP0000372_irregular_coat_pigmentation1.27157964
44MP0005075_abnormal_melanosome_morpholog1.26718274
45MP0000631_abnormal_neuroendocrine_gland1.23509875
46MP0008995_early_reproductive_senescence1.17224810
47MP0001905_abnormal_dopamine_level1.16365837
48MP0002733_abnormal_thermal_nociception1.15961830
49MP0008775_abnormal_heart_ventricle1.13132007
50MP0004145_abnormal_muscle_electrophysio1.09518475
51MP0003195_calcinosis1.08298169
52MP0001501_abnormal_sleep_pattern1.06384077
53MP0000427_abnormal_hair_cycle1.04873389
54MP0009785_altered_susceptibility_to1.04580614
55MP0004742_abnormal_vestibular_system1.03118538
56MP0002148_abnormal_hypersensitivity_rea1.02853185
57MP0001440_abnormal_grooming_behavior1.02272020
58MP0001984_abnormal_olfaction1.01970570
59MP0002723_abnormal_immune_serum1.01338043
60MP0000049_abnormal_middle_ear0.99396191
61MP0005389_reproductive_system_phenotype0.99004585
62MP0003866_abnormal_defecation0.97149644
63MP0001486_abnormal_startle_reflex0.96838342
64MP0000685_abnormal_immune_system0.95984365
65MP0001919_abnormal_reproductive_system0.95839968
66MP0005195_abnormal_posterior_eye0.94972606
67MP0003283_abnormal_digestive_organ0.94521213
68MP0005000_abnormal_immune_tolerance0.94045933
69MP0002557_abnormal_social/conspecific_i0.93907487
70MP0000230_abnormal_systemic_arterial0.93669512
71MP0003121_genomic_imprinting0.93317727
72MP0005085_abnormal_gallbladder_physiolo0.92238021
73MP0003879_abnormal_hair_cell0.91620203
74MP0003938_abnormal_ear_development0.91397955
75MP0000026_abnormal_inner_ear0.89876939
76MP0002572_abnormal_emotion/affect_behav0.89383632
77MP0002638_abnormal_pupillary_reflex0.87510199
78MP0004043_abnormal_pH_regulation0.86696991
79MP0005499_abnormal_olfactory_system0.85111326
80MP0005394_taste/olfaction_phenotype0.85111326
81MP0001963_abnormal_hearing_physiology0.84880318
82MP0001765_abnormal_ion_homeostasis0.84802294
83MP0005410_abnormal_fertilization0.82254747
84MP0002735_abnormal_chemical_nociception0.81519739
85MP0010386_abnormal_urinary_bladder0.79953419
86MP0001502_abnormal_circadian_rhythm0.79748992
87MP0005636_abnormal_mineral_homeostasis0.78097372
88MP0002095_abnormal_skin_pigmentation0.77477180
89MP0003638_abnormal_response/metabolism_0.76996798
90MP0005379_endocrine/exocrine_gland_phen0.76505683
91MP0001790_abnormal_immune_system0.76022517
92MP0005387_immune_system_phenotype0.76022517
93MP0002452_abnormal_antigen_presenting0.75514099
94MP0005423_abnormal_somatic_nervous0.74335874
95MP0001819_abnormal_immune_cell0.74185470
96MP0003252_abnormal_bile_duct0.73564353
97MP0002752_abnormal_somatic_nervous0.72908571
98MP0003724_increased_susceptibility_to0.72532678
99MP0002420_abnormal_adaptive_immunity0.72494472
100MP0003136_yellow_coat_color0.72284122

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)3.95530877
2Pancreatic fibrosis (HP:0100732)3.91551218
3Pancreatic cysts (HP:0001737)3.83944823
4Molar tooth sign on MRI (HP:0002419)3.74387123
5Abnormality of midbrain morphology (HP:0002418)3.74387123
6Congenital stationary night blindness (HP:0007642)3.73901451
7Acute necrotizing encephalopathy (HP:0006965)3.58615365
8Abnormal rod and cone electroretinograms (HP:0008323)3.49001331
9Type II lissencephaly (HP:0007260)3.47051919
10Mitochondrial inheritance (HP:0001427)3.40655471
11True hermaphroditism (HP:0010459)3.28066777
12Increased CSF lactate (HP:0002490)3.10579640
13Reticulocytopenia (HP:0001896)3.08662914
14Abnormal mitochondria in muscle tissue (HP:0008316)3.03499474
15Lipid accumulation in hepatocytes (HP:0006561)3.02914401
16Acute encephalopathy (HP:0006846)3.02674057
17Progressive macrocephaly (HP:0004481)2.98191153
18Nephronophthisis (HP:0000090)2.97343747
19Abolished electroretinogram (ERG) (HP:0000550)2.94974256
20Abnormality of cells of the erythroid lineage (HP:0012130)2.92481930
21IgG deficiency (HP:0004315)2.87565022
22Hepatocellular necrosis (HP:0001404)2.84805623
23Decreased central vision (HP:0007663)2.84000782
24Attenuation of retinal blood vessels (HP:0007843)2.80594380
25Increased hepatocellular lipid droplets (HP:0006565)2.80210524
26Elevated erythrocyte sedimentation rate (HP:0003565)2.74649876
27Absent/shortened dynein arms (HP:0200106)2.65701514
28Dynein arm defect of respiratory motile cilia (HP:0012255)2.65701514
29Cerebellar dysplasia (HP:0007033)2.64375764
30Abnormality of the renal medulla (HP:0100957)2.56461061
31Absent thumb (HP:0009777)2.55499607
32Hepatic necrosis (HP:0002605)2.53265074
33Optic disc pallor (HP:0000543)2.50138174
34Abnormality of the renal cortex (HP:0011035)2.47956113
35Medial flaring of the eyebrow (HP:0010747)2.47501547
363-Methylglutaconic aciduria (HP:0003535)2.46317571
37Cerebral edema (HP:0002181)2.46164545
38Polydipsia (HP:0001959)2.45242237
39Abnormal drinking behavior (HP:0030082)2.45242237
40Cystic liver disease (HP:0006706)2.40383249
41Congenital, generalized hypertrichosis (HP:0004540)2.38175551
42Abnormal number of erythroid precursors (HP:0012131)2.34514982
43Sclerocornea (HP:0000647)2.31351934
44Aplasia/Hypoplasia of the spleen (HP:0010451)2.30339918
45Asplenia (HP:0001746)2.28154308
46Increased serum lactate (HP:0002151)2.24793247
47Macrocytic anemia (HP:0001972)2.22137658
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.20074787
49Pendular nystagmus (HP:0012043)2.17293745
50Methylmalonic acidemia (HP:0002912)2.16806521
51Tubular atrophy (HP:0000092)2.16181887
52Abnormal biliary tract physiology (HP:0012439)2.11841293
53Bile duct proliferation (HP:0001408)2.11841293
54Renal Fanconi syndrome (HP:0001994)2.08519262
55Polyuria (HP:0000103)2.07212998
56Agitation (HP:0000713)2.06695045
57Stomatitis (HP:0010280)2.05112093
58Septo-optic dysplasia (HP:0100842)2.04376904
59Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.03881778
60Colon cancer (HP:0003003)2.02127590
61Pallor (HP:0000980)2.02079910
62Lactic acidosis (HP:0003128)2.00896991
63Supernumerary spleens (HP:0009799)2.00644700
64Stenosis of the external auditory canal (HP:0000402)2.00462022
65Increased intramyocellular lipid droplets (HP:0012240)1.99222379
66Rib fusion (HP:0000902)1.98840935
67Methylmalonic aciduria (HP:0012120)1.98018884
68Abnormal respiratory motile cilium morphology (HP:0005938)1.97634972
69Abnormal respiratory epithelium morphology (HP:0012253)1.97634972
70Increased IgM level (HP:0003496)1.97579924
71Type 2 muscle fiber atrophy (HP:0003554)1.96218871
72Exertional dyspnea (HP:0002875)1.96004361
73Abnormality of the prostate (HP:0008775)1.94614551
74Retinal dysplasia (HP:0007973)1.94569803
75Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.94510962
76Congenital hepatic fibrosis (HP:0002612)1.92385634
77Keratoconus (HP:0000563)1.91792366
78Increased corneal curvature (HP:0100692)1.91792366
79Anencephaly (HP:0002323)1.90819369
80Abnormality of the renal collecting system (HP:0004742)1.90432424
81Hypoplasia of the ulna (HP:0003022)1.89982391
82Postaxial foot polydactyly (HP:0001830)1.89407508
83Chronic bronchitis (HP:0004469)1.88079663
84Increased muscle lipid content (HP:0009058)1.87641053
85Abnormal respiratory motile cilium physiology (HP:0012261)1.87486649
86Constricted visual fields (HP:0001133)1.87025428
87Abnormality of B cell number (HP:0010975)1.86920467
88Lethargy (HP:0001254)1.86368428
89Thyroiditis (HP:0100646)1.86307536
90Aplasia/hypoplasia of the uterus (HP:0008684)1.86096194
91Chronic hepatic failure (HP:0100626)1.85384633
92Hypoproteinemia (HP:0003075)1.83871514
93Ketosis (HP:0001946)1.83868561
94Hypomagnesemia (HP:0002917)1.80960707
95Severe combined immunodeficiency (HP:0004430)1.79577574
96Decreased circulating renin level (HP:0003351)1.79513631
97Bony spicule pigmentary retinopathy (HP:0007737)1.77133601
98Growth hormone deficiency (HP:0000824)1.76192376
99Aplasia/Hypoplasia of the ulna (HP:0006495)1.74279059
100Hyperalaninemia (HP:0003348)1.73262861

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK3.58511563
2CDK193.29320849
3FRK3.24935499
4TLK13.23628418
5ZAK3.06250005
6WNK42.99527244
7TXK2.96005830
8TAOK32.84460956
9GRK12.43714252
10TRIM282.41994849
11ADRBK22.41720161
12NUAK12.39108292
13PINK12.38631686
14MAP4K22.19751091
15CAMKK21.65295764
16BMPR1B1.56527735
17DYRK21.51520486
18STK161.50026091
19OXSR11.43971865
20MAP3K121.43105664
21PIK3CA1.37766726
22KIT1.34061108
23KDR1.33487678
24STK391.30461298
25WNK31.24814964
26CAMKK11.21770861
27ITK1.19161972
28TEC1.18655035
29TIE11.15428690
30BLK1.12692997
31FES1.06936203
32IKBKB1.05076643
33MAP3K41.02676701
34SYK0.97297112
35DAPK20.96681874
36INSRR0.93462152
37VRK20.92455847
38ERBB30.89986104
39GRK60.88747677
40BMPR20.88123967
41VRK10.87630073
42PRKCQ0.87044334
43NME10.86811908
44PHKG20.85059001
45PHKG10.85059001
46PASK0.81832605
47ADRBK10.81645185
48CDK80.79943191
49MYLK0.77605558
50MAP4K10.77508564
51MUSK0.75499244
52PDK20.74432859
53TNK20.72569045
54PRKCE0.69970431
55LYN0.69649529
56RPS6KA50.69279870
57MAPK130.66940600
58EIF2AK30.64863801
59CAMK10.64782033
60BTK0.64492814
61CSF1R0.64405424
62PRKCG0.62335627
63DAPK30.60162326
64PLK40.59323215
65GRK70.56671779
66DAPK10.56383684
67PLK20.55028409
68RPS6KA40.54512780
69OBSCN0.53251169
70LCK0.53167636
71MST40.53137978
72FLT30.52460322
73MAPKAPK30.50689253
74PRKACA0.50315629
75ATR0.49790517
76TNIK0.49268609
77PRKCA0.48746445
78MAP2K70.48590288
79ABL10.46268456
80GRK50.46229682
81MAP2K60.45950234
82MAPK150.44742063
83STK110.44222551
84PIM10.44058453
85LRRK20.41928879
86PRKCI0.41333422
87WNK10.41117382
88AURKB0.39975837
89PRKCH0.39729971
90IGF1R0.39071853
91EPHA40.38565093
92JAK30.38148719
93EPHA30.37993530
94RPS6KA60.37252144
95MAP2K20.35422929
96CSNK1G20.35002550
97IKBKE0.34956397
98MARK30.34623309
99ILK0.34339344
100PRKCD0.33853464

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053103.88513649
2Ribosome_Homo sapiens_hsa030103.70388748
3Oxidative phosphorylation_Homo sapiens_hsa001903.08336905
4Intestinal immune network for IgA production_Homo sapiens_hsa046722.98426705
5Allograft rejection_Homo sapiens_hsa053302.95664688
6Autoimmune thyroid disease_Homo sapiens_hsa053202.80962908
7Graft-versus-host disease_Homo sapiens_hsa053322.61100465
8Parkinsons disease_Homo sapiens_hsa050122.50748852
9Type I diabetes mellitus_Homo sapiens_hsa049402.35085978
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.26384857
11Linoleic acid metabolism_Homo sapiens_hsa005912.12971157
12Proteasome_Homo sapiens_hsa030502.12227976
13Caffeine metabolism_Homo sapiens_hsa002322.03935305
14Primary immunodeficiency_Homo sapiens_hsa053401.94338586
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.88065113
16Phototransduction_Homo sapiens_hsa047441.80441892
17Cardiac muscle contraction_Homo sapiens_hsa042601.72020428
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.64765175
19RNA polymerase_Homo sapiens_hsa030201.59925206
20Alzheimers disease_Homo sapiens_hsa050101.58050294
21Protein export_Homo sapiens_hsa030601.57796081
22Antigen processing and presentation_Homo sapiens_hsa046121.55491291
23Huntingtons disease_Homo sapiens_hsa050161.51821193
24Propanoate metabolism_Homo sapiens_hsa006401.41730434
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.41612600
26RNA degradation_Homo sapiens_hsa030181.37469474
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36991969
28Sulfur relay system_Homo sapiens_hsa041221.36276448
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.33408542
30Rheumatoid arthritis_Homo sapiens_hsa053231.32407444
31Tryptophan metabolism_Homo sapiens_hsa003801.28542737
32Nitrogen metabolism_Homo sapiens_hsa009101.26826599
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.25225181
34Fanconi anemia pathway_Homo sapiens_hsa034601.21778301
35Homologous recombination_Homo sapiens_hsa034401.21613902
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.17093952
37Regulation of autophagy_Homo sapiens_hsa041401.16603635
38Ether lipid metabolism_Homo sapiens_hsa005651.14387305
39Arachidonic acid metabolism_Homo sapiens_hsa005901.11830632
40Staphylococcus aureus infection_Homo sapiens_hsa051501.11107475
41One carbon pool by folate_Homo sapiens_hsa006701.07266216
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.98421438
43Olfactory transduction_Homo sapiens_hsa047400.97064369
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.95899496
45Butanoate metabolism_Homo sapiens_hsa006500.94506759
46Peroxisome_Homo sapiens_hsa041460.92151761
47Hematopoietic cell lineage_Homo sapiens_hsa046400.90986863
48Nicotine addiction_Homo sapiens_hsa050330.84102517
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.83149853
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.80997971
51Chemical carcinogenesis_Homo sapiens_hsa052040.80767092
52Morphine addiction_Homo sapiens_hsa050320.79833493
53Viral myocarditis_Homo sapiens_hsa054160.77478166
54Mismatch repair_Homo sapiens_hsa034300.75392557
55Basal transcription factors_Homo sapiens_hsa030220.74062620
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.72525602
57Systemic lupus erythematosus_Homo sapiens_hsa053220.70715149
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.69161960
59Retinol metabolism_Homo sapiens_hsa008300.68302537
60Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67743823
61Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.67596159
62Pyrimidine metabolism_Homo sapiens_hsa002400.67558479
63Purine metabolism_Homo sapiens_hsa002300.66919275
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.65126631
65Fat digestion and absorption_Homo sapiens_hsa049750.64553616
66Collecting duct acid secretion_Homo sapiens_hsa049660.61571278
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60082955
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.59849008
69Taste transduction_Homo sapiens_hsa047420.59519658
70Cysteine and methionine metabolism_Homo sapiens_hsa002700.58962368
71Base excision repair_Homo sapiens_hsa034100.58410569
72Selenocompound metabolism_Homo sapiens_hsa004500.56936256
73Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.55830676
74Salivary secretion_Homo sapiens_hsa049700.55275560
75Sulfur metabolism_Homo sapiens_hsa009200.54081407
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.51277546
77Leishmaniasis_Homo sapiens_hsa051400.51183110
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.50823986
79NOD-like receptor signaling pathway_Homo sapiens_hsa046210.50568653
80Metabolic pathways_Homo sapiens_hsa011000.50535214
81Nucleotide excision repair_Homo sapiens_hsa034200.48645266
82Serotonergic synapse_Homo sapiens_hsa047260.48555418
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47432651
84Ovarian steroidogenesis_Homo sapiens_hsa049130.46697666
85Fatty acid degradation_Homo sapiens_hsa000710.42853707
86Pyruvate metabolism_Homo sapiens_hsa006200.41573318
87Circadian entrainment_Homo sapiens_hsa047130.41039655
88Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.38522364
89GABAergic synapse_Homo sapiens_hsa047270.37889836
90Glutamatergic synapse_Homo sapiens_hsa047240.35778270
91DNA replication_Homo sapiens_hsa030300.35708836
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.32044458
93Insulin secretion_Homo sapiens_hsa049110.31333439
94Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.30649172
95Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.30345570
96Glycerolipid metabolism_Homo sapiens_hsa005610.30171745
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26536820
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.22449441
99T cell receptor signaling pathway_Homo sapiens_hsa046600.21940059
100Hedgehog signaling pathway_Homo sapiens_hsa043400.21039984

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