

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.54120652 |
| 2 | DNA deamination (GO:0045006) | 4.85381601 |
| 3 | behavioral response to nicotine (GO:0035095) | 4.84826717 |
| 4 | viral transcription (GO:0019083) | 4.49361448 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 4.30944426 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.30944426 |
| 7 | translational termination (GO:0006415) | 4.30472131 |
| 8 | kynurenine metabolic process (GO:0070189) | 4.14005167 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 4.08871533 |
| 10 | protein neddylation (GO:0045116) | 3.88818597 |
| 11 | indolalkylamine catabolic process (GO:0046218) | 3.85602711 |
| 12 | tryptophan catabolic process (GO:0006569) | 3.85602711 |
| 13 | indole-containing compound catabolic process (GO:0042436) | 3.85602711 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.85098522 |
| 15 | negative regulation of mast cell activation (GO:0033004) | 3.84253443 |
| 16 | translational elongation (GO:0006414) | 3.74331177 |
| 17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.71842418 |
| 18 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.70995992 |
| 19 | rRNA catabolic process (GO:0016075) | 3.70290954 |
| 20 | response to pheromone (GO:0019236) | 3.68660144 |
| 21 | cotranslational protein targeting to membrane (GO:0006613) | 3.65632447 |
| 22 | protein targeting to ER (GO:0045047) | 3.62898567 |
| 23 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.52554530 |
| 24 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.45753223 |
| 25 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.45742812 |
| 26 | somite development (GO:0061053) | 3.42491430 |
| 27 | protein localization to endoplasmic reticulum (GO:0070972) | 3.41472485 |
| 28 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.38972173 |
| 29 | fucose catabolic process (GO:0019317) | 3.32301178 |
| 30 | L-fucose metabolic process (GO:0042354) | 3.32301178 |
| 31 | L-fucose catabolic process (GO:0042355) | 3.32301178 |
| 32 | tryptophan metabolic process (GO:0006568) | 3.31604396 |
| 33 | base-excision repair, AP site formation (GO:0006285) | 3.31018019 |
| 34 | indolalkylamine metabolic process (GO:0006586) | 3.28854141 |
| 35 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.28668703 |
| 36 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.28668703 |
| 37 | protein complex biogenesis (GO:0070271) | 3.25944412 |
| 38 | viral life cycle (GO:0019058) | 3.23628968 |
| 39 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.23347321 |
| 40 | electron transport chain (GO:0022900) | 3.19130971 |
| 41 | respiratory electron transport chain (GO:0022904) | 3.18321813 |
| 42 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.16579796 |
| 43 | ribosomal small subunit biogenesis (GO:0042274) | 3.11232220 |
| 44 | cellular protein complex disassembly (GO:0043624) | 3.09970304 |
| 45 | cytidine deamination (GO:0009972) | 3.09500810 |
| 46 | cytidine metabolic process (GO:0046087) | 3.09500810 |
| 47 | cytidine catabolic process (GO:0006216) | 3.09500810 |
| 48 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.97249404 |
| 49 | NADH dehydrogenase complex assembly (GO:0010257) | 2.97249404 |
| 50 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.97249404 |
| 51 | cellular biogenic amine catabolic process (GO:0042402) | 2.96675822 |
| 52 | amine catabolic process (GO:0009310) | 2.96675822 |
| 53 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.94425220 |
| 54 | protein-cofactor linkage (GO:0018065) | 2.94000139 |
| 55 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.92807003 |
| 56 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.91590560 |
| 57 | ribosomal large subunit biogenesis (GO:0042273) | 2.84764399 |
| 58 | translational initiation (GO:0006413) | 2.84677606 |
| 59 | platelet dense granule organization (GO:0060155) | 2.83324120 |
| 60 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.81317086 |
| 61 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.80415733 |
| 62 | auditory receptor cell stereocilium organization (GO:0060088) | 2.79877698 |
| 63 | piRNA metabolic process (GO:0034587) | 2.77314175 |
| 64 | respiratory chain complex IV assembly (GO:0008535) | 2.76837321 |
| 65 | positive regulation of defense response to virus by host (GO:0002230) | 2.75938331 |
| 66 | regulation of cilium movement (GO:0003352) | 2.75338275 |
| 67 | meiotic chromosome segregation (GO:0045132) | 2.72884951 |
| 68 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.72229502 |
| 69 | negative regulation of heart rate (GO:0010459) | 2.71948675 |
| 70 | GPI anchor metabolic process (GO:0006505) | 2.70934230 |
| 71 | hydrogen ion transmembrane transport (GO:1902600) | 2.70219623 |
| 72 | cytochrome complex assembly (GO:0017004) | 2.70133360 |
| 73 | mannosylation (GO:0097502) | 2.68102405 |
| 74 | proton transport (GO:0015992) | 2.68083514 |
| 75 | translation (GO:0006412) | 2.65192312 |
| 76 | hydrogen transport (GO:0006818) | 2.64437194 |
| 77 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.64268127 |
| 78 | axoneme assembly (GO:0035082) | 2.61570540 |
| 79 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.59816463 |
| 80 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.59100254 |
| 81 | protein complex disassembly (GO:0043241) | 2.55649824 |
| 82 | ATP biosynthetic process (GO:0006754) | 2.55415021 |
| 83 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.53249306 |
| 84 | negative regulation of telomere maintenance (GO:0032205) | 2.50054976 |
| 85 | C-terminal protein lipidation (GO:0006501) | 2.49928516 |
| 86 | GPI anchor biosynthetic process (GO:0006506) | 2.49800498 |
| 87 | deoxyribonucleotide catabolic process (GO:0009264) | 2.49776292 |
| 88 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.48926022 |
| 89 | positive regulation of T cell apoptotic process (GO:0070234) | 2.48612542 |
| 90 | DNA demethylation (GO:0080111) | 2.48271338 |
| 91 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.47759548 |
| 92 | deoxyribose phosphate catabolic process (GO:0046386) | 2.47393573 |
| 93 | positive regulation of fatty acid transport (GO:2000193) | 2.47209204 |
| 94 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.46676335 |
| 95 | macromolecular complex disassembly (GO:0032984) | 2.46054346 |
| 96 | detection of light stimulus involved in visual perception (GO:0050908) | 2.46024078 |
| 97 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.46024078 |
| 98 | positive regulation of prostaglandin secretion (GO:0032308) | 2.44144249 |
| 99 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.43398174 |
| 100 | mast cell activation involved in immune response (GO:0002279) | 2.41657484 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.03204649 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.44117764 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.25172676 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.11425187 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.06326500 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51354993 |
| 7 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.33285252 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.30993585 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.27529507 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.13196354 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.90632502 |
| 12 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.89312703 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.88886684 |
| 14 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.84667507 |
| 15 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.79308665 |
| 16 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.76939036 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.71808741 |
| 18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.70838410 |
| 19 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.68000972 |
| 20 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.66942229 |
| 21 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.66209069 |
| 22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61498048 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.57376943 |
| 24 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.56574056 |
| 25 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55306486 |
| 26 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55016260 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.53924808 |
| 28 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.50219963 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.49829085 |
| 30 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.49231775 |
| 31 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.48003058 |
| 32 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.48003058 |
| 33 | AR_20517297_ChIP-Seq_VCAP_Human | 1.47983402 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.45315034 |
| 35 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.42258830 |
| 36 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.42103501 |
| 37 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.41218634 |
| 38 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.40521486 |
| 39 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.39676430 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.39597020 |
| 41 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.39429290 |
| 42 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.35654592 |
| 43 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35622279 |
| 44 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.34183571 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.33964212 |
| 46 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.33434097 |
| 47 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.31157888 |
| 48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.30378691 |
| 49 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.29353942 |
| 50 | GATA3_26560356_Chip-Seq_TH2_Human | 1.28973431 |
| 51 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27976864 |
| 52 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27933838 |
| 53 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.26707811 |
| 54 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.24497647 |
| 55 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.24477476 |
| 56 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.23969194 |
| 57 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.23626716 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.22938563 |
| 59 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.22766660 |
| 60 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.22766660 |
| 61 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.20885149 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19820455 |
| 63 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19820455 |
| 64 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.18979494 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.18285277 |
| 66 | ERA_21632823_ChIP-Seq_H3396_Human | 1.15420258 |
| 67 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.15223087 |
| 68 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.14297243 |
| 69 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.14130895 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.13586008 |
| 71 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.11738183 |
| 72 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.11221288 |
| 73 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.09326086 |
| 74 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.07396699 |
| 75 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.06066608 |
| 76 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.03400147 |
| 77 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03143759 |
| 78 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.02663339 |
| 79 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.00557008 |
| 80 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.00434042 |
| 81 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.99042828 |
| 82 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.98015472 |
| 83 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.97410589 |
| 84 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97053020 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96958715 |
| 86 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.96384494 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.95846338 |
| 88 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95626355 |
| 89 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.95388386 |
| 90 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.95092753 |
| 91 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.94669941 |
| 92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.93181801 |
| 93 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92592512 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.92426746 |
| 95 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.91959327 |
| 96 | P300_27268052_Chip-Seq_Bcells_Human | 0.91940414 |
| 97 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.91447409 |
| 98 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90782199 |
| 99 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.89343986 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.89312389 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.84368202 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.71772959 |
| 3 | MP0005646_abnormal_pituitary_gland | 2.59414760 |
| 4 | MP0005377_hearing/vestibular/ear_phenot | 2.47217292 |
| 5 | MP0003878_abnormal_ear_physiology | 2.47217292 |
| 6 | MP0005671_abnormal_response_to | 2.44388532 |
| 7 | MP0002102_abnormal_ear_morphology | 2.42038123 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.42002269 |
| 9 | MP0003646_muscle_fatigue | 2.40524028 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.37411214 |
| 11 | MP0003787_abnormal_imprinting | 2.26352975 |
| 12 | MP0001835_abnormal_antigen_presentation | 2.22449533 |
| 13 | MP0008872_abnormal_physiological_respon | 2.11345336 |
| 14 | MP0004885_abnormal_endolymph | 2.06100106 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.97524057 |
| 16 | MP0002138_abnormal_hepatobiliary_system | 1.84087646 |
| 17 | MP0004142_abnormal_muscle_tone | 1.80091293 |
| 18 | MP0001968_abnormal_touch/_nociception | 1.78778722 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.77846388 |
| 20 | MP0002876_abnormal_thyroid_physiology | 1.77171887 |
| 21 | MP0005645_abnormal_hypothalamus_physiol | 1.70983655 |
| 22 | MP0002163_abnormal_gland_morphology | 1.68406990 |
| 23 | MP0003122_maternal_imprinting | 1.62433720 |
| 24 | MP0001986_abnormal_taste_sensitivity | 1.61706386 |
| 25 | MP0003880_abnormal_central_pattern | 1.61195775 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.55946190 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.55580795 |
| 28 | MP0003011_delayed_dark_adaptation | 1.55148925 |
| 29 | MP0002653_abnormal_ependyma_morphology | 1.54715783 |
| 30 | MP0002234_abnormal_pharynx_morphology | 1.53432327 |
| 31 | MP0002272_abnormal_nervous_system | 1.49602536 |
| 32 | MP0002736_abnormal_nociception_after | 1.45867415 |
| 33 | MP0006276_abnormal_autonomic_nervous | 1.45398796 |
| 34 | MP0008789_abnormal_olfactory_epithelium | 1.45270814 |
| 35 | MP0009764_decreased_sensitivity_to | 1.43195313 |
| 36 | MP0009745_abnormal_behavioral_response | 1.33068867 |
| 37 | MP0005084_abnormal_gallbladder_morpholo | 1.32696721 |
| 38 | MP0004147_increased_porphyrin_level | 1.31468282 |
| 39 | MP0001970_abnormal_pain_threshold | 1.29308325 |
| 40 | MP0005253_abnormal_eye_physiology | 1.28746440 |
| 41 | MP0001800_abnormal_humoral_immune | 1.27686065 |
| 42 | MP0001293_anophthalmia | 1.27501201 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.27157964 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.26718274 |
| 45 | MP0000631_abnormal_neuroendocrine_gland | 1.23509875 |
| 46 | MP0008995_early_reproductive_senescence | 1.17224810 |
| 47 | MP0001905_abnormal_dopamine_level | 1.16365837 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.15961830 |
| 49 | MP0008775_abnormal_heart_ventricle | 1.13132007 |
| 50 | MP0004145_abnormal_muscle_electrophysio | 1.09518475 |
| 51 | MP0003195_calcinosis | 1.08298169 |
| 52 | MP0001501_abnormal_sleep_pattern | 1.06384077 |
| 53 | MP0000427_abnormal_hair_cycle | 1.04873389 |
| 54 | MP0009785_altered_susceptibility_to | 1.04580614 |
| 55 | MP0004742_abnormal_vestibular_system | 1.03118538 |
| 56 | MP0002148_abnormal_hypersensitivity_rea | 1.02853185 |
| 57 | MP0001440_abnormal_grooming_behavior | 1.02272020 |
| 58 | MP0001984_abnormal_olfaction | 1.01970570 |
| 59 | MP0002723_abnormal_immune_serum | 1.01338043 |
| 60 | MP0000049_abnormal_middle_ear | 0.99396191 |
| 61 | MP0005389_reproductive_system_phenotype | 0.99004585 |
| 62 | MP0003866_abnormal_defecation | 0.97149644 |
| 63 | MP0001486_abnormal_startle_reflex | 0.96838342 |
| 64 | MP0000685_abnormal_immune_system | 0.95984365 |
| 65 | MP0001919_abnormal_reproductive_system | 0.95839968 |
| 66 | MP0005195_abnormal_posterior_eye | 0.94972606 |
| 67 | MP0003283_abnormal_digestive_organ | 0.94521213 |
| 68 | MP0005000_abnormal_immune_tolerance | 0.94045933 |
| 69 | MP0002557_abnormal_social/conspecific_i | 0.93907487 |
| 70 | MP0000230_abnormal_systemic_arterial | 0.93669512 |
| 71 | MP0003121_genomic_imprinting | 0.93317727 |
| 72 | MP0005085_abnormal_gallbladder_physiolo | 0.92238021 |
| 73 | MP0003879_abnormal_hair_cell | 0.91620203 |
| 74 | MP0003938_abnormal_ear_development | 0.91397955 |
| 75 | MP0000026_abnormal_inner_ear | 0.89876939 |
| 76 | MP0002572_abnormal_emotion/affect_behav | 0.89383632 |
| 77 | MP0002638_abnormal_pupillary_reflex | 0.87510199 |
| 78 | MP0004043_abnormal_pH_regulation | 0.86696991 |
| 79 | MP0005499_abnormal_olfactory_system | 0.85111326 |
| 80 | MP0005394_taste/olfaction_phenotype | 0.85111326 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.84880318 |
| 82 | MP0001765_abnormal_ion_homeostasis | 0.84802294 |
| 83 | MP0005410_abnormal_fertilization | 0.82254747 |
| 84 | MP0002735_abnormal_chemical_nociception | 0.81519739 |
| 85 | MP0010386_abnormal_urinary_bladder | 0.79953419 |
| 86 | MP0001502_abnormal_circadian_rhythm | 0.79748992 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.78097372 |
| 88 | MP0002095_abnormal_skin_pigmentation | 0.77477180 |
| 89 | MP0003638_abnormal_response/metabolism_ | 0.76996798 |
| 90 | MP0005379_endocrine/exocrine_gland_phen | 0.76505683 |
| 91 | MP0001790_abnormal_immune_system | 0.76022517 |
| 92 | MP0005387_immune_system_phenotype | 0.76022517 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.75514099 |
| 94 | MP0005423_abnormal_somatic_nervous | 0.74335874 |
| 95 | MP0001819_abnormal_immune_cell | 0.74185470 |
| 96 | MP0003252_abnormal_bile_duct | 0.73564353 |
| 97 | MP0002752_abnormal_somatic_nervous | 0.72908571 |
| 98 | MP0003724_increased_susceptibility_to | 0.72532678 |
| 99 | MP0002420_abnormal_adaptive_immunity | 0.72494472 |
| 100 | MP0003136_yellow_coat_color | 0.72284122 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.95530877 |
| 2 | Pancreatic fibrosis (HP:0100732) | 3.91551218 |
| 3 | Pancreatic cysts (HP:0001737) | 3.83944823 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 3.74387123 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 3.74387123 |
| 6 | Congenital stationary night blindness (HP:0007642) | 3.73901451 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.58615365 |
| 8 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.49001331 |
| 9 | Type II lissencephaly (HP:0007260) | 3.47051919 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.40655471 |
| 11 | True hermaphroditism (HP:0010459) | 3.28066777 |
| 12 | Increased CSF lactate (HP:0002490) | 3.10579640 |
| 13 | Reticulocytopenia (HP:0001896) | 3.08662914 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.03499474 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.02914401 |
| 16 | Acute encephalopathy (HP:0006846) | 3.02674057 |
| 17 | Progressive macrocephaly (HP:0004481) | 2.98191153 |
| 18 | Nephronophthisis (HP:0000090) | 2.97343747 |
| 19 | Abolished electroretinogram (ERG) (HP:0000550) | 2.94974256 |
| 20 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.92481930 |
| 21 | IgG deficiency (HP:0004315) | 2.87565022 |
| 22 | Hepatocellular necrosis (HP:0001404) | 2.84805623 |
| 23 | Decreased central vision (HP:0007663) | 2.84000782 |
| 24 | Attenuation of retinal blood vessels (HP:0007843) | 2.80594380 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.80210524 |
| 26 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.74649876 |
| 27 | Absent/shortened dynein arms (HP:0200106) | 2.65701514 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.65701514 |
| 29 | Cerebellar dysplasia (HP:0007033) | 2.64375764 |
| 30 | Abnormality of the renal medulla (HP:0100957) | 2.56461061 |
| 31 | Absent thumb (HP:0009777) | 2.55499607 |
| 32 | Hepatic necrosis (HP:0002605) | 2.53265074 |
| 33 | Optic disc pallor (HP:0000543) | 2.50138174 |
| 34 | Abnormality of the renal cortex (HP:0011035) | 2.47956113 |
| 35 | Medial flaring of the eyebrow (HP:0010747) | 2.47501547 |
| 36 | 3-Methylglutaconic aciduria (HP:0003535) | 2.46317571 |
| 37 | Cerebral edema (HP:0002181) | 2.46164545 |
| 38 | Polydipsia (HP:0001959) | 2.45242237 |
| 39 | Abnormal drinking behavior (HP:0030082) | 2.45242237 |
| 40 | Cystic liver disease (HP:0006706) | 2.40383249 |
| 41 | Congenital, generalized hypertrichosis (HP:0004540) | 2.38175551 |
| 42 | Abnormal number of erythroid precursors (HP:0012131) | 2.34514982 |
| 43 | Sclerocornea (HP:0000647) | 2.31351934 |
| 44 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.30339918 |
| 45 | Asplenia (HP:0001746) | 2.28154308 |
| 46 | Increased serum lactate (HP:0002151) | 2.24793247 |
| 47 | Macrocytic anemia (HP:0001972) | 2.22137658 |
| 48 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20074787 |
| 49 | Pendular nystagmus (HP:0012043) | 2.17293745 |
| 50 | Methylmalonic acidemia (HP:0002912) | 2.16806521 |
| 51 | Tubular atrophy (HP:0000092) | 2.16181887 |
| 52 | Abnormal biliary tract physiology (HP:0012439) | 2.11841293 |
| 53 | Bile duct proliferation (HP:0001408) | 2.11841293 |
| 54 | Renal Fanconi syndrome (HP:0001994) | 2.08519262 |
| 55 | Polyuria (HP:0000103) | 2.07212998 |
| 56 | Agitation (HP:0000713) | 2.06695045 |
| 57 | Stomatitis (HP:0010280) | 2.05112093 |
| 58 | Septo-optic dysplasia (HP:0100842) | 2.04376904 |
| 59 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.03881778 |
| 60 | Colon cancer (HP:0003003) | 2.02127590 |
| 61 | Pallor (HP:0000980) | 2.02079910 |
| 62 | Lactic acidosis (HP:0003128) | 2.00896991 |
| 63 | Supernumerary spleens (HP:0009799) | 2.00644700 |
| 64 | Stenosis of the external auditory canal (HP:0000402) | 2.00462022 |
| 65 | Increased intramyocellular lipid droplets (HP:0012240) | 1.99222379 |
| 66 | Rib fusion (HP:0000902) | 1.98840935 |
| 67 | Methylmalonic aciduria (HP:0012120) | 1.98018884 |
| 68 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.97634972 |
| 69 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.97634972 |
| 70 | Increased IgM level (HP:0003496) | 1.97579924 |
| 71 | Type 2 muscle fiber atrophy (HP:0003554) | 1.96218871 |
| 72 | Exertional dyspnea (HP:0002875) | 1.96004361 |
| 73 | Abnormality of the prostate (HP:0008775) | 1.94614551 |
| 74 | Retinal dysplasia (HP:0007973) | 1.94569803 |
| 75 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.94510962 |
| 76 | Congenital hepatic fibrosis (HP:0002612) | 1.92385634 |
| 77 | Keratoconus (HP:0000563) | 1.91792366 |
| 78 | Increased corneal curvature (HP:0100692) | 1.91792366 |
| 79 | Anencephaly (HP:0002323) | 1.90819369 |
| 80 | Abnormality of the renal collecting system (HP:0004742) | 1.90432424 |
| 81 | Hypoplasia of the ulna (HP:0003022) | 1.89982391 |
| 82 | Postaxial foot polydactyly (HP:0001830) | 1.89407508 |
| 83 | Chronic bronchitis (HP:0004469) | 1.88079663 |
| 84 | Increased muscle lipid content (HP:0009058) | 1.87641053 |
| 85 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.87486649 |
| 86 | Constricted visual fields (HP:0001133) | 1.87025428 |
| 87 | Abnormality of B cell number (HP:0010975) | 1.86920467 |
| 88 | Lethargy (HP:0001254) | 1.86368428 |
| 89 | Thyroiditis (HP:0100646) | 1.86307536 |
| 90 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.86096194 |
| 91 | Chronic hepatic failure (HP:0100626) | 1.85384633 |
| 92 | Hypoproteinemia (HP:0003075) | 1.83871514 |
| 93 | Ketosis (HP:0001946) | 1.83868561 |
| 94 | Hypomagnesemia (HP:0002917) | 1.80960707 |
| 95 | Severe combined immunodeficiency (HP:0004430) | 1.79577574 |
| 96 | Decreased circulating renin level (HP:0003351) | 1.79513631 |
| 97 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.77133601 |
| 98 | Growth hormone deficiency (HP:0000824) | 1.76192376 |
| 99 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.74279059 |
| 100 | Hyperalaninemia (HP:0003348) | 1.73262861 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 3.58511563 |
| 2 | CDK19 | 3.29320849 |
| 3 | FRK | 3.24935499 |
| 4 | TLK1 | 3.23628418 |
| 5 | ZAK | 3.06250005 |
| 6 | WNK4 | 2.99527244 |
| 7 | TXK | 2.96005830 |
| 8 | TAOK3 | 2.84460956 |
| 9 | GRK1 | 2.43714252 |
| 10 | TRIM28 | 2.41994849 |
| 11 | ADRBK2 | 2.41720161 |
| 12 | NUAK1 | 2.39108292 |
| 13 | PINK1 | 2.38631686 |
| 14 | MAP4K2 | 2.19751091 |
| 15 | CAMKK2 | 1.65295764 |
| 16 | BMPR1B | 1.56527735 |
| 17 | DYRK2 | 1.51520486 |
| 18 | STK16 | 1.50026091 |
| 19 | OXSR1 | 1.43971865 |
| 20 | MAP3K12 | 1.43105664 |
| 21 | PIK3CA | 1.37766726 |
| 22 | KIT | 1.34061108 |
| 23 | KDR | 1.33487678 |
| 24 | STK39 | 1.30461298 |
| 25 | WNK3 | 1.24814964 |
| 26 | CAMKK1 | 1.21770861 |
| 27 | ITK | 1.19161972 |
| 28 | TEC | 1.18655035 |
| 29 | TIE1 | 1.15428690 |
| 30 | BLK | 1.12692997 |
| 31 | FES | 1.06936203 |
| 32 | IKBKB | 1.05076643 |
| 33 | MAP3K4 | 1.02676701 |
| 34 | SYK | 0.97297112 |
| 35 | DAPK2 | 0.96681874 |
| 36 | INSRR | 0.93462152 |
| 37 | VRK2 | 0.92455847 |
| 38 | ERBB3 | 0.89986104 |
| 39 | GRK6 | 0.88747677 |
| 40 | BMPR2 | 0.88123967 |
| 41 | VRK1 | 0.87630073 |
| 42 | PRKCQ | 0.87044334 |
| 43 | NME1 | 0.86811908 |
| 44 | PHKG2 | 0.85059001 |
| 45 | PHKG1 | 0.85059001 |
| 46 | PASK | 0.81832605 |
| 47 | ADRBK1 | 0.81645185 |
| 48 | CDK8 | 0.79943191 |
| 49 | MYLK | 0.77605558 |
| 50 | MAP4K1 | 0.77508564 |
| 51 | MUSK | 0.75499244 |
| 52 | PDK2 | 0.74432859 |
| 53 | TNK2 | 0.72569045 |
| 54 | PRKCE | 0.69970431 |
| 55 | LYN | 0.69649529 |
| 56 | RPS6KA5 | 0.69279870 |
| 57 | MAPK13 | 0.66940600 |
| 58 | EIF2AK3 | 0.64863801 |
| 59 | CAMK1 | 0.64782033 |
| 60 | BTK | 0.64492814 |
| 61 | CSF1R | 0.64405424 |
| 62 | PRKCG | 0.62335627 |
| 63 | DAPK3 | 0.60162326 |
| 64 | PLK4 | 0.59323215 |
| 65 | GRK7 | 0.56671779 |
| 66 | DAPK1 | 0.56383684 |
| 67 | PLK2 | 0.55028409 |
| 68 | RPS6KA4 | 0.54512780 |
| 69 | OBSCN | 0.53251169 |
| 70 | LCK | 0.53167636 |
| 71 | MST4 | 0.53137978 |
| 72 | FLT3 | 0.52460322 |
| 73 | MAPKAPK3 | 0.50689253 |
| 74 | PRKACA | 0.50315629 |
| 75 | ATR | 0.49790517 |
| 76 | TNIK | 0.49268609 |
| 77 | PRKCA | 0.48746445 |
| 78 | MAP2K7 | 0.48590288 |
| 79 | ABL1 | 0.46268456 |
| 80 | GRK5 | 0.46229682 |
| 81 | MAP2K6 | 0.45950234 |
| 82 | MAPK15 | 0.44742063 |
| 83 | STK11 | 0.44222551 |
| 84 | PIM1 | 0.44058453 |
| 85 | LRRK2 | 0.41928879 |
| 86 | PRKCI | 0.41333422 |
| 87 | WNK1 | 0.41117382 |
| 88 | AURKB | 0.39975837 |
| 89 | PRKCH | 0.39729971 |
| 90 | IGF1R | 0.39071853 |
| 91 | EPHA4 | 0.38565093 |
| 92 | JAK3 | 0.38148719 |
| 93 | EPHA3 | 0.37993530 |
| 94 | RPS6KA6 | 0.37252144 |
| 95 | MAP2K2 | 0.35422929 |
| 96 | CSNK1G2 | 0.35002550 |
| 97 | IKBKE | 0.34956397 |
| 98 | MARK3 | 0.34623309 |
| 99 | ILK | 0.34339344 |
| 100 | PRKCD | 0.33853464 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.88513649 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.70388748 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.08336905 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.98426705 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.95664688 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.80962908 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.61100465 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50748852 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.35085978 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.26384857 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.12971157 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 2.12227976 |
| 13 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.03935305 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.94338586 |
| 15 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.88065113 |
| 16 | Phototransduction_Homo sapiens_hsa04744 | 1.80441892 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.72020428 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.64765175 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.59925206 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58050294 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.57796081 |
| 22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.55491291 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.51821193 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41730434 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.41612600 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.37469474 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.36991969 |
| 28 | Sulfur relay system_Homo sapiens_hsa04122 | 1.36276448 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.33408542 |
| 30 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.32407444 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.28542737 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.26826599 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25225181 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.21778301 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 1.21613902 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.17093952 |
| 37 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.16603635 |
| 38 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.14387305 |
| 39 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.11830632 |
| 40 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.11107475 |
| 41 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.07266216 |
| 42 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.98421438 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 0.97064369 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.95899496 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.94506759 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.92151761 |
| 47 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90986863 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 0.84102517 |
| 49 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.83149853 |
| 50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.80997971 |
| 51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80767092 |
| 52 | Morphine addiction_Homo sapiens_hsa05032 | 0.79833493 |
| 53 | Viral myocarditis_Homo sapiens_hsa05416 | 0.77478166 |
| 54 | Mismatch repair_Homo sapiens_hsa03430 | 0.75392557 |
| 55 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74062620 |
| 56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.72525602 |
| 57 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.70715149 |
| 58 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69161960 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68302537 |
| 60 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.67743823 |
| 61 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.67596159 |
| 62 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67558479 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.66919275 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65126631 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.64553616 |
| 66 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61571278 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.60082955 |
| 68 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.59849008 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.59519658 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.58962368 |
| 71 | Base excision repair_Homo sapiens_hsa03410 | 0.58410569 |
| 72 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56936256 |
| 73 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.55830676 |
| 74 | Salivary secretion_Homo sapiens_hsa04970 | 0.55275560 |
| 75 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.54081407 |
| 76 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.51277546 |
| 77 | Leishmaniasis_Homo sapiens_hsa05140 | 0.51183110 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50823986 |
| 79 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.50568653 |
| 80 | Metabolic pathways_Homo sapiens_hsa01100 | 0.50535214 |
| 81 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.48645266 |
| 82 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.48555418 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.47432651 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46697666 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42853707 |
| 86 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.41573318 |
| 87 | Circadian entrainment_Homo sapiens_hsa04713 | 0.41039655 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.38522364 |
| 89 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37889836 |
| 90 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.35778270 |
| 91 | DNA replication_Homo sapiens_hsa03030 | 0.35708836 |
| 92 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.32044458 |
| 93 | Insulin secretion_Homo sapiens_hsa04911 | 0.31333439 |
| 94 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.30649172 |
| 95 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.30345570 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.30171745 |
| 97 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.26536820 |
| 98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22449441 |
| 99 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.21940059 |
| 100 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.21039984 |

