

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 4.68397504 |
| 2 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.21663879 |
| 3 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.08292453 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.02238587 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 4.02238587 |
| 6 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.00456156 |
| 7 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.00456156 |
| 8 | rRNA modification (GO:0000154) | 3.99070537 |
| 9 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.97380110 |
| 10 | ribosomal small subunit assembly (GO:0000028) | 3.92499849 |
| 11 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.73703371 |
| 12 | protein neddylation (GO:0045116) | 3.72082343 |
| 13 | maturation of 5.8S rRNA (GO:0000460) | 3.70408835 |
| 14 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.60675300 |
| 15 | termination of RNA polymerase III transcription (GO:0006386) | 3.60675300 |
| 16 | respiratory chain complex IV assembly (GO:0008535) | 3.60521118 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.60490411 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.57840865 |
| 19 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.56646257 |
| 20 | proteasome assembly (GO:0043248) | 3.53286462 |
| 21 | behavioral response to nicotine (GO:0035095) | 3.51577416 |
| 22 | fucose catabolic process (GO:0019317) | 3.50894452 |
| 23 | L-fucose metabolic process (GO:0042354) | 3.50894452 |
| 24 | L-fucose catabolic process (GO:0042355) | 3.50894452 |
| 25 | ribosomal large subunit biogenesis (GO:0042273) | 3.45681063 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.38802792 |
| 27 | chaperone-mediated protein transport (GO:0072321) | 3.38542752 |
| 28 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.37186491 |
| 29 | DNA replication checkpoint (GO:0000076) | 3.30016203 |
| 30 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.28727215 |
| 31 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.26417444 |
| 32 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.26417444 |
| 33 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.26417444 |
| 34 | cytochrome complex assembly (GO:0017004) | 3.26406794 |
| 35 | DNA double-strand break processing (GO:0000729) | 3.25851794 |
| 36 | negative regulation of telomere maintenance (GO:0032205) | 3.24911620 |
| 37 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.24420142 |
| 38 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.22532771 |
| 39 | negative regulation of ligase activity (GO:0051352) | 3.22532771 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.21042888 |
| 41 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.21042888 |
| 42 | pseudouridine synthesis (GO:0001522) | 3.19830240 |
| 43 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.16955376 |
| 44 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.16955376 |
| 45 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.16601338 |
| 46 | rRNA methylation (GO:0031167) | 3.16054476 |
| 47 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.14468892 |
| 48 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.14468892 |
| 49 | isotype switching (GO:0045190) | 3.14468892 |
| 50 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.14197829 |
| 51 | cullin deneddylation (GO:0010388) | 3.11743898 |
| 52 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.08440322 |
| 53 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.08440322 |
| 54 | protein complex biogenesis (GO:0070271) | 3.08347749 |
| 55 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.04102228 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.99612133 |
| 57 | kynurenine metabolic process (GO:0070189) | 2.98674701 |
| 58 | protein deneddylation (GO:0000338) | 2.98280446 |
| 59 | tryptophan catabolic process (GO:0006569) | 2.95812529 |
| 60 | indole-containing compound catabolic process (GO:0042436) | 2.95812529 |
| 61 | indolalkylamine catabolic process (GO:0046218) | 2.95812529 |
| 62 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.92030869 |
| 63 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.92030869 |
| 64 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.91494120 |
| 65 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.91494120 |
| 66 | NADH dehydrogenase complex assembly (GO:0010257) | 2.91494120 |
| 67 | maturation of SSU-rRNA (GO:0030490) | 2.91412338 |
| 68 | nucleobase biosynthetic process (GO:0046112) | 2.90255650 |
| 69 | chromatin remodeling at centromere (GO:0031055) | 2.89397392 |
| 70 | aldehyde catabolic process (GO:0046185) | 2.86849262 |
| 71 | piRNA metabolic process (GO:0034587) | 2.86803850 |
| 72 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.86466494 |
| 73 | tRNA processing (GO:0008033) | 2.85817005 |
| 74 | branched-chain amino acid catabolic process (GO:0009083) | 2.85807034 |
| 75 | rRNA processing (GO:0006364) | 2.82824776 |
| 76 | rRNA metabolic process (GO:0016072) | 2.80347591 |
| 77 | negative regulation of B cell apoptotic process (GO:0002903) | 2.73808643 |
| 78 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.72803574 |
| 79 | purine nucleobase biosynthetic process (GO:0009113) | 2.70758431 |
| 80 | organelle disassembly (GO:1903008) | 2.68967235 |
| 81 | tRNA metabolic process (GO:0006399) | 2.68839785 |
| 82 | electron transport chain (GO:0022900) | 2.65773866 |
| 83 | regulation of helicase activity (GO:0051095) | 2.63085507 |
| 84 | translation (GO:0006412) | 2.63058886 |
| 85 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.62434960 |
| 86 | GTP biosynthetic process (GO:0006183) | 2.61550800 |
| 87 | positive regulation of prostaglandin secretion (GO:0032308) | 2.60979321 |
| 88 | mitochondrial RNA metabolic process (GO:0000959) | 2.60930842 |
| 89 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.60921439 |
| 90 | respiratory electron transport chain (GO:0022904) | 2.60654530 |
| 91 | response to pheromone (GO:0019236) | 2.60465978 |
| 92 | DNA strand renaturation (GO:0000733) | 2.58936086 |
| 93 | regulation of immunoglobulin secretion (GO:0051023) | 2.58219260 |
| 94 | replication fork processing (GO:0031297) | 2.57077517 |
| 95 | positive regulation of ligase activity (GO:0051351) | 2.56835833 |
| 96 | protein-cofactor linkage (GO:0018065) | 2.55855325 |
| 97 | cellular component biogenesis (GO:0044085) | 2.55326955 |
| 98 | ubiquinone biosynthetic process (GO:0006744) | 2.54400138 |
| 99 | tryptophan metabolic process (GO:0006568) | 2.54161233 |
| 100 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.52345894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.87422825 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.29753222 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83957329 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.47165515 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.04858205 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01878877 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95985778 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.93767595 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.88061008 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.65702196 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65014513 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.64220444 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.46813217 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.44477018 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38361962 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.29028936 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.23283494 |
| 18 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.23042825 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.19249301 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11972728 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.05856081 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.02611018 |
| 23 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.98198527 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.97610219 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.90886629 |
| 26 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.82513732 |
| 27 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.81523210 |
| 28 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.79339675 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.77786476 |
| 30 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.76272016 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.70948569 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.70054511 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.68497805 |
| 34 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.66998431 |
| 35 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.66640160 |
| 36 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.55450425 |
| 37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.53470628 |
| 38 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.50831494 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49372046 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47664702 |
| 41 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.47304850 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.44581528 |
| 43 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44063398 |
| 44 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.43585731 |
| 45 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.39568049 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.37313077 |
| 47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34409151 |
| 48 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.31803684 |
| 49 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.31803684 |
| 50 | P300_19829295_ChIP-Seq_ESCs_Human | 1.30478877 |
| 51 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30323954 |
| 52 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.29104721 |
| 53 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.21466475 |
| 54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.20606162 |
| 55 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.20512179 |
| 56 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19073665 |
| 57 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.17980327 |
| 58 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.17950392 |
| 59 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.17950392 |
| 60 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.15880834 |
| 61 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.15055563 |
| 62 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14365946 |
| 63 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.14158418 |
| 64 | AR_20517297_ChIP-Seq_VCAP_Human | 1.13590803 |
| 65 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.13109778 |
| 66 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.13038591 |
| 67 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.12653463 |
| 68 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.12626246 |
| 69 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.11921853 |
| 70 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.10932790 |
| 71 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.10925343 |
| 72 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.10557595 |
| 73 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.09078151 |
| 74 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.07612512 |
| 75 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.04752745 |
| 76 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.02667171 |
| 77 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.02667171 |
| 78 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01885783 |
| 79 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.01301763 |
| 80 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01031631 |
| 81 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.98933357 |
| 82 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.98139344 |
| 83 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.96585404 |
| 84 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.95884316 |
| 85 | GATA3_26560356_Chip-Seq_TH2_Human | 0.95148373 |
| 86 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93858935 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.93611680 |
| 88 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93451681 |
| 89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.93141282 |
| 90 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.92208206 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.90303624 |
| 92 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.88816543 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.88783072 |
| 94 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.88452307 |
| 95 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.87460318 |
| 96 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.86859576 |
| 97 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86575281 |
| 98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.85041639 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.84523065 |
| 100 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.83590270 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.62786801 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.53800241 |
| 3 | MP0008058_abnormal_DNA_repair | 2.92742452 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 2.90899891 |
| 5 | MP0002138_abnormal_hepatobiliary_system | 2.86804334 |
| 6 | MP0005646_abnormal_pituitary_gland | 2.69256358 |
| 7 | MP0002102_abnormal_ear_morphology | 2.48812341 |
| 8 | MP0008872_abnormal_physiological_respon | 2.43513035 |
| 9 | MP0009379_abnormal_foot_pigmentation | 2.42911580 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.41539030 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.21896001 |
| 12 | MP0003718_maternal_effect | 2.19520620 |
| 13 | MP0001835_abnormal_antigen_presentation | 2.04362562 |
| 14 | MP0010094_abnormal_chromosome_stability | 2.03114901 |
| 15 | MP0002736_abnormal_nociception_after | 2.00490083 |
| 16 | MP0001986_abnormal_taste_sensitivity | 1.87798188 |
| 17 | MP0001968_abnormal_touch/_nociception | 1.85294088 |
| 18 | MP0003787_abnormal_imprinting | 1.82268617 |
| 19 | MP0006072_abnormal_retinal_apoptosis | 1.81833871 |
| 20 | MP0003646_muscle_fatigue | 1.80606779 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.75425046 |
| 22 | MP0003786_premature_aging | 1.75088067 |
| 23 | MP0001293_anophthalmia | 1.73739984 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.71777314 |
| 25 | MP0008007_abnormal_cellular_replicative | 1.70559459 |
| 26 | MP0004147_increased_porphyrin_level | 1.67979419 |
| 27 | MP0005671_abnormal_response_to | 1.60509469 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.58674924 |
| 29 | MP0008789_abnormal_olfactory_epithelium | 1.57425780 |
| 30 | MP0000372_irregular_coat_pigmentation | 1.56439418 |
| 31 | MP0005075_abnormal_melanosome_morpholog | 1.52650896 |
| 32 | MP0002938_white_spotting | 1.46291459 |
| 33 | MP0006036_abnormal_mitochondrial_physio | 1.45934220 |
| 34 | MP0002148_abnormal_hypersensitivity_rea | 1.41734938 |
| 35 | MP0004957_abnormal_blastocyst_morpholog | 1.35771850 |
| 36 | MP0002006_tumorigenesis | 1.34588899 |
| 37 | MP0001485_abnormal_pinna_reflex | 1.30595760 |
| 38 | MP0003011_delayed_dark_adaptation | 1.30419549 |
| 39 | MP0009764_decreased_sensitivity_to | 1.27873603 |
| 40 | MP0003111_abnormal_nucleus_morphology | 1.27700520 |
| 41 | MP0006035_abnormal_mitochondrial_morpho | 1.23018555 |
| 42 | MP0000685_abnormal_immune_system | 1.22653200 |
| 43 | MP0002254_reproductive_system_inflammat | 1.21716668 |
| 44 | MP0003195_calcinosis | 1.20030920 |
| 45 | MP0002272_abnormal_nervous_system | 1.17779430 |
| 46 | MP0000613_abnormal_salivary_gland | 1.17008243 |
| 47 | MP0004885_abnormal_endolymph | 1.11565947 |
| 48 | MP0003186_abnormal_redox_activity | 1.10659490 |
| 49 | MP0004133_heterotaxia | 1.09787018 |
| 50 | MP0001984_abnormal_olfaction | 1.08309832 |
| 51 | MP0005084_abnormal_gallbladder_morpholo | 1.07285851 |
| 52 | MP0003121_genomic_imprinting | 1.05735504 |
| 53 | MP0005085_abnormal_gallbladder_physiolo | 1.05254801 |
| 54 | MP0003136_yellow_coat_color | 1.04152833 |
| 55 | MP0002876_abnormal_thyroid_physiology | 1.01317895 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.00287087 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 0.99886694 |
| 58 | MP0003878_abnormal_ear_physiology | 0.99886694 |
| 59 | MP0005332_abnormal_amino_acid | 0.98615801 |
| 60 | MP0004019_abnormal_vitamin_homeostasis | 0.94013042 |
| 61 | MP0001800_abnormal_humoral_immune | 0.93233734 |
| 62 | MP0005387_immune_system_phenotype | 0.91071928 |
| 63 | MP0001790_abnormal_immune_system | 0.91071928 |
| 64 | MP0005253_abnormal_eye_physiology | 0.90557013 |
| 65 | MP0008775_abnormal_heart_ventricle | 0.90003763 |
| 66 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89703755 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 0.89621731 |
| 68 | MP0009697_abnormal_copulation | 0.88512597 |
| 69 | MP0000427_abnormal_hair_cycle | 0.88350877 |
| 70 | MP0005389_reproductive_system_phenotype | 0.88212661 |
| 71 | MP0008932_abnormal_embryonic_tissue | 0.85735499 |
| 72 | MP0001929_abnormal_gametogenesis | 0.85555350 |
| 73 | MP0002210_abnormal_sex_determination | 0.85309059 |
| 74 | MP0000653_abnormal_sex_gland | 0.84080441 |
| 75 | MP0004145_abnormal_muscle_electrophysio | 0.83715177 |
| 76 | MP0002166_altered_tumor_susceptibility | 0.83297190 |
| 77 | MP0005499_abnormal_olfactory_system | 0.83147768 |
| 78 | MP0005394_taste/olfaction_phenotype | 0.83147768 |
| 79 | MP0005410_abnormal_fertilization | 0.82925536 |
| 80 | MP0002163_abnormal_gland_morphology | 0.82638420 |
| 81 | MP0002751_abnormal_autonomic_nervous | 0.82328534 |
| 82 | MP0001119_abnormal_female_reproductive | 0.79826448 |
| 83 | MP0002653_abnormal_ependyma_morphology | 0.77959479 |
| 84 | MP0005195_abnormal_posterior_eye | 0.77532719 |
| 85 | MP0001529_abnormal_vocalization | 0.77045008 |
| 86 | MP0001764_abnormal_homeostasis | 0.76398829 |
| 87 | MP0000516_abnormal_urinary_system | 0.76361279 |
| 88 | MP0005367_renal/urinary_system_phenotyp | 0.76361279 |
| 89 | MP0004142_abnormal_muscle_tone | 0.76149061 |
| 90 | MP0000631_abnormal_neuroendocrine_gland | 0.75540968 |
| 91 | MP0001145_abnormal_male_reproductive | 0.75475048 |
| 92 | MP0001663_abnormal_digestive_system | 0.74514822 |
| 93 | MP0004742_abnormal_vestibular_system | 0.74177459 |
| 94 | MP0002160_abnormal_reproductive_system | 0.74033214 |
| 95 | MP0000230_abnormal_systemic_arterial | 0.73742486 |
| 96 | MP0002277_abnormal_respiratory_mucosa | 0.73678648 |
| 97 | MP0001188_hyperpigmentation | 0.73312927 |
| 98 | MP0006276_abnormal_autonomic_nervous | 0.72455244 |
| 99 | MP0001486_abnormal_startle_reflex | 0.70956580 |
| 100 | MP0005379_endocrine/exocrine_gland_phen | 0.70731189 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.79771495 |
| 2 | Acute encephalopathy (HP:0006846) | 3.53399801 |
| 3 | Abolished electroretinogram (ERG) (HP:0000550) | 3.50379288 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.48321835 |
| 5 | Pancreatic cysts (HP:0001737) | 3.39201226 |
| 6 | Colon cancer (HP:0003003) | 3.36697176 |
| 7 | Increased CSF lactate (HP:0002490) | 3.36176709 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.28425875 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.27408929 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.20421651 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.17544838 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.16235234 |
| 13 | Hepatocellular necrosis (HP:0001404) | 2.95127349 |
| 14 | Congenital stationary night blindness (HP:0007642) | 2.91723231 |
| 15 | Abnormality of the labia minora (HP:0012880) | 2.90160484 |
| 16 | Nephronophthisis (HP:0000090) | 2.86757257 |
| 17 | Cerebral edema (HP:0002181) | 2.77149469 |
| 18 | Congenital, generalized hypertrichosis (HP:0004540) | 2.74066170 |
| 19 | True hermaphroditism (HP:0010459) | 2.73244640 |
| 20 | Abnormality of midbrain morphology (HP:0002418) | 2.63779954 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.63779954 |
| 22 | Abnormal biliary tract physiology (HP:0012439) | 2.61133003 |
| 23 | Bile duct proliferation (HP:0001408) | 2.61133003 |
| 24 | Hepatic necrosis (HP:0002605) | 2.59894038 |
| 25 | Type 2 muscle fiber atrophy (HP:0003554) | 2.59395923 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.59069210 |
| 27 | Increased serum lactate (HP:0002151) | 2.57410473 |
| 28 | Abnormality of the renal medulla (HP:0100957) | 2.50019121 |
| 29 | Septo-optic dysplasia (HP:0100842) | 2.49818026 |
| 30 | IgG deficiency (HP:0004315) | 2.47976793 |
| 31 | Pendular nystagmus (HP:0012043) | 2.46859974 |
| 32 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.46644347 |
| 33 | Methylmalonic acidemia (HP:0002912) | 2.44456970 |
| 34 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.43382914 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.42834292 |
| 36 | Optic disc pallor (HP:0000543) | 2.42207504 |
| 37 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.40080797 |
| 38 | Reticulocytopenia (HP:0001896) | 2.35823512 |
| 39 | Prostate neoplasm (HP:0100787) | 2.33404888 |
| 40 | Lactic acidosis (HP:0003128) | 2.33157361 |
| 41 | Asplenia (HP:0001746) | 2.32063415 |
| 42 | Methylmalonic aciduria (HP:0012120) | 2.30073216 |
| 43 | Meckel diverticulum (HP:0002245) | 2.29681367 |
| 44 | Renal Fanconi syndrome (HP:0001994) | 2.29263676 |
| 45 | Dyschromatopsia (HP:0007641) | 2.29204674 |
| 46 | Stomatitis (HP:0010280) | 2.28423236 |
| 47 | Abnormality of the prostate (HP:0008775) | 2.24868011 |
| 48 | Lethargy (HP:0001254) | 2.24696983 |
| 49 | Increased intramyocellular lipid droplets (HP:0012240) | 2.24144932 |
| 50 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.23919232 |
| 51 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.23747947 |
| 52 | Hyperglycinemia (HP:0002154) | 2.22669523 |
| 53 | Abnormality of the ileum (HP:0001549) | 2.20993835 |
| 54 | Exertional dyspnea (HP:0002875) | 2.20631284 |
| 55 | Neoplasm of the adrenal cortex (HP:0100641) | 2.13272866 |
| 56 | Chromsome breakage (HP:0040012) | 2.13034867 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.12924025 |
| 58 | Type I transferrin isoform profile (HP:0003642) | 2.12482434 |
| 59 | Abnormality of B cell number (HP:0010975) | 2.12410524 |
| 60 | Type II lissencephaly (HP:0007260) | 2.11983658 |
| 61 | Hyperglycinuria (HP:0003108) | 2.11277725 |
| 62 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.10251786 |
| 63 | Abnormality of glycine metabolism (HP:0010895) | 2.10251786 |
| 64 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.09892555 |
| 65 | Testicular atrophy (HP:0000029) | 2.09265085 |
| 66 | Abnormality of serum amino acid levels (HP:0003112) | 2.09024225 |
| 67 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.08481015 |
| 68 | Muscle fiber atrophy (HP:0100295) | 2.07237609 |
| 69 | Abnormality of alanine metabolism (HP:0010916) | 2.06848847 |
| 70 | Hyperalaninemia (HP:0003348) | 2.06848847 |
| 71 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.06848847 |
| 72 | Abnormal number of erythroid precursors (HP:0012131) | 2.06204986 |
| 73 | Abnormal drinking behavior (HP:0030082) | 2.05544590 |
| 74 | Polydipsia (HP:0001959) | 2.05544590 |
| 75 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.03791042 |
| 76 | Supernumerary spleens (HP:0009799) | 2.02332569 |
| 77 | Sclerocornea (HP:0000647) | 1.99593442 |
| 78 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.98761984 |
| 79 | Abnormality of chromosome stability (HP:0003220) | 1.97413219 |
| 80 | Tubular atrophy (HP:0000092) | 1.96840975 |
| 81 | Hypomagnesemia (HP:0002917) | 1.96387109 |
| 82 | Hypoproteinemia (HP:0003075) | 1.96372290 |
| 83 | Neoplasm of the adrenal gland (HP:0100631) | 1.94436907 |
| 84 | Absent thumb (HP:0009777) | 1.92777970 |
| 85 | Cystic liver disease (HP:0006706) | 1.92690283 |
| 86 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.91589932 |
| 87 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.90789838 |
| 88 | Pancytopenia (HP:0001876) | 1.89661437 |
| 89 | Increased muscle lipid content (HP:0009058) | 1.86758624 |
| 90 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.83812948 |
| 91 | Abnormal spermatogenesis (HP:0008669) | 1.83548007 |
| 92 | Attenuation of retinal blood vessels (HP:0007843) | 1.83196008 |
| 93 | Stenosis of the external auditory canal (HP:0000402) | 1.82650449 |
| 94 | Clubbing of toes (HP:0100760) | 1.82605086 |
| 95 | B lymphocytopenia (HP:0010976) | 1.82439354 |
| 96 | Hypoplasia of the pons (HP:0012110) | 1.81451556 |
| 97 | Multiple enchondromatosis (HP:0005701) | 1.79594614 |
| 98 | Respiratory difficulties (HP:0002880) | 1.79371519 |
| 99 | Panhypogammaglobulinemia (HP:0003139) | 1.78902885 |
| 100 | Posterior subcapsular cataract (HP:0007787) | 1.78678115 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 3.40488586 |
| 2 | NUAK1 | 3.39566434 |
| 3 | VRK2 | 2.94919304 |
| 4 | FRK | 2.71442836 |
| 5 | STK16 | 2.60880543 |
| 6 | EIF2AK3 | 2.50727155 |
| 7 | MAP4K2 | 2.39419913 |
| 8 | MST4 | 2.14530005 |
| 9 | TLK1 | 2.10149259 |
| 10 | MKNK2 | 2.02380582 |
| 11 | ADRBK2 | 1.99674985 |
| 12 | BUB1 | 1.99609425 |
| 13 | WNK3 | 1.99496890 |
| 14 | PLK3 | 1.99408760 |
| 15 | WNK4 | 1.98257008 |
| 16 | TAOK3 | 1.91192898 |
| 17 | TNIK | 1.88588572 |
| 18 | MKNK1 | 1.84298892 |
| 19 | EIF2AK1 | 1.80702646 |
| 20 | TSSK6 | 1.76307712 |
| 21 | CDK19 | 1.74861633 |
| 22 | BRSK2 | 1.72112847 |
| 23 | GRK1 | 1.70755707 |
| 24 | BMPR1B | 1.63134051 |
| 25 | OXSR1 | 1.62832506 |
| 26 | VRK1 | 1.61263440 |
| 27 | CDC7 | 1.59444793 |
| 28 | BCKDK | 1.54417695 |
| 29 | TAF1 | 1.51193450 |
| 30 | STK39 | 1.51111698 |
| 31 | PLK2 | 1.46026647 |
| 32 | TTK | 1.37635807 |
| 33 | TXK | 1.35499769 |
| 34 | PINK1 | 1.33783465 |
| 35 | SRPK1 | 1.31238725 |
| 36 | PBK | 1.25805364 |
| 37 | MAPKAPK3 | 1.24381614 |
| 38 | TIE1 | 1.23790943 |
| 39 | ACVR1B | 1.18413833 |
| 40 | TEC | 1.17782500 |
| 41 | EIF2AK2 | 1.14007847 |
| 42 | DYRK2 | 1.09843838 |
| 43 | PLK4 | 1.08741094 |
| 44 | BMPR2 | 1.03440625 |
| 45 | CSNK1G3 | 1.02004487 |
| 46 | TRIM28 | 1.01466750 |
| 47 | NEK1 | 1.00715638 |
| 48 | PLK1 | 0.97339732 |
| 49 | CSNK1G2 | 0.96855006 |
| 50 | MAPKAPK5 | 0.95806599 |
| 51 | CSNK1G1 | 0.89622439 |
| 52 | KIT | 0.88915815 |
| 53 | CSNK1A1L | 0.82738979 |
| 54 | PDK2 | 0.82522766 |
| 55 | DAPK1 | 0.81862659 |
| 56 | ATR | 0.81766137 |
| 57 | PHKG1 | 0.81479166 |
| 58 | PHKG2 | 0.81479166 |
| 59 | INSRR | 0.78471784 |
| 60 | MAP4K1 | 0.70375115 |
| 61 | ERBB3 | 0.64631149 |
| 62 | ALK | 0.63935265 |
| 63 | NME1 | 0.63792423 |
| 64 | EPHA4 | 0.63434736 |
| 65 | NME2 | 0.63372229 |
| 66 | PRKCQ | 0.61420367 |
| 67 | ITK | 0.61339069 |
| 68 | IKBKB | 0.61271390 |
| 69 | PIK3CA | 0.60654849 |
| 70 | STK38L | 0.59045675 |
| 71 | RPS6KA5 | 0.58124479 |
| 72 | WEE1 | 0.57246468 |
| 73 | MAP3K12 | 0.57217213 |
| 74 | CHEK2 | 0.56265439 |
| 75 | ADRBK1 | 0.53707683 |
| 76 | BRSK1 | 0.52787959 |
| 77 | FLT3 | 0.49037694 |
| 78 | TGFBR1 | 0.48941257 |
| 79 | PRKCG | 0.48234770 |
| 80 | GRK5 | 0.48025854 |
| 81 | ATM | 0.47508662 |
| 82 | SCYL2 | 0.46740374 |
| 83 | CSNK2A1 | 0.46053870 |
| 84 | AURKB | 0.45790125 |
| 85 | MAPK13 | 0.43933522 |
| 86 | PRKCI | 0.43752832 |
| 87 | CSNK2A2 | 0.41824656 |
| 88 | CSNK1A1 | 0.41642845 |
| 89 | SYK | 0.41623909 |
| 90 | WNK1 | 0.36724004 |
| 91 | PRKCA | 0.35239506 |
| 92 | DAPK2 | 0.34642730 |
| 93 | LYN | 0.33608804 |
| 94 | PRKDC | 0.30704844 |
| 95 | BTK | 0.30168133 |
| 96 | KDR | 0.27683251 |
| 97 | STK3 | 0.27316160 |
| 98 | FGFR2 | 0.26888320 |
| 99 | CSNK1E | 0.26673079 |
| 100 | DAPK3 | 0.26377756 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.88005847 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.74517609 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 2.71150282 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.68463487 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.57232298 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.55818295 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.49824957 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.20465624 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.18317870 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.14116531 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13441587 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.03741222 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 2.02109863 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.99415451 |
| 15 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.93488313 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.91716580 |
| 17 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88385704 |
| 18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.86357634 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.81484784 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.74295831 |
| 21 | RNA degradation_Homo sapiens_hsa03018 | 1.72308282 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.67485578 |
| 23 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.59655526 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.53571158 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47335978 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.44095120 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.43084257 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.42345646 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.40926320 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.38630690 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.27889938 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.26293344 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25525844 |
| 34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.24604981 |
| 35 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.24526465 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.24260618 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.24214027 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.20596159 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.19342746 |
| 40 | Base excision repair_Homo sapiens_hsa03410 | 1.18370939 |
| 41 | Huntingtons disease_Homo sapiens_hsa05016 | 1.16803575 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.08646352 |
| 43 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.07412106 |
| 44 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.05496331 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.05413521 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 1.03206809 |
| 47 | Alzheimers disease_Homo sapiens_hsa05010 | 1.01766126 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00991562 |
| 49 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.99782977 |
| 50 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.99302741 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.96533092 |
| 52 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.96474078 |
| 53 | Spliceosome_Homo sapiens_hsa03040 | 0.94021140 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.91018368 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89298629 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.88635237 |
| 57 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.84943243 |
| 58 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.83373009 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.81400016 |
| 60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.79636729 |
| 61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.78186860 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.75971495 |
| 63 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75024547 |
| 64 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.73774621 |
| 65 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.70824545 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.70688566 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69809426 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67619943 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.63516516 |
| 70 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.63457154 |
| 71 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.63074384 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.62761195 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62461576 |
| 74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.62212151 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.61649882 |
| 76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.61343284 |
| 77 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.60179731 |
| 78 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.58440857 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58019863 |
| 80 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.54326576 |
| 81 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.50670423 |
| 82 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.49985119 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48187884 |
| 84 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47950856 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.46802565 |
| 86 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.46666369 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45289739 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45121309 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44479717 |
| 90 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.43589352 |
| 91 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42896519 |
| 92 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41185731 |
| 93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.39661812 |
| 94 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37513732 |
| 95 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35084168 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.29026277 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.27640092 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.24757437 |
| 99 | Cell cycle_Homo sapiens_hsa04110 | 0.23712334 |
| 100 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.23084212 |

