

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 4.40609502 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.06192344 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.06192344 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 3.93349075 |
| 5 | response to pheromone (GO:0019236) | 3.76987187 |
| 6 | indolalkylamine metabolic process (GO:0006586) | 3.69438073 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.64009647 |
| 8 | protein complex biogenesis (GO:0070271) | 3.61679230 |
| 9 | tryptophan metabolic process (GO:0006568) | 3.60453579 |
| 10 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.59668958 |
| 11 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.59668958 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.49438906 |
| 13 | protein neddylation (GO:0045116) | 3.41925575 |
| 14 | kynurenine metabolic process (GO:0070189) | 3.38361122 |
| 15 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.37613238 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.37451741 |
| 17 | behavioral response to nicotine (GO:0035095) | 3.33165657 |
| 18 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.29228928 |
| 19 | NADH dehydrogenase complex assembly (GO:0010257) | 3.29228928 |
| 20 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.29228928 |
| 21 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.21525862 |
| 22 | viral transcription (GO:0019083) | 3.18192826 |
| 23 | L-fucose catabolic process (GO:0042355) | 3.13657472 |
| 24 | fucose catabolic process (GO:0019317) | 3.13657472 |
| 25 | L-fucose metabolic process (GO:0042354) | 3.13657472 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.12976905 |
| 27 | translational termination (GO:0006415) | 3.09885626 |
| 28 | maturation of SSU-rRNA (GO:0030490) | 3.08687160 |
| 29 | ribosomal large subunit biogenesis (GO:0042273) | 3.04889197 |
| 30 | tryptophan catabolic process (GO:0006569) | 3.04193498 |
| 31 | indole-containing compound catabolic process (GO:0042436) | 3.04193498 |
| 32 | indolalkylamine catabolic process (GO:0046218) | 3.04193498 |
| 33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.02532427 |
| 34 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.01156459 |
| 35 | electron transport chain (GO:0022900) | 3.00732156 |
| 36 | protein-cofactor linkage (GO:0018065) | 3.00547595 |
| 37 | respiratory electron transport chain (GO:0022904) | 3.00043936 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 2.99064054 |
| 39 | protein targeting to ER (GO:0045047) | 2.98876091 |
| 40 | positive regulation of defense response to virus by host (GO:0002230) | 2.98565242 |
| 41 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.97164572 |
| 42 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.93957737 |
| 43 | cytochrome complex assembly (GO:0017004) | 2.93420473 |
| 44 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.92990099 |
| 45 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.92362065 |
| 46 | negative regulation of mast cell activation (GO:0033004) | 2.90834706 |
| 47 | piRNA metabolic process (GO:0034587) | 2.89804878 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 2.88252008 |
| 49 | protein localization to endoplasmic reticulum (GO:0070972) | 2.87170123 |
| 50 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.82002670 |
| 51 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.81363378 |
| 52 | cellular response to exogenous dsRNA (GO:0071360) | 2.80841163 |
| 53 | regulation of thymocyte apoptotic process (GO:0070243) | 2.80495665 |
| 54 | translational elongation (GO:0006414) | 2.79906934 |
| 55 | positive regulation of prostaglandin secretion (GO:0032308) | 2.79556533 |
| 56 | ubiquinone biosynthetic process (GO:0006744) | 2.71224796 |
| 57 | iron-sulfur cluster assembly (GO:0016226) | 2.68080155 |
| 58 | metallo-sulfur cluster assembly (GO:0031163) | 2.68080155 |
| 59 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.68056642 |
| 60 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.67859591 |
| 61 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.65969105 |
| 62 | regulation of memory T cell differentiation (GO:0043380) | 2.65559081 |
| 63 | cellular response to interferon-beta (GO:0035458) | 2.65280196 |
| 64 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.62321807 |
| 65 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.61926385 |
| 66 | positive regulation of fatty acid transport (GO:2000193) | 2.60382877 |
| 67 | cytidine metabolic process (GO:0046087) | 2.59592414 |
| 68 | cytidine catabolic process (GO:0006216) | 2.59592414 |
| 69 | cytidine deamination (GO:0009972) | 2.59592414 |
| 70 | rRNA catabolic process (GO:0016075) | 2.57419617 |
| 71 | auditory receptor cell stereocilium organization (GO:0060088) | 2.56512250 |
| 72 | termination of RNA polymerase III transcription (GO:0006386) | 2.56239010 |
| 73 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.56239010 |
| 74 | proteasome assembly (GO:0043248) | 2.55581164 |
| 75 | chaperone-mediated protein transport (GO:0072321) | 2.55561644 |
| 76 | pseudouridine synthesis (GO:0001522) | 2.55455758 |
| 77 | indole-containing compound metabolic process (GO:0042430) | 2.55401901 |
| 78 | positive regulation of protein homodimerization activity (GO:0090073) | 2.53279823 |
| 79 | regulation of regulatory T cell differentiation (GO:0045589) | 2.50135360 |
| 80 | rRNA modification (GO:0000154) | 2.49624329 |
| 81 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.49281974 |
| 82 | response to interferon-beta (GO:0035456) | 2.47009279 |
| 83 | ubiquinone metabolic process (GO:0006743) | 2.46347352 |
| 84 | tRNA processing (GO:0008033) | 2.45953295 |
| 85 | positive regulation of T cell apoptotic process (GO:0070234) | 2.44026276 |
| 86 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.43886675 |
| 87 | translation (GO:0006412) | 2.43427661 |
| 88 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.43302769 |
| 89 | GPI anchor biosynthetic process (GO:0006506) | 2.39087154 |
| 90 | maturation of 5.8S rRNA (GO:0000460) | 2.38667517 |
| 91 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.38090631 |
| 92 | GPI anchor metabolic process (GO:0006505) | 2.37999002 |
| 93 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.37865984 |
| 94 | mannosylation (GO:0097502) | 2.36733521 |
| 95 | proton transport (GO:0015992) | 2.35576756 |
| 96 | hydrogen transport (GO:0006818) | 2.35218336 |
| 97 | regulation of cilium movement (GO:0003352) | 2.33944072 |
| 98 | primary amino compound metabolic process (GO:1901160) | 2.33006937 |
| 99 | somite development (GO:0061053) | 2.32978122 |
| 100 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.32841165 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.52963295 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.48642587 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.34952116 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.23165410 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.75851386 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.66882670 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.66211978 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.59309174 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.44969145 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.27737126 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.24417994 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22976205 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.20219683 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.18752028 |
| 15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.13891906 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.10761392 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.01562703 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.94455850 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.85788507 |
| 20 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.83061323 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.82715667 |
| 22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.81756293 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.78944418 |
| 24 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.76010801 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.75587655 |
| 26 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.72040683 |
| 27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.70942517 |
| 28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.68059696 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.63928900 |
| 30 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.59046104 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.58225373 |
| 32 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57866853 |
| 33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.56512514 |
| 34 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.55092186 |
| 35 | FUS_26573619_Chip-Seq_HEK293_Human | 1.53430301 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.53019944 |
| 37 | AR_20517297_ChIP-Seq_VCAP_Human | 1.49588257 |
| 38 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46556432 |
| 39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.46421994 |
| 40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.45173487 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.45173487 |
| 42 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.44522194 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42419422 |
| 44 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.41386971 |
| 45 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.38455463 |
| 46 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.38226506 |
| 47 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37669288 |
| 48 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.37250385 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.33983568 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.33682243 |
| 51 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.31055781 |
| 52 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.30475730 |
| 53 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.29955332 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27874484 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27874484 |
| 56 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.26900770 |
| 57 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.25328260 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.23436739 |
| 59 | NCOR_22424771_ChIP-Seq_293T_Human | 1.23341100 |
| 60 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.21892749 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.20443853 |
| 62 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17076794 |
| 63 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17076794 |
| 64 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.13452008 |
| 65 | MYB_26560356_Chip-Seq_TH2_Human | 1.13342483 |
| 66 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.11712713 |
| 67 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11179757 |
| 68 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.10846915 |
| 69 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.10284870 |
| 70 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.08701488 |
| 71 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.08185322 |
| 72 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07778182 |
| 73 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.07357244 |
| 74 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.07290221 |
| 75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.07216126 |
| 76 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07079547 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.06823374 |
| 78 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06547620 |
| 79 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.06529609 |
| 80 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03727865 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.02998389 |
| 82 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02971786 |
| 83 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.02946339 |
| 84 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.01907098 |
| 85 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.99917194 |
| 86 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.98247416 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.97289621 |
| 88 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97132582 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.96776574 |
| 90 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.95877261 |
| 91 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.95001046 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.94894738 |
| 93 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.93718154 |
| 94 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93716178 |
| 95 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.93604013 |
| 96 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.93559180 |
| 97 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.92885982 |
| 98 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.92248905 |
| 99 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90574661 |
| 100 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.90073428 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.59348620 |
| 2 | MP0005671_abnormal_response_to | 3.06770152 |
| 3 | MP0006292_abnormal_olfactory_placode | 2.75109216 |
| 4 | MP0002138_abnormal_hepatobiliary_system | 2.65665656 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.58670944 |
| 6 | MP0003195_calcinosis | 2.43277172 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.40524227 |
| 8 | MP0002102_abnormal_ear_morphology | 2.39698140 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.39247919 |
| 10 | MP0002166_altered_tumor_susceptibility | 2.29660311 |
| 11 | MP0005646_abnormal_pituitary_gland | 2.24083937 |
| 12 | MP0008872_abnormal_physiological_respon | 2.22627055 |
| 13 | MP0003646_muscle_fatigue | 2.16457905 |
| 14 | MP0002006_tumorigenesis | 2.10692482 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 2.05113444 |
| 16 | MP0000685_abnormal_immune_system | 2.04991194 |
| 17 | MP0009379_abnormal_foot_pigmentation | 1.90865065 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.88084628 |
| 19 | MP0009785_altered_susceptibility_to | 1.87828525 |
| 20 | MP0001800_abnormal_humoral_immune | 1.85761599 |
| 21 | MP0005645_abnormal_hypothalamus_physiol | 1.82229121 |
| 22 | MP0001968_abnormal_touch/_nociception | 1.80028480 |
| 23 | MP0003787_abnormal_imprinting | 1.79870825 |
| 24 | MP0005387_immune_system_phenotype | 1.73125550 |
| 25 | MP0001790_abnormal_immune_system | 1.73125550 |
| 26 | MP0002837_dystrophic_cardiac_calcinosis | 1.71032923 |
| 27 | MP0004147_increased_porphyrin_level | 1.67160718 |
| 28 | MP0002876_abnormal_thyroid_physiology | 1.66966193 |
| 29 | MP0003724_increased_susceptibility_to | 1.65803884 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.63910058 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.61050173 |
| 32 | MP0006276_abnormal_autonomic_nervous | 1.60969113 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.50316632 |
| 34 | MP0009764_decreased_sensitivity_to | 1.50131092 |
| 35 | MP0004142_abnormal_muscle_tone | 1.48135861 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.47665176 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.45884819 |
| 38 | MP0002723_abnormal_immune_serum | 1.42673951 |
| 39 | MP0005171_absent_coat_pigmentation | 1.36129910 |
| 40 | MP0002452_abnormal_antigen_presenting | 1.33220270 |
| 41 | MP0004885_abnormal_endolymph | 1.30192947 |
| 42 | MP0009333_abnormal_splenocyte_physiolog | 1.30049786 |
| 43 | MP0005084_abnormal_gallbladder_morpholo | 1.25277576 |
| 44 | MP0005389_reproductive_system_phenotype | 1.24111478 |
| 45 | MP0004742_abnormal_vestibular_system | 1.23313687 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.21793713 |
| 47 | MP0004145_abnormal_muscle_electrophysio | 1.21154365 |
| 48 | MP0009278_abnormal_bone_marrow | 1.20670619 |
| 49 | MP0005167_abnormal_blood-brain_barrier | 1.19595838 |
| 50 | MP0008775_abnormal_heart_ventricle | 1.18965797 |
| 51 | MP0001905_abnormal_dopamine_level | 1.18159003 |
| 52 | MP0006082_CNS_inflammation | 1.16155978 |
| 53 | MP0002420_abnormal_adaptive_immunity | 1.15922717 |
| 54 | MP0001819_abnormal_immune_cell | 1.15767215 |
| 55 | MP0001984_abnormal_olfaction | 1.15490462 |
| 56 | MP0000569_abnormal_digit_pigmentation | 1.12980021 |
| 57 | MP0002736_abnormal_nociception_after | 1.12506702 |
| 58 | MP0002653_abnormal_ependyma_morphology | 1.10576141 |
| 59 | MP0008995_early_reproductive_senescence | 1.10027176 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.09386255 |
| 61 | MP0003878_abnormal_ear_physiology | 1.09386255 |
| 62 | MP0002160_abnormal_reproductive_system | 1.05050338 |
| 63 | MP0010155_abnormal_intestine_physiology | 1.03979619 |
| 64 | MP0003186_abnormal_redox_activity | 1.03580580 |
| 65 | MP0001501_abnormal_sleep_pattern | 1.03349174 |
| 66 | MP0002095_abnormal_skin_pigmentation | 1.01991108 |
| 67 | MP0003763_abnormal_thymus_physiology | 1.01223923 |
| 68 | MP0006036_abnormal_mitochondrial_physio | 1.00972484 |
| 69 | MP0000230_abnormal_systemic_arterial | 1.00779131 |
| 70 | MP0001919_abnormal_reproductive_system | 1.00461468 |
| 71 | MP0005025_abnormal_response_to | 1.00378745 |
| 72 | MP0002638_abnormal_pupillary_reflex | 0.98584391 |
| 73 | MP0003786_premature_aging | 0.97483393 |
| 74 | MP0001485_abnormal_pinna_reflex | 0.97002059 |
| 75 | MP0002163_abnormal_gland_morphology | 0.96476314 |
| 76 | MP0003252_abnormal_bile_duct | 0.94217206 |
| 77 | MP0003880_abnormal_central_pattern | 0.94032781 |
| 78 | MP0003866_abnormal_defecation | 0.93385482 |
| 79 | MP0009745_abnormal_behavioral_response | 0.93077877 |
| 80 | MP0002272_abnormal_nervous_system | 0.91151762 |
| 81 | MP0008058_abnormal_DNA_repair | 0.90425923 |
| 82 | MP0000427_abnormal_hair_cycle | 0.89889970 |
| 83 | MP0005253_abnormal_eye_physiology | 0.86307574 |
| 84 | MP0000716_abnormal_immune_system | 0.84753177 |
| 85 | MP0002933_joint_inflammation | 0.83805825 |
| 86 | MP0005499_abnormal_olfactory_system | 0.82868971 |
| 87 | MP0005394_taste/olfaction_phenotype | 0.82868971 |
| 88 | MP0001970_abnormal_pain_threshold | 0.80401919 |
| 89 | MP0002733_abnormal_thermal_nociception | 0.80302917 |
| 90 | MP0005410_abnormal_fertilization | 0.80178860 |
| 91 | MP0002234_abnormal_pharynx_morphology | 0.80084261 |
| 92 | MP0009697_abnormal_copulation | 0.76606922 |
| 93 | MP0002398_abnormal_bone_marrow | 0.76388223 |
| 94 | MP0002277_abnormal_respiratory_mucosa | 0.76172973 |
| 95 | MP0001845_abnormal_inflammatory_respons | 0.74712243 |
| 96 | MP0001529_abnormal_vocalization | 0.74230723 |
| 97 | MP0005636_abnormal_mineral_homeostasis | 0.73364953 |
| 98 | MP0003121_genomic_imprinting | 0.71354477 |
| 99 | MP0000689_abnormal_spleen_morphology | 0.70125381 |
| 100 | MP0003436_decreased_susceptibility_to | 0.69718434 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.19538996 |
| 2 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.92823642 |
| 3 | Abnormality of B cell number (HP:0010975) | 3.72429974 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.72045953 |
| 5 | B lymphocytopenia (HP:0010976) | 3.71745062 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.64425823 |
| 7 | Abolished electroretinogram (ERG) (HP:0000550) | 3.52827517 |
| 8 | Increased CSF lactate (HP:0002490) | 3.45802867 |
| 9 | Panhypogammaglobulinemia (HP:0003139) | 3.45475358 |
| 10 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.42517149 |
| 11 | Pancreatic cysts (HP:0001737) | 3.42417353 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.39155484 |
| 13 | IgG deficiency (HP:0004315) | 3.36491641 |
| 14 | Stomatitis (HP:0010280) | 3.35977989 |
| 15 | Congenital stationary night blindness (HP:0007642) | 3.30798690 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 3.29642697 |
| 17 | Molar tooth sign on MRI (HP:0002419) | 3.29642697 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.25705865 |
| 19 | Acute encephalopathy (HP:0006846) | 3.23330507 |
| 20 | Hypoproteinemia (HP:0003075) | 3.17756992 |
| 21 | Increased hepatocellular lipid droplets (HP:0006565) | 3.16713147 |
| 22 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.15121593 |
| 23 | Hepatocellular necrosis (HP:0001404) | 3.12290256 |
| 24 | Decreased central vision (HP:0007663) | 3.06761577 |
| 25 | Severe combined immunodeficiency (HP:0004430) | 3.06362903 |
| 26 | Pancreatic fibrosis (HP:0100732) | 3.04504143 |
| 27 | Congenital, generalized hypertrichosis (HP:0004540) | 3.03679219 |
| 28 | Nephronophthisis (HP:0000090) | 3.02279431 |
| 29 | Lipid accumulation in hepatocytes (HP:0006561) | 3.01434783 |
| 30 | Thyroiditis (HP:0100646) | 2.96076872 |
| 31 | Hepatic necrosis (HP:0002605) | 2.78053300 |
| 32 | Hypothermia (HP:0002045) | 2.74608271 |
| 33 | Abnormality of the prostate (HP:0008775) | 2.73868246 |
| 34 | Pendular nystagmus (HP:0012043) | 2.72070552 |
| 35 | True hermaphroditism (HP:0010459) | 2.70753770 |
| 36 | Type II lissencephaly (HP:0007260) | 2.68855180 |
| 37 | Abnormality of the renal medulla (HP:0100957) | 2.64492726 |
| 38 | Attenuation of retinal blood vessels (HP:0007843) | 2.52176180 |
| 39 | Stenosis of the external auditory canal (HP:0000402) | 2.45447197 |
| 40 | Type 2 muscle fiber atrophy (HP:0003554) | 2.44976946 |
| 41 | Abnormality of the renal cortex (HP:0011035) | 2.44245020 |
| 42 | Cerebral edema (HP:0002181) | 2.41993834 |
| 43 | Renal Fanconi syndrome (HP:0001994) | 2.38191009 |
| 44 | Increased serum lactate (HP:0002151) | 2.37911474 |
| 45 | Optic disc pallor (HP:0000543) | 2.33221827 |
| 46 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.28581890 |
| 47 | Absent/shortened dynein arms (HP:0200106) | 2.28581890 |
| 48 | T lymphocytopenia (HP:0005403) | 2.28457274 |
| 49 | Increased intramyocellular lipid droplets (HP:0012240) | 2.28136417 |
| 50 | Combined immunodeficiency (HP:0005387) | 2.26239797 |
| 51 | Abnormality of T cell number (HP:0011839) | 2.25711992 |
| 52 | Reticulocytopenia (HP:0001896) | 2.24014107 |
| 53 | Medial flaring of the eyebrow (HP:0010747) | 2.23873174 |
| 54 | Abnormality of alanine metabolism (HP:0010916) | 2.22645427 |
| 55 | Hyperalaninemia (HP:0003348) | 2.22645427 |
| 56 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.22645427 |
| 57 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.20403634 |
| 58 | Increased corneal curvature (HP:0100692) | 2.20104974 |
| 59 | Keratoconus (HP:0000563) | 2.20104974 |
| 60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.19828469 |
| 61 | Exertional dyspnea (HP:0002875) | 2.19418367 |
| 62 | Abnormality of T cells (HP:0002843) | 2.18927253 |
| 63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.18836831 |
| 64 | Polydipsia (HP:0001959) | 2.14355907 |
| 65 | Abnormal drinking behavior (HP:0030082) | 2.14355907 |
| 66 | Methylmalonic acidemia (HP:0002912) | 2.10809748 |
| 67 | Lactic acidosis (HP:0003128) | 2.04921028 |
| 68 | Tubular atrophy (HP:0000092) | 2.01167922 |
| 69 | Colon cancer (HP:0003003) | 1.95215546 |
| 70 | Renal cortical cysts (HP:0000803) | 1.95039439 |
| 71 | Chronic diarrhea (HP:0002028) | 1.94673297 |
| 72 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.93181562 |
| 73 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.93181562 |
| 74 | Polyuria (HP:0000103) | 1.92790394 |
| 75 | Cystic liver disease (HP:0006706) | 1.90652224 |
| 76 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.89425309 |
| 77 | Absent thumb (HP:0009777) | 1.88904775 |
| 78 | Increased muscle lipid content (HP:0009058) | 1.88075355 |
| 79 | Muscle fiber atrophy (HP:0100295) | 1.86352522 |
| 80 | Methylmalonic aciduria (HP:0012120) | 1.86020711 |
| 81 | Aplastic anemia (HP:0001915) | 1.85801035 |
| 82 | Abnormality of eosinophils (HP:0001879) | 1.84634491 |
| 83 | Sclerocornea (HP:0000647) | 1.84494415 |
| 84 | Abnormal number of erythroid precursors (HP:0012131) | 1.82280414 |
| 85 | Abnormality of T cell physiology (HP:0011840) | 1.81959346 |
| 86 | Lethargy (HP:0001254) | 1.81290505 |
| 87 | Constricted visual fields (HP:0001133) | 1.80142076 |
| 88 | Abnormal biliary tract physiology (HP:0012439) | 1.78764324 |
| 89 | Bile duct proliferation (HP:0001408) | 1.78764324 |
| 90 | Decreased circulating renin level (HP:0003351) | 1.78273867 |
| 91 | Respiratory failure (HP:0002878) | 1.77195178 |
| 92 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.76835391 |
| 93 | Eosinophilia (HP:0001880) | 1.75665139 |
| 94 | Hypoplasia of the thymus (HP:0000778) | 1.73395583 |
| 95 | Congenital hepatic fibrosis (HP:0002612) | 1.72477530 |
| 96 | Chronic hepatic failure (HP:0100626) | 1.70619244 |
| 97 | Abnormality of renal resorption (HP:0011038) | 1.69133324 |
| 98 | Myositis (HP:0100614) | 1.67925787 |
| 99 | Asplenia (HP:0001746) | 1.67691366 |
| 100 | Abnormal ciliary motility (HP:0012262) | 1.67505187 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 3.53162133 |
| 2 | TXK | 3.39281123 |
| 3 | TAOK3 | 3.21757265 |
| 4 | TIE1 | 3.00050025 |
| 5 | ZAK | 2.95330592 |
| 6 | EIF2AK3 | 2.89985795 |
| 7 | ADRBK2 | 2.71129496 |
| 8 | NUAK1 | 2.70296832 |
| 9 | GRK1 | 2.61529331 |
| 10 | TLK1 | 2.54543871 |
| 11 | TEC | 2.36721739 |
| 12 | MAP4K2 | 2.33818237 |
| 13 | WNK4 | 1.95163017 |
| 14 | EIF2AK1 | 1.78052185 |
| 15 | ITK | 1.77107507 |
| 16 | BCKDK | 1.74127813 |
| 17 | VRK2 | 1.61679210 |
| 18 | CDK19 | 1.56332844 |
| 19 | KIT | 1.54326763 |
| 20 | FES | 1.51559643 |
| 21 | BMPR1B | 1.46738545 |
| 22 | PINK1 | 1.37239716 |
| 23 | KDR | 1.36018317 |
| 24 | BTK | 1.35737931 |
| 25 | MAP3K12 | 1.33662196 |
| 26 | MAP4K1 | 1.30134153 |
| 27 | STK39 | 1.24649690 |
| 28 | OXSR1 | 1.21386477 |
| 29 | BMPR2 | 1.20303603 |
| 30 | MAPK13 | 1.18331718 |
| 31 | IKBKB | 1.15439975 |
| 32 | STK16 | 1.13633335 |
| 33 | MAPKAPK3 | 1.13003668 |
| 34 | SYK | 1.11677556 |
| 35 | WNK3 | 1.10118498 |
| 36 | MUSK | 1.03519964 |
| 37 | VRK1 | 0.95617620 |
| 38 | MKNK2 | 0.95187638 |
| 39 | CSNK1G3 | 0.90531233 |
| 40 | RPS6KA5 | 0.88464637 |
| 41 | EIF2AK2 | 0.84797442 |
| 42 | INSRR | 0.83688633 |
| 43 | PLK4 | 0.83661588 |
| 44 | PRKCQ | 0.82793079 |
| 45 | LCK | 0.81409890 |
| 46 | LYN | 0.79912786 |
| 47 | PHKG2 | 0.78918810 |
| 48 | PHKG1 | 0.78918810 |
| 49 | CSNK1G2 | 0.78004744 |
| 50 | MKNK1 | 0.76383944 |
| 51 | MST4 | 0.75999965 |
| 52 | BCR | 0.72265644 |
| 53 | CSNK1G1 | 0.71948713 |
| 54 | PLK3 | 0.68834004 |
| 55 | PASK | 0.68593681 |
| 56 | ADRBK1 | 0.67284442 |
| 57 | CSF1R | 0.66908427 |
| 58 | MAPKAPK5 | 0.62827561 |
| 59 | MAP2K6 | 0.62645235 |
| 60 | CSNK1A1L | 0.62093057 |
| 61 | FLT3 | 0.61225919 |
| 62 | GRK6 | 0.60557853 |
| 63 | MAP2K2 | 0.59504296 |
| 64 | IGF1R | 0.57698662 |
| 65 | PLK2 | 0.57632263 |
| 66 | DYRK2 | 0.57238712 |
| 67 | GRK7 | 0.55757517 |
| 68 | CAMK1D | 0.55638520 |
| 69 | OBSCN | 0.54371214 |
| 70 | IKBKE | 0.54133235 |
| 71 | NEK1 | 0.53980379 |
| 72 | ERBB3 | 0.53800751 |
| 73 | PIK3CA | 0.53444744 |
| 74 | DAPK2 | 0.52415033 |
| 75 | MAP3K4 | 0.52352020 |
| 76 | PRKCE | 0.52338469 |
| 77 | CDK8 | 0.51867736 |
| 78 | CHUK | 0.50117015 |
| 79 | LIMK1 | 0.49990747 |
| 80 | CAMKK2 | 0.49185426 |
| 81 | MYLK | 0.48347490 |
| 82 | ATR | 0.48135709 |
| 83 | ABL1 | 0.46443718 |
| 84 | TGFBR1 | 0.45855747 |
| 85 | CAMK1 | 0.45060188 |
| 86 | TSSK6 | 0.43481436 |
| 87 | NME1 | 0.43251267 |
| 88 | PDK2 | 0.42136053 |
| 89 | PRKACA | 0.41635039 |
| 90 | TRPM7 | 0.41169428 |
| 91 | PRKCA | 0.40732217 |
| 92 | PRKCG | 0.40592182 |
| 93 | JAK3 | 0.37346624 |
| 94 | CSNK2A1 | 0.36599011 |
| 95 | CSNK2A2 | 0.35925364 |
| 96 | PIK3CG | 0.35836424 |
| 97 | SRPK1 | 0.35260243 |
| 98 | DAPK1 | 0.34209568 |
| 99 | GRK5 | 0.34184798 |
| 100 | TRIM28 | 0.33735375 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.78764047 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.09123537 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.08953038 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.01963060 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.01073911 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.96827843 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.84160426 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.59218549 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.58094197 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.54616317 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.50199716 |
| 12 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.41577486 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.37083825 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.85526409 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.83424580 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.81551655 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.71635666 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.70650149 |
| 19 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.69270069 |
| 20 | RNA polymerase_Homo sapiens_hsa03020 | 1.63978681 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.58749597 |
| 22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.58434401 |
| 23 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58433388 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.57803706 |
| 25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.55816325 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.51499743 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.49772395 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.47074440 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.45853891 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37098428 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.35115885 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.33005618 |
| 33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21745247 |
| 34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.21211067 |
| 35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.13405429 |
| 36 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.09330055 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.08927219 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.08224302 |
| 39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06931532 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03619066 |
| 41 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.02495419 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.00602595 |
| 43 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.99641647 |
| 44 | Viral myocarditis_Homo sapiens_hsa05416 | 0.97932898 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.97539044 |
| 46 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89579120 |
| 47 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86434384 |
| 48 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.84651186 |
| 49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.84258934 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.84114583 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82003424 |
| 52 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80247177 |
| 53 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78712597 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.77824030 |
| 55 | Mismatch repair_Homo sapiens_hsa03430 | 0.76139001 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.75937783 |
| 57 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.73306547 |
| 58 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.71636943 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.71172070 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.68628182 |
| 61 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67787036 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65544424 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65344803 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63105580 |
| 65 | RNA transport_Homo sapiens_hsa03013 | 0.62527444 |
| 66 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.62314559 |
| 67 | Spliceosome_Homo sapiens_hsa03040 | 0.59049591 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57945858 |
| 69 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57174750 |
| 70 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.57100439 |
| 71 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54475901 |
| 72 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.53751914 |
| 73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.52956486 |
| 74 | Base excision repair_Homo sapiens_hsa03410 | 0.51329013 |
| 75 | Leishmaniasis_Homo sapiens_hsa05140 | 0.50301926 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49911545 |
| 77 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48466721 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47270569 |
| 79 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46107916 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44639121 |
| 81 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.42729248 |
| 82 | Morphine addiction_Homo sapiens_hsa05032 | 0.42519957 |
| 83 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42233102 |
| 84 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.39135977 |
| 85 | Taste transduction_Homo sapiens_hsa04742 | 0.38993526 |
| 86 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.32219965 |
| 87 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.31633887 |
| 88 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30566330 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.30537507 |
| 90 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30297004 |
| 91 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30133473 |
| 92 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.29311708 |
| 93 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.29137072 |
| 94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.25932884 |
| 95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.25497588 |
| 96 | Nicotine addiction_Homo sapiens_hsa05033 | 0.25366224 |
| 97 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.24849279 |
| 98 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.22595849 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21505026 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.20607175 |

