RPL7P27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)5.94910645
2ATP synthesis coupled proton transport (GO:0015986)5.85712001
3energy coupled proton transport, down electrochemical gradient (GO:0015985)5.85712001
4ribosomal small subunit assembly (GO:0000028)5.73395975
5translational termination (GO:0006415)5.68330282
6maturation of SSU-rRNA (GO:0030490)5.55471730
7mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.36962914
8behavioral response to nicotine (GO:0035095)5.29857140
9ribosomal small subunit biogenesis (GO:0042274)5.00311864
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.99706648
11protein targeting to ER (GO:0045047)4.91568800
12cotranslational protein targeting to membrane (GO:0006613)4.90890478
13translational elongation (GO:0006414)4.78191469
14establishment of protein localization to endoplasmic reticulum (GO:0072599)4.69770940
15protein localization to endoplasmic reticulum (GO:0070972)4.67815540
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.65702007
17DNA deamination (GO:0045006)4.56583459
18establishment of protein localization to mitochondrial membrane (GO:0090151)4.54668874
19protein neddylation (GO:0045116)4.47720092
20viral life cycle (GO:0019058)4.31810236
21mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.23626696
22tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.22953790
23RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.22953790
24cellular protein complex disassembly (GO:0043624)4.17606257
25ribosomal large subunit biogenesis (GO:0042273)4.04689432
26nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.04420411
27water-soluble vitamin biosynthetic process (GO:0042364)3.95002174
28translational initiation (GO:0006413)3.83985098
29protein complex biogenesis (GO:0070271)3.81855362
30electron transport chain (GO:0022900)3.76982318
31respiratory electron transport chain (GO:0022904)3.75937446
32mitochondrial respiratory chain complex I assembly (GO:0032981)3.72907096
33NADH dehydrogenase complex assembly (GO:0010257)3.72907096
34mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.72907096
35regulation of cilium movement (GO:0003352)3.68056274
36chaperone-mediated protein transport (GO:0072321)3.53047378
37protein complex disassembly (GO:0043241)3.50318098
38kynurenine metabolic process (GO:0070189)3.50316296
39kidney morphogenesis (GO:0060993)3.46893103
40mitochondrial respiratory chain complex assembly (GO:0033108)3.41567265
41macromolecular complex disassembly (GO:0032984)3.36976010
42translation (GO:0006412)3.33131482
43nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.29796175
44regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.29567622
45ATP biosynthetic process (GO:0006754)3.26458018
46purine nucleoside triphosphate biosynthetic process (GO:0009145)3.26398764
47purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.23692373
48protein targeting to membrane (GO:0006612)3.19070707
49detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.17172634
50GTP biosynthetic process (GO:0006183)3.14934498
51epithelial cilium movement (GO:0003351)3.14460244
52exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.14151520
53pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.13781041
54protein polyglutamylation (GO:0018095)3.12730903
55cellular component biogenesis (GO:0044085)3.10197539
56hydrogen ion transmembrane transport (GO:1902600)3.09840520
57nuclear-transcribed mRNA catabolic process (GO:0000956)3.04741248
58indole-containing compound catabolic process (GO:0042436)3.02506920
59indolalkylamine catabolic process (GO:0046218)3.02506920
60tryptophan catabolic process (GO:0006569)3.02506920
61preassembly of GPI anchor in ER membrane (GO:0016254)2.99051932
62aldehyde catabolic process (GO:0046185)2.96991796
63nonmotile primary cilium assembly (GO:0035058)2.96202895
64ribonucleoprotein complex biogenesis (GO:0022613)2.92847618
65regulation of microtubule-based movement (GO:0060632)2.89938988
66mRNA catabolic process (GO:0006402)2.89522876
67somite development (GO:0061053)2.89324203
68proton transport (GO:0015992)2.86751859
69indolalkylamine metabolic process (GO:0006586)2.82192817
70ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81205815
71hydrogen transport (GO:0006818)2.80566942
72rRNA modification (GO:0000154)2.76826955
73amine catabolic process (GO:0009310)2.75504621
74cellular biogenic amine catabolic process (GO:0042402)2.75504621
75negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.71759218
76axoneme assembly (GO:0035082)2.70571028
77fucose catabolic process (GO:0019317)2.68446840
78L-fucose metabolic process (GO:0042354)2.68446840
79L-fucose catabolic process (GO:0042355)2.68446840
80pyrimidine nucleotide catabolic process (GO:0006244)2.67667172
81negative regulation of heart rate (GO:0010459)2.66953913
82axonemal dynein complex assembly (GO:0070286)2.66803129
83mannosylation (GO:0097502)2.66718296
84positive regulation of defense response to virus by host (GO:0002230)2.66652968
85piRNA metabolic process (GO:0034587)2.66431499
86cytochrome complex assembly (GO:0017004)2.66210978
87parturition (GO:0007567)2.63252963
88rRNA metabolic process (GO:0016072)2.62463194
89synaptic transmission, cholinergic (GO:0007271)2.62330628
90rRNA processing (GO:0006364)2.61880404
91cell proliferation in forebrain (GO:0021846)2.61666448
92UTP biosynthetic process (GO:0006228)2.60405504
93negative regulation of telomere maintenance (GO:0032205)2.60090013
94respiratory chain complex IV assembly (GO:0008535)2.58950800
95tryptophan metabolic process (GO:0006568)2.57751203
96pseudouridine synthesis (GO:0001522)2.57554678
97cellular response to interferon-beta (GO:0035458)2.57017887
98RNA catabolic process (GO:0006401)2.55147697
99positive regulation of fatty acid transport (GO:2000193)2.53228061
100UTP metabolic process (GO:0046051)2.52624651

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.12825853
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.75501827
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.72502079
4VDR_22108803_ChIP-Seq_LS180_Human3.13815273
5ZNF274_21170338_ChIP-Seq_K562_Hela2.93248519
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.88626986
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.88565356
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.73058013
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.62593870
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.22350482
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.14853040
12IRF1_19129219_ChIP-ChIP_H3396_Human2.00564644
13EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.88967971
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.84002274
15VDR_23849224_ChIP-Seq_CD4+_Human1.82203339
16FLI1_27457419_Chip-Seq_LIVER_Mouse1.79810992
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.71789290
18ETV2_25802403_ChIP-Seq_MESCs_Mouse1.71221865
19ELF1_17652178_ChIP-ChIP_JURKAT_Human1.68610081
20TP53_22573176_ChIP-Seq_HFKS_Human1.60718984
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.60429349
22PCGF2_27294783_Chip-Seq_NPCs_Mouse1.59503494
23MYC_18940864_ChIP-ChIP_HL60_Human1.55131897
24HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.53196196
25EWS_26573619_Chip-Seq_HEK293_Human1.51277835
26GATA3_21878914_ChIP-Seq_MCF-7_Human1.50272804
27RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46458938
28BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45843180
29MYC_18555785_ChIP-Seq_MESCs_Mouse1.45409475
30GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.45405452
31ELK1_19687146_ChIP-ChIP_HELA_Human1.45041770
32FOXP3_21729870_ChIP-Seq_TREG_Human1.40723231
33FOXA1_25329375_ChIP-Seq_VCAP_Human1.35439352
34FOXA1_27270436_Chip-Seq_PROSTATE_Human1.35439352
35TAF2_19829295_ChIP-Seq_ESCs_Human1.34647058
36CTBP1_25329375_ChIP-Seq_LNCAP_Human1.34581152
37SRF_21415370_ChIP-Seq_HL-1_Mouse1.32063022
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.31126936
39NANOG_20526341_ChIP-Seq_ESCs_Human1.30609458
40GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.29052196
41TDRD3_21172665_ChIP-Seq_MCF-7_Human1.27205659
42FUS_26573619_Chip-Seq_HEK293_Human1.26687543
43NCOR_22424771_ChIP-Seq_293T_Human1.25378069
44GBX2_23144817_ChIP-Seq_PC3_Human1.24931218
45ER_23166858_ChIP-Seq_MCF-7_Human1.23057363
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.22954644
47ERA_21632823_ChIP-Seq_H3396_Human1.22384207
48MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.22124585
49EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.21671049
50HOXB7_26014856_ChIP-Seq_BT474_Human1.20790990
51AR_20517297_ChIP-Seq_VCAP_Human1.20746550
52REST_21632747_ChIP-Seq_MESCs_Mouse1.20743895
53TTF2_22483619_ChIP-Seq_HELA_Human1.20398079
54CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18462997
55P300_19829295_ChIP-Seq_ESCs_Human1.17946511
56IGF1R_20145208_ChIP-Seq_DFB_Human1.15849319
57SOX2_19829295_ChIP-Seq_ESCs_Human1.15825957
58NANOG_19829295_ChIP-Seq_ESCs_Human1.15825957
59CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.15803706
60EZH2_27304074_Chip-Seq_ESCs_Mouse1.13761507
61FOXH1_21741376_ChIP-Seq_EPCs_Human1.13391557
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.13287221
63EZH2_27294783_Chip-Seq_ESCs_Mouse1.13008458
64CBP_20019798_ChIP-Seq_JUKART_Human1.11008978
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.11008978
66AUTS2_25519132_ChIP-Seq_293T-REX_Human1.10888725
67TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10294763
68JARID2_20064375_ChIP-Seq_MESCs_Mouse1.09717112
69E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.08934037
70FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.08874213
71ZFP57_27257070_Chip-Seq_ESCs_Mouse1.07925124
72CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.07331746
73P53_21459846_ChIP-Seq_SAOS-2_Human1.06207413
74IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.06200485
75SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.04328527
76RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.04083042
77MYC_19829295_ChIP-Seq_ESCs_Human1.03905206
78NFE2_27457419_Chip-Seq_LIVER_Mouse1.03537441
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.03091567
80PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.01481044
81KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01236666
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.00940492
83CTBP2_25329375_ChIP-Seq_LNCAP_Human0.99302807
84PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.96358490
85FOXH1_21741376_ChIP-Seq_ESCs_Human0.94567697
86GABP_19822575_ChIP-Seq_HepG2_Human0.94044072
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.93254373
88TAF15_26573619_Chip-Seq_HEK293_Human0.92779183
89SUZ12_27294783_Chip-Seq_ESCs_Mouse0.92740658
90RNF2_27304074_Chip-Seq_NSC_Mouse0.92231573
91OCT4_20526341_ChIP-Seq_ESCs_Human0.92207772
92GATA3_26560356_Chip-Seq_TH2_Human0.90960657
93ERG_20517297_ChIP-Seq_VCAP_Human0.90344542
94MYC_18358816_ChIP-ChIP_MESCs_Mouse0.90029051
95TCF4_22108803_ChIP-Seq_LS180_Human0.89775964
96POU5F1_16153702_ChIP-ChIP_HESCs_Human0.89773875
97E2F1_20622854_ChIP-Seq_HELA_Human0.89692829
98YY1_21170310_ChIP-Seq_MESCs_Mouse0.89645794
99STAT1_20625510_ChIP-Seq_HELA_Human0.89268783
100EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.87959429

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.63739388
2MP0006292_abnormal_olfactory_placode4.59729459
3MP0003787_abnormal_imprinting3.11741883
4MP0003646_muscle_fatigue2.91343462
5MP0008877_abnormal_DNA_methylation2.73057832
6MP0001968_abnormal_touch/_nociception2.39898862
7MP0005646_abnormal_pituitary_gland2.34132989
8MP0002102_abnormal_ear_morphology2.33959150
9MP0004142_abnormal_muscle_tone2.30940885
10MP0002138_abnormal_hepatobiliary_system2.26210795
11MP0002837_dystrophic_cardiac_calcinosis2.19152064
12MP0008789_abnormal_olfactory_epithelium2.12369160
13MP0003806_abnormal_nucleotide_metabolis2.07490037
14MP0002876_abnormal_thyroid_physiology2.00169208
15MP0008875_abnormal_xenobiotic_pharmacok1.97417284
16MP0004885_abnormal_endolymph1.93670400
17MP0005084_abnormal_gallbladder_morpholo1.91848395
18MP0001986_abnormal_taste_sensitivity1.91549102
19MP0005671_abnormal_response_to1.84633958
20MP0008872_abnormal_physiological_respon1.78045097
21MP0002163_abnormal_gland_morphology1.77261176
22MP0002736_abnormal_nociception_after1.74917862
23MP0001835_abnormal_antigen_presentation1.74537613
24MP0003122_maternal_imprinting1.73595407
25MP0002653_abnormal_ependyma_morphology1.71271515
26MP0005551_abnormal_eye_electrophysiolog1.67201887
27MP0006072_abnormal_retinal_apoptosis1.63878951
28MP0001984_abnormal_olfaction1.63046783
29MP0001485_abnormal_pinna_reflex1.60705837
30MP0003121_genomic_imprinting1.58573837
31MP0005394_taste/olfaction_phenotype1.56814058
32MP0005499_abnormal_olfactory_system1.56814058
33MP0001293_anophthalmia1.55780820
34MP0000372_irregular_coat_pigmentation1.55678819
35MP0004145_abnormal_muscle_electrophysio1.54845515
36MP0005377_hearing/vestibular/ear_phenot1.50177059
37MP0003878_abnormal_ear_physiology1.50177059
38MP0002272_abnormal_nervous_system1.42722958
39MP0006276_abnormal_autonomic_nervous1.37565218
40MP0002733_abnormal_thermal_nociception1.35934952
41MP0005645_abnormal_hypothalamus_physiol1.33044304
42MP0001970_abnormal_pain_threshold1.30961947
43MP0002938_white_spotting1.30390225
44MP0005389_reproductive_system_phenotype1.28634136
45MP0001440_abnormal_grooming_behavior1.28571306
46MP0001905_abnormal_dopamine_level1.25130086
47MP0000631_abnormal_neuroendocrine_gland1.24718083
48MP0004147_increased_porphyrin_level1.23764498
49MP0003136_yellow_coat_color1.23494725
50MP0008775_abnormal_heart_ventricle1.23065483
51MP0004742_abnormal_vestibular_system1.20009855
52MP0001919_abnormal_reproductive_system1.18368769
53MP0009745_abnormal_behavioral_response1.17927731
54MP0001529_abnormal_vocalization1.13765253
55MP0003879_abnormal_hair_cell1.10824055
56MP0002160_abnormal_reproductive_system1.10037183
57MP0001486_abnormal_startle_reflex1.07280975
58MP0002572_abnormal_emotion/affect_behav1.03125211
59MP0005195_abnormal_posterior_eye1.02822062
60MP0002234_abnormal_pharynx_morphology1.02295469
61MP0003186_abnormal_redox_activity0.99976001
62MP0000427_abnormal_hair_cycle0.97268537
63MP0001963_abnormal_hearing_physiology0.96073052
64MP0000685_abnormal_immune_system0.95215020
65MP0003880_abnormal_central_pattern0.94508371
66MP0002557_abnormal_social/conspecific_i0.92906161
67MP0003011_delayed_dark_adaptation0.92302526
68MP0000026_abnormal_inner_ear0.90887851
69MP0002638_abnormal_pupillary_reflex0.90781595
70MP0008058_abnormal_DNA_repair0.90630104
71MP0001502_abnormal_circadian_rhythm0.90520403
72MP0002148_abnormal_hypersensitivity_rea0.89638101
73MP0005253_abnormal_eye_physiology0.89454702
74MP0003866_abnormal_defecation0.86279312
75MP0002752_abnormal_somatic_nervous0.85515375
76MP0000778_abnormal_nervous_system0.85092183
77MP0002063_abnormal_learning/memory/cond0.84472735
78MP0002734_abnormal_mechanical_nocicepti0.82513150
79MP0000049_abnormal_middle_ear0.81668179
80MP0001800_abnormal_humoral_immune0.81372728
81MP0003195_calcinosis0.81309913
82MP0000230_abnormal_systemic_arterial0.81082488
83MP0002095_abnormal_skin_pigmentation0.80409141
84MP0005379_endocrine/exocrine_gland_phen0.78721679
85MP0009764_decreased_sensitivity_to0.76979701
86MP0002184_abnormal_innervation0.74911799
87MP0002067_abnormal_sensory_capabilities0.74689725
88MP0004133_heterotaxia0.73912472
89MP0002735_abnormal_chemical_nociception0.73485556
90MP0005636_abnormal_mineral_homeostasis0.72748546
91MP0008995_early_reproductive_senescence0.71921321
92MP0000955_abnormal_spinal_cord0.71240763
93MP0005167_abnormal_blood-brain_barrier0.70277814
94MP0001663_abnormal_digestive_system0.69838314
95MP0003718_maternal_effect0.69779925
96MP0009046_muscle_twitch0.67923536
97MP0002210_abnormal_sex_determination0.66573107
98MP0009333_abnormal_splenocyte_physiolog0.66276146
99MP0002928_abnormal_bile_duct0.64422148
100MP0003938_abnormal_ear_development0.64016677

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.38230185
2Acute necrotizing encephalopathy (HP:0006965)3.98769715
3Molar tooth sign on MRI (HP:0002419)3.85515965
4Abnormality of midbrain morphology (HP:0002418)3.85515965
5Abnormality of cells of the erythroid lineage (HP:0012130)3.81173817
6Pancreatic cysts (HP:0001737)3.65702550
7Mitochondrial inheritance (HP:0001427)3.63164561
8Nephronophthisis (HP:0000090)3.62063716
9Pancreatic fibrosis (HP:0100732)3.55997377
10Acute encephalopathy (HP:0006846)3.54960051
11Abnormal mitochondria in muscle tissue (HP:0008316)3.38682226
12Progressive macrocephaly (HP:0004481)3.26823252
13Increased CSF lactate (HP:0002490)3.22430505
143-Methylglutaconic aciduria (HP:0003535)3.17013885
15Type II lissencephaly (HP:0007260)3.12699021
16Abnormality of the renal medulla (HP:0100957)3.07445761
17Congenital stationary night blindness (HP:0007642)3.01538724
18Hepatocellular necrosis (HP:0001404)3.00193411
19Lipid accumulation in hepatocytes (HP:0006561)2.97436912
20Aplasia/Hypoplasia of the spleen (HP:0010451)2.94100157
21Dynein arm defect of respiratory motile cilia (HP:0012255)2.92911774
22Absent/shortened dynein arms (HP:0200106)2.92911774
23True hermaphroditism (HP:0010459)2.90964215
24Asplenia (HP:0001746)2.89939110
25Septo-optic dysplasia (HP:0100842)2.87325063
26Medial flaring of the eyebrow (HP:0010747)2.87110341
27Macrocytic anemia (HP:0001972)2.81857596
28Increased hepatocellular lipid droplets (HP:0006565)2.77773116
29Congenital, generalized hypertrichosis (HP:0004540)2.72404800
30Abnormal number of erythroid precursors (HP:0012131)2.66932820
31Optic disc pallor (HP:0000543)2.61252616
32Abnormal respiratory epithelium morphology (HP:0012253)2.59946628
33Abnormal respiratory motile cilium morphology (HP:0005938)2.59946628
34Methylmalonic acidemia (HP:0002912)2.55602973
35Abnormal rod and cone electroretinograms (HP:0008323)2.50842503
36Hepatic necrosis (HP:0002605)2.50429787
37Absent thumb (HP:0009777)2.48293235
38Supernumerary spleens (HP:0009799)2.48161329
39IgG deficiency (HP:0004315)2.48003685
40Absent rod-and cone-mediated responses on ERG (HP:0007688)2.42976270
41Elevated erythrocyte sedimentation rate (HP:0003565)2.36901879
42Abnormal ciliary motility (HP:0012262)2.33677688
43Sclerocornea (HP:0000647)2.33617943
44Cerebral edema (HP:0002181)2.33275815
45Cystic liver disease (HP:0006706)2.31918911
46Tubular atrophy (HP:0000092)2.30942758
47Stenosis of the external auditory canal (HP:0000402)2.25796936
48Abnormality of the renal cortex (HP:0011035)2.25233409
49Increased serum lactate (HP:0002151)2.23059689
50Abolished electroretinogram (ERG) (HP:0000550)2.21953000
51Pendular nystagmus (HP:0012043)2.18653735
52Type 2 muscle fiber atrophy (HP:0003554)2.18389001
53Renal Fanconi syndrome (HP:0001994)2.13973801
54Polydipsia (HP:0001959)2.12924439
55Abnormal drinking behavior (HP:0030082)2.12924439
56Pallor (HP:0000980)2.11291445
57Optic nerve hypoplasia (HP:0000609)2.08750586
58Gait imbalance (HP:0002141)2.07928361
59Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.07752765
60Abnormal respiratory motile cilium physiology (HP:0012261)2.07089135
61Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.06436454
62Rib fusion (HP:0000902)2.04227789
63Stomatitis (HP:0010280)2.04161252
64Abnormality of the labia minora (HP:0012880)2.03682704
65Colon cancer (HP:0003003)2.01562485
66Attenuation of retinal blood vessels (HP:0007843)2.01121663
67Congenital primary aphakia (HP:0007707)2.00270152
68Hypoplasia of the ulna (HP:0003022)1.99217516
69Growth hormone deficiency (HP:0000824)1.99065820
70Increased intramyocellular lipid droplets (HP:0012240)1.95346322
71Cerebellar dysplasia (HP:0007033)1.95208771
72Abnormality of the prostate (HP:0008775)1.94740503
73Testicular atrophy (HP:0000029)1.93566612
74Hyperglycinemia (HP:0002154)1.92475029
75Methylmalonic aciduria (HP:0012120)1.92292770
76Congenital hepatic fibrosis (HP:0002612)1.91724982
77Anencephaly (HP:0002323)1.91303213
78Postaxial foot polydactyly (HP:0001830)1.91070816
79Prostate neoplasm (HP:0100787)1.85483574
80Anterior segment dysgenesis (HP:0007700)1.85181973
81Decreased electroretinogram (ERG) amplitude (HP:0000654)1.83896235
82Nephrogenic diabetes insipidus (HP:0009806)1.83077833
83Lactic acidosis (HP:0003128)1.82085180
84Decreased central vision (HP:0007663)1.79703109
85Exertional dyspnea (HP:0002875)1.79606614
86Increased muscle lipid content (HP:0009058)1.78802856
87Maternal diabetes (HP:0009800)1.78424056
88Aplasia/Hypoplasia of the ulna (HP:0006495)1.77649804
89Polyuria (HP:0000103)1.76158811
90Lethargy (HP:0001254)1.75781785
91Leukodystrophy (HP:0002415)1.75740170
92Male pseudohermaphroditism (HP:0000037)1.73576878
93Muscle fiber atrophy (HP:0100295)1.73008800
94Chronic hepatic failure (HP:0100626)1.69336310
95Abnormality of the proximal phalanges of the hand (HP:0009834)1.68380490
96Porencephaly (HP:0002132)1.68170368
97Tubulointerstitial fibrosis (HP:0005576)1.67401030
98Abnormality of the pons (HP:0007361)1.67315978
99Hypoplasia of the radius (HP:0002984)1.66634148
100Hypoproteinemia (HP:0003075)1.65951856

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK13.94007978
2ZAK3.34673217
3STK163.03772275
4ADRBK22.90166796
5NUAK12.77275306
6WNK42.59737097
7TXK2.55045910
8FRK2.53229671
9GRK12.44921710
10TAOK32.41368829
11PINK12.36099335
12PIK3CA2.05399174
13MAP3K121.95086187
14DYRK21.89013245
15MAP4K21.85798785
16CDK191.85087326
17BCKDK1.71889592
18TIE11.51491725
19VRK21.42198524
20WNK31.38379731
21BMPR1B1.34002920
22PHKG21.25320910
23PHKG11.25320910
24DAPK21.15672983
25KIT1.09924891
26TRIM281.09649476
27CAMKK21.05440527
28EIF2AK31.05063000
29MAP4K11.04831874
30TEC1.03462574
31BTK1.03390855
32PRKCG1.02056591
33WNK11.01262650
34STK390.99233881
35IKBKB0.97773273
36PRKCQ0.94793511
37NEK10.93018176
38BMPR20.92408037
39FES0.91155391
40SYK0.90539809
41DAPK30.88426003
42ITK0.87581331
43ADRBK10.86259985
44LRRK20.85763156
45MYLK0.85134621
46INSRR0.84932285
47GRK70.77661494
48RPS6KA50.76504502
49EPHA40.75162124
50VRK10.73581248
51OXSR10.72205759
52NME10.71279579
53TGFBR10.67346592
54CDC70.67071858
55CAMK10.66930699
56AURKB0.66574756
57PRKCH0.65752743
58CSNK1G20.65461922
59PASK0.64736836
60EIF2AK10.62833392
61CDK80.60973120
62PRKACA0.60500172
63CAMKK10.59942934
64NTRK20.59465940
65MAPK130.55836409
66EIF2AK20.55402803
67PLK30.54712932
68OBSCN0.54488246
69CSNK2A20.54142249
70TNK20.54056107
71NME20.53586791
72CSNK1E0.51466795
73MAP2K20.51422519
74PRKCE0.50328333
75PAK30.50126445
76LYN0.50100232
77RPS6KA60.49464651
78ILK0.49271827
79ATR0.48584826
80CASK0.47414467
81PRKCA0.47335180
82GRK50.47312101
83FLT30.46562292
84TNIK0.46405795
85CAMK2A0.46298240
86CSNK1G30.46266005
87PRKCD0.45705105
88MAP3K40.45524839
89PLK20.43461659
90CSNK2A10.42599028
91PLK40.41085843
92CAMK2D0.41004539
93DAPK10.40824635
94GRK60.40395244
95PLK10.37227948
96CSNK1A10.36610857
97TYRO30.36107575
98STK110.35122294
99MAP2K60.34758873
100IGF1R0.34023618

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.87975405
2Oxidative phosphorylation_Homo sapiens_hsa001903.89913658
3Asthma_Homo sapiens_hsa053103.47776481
4Parkinsons disease_Homo sapiens_hsa050123.20497297
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.58876668
6Allograft rejection_Homo sapiens_hsa053302.52713599
7Proteasome_Homo sapiens_hsa030502.47295238
8Cardiac muscle contraction_Homo sapiens_hsa042602.29692033
9Autoimmune thyroid disease_Homo sapiens_hsa053202.29305545
10Protein export_Homo sapiens_hsa030602.27010047
11Graft-versus-host disease_Homo sapiens_hsa053322.26168601
12Alzheimers disease_Homo sapiens_hsa050102.21534028
13Huntingtons disease_Homo sapiens_hsa050162.13939193
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.05983129
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.02422761
16Type I diabetes mellitus_Homo sapiens_hsa049401.98128021
17Linoleic acid metabolism_Homo sapiens_hsa005911.93019184
18RNA polymerase_Homo sapiens_hsa030201.84961631
19Caffeine metabolism_Homo sapiens_hsa002321.70489015
20Homologous recombination_Homo sapiens_hsa034401.65781587
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.65214643
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.64525841
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.58823456
24Phototransduction_Homo sapiens_hsa047441.42417258
25RNA degradation_Homo sapiens_hsa030181.40492977
26Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.38147207
27One carbon pool by folate_Homo sapiens_hsa006701.30788532
28Fanconi anemia pathway_Homo sapiens_hsa034601.27244243
29Basal transcription factors_Homo sapiens_hsa030221.23960306
30Antigen processing and presentation_Homo sapiens_hsa046121.21624751
31Nucleotide excision repair_Homo sapiens_hsa034201.16837703
32Arachidonic acid metabolism_Homo sapiens_hsa005901.16648933
33Propanoate metabolism_Homo sapiens_hsa006401.15811530
34Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.09599713
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06233960
36Pyrimidine metabolism_Homo sapiens_hsa002401.05005718
37Nicotine addiction_Homo sapiens_hsa050331.03827934
38Sulfur relay system_Homo sapiens_hsa041221.03528243
39Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.01143566
40Ether lipid metabolism_Homo sapiens_hsa005651.00565468
41Nitrogen metabolism_Homo sapiens_hsa009101.00227869
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.99507453
43Tryptophan metabolism_Homo sapiens_hsa003800.98236225
44Chemical carcinogenesis_Homo sapiens_hsa052040.96384213
45Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95067912
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94933466
47Primary immunodeficiency_Homo sapiens_hsa053400.89760921
48Fat digestion and absorption_Homo sapiens_hsa049750.88859814
49Rheumatoid arthritis_Homo sapiens_hsa053230.88723223
50Butanoate metabolism_Homo sapiens_hsa006500.88600649
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88312329
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.87458421
53Mismatch repair_Homo sapiens_hsa034300.84790700
54Olfactory transduction_Homo sapiens_hsa047400.78529465
55Purine metabolism_Homo sapiens_hsa002300.77453771
56Peroxisome_Homo sapiens_hsa041460.69640909
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68946812
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68717190
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.65571378
60Morphine addiction_Homo sapiens_hsa050320.65286603
61Systemic lupus erythematosus_Homo sapiens_hsa053220.64668581
62Base excision repair_Homo sapiens_hsa034100.63529545
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62095637
64Metabolic pathways_Homo sapiens_hsa011000.61169371
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59162815
66Spliceosome_Homo sapiens_hsa030400.59030335
67DNA replication_Homo sapiens_hsa030300.58205080
68Staphylococcus aureus infection_Homo sapiens_hsa051500.57083771
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56591650
70Steroid hormone biosynthesis_Homo sapiens_hsa001400.55292251
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.54843244
72Regulation of autophagy_Homo sapiens_hsa041400.53060789
73Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52564513
74Retinol metabolism_Homo sapiens_hsa008300.48393235
75Taste transduction_Homo sapiens_hsa047420.47281095
76Cysteine and methionine metabolism_Homo sapiens_hsa002700.45879951
77Cyanoamino acid metabolism_Homo sapiens_hsa004600.45431222
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43241759
79Steroid biosynthesis_Homo sapiens_hsa001000.42902681
80Hematopoietic cell lineage_Homo sapiens_hsa046400.42019393
81Ovarian steroidogenesis_Homo sapiens_hsa049130.41921400
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41605768
83Folate biosynthesis_Homo sapiens_hsa007900.38325872
84Maturity onset diabetes of the young_Homo sapiens_hsa049500.37616687
85Viral myocarditis_Homo sapiens_hsa054160.36951900
86Serotonergic synapse_Homo sapiens_hsa047260.36831655
87GABAergic synapse_Homo sapiens_hsa047270.36646828
88RNA transport_Homo sapiens_hsa030130.36309970
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31188777
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30942026
91Non-homologous end-joining_Homo sapiens_hsa034500.29135083
92Primary bile acid biosynthesis_Homo sapiens_hsa001200.28675334
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.27015855
94Collecting duct acid secretion_Homo sapiens_hsa049660.26645466
95Hedgehog signaling pathway_Homo sapiens_hsa043400.24741430
96Fatty acid degradation_Homo sapiens_hsa000710.24308395
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23853041
98Insulin secretion_Homo sapiens_hsa049110.22709071
99Basal cell carcinoma_Homo sapiens_hsa052170.22636133
100Salivary secretion_Homo sapiens_hsa049700.20007875

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