

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.16744090 |
| 2 | maturation of SSU-rRNA (GO:0030490) | 7.12033780 |
| 3 | viral transcription (GO:0019083) | 6.80182345 |
| 4 | translational termination (GO:0006415) | 6.48072963 |
| 5 | ribosomal small subunit biogenesis (GO:0042274) | 6.19106686 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.84808113 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 5.80117273 |
| 8 | protein targeting to ER (GO:0045047) | 5.76991587 |
| 9 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.60675189 |
| 10 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.54238299 |
| 11 | translational elongation (GO:0006414) | 5.37838629 |
| 12 | protein localization to endoplasmic reticulum (GO:0070972) | 5.32061861 |
| 13 | viral life cycle (GO:0019058) | 4.90380483 |
| 14 | neuron fate determination (GO:0048664) | 4.88312917 |
| 15 | cellular protein complex disassembly (GO:0043624) | 4.85016856 |
| 16 | behavioral response to nicotine (GO:0035095) | 4.66729948 |
| 17 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.65384504 |
| 18 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.56143674 |
| 19 | kidney morphogenesis (GO:0060993) | 4.44246820 |
| 20 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 4.44105458 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.10516404 |
| 22 | protein complex disassembly (GO:0043241) | 4.08397504 |
| 23 | lens fiber cell development (GO:0070307) | 4.04091404 |
| 24 | chaperone-mediated protein transport (GO:0072321) | 4.03103812 |
| 25 | translational initiation (GO:0006413) | 3.98692164 |
| 26 | macromolecular complex disassembly (GO:0032984) | 3.84957480 |
| 27 | protein targeting to membrane (GO:0006612) | 3.83296715 |
| 28 | GTP biosynthetic process (GO:0006183) | 3.76728229 |
| 29 | lung epithelium development (GO:0060428) | 3.73580623 |
| 30 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.66712606 |
| 31 | high-density lipoprotein particle remodeling (GO:0034375) | 3.63256440 |
| 32 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.62348072 |
| 33 | regulation of centriole replication (GO:0046599) | 3.60122679 |
| 34 | adaptation of signaling pathway (GO:0023058) | 3.58876115 |
| 35 | ATP synthesis coupled proton transport (GO:0015986) | 3.55393577 |
| 36 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.55393577 |
| 37 | nonmotile primary cilium assembly (GO:0035058) | 3.55386812 |
| 38 | collecting duct development (GO:0072044) | 3.50343793 |
| 39 | glycerophospholipid catabolic process (GO:0046475) | 3.37694930 |
| 40 | protein neddylation (GO:0045116) | 3.35237974 |
| 41 | translation (GO:0006412) | 3.31957023 |
| 42 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.31880304 |
| 43 | ribosomal large subunit biogenesis (GO:0042273) | 3.30335494 |
| 44 | DNA strand renaturation (GO:0000733) | 3.30266576 |
| 45 | UTP biosynthetic process (GO:0006228) | 3.29471313 |
| 46 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.19848292 |
| 47 | regulation of cholesterol esterification (GO:0010872) | 3.19620458 |
| 48 | mRNA catabolic process (GO:0006402) | 3.18744006 |
| 49 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.16846866 |
| 50 | replication fork processing (GO:0031297) | 3.14118079 |
| 51 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.14027039 |
| 52 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.13527140 |
| 53 | central nervous system myelination (GO:0022010) | 3.12796346 |
| 54 | axon ensheathment in central nervous system (GO:0032291) | 3.12796346 |
| 55 | regulation of immunoglobulin secretion (GO:0051023) | 3.09978870 |
| 56 | centriole replication (GO:0007099) | 3.09524166 |
| 57 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.08034142 |
| 58 | somite development (GO:0061053) | 3.07197889 |
| 59 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.01589807 |
| 60 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.01589807 |
| 61 | NADH dehydrogenase complex assembly (GO:0010257) | 3.01589807 |
| 62 | cell proliferation in forebrain (GO:0021846) | 3.00530774 |
| 63 | UTP metabolic process (GO:0046051) | 2.97072804 |
| 64 | reverse cholesterol transport (GO:0043691) | 2.90843179 |
| 65 | respiratory tube development (GO:0030323) | 2.88684666 |
| 66 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.87890729 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.87890729 |
| 68 | intracellular protein transmembrane import (GO:0044743) | 2.84902272 |
| 69 | resolution of meiotic recombination intermediates (GO:0000712) | 2.83858260 |
| 70 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.83149342 |
| 71 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.82272989 |
| 72 | RNA catabolic process (GO:0006401) | 2.82259630 |
| 73 | cellular component biogenesis (GO:0044085) | 2.77972551 |
| 74 | plasma lipoprotein particle assembly (GO:0034377) | 2.77739755 |
| 75 | tongue development (GO:0043586) | 2.76782424 |
| 76 | amine catabolic process (GO:0009310) | 2.73380161 |
| 77 | cellular biogenic amine catabolic process (GO:0042402) | 2.73380161 |
| 78 | low-density lipoprotein particle remodeling (GO:0034374) | 2.73002749 |
| 79 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.71220835 |
| 80 | auditory receptor cell differentiation (GO:0042491) | 2.69973147 |
| 81 | regulation of regulatory T cell differentiation (GO:0045589) | 2.69642402 |
| 82 | protein complex biogenesis (GO:0070271) | 2.67173977 |
| 83 | glyoxylate metabolic process (GO:0046487) | 2.66397583 |
| 84 | nephron tubule morphogenesis (GO:0072078) | 2.64144964 |
| 85 | nephron epithelium morphogenesis (GO:0072088) | 2.64144964 |
| 86 | synaptic transmission, cholinergic (GO:0007271) | 2.63498295 |
| 87 | negative regulation of astrocyte differentiation (GO:0048712) | 2.63403047 |
| 88 | protein K6-linked ubiquitination (GO:0085020) | 2.61820982 |
| 89 | establishment of protein localization to membrane (GO:0090150) | 2.60683507 |
| 90 | lung morphogenesis (GO:0060425) | 2.59344783 |
| 91 | metanephric tubule development (GO:0072170) | 2.57760819 |
| 92 | metanephric nephron tubule development (GO:0072234) | 2.57760819 |
| 93 | cilium morphogenesis (GO:0060271) | 2.54567183 |
| 94 | protein targeting (GO:0006605) | 2.50004028 |
| 95 | lung-associated mesenchyme development (GO:0060484) | 2.49803249 |
| 96 | radial glial cell differentiation (GO:0060019) | 2.49305824 |
| 97 | negative regulation of organelle assembly (GO:1902116) | 2.48002997 |
| 98 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 2.47342250 |
| 99 | 4-hydroxyproline metabolic process (GO:0019471) | 2.47017632 |
| 100 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.46972618 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.41158551 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.39632390 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.84835326 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.80275522 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.61896520 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.53867654 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51990331 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34368560 |
| 9 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.29800671 |
| 10 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.24034525 |
| 11 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.19721638 |
| 12 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.15915535 |
| 13 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.09434158 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.01665768 |
| 15 | FUS_26573619_Chip-Seq_HEK293_Human | 1.91913620 |
| 16 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.89080814 |
| 17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.89035900 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 1.88788604 |
| 19 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.84781527 |
| 20 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.79074210 |
| 21 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.76881857 |
| 22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.72285159 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.63992764 |
| 24 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.62630116 |
| 25 | P300_19829295_ChIP-Seq_ESCs_Human | 1.51873404 |
| 26 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.51350150 |
| 27 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.48431292 |
| 28 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.47788911 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.46773989 |
| 30 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.45677723 |
| 31 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.45125976 |
| 32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.43426668 |
| 33 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.41961151 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.41900273 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40969816 |
| 36 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.40755340 |
| 37 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.39131872 |
| 38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.37839419 |
| 39 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.37440553 |
| 40 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.36901095 |
| 41 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.35680946 |
| 42 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.33326821 |
| 43 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.32063225 |
| 44 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.31719220 |
| 45 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.30317258 |
| 46 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.27933358 |
| 47 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.27041758 |
| 48 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.26591739 |
| 49 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.26414738 |
| 50 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.23716062 |
| 51 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.21228145 |
| 52 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20620623 |
| 53 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.20064452 |
| 54 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.19322668 |
| 55 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.18438733 |
| 56 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.18335271 |
| 57 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.16789199 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16121181 |
| 59 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.16040966 |
| 60 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.15391435 |
| 61 | ERA_21632823_ChIP-Seq_H3396_Human | 1.14629247 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.12866821 |
| 63 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12518023 |
| 64 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12518023 |
| 65 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.12183143 |
| 66 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.12183143 |
| 67 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.11802996 |
| 68 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.11776958 |
| 69 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.11548374 |
| 70 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.10414794 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.10227380 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.10227380 |
| 73 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.09409551 |
| 74 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.09245703 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07415490 |
| 76 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.05957717 |
| 77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.05406464 |
| 78 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03436934 |
| 79 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.02870188 |
| 80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.02379518 |
| 81 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.01992748 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99636428 |
| 83 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.98665140 |
| 84 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.98088080 |
| 85 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.97917558 |
| 86 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.97539715 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96532439 |
| 88 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.96187726 |
| 89 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95981618 |
| 90 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.95757235 |
| 91 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.95571602 |
| 92 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94554650 |
| 93 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.94011812 |
| 94 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.94011224 |
| 95 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.92725547 |
| 96 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.92660805 |
| 97 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.91267078 |
| 98 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91146127 |
| 99 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91146127 |
| 100 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.90285208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.99713191 |
| 2 | MP0010030_abnormal_orbit_morphology | 4.81193309 |
| 3 | MP0006292_abnormal_olfactory_placode | 4.07600604 |
| 4 | MP0000604_amyloidosis | 2.65643741 |
| 5 | MP0002102_abnormal_ear_morphology | 2.64650802 |
| 6 | MP0005377_hearing/vestibular/ear_phenot | 2.43594884 |
| 7 | MP0003878_abnormal_ear_physiology | 2.43594884 |
| 8 | MP0001293_anophthalmia | 2.28607293 |
| 9 | MP0008789_abnormal_olfactory_epithelium | 2.21976012 |
| 10 | MP0005408_hypopigmentation | 2.20739768 |
| 11 | MP0001485_abnormal_pinna_reflex | 2.17405279 |
| 12 | MP0001986_abnormal_taste_sensitivity | 2.15583698 |
| 13 | MP0002234_abnormal_pharynx_morphology | 2.14598153 |
| 14 | MP0002938_white_spotting | 2.08007011 |
| 15 | MP0004133_heterotaxia | 2.01896997 |
| 16 | MP0002638_abnormal_pupillary_reflex | 1.94579430 |
| 17 | MP0005394_taste/olfaction_phenotype | 1.92955490 |
| 18 | MP0005499_abnormal_olfactory_system | 1.92955490 |
| 19 | MP0000049_abnormal_middle_ear | 1.89587629 |
| 20 | MP0003122_maternal_imprinting | 1.84694124 |
| 21 | MP0008872_abnormal_physiological_respon | 1.77015323 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.76913942 |
| 23 | MP0003136_yellow_coat_color | 1.76356489 |
| 24 | MP0005646_abnormal_pituitary_gland | 1.72404363 |
| 25 | MP0001346_abnormal_lacrimal_gland | 1.71775635 |
| 26 | MP0000026_abnormal_inner_ear | 1.66232275 |
| 27 | MP0001984_abnormal_olfaction | 1.65270937 |
| 28 | MP0004142_abnormal_muscle_tone | 1.63151711 |
| 29 | MP0003646_muscle_fatigue | 1.62694750 |
| 30 | MP0002736_abnormal_nociception_after | 1.60684407 |
| 31 | MP0004885_abnormal_endolymph | 1.60091041 |
| 32 | MP0005248_abnormal_Harderian_gland | 1.59962437 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.58210972 |
| 34 | MP0003123_paternal_imprinting | 1.53104726 |
| 35 | MP0002653_abnormal_ependyma_morphology | 1.50048326 |
| 36 | MP0004742_abnormal_vestibular_system | 1.44777378 |
| 37 | MP0000566_synostosis | 1.44221851 |
| 38 | MP0003937_abnormal_limbs/digits/tail_de | 1.42674796 |
| 39 | MP0003938_abnormal_ear_development | 1.37174753 |
| 40 | MP0005423_abnormal_somatic_nervous | 1.36805808 |
| 41 | MP0002138_abnormal_hepatobiliary_system | 1.36507144 |
| 42 | MP0001968_abnormal_touch/_nociception | 1.35833360 |
| 43 | MP0005084_abnormal_gallbladder_morpholo | 1.29750790 |
| 44 | MP0002272_abnormal_nervous_system | 1.29115833 |
| 45 | MP0003880_abnormal_central_pattern | 1.28916675 |
| 46 | MP0003693_abnormal_embryo_hatching | 1.28174621 |
| 47 | MP0003718_maternal_effect | 1.28011911 |
| 48 | MP0002095_abnormal_skin_pigmentation | 1.25100492 |
| 49 | MP0000778_abnormal_nervous_system | 1.25050470 |
| 50 | MP0003121_genomic_imprinting | 1.21921913 |
| 51 | MP0005195_abnormal_posterior_eye | 1.14419008 |
| 52 | MP0000631_abnormal_neuroendocrine_gland | 1.12663992 |
| 53 | MP0001286_abnormal_eye_development | 1.10882040 |
| 54 | MP0001963_abnormal_hearing_physiology | 1.10551176 |
| 55 | MP0001486_abnormal_startle_reflex | 1.09328355 |
| 56 | MP0003011_delayed_dark_adaptation | 1.08596076 |
| 57 | MP0009384_cardiac_valve_regurgitation | 1.07382957 |
| 58 | MP0003119_abnormal_digestive_system | 1.03557109 |
| 59 | MP0003786_premature_aging | 1.02316591 |
| 60 | MP0002752_abnormal_somatic_nervous | 1.01975884 |
| 61 | MP0003936_abnormal_reproductive_system | 0.99616315 |
| 62 | MP0001348_abnormal_lacrimal_gland | 0.99003960 |
| 63 | MP0003879_abnormal_hair_cell | 0.98824944 |
| 64 | MP0003329_amyloid_beta_deposits | 0.98737400 |
| 65 | MP0005391_vision/eye_phenotype | 0.98496400 |
| 66 | MP0002233_abnormal_nose_morphology | 0.97862890 |
| 67 | MP0002184_abnormal_innervation | 0.95532340 |
| 68 | MP0004145_abnormal_muscle_electrophysio | 0.93646257 |
| 69 | MP0002697_abnormal_eye_size | 0.92378183 |
| 70 | MP0008875_abnormal_xenobiotic_pharmacok | 0.91008095 |
| 71 | MP0003567_abnormal_fetal_cardiomyocyte | 0.90636046 |
| 72 | MP0002210_abnormal_sex_determination | 0.89859475 |
| 73 | MP0006276_abnormal_autonomic_nervous | 0.89558144 |
| 74 | MP0003283_abnormal_digestive_organ | 0.85685772 |
| 75 | MP0001440_abnormal_grooming_behavior | 0.84617573 |
| 76 | MP0002092_abnormal_eye_morphology | 0.82911504 |
| 77 | MP0002557_abnormal_social/conspecific_i | 0.82837362 |
| 78 | MP0001529_abnormal_vocalization | 0.78740146 |
| 79 | MP0005253_abnormal_eye_physiology | 0.77744711 |
| 80 | MP0002277_abnormal_respiratory_mucosa | 0.77204736 |
| 81 | MP0001119_abnormal_female_reproductive | 0.76774073 |
| 82 | MP0006072_abnormal_retinal_apoptosis | 0.75528959 |
| 83 | MP0009745_abnormal_behavioral_response | 0.74734317 |
| 84 | MP0001324_abnormal_eye_pigmentation | 0.73738748 |
| 85 | MP0002249_abnormal_larynx_morphology | 0.73544462 |
| 86 | MP0000428_abnormal_craniofacial_morphol | 0.72261564 |
| 87 | MP0000372_irregular_coat_pigmentation | 0.70923809 |
| 88 | MP0001502_abnormal_circadian_rhythm | 0.70240437 |
| 89 | MP0002282_abnormal_trachea_morphology | 0.68135662 |
| 90 | MP0002735_abnormal_chemical_nociception | 0.68003324 |
| 91 | MP0009053_abnormal_anal_canal | 0.67380560 |
| 92 | MP0010329_abnormal_lipoprotein_level | 0.66486265 |
| 93 | MP0003755_abnormal_palate_morphology | 0.66079080 |
| 94 | MP0002116_abnormal_craniofacial_bone | 0.65747656 |
| 95 | MP0010094_abnormal_chromosome_stability | 0.65576157 |
| 96 | MP0001299_abnormal_eye_distance/ | 0.65138485 |
| 97 | MP0002111_abnormal_tail_morphology | 0.62925367 |
| 98 | MP0002876_abnormal_thyroid_physiology | 0.62419873 |
| 99 | MP0003861_abnormal_nervous_system | 0.62117155 |
| 100 | MP0002928_abnormal_bile_duct | 0.60261924 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 5.84607571 |
| 2 | Reticulocytopenia (HP:0001896) | 4.93276794 |
| 3 | Type II lissencephaly (HP:0007260) | 3.46711306 |
| 4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.25139787 |
| 5 | Maternal diabetes (HP:0009800) | 3.24282073 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 3.23804895 |
| 7 | Molar tooth sign on MRI (HP:0002419) | 3.23804895 |
| 8 | Cerebellar dysplasia (HP:0007033) | 2.97360864 |
| 9 | Abnormality of the labia minora (HP:0012880) | 2.91975622 |
| 10 | Myelomeningocele (HP:0002475) | 2.91497942 |
| 11 | Bile duct proliferation (HP:0001408) | 2.81873540 |
| 12 | Abnormal biliary tract physiology (HP:0012439) | 2.81873540 |
| 13 | Abnormality of the pons (HP:0007361) | 2.81191015 |
| 14 | Meningocele (HP:0002435) | 2.78454514 |
| 15 | Anencephaly (HP:0002323) | 2.76565290 |
| 16 | Pancreatic cysts (HP:0001737) | 2.74390761 |
| 17 | Pancreatic fibrosis (HP:0100732) | 2.72891690 |
| 18 | Septo-optic dysplasia (HP:0100842) | 2.72321055 |
| 19 | Partial duplication of thumb phalanx (HP:0009944) | 2.62419254 |
| 20 | Macrocytic anemia (HP:0001972) | 2.62102876 |
| 21 | Bifid tongue (HP:0010297) | 2.61629191 |
| 22 | Acute necrotizing encephalopathy (HP:0006965) | 2.61539205 |
| 23 | Hypoplasia of the pons (HP:0012110) | 2.59831360 |
| 24 | Anophthalmia (HP:0000528) | 2.57274728 |
| 25 | True hermaphroditism (HP:0010459) | 2.45822866 |
| 26 | Nephronophthisis (HP:0000090) | 2.45698193 |
| 27 | Chronic hepatic failure (HP:0100626) | 2.43856441 |
| 28 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.41457718 |
| 29 | Morphological abnormality of the middle ear (HP:0008609) | 2.39669613 |
| 30 | Ectopic kidney (HP:0000086) | 2.36494030 |
| 31 | Absent thumb (HP:0009777) | 2.33106228 |
| 32 | Hepatoblastoma (HP:0002884) | 2.31713028 |
| 33 | Acute encephalopathy (HP:0006846) | 2.30402189 |
| 34 | Hyperglycinemia (HP:0002154) | 2.29774449 |
| 35 | Pendular nystagmus (HP:0012043) | 2.28877927 |
| 36 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.27472714 |
| 37 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.26071414 |
| 38 | Abnormality of alanine metabolism (HP:0010916) | 2.25402169 |
| 39 | Hyperalaninemia (HP:0003348) | 2.25402169 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.25402169 |
| 41 | Oligodactyly (hands) (HP:0001180) | 2.24772111 |
| 42 | Rib fusion (HP:0000902) | 2.23150616 |
| 43 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.21020326 |
| 44 | Hypoplasia of the radius (HP:0002984) | 2.20344301 |
| 45 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.20174261 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.19004744 |
| 47 | Abnormality of the renal medulla (HP:0100957) | 2.18842899 |
| 48 | Stenosis of the external auditory canal (HP:0000402) | 2.17300768 |
| 49 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.16863791 |
| 50 | Abnormal ciliary motility (HP:0012262) | 2.16390691 |
| 51 | Horseshoe kidney (HP:0000085) | 2.14869535 |
| 52 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.14269094 |
| 53 | Asplenia (HP:0001746) | 2.13817447 |
| 54 | Supernumerary spleens (HP:0009799) | 2.13441762 |
| 55 | Drooling (HP:0002307) | 2.11593430 |
| 56 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.11308393 |
| 57 | Chorioretinal atrophy (HP:0000533) | 2.10019456 |
| 58 | Triphalangeal thumb (HP:0001199) | 2.09977403 |
| 59 | Failure to thrive in infancy (HP:0001531) | 2.09659899 |
| 60 | Stomatitis (HP:0010280) | 2.08790347 |
| 61 | Partial duplication of the phalanx of hand (HP:0009999) | 2.07225782 |
| 62 | Absent septum pellucidum (HP:0001331) | 2.06450739 |
| 63 | Osteomalacia (HP:0002749) | 2.05562841 |
| 64 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.01817983 |
| 65 | High anterior hairline (HP:0009890) | 1.98895365 |
| 66 | Depressed nasal ridge (HP:0000457) | 1.98208325 |
| 67 | Cystic liver disease (HP:0006706) | 1.97352214 |
| 68 | Progressive macrocephaly (HP:0004481) | 1.96832052 |
| 69 | Anterior segment dysgenesis (HP:0007700) | 1.96426054 |
| 70 | Cutaneous finger syndactyly (HP:0010554) | 1.96065717 |
| 71 | Dyschromatopsia (HP:0007641) | 1.95285812 |
| 72 | Intestinal atresia (HP:0011100) | 1.94702247 |
| 73 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.94141653 |
| 74 | Severe muscular hypotonia (HP:0006829) | 1.92877047 |
| 75 | Abnormality of incisor morphology (HP:0011063) | 1.92688532 |
| 76 | Excessive salivation (HP:0003781) | 1.92064324 |
| 77 | Holoprosencephaly (HP:0001360) | 1.91615490 |
| 78 | Cutaneous syndactyly (HP:0012725) | 1.91218994 |
| 79 | Pallor (HP:0000980) | 1.89788025 |
| 80 | Medial flaring of the eyebrow (HP:0010747) | 1.89274570 |
| 81 | Dandy-Walker malformation (HP:0001305) | 1.86388203 |
| 82 | Oligodactyly (HP:0012165) | 1.86188143 |
| 83 | Meckel diverticulum (HP:0002245) | 1.85736595 |
| 84 | Thyroid-stimulating hormone excess (HP:0002925) | 1.85729628 |
| 85 | Optic disc pallor (HP:0000543) | 1.85273664 |
| 86 | Enlarged kidneys (HP:0000105) | 1.84197913 |
| 87 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.83895181 |
| 88 | Hypoplasia of the ulna (HP:0003022) | 1.83517214 |
| 89 | Sclerocornea (HP:0000647) | 1.81643883 |
| 90 | Bilateral microphthalmos (HP:0007633) | 1.78585429 |
| 91 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.78573739 |
| 92 | Labial hypoplasia (HP:0000066) | 1.77612338 |
| 93 | Vitreoretinal degeneration (HP:0000655) | 1.77341034 |
| 94 | Forearm undergrowth (HP:0009821) | 1.77040228 |
| 95 | Hypoplastic female external genitalia (HP:0012815) | 1.75418084 |
| 96 | Lissencephaly (HP:0001339) | 1.75076771 |
| 97 | Narrow forehead (HP:0000341) | 1.74261769 |
| 98 | Congenital stationary night blindness (HP:0007642) | 1.73621950 |
| 99 | Abnormality of the ileum (HP:0001549) | 1.72883299 |
| 100 | Vaginal atresia (HP:0000148) | 1.72276733 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 3.14439025 |
| 2 | TRIM28 | 2.82773248 |
| 3 | CDC7 | 2.64005826 |
| 4 | MAP3K4 | 2.58951369 |
| 5 | PLK4 | 2.56323723 |
| 6 | PDK2 | 2.52254433 |
| 7 | ADRBK2 | 2.46768710 |
| 8 | TNIK | 2.45192494 |
| 9 | STK39 | 2.35444641 |
| 10 | OBSCN | 2.19395315 |
| 11 | WNK3 | 2.02677219 |
| 12 | MAP4K2 | 2.00282496 |
| 13 | EPHB2 | 1.99283655 |
| 14 | CASK | 1.96170269 |
| 15 | GRK1 | 1.85192331 |
| 16 | DYRK2 | 1.84795343 |
| 17 | PIK3CA | 1.80966536 |
| 18 | ZAK | 1.70273283 |
| 19 | PLK2 | 1.69409509 |
| 20 | FRK | 1.63219917 |
| 21 | TLK1 | 1.57671878 |
| 22 | NME1 | 1.52664021 |
| 23 | LRRK2 | 1.50111140 |
| 24 | CAMK1 | 1.49288116 |
| 25 | OXSR1 | 1.44332975 |
| 26 | WNK1 | 1.39864648 |
| 27 | TAF1 | 1.38733229 |
| 28 | TXK | 1.36168989 |
| 29 | TIE1 | 1.32564808 |
| 30 | INSRR | 1.30279108 |
| 31 | BCKDK | 1.29797854 |
| 32 | EPHA3 | 1.26759357 |
| 33 | NUAK1 | 1.19193712 |
| 34 | PRKCH | 1.17761559 |
| 35 | PRKCG | 1.17667681 |
| 36 | PINK1 | 1.14313020 |
| 37 | DAPK3 | 1.11865112 |
| 38 | FGFR2 | 1.09900998 |
| 39 | PAK3 | 1.09882693 |
| 40 | MAP3K12 | 1.06585714 |
| 41 | DAPK2 | 1.06542018 |
| 42 | MAP2K4 | 1.00124856 |
| 43 | ADRBK1 | 0.94035790 |
| 44 | PNCK | 0.90816163 |
| 45 | CAMK4 | 0.88769766 |
| 46 | VRK2 | 0.88456549 |
| 47 | TGFBR1 | 0.86913553 |
| 48 | STK16 | 0.85103792 |
| 49 | ATR | 0.83371510 |
| 50 | PASK | 0.76920393 |
| 51 | AURKB | 0.76806323 |
| 52 | STK11 | 0.76193241 |
| 53 | BUB1 | 0.72148635 |
| 54 | CSNK2A2 | 0.71823287 |
| 55 | MAPKAPK5 | 0.70841708 |
| 56 | PRKCQ | 0.69506418 |
| 57 | FGFR1 | 0.68967968 |
| 58 | PRKCI | 0.67575313 |
| 59 | WEE1 | 0.64682924 |
| 60 | CAMK1G | 0.64379394 |
| 61 | CDK19 | 0.63433376 |
| 62 | PHKG1 | 0.63305282 |
| 63 | PHKG2 | 0.63305282 |
| 64 | AURKA | 0.63280035 |
| 65 | MARK3 | 0.61965357 |
| 66 | NME2 | 0.61682071 |
| 67 | VRK1 | 0.61192957 |
| 68 | MAP2K7 | 0.61024673 |
| 69 | CAMK1D | 0.60611521 |
| 70 | BMPR1B | 0.60533437 |
| 71 | CAMK2A | 0.60518907 |
| 72 | PRKACA | 0.60312731 |
| 73 | PRKCE | 0.58611197 |
| 74 | SRPK1 | 0.55180073 |
| 75 | PIK3CG | 0.54948918 |
| 76 | MARK1 | 0.53348794 |
| 77 | PRKCA | 0.52812829 |
| 78 | MAPK13 | 0.50819863 |
| 79 | CDK8 | 0.50107605 |
| 80 | PLK3 | 0.49571444 |
| 81 | STK3 | 0.49326044 |
| 82 | PLK1 | 0.49204218 |
| 83 | RPS6KA6 | 0.48944746 |
| 84 | ATM | 0.48305978 |
| 85 | NTRK2 | 0.47932519 |
| 86 | CAMK2D | 0.47140363 |
| 87 | CSNK2A1 | 0.46332904 |
| 88 | CSNK1G2 | 0.45299566 |
| 89 | CAMKK2 | 0.45045295 |
| 90 | MKNK1 | 0.44622239 |
| 91 | TEC | 0.44003907 |
| 92 | PRKDC | 0.43365247 |
| 93 | CSNK1E | 0.43062090 |
| 94 | CAMK2B | 0.42977137 |
| 95 | PIM1 | 0.41809440 |
| 96 | MAP2K6 | 0.41034153 |
| 97 | DAPK1 | 0.40452653 |
| 98 | MAPKAPK3 | 0.36790610 |
| 99 | ERBB4 | 0.36523715 |
| 100 | CSNK1G1 | 0.35322340 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.63132205 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.91035016 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.09138878 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.63437972 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.55494788 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.36131247 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.33592702 |
| 8 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.15615357 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.06253927 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.03422943 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.00890850 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 1.83180655 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.80474635 |
| 14 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.77789724 |
| 15 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.74317478 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.73169251 |
| 17 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.66438897 |
| 18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.64019306 |
| 19 | Proteasome_Homo sapiens_hsa03050 | 1.61637097 |
| 20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.61319108 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.56810004 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.55563515 |
| 23 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.54250761 |
| 24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.51509082 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.47764154 |
| 26 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.40755569 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.37484632 |
| 28 | Alzheimers disease_Homo sapiens_hsa05010 | 1.36070695 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.33999794 |
| 30 | Nicotine addiction_Homo sapiens_hsa05033 | 1.30810260 |
| 31 | Asthma_Homo sapiens_hsa05310 | 1.30272037 |
| 32 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.27719009 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.25955729 |
| 34 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.24616528 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.23144520 |
| 36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.16665982 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.16384836 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13936922 |
| 39 | DNA replication_Homo sapiens_hsa03030 | 1.13163018 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.09699940 |
| 41 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.09140897 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.08705984 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08675721 |
| 44 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.07304699 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.06874571 |
| 46 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.05360503 |
| 47 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.02533989 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01278989 |
| 49 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.92264592 |
| 50 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.90358444 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.88733444 |
| 52 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.86320140 |
| 53 | Base excision repair_Homo sapiens_hsa03410 | 0.82668830 |
| 54 | Morphine addiction_Homo sapiens_hsa05032 | 0.77485521 |
| 55 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.76940971 |
| 56 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.76415983 |
| 57 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.75403619 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.75148989 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72855229 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.71821594 |
| 61 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.67025519 |
| 62 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.66968626 |
| 63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63802342 |
| 64 | Insulin secretion_Homo sapiens_hsa04911 | 0.63159356 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61517100 |
| 66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.60026007 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.59479260 |
| 68 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.58692050 |
| 69 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58680351 |
| 70 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.57374182 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.55108944 |
| 72 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.47334249 |
| 73 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.47011650 |
| 74 | RNA transport_Homo sapiens_hsa03013 | 0.42279021 |
| 75 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.41566793 |
| 76 | Allograft rejection_Homo sapiens_hsa05330 | 0.41153165 |
| 77 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.41111918 |
| 78 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.38862564 |
| 79 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.38795499 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.37981619 |
| 81 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.37238598 |
| 82 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.36623553 |
| 83 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.35861118 |
| 84 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.34710654 |
| 85 | GABAergic synapse_Homo sapiens_hsa04727 | 0.33062951 |
| 86 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.33007069 |
| 87 | Salivary secretion_Homo sapiens_hsa04970 | 0.32115653 |
| 88 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.31961492 |
| 89 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.31221966 |
| 90 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.30166643 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.30005110 |
| 92 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.28939036 |
| 93 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.28285884 |
| 94 | Sulfur relay system_Homo sapiens_hsa04122 | 0.28203936 |
| 95 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.28052984 |
| 96 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.27059263 |
| 97 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.26938704 |
| 98 | Galactose metabolism_Homo sapiens_hsa00052 | 0.25970277 |
| 99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.25850818 |
| 100 | Melanogenesis_Homo sapiens_hsa04916 | 0.25799353 |

