RPL7P29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.16744090
2maturation of SSU-rRNA (GO:0030490)7.12033780
3viral transcription (GO:0019083)6.80182345
4translational termination (GO:0006415)6.48072963
5ribosomal small subunit biogenesis (GO:0042274)6.19106686
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.84808113
7cotranslational protein targeting to membrane (GO:0006613)5.80117273
8protein targeting to ER (GO:0045047)5.76991587
9establishment of protein localization to endoplasmic reticulum (GO:0072599)5.60675189
10positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)5.54238299
11translational elongation (GO:0006414)5.37838629
12protein localization to endoplasmic reticulum (GO:0070972)5.32061861
13viral life cycle (GO:0019058)4.90380483
14neuron fate determination (GO:0048664)4.88312917
15cellular protein complex disassembly (GO:0043624)4.85016856
16behavioral response to nicotine (GO:0035095)4.66729948
17regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)4.65384504
18nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.56143674
19kidney morphogenesis (GO:0060993)4.44246820
20triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.44105458
21establishment of protein localization to mitochondrial membrane (GO:0090151)4.10516404
22protein complex disassembly (GO:0043241)4.08397504
23lens fiber cell development (GO:0070307)4.04091404
24chaperone-mediated protein transport (GO:0072321)4.03103812
25translational initiation (GO:0006413)3.98692164
26macromolecular complex disassembly (GO:0032984)3.84957480
27protein targeting to membrane (GO:0006612)3.83296715
28GTP biosynthetic process (GO:0006183)3.76728229
29lung epithelium development (GO:0060428)3.73580623
30detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.66712606
31high-density lipoprotein particle remodeling (GO:0034375)3.63256440
32epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.62348072
33regulation of centriole replication (GO:0046599)3.60122679
34adaptation of signaling pathway (GO:0023058)3.58876115
35ATP synthesis coupled proton transport (GO:0015986)3.55393577
36energy coupled proton transport, down electrochemical gradient (GO:0015985)3.55393577
37nonmotile primary cilium assembly (GO:0035058)3.55386812
38collecting duct development (GO:0072044)3.50343793
39glycerophospholipid catabolic process (GO:0046475)3.37694930
40protein neddylation (GO:0045116)3.35237974
41translation (GO:0006412)3.31957023
42nuclear-transcribed mRNA catabolic process (GO:0000956)3.31880304
43ribosomal large subunit biogenesis (GO:0042273)3.30335494
44DNA strand renaturation (GO:0000733)3.30266576
45UTP biosynthetic process (GO:0006228)3.29471313
46regulation of cytokine secretion involved in immune response (GO:0002739)3.19848292
47regulation of cholesterol esterification (GO:0010872)3.19620458
48mRNA catabolic process (GO:0006402)3.18744006
49regulation of non-canonical Wnt signaling pathway (GO:2000050)3.16846866
50replication fork processing (GO:0031297)3.14118079
51mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.14027039
52ribonucleoprotein complex biogenesis (GO:0022613)3.13527140
53central nervous system myelination (GO:0022010)3.12796346
54axon ensheathment in central nervous system (GO:0032291)3.12796346
55regulation of immunoglobulin secretion (GO:0051023)3.09978870
56centriole replication (GO:0007099)3.09524166
57positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.08034142
58somite development (GO:0061053)3.07197889
59mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.01589807
60mitochondrial respiratory chain complex I assembly (GO:0032981)3.01589807
61NADH dehydrogenase complex assembly (GO:0010257)3.01589807
62cell proliferation in forebrain (GO:0021846)3.00530774
63UTP metabolic process (GO:0046051)2.97072804
64reverse cholesterol transport (GO:0043691)2.90843179
65respiratory tube development (GO:0030323)2.88684666
66RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.87890729
67tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.87890729
68intracellular protein transmembrane import (GO:0044743)2.84902272
69resolution of meiotic recombination intermediates (GO:0000712)2.83858260
70regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.83149342
71regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.82272989
72RNA catabolic process (GO:0006401)2.82259630
73cellular component biogenesis (GO:0044085)2.77972551
74plasma lipoprotein particle assembly (GO:0034377)2.77739755
75tongue development (GO:0043586)2.76782424
76amine catabolic process (GO:0009310)2.73380161
77cellular biogenic amine catabolic process (GO:0042402)2.73380161
78low-density lipoprotein particle remodeling (GO:0034374)2.73002749
79regulation of isotype switching to IgG isotypes (GO:0048302)2.71220835
80auditory receptor cell differentiation (GO:0042491)2.69973147
81regulation of regulatory T cell differentiation (GO:0045589)2.69642402
82protein complex biogenesis (GO:0070271)2.67173977
83glyoxylate metabolic process (GO:0046487)2.66397583
84nephron tubule morphogenesis (GO:0072078)2.64144964
85nephron epithelium morphogenesis (GO:0072088)2.64144964
86synaptic transmission, cholinergic (GO:0007271)2.63498295
87negative regulation of astrocyte differentiation (GO:0048712)2.63403047
88protein K6-linked ubiquitination (GO:0085020)2.61820982
89establishment of protein localization to membrane (GO:0090150)2.60683507
90lung morphogenesis (GO:0060425)2.59344783
91metanephric tubule development (GO:0072170)2.57760819
92metanephric nephron tubule development (GO:0072234)2.57760819
93cilium morphogenesis (GO:0060271)2.54567183
94protein targeting (GO:0006605)2.50004028
95lung-associated mesenchyme development (GO:0060484)2.49803249
96radial glial cell differentiation (GO:0060019)2.49305824
97negative regulation of organelle assembly (GO:1902116)2.48002997
98regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.47342250
994-hydroxyproline metabolic process (GO:0019471)2.47017632
100positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.46972618

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.41158551
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.39632390
3ZNF274_21170338_ChIP-Seq_K562_Hela2.84835326
4GABP_17652178_ChIP-ChIP_JURKAT_Human2.80275522
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.61896520
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.53867654
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.51990331
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.34368560
9E2F7_22180533_ChIP-Seq_HELA_Human2.29800671
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.24034525
11RBPJ_22232070_ChIP-Seq_NCS_Mouse2.19721638
12IRF1_19129219_ChIP-ChIP_H3396_Human2.15915535
13MYC_18940864_ChIP-ChIP_HL60_Human2.09434158
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.01665768
15FUS_26573619_Chip-Seq_HEK293_Human1.91913620
16GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.89080814
17TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.89035900
18VDR_22108803_ChIP-Seq_LS180_Human1.88788604
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.84781527
20GBX2_23144817_ChIP-Seq_PC3_Human1.79074210
21AUTS2_25519132_ChIP-Seq_293T-REX_Human1.76881857
22EZH2_27304074_Chip-Seq_ESCs_Mouse1.72285159
23EWS_26573619_Chip-Seq_HEK293_Human1.63992764
24RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.62630116
25P300_19829295_ChIP-Seq_ESCs_Human1.51873404
26MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.51350150
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.48431292
28ETV2_25802403_ChIP-Seq_MESCs_Mouse1.47788911
29TP53_22573176_ChIP-Seq_HFKS_Human1.46773989
30GATA1_26923725_Chip-Seq_HPCs_Mouse1.45677723
31GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.45125976
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43426668
33ETS1_20019798_ChIP-Seq_JURKAT_Human1.41961151
34NOTCH1_21737748_ChIP-Seq_TLL_Human1.41900273
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.40969816
36EST1_17652178_ChIP-ChIP_JURKAT_Human1.40755340
37BCAT_22108803_ChIP-Seq_LS180_Human1.39131872
38NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.37839419
39JARID2_20064375_ChIP-Seq_MESCs_Mouse1.37440553
40JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.36901095
41MYC_18555785_ChIP-Seq_MESCs_Mouse1.35680946
42UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33326821
43TAF15_26573619_Chip-Seq_HEK293_Human1.32063225
44GATA3_21878914_ChIP-Seq_MCF-7_Human1.31719220
45CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.30317258
46SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.27933358
47ELK1_19687146_ChIP-ChIP_HELA_Human1.27041758
48KLF5_20875108_ChIP-Seq_MESCs_Mouse1.26591739
49BMI1_23680149_ChIP-Seq_NPCS_Mouse1.26414738
50P53_22127205_ChIP-Seq_FIBROBLAST_Human1.23716062
51RNF2_27304074_Chip-Seq_ESCs_Mouse1.21228145
52TTF2_22483619_ChIP-Seq_HELA_Human1.20620623
53REST_21632747_ChIP-Seq_MESCs_Mouse1.20064452
54EED_16625203_ChIP-ChIP_MESCs_Mouse1.19322668
55TDRD3_21172665_ChIP-Seq_MCF-7_Human1.18438733
56SUZ12_27294783_Chip-Seq_ESCs_Mouse1.18335271
57SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16789199
58CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.16121181
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.16040966
60PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.15391435
61ERA_21632823_ChIP-Seq_H3396_Human1.14629247
62NANOG_20526341_ChIP-Seq_ESCs_Human1.12866821
63FOXA1_25329375_ChIP-Seq_VCAP_Human1.12518023
64FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12518023
65RNF2_18974828_ChIP-Seq_MESCs_Mouse1.12183143
66EZH2_18974828_ChIP-Seq_MESCs_Mouse1.12183143
67CREB1_15753290_ChIP-ChIP_HEK293T_Human1.11802996
68SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.11776958
69TP63_19390658_ChIP-ChIP_HaCaT_Human1.11548374
70JARID2_20075857_ChIP-Seq_MESCs_Mouse1.10414794
71SOX2_19829295_ChIP-Seq_ESCs_Human1.10227380
72NANOG_19829295_ChIP-Seq_ESCs_Human1.10227380
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.09409551
74PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09245703
75CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07415490
76KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05957717
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05406464
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03436934
79SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.02870188
80SMAD3_21741376_ChIP-Seq_EPCs_Human1.02379518
81YY1_21170310_ChIP-Seq_MESCs_Mouse1.01992748
82CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99636428
83EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.98665140
84E2F4_17652178_ChIP-ChIP_JURKAT_Human0.98088080
85MYC_19829295_ChIP-Seq_ESCs_Human0.97917558
86SMAD4_21741376_ChIP-Seq_EPCs_Human0.97539715
87RNF2_27304074_Chip-Seq_NSC_Mouse0.96532439
88P53_21459846_ChIP-Seq_SAOS-2_Human0.96187726
89ZFP57_27257070_Chip-Seq_ESCs_Mouse0.95981618
90KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.95757235
91SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.95571602
92FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.94554650
93PIAS1_25552417_ChIP-Seq_VCAP_Human0.94011812
94HOXB7_26014856_ChIP-Seq_BT474_Human0.94011224
95RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.92725547
96MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92660805
97IGF1R_20145208_ChIP-Seq_DFB_Human0.91267078
98CBP_20019798_ChIP-Seq_JUKART_Human0.91146127
99IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.91146127
100TAF2_19829295_ChIP-Seq_ESCs_Human0.90285208

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.99713191
2MP0010030_abnormal_orbit_morphology4.81193309
3MP0006292_abnormal_olfactory_placode4.07600604
4MP0000604_amyloidosis2.65643741
5MP0002102_abnormal_ear_morphology2.64650802
6MP0005377_hearing/vestibular/ear_phenot2.43594884
7MP0003878_abnormal_ear_physiology2.43594884
8MP0001293_anophthalmia2.28607293
9MP0008789_abnormal_olfactory_epithelium2.21976012
10MP0005408_hypopigmentation2.20739768
11MP0001485_abnormal_pinna_reflex2.17405279
12MP0001986_abnormal_taste_sensitivity2.15583698
13MP0002234_abnormal_pharynx_morphology2.14598153
14MP0002938_white_spotting2.08007011
15MP0004133_heterotaxia2.01896997
16MP0002638_abnormal_pupillary_reflex1.94579430
17MP0005394_taste/olfaction_phenotype1.92955490
18MP0005499_abnormal_olfactory_system1.92955490
19MP0000049_abnormal_middle_ear1.89587629
20MP0003122_maternal_imprinting1.84694124
21MP0008872_abnormal_physiological_respon1.77015323
22MP0008877_abnormal_DNA_methylation1.76913942
23MP0003136_yellow_coat_color1.76356489
24MP0005646_abnormal_pituitary_gland1.72404363
25MP0001346_abnormal_lacrimal_gland1.71775635
26MP0000026_abnormal_inner_ear1.66232275
27MP0001984_abnormal_olfaction1.65270937
28MP0004142_abnormal_muscle_tone1.63151711
29MP0003646_muscle_fatigue1.62694750
30MP0002736_abnormal_nociception_after1.60684407
31MP0004885_abnormal_endolymph1.60091041
32MP0005248_abnormal_Harderian_gland1.59962437
33MP0005551_abnormal_eye_electrophysiolog1.58210972
34MP0003123_paternal_imprinting1.53104726
35MP0002653_abnormal_ependyma_morphology1.50048326
36MP0004742_abnormal_vestibular_system1.44777378
37MP0000566_synostosis1.44221851
38MP0003937_abnormal_limbs/digits/tail_de1.42674796
39MP0003938_abnormal_ear_development1.37174753
40MP0005423_abnormal_somatic_nervous1.36805808
41MP0002138_abnormal_hepatobiliary_system1.36507144
42MP0001968_abnormal_touch/_nociception1.35833360
43MP0005084_abnormal_gallbladder_morpholo1.29750790
44MP0002272_abnormal_nervous_system1.29115833
45MP0003880_abnormal_central_pattern1.28916675
46MP0003693_abnormal_embryo_hatching1.28174621
47MP0003718_maternal_effect1.28011911
48MP0002095_abnormal_skin_pigmentation1.25100492
49MP0000778_abnormal_nervous_system1.25050470
50MP0003121_genomic_imprinting1.21921913
51MP0005195_abnormal_posterior_eye1.14419008
52MP0000631_abnormal_neuroendocrine_gland1.12663992
53MP0001286_abnormal_eye_development1.10882040
54MP0001963_abnormal_hearing_physiology1.10551176
55MP0001486_abnormal_startle_reflex1.09328355
56MP0003011_delayed_dark_adaptation1.08596076
57MP0009384_cardiac_valve_regurgitation1.07382957
58MP0003119_abnormal_digestive_system1.03557109
59MP0003786_premature_aging1.02316591
60MP0002752_abnormal_somatic_nervous1.01975884
61MP0003936_abnormal_reproductive_system0.99616315
62MP0001348_abnormal_lacrimal_gland0.99003960
63MP0003879_abnormal_hair_cell0.98824944
64MP0003329_amyloid_beta_deposits0.98737400
65MP0005391_vision/eye_phenotype0.98496400
66MP0002233_abnormal_nose_morphology0.97862890
67MP0002184_abnormal_innervation0.95532340
68MP0004145_abnormal_muscle_electrophysio0.93646257
69MP0002697_abnormal_eye_size0.92378183
70MP0008875_abnormal_xenobiotic_pharmacok0.91008095
71MP0003567_abnormal_fetal_cardiomyocyte0.90636046
72MP0002210_abnormal_sex_determination0.89859475
73MP0006276_abnormal_autonomic_nervous0.89558144
74MP0003283_abnormal_digestive_organ0.85685772
75MP0001440_abnormal_grooming_behavior0.84617573
76MP0002092_abnormal_eye_morphology0.82911504
77MP0002557_abnormal_social/conspecific_i0.82837362
78MP0001529_abnormal_vocalization0.78740146
79MP0005253_abnormal_eye_physiology0.77744711
80MP0002277_abnormal_respiratory_mucosa0.77204736
81MP0001119_abnormal_female_reproductive0.76774073
82MP0006072_abnormal_retinal_apoptosis0.75528959
83MP0009745_abnormal_behavioral_response0.74734317
84MP0001324_abnormal_eye_pigmentation0.73738748
85MP0002249_abnormal_larynx_morphology0.73544462
86MP0000428_abnormal_craniofacial_morphol0.72261564
87MP0000372_irregular_coat_pigmentation0.70923809
88MP0001502_abnormal_circadian_rhythm0.70240437
89MP0002282_abnormal_trachea_morphology0.68135662
90MP0002735_abnormal_chemical_nociception0.68003324
91MP0009053_abnormal_anal_canal0.67380560
92MP0010329_abnormal_lipoprotein_level0.66486265
93MP0003755_abnormal_palate_morphology0.66079080
94MP0002116_abnormal_craniofacial_bone0.65747656
95MP0010094_abnormal_chromosome_stability0.65576157
96MP0001299_abnormal_eye_distance/0.65138485
97MP0002111_abnormal_tail_morphology0.62925367
98MP0002876_abnormal_thyroid_physiology0.62419873
99MP0003861_abnormal_nervous_system0.62117155
100MP0002928_abnormal_bile_duct0.60261924

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the sacrum (HP:0008517)5.84607571
2Reticulocytopenia (HP:0001896)4.93276794
3Type II lissencephaly (HP:0007260)3.46711306
4Abnormality of cells of the erythroid lineage (HP:0012130)3.25139787
5Maternal diabetes (HP:0009800)3.24282073
6Abnormality of midbrain morphology (HP:0002418)3.23804895
7Molar tooth sign on MRI (HP:0002419)3.23804895
8Cerebellar dysplasia (HP:0007033)2.97360864
9Abnormality of the labia minora (HP:0012880)2.91975622
10Myelomeningocele (HP:0002475)2.91497942
11Bile duct proliferation (HP:0001408)2.81873540
12Abnormal biliary tract physiology (HP:0012439)2.81873540
13Abnormality of the pons (HP:0007361)2.81191015
14Meningocele (HP:0002435)2.78454514
15Anencephaly (HP:0002323)2.76565290
16Pancreatic cysts (HP:0001737)2.74390761
17Pancreatic fibrosis (HP:0100732)2.72891690
18Septo-optic dysplasia (HP:0100842)2.72321055
19Partial duplication of thumb phalanx (HP:0009944)2.62419254
20Macrocytic anemia (HP:0001972)2.62102876
21Bifid tongue (HP:0010297)2.61629191
22Acute necrotizing encephalopathy (HP:0006965)2.61539205
23Hypoplasia of the pons (HP:0012110)2.59831360
24Anophthalmia (HP:0000528)2.57274728
25True hermaphroditism (HP:0010459)2.45822866
26Nephronophthisis (HP:0000090)2.45698193
27Chronic hepatic failure (HP:0100626)2.43856441
28Absent rod-and cone-mediated responses on ERG (HP:0007688)2.41457718
29Morphological abnormality of the middle ear (HP:0008609)2.39669613
30Ectopic kidney (HP:0000086)2.36494030
31Absent thumb (HP:0009777)2.33106228
32Hepatoblastoma (HP:0002884)2.31713028
33Acute encephalopathy (HP:0006846)2.30402189
34Hyperglycinemia (HP:0002154)2.29774449
35Pendular nystagmus (HP:0012043)2.28877927
36Abnormality of the phalanges of the 5th finger (HP:0004213)2.27472714
37Abnormality of the middle phalanges of the toes (HP:0010183)2.26071414
38Abnormality of alanine metabolism (HP:0010916)2.25402169
39Hyperalaninemia (HP:0003348)2.25402169
40Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.25402169
41Oligodactyly (hands) (HP:0001180)2.24772111
42Rib fusion (HP:0000902)2.23150616
43Abnormal mitochondria in muscle tissue (HP:0008316)2.21020326
44Hypoplasia of the radius (HP:0002984)2.20344301
45Aplasia/Hypoplasia of the sternum (HP:0006714)2.20174261
46Abnormal number of erythroid precursors (HP:0012131)2.19004744
47Abnormality of the renal medulla (HP:0100957)2.18842899
48Stenosis of the external auditory canal (HP:0000402)2.17300768
49Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.16863791
50Abnormal ciliary motility (HP:0012262)2.16390691
51Horseshoe kidney (HP:0000085)2.14869535
52Aplasia/Hypoplasia of the spleen (HP:0010451)2.14269094
53Asplenia (HP:0001746)2.13817447
54Supernumerary spleens (HP:0009799)2.13441762
55Drooling (HP:0002307)2.11593430
56Abnormal rod and cone electroretinograms (HP:0008323)2.11308393
57Chorioretinal atrophy (HP:0000533)2.10019456
58Triphalangeal thumb (HP:0001199)2.09977403
59Failure to thrive in infancy (HP:0001531)2.09659899
60Stomatitis (HP:0010280)2.08790347
61Partial duplication of the phalanx of hand (HP:0009999)2.07225782
62Absent septum pellucidum (HP:0001331)2.06450739
63Osteomalacia (HP:0002749)2.05562841
64Aplasia/Hypoplasia of the uvula (HP:0010293)2.01817983
65High anterior hairline (HP:0009890)1.98895365
66Depressed nasal ridge (HP:0000457)1.98208325
67Cystic liver disease (HP:0006706)1.97352214
68Progressive macrocephaly (HP:0004481)1.96832052
69Anterior segment dysgenesis (HP:0007700)1.96426054
70Cutaneous finger syndactyly (HP:0010554)1.96065717
71Dyschromatopsia (HP:0007641)1.95285812
72Intestinal atresia (HP:0011100)1.94702247
73Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.94141653
74Severe muscular hypotonia (HP:0006829)1.92877047
75Abnormality of incisor morphology (HP:0011063)1.92688532
76Excessive salivation (HP:0003781)1.92064324
77Holoprosencephaly (HP:0001360)1.91615490
78Cutaneous syndactyly (HP:0012725)1.91218994
79Pallor (HP:0000980)1.89788025
80Medial flaring of the eyebrow (HP:0010747)1.89274570
81Dandy-Walker malformation (HP:0001305)1.86388203
82Oligodactyly (HP:0012165)1.86188143
83Meckel diverticulum (HP:0002245)1.85736595
84Thyroid-stimulating hormone excess (HP:0002925)1.85729628
85Optic disc pallor (HP:0000543)1.85273664
86Enlarged kidneys (HP:0000105)1.84197913
87Abnormality of the phalanges of the 2nd finger (HP:0009541)1.83895181
88Hypoplasia of the ulna (HP:0003022)1.83517214
89Sclerocornea (HP:0000647)1.81643883
90Bilateral microphthalmos (HP:0007633)1.78585429
91Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.78573739
92Labial hypoplasia (HP:0000066)1.77612338
93Vitreoretinal degeneration (HP:0000655)1.77341034
94Forearm undergrowth (HP:0009821)1.77040228
95Hypoplastic female external genitalia (HP:0012815)1.75418084
96Lissencephaly (HP:0001339)1.75076771
97Narrow forehead (HP:0000341)1.74261769
98Congenital stationary night blindness (HP:0007642)1.73621950
99Abnormality of the ileum (HP:0001549)1.72883299
100Vaginal atresia (HP:0000148)1.72276733

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK43.14439025
2TRIM282.82773248
3CDC72.64005826
4MAP3K42.58951369
5PLK42.56323723
6PDK22.52254433
7ADRBK22.46768710
8TNIK2.45192494
9STK392.35444641
10OBSCN2.19395315
11WNK32.02677219
12MAP4K22.00282496
13EPHB21.99283655
14CASK1.96170269
15GRK11.85192331
16DYRK21.84795343
17PIK3CA1.80966536
18ZAK1.70273283
19PLK21.69409509
20FRK1.63219917
21TLK11.57671878
22NME11.52664021
23LRRK21.50111140
24CAMK11.49288116
25OXSR11.44332975
26WNK11.39864648
27TAF11.38733229
28TXK1.36168989
29TIE11.32564808
30INSRR1.30279108
31BCKDK1.29797854
32EPHA31.26759357
33NUAK11.19193712
34PRKCH1.17761559
35PRKCG1.17667681
36PINK11.14313020
37DAPK31.11865112
38FGFR21.09900998
39PAK31.09882693
40MAP3K121.06585714
41DAPK21.06542018
42MAP2K41.00124856
43ADRBK10.94035790
44PNCK0.90816163
45CAMK40.88769766
46VRK20.88456549
47TGFBR10.86913553
48STK160.85103792
49ATR0.83371510
50PASK0.76920393
51AURKB0.76806323
52STK110.76193241
53BUB10.72148635
54CSNK2A20.71823287
55MAPKAPK50.70841708
56PRKCQ0.69506418
57FGFR10.68967968
58PRKCI0.67575313
59WEE10.64682924
60CAMK1G0.64379394
61CDK190.63433376
62PHKG10.63305282
63PHKG20.63305282
64AURKA0.63280035
65MARK30.61965357
66NME20.61682071
67VRK10.61192957
68MAP2K70.61024673
69CAMK1D0.60611521
70BMPR1B0.60533437
71CAMK2A0.60518907
72PRKACA0.60312731
73PRKCE0.58611197
74SRPK10.55180073
75PIK3CG0.54948918
76MARK10.53348794
77PRKCA0.52812829
78MAPK130.50819863
79CDK80.50107605
80PLK30.49571444
81STK30.49326044
82PLK10.49204218
83RPS6KA60.48944746
84ATM0.48305978
85NTRK20.47932519
86CAMK2D0.47140363
87CSNK2A10.46332904
88CSNK1G20.45299566
89CAMKK20.45045295
90MKNK10.44622239
91TEC0.44003907
92PRKDC0.43365247
93CSNK1E0.43062090
94CAMK2B0.42977137
95PIM10.41809440
96MAP2K60.41034153
97DAPK10.40452653
98MAPKAPK30.36790610
99ERBB40.36523715
100CSNK1G10.35322340

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.63132205
2Protein export_Homo sapiens_hsa030603.91035016
3Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.09138878
4Oxidative phosphorylation_Homo sapiens_hsa001902.63437972
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.55494788
6Homologous recombination_Homo sapiens_hsa034402.36131247
7Fanconi anemia pathway_Homo sapiens_hsa034602.33592702
8Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.15615357
9RNA polymerase_Homo sapiens_hsa030202.06253927
10Parkinsons disease_Homo sapiens_hsa050122.03422943
11Cardiac muscle contraction_Homo sapiens_hsa042602.00890850
12Mismatch repair_Homo sapiens_hsa034301.83180655
13Linoleic acid metabolism_Homo sapiens_hsa005911.80474635
14Caffeine metabolism_Homo sapiens_hsa002321.77789724
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.74317478
16Basal transcription factors_Homo sapiens_hsa030221.73169251
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.66438897
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.64019306
19Proteasome_Homo sapiens_hsa030501.61637097
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.61319108
21Huntingtons disease_Homo sapiens_hsa050161.56810004
22RNA degradation_Homo sapiens_hsa030181.55563515
23Arginine and proline metabolism_Homo sapiens_hsa003301.54250761
24Steroid biosynthesis_Homo sapiens_hsa001001.51509082
25Phototransduction_Homo sapiens_hsa047441.47764154
26Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.40755569
27Propanoate metabolism_Homo sapiens_hsa006401.37484632
28Alzheimers disease_Homo sapiens_hsa050101.36070695
29Nucleotide excision repair_Homo sapiens_hsa034201.33999794
30Nicotine addiction_Homo sapiens_hsa050331.30810260
31Asthma_Homo sapiens_hsa053101.30272037
32Hedgehog signaling pathway_Homo sapiens_hsa043401.27719009
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.25955729
34Basal cell carcinoma_Homo sapiens_hsa052171.24616528
35Peroxisome_Homo sapiens_hsa041461.23144520
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.16665982
37Tryptophan metabolism_Homo sapiens_hsa003801.16384836
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13936922
39DNA replication_Homo sapiens_hsa030301.13163018
40Pyrimidine metabolism_Homo sapiens_hsa002401.09699940
41Regulation of autophagy_Homo sapiens_hsa041401.09140897
42Butanoate metabolism_Homo sapiens_hsa006501.08705984
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08675721
44Thyroid hormone synthesis_Homo sapiens_hsa049181.07304699
45One carbon pool by folate_Homo sapiens_hsa006701.06874571
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.05360503
47Fat digestion and absorption_Homo sapiens_hsa049751.02533989
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.01278989
49Fatty acid degradation_Homo sapiens_hsa000710.92264592
50Vitamin digestion and absorption_Homo sapiens_hsa049770.90358444
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88733444
52Ether lipid metabolism_Homo sapiens_hsa005650.86320140
53Base excision repair_Homo sapiens_hsa034100.82668830
54Morphine addiction_Homo sapiens_hsa050320.77485521
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76940971
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.76415983
57Primary bile acid biosynthesis_Homo sapiens_hsa001200.75403619
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.75148989
59Retinol metabolism_Homo sapiens_hsa008300.72855229
60Purine metabolism_Homo sapiens_hsa002300.71821594
61Ovarian steroidogenesis_Homo sapiens_hsa049130.67025519
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66968626
63Olfactory transduction_Homo sapiens_hsa047400.63802342
64Insulin secretion_Homo sapiens_hsa049110.63159356
65Metabolic pathways_Homo sapiens_hsa011000.61517100
66Folate biosynthesis_Homo sapiens_hsa007900.60026007
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.59479260
68Intestinal immune network for IgA production_Homo sapiens_hsa046720.58692050
69Arachidonic acid metabolism_Homo sapiens_hsa005900.58680351
70Nitrogen metabolism_Homo sapiens_hsa009100.57374182
71Chemical carcinogenesis_Homo sapiens_hsa052040.55108944
72Wnt signaling pathway_Homo sapiens_hsa043100.47334249
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47011650
74RNA transport_Homo sapiens_hsa030130.42279021
75Autoimmune thyroid disease_Homo sapiens_hsa053200.41566793
76Allograft rejection_Homo sapiens_hsa053300.41153165
77Hippo signaling pathway_Homo sapiens_hsa043900.41111918
78Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.38862564
79PPAR signaling pathway_Homo sapiens_hsa033200.38795499
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.37981619
81Type I diabetes mellitus_Homo sapiens_hsa049400.37238598
82Primary immunodeficiency_Homo sapiens_hsa053400.36623553
83Glutamatergic synapse_Homo sapiens_hsa047240.35861118
84Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.34710654
85GABAergic synapse_Homo sapiens_hsa047270.33062951
86Fatty acid biosynthesis_Homo sapiens_hsa000610.33007069
87Salivary secretion_Homo sapiens_hsa049700.32115653
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.31961492
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31221966
90Pyruvate metabolism_Homo sapiens_hsa006200.30166643
91Taste transduction_Homo sapiens_hsa047420.30005110
92Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28939036
93Glycerolipid metabolism_Homo sapiens_hsa005610.28285884
94Sulfur relay system_Homo sapiens_hsa041220.28203936
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28052984
96Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27059263
97Cysteine and methionine metabolism_Homo sapiens_hsa002700.26938704
98Galactose metabolism_Homo sapiens_hsa000520.25970277
99Hematopoietic cell lineage_Homo sapiens_hsa046400.25850818
100Melanogenesis_Homo sapiens_hsa049160.25799353

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