RPL7P30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.58916794
2proteasome assembly (GO:0043248)5.53511640
3negative regulation of execution phase of apoptosis (GO:1900118)4.92085529
4cell wall macromolecule metabolic process (GO:0044036)4.66894092
5glucosamine-containing compound catabolic process (GO:1901072)4.50069090
6regulation of memory T cell differentiation (GO:0043380)4.31970484
7T cell migration (GO:0072678)4.24882183
8positive regulation of interleukin-17 production (GO:0032740)4.09041564
9positive regulation of defense response to virus by host (GO:0002230)4.09030230
10positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.93986906
11grooming behavior (GO:0007625)3.93344413
12detection of chemical stimulus involved in sensory perception of smell (GO:0050911)3.86334186
13regulation of defense response to virus by host (GO:0050691)3.77620877
14positive regulation of T-helper 1 type immune response (GO:0002827)3.77366292
15interferon-gamma production (GO:0032609)3.75739565
16response to interferon-beta (GO:0035456)3.67212512
17immunoglobulin mediated immune response (GO:0016064)3.62585126
18rRNA methylation (GO:0031167)3.58076660
19negative regulation of B cell apoptotic process (GO:0002903)3.52077279
20rRNA modification (GO:0000154)3.48217714
21positive regulation of prostaglandin secretion (GO:0032308)3.47353810
22cellular response to exogenous dsRNA (GO:0071360)3.45447352
23regulation of mitotic spindle checkpoint (GO:1903504)3.39294196
24regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.39294196
25cellular response to dsRNA (GO:0071359)3.35707418
26positive regulation of alpha-beta T cell proliferation (GO:0046641)3.32216168
27positive regulation of T cell cytokine production (GO:0002726)3.31767294
28sensory perception of smell (GO:0007608)3.26159305
29protein polyglutamylation (GO:0018095)3.25899401
30regulation of activation of Janus kinase activity (GO:0010533)3.16842013
31positive regulation of tolerance induction (GO:0002645)3.15567985
32positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)3.14418064
33behavioral response to nicotine (GO:0035095)3.14001518
34regulation of penile erection (GO:0060405)3.12529366
35regulation of interleukin-2 biosynthetic process (GO:0045076)3.09293766
36lymphocyte chemotaxis (GO:0048247)3.07444460
37ribosomal small subunit assembly (GO:0000028)3.07157623
38mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.06739783
39positive regulation of mitochondrial fission (GO:0090141)3.05236059
40protein deneddylation (GO:0000338)3.00975962
41chaperone mediated protein folding requiring cofactor (GO:0051085)2.99936922
42RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.99652951
43tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.99652951
44positive regulation of interleukin-2 production (GO:0032743)2.99432111
45positive regulation of gamma-delta T cell activation (GO:0046645)2.98673152
46endoderm formation (GO:0001706)2.97517053
47behavioral response to ethanol (GO:0048149)2.97473809
48negative regulation of lymphocyte apoptotic process (GO:0070229)2.96816899
49negative regulation of interleukin-1 beta production (GO:0032691)2.96749091
50positive regulation of cAMP-mediated signaling (GO:0043950)2.96095687
51negative T cell selection (GO:0043383)2.94805673
52B cell mediated immunity (GO:0019724)2.94018851
53T cell receptor signaling pathway (GO:0050852)2.93431288
54regulation of T-helper 1 type immune response (GO:0002825)2.90290835
55regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.86802566
56protein complex biogenesis (GO:0070271)2.84570081
57negative regulation of T cell apoptotic process (GO:0070233)2.84216280
58regulation of alpha-beta T cell proliferation (GO:0046640)2.81113947
59negative regulation of mast cell activation (GO:0033004)2.80989385
60positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.79464416
61regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.79286035
62cellular ketone body metabolic process (GO:0046950)2.76836680
63positive regulation of T cell mediated cytotoxicity (GO:0001916)2.75837437
64cytidine metabolic process (GO:0046087)2.74811409
65cytidine catabolic process (GO:0006216)2.74811409
66cytidine deamination (GO:0009972)2.74811409
67regulation of T cell tolerance induction (GO:0002664)2.74743145
68mannosylation (GO:0097502)2.74635705
69single strand break repair (GO:0000012)2.72999819
70regulation of isotype switching to IgG isotypes (GO:0048302)2.72954282
71mast cell activation involved in immune response (GO:0002279)2.72893714
72mast cell degranulation (GO:0043303)2.72893714
73exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.71771994
74detection of chemical stimulus involved in sensory perception (GO:0050907)2.70393647
75positive regulation of interleukin-4 production (GO:0032753)2.70344681
76negative regulation of interleukin-1 production (GO:0032692)2.69614049
77ATP synthesis coupled proton transport (GO:0015986)2.69593733
78energy coupled proton transport, down electrochemical gradient (GO:0015985)2.69593733
79regulation of T cell cytokine production (GO:0002724)2.67861884
80regulation of prostaglandin secretion (GO:0032306)2.67768780
81regulation of immunoglobulin secretion (GO:0051023)2.65195264
82mitochondrial respiratory chain complex assembly (GO:0033108)2.65001949
83positive regulation of protein homooligomerization (GO:0032464)2.64727131
84thymic T cell selection (GO:0045061)2.62962105
85chaperone-mediated protein transport (GO:0072321)2.62826438
86regulation of tolerance induction (GO:0002643)2.62355804
87regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.62265995
88centriole replication (GO:0007099)2.61342849
89response to dsRNA (GO:0043331)2.61225548
90mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.60269255
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.60052204
92positive regulation of B cell differentiation (GO:0045579)2.59346859
93positive thymic T cell selection (GO:0045059)2.59276189
94regulation of B cell differentiation (GO:0045577)2.55915628
95RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.55294576
96positive T cell selection (GO:0043368)2.53619795
97regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.53480106
98negative thymic T cell selection (GO:0045060)2.52525207
99signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.52144302
100signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.52144302

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat6.59608534
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.31186650
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.86626687
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.62387561
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.11314584
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.87696321
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.85273915
8ELF1_17652178_ChIP-ChIP_JURKAT_Human2.81007883
9IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.66227469
10NOTCH1_21737748_ChIP-Seq_TLL_Human2.65469048
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50222904
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.49985999
13HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.48056072
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.39769461
15VDR_23849224_ChIP-Seq_CD4+_Human2.36058955
16ESR1_15608294_ChIP-ChIP_MCF-7_Human2.29809397
17IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.29395236
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.29016663
19ELK1_19687146_ChIP-ChIP_HELA_Human2.26737989
20SRF_21415370_ChIP-Seq_HL-1_Mouse2.14452046
21VDR_22108803_ChIP-Seq_LS180_Human2.13621053
22CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.11435208
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.97849954
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.93142209
25MYC_18940864_ChIP-ChIP_HL60_Human1.92419691
26FOXP3_21729870_ChIP-Seq_TREG_Human1.90834899
27SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.88815015
28PADI4_21655091_ChIP-ChIP_MCF-7_Human1.81230482
29EGR1_23403033_ChIP-Seq_LIVER_Mouse1.75172105
30E2F4_17652178_ChIP-ChIP_JURKAT_Human1.74181345
31FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.70990349
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70326515
33SCL_19346495_ChIP-Seq_HPC-7_Human1.64677638
34STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.63730808
35LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.62807049
36GATA3_26560356_Chip-Seq_TH2_Human1.57394497
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.57200901
38MYB_26560356_Chip-Seq_TH2_Human1.57104534
39CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.54465549
40DCP1A_22483619_ChIP-Seq_HELA_Human1.51054965
41SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48214034
42MYC_18358816_ChIP-ChIP_MESCs_Mouse1.47848701
43BP1_19119308_ChIP-ChIP_Hs578T_Human1.47778758
44SPI1_23547873_ChIP-Seq_NB4_Human1.41675216
45CIITA_25753668_ChIP-Seq_RAJI_Human1.40404701
46STAT4_19710469_ChIP-ChIP_TH1__Mouse1.39499682
47E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39136288
48MYC_18555785_ChIP-Seq_MESCs_Mouse1.38274066
49ZNF274_21170338_ChIP-Seq_K562_Hela1.36298632
50PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.35212719
51HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34496198
52ELK1_22589737_ChIP-Seq_MCF10A_Human1.33434085
53FLI1_27457419_Chip-Seq_LIVER_Mouse1.32473225
54GATA3_21878914_ChIP-Seq_MCF-7_Human1.32379962
55PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32181608
56MYC_19030024_ChIP-ChIP_MESCs_Mouse1.31418069
57EWS_26573619_Chip-Seq_HEK293_Human1.27890272
58AR_20517297_ChIP-Seq_VCAP_Human1.26018305
59RUNX_20019798_ChIP-Seq_JUKART_Human1.22980143
60TP53_22573176_ChIP-Seq_HFKS_Human1.22659476
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.22380123
62YY1_22570637_ChIP-Seq_MALME-3M_Human1.20947321
63BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20070439
64GATA3_27048872_Chip-Seq_THYMUS_Human1.18731606
65FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.18716770
66RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.17542728
67EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15818288
68FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.15609104
69IRF8_21731497_ChIP-ChIP_J774_Mouse1.14302537
70MYB_26560356_Chip-Seq_TH1_Human1.12900663
71TAF2_19829295_ChIP-Seq_ESCs_Human1.12740818
72FOXA1_25329375_ChIP-Seq_VCAP_Human1.09924984
73FOXA1_27270436_Chip-Seq_PROSTATE_Human1.09924984
74CTCF_20526341_ChIP-Seq_ESCs_Human1.09768183
75RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09271402
76PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.09146449
77ERG_20517297_ChIP-Seq_VCAP_Human1.08571780
78FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07558249
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07466348
80STAT1_20625510_ChIP-Seq_HELA_Human1.05725463
81MYC_19079543_ChIP-ChIP_MESCs_Mouse1.03862809
82GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.03711536
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.03170324
84TTF2_22483619_ChIP-Seq_HELA_Human1.01763804
85HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.00613759
86FOXH1_21741376_ChIP-Seq_EPCs_Human1.00300868
87RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98530061
88XRN2_22483619_ChIP-Seq_HELA_Human0.98456764
89ER_23166858_ChIP-Seq_MCF-7_Human0.97980258
90BCL6_27268052_Chip-Seq_Bcells_Human0.97440778
91EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.97227231
92BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96892735
93ERA_21632823_ChIP-Seq_H3396_Human0.96634398
94MAF_26560356_Chip-Seq_TH1_Human0.96597954
95PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.94779778
96NANOG_20526341_ChIP-Seq_ESCs_Human0.93794581
97MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.93645746
98HOXB7_26014856_ChIP-Seq_BT474_Human0.92926783
99E2F1_18555785_ChIP-Seq_MESCs_Mouse0.91899931
100IGF1R_20145208_ChIP-Seq_DFB_Human0.90912289

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.30727108
2MP0008877_abnormal_DNA_methylation3.58509787
3MP0001986_abnormal_taste_sensitivity3.54303949
4MP0002102_abnormal_ear_morphology3.45487649
5MP0005646_abnormal_pituitary_gland2.87189807
6MP0009785_altered_susceptibility_to2.82599760
7MP0003786_premature_aging2.76302833
8MP0003045_fibrosis2.59906628
9MP0004147_increased_porphyrin_level2.58133451
10MP0001835_abnormal_antigen_presentation2.55640632
11MP0000685_abnormal_immune_system2.55425630
12MP0006036_abnormal_mitochondrial_physio2.50872717
13MP0008872_abnormal_physiological_respon2.13835026
14MP0008995_early_reproductive_senescence1.97459770
15MP0008058_abnormal_DNA_repair1.96080823
16MP0005423_abnormal_somatic_nervous1.94323554
17MP0004885_abnormal_endolymph1.91615541
18MP0008875_abnormal_xenobiotic_pharmacok1.91028557
19MP0001800_abnormal_humoral_immune1.85391478
20MP0005000_abnormal_immune_tolerance1.83661105
21MP0002006_tumorigenesis1.81765815
22MP0003866_abnormal_defecation1.76168967
23MP0002723_abnormal_immune_serum1.76103916
24MP0001661_extended_life_span1.75722058
25MP0006072_abnormal_retinal_apoptosis1.74785020
26MP0002166_altered_tumor_susceptibility1.72801457
27MP0004145_abnormal_muscle_electrophysio1.71043804
28MP0005025_abnormal_response_to1.70021749
29MP0001790_abnormal_immune_system1.60522577
30MP0005387_immune_system_phenotype1.60522577
31MP0001905_abnormal_dopamine_level1.59636162
32MP0002452_abnormal_antigen_presenting1.58842493
33MP0003436_decreased_susceptibility_to1.55608034
34MP0002148_abnormal_hypersensitivity_rea1.49623503
35MP0003950_abnormal_plasma_membrane1.48632587
36MP0002420_abnormal_adaptive_immunity1.47399976
37MP0003763_abnormal_thymus_physiology1.46837496
38MP0001819_abnormal_immune_cell1.46267769
39MP0003878_abnormal_ear_physiology1.44750371
40MP0005377_hearing/vestibular/ear_phenot1.44750371
41MP0002396_abnormal_hematopoietic_system1.43011522
42MP0002132_abnormal_respiratory_system1.40053949
43MP0006035_abnormal_mitochondrial_morpho1.34953557
44MP0003646_muscle_fatigue1.32792345
45MP0005332_abnormal_amino_acid1.30717491
46MP0009764_decreased_sensitivity_to1.27927621
47MP0002398_abnormal_bone_marrow1.26937311
48MP0005551_abnormal_eye_electrophysiolog1.25410139
49MP0005166_decreased_susceptibility_to1.24888219
50MP0005360_urolithiasis1.24145156
51MP0001873_stomach_inflammation1.23740580
52MP0002405_respiratory_system_inflammati1.20729617
53MP0005645_abnormal_hypothalamus_physiol1.19689475
54MP0005670_abnormal_white_adipose1.17510903
55MP0001529_abnormal_vocalization1.17427601
56MP0003724_increased_susceptibility_to1.16935280
57MP0002419_abnormal_innate_immunity1.13702668
58MP0004134_abnormal_chest_morphology1.13600673
59MP0000716_abnormal_immune_system1.12357785
60MP0001440_abnormal_grooming_behavior1.09469460
61MP0000689_abnormal_spleen_morphology1.07770201
62MP0006276_abnormal_autonomic_nervous1.06755453
63MP0005083_abnormal_biliary_tract1.06374255
64MP0009333_abnormal_splenocyte_physiolog1.03371627
65MP0004782_abnormal_surfactant_physiolog1.02318515
66MP0010155_abnormal_intestine_physiology1.01804355
67MP0003195_calcinosis1.00931432
68MP0008469_abnormal_protein_level1.00235110
69MP0002722_abnormal_immune_system0.99841232
70MP0001919_abnormal_reproductive_system0.99465752
71MP0003111_abnormal_nucleus_morphology0.94728775
72MP0002009_preneoplasia0.94650931
73MP0003011_delayed_dark_adaptation0.94643959
74MP0002429_abnormal_blood_cell0.94080117
75MP0002019_abnormal_tumor_incidence0.93808082
76MP0008007_abnormal_cellular_replicative0.92724385
77MP0004019_abnormal_vitamin_homeostasis0.91265697
78MP0005075_abnormal_melanosome_morpholog0.89904329
79MP0000703_abnormal_thymus_morphology0.89444217
80MP0002837_dystrophic_cardiac_calcinosis0.89093371
81MP0010094_abnormal_chromosome_stability0.87729257
82MP0009697_abnormal_copulation0.87045745
83MP0001845_abnormal_inflammatory_respons0.86529626
84MP0004142_abnormal_muscle_tone0.86359632
85MP0004947_skin_inflammation0.85053743
86MP0005085_abnormal_gallbladder_physiolo0.83225042
87MP0005389_reproductive_system_phenotype0.82146348
88MP0003693_abnormal_embryo_hatching0.82131616
89MP0005408_hypopigmentation0.82080087
90MP0008057_abnormal_DNA_replication0.81765253
91MP0005410_abnormal_fertilization0.80504470
92MP0001881_abnormal_mammary_gland0.80119700
93MP0003718_maternal_effect0.79759789
94MP0003300_gastrointestinal_ulcer0.78885952
95MP0002653_abnormal_ependyma_morphology0.75516934
96MP0001853_heart_inflammation0.75413129
97MP0001764_abnormal_homeostasis0.74423090
98MP0001545_abnormal_hematopoietic_system0.71819541
99MP0005397_hematopoietic_system_phenotyp0.71819541
100MP0001501_abnormal_sleep_pattern0.70902367

Predicted human phenotypes

RankGene SetZ-score
1Stomatitis (HP:0010280)6.25851535
2Elevated erythrocyte sedimentation rate (HP:0003565)4.13873994
3Aplastic anemia (HP:0001915)4.03257425
4IgG deficiency (HP:0004315)3.91660546
5Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.88229582
6Decreased activity of mitochondrial respiratory chain (HP:0008972)3.88229582
7Increased IgM level (HP:0003496)3.75342428
8Abnormal mitochondria in muscle tissue (HP:0008316)3.73238319
9Renal Fanconi syndrome (HP:0001994)3.70742969
10Abnormal drinking behavior (HP:0030082)3.55496195
11Polydipsia (HP:0001959)3.55496195
12Entropion (HP:0000621)3.40508216
13Increased intramyocellular lipid droplets (HP:0012240)3.32329068
14Abnormality of DNA repair (HP:0003254)3.30934651
15Acute necrotizing encephalopathy (HP:0006965)3.29976208
16Mitochondrial inheritance (HP:0001427)3.10893420
17Ragged-red muscle fibers (HP:0003200)3.10037099
18Hypoproteinemia (HP:0003075)3.09398834
19Generalized aminoaciduria (HP:0002909)3.03568415
20Progressive macrocephaly (HP:0004481)2.97954311
21Acute encephalopathy (HP:0006846)2.86294185
22Increased CSF lactate (HP:0002490)2.78374057
23Increased muscle lipid content (HP:0009058)2.73711568
24Abnormality of T cell physiology (HP:0011840)2.73150889
25Stomach cancer (HP:0012126)2.71647722
26Increased hepatocellular lipid droplets (HP:0006565)2.71027384
27Hepatocellular necrosis (HP:0001404)2.68290724
28Abnormality of the prostate (HP:0008775)2.67422685
29Molar tooth sign on MRI (HP:0002419)2.66143337
30Abnormality of midbrain morphology (HP:0002418)2.66143337
31Prostate neoplasm (HP:0100787)2.64750979
32Abnormality of T cells (HP:0002843)2.63640202
33Increased serum lactate (HP:0002151)2.61753527
34Type I diabetes mellitus (HP:0100651)2.61436256
35Polyuria (HP:0000103)2.59554863
36Hepatic necrosis (HP:0002605)2.58307746
37Poikiloderma (HP:0001029)2.51116079
38Panhypogammaglobulinemia (HP:0003139)2.50046323
39Lipid accumulation in hepatocytes (HP:0006561)2.45925597
40Tubular atrophy (HP:0000092)2.41433100
41Autoimmune hemolytic anemia (HP:0001890)2.41010872
42Exertional dyspnea (HP:0002875)2.40949656
43Neonatal respiratory distress (HP:0002643)2.40115000
44Pancreatic cysts (HP:0001737)2.37419973
45Glycosuria (HP:0003076)2.35717983
46Abnormality of urine glucose concentration (HP:0011016)2.35717983
47Alveolar cell carcinoma (HP:0006519)2.35253108
48Absent thumb (HP:0009777)2.34014784
49Abnormality of the costochondral junction (HP:0000919)2.31464051
50Chromsome breakage (HP:0040012)2.27900691
51Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.27852557
52Abnormality of renal resorption (HP:0011038)2.27615729
53T lymphocytopenia (HP:0005403)2.26790985
54Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.26204480
55IgM deficiency (HP:0002850)2.24561678
56Absent rod-and cone-mediated responses on ERG (HP:0007688)2.23999700
57Myositis (HP:0100614)2.23422637
58Pancytopenia (HP:0001876)2.23344592
59Hypoplastic pelvis (HP:0008839)2.21135911
60Anhidrosis (HP:0000970)2.19868664
61Abnormality of T cell number (HP:0011839)2.19820666
62Lactic acidosis (HP:0003128)2.19171570
63Abnormal delayed hypersensitivity skin test (HP:0002963)2.17081722
64Severe combined immunodeficiency (HP:0004430)2.14374454
65Mesangial abnormality (HP:0001966)2.13637124
66Abnormal number of erythroid precursors (HP:0012131)2.12961573
67Abnormality of macular pigmentation (HP:0008002)2.11396262
68Hypoplasia of the uterus (HP:0000013)2.11333527
69Recurrent corneal erosions (HP:0000495)2.09741175
70Decreased electroretinogram (ERG) amplitude (HP:0000654)2.09494660
71Abnormal urine output (HP:0012590)2.08136426
72Hypophosphatemic rickets (HP:0004912)2.08062268
73Cerebral edema (HP:0002181)2.06752357
74Abnormal rod and cone electroretinograms (HP:0008323)2.05168105
75Meckel diverticulum (HP:0002245)2.03759795
76Type I transferrin isoform profile (HP:0003642)2.02548644
77Facial diplegia (HP:0001349)2.00567452
78Aplasia/Hypoplasia of the uvula (HP:0010293)1.99767697
79Spastic paraparesis (HP:0002313)1.98934611
80Type II lissencephaly (HP:0007260)1.97261932
81Abnormality of the ileum (HP:0001549)1.96729060
82Clubbing of toes (HP:0100760)1.96583518
83Combined immunodeficiency (HP:0005387)1.95296205
84Pustule (HP:0200039)1.91475045
85Abnormality of sulfur amino acid metabolism (HP:0004339)1.91419457
86Abnormality of chromosome stability (HP:0003220)1.90780430
87IgA deficiency (HP:0002720)1.90303729
88Abnormality of cells of the erythroid lineage (HP:0012130)1.88770108
89Central scotoma (HP:0000603)1.88433964
90Optic disc pallor (HP:0000543)1.88363863
91Abnormality of renal excretion (HP:0011036)1.87137824
92Aplasia/hypoplasia of the uterus (HP:0008684)1.87083824
93Hypergammaglobulinemia (HP:0010702)1.86060510
94Multiple enchondromatosis (HP:0005701)1.85619749
95Oral leukoplakia (HP:0002745)1.84465907
96Intellectual disability, profound (HP:0002187)1.82907949
97Neoplasm of the tracheobronchial system (HP:0100552)1.82766138
98Abnormality of homocysteine metabolism (HP:0010919)1.82761277
99Homocystinuria (HP:0002156)1.82761277
100Conical tooth (HP:0000698)1.82605038

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ZAK4.99828956
2VRK24.01009279
3TAOK33.39530695
4MAP4K13.09932042
5TLK12.97421019
6TXK2.68708123
7SCYL22.51970628
8IKBKE2.09071175
9MAPKAPK31.95092540
10VRK11.95008665
11IKBKB1.92403525
12EIF2AK11.91123823
13KDR1.90254859
14NUAK11.88161231
15MAP3K141.80469789
16TEC1.76863515
17ADRBK21.74778964
18TBK11.74284436
19BMPR21.73197274
20ITK1.61385466
21WNK41.48863266
22CSNK1G31.45904397
23MAP3K121.42314647
24FRK1.41967282
25GRK61.40033292
26EIF2AK31.38349430
27PIK3CA1.37366481
28PLK41.34627055
29CSNK1G21.33560124
30MAP3K111.30351126
31STK391.29808098
32STK161.28690220
33MAPK111.27964801
34DAPK11.24909945
35IRAK41.23297902
36PIK3CG1.21197044
37JAK31.19294545
38CHEK21.19175042
39MAPKAPK51.15404589
40NME11.15355258
41KIT1.14849406
42GRK11.08437922
43RPS6KA51.07245772
44IRAK11.06982471
45CDC71.05394693
46EIF2AK21.04674386
47LCK1.01052719
48NEK10.99952910
49CSNK1A1L0.97269460
50BRSK20.94731931
51TIE10.92847746
52CSNK1G10.92471737
53PRKCQ0.92034775
54PLK30.89929154
55SYK0.84372025
56MAP2K20.78350091
57SRPK10.75693633
58IRAK20.75437175
59CCNB10.74203694
60MAP3K50.70700176
61FES0.70543756
62DYRK30.67415801
63OXSR10.67085503
64CDK80.66900475
65TAF10.64595651
66IGF1R0.64045645
67GRK70.62369539
68BTK0.56939468
69CSF1R0.56032780
70TESK20.55520290
71CHUK0.54557759
72WEE10.54224788
73TTK0.53849984
74MKNK10.52925030
75MAPK70.52494876
76PINK10.50946194
77INSRR0.49817432
78ERBB30.47686512
79PHKG10.47464839
80PHKG20.47464839
81MAP4K20.46511806
82TYK20.45507789
83SIK20.45447400
84ADRBK10.44595416
85ABL10.44056476
86RIPK40.43592281
87ATR0.42236935
88MST40.40775395
89TRPM70.39103832
90BCKDK0.39027515
91MYLK0.37307621
92ATM0.34257754
93LYN0.33753773
94PLK20.32574210
95TAOK20.32190439
96ZAP700.30730091
97PTK2B0.30130378
98BMPR1B0.29445815
99RPS6KA10.28677307
100CSNK2A20.27872600

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.32644734
2Asthma_Homo sapiens_hsa053103.69015745
3Allograft rejection_Homo sapiens_hsa053303.34464279
4Autoimmune thyroid disease_Homo sapiens_hsa053203.22946908
5Graft-versus-host disease_Homo sapiens_hsa053323.07812130
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.94740586
7Selenocompound metabolism_Homo sapiens_hsa004502.89885863
8Antigen processing and presentation_Homo sapiens_hsa046122.50172085
9Vitamin B6 metabolism_Homo sapiens_hsa007502.46761230
10Homologous recombination_Homo sapiens_hsa034402.45663179
11Proteasome_Homo sapiens_hsa030502.31809439
12Oxidative phosphorylation_Homo sapiens_hsa001902.12910768
13Ribosome_Homo sapiens_hsa030102.11830169
14Olfactory transduction_Homo sapiens_hsa047402.08767163
15Systemic lupus erythematosus_Homo sapiens_hsa053222.07894988
16Type I diabetes mellitus_Homo sapiens_hsa049402.02974477
17Protein export_Homo sapiens_hsa030601.92307815
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.74648200
19Viral myocarditis_Homo sapiens_hsa054161.73866081
20T cell receptor signaling pathway_Homo sapiens_hsa046601.69412710
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.69135745
22Rheumatoid arthritis_Homo sapiens_hsa053231.66003955
23Linoleic acid metabolism_Homo sapiens_hsa005911.63431825
24Parkinsons disease_Homo sapiens_hsa050121.61384966
25Fanconi anemia pathway_Homo sapiens_hsa034601.52493937
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47077906
27NF-kappa B signaling pathway_Homo sapiens_hsa040641.40297128
28Nitrogen metabolism_Homo sapiens_hsa009101.39246339
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.35832388
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.31546684
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.29880847
32Hematopoietic cell lineage_Homo sapiens_hsa046401.29435190
33Basal transcription factors_Homo sapiens_hsa030221.25382849
34Leishmaniasis_Homo sapiens_hsa051401.24466261
35Nucleotide excision repair_Homo sapiens_hsa034201.16818835
36RNA polymerase_Homo sapiens_hsa030201.14669774
37Spliceosome_Homo sapiens_hsa030401.13305837
38NOD-like receptor signaling pathway_Homo sapiens_hsa046211.12398297
39Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.10749399
40One carbon pool by folate_Homo sapiens_hsa006701.05902252
41Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.05853692
42Caffeine metabolism_Homo sapiens_hsa002321.01752661
43Staphylococcus aureus infection_Homo sapiens_hsa051501.01124723
44RNA degradation_Homo sapiens_hsa030181.01121367
45Alzheimers disease_Homo sapiens_hsa050100.97115829
46RNA transport_Homo sapiens_hsa030130.96720762
47Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.92699865
48DNA replication_Homo sapiens_hsa030300.92559985
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.90876846
50Ether lipid metabolism_Homo sapiens_hsa005650.84252791
51Huntingtons disease_Homo sapiens_hsa050160.84083276
52Base excision repair_Homo sapiens_hsa034100.81592370
53Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77663538
54Butanoate metabolism_Homo sapiens_hsa006500.77461185
55Non-homologous end-joining_Homo sapiens_hsa034500.77286377
56Herpes simplex infection_Homo sapiens_hsa051680.76798028
57Arachidonic acid metabolism_Homo sapiens_hsa005900.75072461
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.75007206
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.70169640
60Measles_Homo sapiens_hsa051620.68839701
61Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68120066
62Collecting duct acid secretion_Homo sapiens_hsa049660.67842340
63Mismatch repair_Homo sapiens_hsa034300.66524851
64Cardiac muscle contraction_Homo sapiens_hsa042600.63595557
65Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59613825
66Regulation of autophagy_Homo sapiens_hsa041400.56723088
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55811062
68Phototransduction_Homo sapiens_hsa047440.55603549
69Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55033003
70Pyrimidine metabolism_Homo sapiens_hsa002400.50964733
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50593274
72Alcoholism_Homo sapiens_hsa050340.50403168
73Chemical carcinogenesis_Homo sapiens_hsa052040.47309055
74Purine metabolism_Homo sapiens_hsa002300.47034927
75RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45679385
76Epstein-Barr virus infection_Homo sapiens_hsa051690.44565265
77Toxoplasmosis_Homo sapiens_hsa051450.43605835
78Viral carcinogenesis_Homo sapiens_hsa052030.40882671
79Shigellosis_Homo sapiens_hsa051310.39830445
80Tuberculosis_Homo sapiens_hsa051520.37284365
81TNF signaling pathway_Homo sapiens_hsa046680.35576404
82Legionellosis_Homo sapiens_hsa051340.35378831
83Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34223954
84Taste transduction_Homo sapiens_hsa047420.33799804
85Influenza A_Homo sapiens_hsa051640.33708180
86Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32590282
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31953382
88Retinol metabolism_Homo sapiens_hsa008300.29576390
89Malaria_Homo sapiens_hsa051440.27814757
90B cell receptor signaling pathway_Homo sapiens_hsa046620.26885694
91Fat digestion and absorption_Homo sapiens_hsa049750.26854224
92Tryptophan metabolism_Homo sapiens_hsa003800.25783266
93Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.25556787
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.23175180
95Nicotine addiction_Homo sapiens_hsa050330.21732329
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.19266284
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.18500359
98Metabolic pathways_Homo sapiens_hsa011000.17834596
99Pertussis_Homo sapiens_hsa051330.15426952
100Apoptosis_Homo sapiens_hsa042100.15152354

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »