RPL7P44

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine metabolic process (GO:0046087)6.52624060
2cytidine catabolic process (GO:0006216)6.52624060
3cytidine deamination (GO:0009972)6.52624060
4DNA deamination (GO:0045006)6.44804017
5ribosomal small subunit assembly (GO:0000028)6.28717480
6regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.99541362
7pyrimidine ribonucleoside catabolic process (GO:0046133)5.66107245
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.36835165
9energy coupled proton transport, down electrochemical gradient (GO:0015985)5.04025554
10ATP synthesis coupled proton transport (GO:0015986)5.04025554
11viral transcription (GO:0019083)4.85889665
12translational termination (GO:0006415)4.66237430
13mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.38676486
14SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.30019100
15cotranslational protein targeting to membrane (GO:0006613)4.22408097
16protein targeting to ER (GO:0045047)4.21982804
17translational elongation (GO:0006414)4.18935410
18respiratory electron transport chain (GO:0022904)4.07740123
19electron transport chain (GO:0022900)4.02335329
20establishment of protein localization to endoplasmic reticulum (GO:0072599)4.00522848
21protein localization to endoplasmic reticulum (GO:0070972)3.99046166
22protein neddylation (GO:0045116)3.85528729
23positive thymic T cell selection (GO:0045059)3.84755873
24maturation of SSU-rRNA (GO:0030490)3.79404217
25Arp2/3 complex-mediated actin nucleation (GO:0034314)3.75711502
26positive T cell selection (GO:0043368)3.74790490
27sequestering of actin monomers (GO:0042989)3.63997904
28antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.51912319
29viral life cycle (GO:0019058)3.51523932
30actin nucleation (GO:0045010)3.47728146
31cellular protein complex disassembly (GO:0043624)3.45717092
32response to pheromone (GO:0019236)3.42663101
33ribosomal large subunit biogenesis (GO:0042273)3.39655195
34negative regulation by host of viral transcription (GO:0043922)3.37919833
35negative regulation of T cell apoptotic process (GO:0070233)3.31207396
36positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.28795946
37nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.24908892
38regulation of activation of Janus kinase activity (GO:0010533)3.24786145
39ribosomal small subunit biogenesis (GO:0042274)3.19538328
40regulation of regulatory T cell differentiation (GO:0045589)3.18947627
41translational initiation (GO:0006413)3.17768376
42protein complex biogenesis (GO:0070271)3.17597945
43establishment of protein localization to mitochondrial membrane (GO:0090151)3.12758780
44regulation of B cell receptor signaling pathway (GO:0050855)3.12155587
45negative T cell selection (GO:0043383)3.08558414
46tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.06426092
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.06426092
48positive regulation of interleukin-8 secretion (GO:2000484)3.05028441
49platelet dense granule organization (GO:0060155)3.04900186
50positive regulation of calcium-mediated signaling (GO:0050850)3.04541453
51translation (GO:0006412)2.99817080
52pyrimidine nucleoside catabolic process (GO:0046135)2.99597650
53positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.97449870
54positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.97313464
55mast cell activation (GO:0045576)2.93512444
56positive regulation of B cell differentiation (GO:0045579)2.93096670
57response to interferon-beta (GO:0035456)2.92983766
58positive regulation of natural killer cell mediated immunity (GO:0002717)2.92966866
59hydrogen ion transmembrane transport (GO:1902600)2.91466596
60positive regulation of T cell mediated cytotoxicity (GO:0001916)2.91185802
61eosinophil chemotaxis (GO:0048245)2.89546682
62regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.88444104
63nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.85795849
64pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.84874903
65ATP biosynthetic process (GO:0006754)2.83398387
66regulation of T cell receptor signaling pathway (GO:0050856)2.82388748
67proteasome assembly (GO:0043248)2.82267157
68regulation of interleukin-8 secretion (GO:2000482)2.80310128
69T cell migration (GO:0072678)2.79904012
70mitochondrial respiratory chain complex assembly (GO:0033108)2.79518909
71regulation of cellular amino acid metabolic process (GO:0006521)2.79273013
72proton transport (GO:0015992)2.77119470
73protein complex disassembly (GO:0043241)2.76333253
74DNA demethylation (GO:0080111)2.74708388
75cytolysis (GO:0019835)2.71582187
76T cell receptor signaling pathway (GO:0050852)2.71469773
77hydrogen transport (GO:0006818)2.71433888
78protein targeting to membrane (GO:0006612)2.70574708
79water-soluble vitamin biosynthetic process (GO:0042364)2.69236723
80regulation of leukocyte mediated cytotoxicity (GO:0001910)2.68219268
81positive regulation of alpha-beta T cell proliferation (GO:0046641)2.67932177
82negative regulation of viral genome replication (GO:0045071)2.67656411
83DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.67388866
84positive regulation of defense response to virus by host (GO:0002230)2.65912688
85eosinophil migration (GO:0072677)2.65009098
86mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.64685387
87mitochondrial respiratory chain complex I assembly (GO:0032981)2.64685387
88NADH dehydrogenase complex assembly (GO:0010257)2.64685387
89exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.64494495
90macromolecular complex disassembly (GO:0032984)2.64429485
91positive regulation of tolerance induction (GO:0002645)2.63330472
92regulation of T cell mediated cytotoxicity (GO:0001914)2.62917072
93regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.61901844
94GPI anchor metabolic process (GO:0006505)2.61779187
95mast cell activation involved in immune response (GO:0002279)2.61437722
96mast cell degranulation (GO:0043303)2.61437722
97antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.60961367
98positive regulation of cell killing (GO:0031343)2.60790446
99T cell costimulation (GO:0031295)2.60405783
100regulation of chronic inflammatory response (GO:0002676)2.60237748

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.29303862
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.62175999
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.42556725
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.20823661
5E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.11519927
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.01431320
7VDR_22108803_ChIP-Seq_LS180_Human2.95926524
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.92674897
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.87773800
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.70811534
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.49090416
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.41619987
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.34636978
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.24235585
15VDR_23849224_ChIP-Seq_CD4+_Human2.23904758
16EZH2_22144423_ChIP-Seq_EOC_Human2.16513234
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.12411846
18ZNF274_21170338_ChIP-Seq_K562_Hela2.12131202
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.11497676
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.05582870
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.98599467
22IGF1R_20145208_ChIP-Seq_DFB_Human1.92855191
23ETS1_20019798_ChIP-Seq_JURKAT_Human1.90927456
24MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85507818
25ELK1_19687146_ChIP-ChIP_HELA_Human1.77470221
26MYB_26560356_Chip-Seq_TH2_Human1.67679549
27FOXP3_21729870_ChIP-Seq_TREG_Human1.64982638
28IRF8_21731497_ChIP-ChIP_J774_Mouse1.63850164
29MYC_18940864_ChIP-ChIP_HL60_Human1.62680244
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.61953434
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.53156964
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.50770506
33TP53_22573176_ChIP-Seq_HFKS_Human1.49652827
34LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.49378719
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.44781571
36GATA3_26560356_Chip-Seq_TH2_Human1.44581985
37AR_20517297_ChIP-Seq_VCAP_Human1.44173544
38RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39588954
39FOXA1_27270436_Chip-Seq_PROSTATE_Human1.38159944
40FOXA1_25329375_ChIP-Seq_VCAP_Human1.38159944
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.35719426
42EWS_26573619_Chip-Seq_HEK293_Human1.34541475
43FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.33619596
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.32939850
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30340459
46FUS_26573619_Chip-Seq_HEK293_Human1.30061386
47NANOG_20526341_ChIP-Seq_ESCs_Human1.29841414
48RUNX_20019798_ChIP-Seq_JUKART_Human1.29653996
49PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.28903262
50RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.26845568
51ER_23166858_ChIP-Seq_MCF-7_Human1.26814347
52GATA3_27048872_Chip-Seq_THYMUS_Human1.25320991
53NCOR_22424771_ChIP-Seq_293T_Human1.22175753
54AUTS2_25519132_ChIP-Seq_293T-REX_Human1.21148721
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20385246
56PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.19356745
57SOX2_19829295_ChIP-Seq_ESCs_Human1.18748852
58NANOG_19829295_ChIP-Seq_ESCs_Human1.18748852
59SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.18525541
60TAF2_19829295_ChIP-Seq_ESCs_Human1.18397443
61PCGF2_27294783_Chip-Seq_NPCs_Mouse1.17773852
62GATA3_21878914_ChIP-Seq_MCF-7_Human1.17204721
63EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.17012692
64HTT_18923047_ChIP-ChIP_STHdh_Human1.16378641
65RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.15069048
66GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13340335
67ERG_20517297_ChIP-Seq_VCAP_Human1.12983818
68FOXA1_21572438_ChIP-Seq_LNCaP_Human1.12700195
69CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.11963341
70TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.09382960
71P300_19829295_ChIP-Seq_ESCs_Human1.09205405
72BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08854737
73TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08811142
74IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.07987482
75CBP_20019798_ChIP-Seq_JUKART_Human1.07987482
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.07426483
77CREB1_15753290_ChIP-ChIP_HEK293T_Human1.05653082
78ETV2_25802403_ChIP-Seq_MESCs_Mouse1.05398196
79MYC_19829295_ChIP-Seq_ESCs_Human1.04983785
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.03267689
81BCAT_22108803_ChIP-Seq_LS180_Human1.00896894
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00847209
83POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99861417
84ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99746477
85FOXH1_21741376_ChIP-Seq_EPCs_Human0.99576929
86BCL6_27268052_Chip-Seq_Bcells_Human0.99507164
87TAF15_26573619_Chip-Seq_HEK293_Human0.98640178
88GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.96672447
89MYC_18555785_ChIP-Seq_MESCs_Mouse0.96456622
90POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96334266
91SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.95743056
92FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95740601
93ELK1_22589737_ChIP-Seq_MCF10A_Human0.95506047
94CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.94899362
95SUZ12_27294783_Chip-Seq_NPCs_Mouse0.94895008
96GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.93851937
97PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93472133
98EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91954549
99STAT4_19710469_ChIP-ChIP_TH1__Mouse0.91818932
100GATA6_21074721_ChIP-Seq_CACO-2_Human0.91062812

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.03750311
2MP0009379_abnormal_foot_pigmentation4.41853844
3MP0001835_abnormal_antigen_presentation2.82792337
4MP0006292_abnormal_olfactory_placode2.78691344
5MP0009785_altered_susceptibility_to2.69091868
6MP0009333_abnormal_splenocyte_physiolog2.14211250
7MP0006072_abnormal_retinal_apoptosis2.10922062
8MP0001800_abnormal_humoral_immune2.06306098
9MP0002148_abnormal_hypersensitivity_rea1.97513952
10MP0005000_abnormal_immune_tolerance1.96058071
11MP0003763_abnormal_thymus_physiology1.95984600
12MP0000372_irregular_coat_pigmentation1.94567451
13MP0002837_dystrophic_cardiac_calcinosis1.92872042
14MP0003646_muscle_fatigue1.92683527
15MP0005645_abnormal_hypothalamus_physiol1.91154382
16MP0002102_abnormal_ear_morphology1.86278510
17MP0004147_increased_porphyrin_level1.84381429
18MP0002723_abnormal_immune_serum1.74245493
19MP0005377_hearing/vestibular/ear_phenot1.72780016
20MP0003878_abnormal_ear_physiology1.72780016
21MP0002166_altered_tumor_susceptibility1.72726315
22MP0005075_abnormal_melanosome_morpholog1.70066616
23MP0008872_abnormal_physiological_respon1.69667402
24MP0002420_abnormal_adaptive_immunity1.68145054
25MP0008875_abnormal_xenobiotic_pharmacok1.67417256
26MP0005025_abnormal_response_to1.67131594
27MP0001819_abnormal_immune_cell1.63109892
28MP0003866_abnormal_defecation1.62475308
29MP0000685_abnormal_immune_system1.62295270
30MP0005551_abnormal_eye_electrophysiolog1.62278087
31MP0002138_abnormal_hepatobiliary_system1.60429532
32MP0001790_abnormal_immune_system1.56199924
33MP0005387_immune_system_phenotype1.56199924
34MP0005646_abnormal_pituitary_gland1.53480021
35MP0001873_stomach_inflammation1.51798244
36MP0004145_abnormal_muscle_electrophysio1.50197350
37MP0002006_tumorigenesis1.47470058
38MP0002452_abnormal_antigen_presenting1.46734719
39MP0001968_abnormal_touch/_nociception1.43281367
40MP0010155_abnormal_intestine_physiology1.37047581
41MP0003011_delayed_dark_adaptation1.33924478
42MP0006082_CNS_inflammation1.33737446
43MP0002736_abnormal_nociception_after1.32086289
44MP0001905_abnormal_dopamine_level1.31407596
45MP0005389_reproductive_system_phenotype1.31142760
46MP0008877_abnormal_DNA_methylation1.28602660
47MP0000716_abnormal_immune_system1.27757190
48MP0001919_abnormal_reproductive_system1.27099813
49MP0004885_abnormal_endolymph1.27053707
50MP0005084_abnormal_gallbladder_morpholo1.25679508
51MP0002876_abnormal_thyroid_physiology1.23571137
52MP0005253_abnormal_eye_physiology1.22787443
53MP0002398_abnormal_bone_marrow1.19168580
54MP0001986_abnormal_taste_sensitivity1.18692908
55MP0003724_increased_susceptibility_to1.17560107
56MP0001485_abnormal_pinna_reflex1.17130922
57MP0008995_early_reproductive_senescence1.16574911
58MP0002277_abnormal_respiratory_mucosa1.16475948
59MP0003806_abnormal_nucleotide_metabolis1.13585921
60MP0004142_abnormal_muscle_tone1.13000005
61MP0002163_abnormal_gland_morphology1.10840000
62MP0001845_abnormal_inflammatory_respons1.09070158
63MP0002234_abnormal_pharynx_morphology1.08895185
64MP0002095_abnormal_skin_pigmentation1.08294585
65MP0002160_abnormal_reproductive_system1.05704432
66MP0002405_respiratory_system_inflammati1.05585123
67MP0005410_abnormal_fertilization1.04223050
68MP0009764_decreased_sensitivity_to1.03815568
69MP0003195_calcinosis1.03114079
70MP0003880_abnormal_central_pattern1.02445775
71MP0001764_abnormal_homeostasis1.01606323
72MP0000689_abnormal_spleen_morphology1.01003784
73MP0003567_abnormal_fetal_cardiomyocyte0.99854544
74MP0006276_abnormal_autonomic_nervous0.98717863
75MP0002638_abnormal_pupillary_reflex0.96564541
76MP0002429_abnormal_blood_cell0.92241828
77MP0003787_abnormal_imprinting0.90884637
78MP0002722_abnormal_immune_system0.89377308
79MP0003252_abnormal_bile_duct0.89102393
80MP0008469_abnormal_protein_level0.88327448
81MP0003786_premature_aging0.87124366
82MP0002419_abnormal_innate_immunity0.85417801
83MP0005636_abnormal_mineral_homeostasis0.85364420
84MP0001501_abnormal_sleep_pattern0.83638321
85MP0002933_joint_inflammation0.82660479
86MP0000703_abnormal_thymus_morphology0.81603401
87MP0005085_abnormal_gallbladder_physiolo0.81468093
88MP0000631_abnormal_neuroendocrine_gland0.80950195
89MP0008789_abnormal_olfactory_epithelium0.80821407
90MP0005379_endocrine/exocrine_gland_phen0.79240281
91MP0001293_anophthalmia0.78697232
92MP0002733_abnormal_thermal_nociception0.78168071
93MP0002272_abnormal_nervous_system0.77976156
94MP0003137_abnormal_impulse_conducting0.77920648
95MP0003136_yellow_coat_color0.76848753
96MP0001970_abnormal_pain_threshold0.76359788
97MP0001765_abnormal_ion_homeostasis0.74160766
98MP0010386_abnormal_urinary_bladder0.73581849
99MP0009745_abnormal_behavioral_response0.72892604
100MP0002653_abnormal_ependyma_morphology0.71343305

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)4.64455735
2Acute necrotizing encephalopathy (HP:0006965)4.11145339
3Mitochondrial inheritance (HP:0001427)4.08458832
4Congenital stationary night blindness (HP:0007642)3.78020464
5Severe combined immunodeficiency (HP:0004430)3.72853580
6IgG deficiency (HP:0004315)3.68866547
7Abnormal mitochondria in muscle tissue (HP:0008316)3.68152183
8Hypoproteinemia (HP:0003075)3.60742178
9Increased hepatocellular lipid droplets (HP:0006565)3.59006090
10T lymphocytopenia (HP:0005403)3.55747507
11Elevated erythrocyte sedimentation rate (HP:0003565)3.55443352
12Abnormality of T cell number (HP:0011839)3.48183472
13Absent rod-and cone-mediated responses on ERG (HP:0007688)3.47726416
14Increased CSF lactate (HP:0002490)3.44650890
15Progressive macrocephaly (HP:0004481)3.43438884
163-Methylglutaconic aciduria (HP:0003535)3.40114614
17Acute encephalopathy (HP:0006846)3.39336523
18Hepatocellular necrosis (HP:0001404)3.33022141
19Lipid accumulation in hepatocytes (HP:0006561)3.25414306
20Pancreatic cysts (HP:0001737)3.18654266
21Abnormality of B cell number (HP:0010975)3.17419706
22Thyroiditis (HP:0100646)3.15464743
23Increased intramyocellular lipid droplets (HP:0012240)3.12830175
24Abnormality of cells of the erythroid lineage (HP:0012130)3.09575993
25Hepatic necrosis (HP:0002605)3.06374766
26Renal Fanconi syndrome (HP:0001994)3.02822749
27Abnormal number of erythroid precursors (HP:0012131)2.95429204
28Abnormal rod and cone electroretinograms (HP:0008323)2.95377729
29Reticulocytopenia (HP:0001896)2.84441050
30Combined immunodeficiency (HP:0005387)2.77930507
31Cerebral edema (HP:0002181)2.73841153
32B lymphocytopenia (HP:0010976)2.72311905
33Abolished electroretinogram (ERG) (HP:0000550)2.72150062
34Pancreatic fibrosis (HP:0100732)2.72048673
35True hermaphroditism (HP:0010459)2.69231403
36Exertional dyspnea (HP:0002875)2.64275438
37Abnormality of T cells (HP:0002843)2.62447078
38Decreased central vision (HP:0007663)2.61956166
39Autoimmune hemolytic anemia (HP:0001890)2.60273546
40Increased muscle lipid content (HP:0009058)2.59850910
41Attenuation of retinal blood vessels (HP:0007843)2.58068279
42Abnormality of the prostate (HP:0008775)2.57428213
43Increased IgM level (HP:0003496)2.54434410
44Optic disc pallor (HP:0000543)2.52615480
45Molar tooth sign on MRI (HP:0002419)2.50964488
46Abnormality of midbrain morphology (HP:0002418)2.50964488
47Abnormality of eosinophils (HP:0001879)2.48171218
48Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.47842733
49Congenital, generalized hypertrichosis (HP:0004540)2.44318922
50Macrocytic anemia (HP:0001972)2.43423132
51Stomatitis (HP:0010280)2.43062544
52Generalized aminoaciduria (HP:0002909)2.34146796
53Pancytopenia (HP:0001876)2.28550843
54Colon cancer (HP:0003003)2.25614600
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.18869885
56Methylmalonic acidemia (HP:0002912)2.16516564
57Panhypogammaglobulinemia (HP:0003139)2.15155067
58Type 2 muscle fiber atrophy (HP:0003554)2.14688468
59Abnormality of the renal cortex (HP:0011035)2.13253135
60Abnormality of urine glucose concentration (HP:0011016)2.11517518
61Glycosuria (HP:0003076)2.11517518
62Chronic diarrhea (HP:0002028)2.11451903
63Increased serum lactate (HP:0002151)2.11441329
64Lactic acidosis (HP:0003128)2.11069716
65Decreased electroretinogram (ERG) amplitude (HP:0000654)2.10838190
66Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.10208526
67Decreased activity of mitochondrial respiratory chain (HP:0008972)2.10208526
68Renal cortical cysts (HP:0000803)2.08675839
69Pendular nystagmus (HP:0012043)2.08438282
70Constricted visual fields (HP:0001133)2.05441779
71Lethargy (HP:0001254)2.04027521
72Nephronophthisis (HP:0000090)2.01662872
73Medial flaring of the eyebrow (HP:0010747)2.00426349
74Eosinophilia (HP:0001880)1.96451004
75Abnormal albumin level (HP:0012116)1.95736836
76Hypoalbuminemia (HP:0003073)1.95736836
77Abnormality of renal resorption (HP:0011038)1.94932925
78Encephalitis (HP:0002383)1.92158250
79Oral leukoplakia (HP:0002745)1.91937064
80Agammaglobulinemia (HP:0004432)1.90390123
81Respiratory failure (HP:0002878)1.88371813
82Pallor (HP:0000980)1.87394979
83Absent thumb (HP:0009777)1.86272937
84Methylmalonic aciduria (HP:0012120)1.86119115
85Stenosis of the external auditory canal (HP:0000402)1.85396500
86Hyperphosphaturia (HP:0003109)1.84003072
87Muscle fiber atrophy (HP:0100295)1.80847880
88Hyperglycinemia (HP:0002154)1.80661430
89Type II lissencephaly (HP:0007260)1.79480081
90Leukocytosis (HP:0001974)1.79379129
91Abnormal delayed hypersensitivity skin test (HP:0002963)1.78284428
92Exercise intolerance (HP:0003546)1.77040007
93Hypoplasia of the thymus (HP:0000778)1.74928954
94Leukodystrophy (HP:0002415)1.74560222
95Recurrent bronchitis (HP:0002837)1.73826593
96Cystic liver disease (HP:0006706)1.73552102
97Respiratory difficulties (HP:0002880)1.72823882
98Abnormality of dicarboxylic acid metabolism (HP:0010995)1.72155326
99Dicarboxylic aciduria (HP:0003215)1.72155326
100Sclerocornea (HP:0000647)1.70254710

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.81308451
2KDR4.25734249
3TESK23.76406401
4CDK193.19890908
5BCKDK3.01617611
6VRK22.98982169
7TAOK32.54420881
8ZAK2.43415977
9ADRBK22.36171211
10GRK12.22603098
11ITK2.04069985
12MAP4K12.03967065
13MAP4K22.01046877
14TLK11.99623183
15STK161.83767172
16NUAK11.83288713
17VRK11.77580081
18MUSK1.67112960
19FRK1.65587724
20MAP3K121.64772291
21TEC1.56030600
22FES1.43524751
23PASK1.40797892
24SYK1.38177861
25BMPR1B1.33875643
26TIE11.30280344
27PINK11.21301197
28INSRR1.19592828
29KIT1.14629874
30MST41.11891082
31SCYL21.10760096
32GRK61.07437303
33BTK1.07355224
34WNK41.06421525
35PRKCQ1.02736574
36MYLK1.00728145
37GRK70.99622189
38LCK0.98954925
39NME10.96259063
40TNK20.95395207
41BMPR20.93744423
42LYN0.89135088
43LIMK10.87241079
44WNK30.86547733
45DYRK20.86138659
46OXSR10.84576162
47DAPK10.83549564
48TRPM70.83081635
49IKBKB0.83045368
50RPS6KA50.82189779
51DAPK20.78917877
52PIK3CG0.78426394
53CAMKK20.74912810
54ZAP700.73039017
55CSF1R0.72865406
56PIK3CA0.69676784
57CSK0.69404754
58BUB10.68600803
59DAPK30.68460015
60TESK10.63881649
61OBSCN0.63380917
62EIF2AK30.62850623
63ADRBK10.62153196
64RPS6KA40.61300888
65MAPK130.60490295
66ERBB30.59446969
67IKBKE0.57386375
68MATK0.55574761
69IGF1R0.53374789
70TAF10.50515154
71ILK0.50310201
72CSNK1G30.46991710
73PIM10.46990829
74CDK80.46253142
75PLK40.46125509
76MAP2K60.45428021
77MAP3K110.44800040
78PRKCA0.44038961
79CAMKK10.44001584
80MAPKAPK30.43652658
81PRKACA0.42594070
82GRK50.42396736
83MAP2K70.41765525
84MAPKAPK50.39705593
85MKNK10.38422945
86CSNK2A10.36186270
87HCK0.35056611
88CSNK2A20.34944913
89MAP3K40.34776129
90PRKCH0.34664774
91FYN0.33801315
92JAK30.32893089
93PRKCE0.32196586
94CSNK1G10.30586527
95ROCK10.30574665
96CAMK2A0.29633368
97EPHA40.28943169
98CAMK10.28659462
99PRKCD0.27433055
100CSNK1A10.25871017

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.10993597
2Primary immunodeficiency_Homo sapiens_hsa053403.79998204
3Oxidative phosphorylation_Homo sapiens_hsa001903.77908784
4Proteasome_Homo sapiens_hsa030503.57859219
5Parkinsons disease_Homo sapiens_hsa050123.10503157
6Allograft rejection_Homo sapiens_hsa053303.08306925
7Graft-versus-host disease_Homo sapiens_hsa053323.03967067
8Autoimmune thyroid disease_Homo sapiens_hsa053203.01747852
9Asthma_Homo sapiens_hsa053102.89151780
10Type I diabetes mellitus_Homo sapiens_hsa049402.45003420
11Antigen processing and presentation_Homo sapiens_hsa046122.39833145
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.31800299
13Alzheimers disease_Homo sapiens_hsa050102.05501015
14Protein export_Homo sapiens_hsa030602.02746805
15Huntingtons disease_Homo sapiens_hsa050161.93302264
16RNA polymerase_Homo sapiens_hsa030201.89661810
17Hematopoietic cell lineage_Homo sapiens_hsa046401.89646043
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88394790
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.87327554
20Phototransduction_Homo sapiens_hsa047441.85788491
21Cardiac muscle contraction_Homo sapiens_hsa042601.79421260
22Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.66208615
23Rheumatoid arthritis_Homo sapiens_hsa053231.53656020
24Linoleic acid metabolism_Homo sapiens_hsa005911.47456012
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.40262707
26Homologous recombination_Homo sapiens_hsa034401.35933130
27Caffeine metabolism_Homo sapiens_hsa002321.27854132
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.22712997
29Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.19482299
30Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.19111460
31Nitrogen metabolism_Homo sapiens_hsa009101.12649728
32T cell receptor signaling pathway_Homo sapiens_hsa046601.10209936
33Viral myocarditis_Homo sapiens_hsa054161.06392967
34Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.01428986
35RNA degradation_Homo sapiens_hsa030180.99778890
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97784326
37Staphylococcus aureus infection_Homo sapiens_hsa051500.91927556
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.91559468
39Olfactory transduction_Homo sapiens_hsa047400.90929561
40Systemic lupus erythematosus_Homo sapiens_hsa053220.86717269
41Pyrimidine metabolism_Homo sapiens_hsa002400.83950769
42Peroxisome_Homo sapiens_hsa041460.82544541
43Retinol metabolism_Homo sapiens_hsa008300.82322163
44Chemical carcinogenesis_Homo sapiens_hsa052040.81832731
45Fanconi anemia pathway_Homo sapiens_hsa034600.80150628
46Butanoate metabolism_Homo sapiens_hsa006500.79345325
47Steroid hormone biosynthesis_Homo sapiens_hsa001400.75422658
48Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74911811
49One carbon pool by folate_Homo sapiens_hsa006700.74101409
50Arachidonic acid metabolism_Homo sapiens_hsa005900.72516959
51Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.69446156
52Propanoate metabolism_Homo sapiens_hsa006400.69145882
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.67483549
54Purine metabolism_Homo sapiens_hsa002300.66326865
55Ether lipid metabolism_Homo sapiens_hsa005650.65894801
56Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.63409125
57Basal transcription factors_Homo sapiens_hsa030220.63260564
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63151473
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61573278
60Nucleotide excision repair_Homo sapiens_hsa034200.60120525
61Taste transduction_Homo sapiens_hsa047420.57562059
62Mismatch repair_Homo sapiens_hsa034300.57544662
63NF-kappa B signaling pathway_Homo sapiens_hsa040640.55459698
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.54041210
65Tryptophan metabolism_Homo sapiens_hsa003800.53822609
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.53708562
67Fat digestion and absorption_Homo sapiens_hsa049750.51482506
68Spliceosome_Homo sapiens_hsa030400.51449732
69Malaria_Homo sapiens_hsa051440.50152634
70Measles_Homo sapiens_hsa051620.49434635
71DNA replication_Homo sapiens_hsa030300.49211931
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.46783428
73Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44829917
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.44274016
75Leishmaniasis_Homo sapiens_hsa051400.44222863
76Metabolic pathways_Homo sapiens_hsa011000.43720001
77Maturity onset diabetes of the young_Homo sapiens_hsa049500.42141736
78Collecting duct acid secretion_Homo sapiens_hsa049660.40678375
79SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40432834
80Regulation of autophagy_Homo sapiens_hsa041400.39023349
81Nicotine addiction_Homo sapiens_hsa050330.38851163
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36152654
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35039778
84RNA transport_Homo sapiens_hsa030130.32876567
85Vitamin digestion and absorption_Homo sapiens_hsa049770.31899872
86Herpes simplex infection_Homo sapiens_hsa051680.30900220
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29784771
88Salmonella infection_Homo sapiens_hsa051320.28108299
89Morphine addiction_Homo sapiens_hsa050320.27864883
90Base excision repair_Homo sapiens_hsa034100.27327549
91Salivary secretion_Homo sapiens_hsa049700.27244830
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.24069760
93Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.20665535
94African trypanosomiasis_Homo sapiens_hsa051430.19683076
95Selenocompound metabolism_Homo sapiens_hsa004500.18978416
96Ovarian steroidogenesis_Homo sapiens_hsa049130.18873276
97Mineral absorption_Homo sapiens_hsa049780.18659376
98Tyrosine metabolism_Homo sapiens_hsa003500.17863247
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.15579391
100Glutathione metabolism_Homo sapiens_hsa004800.14896979

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »