RPL7P8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.72861962
2DNA deamination (GO:0045006)5.07229576
3ATP synthesis coupled proton transport (GO:0015986)4.79873078
4energy coupled proton transport, down electrochemical gradient (GO:0015985)4.79873078
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.42904527
6mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.27992743
7behavioral response to nicotine (GO:0035095)4.00347415
8viral transcription (GO:0019083)3.99756084
9protein neddylation (GO:0045116)3.88821240
10translational termination (GO:0006415)3.82991449
11kynurenine metabolic process (GO:0070189)3.79307244
12maturation of SSU-rRNA (GO:0030490)3.77625355
13respiratory electron transport chain (GO:0022904)3.74429262
14electron transport chain (GO:0022900)3.73260704
15ribosomal large subunit biogenesis (GO:0042273)3.70958134
16regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.66150480
17tryptophan catabolic process (GO:0006569)3.50497344
18indole-containing compound catabolic process (GO:0042436)3.50497344
19indolalkylamine catabolic process (GO:0046218)3.50497344
20translational elongation (GO:0006414)3.48202724
21SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.48047121
22protein complex biogenesis (GO:0070271)3.43057361
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.42959736
24mitochondrial respiratory chain complex I assembly (GO:0032981)3.42959736
25NADH dehydrogenase complex assembly (GO:0010257)3.42959736
26cotranslational protein targeting to membrane (GO:0006613)3.41658880
27protein targeting to ER (GO:0045047)3.40094892
28tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.35305600
29RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.35305600
30negative regulation of heart rate (GO:0010459)3.30227597
31chaperone-mediated protein transport (GO:0072321)3.30123277
32protein localization to endoplasmic reticulum (GO:0070972)3.27927615
33amine catabolic process (GO:0009310)3.27283288
34cellular biogenic amine catabolic process (GO:0042402)3.27283288
35cytidine metabolic process (GO:0046087)3.25326968
36cytidine catabolic process (GO:0006216)3.25326968
37cytidine deamination (GO:0009972)3.25326968
38indolalkylamine metabolic process (GO:0006586)3.23393619
39establishment of protein localization to endoplasmic reticulum (GO:0072599)3.22125943
40platelet dense granule organization (GO:0060155)3.21259859
41water-soluble vitamin biosynthetic process (GO:0042364)3.12524540
42tryptophan metabolic process (GO:0006568)3.07920383
43nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.07436157
44mitochondrial respiratory chain complex assembly (GO:0033108)3.05868824
45epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.99967590
46exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.96672338
47cellular ketone body metabolic process (GO:0046950)2.96367593
48positive regulation of prostaglandin secretion (GO:0032308)2.95585812
49ribosomal small subunit biogenesis (GO:0042274)2.94135313
50GPI anchor metabolic process (GO:0006505)2.89825526
51negative regulation of mast cell activation (GO:0033004)2.89792038
52cornea development in camera-type eye (GO:0061303)2.88687185
53base-excision repair, AP site formation (GO:0006285)2.85961164
54negative regulation of telomere maintenance (GO:0032205)2.84208198
55viral life cycle (GO:0019058)2.83698050
56hydrogen ion transmembrane transport (GO:1902600)2.83374684
57parturition (GO:0007567)2.81113287
58proton transport (GO:0015992)2.79302160
59establishment of protein localization to mitochondrial membrane (GO:0090151)2.77383994
60L-fucose metabolic process (GO:0042354)2.74662064
61L-fucose catabolic process (GO:0042355)2.74662064
62fucose catabolic process (GO:0019317)2.74662064
63hydrogen transport (GO:0006818)2.74446662
64cellular protein complex disassembly (GO:0043624)2.73959302
65positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.73617941
66piRNA metabolic process (GO:0034587)2.70533957
67ketone body metabolic process (GO:1902224)2.68375652
68ATP biosynthetic process (GO:0006754)2.66822847
69preassembly of GPI anchor in ER membrane (GO:0016254)2.66425462
70pyrimidine ribonucleoside catabolic process (GO:0046133)2.64667159
71protein-cofactor linkage (GO:0018065)2.64264693
72detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.64238284
73positive regulation of defense response to virus by host (GO:0002230)2.64184376
74translation (GO:0006412)2.61776918
75positive regulation of fatty acid transport (GO:2000193)2.60003148
76mannosylation (GO:0097502)2.59365480
77dopamine transport (GO:0015872)2.59164981
78nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.57956252
79GPI anchor biosynthetic process (GO:0006506)2.57614715
80pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.56531328
81translational initiation (GO:0006413)2.55905700
82respiratory chain complex IV assembly (GO:0008535)2.55879809
83behavioral response to ethanol (GO:0048149)2.55777426
84purine nucleoside triphosphate biosynthetic process (GO:0009145)2.55602671
85purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.55456134
86response to pheromone (GO:0019236)2.53007242
87rRNA catabolic process (GO:0016075)2.47597799
88ubiquinone biosynthetic process (GO:0006744)2.47215229
89negative regulation of T cell differentiation in thymus (GO:0033085)2.46519690
90regulation of thymocyte apoptotic process (GO:0070243)2.46181613
91endoderm formation (GO:0001706)2.46120353
92aldehyde catabolic process (GO:0046185)2.45354449
93RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.40761787
94positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.40753678
95mast cell activation (GO:0045576)2.40346190
96regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.35766245
97cytochrome complex assembly (GO:0017004)2.35198624
98axoneme assembly (GO:0035082)2.34334761
99photoreceptor cell development (GO:0042461)2.32381663
100regulation of cilium movement (GO:0003352)2.32140375

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.64302874
2VDR_22108803_ChIP-Seq_LS180_Human3.10128960
3GABP_17652178_ChIP-ChIP_JURKAT_Human2.99379719
4ZNF274_21170338_ChIP-Seq_K562_Hela2.72097690
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.64649623
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.45233641
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.43266255
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.38315343
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.31272747
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.22803104
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.19459133
12RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.14764030
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.05800312
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.00937386
15ELF1_17652178_ChIP-ChIP_JURKAT_Human1.96441330
16IGF1R_20145208_ChIP-Seq_DFB_Human1.93489003
17IRF8_22096565_ChIP-ChIP_GC-B_Human1.89692647
18TP53_22573176_ChIP-Seq_HFKS_Human1.75569172
19EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.74840696
20VDR_23849224_ChIP-Seq_CD4+_Human1.72942856
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68456149
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.64384504
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59611939
24PCGF2_27294783_Chip-Seq_NPCs_Mouse1.58873028
25IRF1_19129219_ChIP-ChIP_H3396_Human1.57893496
26FOXA1_25329375_ChIP-Seq_VCAP_Human1.56256411
27FOXA1_27270436_Chip-Seq_PROSTATE_Human1.56256411
28ETS1_20019798_ChIP-Seq_JURKAT_Human1.55046317
29ER_23166858_ChIP-Seq_MCF-7_Human1.52210625
30LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.51778414
31MYC_18940864_ChIP-ChIP_HL60_Human1.51335660
32AR_20517297_ChIP-Seq_VCAP_Human1.50511485
33EWS_26573619_Chip-Seq_HEK293_Human1.50005810
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.49788392
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.45192117
36GATA3_21878914_ChIP-Seq_MCF-7_Human1.44867677
37AUTS2_25519132_ChIP-Seq_293T-REX_Human1.42679010
38P300_19829295_ChIP-Seq_ESCs_Human1.42415405
39GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.41671281
40GBX2_23144817_ChIP-Seq_PC3_Human1.36357405
41ELK1_19687146_ChIP-ChIP_HELA_Human1.35251641
42CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.35163993
43IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.34921923
44GATA3_26560356_Chip-Seq_TH2_Human1.33659958
45FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.32548386
46TDRD3_21172665_ChIP-Seq_MCF-7_Human1.32458844
47TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.31442970
48CBP_20019798_ChIP-Seq_JUKART_Human1.30975973
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30975973
50FUS_26573619_Chip-Seq_HEK293_Human1.30714504
51NANOG_20526341_ChIP-Seq_ESCs_Human1.30457037
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30069530
53NCOR_22424771_ChIP-Seq_293T_Human1.28046919
54SOX2_19829295_ChIP-Seq_ESCs_Human1.27705365
55NANOG_19829295_ChIP-Seq_ESCs_Human1.27705365
56POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26333627
57FOXP3_21729870_ChIP-Seq_TREG_Human1.25174173
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.24246184
59SRF_21415370_ChIP-Seq_HL-1_Mouse1.23295989
60NFE2_27457419_Chip-Seq_LIVER_Mouse1.22772175
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21764428
62BCAT_22108803_ChIP-Seq_LS180_Human1.20308116
63TAF2_19829295_ChIP-Seq_ESCs_Human1.19140808
64CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18500164
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17360108
66PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14593455
67EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.14550344
68HOXB7_26014856_ChIP-Seq_BT474_Human1.14295150
69STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.14099102
70TAF15_26573619_Chip-Seq_HEK293_Human1.13623574
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.13285680
72FOXA1_21572438_ChIP-Seq_LNCaP_Human1.13183920
73FOXH1_21741376_ChIP-Seq_EPCs_Human1.12658754
74ERA_21632823_ChIP-Seq_H3396_Human1.09340385
75MYC_19829295_ChIP-Seq_ESCs_Human1.05388953
76TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.04768832
77PRDM14_20953172_ChIP-Seq_ESCs_Human1.04199413
78EZH2_27294783_Chip-Seq_NPCs_Mouse1.03936690
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03900324
80RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.03460446
81CBX2_27304074_Chip-Seq_ESCs_Mouse1.03268609
82IRF8_21731497_ChIP-ChIP_J774_Mouse1.02216398
83TCF4_22108803_ChIP-Seq_LS180_Human1.02157571
84REST_21632747_ChIP-Seq_MESCs_Mouse1.01941338
85EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01370045
86ERG_20517297_ChIP-Seq_VCAP_Human1.00393963
87CRX_20693478_ChIP-Seq_RETINA_Mouse1.00009994
88TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98618279
89EGR1_23403033_ChIP-Seq_LIVER_Mouse0.98015848
90STAT3_18555785_Chip-Seq_ESCs_Mouse0.95146318
91GATA6_21074721_ChIP-Seq_CACO-2_Human0.95008992
92NOTCH1_21737748_ChIP-Seq_TLL_Human0.93883276
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.93836819
94GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.93371699
95EZH2_27294783_Chip-Seq_ESCs_Mouse0.91792804
96E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.91655611
97RNF2_27304074_Chip-Seq_NSC_Mouse0.90909932
98P53_22387025_ChIP-Seq_ESCs_Mouse0.90545574
99TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90355976
100CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.89709278

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.95577357
2MP0009379_abnormal_foot_pigmentation3.74036276
3MP0005671_abnormal_response_to2.83958912
4MP0002138_abnormal_hepatobiliary_system2.61179116
5MP0003787_abnormal_imprinting2.43642295
6MP0001835_abnormal_antigen_presentation2.40223358
7MP0008875_abnormal_xenobiotic_pharmacok2.38256238
8MP0008877_abnormal_DNA_methylation2.27101178
9MP0005645_abnormal_hypothalamus_physiol2.26726616
10MP0006072_abnormal_retinal_apoptosis2.22835477
11MP0008872_abnormal_physiological_respon2.20630915
12MP0002163_abnormal_gland_morphology2.06090763
13MP0005075_abnormal_melanosome_morpholog2.04362620
14MP0003646_muscle_fatigue1.98640151
15MP0005646_abnormal_pituitary_gland1.97630462
16MP0001968_abnormal_touch/_nociception1.93560054
17MP0002736_abnormal_nociception_after1.87559907
18MP0004145_abnormal_muscle_electrophysio1.86213983
19MP0005084_abnormal_gallbladder_morpholo1.85420893
20MP0002102_abnormal_ear_morphology1.84091632
21MP0005551_abnormal_eye_electrophysiolog1.82410809
22MP0000372_irregular_coat_pigmentation1.81582010
23MP0004142_abnormal_muscle_tone1.79555228
24MP0004885_abnormal_endolymph1.72222345
25MP0004147_increased_porphyrin_level1.69114341
26MP0002876_abnormal_thyroid_physiology1.61811371
27MP0005085_abnormal_gallbladder_physiolo1.58828056
28MP0005377_hearing/vestibular/ear_phenot1.58662923
29MP0003878_abnormal_ear_physiology1.58662923
30MP0003252_abnormal_bile_duct1.57495855
31MP0002837_dystrophic_cardiac_calcinosis1.55925250
32MP0003724_increased_susceptibility_to1.52273035
33MP0002638_abnormal_pupillary_reflex1.51882688
34MP0003806_abnormal_nucleotide_metabolis1.48523277
35MP0002148_abnormal_hypersensitivity_rea1.48337965
36MP0008789_abnormal_olfactory_epithelium1.46986943
37MP0009764_decreased_sensitivity_to1.42004422
38MP0005389_reproductive_system_phenotype1.41544539
39MP0002160_abnormal_reproductive_system1.35157876
40MP0001800_abnormal_humoral_immune1.34348566
41MP0009785_altered_susceptibility_to1.32977082
42MP0002272_abnormal_nervous_system1.31370162
43MP0005379_endocrine/exocrine_gland_phen1.25793964
44MP0001986_abnormal_taste_sensitivity1.24871294
45MP0005174_abnormal_tail_pigmentation1.24536851
46MP0001905_abnormal_dopamine_level1.24255096
47MP0006276_abnormal_autonomic_nervous1.24137639
48MP0005253_abnormal_eye_physiology1.21923554
49MP0001485_abnormal_pinna_reflex1.21321656
50MP0003011_delayed_dark_adaptation1.16348358
51MP0001970_abnormal_pain_threshold1.13359354
52MP0001919_abnormal_reproductive_system1.12928860
53MP0002095_abnormal_skin_pigmentation1.11632784
54MP0002733_abnormal_thermal_nociception1.07822947
55MP0005000_abnormal_immune_tolerance1.06183134
56MP0001873_stomach_inflammation1.05907080
57MP0001501_abnormal_sleep_pattern1.04598522
58MP0001790_abnormal_immune_system1.03882659
59MP0005387_immune_system_phenotype1.03882659
60MP0002723_abnormal_immune_serum1.03543680
61MP0009745_abnormal_behavioral_response1.03121088
62MP0006036_abnormal_mitochondrial_physio1.02795522
63MP0005360_urolithiasis1.01094638
64MP0002234_abnormal_pharynx_morphology0.98378989
65MP0000685_abnormal_immune_system0.97864302
66MP0003195_calcinosis0.96472934
67MP0002452_abnormal_antigen_presenting0.94111422
68MP0002938_white_spotting0.93008976
69MP0002006_tumorigenesis0.91099380
70MP0004742_abnormal_vestibular_system0.90886436
71MP0005394_taste/olfaction_phenotype0.88441047
72MP0005499_abnormal_olfactory_system0.88441047
73MP0001486_abnormal_startle_reflex0.88198455
74MP0000230_abnormal_systemic_arterial0.87882457
75MP0005636_abnormal_mineral_homeostasis0.87291865
76MP0003718_maternal_effect0.86576442
77MP0002166_altered_tumor_susceptibility0.86154379
78MP0002420_abnormal_adaptive_immunity0.85233273
79MP0001529_abnormal_vocalization0.84895798
80MP0005195_abnormal_posterior_eye0.83909138
81MP0001819_abnormal_immune_cell0.83825058
82MP0005464_abnormal_platelet_physiology0.83522078
83MP0009046_muscle_twitch0.83492459
84MP0001293_anophthalmia0.83487298
85MP0005410_abnormal_fertilization0.83245568
86MP0003880_abnormal_central_pattern0.81141533
87MP0003186_abnormal_redox_activity0.80899133
88MP0000631_abnormal_neuroendocrine_gland0.79004693
89MP0002653_abnormal_ependyma_morphology0.77948213
90MP0001440_abnormal_grooming_behavior0.77056128
91MP0008995_early_reproductive_senescence0.76290439
92MP0004043_abnormal_pH_regulation0.75760875
93MP0001663_abnormal_digestive_system0.75666820
94MP0002557_abnormal_social/conspecific_i0.75484247
95MP0005083_abnormal_biliary_tract0.74901375
96MP0003786_premature_aging0.73953786
97MP0003638_abnormal_response/metabolism_0.73916483
98MP0003136_yellow_coat_color0.73362842
99MP0001984_abnormal_olfaction0.73227400
100MP0005025_abnormal_response_to0.72914649

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.18723800
2Absent rod-and cone-mediated responses on ERG (HP:0007688)4.10478900
3Mitochondrial inheritance (HP:0001427)3.80965543
4Abnormal mitochondria in muscle tissue (HP:0008316)3.66514694
5Hepatocellular necrosis (HP:0001404)3.65816793
6Progressive macrocephaly (HP:0004481)3.57629338
7Congenital stationary night blindness (HP:0007642)3.56589393
8Increased CSF lactate (HP:0002490)3.50338104
9Acute encephalopathy (HP:0006846)3.45747199
10Pancreatic cysts (HP:0001737)3.45094790
11Abnormal rod and cone electroretinograms (HP:0008323)3.27944525
12Congenital, generalized hypertrichosis (HP:0004540)3.18907232
13Hepatic necrosis (HP:0002605)3.18769127
143-Methylglutaconic aciduria (HP:0003535)3.17024239
15Molar tooth sign on MRI (HP:0002419)3.14100846
16Abnormality of midbrain morphology (HP:0002418)3.14100846
17Abolished electroretinogram (ERG) (HP:0000550)3.05278084
18Pancreatic fibrosis (HP:0100732)2.94010715
19Reticulocytopenia (HP:0001896)2.91319265
20Optic disc pallor (HP:0000543)2.87282956
21Decreased central vision (HP:0007663)2.80491006
22Attenuation of retinal blood vessels (HP:0007843)2.80086994
23Type II lissencephaly (HP:0007260)2.76081554
24IgG deficiency (HP:0004315)2.73944544
25Decreased electroretinogram (ERG) amplitude (HP:0000654)2.71732465
26Elevated erythrocyte sedimentation rate (HP:0003565)2.63583508
27Abnormality of the prostate (HP:0008775)2.59866800
28Nephronophthisis (HP:0000090)2.59543651
29Type 2 muscle fiber atrophy (HP:0003554)2.58189403
30Abnormality of cells of the erythroid lineage (HP:0012130)2.56132238
31Cerebral edema (HP:0002181)2.54573741
32True hermaphroditism (HP:0010459)2.53983639
33Pendular nystagmus (HP:0012043)2.53684685
34Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.44345763
35Abnormality of alanine metabolism (HP:0010916)2.44345763
36Hyperalaninemia (HP:0003348)2.44345763
37Abnormality of the renal cortex (HP:0011035)2.43267262
38Abnormality of the renal medulla (HP:0100957)2.42436505
39Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.41035997
40Abnormality of the phalanges of the 5th finger (HP:0004213)2.34501778
41Increased hepatocellular lipid droplets (HP:0006565)2.33093870
42Medial flaring of the eyebrow (HP:0010747)2.31665207
43Constricted visual fields (HP:0001133)2.31313628
44Increased serum lactate (HP:0002151)2.31221507
45Lipid accumulation in hepatocytes (HP:0006561)2.27284588
46Methylmalonic acidemia (HP:0002912)2.26257031
47Hypoproteinemia (HP:0003075)2.25939376
48Aplasia/Hypoplasia of the fovea (HP:0008060)2.23405308
49Hypoplasia of the fovea (HP:0007750)2.23405308
50Increased corneal curvature (HP:0100692)2.23152667
51Keratoconus (HP:0000563)2.23152667
52Severe combined immunodeficiency (HP:0004430)2.21807661
53Abnormal number of erythroid precursors (HP:0012131)2.18429702
54Abnormal drinking behavior (HP:0030082)2.17148510
55Polydipsia (HP:0001959)2.17148510
56Macrocytic anemia (HP:0001972)2.15793220
57Muscle fiber atrophy (HP:0100295)2.15275988
58Abnormality of B cell number (HP:0010975)2.09226929
59Stomatitis (HP:0010280)2.09206726
60Aplastic anemia (HP:0001915)2.06350346
61Sclerocornea (HP:0000647)2.06191201
62Lactic acidosis (HP:0003128)2.04553866
63Absent thumb (HP:0009777)2.03349297
64Bile duct proliferation (HP:0001408)2.02020445
65Abnormal biliary tract physiology (HP:0012439)2.02020445
66Thyroiditis (HP:0100646)2.00964542
67Stenosis of the external auditory canal (HP:0000402)2.00840787
68Colon cancer (HP:0003003)2.00412309
69Polyuria (HP:0000103)1.97763541
70Optic nerve hypoplasia (HP:0000609)1.96598892
71Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.96011287
72Respiratory failure (HP:0002878)1.95873162
73Dynein arm defect of respiratory motile cilia (HP:0012255)1.93989066
74Absent/shortened dynein arms (HP:0200106)1.93989066
75Cystic liver disease (HP:0006706)1.93402836
76Tubular atrophy (HP:0000092)1.93075938
77Methylmalonic aciduria (HP:0012120)1.92401109
78Pallor (HP:0000980)1.90131822
79Increased IgM level (HP:0003496)1.89995135
80Renal Fanconi syndrome (HP:0001994)1.88553841
81Exertional dyspnea (HP:0002875)1.86431053
82Leukodystrophy (HP:0002415)1.86238325
83Hyperglycinemia (HP:0002154)1.85703873
84Aplasia/Hypoplasia of the spleen (HP:0010451)1.85142951
85Asplenia (HP:0001746)1.84838282
86Increased intramyocellular lipid droplets (HP:0012240)1.81126988
87Abnormality of the fovea (HP:0000493)1.80156627
88Prostate neoplasm (HP:0100787)1.79819392
89Stomach cancer (HP:0012126)1.79704560
90Lethargy (HP:0001254)1.77737390
91Delayed CNS myelination (HP:0002188)1.76510382
92Hypomagnesemia (HP:0002917)1.75530559
93Abnormality of the proximal phalanges of the hand (HP:0009834)1.75279181
94Supernumerary spleens (HP:0009799)1.74577106
95Aplasia/hypoplasia of the uterus (HP:0008684)1.74141069
96Pancytopenia (HP:0001876)1.73491958
97Abnormal hemoglobin (HP:0011902)1.69947520
98Abnormality of the phalanges of the 2nd finger (HP:0009541)1.69593193
99Hypoplasia of the uterus (HP:0000013)1.66716603
100Abnormal urine output (HP:0012590)1.65979922

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.79419696
2TAOK33.50250132
3MAP4K22.90637186
4ADRBK22.85776712
5ZAK2.85195219
6CDK192.60831119
7GRK12.57813759
8TLK12.49832768
9MUSK2.47128071
10FRK2.46919269
11NUAK12.43993724
12BMPR1B2.38488203
13TEC1.96200913
14STK161.94561165
15WNK41.89708128
16VRK21.84613291
17KDR1.83479076
18BCKDK1.73325116
19MAP3K121.73027463
20PINK11.67175249
21TIE11.66171981
22KIT1.60722049
23OXSR11.56869569
24ITK1.42797940
25TRPM71.28736471
26MAPK131.13314865
27SYK1.11948351
28WNK31.10224060
29PIK3CG1.08885120
30MAP4K11.07914426
31STK391.06245841
32MYLK1.03596322
33EIF2AK31.00317439
34PIM20.99659560
35PIK3CA0.99113976
36DYRK20.98910438
37GRK60.96479694
38FLT30.95894578
39PHKG10.94532534
40PHKG20.94532534
41BMPR20.94372159
42IKBKB0.93603036
43VRK10.93005901
44EIF2AK10.91023234
45PRKCQ0.90988965
46INSRR0.90724985
47ADRBK10.90530029
48GRK70.88801905
49MST40.86915328
50FES0.84841832
51CSF1R0.83825842
52GRK50.82617329
53PLK20.82568716
54ERBB30.77903880
55BTK0.74848997
56LYN0.74233670
57MAPKAPK50.73847345
58PTK2B0.67646884
59LCK0.66493048
60IKBKE0.66132145
61CAMKK20.65270665
62PRKCG0.62668234
63ARAF0.62438318
64PASK0.61533196
65RPS6KA50.59951934
66MKNK10.59727454
67OBSCN0.59218781
68MAP3K40.57872430
69ILK0.57596634
70CSNK1G20.57236722
71EIF2AK20.56416263
72TESK20.55335673
73PRKACA0.54633718
74TNK20.53146730
75CSNK1G30.51146021
76DAPK30.50150832
77PRKCE0.49519664
78IGF1R0.49439748
79MATK0.48802521
80ACVR1B0.48568028
81MAP2K20.48548146
82CAMKK10.48099707
83PDK20.47954370
84PRKCA0.46559443
85CDK80.44346223
86PRKCI0.44104439
87CAMK10.43777727
88RPS6KB20.43592336
89DAPK10.43459006
90RPS6KA60.43050330
91MAP2K60.42019401
92TAF10.41558037
93PLK30.38532509
94PKN10.38321038
95PRKCD0.37623327
96PIM10.35735672
97CSNK1G10.35608922
98NME10.34860040
99NEK10.34150940
100STK110.32995616

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.09392632
2Ribosome_Homo sapiens_hsa030103.38153557
3Oxidative phosphorylation_Homo sapiens_hsa001903.34502336
4Allograft rejection_Homo sapiens_hsa053303.31000204
5Autoimmune thyroid disease_Homo sapiens_hsa053203.06415818
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.97721621
7Graft-versus-host disease_Homo sapiens_hsa053322.92140422
8Parkinsons disease_Homo sapiens_hsa050122.74178569
9Proteasome_Homo sapiens_hsa030502.62062814
10Type I diabetes mellitus_Homo sapiens_hsa049402.57613708
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.09203954
12Caffeine metabolism_Homo sapiens_hsa002321.96281926
13Linoleic acid metabolism_Homo sapiens_hsa005911.90862185
14Primary immunodeficiency_Homo sapiens_hsa053401.87268388
15Alzheimers disease_Homo sapiens_hsa050101.82939260
16Protein export_Homo sapiens_hsa030601.82837988
17Phototransduction_Homo sapiens_hsa047441.79842076
18Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.76064268
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.75071870
20Cardiac muscle contraction_Homo sapiens_hsa042601.69772066
21Huntingtons disease_Homo sapiens_hsa050161.64930502
22Antigen processing and presentation_Homo sapiens_hsa046121.62557834
23Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.62463404
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.62435536
25RNA polymerase_Homo sapiens_hsa030201.47139860
26Rheumatoid arthritis_Homo sapiens_hsa053231.43760960
27Nitrogen metabolism_Homo sapiens_hsa009101.40347610
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39655522
29Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.39025285
30Homologous recombination_Homo sapiens_hsa034401.31439430
31Hematopoietic cell lineage_Homo sapiens_hsa046401.21977003
32One carbon pool by folate_Homo sapiens_hsa006701.20808660
33Staphylococcus aureus infection_Homo sapiens_hsa051501.20670289
34Arachidonic acid metabolism_Homo sapiens_hsa005901.19750734
35RNA degradation_Homo sapiens_hsa030181.18581114
36Tryptophan metabolism_Homo sapiens_hsa003801.14859244
37Butanoate metabolism_Homo sapiens_hsa006501.05898680
38Viral myocarditis_Homo sapiens_hsa054161.05225430
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.03696782
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02568753
41Systemic lupus erythematosus_Homo sapiens_hsa053220.98812632
42Olfactory transduction_Homo sapiens_hsa047400.93587347
43Peroxisome_Homo sapiens_hsa041460.92581624
44Chemical carcinogenesis_Homo sapiens_hsa052040.92199374
45Ether lipid metabolism_Homo sapiens_hsa005650.90287426
46Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88808931
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82626972
48Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.79672918
49Nicotine addiction_Homo sapiens_hsa050330.78739961
50Propanoate metabolism_Homo sapiens_hsa006400.77235269
51Retinol metabolism_Homo sapiens_hsa008300.77066740
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.76133883
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75282965
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.75000283
55Fanconi anemia pathway_Homo sapiens_hsa034600.71948812
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.71713246
57Fat digestion and absorption_Homo sapiens_hsa049750.70874458
58Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70806979
59Sulfur metabolism_Homo sapiens_hsa009200.66357273
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.66190795
61Basal transcription factors_Homo sapiens_hsa030220.64861223
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64389123
63Purine metabolism_Homo sapiens_hsa002300.62382406
64Leishmaniasis_Homo sapiens_hsa051400.61975972
65Salivary secretion_Homo sapiens_hsa049700.61326246
66Pyrimidine metabolism_Homo sapiens_hsa002400.61005420
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.59462429
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56601760
69Morphine addiction_Homo sapiens_hsa050320.54921299
70beta-Alanine metabolism_Homo sapiens_hsa004100.53442727
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53096553
72Collecting duct acid secretion_Homo sapiens_hsa049660.51991095
73Nucleotide excision repair_Homo sapiens_hsa034200.50411265
74Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50271529
75Metabolic pathways_Homo sapiens_hsa011000.49191108
76Drug metabolism - other enzymes_Homo sapiens_hsa009830.46112524
77Vitamin digestion and absorption_Homo sapiens_hsa049770.46098901
78Serotonergic synapse_Homo sapiens_hsa047260.43300065
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39818687
80Mismatch repair_Homo sapiens_hsa034300.39805814
81Regulation of autophagy_Homo sapiens_hsa041400.39497227
82Fatty acid degradation_Homo sapiens_hsa000710.39124689
83NOD-like receptor signaling pathway_Homo sapiens_hsa046210.36340788
84Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.34438366
85SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34323190
86Taste transduction_Homo sapiens_hsa047420.31354931
87Glycerolipid metabolism_Homo sapiens_hsa005610.30974074
88Mineral absorption_Homo sapiens_hsa049780.30646437
89Base excision repair_Homo sapiens_hsa034100.30336479
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30258706
91Ovarian steroidogenesis_Homo sapiens_hsa049130.30234039
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.29780483
93Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.28740462
94Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.27837929
95Circadian entrainment_Homo sapiens_hsa047130.27755512
96Herpes simplex infection_Homo sapiens_hsa051680.27690450
97African trypanosomiasis_Homo sapiens_hsa051430.24442303
98Spliceosome_Homo sapiens_hsa030400.22713904
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.22646638
100RNA transport_Homo sapiens_hsa030130.22457547

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »