

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.72861962 |
| 2 | DNA deamination (GO:0045006) | 5.07229576 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.79873078 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.79873078 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.42904527 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.27992743 |
| 7 | behavioral response to nicotine (GO:0035095) | 4.00347415 |
| 8 | viral transcription (GO:0019083) | 3.99756084 |
| 9 | protein neddylation (GO:0045116) | 3.88821240 |
| 10 | translational termination (GO:0006415) | 3.82991449 |
| 11 | kynurenine metabolic process (GO:0070189) | 3.79307244 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 3.77625355 |
| 13 | respiratory electron transport chain (GO:0022904) | 3.74429262 |
| 14 | electron transport chain (GO:0022900) | 3.73260704 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 3.70958134 |
| 16 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.66150480 |
| 17 | tryptophan catabolic process (GO:0006569) | 3.50497344 |
| 18 | indole-containing compound catabolic process (GO:0042436) | 3.50497344 |
| 19 | indolalkylamine catabolic process (GO:0046218) | 3.50497344 |
| 20 | translational elongation (GO:0006414) | 3.48202724 |
| 21 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.48047121 |
| 22 | protein complex biogenesis (GO:0070271) | 3.43057361 |
| 23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.42959736 |
| 24 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.42959736 |
| 25 | NADH dehydrogenase complex assembly (GO:0010257) | 3.42959736 |
| 26 | cotranslational protein targeting to membrane (GO:0006613) | 3.41658880 |
| 27 | protein targeting to ER (GO:0045047) | 3.40094892 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35305600 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35305600 |
| 30 | negative regulation of heart rate (GO:0010459) | 3.30227597 |
| 31 | chaperone-mediated protein transport (GO:0072321) | 3.30123277 |
| 32 | protein localization to endoplasmic reticulum (GO:0070972) | 3.27927615 |
| 33 | amine catabolic process (GO:0009310) | 3.27283288 |
| 34 | cellular biogenic amine catabolic process (GO:0042402) | 3.27283288 |
| 35 | cytidine metabolic process (GO:0046087) | 3.25326968 |
| 36 | cytidine catabolic process (GO:0006216) | 3.25326968 |
| 37 | cytidine deamination (GO:0009972) | 3.25326968 |
| 38 | indolalkylamine metabolic process (GO:0006586) | 3.23393619 |
| 39 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.22125943 |
| 40 | platelet dense granule organization (GO:0060155) | 3.21259859 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.12524540 |
| 42 | tryptophan metabolic process (GO:0006568) | 3.07920383 |
| 43 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.07436157 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.05868824 |
| 45 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.99967590 |
| 46 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.96672338 |
| 47 | cellular ketone body metabolic process (GO:0046950) | 2.96367593 |
| 48 | positive regulation of prostaglandin secretion (GO:0032308) | 2.95585812 |
| 49 | ribosomal small subunit biogenesis (GO:0042274) | 2.94135313 |
| 50 | GPI anchor metabolic process (GO:0006505) | 2.89825526 |
| 51 | negative regulation of mast cell activation (GO:0033004) | 2.89792038 |
| 52 | cornea development in camera-type eye (GO:0061303) | 2.88687185 |
| 53 | base-excision repair, AP site formation (GO:0006285) | 2.85961164 |
| 54 | negative regulation of telomere maintenance (GO:0032205) | 2.84208198 |
| 55 | viral life cycle (GO:0019058) | 2.83698050 |
| 56 | hydrogen ion transmembrane transport (GO:1902600) | 2.83374684 |
| 57 | parturition (GO:0007567) | 2.81113287 |
| 58 | proton transport (GO:0015992) | 2.79302160 |
| 59 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.77383994 |
| 60 | L-fucose metabolic process (GO:0042354) | 2.74662064 |
| 61 | L-fucose catabolic process (GO:0042355) | 2.74662064 |
| 62 | fucose catabolic process (GO:0019317) | 2.74662064 |
| 63 | hydrogen transport (GO:0006818) | 2.74446662 |
| 64 | cellular protein complex disassembly (GO:0043624) | 2.73959302 |
| 65 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.73617941 |
| 66 | piRNA metabolic process (GO:0034587) | 2.70533957 |
| 67 | ketone body metabolic process (GO:1902224) | 2.68375652 |
| 68 | ATP biosynthetic process (GO:0006754) | 2.66822847 |
| 69 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.66425462 |
| 70 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.64667159 |
| 71 | protein-cofactor linkage (GO:0018065) | 2.64264693 |
| 72 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.64238284 |
| 73 | positive regulation of defense response to virus by host (GO:0002230) | 2.64184376 |
| 74 | translation (GO:0006412) | 2.61776918 |
| 75 | positive regulation of fatty acid transport (GO:2000193) | 2.60003148 |
| 76 | mannosylation (GO:0097502) | 2.59365480 |
| 77 | dopamine transport (GO:0015872) | 2.59164981 |
| 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.57956252 |
| 79 | GPI anchor biosynthetic process (GO:0006506) | 2.57614715 |
| 80 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.56531328 |
| 81 | translational initiation (GO:0006413) | 2.55905700 |
| 82 | respiratory chain complex IV assembly (GO:0008535) | 2.55879809 |
| 83 | behavioral response to ethanol (GO:0048149) | 2.55777426 |
| 84 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.55602671 |
| 85 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.55456134 |
| 86 | response to pheromone (GO:0019236) | 2.53007242 |
| 87 | rRNA catabolic process (GO:0016075) | 2.47597799 |
| 88 | ubiquinone biosynthetic process (GO:0006744) | 2.47215229 |
| 89 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.46519690 |
| 90 | regulation of thymocyte apoptotic process (GO:0070243) | 2.46181613 |
| 91 | endoderm formation (GO:0001706) | 2.46120353 |
| 92 | aldehyde catabolic process (GO:0046185) | 2.45354449 |
| 93 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.40761787 |
| 94 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.40753678 |
| 95 | mast cell activation (GO:0045576) | 2.40346190 |
| 96 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.35766245 |
| 97 | cytochrome complex assembly (GO:0017004) | 2.35198624 |
| 98 | axoneme assembly (GO:0035082) | 2.34334761 |
| 99 | photoreceptor cell development (GO:0042461) | 2.32381663 |
| 100 | regulation of cilium movement (GO:0003352) | 2.32140375 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.64302874 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.10128960 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.99379719 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.72097690 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.64649623 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.45233641 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.43266255 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.38315343 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.31272747 |
| 10 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.22803104 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.19459133 |
| 12 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.14764030 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.05800312 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.00937386 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.96441330 |
| 16 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.93489003 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.89692647 |
| 18 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.75569172 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.74840696 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.72942856 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68456149 |
| 22 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.64384504 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.59611939 |
| 24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.58873028 |
| 25 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.57893496 |
| 26 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.56256411 |
| 27 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.56256411 |
| 28 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55046317 |
| 29 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.52210625 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51778414 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.51335660 |
| 32 | AR_20517297_ChIP-Seq_VCAP_Human | 1.50511485 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50005810 |
| 34 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.49788392 |
| 35 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45192117 |
| 36 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.44867677 |
| 37 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.42679010 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42415405 |
| 39 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.41671281 |
| 40 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.36357405 |
| 41 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.35251641 |
| 42 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.35163993 |
| 43 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.34921923 |
| 44 | GATA3_26560356_Chip-Seq_TH2_Human | 1.33659958 |
| 45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.32548386 |
| 46 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.32458844 |
| 47 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.31442970 |
| 48 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.30975973 |
| 49 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.30975973 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30714504 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.30457037 |
| 52 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.30069530 |
| 53 | NCOR_22424771_ChIP-Seq_293T_Human | 1.28046919 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27705365 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27705365 |
| 56 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.26333627 |
| 57 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.25174173 |
| 58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.24246184 |
| 59 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.23295989 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22772175 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.21764428 |
| 62 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.20308116 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.19140808 |
| 64 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18500164 |
| 65 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.17360108 |
| 66 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.14593455 |
| 67 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14550344 |
| 68 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.14295150 |
| 69 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.14099102 |
| 70 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.13623574 |
| 71 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13285680 |
| 72 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.13183920 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.12658754 |
| 74 | ERA_21632823_ChIP-Seq_H3396_Human | 1.09340385 |
| 75 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.05388953 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04768832 |
| 77 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04199413 |
| 78 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03936690 |
| 79 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03900324 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.03460446 |
| 81 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03268609 |
| 82 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.02216398 |
| 83 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.02157571 |
| 84 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.01941338 |
| 85 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01370045 |
| 86 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.00393963 |
| 87 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00009994 |
| 88 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98618279 |
| 89 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98015848 |
| 90 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.95146318 |
| 91 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.95008992 |
| 92 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.93883276 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.93836819 |
| 94 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93371699 |
| 95 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.91792804 |
| 96 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.91655611 |
| 97 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.90909932 |
| 98 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.90545574 |
| 99 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90355976 |
| 100 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.89709278 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.95577357 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.74036276 |
| 3 | MP0005671_abnormal_response_to | 2.83958912 |
| 4 | MP0002138_abnormal_hepatobiliary_system | 2.61179116 |
| 5 | MP0003787_abnormal_imprinting | 2.43642295 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.40223358 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.38256238 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.27101178 |
| 9 | MP0005645_abnormal_hypothalamus_physiol | 2.26726616 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.22835477 |
| 11 | MP0008872_abnormal_physiological_respon | 2.20630915 |
| 12 | MP0002163_abnormal_gland_morphology | 2.06090763 |
| 13 | MP0005075_abnormal_melanosome_morpholog | 2.04362620 |
| 14 | MP0003646_muscle_fatigue | 1.98640151 |
| 15 | MP0005646_abnormal_pituitary_gland | 1.97630462 |
| 16 | MP0001968_abnormal_touch/_nociception | 1.93560054 |
| 17 | MP0002736_abnormal_nociception_after | 1.87559907 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 1.86213983 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 1.85420893 |
| 20 | MP0002102_abnormal_ear_morphology | 1.84091632 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.82410809 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.81582010 |
| 23 | MP0004142_abnormal_muscle_tone | 1.79555228 |
| 24 | MP0004885_abnormal_endolymph | 1.72222345 |
| 25 | MP0004147_increased_porphyrin_level | 1.69114341 |
| 26 | MP0002876_abnormal_thyroid_physiology | 1.61811371 |
| 27 | MP0005085_abnormal_gallbladder_physiolo | 1.58828056 |
| 28 | MP0005377_hearing/vestibular/ear_phenot | 1.58662923 |
| 29 | MP0003878_abnormal_ear_physiology | 1.58662923 |
| 30 | MP0003252_abnormal_bile_duct | 1.57495855 |
| 31 | MP0002837_dystrophic_cardiac_calcinosis | 1.55925250 |
| 32 | MP0003724_increased_susceptibility_to | 1.52273035 |
| 33 | MP0002638_abnormal_pupillary_reflex | 1.51882688 |
| 34 | MP0003806_abnormal_nucleotide_metabolis | 1.48523277 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.48337965 |
| 36 | MP0008789_abnormal_olfactory_epithelium | 1.46986943 |
| 37 | MP0009764_decreased_sensitivity_to | 1.42004422 |
| 38 | MP0005389_reproductive_system_phenotype | 1.41544539 |
| 39 | MP0002160_abnormal_reproductive_system | 1.35157876 |
| 40 | MP0001800_abnormal_humoral_immune | 1.34348566 |
| 41 | MP0009785_altered_susceptibility_to | 1.32977082 |
| 42 | MP0002272_abnormal_nervous_system | 1.31370162 |
| 43 | MP0005379_endocrine/exocrine_gland_phen | 1.25793964 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.24871294 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.24536851 |
| 46 | MP0001905_abnormal_dopamine_level | 1.24255096 |
| 47 | MP0006276_abnormal_autonomic_nervous | 1.24137639 |
| 48 | MP0005253_abnormal_eye_physiology | 1.21923554 |
| 49 | MP0001485_abnormal_pinna_reflex | 1.21321656 |
| 50 | MP0003011_delayed_dark_adaptation | 1.16348358 |
| 51 | MP0001970_abnormal_pain_threshold | 1.13359354 |
| 52 | MP0001919_abnormal_reproductive_system | 1.12928860 |
| 53 | MP0002095_abnormal_skin_pigmentation | 1.11632784 |
| 54 | MP0002733_abnormal_thermal_nociception | 1.07822947 |
| 55 | MP0005000_abnormal_immune_tolerance | 1.06183134 |
| 56 | MP0001873_stomach_inflammation | 1.05907080 |
| 57 | MP0001501_abnormal_sleep_pattern | 1.04598522 |
| 58 | MP0001790_abnormal_immune_system | 1.03882659 |
| 59 | MP0005387_immune_system_phenotype | 1.03882659 |
| 60 | MP0002723_abnormal_immune_serum | 1.03543680 |
| 61 | MP0009745_abnormal_behavioral_response | 1.03121088 |
| 62 | MP0006036_abnormal_mitochondrial_physio | 1.02795522 |
| 63 | MP0005360_urolithiasis | 1.01094638 |
| 64 | MP0002234_abnormal_pharynx_morphology | 0.98378989 |
| 65 | MP0000685_abnormal_immune_system | 0.97864302 |
| 66 | MP0003195_calcinosis | 0.96472934 |
| 67 | MP0002452_abnormal_antigen_presenting | 0.94111422 |
| 68 | MP0002938_white_spotting | 0.93008976 |
| 69 | MP0002006_tumorigenesis | 0.91099380 |
| 70 | MP0004742_abnormal_vestibular_system | 0.90886436 |
| 71 | MP0005394_taste/olfaction_phenotype | 0.88441047 |
| 72 | MP0005499_abnormal_olfactory_system | 0.88441047 |
| 73 | MP0001486_abnormal_startle_reflex | 0.88198455 |
| 74 | MP0000230_abnormal_systemic_arterial | 0.87882457 |
| 75 | MP0005636_abnormal_mineral_homeostasis | 0.87291865 |
| 76 | MP0003718_maternal_effect | 0.86576442 |
| 77 | MP0002166_altered_tumor_susceptibility | 0.86154379 |
| 78 | MP0002420_abnormal_adaptive_immunity | 0.85233273 |
| 79 | MP0001529_abnormal_vocalization | 0.84895798 |
| 80 | MP0005195_abnormal_posterior_eye | 0.83909138 |
| 81 | MP0001819_abnormal_immune_cell | 0.83825058 |
| 82 | MP0005464_abnormal_platelet_physiology | 0.83522078 |
| 83 | MP0009046_muscle_twitch | 0.83492459 |
| 84 | MP0001293_anophthalmia | 0.83487298 |
| 85 | MP0005410_abnormal_fertilization | 0.83245568 |
| 86 | MP0003880_abnormal_central_pattern | 0.81141533 |
| 87 | MP0003186_abnormal_redox_activity | 0.80899133 |
| 88 | MP0000631_abnormal_neuroendocrine_gland | 0.79004693 |
| 89 | MP0002653_abnormal_ependyma_morphology | 0.77948213 |
| 90 | MP0001440_abnormal_grooming_behavior | 0.77056128 |
| 91 | MP0008995_early_reproductive_senescence | 0.76290439 |
| 92 | MP0004043_abnormal_pH_regulation | 0.75760875 |
| 93 | MP0001663_abnormal_digestive_system | 0.75666820 |
| 94 | MP0002557_abnormal_social/conspecific_i | 0.75484247 |
| 95 | MP0005083_abnormal_biliary_tract | 0.74901375 |
| 96 | MP0003786_premature_aging | 0.73953786 |
| 97 | MP0003638_abnormal_response/metabolism_ | 0.73916483 |
| 98 | MP0003136_yellow_coat_color | 0.73362842 |
| 99 | MP0001984_abnormal_olfaction | 0.73227400 |
| 100 | MP0005025_abnormal_response_to | 0.72914649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.18723800 |
| 2 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.10478900 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.80965543 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.66514694 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.65816793 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.57629338 |
| 7 | Congenital stationary night blindness (HP:0007642) | 3.56589393 |
| 8 | Increased CSF lactate (HP:0002490) | 3.50338104 |
| 9 | Acute encephalopathy (HP:0006846) | 3.45747199 |
| 10 | Pancreatic cysts (HP:0001737) | 3.45094790 |
| 11 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.27944525 |
| 12 | Congenital, generalized hypertrichosis (HP:0004540) | 3.18907232 |
| 13 | Hepatic necrosis (HP:0002605) | 3.18769127 |
| 14 | 3-Methylglutaconic aciduria (HP:0003535) | 3.17024239 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 3.14100846 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 3.14100846 |
| 17 | Abolished electroretinogram (ERG) (HP:0000550) | 3.05278084 |
| 18 | Pancreatic fibrosis (HP:0100732) | 2.94010715 |
| 19 | Reticulocytopenia (HP:0001896) | 2.91319265 |
| 20 | Optic disc pallor (HP:0000543) | 2.87282956 |
| 21 | Decreased central vision (HP:0007663) | 2.80491006 |
| 22 | Attenuation of retinal blood vessels (HP:0007843) | 2.80086994 |
| 23 | Type II lissencephaly (HP:0007260) | 2.76081554 |
| 24 | IgG deficiency (HP:0004315) | 2.73944544 |
| 25 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.71732465 |
| 26 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63583508 |
| 27 | Abnormality of the prostate (HP:0008775) | 2.59866800 |
| 28 | Nephronophthisis (HP:0000090) | 2.59543651 |
| 29 | Type 2 muscle fiber atrophy (HP:0003554) | 2.58189403 |
| 30 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.56132238 |
| 31 | Cerebral edema (HP:0002181) | 2.54573741 |
| 32 | True hermaphroditism (HP:0010459) | 2.53983639 |
| 33 | Pendular nystagmus (HP:0012043) | 2.53684685 |
| 34 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.44345763 |
| 35 | Abnormality of alanine metabolism (HP:0010916) | 2.44345763 |
| 36 | Hyperalaninemia (HP:0003348) | 2.44345763 |
| 37 | Abnormality of the renal cortex (HP:0011035) | 2.43267262 |
| 38 | Abnormality of the renal medulla (HP:0100957) | 2.42436505 |
| 39 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.41035997 |
| 40 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.34501778 |
| 41 | Increased hepatocellular lipid droplets (HP:0006565) | 2.33093870 |
| 42 | Medial flaring of the eyebrow (HP:0010747) | 2.31665207 |
| 43 | Constricted visual fields (HP:0001133) | 2.31313628 |
| 44 | Increased serum lactate (HP:0002151) | 2.31221507 |
| 45 | Lipid accumulation in hepatocytes (HP:0006561) | 2.27284588 |
| 46 | Methylmalonic acidemia (HP:0002912) | 2.26257031 |
| 47 | Hypoproteinemia (HP:0003075) | 2.25939376 |
| 48 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.23405308 |
| 49 | Hypoplasia of the fovea (HP:0007750) | 2.23405308 |
| 50 | Increased corneal curvature (HP:0100692) | 2.23152667 |
| 51 | Keratoconus (HP:0000563) | 2.23152667 |
| 52 | Severe combined immunodeficiency (HP:0004430) | 2.21807661 |
| 53 | Abnormal number of erythroid precursors (HP:0012131) | 2.18429702 |
| 54 | Abnormal drinking behavior (HP:0030082) | 2.17148510 |
| 55 | Polydipsia (HP:0001959) | 2.17148510 |
| 56 | Macrocytic anemia (HP:0001972) | 2.15793220 |
| 57 | Muscle fiber atrophy (HP:0100295) | 2.15275988 |
| 58 | Abnormality of B cell number (HP:0010975) | 2.09226929 |
| 59 | Stomatitis (HP:0010280) | 2.09206726 |
| 60 | Aplastic anemia (HP:0001915) | 2.06350346 |
| 61 | Sclerocornea (HP:0000647) | 2.06191201 |
| 62 | Lactic acidosis (HP:0003128) | 2.04553866 |
| 63 | Absent thumb (HP:0009777) | 2.03349297 |
| 64 | Bile duct proliferation (HP:0001408) | 2.02020445 |
| 65 | Abnormal biliary tract physiology (HP:0012439) | 2.02020445 |
| 66 | Thyroiditis (HP:0100646) | 2.00964542 |
| 67 | Stenosis of the external auditory canal (HP:0000402) | 2.00840787 |
| 68 | Colon cancer (HP:0003003) | 2.00412309 |
| 69 | Polyuria (HP:0000103) | 1.97763541 |
| 70 | Optic nerve hypoplasia (HP:0000609) | 1.96598892 |
| 71 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.96011287 |
| 72 | Respiratory failure (HP:0002878) | 1.95873162 |
| 73 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.93989066 |
| 74 | Absent/shortened dynein arms (HP:0200106) | 1.93989066 |
| 75 | Cystic liver disease (HP:0006706) | 1.93402836 |
| 76 | Tubular atrophy (HP:0000092) | 1.93075938 |
| 77 | Methylmalonic aciduria (HP:0012120) | 1.92401109 |
| 78 | Pallor (HP:0000980) | 1.90131822 |
| 79 | Increased IgM level (HP:0003496) | 1.89995135 |
| 80 | Renal Fanconi syndrome (HP:0001994) | 1.88553841 |
| 81 | Exertional dyspnea (HP:0002875) | 1.86431053 |
| 82 | Leukodystrophy (HP:0002415) | 1.86238325 |
| 83 | Hyperglycinemia (HP:0002154) | 1.85703873 |
| 84 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.85142951 |
| 85 | Asplenia (HP:0001746) | 1.84838282 |
| 86 | Increased intramyocellular lipid droplets (HP:0012240) | 1.81126988 |
| 87 | Abnormality of the fovea (HP:0000493) | 1.80156627 |
| 88 | Prostate neoplasm (HP:0100787) | 1.79819392 |
| 89 | Stomach cancer (HP:0012126) | 1.79704560 |
| 90 | Lethargy (HP:0001254) | 1.77737390 |
| 91 | Delayed CNS myelination (HP:0002188) | 1.76510382 |
| 92 | Hypomagnesemia (HP:0002917) | 1.75530559 |
| 93 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.75279181 |
| 94 | Supernumerary spleens (HP:0009799) | 1.74577106 |
| 95 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.74141069 |
| 96 | Pancytopenia (HP:0001876) | 1.73491958 |
| 97 | Abnormal hemoglobin (HP:0011902) | 1.69947520 |
| 98 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.69593193 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.66716603 |
| 100 | Abnormal urine output (HP:0012590) | 1.65979922 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.79419696 |
| 2 | TAOK3 | 3.50250132 |
| 3 | MAP4K2 | 2.90637186 |
| 4 | ADRBK2 | 2.85776712 |
| 5 | ZAK | 2.85195219 |
| 6 | CDK19 | 2.60831119 |
| 7 | GRK1 | 2.57813759 |
| 8 | TLK1 | 2.49832768 |
| 9 | MUSK | 2.47128071 |
| 10 | FRK | 2.46919269 |
| 11 | NUAK1 | 2.43993724 |
| 12 | BMPR1B | 2.38488203 |
| 13 | TEC | 1.96200913 |
| 14 | STK16 | 1.94561165 |
| 15 | WNK4 | 1.89708128 |
| 16 | VRK2 | 1.84613291 |
| 17 | KDR | 1.83479076 |
| 18 | BCKDK | 1.73325116 |
| 19 | MAP3K12 | 1.73027463 |
| 20 | PINK1 | 1.67175249 |
| 21 | TIE1 | 1.66171981 |
| 22 | KIT | 1.60722049 |
| 23 | OXSR1 | 1.56869569 |
| 24 | ITK | 1.42797940 |
| 25 | TRPM7 | 1.28736471 |
| 26 | MAPK13 | 1.13314865 |
| 27 | SYK | 1.11948351 |
| 28 | WNK3 | 1.10224060 |
| 29 | PIK3CG | 1.08885120 |
| 30 | MAP4K1 | 1.07914426 |
| 31 | STK39 | 1.06245841 |
| 32 | MYLK | 1.03596322 |
| 33 | EIF2AK3 | 1.00317439 |
| 34 | PIM2 | 0.99659560 |
| 35 | PIK3CA | 0.99113976 |
| 36 | DYRK2 | 0.98910438 |
| 37 | GRK6 | 0.96479694 |
| 38 | FLT3 | 0.95894578 |
| 39 | PHKG1 | 0.94532534 |
| 40 | PHKG2 | 0.94532534 |
| 41 | BMPR2 | 0.94372159 |
| 42 | IKBKB | 0.93603036 |
| 43 | VRK1 | 0.93005901 |
| 44 | EIF2AK1 | 0.91023234 |
| 45 | PRKCQ | 0.90988965 |
| 46 | INSRR | 0.90724985 |
| 47 | ADRBK1 | 0.90530029 |
| 48 | GRK7 | 0.88801905 |
| 49 | MST4 | 0.86915328 |
| 50 | FES | 0.84841832 |
| 51 | CSF1R | 0.83825842 |
| 52 | GRK5 | 0.82617329 |
| 53 | PLK2 | 0.82568716 |
| 54 | ERBB3 | 0.77903880 |
| 55 | BTK | 0.74848997 |
| 56 | LYN | 0.74233670 |
| 57 | MAPKAPK5 | 0.73847345 |
| 58 | PTK2B | 0.67646884 |
| 59 | LCK | 0.66493048 |
| 60 | IKBKE | 0.66132145 |
| 61 | CAMKK2 | 0.65270665 |
| 62 | PRKCG | 0.62668234 |
| 63 | ARAF | 0.62438318 |
| 64 | PASK | 0.61533196 |
| 65 | RPS6KA5 | 0.59951934 |
| 66 | MKNK1 | 0.59727454 |
| 67 | OBSCN | 0.59218781 |
| 68 | MAP3K4 | 0.57872430 |
| 69 | ILK | 0.57596634 |
| 70 | CSNK1G2 | 0.57236722 |
| 71 | EIF2AK2 | 0.56416263 |
| 72 | TESK2 | 0.55335673 |
| 73 | PRKACA | 0.54633718 |
| 74 | TNK2 | 0.53146730 |
| 75 | CSNK1G3 | 0.51146021 |
| 76 | DAPK3 | 0.50150832 |
| 77 | PRKCE | 0.49519664 |
| 78 | IGF1R | 0.49439748 |
| 79 | MATK | 0.48802521 |
| 80 | ACVR1B | 0.48568028 |
| 81 | MAP2K2 | 0.48548146 |
| 82 | CAMKK1 | 0.48099707 |
| 83 | PDK2 | 0.47954370 |
| 84 | PRKCA | 0.46559443 |
| 85 | CDK8 | 0.44346223 |
| 86 | PRKCI | 0.44104439 |
| 87 | CAMK1 | 0.43777727 |
| 88 | RPS6KB2 | 0.43592336 |
| 89 | DAPK1 | 0.43459006 |
| 90 | RPS6KA6 | 0.43050330 |
| 91 | MAP2K6 | 0.42019401 |
| 92 | TAF1 | 0.41558037 |
| 93 | PLK3 | 0.38532509 |
| 94 | PKN1 | 0.38321038 |
| 95 | PRKCD | 0.37623327 |
| 96 | PIM1 | 0.35735672 |
| 97 | CSNK1G1 | 0.35608922 |
| 98 | NME1 | 0.34860040 |
| 99 | NEK1 | 0.34150940 |
| 100 | STK11 | 0.32995616 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.09392632 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.38153557 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34502336 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.31000204 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.06415818 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.97721621 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.92140422 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.74178569 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.62062814 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.57613708 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.09203954 |
| 12 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.96281926 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.90862185 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.87268388 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.82939260 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.82837988 |
| 17 | Phototransduction_Homo sapiens_hsa04744 | 1.79842076 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.76064268 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.75071870 |
| 20 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.69772066 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.64930502 |
| 22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.62557834 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.62463404 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.62435536 |
| 25 | RNA polymerase_Homo sapiens_hsa03020 | 1.47139860 |
| 26 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.43760960 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.40347610 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.39655522 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.39025285 |
| 30 | Homologous recombination_Homo sapiens_hsa03440 | 1.31439430 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21977003 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.20808660 |
| 33 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.20670289 |
| 34 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.19750734 |
| 35 | RNA degradation_Homo sapiens_hsa03018 | 1.18581114 |
| 36 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.14859244 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.05898680 |
| 38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.05225430 |
| 39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03696782 |
| 40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.02568753 |
| 41 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.98812632 |
| 42 | Olfactory transduction_Homo sapiens_hsa04740 | 0.93587347 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.92581624 |
| 44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92199374 |
| 45 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.90287426 |
| 46 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88808931 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82626972 |
| 48 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.79672918 |
| 49 | Nicotine addiction_Homo sapiens_hsa05033 | 0.78739961 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.77235269 |
| 51 | Retinol metabolism_Homo sapiens_hsa00830 | 0.77066740 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.76133883 |
| 53 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.75282965 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.75000283 |
| 55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71948812 |
| 56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71713246 |
| 57 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70874458 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70806979 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.66357273 |
| 60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.66190795 |
| 61 | Basal transcription factors_Homo sapiens_hsa03022 | 0.64861223 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.64389123 |
| 63 | Purine metabolism_Homo sapiens_hsa00230 | 0.62382406 |
| 64 | Leishmaniasis_Homo sapiens_hsa05140 | 0.61975972 |
| 65 | Salivary secretion_Homo sapiens_hsa04970 | 0.61326246 |
| 66 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.61005420 |
| 67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.59462429 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56601760 |
| 69 | Morphine addiction_Homo sapiens_hsa05032 | 0.54921299 |
| 70 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.53442727 |
| 71 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.53096553 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51991095 |
| 73 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50411265 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.50271529 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49191108 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46112524 |
| 77 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.46098901 |
| 78 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43300065 |
| 79 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.39818687 |
| 80 | Mismatch repair_Homo sapiens_hsa03430 | 0.39805814 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.39497227 |
| 82 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39124689 |
| 83 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36340788 |
| 84 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34438366 |
| 85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34323190 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.31354931 |
| 87 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.30974074 |
| 88 | Mineral absorption_Homo sapiens_hsa04978 | 0.30646437 |
| 89 | Base excision repair_Homo sapiens_hsa03410 | 0.30336479 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.30258706 |
| 91 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30234039 |
| 92 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.29780483 |
| 93 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.28740462 |
| 94 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27837929 |
| 95 | Circadian entrainment_Homo sapiens_hsa04713 | 0.27755512 |
| 96 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.27690450 |
| 97 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.24442303 |
| 98 | Spliceosome_Homo sapiens_hsa03040 | 0.22713904 |
| 99 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.22646638 |
| 100 | RNA transport_Homo sapiens_hsa03013 | 0.22457547 |

