

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of prostaglandin secretion (GO:0032308) | 7.57619216 |
| 2 | viral transcription (GO:0019083) | 7.46275489 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 7.25290420 |
| 4 | translational termination (GO:0006415) | 7.18064598 |
| 5 | translational elongation (GO:0006414) | 6.28121649 |
| 6 | regulation of prostaglandin secretion (GO:0032306) | 6.18726620 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.11039748 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.99903287 |
| 9 | protein targeting to ER (GO:0045047) | 5.97028505 |
| 10 | ribosomal small subunit biogenesis (GO:0042274) | 5.76622669 |
| 11 | regulation of glucocorticoid secretion (GO:2000849) | 5.68108838 |
| 12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.67666405 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 5.61083572 |
| 14 | viral life cycle (GO:0019058) | 5.51249113 |
| 15 | DNA deamination (GO:0045006) | 5.47798777 |
| 16 | positive regulation of icosanoid secretion (GO:0032305) | 5.46522820 |
| 17 | positive regulation of fatty acid transport (GO:2000193) | 5.41381043 |
| 18 | cellular protein complex disassembly (GO:0043624) | 5.36048610 |
| 19 | protein neddylation (GO:0045116) | 5.21479025 |
| 20 | behavioral response to nicotine (GO:0035095) | 5.17234101 |
| 21 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.12940696 |
| 22 | maturation of SSU-rRNA (GO:0030490) | 5.00607250 |
| 23 | translational initiation (GO:0006413) | 4.71053195 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.57316430 |
| 25 | ATP synthesis coupled proton transport (GO:0015986) | 4.57316430 |
| 26 | regulation of corticosteroid hormone secretion (GO:2000846) | 4.53526260 |
| 27 | ribosomal large subunit biogenesis (GO:0042273) | 4.50145506 |
| 28 | protein complex disassembly (GO:0043241) | 4.49324588 |
| 29 | macromolecular complex disassembly (GO:0032984) | 4.23572327 |
| 30 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.19881574 |
| 31 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 4.15757478 |
| 32 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.15165110 |
| 33 | chaperone-mediated protein transport (GO:0072321) | 4.10326152 |
| 34 | protein targeting to membrane (GO:0006612) | 3.99604551 |
| 35 | regulation of icosanoid secretion (GO:0032303) | 3.94152872 |
| 36 | regulation of appetite (GO:0032098) | 3.90916027 |
| 37 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.87974967 |
| 38 | translation (GO:0006412) | 3.87757175 |
| 39 | nonmotile primary cilium assembly (GO:0035058) | 3.80136563 |
| 40 | GTP biosynthetic process (GO:0006183) | 3.68650050 |
| 41 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.66552565 |
| 42 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.66502977 |
| 43 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.66336429 |
| 44 | NADH dehydrogenase complex assembly (GO:0010257) | 3.63202413 |
| 45 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.63202413 |
| 46 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.63202413 |
| 47 | mRNA catabolic process (GO:0006402) | 3.46261887 |
| 48 | cellular component biogenesis (GO:0044085) | 3.44094467 |
| 49 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 3.42830534 |
| 50 | regulation of steroid hormone secretion (GO:2000831) | 3.35959612 |
| 51 | protein complex biogenesis (GO:0070271) | 3.33160705 |
| 52 | anterograde synaptic vesicle transport (GO:0048490) | 3.32806427 |
| 53 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.28452538 |
| 54 | ubiquinone biosynthetic process (GO:0006744) | 3.26365736 |
| 55 | metallo-sulfur cluster assembly (GO:0031163) | 3.25730123 |
| 56 | iron-sulfur cluster assembly (GO:0016226) | 3.25730123 |
| 57 | UTP biosynthetic process (GO:0006228) | 3.21830774 |
| 58 | base-excision repair, AP site formation (GO:0006285) | 3.18377775 |
| 59 | positive regulation of organic acid transport (GO:0032892) | 3.16231971 |
| 60 | RNA catabolic process (GO:0006401) | 3.13463622 |
| 61 | rRNA processing (GO:0006364) | 3.07209470 |
| 62 | regulation of cilium movement (GO:0003352) | 3.06839701 |
| 63 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.06016718 |
| 64 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.05147901 |
| 65 | termination of RNA polymerase III transcription (GO:0006386) | 3.05147901 |
| 66 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.04418187 |
| 67 | rRNA metabolic process (GO:0016072) | 3.02527069 |
| 68 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.02066959 |
| 69 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.01975906 |
| 70 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.01699837 |
| 71 | negative regulation of sterol transport (GO:0032372) | 3.01050754 |
| 72 | negative regulation of cholesterol transport (GO:0032375) | 3.01050754 |
| 73 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.99990910 |
| 74 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.99990910 |
| 75 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.98537894 |
| 76 | UTP metabolic process (GO:0046051) | 2.98211835 |
| 77 | electron transport chain (GO:0022900) | 2.95171210 |
| 78 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 2.93014830 |
| 79 | ubiquinone metabolic process (GO:0006743) | 2.92977017 |
| 80 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.86576273 |
| 81 | respiratory electron transport chain (GO:0022904) | 2.82695842 |
| 82 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.82550455 |
| 83 | positive regulation of defense response to virus by host (GO:0002230) | 2.81571161 |
| 84 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.80540338 |
| 85 | regulation of immunoglobulin secretion (GO:0051023) | 2.77011726 |
| 86 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.76533774 |
| 87 | ncRNA 3-end processing (GO:0043628) | 2.76477167 |
| 88 | protein-cofactor linkage (GO:0018065) | 2.75090350 |
| 89 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.70164475 |
| 90 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.70164475 |
| 91 | rRNA modification (GO:0000154) | 2.70070688 |
| 92 | ribosome biogenesis (GO:0042254) | 2.65419375 |
| 93 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 2.63412005 |
| 94 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.62557451 |
| 95 | tRNA processing (GO:0008033) | 2.62080721 |
| 96 | respiratory chain complex IV assembly (GO:0008535) | 2.61800828 |
| 97 | establishment of protein localization to membrane (GO:0090150) | 2.61370334 |
| 98 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.60586088 |
| 99 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.58923884 |
| 100 | positive regulation of cell fate commitment (GO:0010455) | 2.58912223 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.03462871 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.02734924 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.90991584 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.63547578 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.50763921 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.15290582 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.96792906 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95867046 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.89546439 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.89243430 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.87847254 |
| 12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.61071702 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.48706623 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.45038335 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.29483205 |
| 16 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.24521058 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.20263634 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.15545631 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.01100365 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.95922921 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.87186415 |
| 22 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.80045063 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.78869360 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.75122995 |
| 25 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.74152083 |
| 26 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72218123 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.66277822 |
| 28 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.65763120 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.63771034 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.63629881 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.62961202 |
| 32 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.58701679 |
| 33 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.47743364 |
| 34 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.47367700 |
| 35 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.46792461 |
| 36 | VDR_22108803_ChIP-Seq_LS180_Human | 1.46597492 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.43805695 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.40455843 |
| 39 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.37780267 |
| 40 | NCOR_22424771_ChIP-Seq_293T_Human | 1.36819356 |
| 41 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.34792468 |
| 42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.34583198 |
| 43 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.32034584 |
| 44 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.31983111 |
| 45 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.30938068 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30692195 |
| 47 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.27357345 |
| 48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.26792356 |
| 49 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.24822465 |
| 50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.22097144 |
| 51 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.21565673 |
| 52 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.20857141 |
| 53 | ERA_21632823_ChIP-Seq_H3396_Human | 1.18883941 |
| 54 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17953624 |
| 55 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.16458335 |
| 56 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16082883 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.16029259 |
| 58 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.13353492 |
| 59 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.13353492 |
| 60 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.12859264 |
| 61 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09756101 |
| 62 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.08641708 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.08383016 |
| 64 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05562907 |
| 65 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.04798097 |
| 66 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04730639 |
| 67 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04012417 |
| 68 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03839770 |
| 69 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.02624935 |
| 70 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.01830625 |
| 71 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.01449725 |
| 72 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.01444390 |
| 73 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.99401385 |
| 74 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98477596 |
| 75 | GATA3_26560356_Chip-Seq_TH2_Human | 0.97786395 |
| 76 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.97413073 |
| 77 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.97244500 |
| 78 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.96524297 |
| 79 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.96307567 |
| 80 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.95913016 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94962985 |
| 82 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94962985 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 0.94760183 |
| 84 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.93792646 |
| 85 | SA1_27219007_Chip-Seq_Bcells_Human | 0.93348806 |
| 86 | P300_27268052_Chip-Seq_Bcells_Human | 0.91233377 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.90985973 |
| 88 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.90610745 |
| 89 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.90506358 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89879857 |
| 91 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89862395 |
| 92 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89684353 |
| 93 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.89450669 |
| 94 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89448708 |
| 95 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.88414693 |
| 96 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.88122553 |
| 97 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.86994181 |
| 98 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.84235669 |
| 99 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.83937361 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.83414977 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 5.30296105 |
| 2 | MP0009379_abnormal_foot_pigmentation | 5.14150092 |
| 3 | MP0006292_abnormal_olfactory_placode | 4.30173255 |
| 4 | MP0001968_abnormal_touch/_nociception | 3.46493052 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.73742730 |
| 6 | MP0002909_abnormal_adrenal_gland | 2.59754610 |
| 7 | MP0003787_abnormal_imprinting | 2.56867426 |
| 8 | MP0004147_increased_porphyrin_level | 2.19575947 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.08924052 |
| 10 | MP0005671_abnormal_response_to | 2.08869543 |
| 11 | MP0001905_abnormal_dopamine_level | 2.00770381 |
| 12 | MP0005646_abnormal_pituitary_gland | 2.00306672 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 1.99499640 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 1.95581671 |
| 15 | MP0002638_abnormal_pupillary_reflex | 1.92241226 |
| 16 | MP0002163_abnormal_gland_morphology | 1.92134861 |
| 17 | MP0006276_abnormal_autonomic_nervous | 1.91594078 |
| 18 | MP0004142_abnormal_muscle_tone | 1.80942742 |
| 19 | MP0003646_muscle_fatigue | 1.76320729 |
| 20 | MP0003879_abnormal_hair_cell | 1.74434936 |
| 21 | MP0002653_abnormal_ependyma_morphology | 1.64091591 |
| 22 | MP0002736_abnormal_nociception_after | 1.59581831 |
| 23 | MP0004885_abnormal_endolymph | 1.58654144 |
| 24 | MP0010386_abnormal_urinary_bladder | 1.58631970 |
| 25 | MP0003878_abnormal_ear_physiology | 1.58599584 |
| 26 | MP0005377_hearing/vestibular/ear_phenot | 1.58599584 |
| 27 | MP0005083_abnormal_biliary_tract | 1.58459834 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.42200276 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.36440894 |
| 30 | MP0008872_abnormal_physiological_respon | 1.36265955 |
| 31 | MP0000049_abnormal_middle_ear | 1.34706668 |
| 32 | MP0008058_abnormal_DNA_repair | 1.32680151 |
| 33 | MP0005394_taste/olfaction_phenotype | 1.32442091 |
| 34 | MP0005499_abnormal_olfactory_system | 1.32442091 |
| 35 | MP0003638_abnormal_response/metabolism_ | 1.29165401 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.26771524 |
| 37 | MP0002277_abnormal_respiratory_mucosa | 1.21583610 |
| 38 | MP0003786_premature_aging | 1.20217363 |
| 39 | MP0005084_abnormal_gallbladder_morpholo | 1.18887982 |
| 40 | MP0001800_abnormal_humoral_immune | 1.18507588 |
| 41 | MP0001835_abnormal_antigen_presentation | 1.17808468 |
| 42 | MP0002138_abnormal_hepatobiliary_system | 1.17161692 |
| 43 | MP0002837_dystrophic_cardiac_calcinosis | 1.15187066 |
| 44 | MP0002557_abnormal_social/conspecific_i | 1.11832976 |
| 45 | MP0009745_abnormal_behavioral_response | 1.11342536 |
| 46 | MP0002160_abnormal_reproductive_system | 1.11121408 |
| 47 | MP0005389_reproductive_system_phenotype | 1.10896063 |
| 48 | MP0004484_altered_response_of | 1.09466338 |
| 49 | MP0002938_white_spotting | 1.09257123 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.09250890 |
| 51 | MP0001986_abnormal_taste_sensitivity | 1.06534170 |
| 52 | MP0003186_abnormal_redox_activity | 1.06091437 |
| 53 | MP0002148_abnormal_hypersensitivity_rea | 1.04491382 |
| 54 | MP0003122_maternal_imprinting | 1.02517618 |
| 55 | MP0005386_behavior/neurological_phenoty | 1.01911561 |
| 56 | MP0004924_abnormal_behavior | 1.01911561 |
| 57 | MP0005645_abnormal_hypothalamus_physiol | 1.01289528 |
| 58 | MP0005085_abnormal_gallbladder_physiolo | 0.98625609 |
| 59 | MP0000230_abnormal_systemic_arterial | 0.97851227 |
| 60 | MP0000465_gastrointestinal_hemorrhage | 0.97233182 |
| 61 | MP0001440_abnormal_grooming_behavior | 0.97214024 |
| 62 | MP0003011_delayed_dark_adaptation | 0.97071142 |
| 63 | MP0001963_abnormal_hearing_physiology | 0.96847445 |
| 64 | MP0003718_maternal_effect | 0.96481952 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 0.96366790 |
| 66 | MP0001293_anophthalmia | 0.96053382 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 0.95982703 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.95474498 |
| 69 | MP0001919_abnormal_reproductive_system | 0.94764069 |
| 70 | MP0005448_abnormal_energy_balance | 0.94331890 |
| 71 | MP0008775_abnormal_heart_ventricle | 0.93483616 |
| 72 | MP0003121_genomic_imprinting | 0.93137026 |
| 73 | MP0001765_abnormal_ion_homeostasis | 0.92909376 |
| 74 | MP0000371_diluted_coat_color | 0.91907870 |
| 75 | MP0000026_abnormal_inner_ear | 0.91778537 |
| 76 | MP0002723_abnormal_immune_serum | 0.91590457 |
| 77 | MP0002272_abnormal_nervous_system | 0.89261207 |
| 78 | MP0000343_altered_response_to | 0.89129420 |
| 79 | MP0000639_abnormal_adrenal_gland | 0.88464512 |
| 80 | MP0001873_stomach_inflammation | 0.86623330 |
| 81 | MP0005253_abnormal_eye_physiology | 0.85585923 |
| 82 | MP0001790_abnormal_immune_system | 0.83523424 |
| 83 | MP0005387_immune_system_phenotype | 0.83523424 |
| 84 | MP0009053_abnormal_anal_canal | 0.78187442 |
| 85 | MP0002095_abnormal_skin_pigmentation | 0.77016909 |
| 86 | MP0003866_abnormal_defecation | 0.74813095 |
| 87 | MP0001529_abnormal_vocalization | 0.74584488 |
| 88 | MP0005075_abnormal_melanosome_morpholog | 0.73768349 |
| 89 | MP0002233_abnormal_nose_morphology | 0.70636702 |
| 90 | MP0000427_abnormal_hair_cycle | 0.70138623 |
| 91 | MP0000631_abnormal_neuroendocrine_gland | 0.68624853 |
| 92 | MP0001502_abnormal_circadian_rhythm | 0.67978459 |
| 93 | MP0005195_abnormal_posterior_eye | 0.66288758 |
| 94 | MP0002752_abnormal_somatic_nervous | 0.65119264 |
| 95 | MP0004145_abnormal_muscle_electrophysio | 0.64042524 |
| 96 | MP0002075_abnormal_coat/hair_pigmentati | 0.63987695 |
| 97 | MP0002572_abnormal_emotion/affect_behav | 0.63746288 |
| 98 | MP0000538_abnormal_urinary_bladder | 0.63518403 |
| 99 | MP0002184_abnormal_innervation | 0.62513935 |
| 100 | MP0001984_abnormal_olfaction | 0.60384615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hypoglycemic seizures (HP:0002173) | 5.90928524 |
| 2 | Reticulocytopenia (HP:0001896) | 4.23407258 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.97248248 |
| 4 | Symptomatic seizures (HP:0011145) | 3.94788674 |
| 5 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.84368197 |
| 6 | Acute encephalopathy (HP:0006846) | 3.58332048 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.49944550 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.40363113 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.40363113 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.39173318 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.30074116 |
| 12 | Macrocytic anemia (HP:0001972) | 3.27301359 |
| 13 | Abnormal number of erythroid precursors (HP:0012131) | 3.24574620 |
| 14 | Pancreatic cysts (HP:0001737) | 3.21492191 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.20253448 |
| 16 | Asplenia (HP:0001746) | 3.15821618 |
| 17 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.11665033 |
| 18 | Increased CSF lactate (HP:0002490) | 3.10221974 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.02591015 |
| 20 | Lipid accumulation in hepatocytes (HP:0006561) | 2.98941243 |
| 21 | Pallor (HP:0000980) | 2.78921565 |
| 22 | IgG deficiency (HP:0004315) | 2.77624609 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.77612395 |
| 24 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.74187860 |
| 25 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.74187860 |
| 26 | Increased intramyocellular lipid droplets (HP:0012240) | 2.73981523 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.70427892 |
| 28 | Hepatocellular necrosis (HP:0001404) | 2.68022495 |
| 29 | Abnormal drinking behavior (HP:0030082) | 2.66023155 |
| 30 | Polydipsia (HP:0001959) | 2.66023155 |
| 31 | Pendular nystagmus (HP:0012043) | 2.64194332 |
| 32 | Medial flaring of the eyebrow (HP:0010747) | 2.64129769 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.57502234 |
| 34 | Increased IgM level (HP:0003496) | 2.57174886 |
| 35 | Abnormality of DNA repair (HP:0003254) | 2.56909187 |
| 36 | Cerebral edema (HP:0002181) | 2.53811216 |
| 37 | Congenital stationary night blindness (HP:0007642) | 2.52666369 |
| 38 | Abnormal protein glycosylation (HP:0012346) | 2.51825361 |
| 39 | Abnormal glycosylation (HP:0012345) | 2.51825361 |
| 40 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.51825361 |
| 41 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.51825361 |
| 42 | Nephronophthisis (HP:0000090) | 2.51310463 |
| 43 | 3-Methylglutaconic aciduria (HP:0003535) | 2.48273643 |
| 44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.46339119 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.44631795 |
| 46 | Attenuation of retinal blood vessels (HP:0007843) | 2.42680637 |
| 47 | Gait imbalance (HP:0002141) | 2.41749415 |
| 48 | Optic disc pallor (HP:0000543) | 2.40671448 |
| 49 | Congenital primary aphakia (HP:0007707) | 2.38542789 |
| 50 | Hepatic necrosis (HP:0002605) | 2.37735855 |
| 51 | Stomatitis (HP:0010280) | 2.36853914 |
| 52 | Colon cancer (HP:0003003) | 2.32853399 |
| 53 | Lactic acidosis (HP:0003128) | 2.28387391 |
| 54 | Increased serum lactate (HP:0002151) | 2.27348669 |
| 55 | Abnormality of the renal medulla (HP:0100957) | 2.27075751 |
| 56 | Type II lissencephaly (HP:0007260) | 2.26990717 |
| 57 | True hermaphroditism (HP:0010459) | 2.26409414 |
| 58 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.24945121 |
| 59 | Absent thumb (HP:0009777) | 2.22102454 |
| 60 | Polyuria (HP:0000103) | 2.20824877 |
| 61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.17983492 |
| 62 | Nephrogenic diabetes insipidus (HP:0009806) | 2.17618914 |
| 63 | Abolished electroretinogram (ERG) (HP:0000550) | 2.16635357 |
| 64 | Stenosis of the external auditory canal (HP:0000402) | 2.13295345 |
| 65 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.09999790 |
| 66 | Cystic liver disease (HP:0006706) | 2.09423488 |
| 67 | Septo-optic dysplasia (HP:0100842) | 2.08537913 |
| 68 | Renal cortical cysts (HP:0000803) | 2.01549841 |
| 69 | Enlarged kidneys (HP:0000105) | 1.98358540 |
| 70 | Decreased circulating renin level (HP:0003351) | 1.97147371 |
| 71 | Abnormality of the pons (HP:0007361) | 1.95561290 |
| 72 | Limb dystonia (HP:0002451) | 1.95095197 |
| 73 | Abnormality of the labia minora (HP:0012880) | 1.94794161 |
| 74 | Renal Fanconi syndrome (HP:0001994) | 1.94560464 |
| 75 | Anencephaly (HP:0002323) | 1.92361806 |
| 76 | Abnormal biliary tract physiology (HP:0012439) | 1.91728126 |
| 77 | Bile duct proliferation (HP:0001408) | 1.91728126 |
| 78 | Lethargy (HP:0001254) | 1.90265306 |
| 79 | Exercise intolerance (HP:0003546) | 1.89583898 |
| 80 | Supernumerary spleens (HP:0009799) | 1.84692582 |
| 81 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.83631914 |
| 82 | Facial hemangioma (HP:0000329) | 1.83225963 |
| 83 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.82952691 |
| 84 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.82952691 |
| 85 | Depressed nasal ridge (HP:0000457) | 1.81372063 |
| 86 | Porencephaly (HP:0002132) | 1.80706679 |
| 87 | Increased corneal curvature (HP:0100692) | 1.80078946 |
| 88 | Keratoconus (HP:0000563) | 1.80078946 |
| 89 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.76768690 |
| 90 | Abnormal urine output (HP:0012590) | 1.76622238 |
| 91 | Sclerocornea (HP:0000647) | 1.76249234 |
| 92 | Poikiloderma (HP:0001029) | 1.75457749 |
| 93 | Hypoplasia of the radius (HP:0002984) | 1.75081410 |
| 94 | Hypoplasia of the pons (HP:0012110) | 1.74581601 |
| 95 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.73345883 |
| 96 | Postaxial foot polydactyly (HP:0001830) | 1.72477418 |
| 97 | Hypoplasia of the ulna (HP:0003022) | 1.70289699 |
| 98 | Reduced antithrombin III activity (HP:0001976) | 1.69470016 |
| 99 | Panhypogammaglobulinemia (HP:0003139) | 1.68517667 |
| 100 | Leukodystrophy (HP:0002415) | 1.67799493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 4.90765067 |
| 2 | ADRBK2 | 3.57878804 |
| 3 | WNK4 | 3.52898212 |
| 4 | STK39 | 3.09537945 |
| 5 | BCKDK | 3.01050199 |
| 6 | TAOK3 | 2.53923871 |
| 7 | GRK1 | 2.42339505 |
| 8 | TXK | 2.41369088 |
| 9 | NEK1 | 2.20807244 |
| 10 | STK16 | 2.16272680 |
| 11 | ZAK | 2.07100763 |
| 12 | DYRK2 | 2.06347434 |
| 13 | NUAK1 | 1.84788565 |
| 14 | ABL2 | 1.83005081 |
| 15 | VRK2 | 1.80174917 |
| 16 | MAP4K2 | 1.70043122 |
| 17 | OXSR1 | 1.68386945 |
| 18 | MAP2K6 | 1.56478377 |
| 19 | NME2 | 1.55501792 |
| 20 | PRKD2 | 1.51211993 |
| 21 | PDK2 | 1.46779875 |
| 22 | FRK | 1.43664770 |
| 23 | MAP2K2 | 1.42731762 |
| 24 | ADRBK1 | 1.34523955 |
| 25 | TEC | 1.21377971 |
| 26 | MAP3K14 | 1.20149234 |
| 27 | NME1 | 1.16792663 |
| 28 | WNK1 | 1.16065429 |
| 29 | PRKCQ | 1.12571745 |
| 30 | CDK19 | 1.10671272 |
| 31 | CAMKK2 | 1.09486558 |
| 32 | WNK3 | 1.07027566 |
| 33 | LRRK2 | 1.06231671 |
| 34 | PASK | 1.06002598 |
| 35 | BMPR1B | 1.03581228 |
| 36 | LIMK1 | 1.02477861 |
| 37 | IKBKB | 1.02402197 |
| 38 | NTRK3 | 1.01996474 |
| 39 | ERBB2 | 1.01621407 |
| 40 | VRK1 | 0.96076427 |
| 41 | TBK1 | 0.95163072 |
| 42 | FES | 0.91188111 |
| 43 | TIE1 | 0.88357538 |
| 44 | AURKB | 0.88215313 |
| 45 | RPS6KA5 | 0.86798838 |
| 46 | IKBKE | 0.84931317 |
| 47 | KDR | 0.84322562 |
| 48 | MAPK13 | 0.83385704 |
| 49 | PINK1 | 0.83176224 |
| 50 | PHKG1 | 0.81361543 |
| 51 | PHKG2 | 0.81361543 |
| 52 | DAPK3 | 0.80597813 |
| 53 | INSRR | 0.79594626 |
| 54 | CLK1 | 0.76220395 |
| 55 | MST4 | 0.72252147 |
| 56 | PRKCG | 0.71404498 |
| 57 | PIM2 | 0.70805086 |
| 58 | CAMK1 | 0.69473878 |
| 59 | LYN | 0.68954024 |
| 60 | LCK | 0.67355301 |
| 61 | MAP4K1 | 0.67154671 |
| 62 | MAP3K11 | 0.66214954 |
| 63 | SRPK1 | 0.65441819 |
| 64 | ITK | 0.62299394 |
| 65 | BUB1 | 0.60844968 |
| 66 | GRK6 | 0.60481207 |
| 67 | PIM1 | 0.59423035 |
| 68 | MATK | 0.56734146 |
| 69 | PIK3CA | 0.54955830 |
| 70 | PLK3 | 0.54222690 |
| 71 | MAPKAPK3 | 0.51729586 |
| 72 | PRKACA | 0.51697673 |
| 73 | EIF2AK2 | 0.51589048 |
| 74 | PLK1 | 0.51537753 |
| 75 | CSNK2A2 | 0.51511112 |
| 76 | CSNK2A1 | 0.49811012 |
| 77 | EIF2AK1 | 0.48705732 |
| 78 | ATR | 0.48284914 |
| 79 | MAPKAPK5 | 0.48194336 |
| 80 | OBSCN | 0.46175734 |
| 81 | TAF1 | 0.45006596 |
| 82 | RPS6KA6 | 0.44778052 |
| 83 | CSNK1E | 0.44005667 |
| 84 | FGFR2 | 0.43423717 |
| 85 | PRKCI | 0.41218159 |
| 86 | AURKA | 0.38702445 |
| 87 | BTK | 0.38059613 |
| 88 | MAP3K12 | 0.37511964 |
| 89 | TGFBR1 | 0.37312440 |
| 90 | PRKCA | 0.35930120 |
| 91 | CDC7 | 0.35710481 |
| 92 | PBK | 0.33203594 |
| 93 | PRKCD | 0.32714084 |
| 94 | CSF1R | 0.32288799 |
| 95 | MKNK1 | 0.31298585 |
| 96 | SYK | 0.30881939 |
| 97 | CAMK2A | 0.30692083 |
| 98 | GRK5 | 0.30587079 |
| 99 | KIT | 0.30199589 |
| 100 | CHEK2 | 0.29961028 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.16599276 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 3.39514434 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.19273064 |
| 4 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.11036670 |
| 5 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.07035035 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.57005424 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.55924393 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.13393696 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 1.98313520 |
| 10 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.92469695 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 1.90911155 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.77396268 |
| 13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.75468858 |
| 14 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.72412866 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.72110459 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.70772527 |
| 17 | Alzheimers disease_Homo sapiens_hsa05010 | 1.69005663 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.65657900 |
| 19 | DNA replication_Homo sapiens_hsa03030 | 1.65488857 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.65125049 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.58524742 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.53620103 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.52234223 |
| 24 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.51573787 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.49330860 |
| 26 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.44864623 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.43493327 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43129163 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.40581013 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.37529876 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.36557448 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.34692359 |
| 33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.28993721 |
| 34 | Asthma_Homo sapiens_hsa05310 | 1.27725186 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.27356418 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.18896336 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 1.11209466 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.07183067 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.06198387 |
| 40 | Allograft rejection_Homo sapiens_hsa05330 | 1.02534823 |
| 41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.00718230 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.98944949 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.94828472 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.92625363 |
| 45 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.89806146 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89370638 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.88802328 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.87347932 |
| 49 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.87144530 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86418621 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.85530081 |
| 52 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.83829470 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.78054509 |
| 54 | Spliceosome_Homo sapiens_hsa03040 | 0.76034378 |
| 55 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75725798 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74900020 |
| 57 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.71328798 |
| 58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71317977 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69815577 |
| 60 | RNA transport_Homo sapiens_hsa03013 | 0.69697120 |
| 61 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68909988 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68503027 |
| 63 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.63163583 |
| 64 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.62539757 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61040669 |
| 66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.58761116 |
| 67 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.58019969 |
| 68 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54466640 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.53291330 |
| 70 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52531600 |
| 71 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51475260 |
| 72 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.51106101 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48018447 |
| 74 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.47906274 |
| 75 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.47740275 |
| 76 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47146875 |
| 77 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46233050 |
| 78 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.44999503 |
| 79 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.44384232 |
| 80 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.43218386 |
| 81 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41084455 |
| 82 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.40402452 |
| 83 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38196165 |
| 84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.37879147 |
| 85 | Morphine addiction_Homo sapiens_hsa05032 | 0.37446286 |
| 86 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.36685557 |
| 87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36552398 |
| 88 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33986756 |
| 89 | Mineral absorption_Homo sapiens_hsa04978 | 0.33199856 |
| 90 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.29203536 |
| 91 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.27461563 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.27158915 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26894064 |
| 94 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.24027949 |
| 95 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.19190756 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.18993219 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.18741034 |
| 98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18255195 |
| 99 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.17872509 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.17662109 |

