RPL9P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.35018267
2DNA deamination (GO:0045006)5.11229099
3viral transcription (GO:0019083)4.72351146
4ribosomal large subunit biogenesis (GO:0042273)4.64605799
5translational termination (GO:0006415)4.59929310
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.18750493
7translational elongation (GO:0006414)4.10688948
8cotranslational protein targeting to membrane (GO:0006613)4.10159756
9protein neddylation (GO:0045116)4.07582039
10protein targeting to ER (GO:0045047)4.05696762
11energy coupled proton transport, down electrochemical gradient (GO:0015985)3.97683634
12ATP synthesis coupled proton transport (GO:0015986)3.97683634
13protein localization to endoplasmic reticulum (GO:0070972)3.88802895
14establishment of protein localization to endoplasmic reticulum (GO:0072599)3.85755423
15maturation of SSU-rRNA (GO:0030490)3.85162533
16protein complex biogenesis (GO:0070271)3.75161006
17water-soluble vitamin biosynthetic process (GO:0042364)3.63283918
18mitochondrial respiratory chain complex I assembly (GO:0032981)3.52303916
19NADH dehydrogenase complex assembly (GO:0010257)3.52303916
20mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.52303916
21piRNA metabolic process (GO:0034587)3.52254291
22chaperone-mediated protein transport (GO:0072321)3.50167818
23cellular protein complex disassembly (GO:0043624)3.48324859
24mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.47710556
25viral life cycle (GO:0019058)3.40944369
26nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.40639547
27tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.40445323
28RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.40445323
29mitochondrial respiratory chain complex assembly (GO:0033108)3.35901614
30GTP biosynthetic process (GO:0006183)3.34636691
31nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.34454277
32positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.34192821
33mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.33331049
34cytidine deamination (GO:0009972)3.23037591
35cytidine metabolic process (GO:0046087)3.23037591
36cytidine catabolic process (GO:0006216)3.23037591
37translational initiation (GO:0006413)3.20466753
38behavioral response to nicotine (GO:0035095)3.16296321
39exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.16073565
40regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.11586129
41regulation of sarcomere organization (GO:0060297)3.09732793
42ribosomal small subunit biogenesis (GO:0042274)3.09248227
43translation (GO:0006412)3.08522206
44positive regulation of prostaglandin secretion (GO:0032308)3.03827498
45positive regulation of oligodendrocyte differentiation (GO:0048714)3.00406539
46regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.98777988
47epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.98739484
48DNA double-strand break processing (GO:0000729)2.93523664
49indolalkylamine metabolic process (GO:0006586)2.93039043
50aggressive behavior (GO:0002118)2.87206897
51protein complex disassembly (GO:0043241)2.83076295
52establishment of protein localization to mitochondrial membrane (GO:0090151)2.83064584
53electron transport chain (GO:0022900)2.82901659
54respiratory electron transport chain (GO:0022904)2.81181122
55kynurenine metabolic process (GO:0070189)2.77987711
56cell proliferation in forebrain (GO:0021846)2.77654133
57regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.76744605
58seminiferous tubule development (GO:0072520)2.75781873
59UTP biosynthetic process (GO:0006228)2.75480826
60macromolecular complex disassembly (GO:0032984)2.74783315
61UTP metabolic process (GO:0046051)2.72186310
62GPI anchor metabolic process (GO:0006505)2.71947340
63ubiquinone biosynthetic process (GO:0006744)2.71874754
64positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.69537899
65behavioral response to ethanol (GO:0048149)2.69476032
66platelet dense granule organization (GO:0060155)2.66805245
67positive regulation of fatty acid transport (GO:2000193)2.66711572
68response to pheromone (GO:0019236)2.66668056
69protein targeting to membrane (GO:0006612)2.66286733
70regulation of immunoglobulin secretion (GO:0051023)2.63463623
71RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.63288081
72protein-cofactor linkage (GO:0018065)2.62802987
73cellular component biogenesis (GO:0044085)2.62380666
74respiratory chain complex IV assembly (GO:0008535)2.61613424
75nuclear-transcribed mRNA catabolic process (GO:0000956)2.61563841
76left/right axis specification (GO:0070986)2.59592162
77positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.58124563
78cytochrome complex assembly (GO:0017004)2.57868170
79pyrimidine ribonucleoside catabolic process (GO:0046133)2.57285522
80purine nucleoside triphosphate biosynthetic process (GO:0009145)2.56676509
81detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.56347692
82positive regulation of icosanoid secretion (GO:0032305)2.56329735
83axoneme assembly (GO:0035082)2.55753862
84purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.55301828
85tRNA processing (GO:0008033)2.53739731
86negative regulation of telomere maintenance (GO:0032205)2.52717492
87parturition (GO:0007567)2.52006885
88GPI anchor biosynthetic process (GO:0006506)2.51274903
89forebrain morphogenesis (GO:0048853)2.50353796
90base-excision repair, AP site formation (GO:0006285)2.50278372
91cellular ketone body metabolic process (GO:0046950)2.50047000
92tryptophan catabolic process (GO:0006569)2.49518209
93indole-containing compound catabolic process (GO:0042436)2.49518209
94indolalkylamine catabolic process (GO:0046218)2.49518209
95proteasome assembly (GO:0043248)2.49062006
96pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.47127410
97aldehyde catabolic process (GO:0046185)2.45725309
98mRNA catabolic process (GO:0006402)2.44047291
99regulation of chronic inflammatory response (GO:0002676)2.43631604
100ubiquinone metabolic process (GO:0006743)2.39033305

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.45968686
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.25887391
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.07253971
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.02648001
5VDR_22108803_ChIP-Seq_LS180_Human3.00654606
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.77437497
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.75096326
8EZH2_22144423_ChIP-Seq_EOC_Human2.71226358
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.69175311
10IGF1R_20145208_ChIP-Seq_DFB_Human2.46799764
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.34632305
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.24356893
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.19213797
14FUS_26573619_Chip-Seq_HEK293_Human2.03667933
15VDR_23849224_ChIP-Seq_CD4+_Human2.00794534
16ELK1_19687146_ChIP-ChIP_HELA_Human2.00416376
17EWS_26573619_Chip-Seq_HEK293_Human2.00044140
18ETS1_20019798_ChIP-Seq_JURKAT_Human1.95104319
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88309810
20EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.87232885
21IRF1_19129219_ChIP-ChIP_H3396_Human1.79935212
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.78810573
23TAF15_26573619_Chip-Seq_HEK293_Human1.78216319
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.72029901
25CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71517297
26MYC_18940864_ChIP-ChIP_HL60_Human1.70395686
27IRF8_22096565_ChIP-ChIP_GC-B_Human1.68881898
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.68503953
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.65490283
30TP53_22573176_ChIP-Seq_HFKS_Human1.64701515
31FOXP3_21729870_ChIP-Seq_TREG_Human1.63463366
32P300_19829295_ChIP-Seq_ESCs_Human1.58579512
33ER_23166858_ChIP-Seq_MCF-7_Human1.53980447
34PCGF2_27294783_Chip-Seq_NPCs_Mouse1.49946352
35FOXA1_27270436_Chip-Seq_PROSTATE_Human1.48293065
36FOXA1_25329375_ChIP-Seq_VCAP_Human1.48293065
37NOTCH1_21737748_ChIP-Seq_TLL_Human1.45605586
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.45111257
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.44821393
40NANOG_19829295_ChIP-Seq_ESCs_Human1.42404811
41SOX2_19829295_ChIP-Seq_ESCs_Human1.42404811
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.40688811
43GBX2_23144817_ChIP-Seq_PC3_Human1.38494557
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.36632084
45SRF_21415370_ChIP-Seq_HL-1_Mouse1.34929184
46GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34533723
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.33302392
48CBP_20019798_ChIP-Seq_JUKART_Human1.33302392
49CBX2_27304074_Chip-Seq_ESCs_Mouse1.32499093
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30637137
51CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.29841806
52RNF2_27304074_Chip-Seq_NSC_Mouse1.28851444
53BMI1_23680149_ChIP-Seq_NPCS_Mouse1.28665992
54AR_20517297_ChIP-Seq_VCAP_Human1.27110887
55CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.25110108
56BCAT_22108803_ChIP-Seq_LS180_Human1.24801095
57GATA3_21878914_ChIP-Seq_MCF-7_Human1.24473350
58EZH2_27294783_Chip-Seq_NPCs_Mouse1.23730496
59TTF2_22483619_ChIP-Seq_HELA_Human1.23139002
60CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.21988363
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.21812026
62EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21790749
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21786003
64NCOR_22424771_ChIP-Seq_293T_Human1.21101516
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.21053383
66GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20870620
67FOXA1_21572438_ChIP-Seq_LNCaP_Human1.19010235
68KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18473402
69PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.15896967
70IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.12550762
71FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.10425032
72TCF4_22108803_ChIP-Seq_LS180_Human1.10174240
73POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09517317
74TAF2_19829295_ChIP-Seq_ESCs_Human1.07846103
75CREB1_15753290_ChIP-ChIP_HEK293T_Human1.07523413
76NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07401205
77CRX_20693478_ChIP-Seq_RETINA_Mouse1.07146767
78GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06884667
79AUTS2_25519132_ChIP-Seq_293T-REX_Human1.06395887
80MYC_18555785_ChIP-Seq_MESCs_Mouse1.05279145
81NANOG_20526341_ChIP-Seq_ESCs_Human1.03746692
82ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02504535
83MYC_19829295_ChIP-Seq_ESCs_Human1.01088149
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01078551
85FOXH1_21741376_ChIP-Seq_EPCs_Human1.00730961
86GATA3_26560356_Chip-Seq_TH2_Human1.00291967
87LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.97845621
88FLI1_21867929_ChIP-Seq_TH2_Mouse0.97139820
89BP1_19119308_ChIP-ChIP_Hs578T_Human0.96834954
90HTT_18923047_ChIP-ChIP_STHdh_Human0.95945488
91PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.95629061
92FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95407389
93POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95373177
94STAT3_18555785_Chip-Seq_ESCs_Mouse0.94965356
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94198438
96PRDM14_20953172_ChIP-Seq_ESCs_Human0.94053484
97TAL1_26923725_Chip-Seq_HPCs_Mouse0.93718400
98P53_22387025_ChIP-Seq_ESCs_Mouse0.93179344
99TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.92642689
100CDX2_22108803_ChIP-Seq_LS180_Human0.92220336

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.47483301
2MP0009379_abnormal_foot_pigmentation4.28268557
3MP0008877_abnormal_DNA_methylation2.58122168
4MP0002102_abnormal_ear_morphology2.37737481
5MP0003880_abnormal_central_pattern2.28112457
6MP0001835_abnormal_antigen_presentation2.28014850
7MP0003787_abnormal_imprinting2.24738676
8MP0002163_abnormal_gland_morphology2.13819476
9MP0005671_abnormal_response_to2.11778774
10MP0006072_abnormal_retinal_apoptosis2.08564899
11MP0008872_abnormal_physiological_respon2.03325659
12MP0000372_irregular_coat_pigmentation2.02938559
13MP0004147_increased_porphyrin_level2.01767687
14MP0005645_abnormal_hypothalamus_physiol1.98897039
15MP0006276_abnormal_autonomic_nervous1.95515771
16MP0004142_abnormal_muscle_tone1.90003123
17MP0002234_abnormal_pharynx_morphology1.89451365
18MP0004145_abnormal_muscle_electrophysio1.88408360
19MP0003806_abnormal_nucleotide_metabolis1.85292107
20MP0005084_abnormal_gallbladder_morpholo1.76729886
21MP0008875_abnormal_xenobiotic_pharmacok1.76412474
22MP0005551_abnormal_eye_electrophysiolog1.73657083
23MP0005646_abnormal_pituitary_gland1.71060520
24MP0002837_dystrophic_cardiac_calcinosis1.70846220
25MP0001968_abnormal_touch/_nociception1.68096030
26MP0002160_abnormal_reproductive_system1.58925280
27MP0003567_abnormal_fetal_cardiomyocyte1.57184026
28MP0001986_abnormal_taste_sensitivity1.46013756
29MP0008789_abnormal_olfactory_epithelium1.43139221
30MP0005379_endocrine/exocrine_gland_phen1.42597527
31MP0008058_abnormal_DNA_repair1.38852684
32MP0002876_abnormal_thyroid_physiology1.34425942
33MP0003646_muscle_fatigue1.34391465
34MP0001529_abnormal_vocalization1.34009164
35MP0005075_abnormal_melanosome_morpholog1.32958160
36MP0002736_abnormal_nociception_after1.32252715
37MP0000631_abnormal_neuroendocrine_gland1.30723483
38MP0001188_hyperpigmentation1.30432815
39MP0008995_early_reproductive_senescence1.30013943
40MP0002148_abnormal_hypersensitivity_rea1.29173207
41MP0003786_premature_aging1.24808500
42MP0002272_abnormal_nervous_system1.23957797
43MP0005253_abnormal_eye_physiology1.23076690
44MP0002653_abnormal_ependyma_morphology1.22017093
45MP0005389_reproductive_system_phenotype1.20472705
46MP0000049_abnormal_middle_ear1.16949949
47MP0001873_stomach_inflammation1.14916374
48MP0001800_abnormal_humoral_immune1.14091436
49MP0003195_calcinosis1.09879333
50MP0004885_abnormal_endolymph1.09657581
51MP0002095_abnormal_skin_pigmentation1.07534260
52MP0001485_abnormal_pinna_reflex1.06865016
53MP0001501_abnormal_sleep_pattern1.03803897
54MP0009764_decreased_sensitivity_to1.03665828
55MP0001293_anophthalmia1.02935187
56MP0009785_altered_susceptibility_to1.02924106
57MP0001905_abnormal_dopamine_level0.98645914
58MP0005410_abnormal_fertilization0.94460839
59MP0001970_abnormal_pain_threshold0.93112645
60MP0000681_abnormal_thyroid_gland0.92472421
61MP0006036_abnormal_mitochondrial_physio0.91703333
62MP0005394_taste/olfaction_phenotype0.91553004
63MP0005499_abnormal_olfactory_system0.91553004
64MP0003121_genomic_imprinting0.90025616
65MP0002735_abnormal_chemical_nociception0.86506357
66MP0001963_abnormal_hearing_physiology0.85325878
67MP0005000_abnormal_immune_tolerance0.84562640
68MP0001764_abnormal_homeostasis0.83413148
69MP0002938_white_spotting0.80746469
70MP0002733_abnormal_thermal_nociception0.80445284
71MP0005670_abnormal_white_adipose0.79812318
72MP0002184_abnormal_innervation0.79522633
73MP0009745_abnormal_behavioral_response0.79463696
74MP0002210_abnormal_sex_determination0.79356145
75MP0006082_CNS_inflammation0.79212538
76MP0001486_abnormal_startle_reflex0.79175695
77MP0002723_abnormal_immune_serum0.78912937
78MP0005387_immune_system_phenotype0.78831191
79MP0001790_abnormal_immune_system0.78831191
80MP0002138_abnormal_hepatobiliary_system0.77333119
81MP0005636_abnormal_mineral_homeostasis0.76504229
82MP0003866_abnormal_defecation0.74296128
83MP0000230_abnormal_systemic_arterial0.73737165
84MP0005195_abnormal_posterior_eye0.73701299
85MP0003122_maternal_imprinting0.73371772
86MP0002557_abnormal_social/conspecific_i0.73324629
87MP0005174_abnormal_tail_pigmentation0.72998117
88MP0002638_abnormal_pupillary_reflex0.72701272
89MP0002752_abnormal_somatic_nervous0.72658402
90MP0003718_maternal_effect0.72076307
91MP0003878_abnormal_ear_physiology0.71329008
92MP0005377_hearing/vestibular/ear_phenot0.71329008
93MP0001819_abnormal_immune_cell0.69891248
94MP0003638_abnormal_response/metabolism_0.69763327
95MP0000026_abnormal_inner_ear0.69310240
96MP0005360_urolithiasis0.69144625
97MP0002452_abnormal_antigen_presenting0.68472558
98MP0002420_abnormal_adaptive_immunity0.68416898
99MP0009250_abnormal_appendicular_skeleto0.68260334
100MP0004742_abnormal_vestibular_system0.66704919

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.00918076
2Mitochondrial inheritance (HP:0001427)3.72455664
3Abnormal mitochondria in muscle tissue (HP:0008316)3.52011079
4Absent rod-and cone-mediated responses on ERG (HP:0007688)3.47420562
5Hepatocellular necrosis (HP:0001404)3.43469854
6Increased CSF lactate (HP:0002490)3.42757410
7Abnormality of midbrain morphology (HP:0002418)3.41337819
8Molar tooth sign on MRI (HP:0002419)3.41337819
9Acute encephalopathy (HP:0006846)3.36362388
10Progressive macrocephaly (HP:0004481)3.27410197
11Reticulocytopenia (HP:0001896)3.12479630
12Increased hepatocellular lipid droplets (HP:0006565)3.12348098
13Abnormal rod and cone electroretinograms (HP:0008323)3.05551985
14Hepatic necrosis (HP:0002605)3.04527175
15Pancreatic cysts (HP:0001737)3.02025040
16Renal Fanconi syndrome (HP:0001994)2.95197343
17Lipid accumulation in hepatocytes (HP:0006561)2.92523790
183-Methylglutaconic aciduria (HP:0003535)2.89085549
19Congenital stationary night blindness (HP:0007642)2.88989655
20Nephronophthisis (HP:0000090)2.84779085
21Pancreatic fibrosis (HP:0100732)2.79455042
22Methylmalonic acidemia (HP:0002912)2.74582504
23Medial flaring of the eyebrow (HP:0010747)2.72919789
24Constricted visual fields (HP:0001133)2.72581387
25Colon cancer (HP:0003003)2.70084588
26Abnormality of cells of the erythroid lineage (HP:0012130)2.63504537
27Type II lissencephaly (HP:0007260)2.62933881
28Optic disc pallor (HP:0000543)2.61205011
29Elevated erythrocyte sedimentation rate (HP:0003565)2.60980315
30Abolished electroretinogram (ERG) (HP:0000550)2.59167736
31True hermaphroditism (HP:0010459)2.57052400
32Hyperglycinemia (HP:0002154)2.56250050
33Macrocytic anemia (HP:0001972)2.54103015
34Abnormality of B cell number (HP:0010975)2.50284204
35Cerebral edema (HP:0002181)2.46537764
36Hypoproteinemia (HP:0003075)2.45708797
37Aplastic anemia (HP:0001915)2.45214647
38IgG deficiency (HP:0004315)2.42108623
39Increased intramyocellular lipid droplets (HP:0012240)2.41817090
40Severe combined immunodeficiency (HP:0004430)2.40370139
41Thyroid-stimulating hormone excess (HP:0002925)2.39769431
42Attenuation of retinal blood vessels (HP:0007843)2.37185295
43Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.33742381
44Decreased electroretinogram (ERG) amplitude (HP:0000654)2.30076308
45Abnormality of the renal medulla (HP:0100957)2.27104534
46Thyroiditis (HP:0100646)2.26938122
47Exertional dyspnea (HP:0002875)2.26665741
48Increased serum lactate (HP:0002151)2.25063146
49Absent/shortened dynein arms (HP:0200106)2.23822769
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.23822769
51Abnormal number of erythroid precursors (HP:0012131)2.21367275
52Stenosis of the external auditory canal (HP:0000402)2.18615892
53Nephrogenic diabetes insipidus (HP:0009806)2.17766274
54Abnormality of the prostate (HP:0008775)2.13670398
55Methylmalonic aciduria (HP:0012120)2.13152990
56Rib fusion (HP:0000902)2.12944209
57Panhypogammaglobulinemia (HP:0003139)2.11915695
58Volvulus (HP:0002580)2.11474767
59Abnormality of renal resorption (HP:0011038)2.11334882
60Stomatitis (HP:0010280)2.09725911
61Cystic liver disease (HP:0006706)2.04885395
62Lactic acidosis (HP:0003128)2.04001723
63Abnormality of the renal cortex (HP:0011035)2.02218671
64B lymphocytopenia (HP:0010976)2.02103933
65Increased IgM level (HP:0003496)2.01171805
66Intestinal atresia (HP:0011100)2.00318946
67Tachypnea (HP:0002789)1.99805272
68Abnormal hemoglobin (HP:0011902)1.99509088
69Increased muscle lipid content (HP:0009058)1.98284874
70Pallor (HP:0000980)1.96699607
71Abnormality of the labia minora (HP:0012880)1.95946372
72Lethargy (HP:0001254)1.94768323
73Lissencephaly (HP:0001339)1.92995401
74Congenital, generalized hypertrichosis (HP:0004540)1.92162041
75Abnormality of DNA repair (HP:0003254)1.90529605
76Decreased central vision (HP:0007663)1.89782325
77Abnormality of macular pigmentation (HP:0008002)1.89465399
78Glycosuria (HP:0003076)1.89318599
79Abnormality of urine glucose concentration (HP:0011016)1.89318599
80Triphalangeal thumb (HP:0001199)1.88897675
81Abnormality of serine family amino acid metabolism (HP:0010894)1.88447385
82Abnormality of glycine metabolism (HP:0010895)1.88447385
83Pendular nystagmus (HP:0012043)1.88132641
84Gait imbalance (HP:0002141)1.87078203
85Congenital primary aphakia (HP:0007707)1.86825480
86Bony spicule pigmentary retinopathy (HP:0007737)1.86787583
87Abnormal respiratory motile cilium morphology (HP:0005938)1.86577250
88Abnormal respiratory epithelium morphology (HP:0012253)1.86577250
89Renal cortical cysts (HP:0000803)1.85941938
90Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.84094346
91Metaphyseal dysplasia (HP:0100255)1.81938239
92Abnormal biliary tract physiology (HP:0012439)1.80891422
93Bile duct proliferation (HP:0001408)1.80891422
94Abnormality of the phalanges of the 5th finger (HP:0004213)1.80177791
95Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.79892751
96Polydipsia (HP:0001959)1.79413829
97Abnormal drinking behavior (HP:0030082)1.79413829
98Absent thumb (HP:0009777)1.79024882
99Hyperglycinuria (HP:0003108)1.76639463
100Abnormality of eosinophils (HP:0001879)1.76553947

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K23.84072393
2CDK193.78406095
3VRK23.06322780
4ADRBK22.55835629
5TAOK32.54732640
6TXK2.31758834
7FRK2.31512343
8TEC2.18156081
9BCKDK2.09085288
10NUAK12.00778283
11PINK11.92305409
12WNK41.85163764
13ZAK1.84959112
14GRK11.79315595
15VRK11.75733086
16WNK31.74303427
17MAPK131.73535999
18OXSR11.69275380
19STK38L1.68599171
20TIE11.64631852
21ITK1.63101126
22STK161.53913216
23KIT1.50822702
24PASK1.49183440
25DYRK21.47266372
26KDR1.40151108
27BMPR1B1.24842714
28CSNK1G21.19166593
29TLK11.14446713
30TAF11.12224329
31STK391.09889648
32PLK41.09200905
33CSNK1G31.08405567
34BTK1.01982274
35SYK1.00189329
36CAMKK20.98820667
37PRKCQ0.98723889
38EIF2AK30.97779099
39INSRR0.96846710
40GRK60.91783287
41MATK0.83195423
42CSNK1A1L0.82745622
43CSNK1G10.82314139
44PRKCE0.78616344
45TRIM280.78445900
46MAP4K10.78328663
47ADRBK10.78143036
48IKBKB0.77000780
49MAP3K120.72495640
50EPHA40.70776875
51MUSK0.69493914
52NME10.67131780
53DAPK10.66261181
54PLK20.65999922
55BCR0.65770303
56PLK30.62760236
57DAPK20.62033321
58EIF2AK20.61954233
59LCK0.61898054
60DAPK30.61689197
61MKNK10.61101682
62PRKCG0.60959074
63OBSCN0.60129777
64MAP2K60.56889513
65RPS6KA50.56273243
66PIK3CA0.55989483
67FLT30.55077044
68LYN0.54782297
69CSNK2A20.54399284
70CSF1R0.54093358
71ATR0.53162513
72PRKACA0.52882147
73CSNK2A10.51913323
74MYLK0.50672928
75CASK0.50639089
76IGF1R0.50260784
77PIK3CG0.49537512
78EPHA30.49345998
79CAMKK10.48673395
80TNK20.48224895
81MAP2K70.47920686
82PHKG10.46177576
83PHKG20.46177576
84CAMK2A0.45266902
85PRKCA0.44888560
86MAP3K40.44865440
87UHMK10.43873255
88PBK0.43319391
89BMPR20.41456162
90CSNK1A10.41245979
91MARK10.40179106
92PIM10.39117026
93GRK50.38832103
94CAMK10.36539846
95RPS6KA60.36163885
96PIM20.35690056
97PLK10.35200869
98MKNK20.35174329
99PRKG10.35047952
100AURKB0.34530114

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.89857595
2Asthma_Homo sapiens_hsa053103.85332623
3Allograft rejection_Homo sapiens_hsa053303.10772494
4Oxidative phosphorylation_Homo sapiens_hsa001902.93628944
5Autoimmune thyroid disease_Homo sapiens_hsa053202.82335982
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.78476716
7Protein export_Homo sapiens_hsa030602.69492406
8Type I diabetes mellitus_Homo sapiens_hsa049402.65019697
9Graft-versus-host disease_Homo sapiens_hsa053322.41071629
10Parkinsons disease_Homo sapiens_hsa050122.37948915
11Proteasome_Homo sapiens_hsa030502.37540306
12Primary immunodeficiency_Homo sapiens_hsa053402.24605742
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.04662702
14Linoleic acid metabolism_Homo sapiens_hsa005911.86982559
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.85367563
16Homologous recombination_Homo sapiens_hsa034401.81641384
17RNA polymerase_Homo sapiens_hsa030201.74849114
18Fanconi anemia pathway_Homo sapiens_hsa034601.69100492
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.64194524
20Huntingtons disease_Homo sapiens_hsa050161.60245487
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.59066278
22Alzheimers disease_Homo sapiens_hsa050101.51148297
23Phototransduction_Homo sapiens_hsa047441.41285558
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.34426298
25Antigen processing and presentation_Homo sapiens_hsa046121.30161730
26Propanoate metabolism_Homo sapiens_hsa006401.28791459
27Cardiac muscle contraction_Homo sapiens_hsa042601.27374798
28Rheumatoid arthritis_Homo sapiens_hsa053231.27133805
29Caffeine metabolism_Homo sapiens_hsa002321.26302773
30RNA degradation_Homo sapiens_hsa030181.25450714
31Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.23400884
32Arachidonic acid metabolism_Homo sapiens_hsa005901.17659709
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.17297420
34Hematopoietic cell lineage_Homo sapiens_hsa046401.17206475
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.11986701
36Basal transcription factors_Homo sapiens_hsa030221.11054025
37Mismatch repair_Homo sapiens_hsa034301.10064308
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.09163218
39Ether lipid metabolism_Homo sapiens_hsa005651.08610569
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07579561
41Nucleotide excision repair_Homo sapiens_hsa034201.07194129
42Olfactory transduction_Homo sapiens_hsa047401.06200041
43Tryptophan metabolism_Homo sapiens_hsa003801.04582273
44Butanoate metabolism_Homo sapiens_hsa006501.02321337
45Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.01175665
46Peroxisome_Homo sapiens_hsa041460.99705779
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.99162046
48Pyrimidine metabolism_Homo sapiens_hsa002400.93955613
49Non-homologous end-joining_Homo sapiens_hsa034500.91778429
50Chemical carcinogenesis_Homo sapiens_hsa052040.91297037
51Retinol metabolism_Homo sapiens_hsa008300.88797745
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.87195564
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.86287288
54Fat digestion and absorption_Homo sapiens_hsa049750.85735090
55Regulation of autophagy_Homo sapiens_hsa041400.83855653
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.81019018
57Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.80902508
58Viral myocarditis_Homo sapiens_hsa054160.77294358
59Nitrogen metabolism_Homo sapiens_hsa009100.76259380
60Purine metabolism_Homo sapiens_hsa002300.75697707
61RNA transport_Homo sapiens_hsa030130.75670821
62One carbon pool by folate_Homo sapiens_hsa006700.72503637
63Staphylococcus aureus infection_Homo sapiens_hsa051500.72446547
64Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.71849644
65DNA replication_Homo sapiens_hsa030300.71028043
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69310767
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.68938320
68Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67471701
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66995407
70Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.58459269
71Systemic lupus erythematosus_Homo sapiens_hsa053220.57801245
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.56534974
73Salivary secretion_Homo sapiens_hsa049700.55764209
74Nicotine addiction_Homo sapiens_hsa050330.55366192
75Base excision repair_Homo sapiens_hsa034100.54976748
76Metabolic pathways_Homo sapiens_hsa011000.54559837
77Fatty acid degradation_Homo sapiens_hsa000710.53110537
78beta-Alanine metabolism_Homo sapiens_hsa004100.49769267
79Spliceosome_Homo sapiens_hsa030400.48791702
80Taste transduction_Homo sapiens_hsa047420.47827337
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.45631438
82Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.45030614
83Cysteine and methionine metabolism_Homo sapiens_hsa002700.43191469
84Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.43064916
85Collecting duct acid secretion_Homo sapiens_hsa049660.36741505
86Leishmaniasis_Homo sapiens_hsa051400.36244975
87Steroid biosynthesis_Homo sapiens_hsa001000.35947503
88Drug metabolism - other enzymes_Homo sapiens_hsa009830.35595797
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.35115680
90Morphine addiction_Homo sapiens_hsa050320.34009215
91Sulfur metabolism_Homo sapiens_hsa009200.33299842
92African trypanosomiasis_Homo sapiens_hsa051430.30493695
93Ovarian steroidogenesis_Homo sapiens_hsa049130.30386082
94Primary bile acid biosynthesis_Homo sapiens_hsa001200.28899318
95Selenocompound metabolism_Homo sapiens_hsa004500.27437333
96Glutathione metabolism_Homo sapiens_hsa004800.27272762
97Serotonergic synapse_Homo sapiens_hsa047260.26966512
98Circadian entrainment_Homo sapiens_hsa047130.26041632
99Transcriptional misregulation in cancer_Homo sapiens_hsa052020.24153154
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23457228

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