

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | histamine transport (GO:0051608) | 7.90636431 |
| 2 | meiotic chromosome segregation (GO:0045132) | 6.91971878 |
| 3 | drug transmembrane transport (GO:0006855) | 6.69212370 |
| 4 | neurotransmitter biosynthetic process (GO:0042136) | 6.50859469 |
| 5 | organic cation transport (GO:0015695) | 6.44547848 |
| 6 | tooth mineralization (GO:0034505) | 6.44502674 |
| 7 | exogenous drug catabolic process (GO:0042738) | 6.21362631 |
| 8 | quaternary ammonium group transport (GO:0015697) | 6.08323207 |
| 9 | neurotransmitter metabolic process (GO:0042133) | 5.99720007 |
| 10 | behavioral response to nicotine (GO:0035095) | 5.63483449 |
| 11 | resolution of meiotic recombination intermediates (GO:0000712) | 5.60078847 |
| 12 | positive regulation of meiosis (GO:0045836) | 5.20220660 |
| 13 | negative regulation of telomere maintenance (GO:0032205) | 5.03094893 |
| 14 | bone trabecula formation (GO:0060346) | 5.01238584 |
| 15 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 4.96256916 |
| 16 | rRNA catabolic process (GO:0016075) | 4.89417567 |
| 17 | positive regulation of meiotic cell cycle (GO:0051446) | 4.82340861 |
| 18 | drug catabolic process (GO:0042737) | 4.65044823 |
| 19 | azole transport (GO:0045117) | 4.63728437 |
| 20 | drug transport (GO:0015893) | 4.58613326 |
| 21 | regulation of response to tumor cell (GO:0002834) | 4.29316892 |
| 22 | positive regulation of response to tumor cell (GO:0002836) | 4.29316892 |
| 23 | positive regulation of immune response to tumor cell (GO:0002839) | 4.29316892 |
| 24 | regulation of immune response to tumor cell (GO:0002837) | 4.29316892 |
| 25 | fatty acid elongation (GO:0030497) | 4.18949627 |
| 26 | synaptonemal complex assembly (GO:0007130) | 4.14159940 |
| 27 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 4.08981674 |
| 28 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.93907380 |
| 29 | synaptonemal complex organization (GO:0070193) | 3.84054573 |
| 30 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 3.83216285 |
| 31 | kynurenine metabolic process (GO:0070189) | 3.82776793 |
| 32 | reciprocal meiotic recombination (GO:0007131) | 3.80075160 |
| 33 | reciprocal DNA recombination (GO:0035825) | 3.80075160 |
| 34 | positive regulation of hair cycle (GO:0042635) | 3.76243916 |
| 35 | positive regulation of hair follicle development (GO:0051798) | 3.76243916 |
| 36 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.75937845 |
| 37 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.73660582 |
| 38 | histone-serine phosphorylation (GO:0035404) | 3.66707829 |
| 39 | auditory receptor cell stereocilium organization (GO:0060088) | 3.62920372 |
| 40 | maturation of 5.8S rRNA (GO:0000460) | 3.53758428 |
| 41 | L-fucose catabolic process (GO:0042355) | 3.53260364 |
| 42 | fucose catabolic process (GO:0019317) | 3.53260364 |
| 43 | L-fucose metabolic process (GO:0042354) | 3.53260364 |
| 44 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 3.49709821 |
| 45 | C4-dicarboxylate transport (GO:0015740) | 3.44042609 |
| 46 | fatty acid transmembrane transport (GO:1902001) | 3.42273331 |
| 47 | rRNA modification (GO:0000154) | 3.40058387 |
| 48 | indole-containing compound catabolic process (GO:0042436) | 3.40014031 |
| 49 | indolalkylamine catabolic process (GO:0046218) | 3.40014031 |
| 50 | tryptophan catabolic process (GO:0006569) | 3.40014031 |
| 51 | rRNA methylation (GO:0031167) | 3.37310323 |
| 52 | positive regulation of protein homodimerization activity (GO:0090073) | 3.37204753 |
| 53 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.34875397 |
| 54 | DNA deamination (GO:0045006) | 3.23607119 |
| 55 | protein K6-linked ubiquitination (GO:0085020) | 3.20901577 |
| 56 | histone H3-K36 demethylation (GO:0070544) | 3.18318946 |
| 57 | secretory granule organization (GO:0033363) | 3.17717773 |
| 58 | gonadal mesoderm development (GO:0007506) | 3.16411470 |
| 59 | protein neddylation (GO:0045116) | 3.10973891 |
| 60 | gamma-aminobutyric acid transport (GO:0015812) | 3.09657021 |
| 61 | ATP synthesis coupled proton transport (GO:0015986) | 3.09156886 |
| 62 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.09156886 |
| 63 | nephron tubule morphogenesis (GO:0072078) | 3.08934641 |
| 64 | nephron epithelium morphogenesis (GO:0072088) | 3.08934641 |
| 65 | wound healing, spreading of epidermal cells (GO:0035313) | 3.08371053 |
| 66 | regulation of meiosis I (GO:0060631) | 3.06951572 |
| 67 | positive regulation of mast cell activation (GO:0033005) | 3.03871372 |
| 68 | carnitine shuttle (GO:0006853) | 3.03697184 |
| 69 | lysosome localization (GO:0032418) | 2.97753687 |
| 70 | negative regulation of epidermis development (GO:0045683) | 2.97744386 |
| 71 | regulation of chronic inflammatory response (GO:0002676) | 2.95478153 |
| 72 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.94616156 |
| 73 | phenol-containing compound catabolic process (GO:0019336) | 2.92151053 |
| 74 | aromatic amino acid family catabolic process (GO:0009074) | 2.91461942 |
| 75 | parturition (GO:0007567) | 2.90499856 |
| 76 | retinal cone cell development (GO:0046549) | 2.88220685 |
| 77 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.87499999 |
| 78 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.86786248 |
| 79 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.86239226 |
| 80 | cellular response to exogenous dsRNA (GO:0071360) | 2.82441196 |
| 81 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.82296011 |
| 82 | chromosome organization involved in meiosis (GO:0070192) | 2.80505193 |
| 83 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.78623938 |
| 84 | endothelium development (GO:0003158) | 2.77571274 |
| 85 | neurotransmitter catabolic process (GO:0042135) | 2.76732977 |
| 86 | arginine catabolic process (GO:0006527) | 2.75522561 |
| 87 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.74175185 |
| 88 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 2.71512284 |
| 89 | regulation of transcription regulatory region DNA binding (GO:2000677) | 2.68077167 |
| 90 | positive regulation of defense response to virus by host (GO:0002230) | 2.68050265 |
| 91 | positive regulation of guanylate cyclase activity (GO:0031284) | 2.65371300 |
| 92 | ncRNA catabolic process (GO:0034661) | 2.63008874 |
| 93 | piRNA metabolic process (GO:0034587) | 2.62726300 |
| 94 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.62345508 |
| 95 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.60220027 |
| 96 | protein polyglutamylation (GO:0018095) | 2.55908909 |
| 97 | regulation of energy homeostasis (GO:2000505) | 2.53786323 |
| 98 | tryptophan metabolic process (GO:0006568) | 2.52345515 |
| 99 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.51838781 |
| 100 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.49729122 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 7.22886386 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.42302268 |
| 3 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.94498393 |
| 4 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.69388509 |
| 5 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.67164641 |
| 6 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.61109687 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.58942179 |
| 8 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.17036036 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.11624342 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.02818274 |
| 11 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 2.02726254 |
| 12 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.97582428 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.91587316 |
| 14 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.86110946 |
| 15 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.84025729 |
| 16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.72033903 |
| 17 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.70896830 |
| 18 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.68761908 |
| 19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.66341072 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.65039440 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.64574892 |
| 22 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.62027909 |
| 23 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.62027909 |
| 24 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.57178436 |
| 25 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.54635289 |
| 26 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.52575098 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51788810 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.51115177 |
| 29 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.50753221 |
| 30 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.49899413 |
| 31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.49003513 |
| 32 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.48162489 |
| 33 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.46807936 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.45682412 |
| 35 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.44489543 |
| 36 | AR_20517297_ChIP-Seq_VCAP_Human | 1.43007460 |
| 37 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.42921543 |
| 38 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.41716420 |
| 39 | ERA_21632823_ChIP-Seq_H3396_Human | 1.38387672 |
| 40 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.35919388 |
| 41 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.34763413 |
| 42 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.34580318 |
| 43 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.33343903 |
| 44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30762822 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.29748785 |
| 46 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.29306571 |
| 47 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.28883697 |
| 48 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.28099049 |
| 49 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.27269225 |
| 50 | NCOR_22424771_ChIP-Seq_293T_Human | 1.26845876 |
| 51 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.26391453 |
| 52 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.24900072 |
| 53 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.23603903 |
| 54 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.16861060 |
| 55 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.15810944 |
| 56 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14759621 |
| 57 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.14697697 |
| 58 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14489721 |
| 59 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13707056 |
| 60 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.12031033 |
| 61 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.11544624 |
| 62 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.11251071 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10826891 |
| 64 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.10110005 |
| 65 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.09625820 |
| 66 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.08571788 |
| 67 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07718286 |
| 68 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.06896440 |
| 69 | JUN_21703547_ChIP-Seq_K562_Human | 1.06706913 |
| 70 | P300_27268052_Chip-Seq_Bcells_Human | 1.05317031 |
| 71 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04585698 |
| 72 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04585698 |
| 73 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.04306852 |
| 74 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.04143935 |
| 75 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.03372686 |
| 76 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.03283442 |
| 77 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.02141977 |
| 78 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.01832581 |
| 79 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01287352 |
| 80 | P300_19829295_ChIP-Seq_ESCs_Human | 1.00607346 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00501484 |
| 82 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 1.00142910 |
| 83 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.00016258 |
| 84 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.96441344 |
| 85 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.95965049 |
| 86 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.94901569 |
| 87 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.94659298 |
| 88 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94541367 |
| 89 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.92249063 |
| 90 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.90780325 |
| 91 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.89455909 |
| 92 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.89003849 |
| 93 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.88924679 |
| 94 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88812137 |
| 95 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88812137 |
| 96 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.86951438 |
| 97 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.86435312 |
| 98 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.86127842 |
| 99 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85790627 |
| 100 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.85621851 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 6.22700989 |
| 2 | MP0003646_muscle_fatigue | 5.24574865 |
| 3 | MP0002837_dystrophic_cardiac_calcinosis | 3.38713959 |
| 4 | MP0002160_abnormal_reproductive_system | 2.74485155 |
| 5 | MP0002163_abnormal_gland_morphology | 2.55112861 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.50478226 |
| 7 | MP0005645_abnormal_hypothalamus_physiol | 2.44623345 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.43120952 |
| 9 | MP0008872_abnormal_physiological_respon | 2.39628935 |
| 10 | MP0005167_abnormal_blood-brain_barrier | 2.38392060 |
| 11 | MP0002138_abnormal_hepatobiliary_system | 2.33553644 |
| 12 | MP0003329_amyloid_beta_deposits | 2.24569177 |
| 13 | MP0004043_abnormal_pH_regulation | 2.17387933 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 2.14747666 |
| 15 | MP0001919_abnormal_reproductive_system | 2.13216431 |
| 16 | MP0005389_reproductive_system_phenotype | 2.08029827 |
| 17 | MP0001440_abnormal_grooming_behavior | 1.93020371 |
| 18 | MP0006292_abnormal_olfactory_placode | 1.88823182 |
| 19 | MP0000604_amyloidosis | 1.86151138 |
| 20 | MP0001835_abnormal_antigen_presentation | 1.76034959 |
| 21 | MP0005551_abnormal_eye_electrophysiolog | 1.72750826 |
| 22 | MP0003195_calcinosis | 1.72504624 |
| 23 | MP0003136_yellow_coat_color | 1.71600643 |
| 24 | MP0000049_abnormal_middle_ear | 1.69711130 |
| 25 | MP0004381_abnormal_hair_follicle | 1.67364525 |
| 26 | MP0001873_stomach_inflammation | 1.66689801 |
| 27 | MP0006276_abnormal_autonomic_nervous | 1.60272388 |
| 28 | MP0005085_abnormal_gallbladder_physiolo | 1.53537267 |
| 29 | MP0004147_increased_porphyrin_level | 1.53048564 |
| 30 | MP0004145_abnormal_muscle_electrophysio | 1.52797603 |
| 31 | MP0004885_abnormal_endolymph | 1.52553596 |
| 32 | MP0005379_endocrine/exocrine_gland_phen | 1.50298251 |
| 33 | MP0001664_abnormal_digestion | 1.42404673 |
| 34 | MP0004858_abnormal_nervous_system | 1.39520548 |
| 35 | MP0002876_abnormal_thyroid_physiology | 1.34734056 |
| 36 | MP0005671_abnormal_response_to | 1.34570340 |
| 37 | MP0009745_abnormal_behavioral_response | 1.33604318 |
| 38 | MP0001986_abnormal_taste_sensitivity | 1.33153000 |
| 39 | MP0005410_abnormal_fertilization | 1.32933372 |
| 40 | MP0002102_abnormal_ear_morphology | 1.32544594 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.30838263 |
| 42 | MP0009379_abnormal_foot_pigmentation | 1.30393790 |
| 43 | MP0005387_immune_system_phenotype | 1.29901556 |
| 44 | MP0001790_abnormal_immune_system | 1.29901556 |
| 45 | MP0008775_abnormal_heart_ventricle | 1.29786105 |
| 46 | MP0001968_abnormal_touch/_nociception | 1.23728136 |
| 47 | MP0003252_abnormal_bile_duct | 1.20545168 |
| 48 | MP0004130_abnormal_muscle_cell | 1.20448255 |
| 49 | MP0006036_abnormal_mitochondrial_physio | 1.17695070 |
| 50 | MP0005084_abnormal_gallbladder_morpholo | 1.16551320 |
| 51 | MP0002272_abnormal_nervous_system | 1.16275981 |
| 52 | MP0009764_decreased_sensitivity_to | 1.13605054 |
| 53 | MP0004142_abnormal_muscle_tone | 1.13231062 |
| 54 | MP0000685_abnormal_immune_system | 1.12545021 |
| 55 | MP0002234_abnormal_pharynx_morphology | 1.10552049 |
| 56 | MP0000427_abnormal_hair_cycle | 1.07963238 |
| 57 | MP0004084_abnormal_cardiac_muscle | 1.05582008 |
| 58 | MP0002733_abnormal_thermal_nociception | 1.05134117 |
| 59 | MP0002148_abnormal_hypersensitivity_rea | 1.01322527 |
| 60 | MP0002557_abnormal_social/conspecific_i | 1.00783612 |
| 61 | MP0003718_maternal_effect | 0.96342008 |
| 62 | MP0005266_abnormal_metabolism | 0.96266290 |
| 63 | MP0001501_abnormal_sleep_pattern | 0.95028185 |
| 64 | MP0000470_abnormal_stomach_morphology | 0.94374525 |
| 65 | MP0004742_abnormal_vestibular_system | 0.89364125 |
| 66 | MP0005195_abnormal_posterior_eye | 0.88694078 |
| 67 | MP0001663_abnormal_digestive_system | 0.88546016 |
| 68 | MP0002254_reproductive_system_inflammat | 0.87188189 |
| 69 | MP0009643_abnormal_urine_homeostasis | 0.86784615 |
| 70 | MP0001963_abnormal_hearing_physiology | 0.84931744 |
| 71 | MP0005408_hypopigmentation | 0.84222253 |
| 72 | MP0002139_abnormal_hepatobiliary_system | 0.83941900 |
| 73 | MP0005332_abnormal_amino_acid | 0.83690083 |
| 74 | MP0010329_abnormal_lipoprotein_level | 0.83274794 |
| 75 | MP0009046_muscle_twitch | 0.83170254 |
| 76 | MP0005646_abnormal_pituitary_gland | 0.79939329 |
| 77 | MP0001756_abnormal_urination | 0.78936929 |
| 78 | MP0001970_abnormal_pain_threshold | 0.77728010 |
| 79 | MP0004484_altered_response_of | 0.75703807 |
| 80 | MP0002572_abnormal_emotion/affect_behav | 0.72293943 |
| 81 | MP0002210_abnormal_sex_determination | 0.71643424 |
| 82 | MP0005365_abnormal_bile_salt | 0.71561126 |
| 83 | MP0002752_abnormal_somatic_nervous | 0.70153533 |
| 84 | MP0002095_abnormal_skin_pigmentation | 0.69377158 |
| 85 | MP0002932_abnormal_joint_morphology | 0.68567457 |
| 86 | MP0009333_abnormal_splenocyte_physiolog | 0.68190195 |
| 87 | MP0005360_urolithiasis | 0.65234482 |
| 88 | MP0003787_abnormal_imprinting | 0.65156284 |
| 89 | MP0001286_abnormal_eye_development | 0.64660405 |
| 90 | MP0002063_abnormal_learning/memory/cond | 0.63153557 |
| 91 | MP0003632_abnormal_nervous_system | 0.62394433 |
| 92 | MP0003693_abnormal_embryo_hatching | 0.62217650 |
| 93 | MP0005647_abnormal_sex_gland | 0.61979871 |
| 94 | MP0001348_abnormal_lacrimal_gland | 0.61845125 |
| 95 | MP0002938_white_spotting | 0.61415893 |
| 96 | MP0004233_abnormal_muscle_weight | 0.60152007 |
| 97 | MP0001764_abnormal_homeostasis | 0.59967579 |
| 98 | MP0003045_fibrosis | 0.59949335 |
| 99 | MP0003186_abnormal_redox_activity | 0.59818301 |
| 100 | MP0001800_abnormal_humoral_immune | 0.58817385 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 6.57143341 |
| 2 | Hypoplasia of the fovea (HP:0007750) | 6.57143341 |
| 3 | Bilateral microphthalmos (HP:0007633) | 6.21629049 |
| 4 | Unilateral renal agenesis (HP:0000122) | 6.19074795 |
| 5 | Conjugated hyperbilirubinemia (HP:0002908) | 5.42564495 |
| 6 | Abnormality of the fovea (HP:0000493) | 5.13178927 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 4.51062627 |
| 8 | Aplasia/Hypoplasia of the macula (HP:0008059) | 4.46132388 |
| 9 | Aplasia cutis congenita (HP:0001057) | 4.29354271 |
| 10 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 4.21658236 |
| 11 | Fused cervical vertebrae (HP:0002949) | 3.94141681 |
| 12 | Progressive inability to walk (HP:0002505) | 3.79715448 |
| 13 | Stomatitis (HP:0010280) | 3.64774019 |
| 14 | Congenital stationary night blindness (HP:0007642) | 3.60786455 |
| 15 | Abnormality of the right ventricle (HP:0001707) | 3.17646444 |
| 16 | Tubular atrophy (HP:0000092) | 3.09349236 |
| 17 | Lissencephaly (HP:0001339) | 3.02745256 |
| 18 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.99503210 |
| 19 | Inability to walk (HP:0002540) | 2.95194739 |
| 20 | Concave nail (HP:0001598) | 2.93039699 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.82123436 |
| 22 | Abnormality of midbrain morphology (HP:0002418) | 2.82123436 |
| 23 | Type II lissencephaly (HP:0007260) | 2.80335656 |
| 24 | Abnormality of the parietal bone (HP:0002696) | 2.80137074 |
| 25 | Decreased central vision (HP:0007663) | 2.76942957 |
| 26 | Mixed hearing impairment (HP:0000410) | 2.72502606 |
| 27 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.63462986 |
| 28 | Abnormality of transition element cation homeostasis (HP:0011030) | 2.59580133 |
| 29 | Widely patent fontanelles and sutures (HP:0004492) | 2.58983107 |
| 30 | CNS hypomyelination (HP:0003429) | 2.55645385 |
| 31 | Increased hepatocellular lipid droplets (HP:0006565) | 2.54282378 |
| 32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.51539793 |
| 33 | Acute necrotizing encephalopathy (HP:0006965) | 2.47719507 |
| 34 | Type 2 muscle fiber atrophy (HP:0003554) | 2.46877216 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.45441779 |
| 36 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.43257620 |
| 37 | Hypoplasia of the uterus (HP:0000013) | 2.42236156 |
| 38 | Increased IgM level (HP:0003496) | 2.42197189 |
| 39 | Congenital, generalized hypertrichosis (HP:0004540) | 2.36427161 |
| 40 | Abnormality of T cell physiology (HP:0011840) | 2.34221306 |
| 41 | Nephronophthisis (HP:0000090) | 2.33424659 |
| 42 | Partial agenesis of the corpus callosum (HP:0001338) | 2.33396031 |
| 43 | Severe muscular hypotonia (HP:0006829) | 2.32661241 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.32354976 |
| 45 | Abnormality of the renal cortex (HP:0011035) | 2.30597809 |
| 46 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.27097454 |
| 47 | Pancreatic cysts (HP:0001737) | 2.25894204 |
| 48 | Mitochondrial inheritance (HP:0001427) | 2.25841605 |
| 49 | Decreased circulating renin level (HP:0003351) | 2.24013019 |
| 50 | Acute encephalopathy (HP:0006846) | 2.23491325 |
| 51 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.21642507 |
| 52 | Abnormal drinking behavior (HP:0030082) | 2.21056020 |
| 53 | Polydipsia (HP:0001959) | 2.21056020 |
| 54 | Hyperglycinuria (HP:0003108) | 2.20138240 |
| 55 | Bulbous nose (HP:0000414) | 2.16313642 |
| 56 | Nephrogenic diabetes insipidus (HP:0009806) | 2.14108832 |
| 57 | Metabolic alkalosis (HP:0200114) | 2.12203919 |
| 58 | Increased muscle lipid content (HP:0009058) | 2.10752630 |
| 59 | Muscle fiber atrophy (HP:0100295) | 2.10345325 |
| 60 | Lower limb hyperreflexia (HP:0002395) | 2.08753536 |
| 61 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.08200769 |
| 62 | Posterior subcapsular cataract (HP:0007787) | 2.07914002 |
| 63 | Hip dysplasia (HP:0001385) | 2.04967317 |
| 64 | Myokymia (HP:0002411) | 2.04847234 |
| 65 | Increased CSF lactate (HP:0002490) | 2.03489589 |
| 66 | Cerebellar dysplasia (HP:0007033) | 2.02367435 |
| 67 | Hydroxyprolinuria (HP:0003080) | 2.02285946 |
| 68 | Abnormality of proline metabolism (HP:0010907) | 2.02285946 |
| 69 | Abnormality of the renal medulla (HP:0100957) | 2.01906328 |
| 70 | Pancreatic fibrosis (HP:0100732) | 2.01700740 |
| 71 | Cerebral palsy (HP:0100021) | 2.01645161 |
| 72 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.01315461 |
| 73 | Constricted visual fields (HP:0001133) | 1.99782283 |
| 74 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.97445257 |
| 75 | Vertebral fusion (HP:0002948) | 1.96962734 |
| 76 | Progressive macrocephaly (HP:0004481) | 1.94971098 |
| 77 | Polyuria (HP:0000103) | 1.94932695 |
| 78 | Attenuation of retinal blood vessels (HP:0007843) | 1.94575869 |
| 79 | True hermaphroditism (HP:0010459) | 1.92570231 |
| 80 | Optic disc pallor (HP:0000543) | 1.87980777 |
| 81 | Hypoproteinemia (HP:0003075) | 1.87895888 |
| 82 | Renal Fanconi syndrome (HP:0001994) | 1.87238617 |
| 83 | Tubulointerstitial fibrosis (HP:0005576) | 1.86588278 |
| 84 | Ulnar deviation of the wrist (HP:0003049) | 1.84169575 |
| 85 | Abolished electroretinogram (ERG) (HP:0000550) | 1.79308992 |
| 86 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.76323612 |
| 87 | Abnormality of the pons (HP:0007361) | 1.76225607 |
| 88 | Alkalosis (HP:0001948) | 1.73832929 |
| 89 | Abnormality of urine glucose concentration (HP:0011016) | 1.72337504 |
| 90 | Glycosuria (HP:0003076) | 1.72337504 |
| 91 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.71029383 |
| 92 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.67593603 |
| 93 | Retinal dysplasia (HP:0007973) | 1.67110578 |
| 94 | Hepatocellular necrosis (HP:0001404) | 1.61485081 |
| 95 | Hypomagnesemia (HP:0002917) | 1.60130409 |
| 96 | Gaze-evoked nystagmus (HP:0000640) | 1.60094953 |
| 97 | Congenital hepatic fibrosis (HP:0002612) | 1.57681716 |
| 98 | Abnormality of iron homeostasis (HP:0011031) | 1.57168684 |
| 99 | Pachygyria (HP:0001302) | 1.55921763 |
| 100 | Sensorimotor neuropathy (HP:0007141) | 1.55621018 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.88282294 |
| 2 | TLK1 | 4.96786135 |
| 3 | PINK1 | 4.48572626 |
| 4 | BMPR2 | 4.01876248 |
| 5 | SIK2 | 2.84931759 |
| 6 | MAP4K2 | 2.65159658 |
| 7 | SIK3 | 2.54510665 |
| 8 | ADRBK2 | 2.44606144 |
| 9 | TIE1 | 2.26870210 |
| 10 | DAPK2 | 2.18125264 |
| 11 | MAPKAPK3 | 2.17141439 |
| 12 | TAOK3 | 1.79891577 |
| 13 | FRK | 1.79810465 |
| 14 | NEK2 | 1.67687131 |
| 15 | MAP3K11 | 1.60836684 |
| 16 | GRK1 | 1.57829802 |
| 17 | MAP3K12 | 1.57672862 |
| 18 | ERBB2 | 1.51112652 |
| 19 | SIK1 | 1.50899943 |
| 20 | NUAK1 | 1.49778573 |
| 21 | MAP3K7 | 1.46028011 |
| 22 | MAPKAPK5 | 1.42716433 |
| 23 | WNK4 | 1.41894469 |
| 24 | STK11 | 1.41697670 |
| 25 | MAP3K4 | 1.36205773 |
| 26 | WNK3 | 1.29230109 |
| 27 | NME1 | 1.27733059 |
| 28 | MAPK13 | 1.23581830 |
| 29 | PHKG2 | 1.22425258 |
| 30 | PHKG1 | 1.22425258 |
| 31 | DAPK1 | 1.17893753 |
| 32 | MAP2K7 | 1.16991552 |
| 33 | ACVR1B | 1.14479944 |
| 34 | TXK | 1.14219046 |
| 35 | KIT | 1.02058643 |
| 36 | BMPR1B | 0.98583382 |
| 37 | STK16 | 0.98339723 |
| 38 | DYRK2 | 0.97993485 |
| 39 | ZAK | 0.97561644 |
| 40 | VRK2 | 0.97271946 |
| 41 | BCR | 0.95953943 |
| 42 | OXSR1 | 0.92378080 |
| 43 | SYK | 0.90977222 |
| 44 | ICK | 0.90387471 |
| 45 | MST4 | 0.87003197 |
| 46 | TEC | 0.86177134 |
| 47 | BTK | 0.85929120 |
| 48 | STK38L | 0.85554685 |
| 49 | PRKCG | 0.79374744 |
| 50 | STK3 | 0.78250326 |
| 51 | BCKDK | 0.75511770 |
| 52 | ADRBK1 | 0.72727285 |
| 53 | RPS6KA6 | 0.71688018 |
| 54 | PLK4 | 0.68745456 |
| 55 | TAF1 | 0.68078302 |
| 56 | PIK3CA | 0.67802746 |
| 57 | TRPM7 | 0.65742165 |
| 58 | CAMK1 | 0.65428462 |
| 59 | MAP2K4 | 0.64850548 |
| 60 | MARK3 | 0.63884941 |
| 61 | PRKAA2 | 0.60340928 |
| 62 | ILK | 0.56403130 |
| 63 | PRKCI | 0.55960654 |
| 64 | RPS6KA5 | 0.52881131 |
| 65 | ITK | 0.51790114 |
| 66 | PRKAA1 | 0.50912502 |
| 67 | EIF2AK1 | 0.49903823 |
| 68 | EEF2K | 0.49428740 |
| 69 | PTK2B | 0.47198490 |
| 70 | GRK5 | 0.46510312 |
| 71 | CAMK4 | 0.44887338 |
| 72 | FLT3 | 0.43847447 |
| 73 | STK38 | 0.42507076 |
| 74 | GRK7 | 0.42359126 |
| 75 | VRK1 | 0.41963447 |
| 76 | PRKCA | 0.41152735 |
| 77 | PRKCQ | 0.40501826 |
| 78 | MAP4K1 | 0.40153181 |
| 79 | PRKCE | 0.39516234 |
| 80 | CAMK2A | 0.39484933 |
| 81 | PRKCZ | 0.38880814 |
| 82 | PRKACG | 0.38611551 |
| 83 | RPS6KL1 | 0.38046350 |
| 84 | RPS6KC1 | 0.38046350 |
| 85 | CDK19 | 0.37654003 |
| 86 | INSRR | 0.37044653 |
| 87 | IGF1R | 0.34563922 |
| 88 | PAK6 | 0.31073876 |
| 89 | MAP2K6 | 0.30697117 |
| 90 | STK39 | 0.30680067 |
| 91 | TRIM28 | 0.29681778 |
| 92 | ATR | 0.28505080 |
| 93 | PRKACA | 0.28220640 |
| 94 | CSNK1G3 | 0.28111641 |
| 95 | CSNK1G2 | 0.26038480 |
| 96 | CSNK1A1 | 0.25779843 |
| 97 | WNK1 | 0.24273480 |
| 98 | MAPK4 | 0.23963283 |
| 99 | CHEK2 | 0.23808059 |
| 100 | LYN | 0.23645933 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.79132318 |
| 2 | Olfactory transduction_Homo sapiens_hsa04740 | 3.37168387 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.14944755 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.89193344 |
| 5 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.73545505 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.73054754 |
| 7 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.45932340 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.44599576 |
| 9 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.41168974 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.31231944 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.18262816 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.95479253 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.84423853 |
| 14 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.75795922 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.66299977 |
| 16 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.64826810 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.62193900 |
| 18 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.61588377 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.60301269 |
| 20 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.59841804 |
| 21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.53562610 |
| 22 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.50013725 |
| 23 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.49042093 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.36548916 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.36127581 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34607524 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.27810313 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.27657295 |
| 29 | Proteasome_Homo sapiens_hsa03050 | 1.26789995 |
| 30 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.25960840 |
| 31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.25340848 |
| 32 | RNA degradation_Homo sapiens_hsa03018 | 1.20527845 |
| 33 | Huntingtons disease_Homo sapiens_hsa05016 | 1.18372537 |
| 34 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.14216877 |
| 35 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.10537173 |
| 36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.08281242 |
| 37 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.05719217 |
| 38 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.05636144 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02251828 |
| 40 | Histidine metabolism_Homo sapiens_hsa00340 | 1.02251447 |
| 41 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.01462280 |
| 42 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.98549511 |
| 43 | Morphine addiction_Homo sapiens_hsa05032 | 0.95885001 |
| 44 | Homologous recombination_Homo sapiens_hsa03440 | 0.93765105 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.92425030 |
| 46 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.92203825 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89847363 |
| 48 | Salivary secretion_Homo sapiens_hsa04970 | 0.87944753 |
| 49 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.86488057 |
| 50 | Retinol metabolism_Homo sapiens_hsa00830 | 0.84789954 |
| 51 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.81209985 |
| 52 | Long-term depression_Homo sapiens_hsa04730 | 0.78557710 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.77014194 |
| 54 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.76724986 |
| 55 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.75522857 |
| 56 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.74917490 |
| 57 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.74854490 |
| 58 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.74653755 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72409275 |
| 60 | Nicotine addiction_Homo sapiens_hsa05033 | 0.71846458 |
| 61 | GABAergic synapse_Homo sapiens_hsa04727 | 0.68252295 |
| 62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67991475 |
| 63 | Circadian entrainment_Homo sapiens_hsa04713 | 0.67937337 |
| 64 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.66800443 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.66537885 |
| 66 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.66039263 |
| 67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.65684164 |
| 68 | Sulfur relay system_Homo sapiens_hsa04122 | 0.65093977 |
| 69 | Protein export_Homo sapiens_hsa03060 | 0.63424147 |
| 70 | RNA polymerase_Homo sapiens_hsa03020 | 0.61317943 |
| 71 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.60645833 |
| 72 | ABC transporters_Homo sapiens_hsa02010 | 0.60359667 |
| 73 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.60165272 |
| 74 | Viral myocarditis_Homo sapiens_hsa05416 | 0.58280219 |
| 75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55046989 |
| 76 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.54913911 |
| 77 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.54254444 |
| 78 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.54225170 |
| 79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.51534835 |
| 80 | Insulin secretion_Homo sapiens_hsa04911 | 0.51160233 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51088740 |
| 82 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.50816684 |
| 83 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.50647219 |
| 84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50499574 |
| 85 | Peroxisome_Homo sapiens_hsa04146 | 0.50303840 |
| 86 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.48929407 |
| 87 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.47371571 |
| 88 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.47029364 |
| 89 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46130977 |
| 90 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.45516857 |
| 91 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.43949470 |
| 92 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.42844309 |
| 93 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.41655183 |
| 94 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.41053140 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.39987152 |
| 96 | Circadian rhythm_Homo sapiens_hsa04710 | 0.39983917 |
| 97 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.39093938 |
| 98 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38933013 |
| 99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.38705692 |
| 100 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.38244312 |

