RPL9P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.09097384
2pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)5.94120062
3UMP metabolic process (GO:0046049)5.94120062
4pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)5.94120062
5UMP biosynthetic process (GO:0006222)5.94120062
6organic cation transport (GO:0015695)5.86214813
7drug transmembrane transport (GO:0006855)5.51273969
8nucleotide salvage (GO:0043173)5.40591915
9histamine transport (GO:0051608)5.26691415
10pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)5.03721904
11quaternary ammonium group transport (GO:0015697)4.79322443
12pyrimidine nucleoside monophosphate metabolic process (GO:0009129)4.76743900
13positive regulation of meiosis (GO:0045836)4.62189140
14exogenous drug catabolic process (GO:0042738)4.57909386
15viral transcription (GO:0019083)4.57661420
16pyrimidine nucleoside salvage (GO:0043097)4.54442736
17pyrimidine-containing compound salvage (GO:0008655)4.54442736
18nucleoside salvage (GO:0043174)4.50846622
19translational termination (GO:0006415)4.41217468
20positive regulation of meiotic cell cycle (GO:0051446)4.33533239
21resolution of meiotic recombination intermediates (GO:0000712)4.31971257
22detection of chemical stimulus involved in sensory perception of smell (GO:0050911)4.20518489
23translational elongation (GO:0006414)4.16282106
24neurotransmitter biosynthetic process (GO:0042136)4.12594587
25meiotic chromosome segregation (GO:0045132)4.12189617
26regulation of activation of Janus kinase activity (GO:0010533)4.07797976
27rRNA catabolic process (GO:0016075)4.07370908
28regulation of meiosis I (GO:0060631)3.98458783
29CTP metabolic process (GO:0046036)3.93830492
30CTP biosynthetic process (GO:0006241)3.93830492
31tooth mineralization (GO:0034505)3.91868327
32drug transport (GO:0015893)3.89680512
33negative regulation of epidermal cell differentiation (GO:0045605)3.86652781
34drug catabolic process (GO:0042737)3.76841628
35pentose metabolic process (GO:0019321)3.74590076
36neurotransmitter metabolic process (GO:0042133)3.69234531
37pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.66862969
38behavioral response to nicotine (GO:0035095)3.65994855
39synaptonemal complex assembly (GO:0007130)3.60614861
40reciprocal meiotic recombination (GO:0007131)3.57176378
41reciprocal DNA recombination (GO:0035825)3.57176378
42ribosomal large subunit biogenesis (GO:0042273)3.54800085
43pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.53397049
44cellular ketone body metabolic process (GO:0046950)3.48424459
45SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.44588481
46pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.37736764
47piRNA metabolic process (GO:0034587)3.37601188
48synaptonemal complex organization (GO:0070193)3.35872563
49cotranslational protein targeting to membrane (GO:0006613)3.35278036
50azole transport (GO:0045117)3.33598738
51protein targeting to ER (GO:0045047)3.31437707
52regulation of guanylate cyclase activity (GO:0031282)3.31387730
53protein localization to endoplasmic reticulum (GO:0070972)3.30197209
54tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.28370235
55RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.28370235
56cellular protein complex disassembly (GO:0043624)3.18075622
57pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.16957728
58positive regulation of guanylate cyclase activity (GO:0031284)3.14937111
59regulation of immune response to tumor cell (GO:0002837)3.14793271
60regulation of response to tumor cell (GO:0002834)3.14793271
61positive regulation of response to tumor cell (GO:0002836)3.14793271
62positive regulation of immune response to tumor cell (GO:0002839)3.14793271
63viral life cycle (GO:0019058)3.13258983
64pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.12497945
65establishment of protein localization to endoplasmic reticulum (GO:0072599)3.12194549
66phosphatidylinositol acyl-chain remodeling (GO:0036149)3.12003457
67nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.11425551
68ketone body metabolic process (GO:1902224)3.10167774
69detection of chemical stimulus involved in sensory perception (GO:0050907)3.08205000
70positive regulation of protein homodimerization activity (GO:0090073)3.07282503
71positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.05215925
72negative regulation of transcription regulatory region DNA binding (GO:2000678)3.03396528
73epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)3.01474533
74pentose-phosphate shunt (GO:0006098)3.01396118
75keratinocyte development (GO:0003334)3.00053628
76chromosome organization involved in meiosis (GO:0070192)2.96041931
77translational initiation (GO:0006413)2.94683986
78pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.93655536
79cornea development in camera-type eye (GO:0061303)2.92325576
80pyrimidine ribonucleotide metabolic process (GO:0009218)2.86297214
81activation of NF-kappaB-inducing kinase activity (GO:0007250)2.84553367
82negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.83250719
83negative regulation of telomere maintenance (GO:0032205)2.81297616
84response to nitric oxide (GO:0071731)2.80098254
85cilium or flagellum-dependent cell motility (GO:0001539)2.79410588
86pyrimidine ribonucleoside metabolic process (GO:0046131)2.78347613
87negative regulation of epidermis development (GO:0045683)2.77122893
88regulation of mesenchymal cell apoptotic process (GO:2001053)2.74743072
89carnitine transmembrane transport (GO:1902603)2.72975312
90fucose catabolic process (GO:0019317)2.71593608
91L-fucose metabolic process (GO:0042354)2.71593608
92L-fucose catabolic process (GO:0042355)2.71593608
93purine nucleotide salvage (GO:0032261)2.68666621
94maturation of SSU-rRNA (GO:0030490)2.68335703
95NADPH regeneration (GO:0006740)2.63719470
96synapsis (GO:0007129)2.62962397
97protein complex disassembly (GO:0043241)2.60229551
98negative regulation of calcium ion transport into cytosol (GO:0010523)2.59486666
99histone H3-K36 demethylation (GO:0070544)2.59256118
100RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.58906957

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.39350097
2ZNF274_21170338_ChIP-Seq_K562_Hela3.78533810
3IGF1R_20145208_ChIP-Seq_DFB_Human3.78146014
4IRF1_19129219_ChIP-ChIP_H3396_Human2.89655573
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.70556781
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.59954278
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.52402666
8VDR_22108803_ChIP-Seq_LS180_Human2.46543304
9PCGF2_27294783_Chip-Seq_NPCs_Mouse2.34474136
10PCGF2_27294783_Chip-Seq_ESCs_Mouse2.13616654
11EWS_26573619_Chip-Seq_HEK293_Human2.08085667
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.00515340
13EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.96363581
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.90929797
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.90407188
16BMI1_23680149_ChIP-Seq_NPCS_Mouse1.85300320
17TP53_22573176_ChIP-Seq_HFKS_Human1.82616907
18FUS_26573619_Chip-Seq_HEK293_Human1.82431208
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.81750536
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.81342587
21GABP_17652178_ChIP-ChIP_JURKAT_Human1.74973130
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.73381681
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.72074781
24NANOG_19829295_ChIP-Seq_ESCs_Human1.68169899
25SOX2_19829295_ChIP-Seq_ESCs_Human1.68169899
26CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68161883
27NANOG_20526341_ChIP-Seq_ESCs_Human1.61219365
28NCOR_22424771_ChIP-Seq_293T_Human1.57259778
29AUTS2_25519132_ChIP-Seq_293T-REX_Human1.55830500
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55429736
31P53_21459846_ChIP-Seq_SAOS-2_Human1.53991435
32AR_20517297_ChIP-Seq_VCAP_Human1.52312884
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.47656413
34VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.44221423
35FOXA1_25329375_ChIP-Seq_VCAP_Human1.41841418
36FOXA1_27270436_Chip-Seq_PROSTATE_Human1.41841418
37POU3F2_20337985_ChIP-ChIP_501MEL_Human1.41147086
38GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.37332770
39FOXH1_21741376_ChIP-Seq_ESCs_Human1.37245256
40FOXA1_21572438_ChIP-Seq_LNCaP_Human1.36351979
41P300_19829295_ChIP-Seq_ESCs_Human1.34310578
42BCAT_22108803_ChIP-Seq_LS180_Human1.31460426
43RNF2_27304074_Chip-Seq_NSC_Mouse1.31290970
44ERA_21632823_ChIP-Seq_H3396_Human1.28185987
45TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.24811346
46LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.23979575
47RAC3_21632823_ChIP-Seq_H3396_Human1.23943904
48CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.23049939
49E2F1_20622854_ChIP-Seq_HELA_Human1.22209397
50NOTCH1_21737748_ChIP-Seq_TLL_Human1.21096020
51ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20673858
52SMAD4_21741376_ChIP-Seq_EPCs_Human1.20105738
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.19802562
54IKZF1_21737484_ChIP-ChIP_HCT116_Human1.19309966
55GATA3_26560356_Chip-Seq_TH2_Human1.18277893
56MYC_18940864_ChIP-ChIP_HL60_Human1.18018656
57GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17479590
58PRDM14_20953172_ChIP-Seq_ESCs_Human1.15681883
59TAF2_19829295_ChIP-Seq_ESCs_Human1.14964542
60NFE2_27457419_Chip-Seq_LIVER_Mouse1.14475634
61ER_23166858_ChIP-Seq_MCF-7_Human1.13682650
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.12544710
63TAF15_26573619_Chip-Seq_HEK293_Human1.10403276
64MYC_19829295_ChIP-Seq_ESCs_Human1.09213295
65SUZ12_27294783_Chip-Seq_NPCs_Mouse1.08099365
66TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07782304
67TCF4_22108803_ChIP-Seq_LS180_Human1.07434223
68TDRD3_21172665_ChIP-Seq_MCF-7_Human1.07161898
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.06699501
70RUNX_20019798_ChIP-Seq_JUKART_Human1.06401807
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.06185175
72RUNX2_22187159_ChIP-Seq_PCA_Human1.05658193
73JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05601355
74PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.05293293
75KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04976058
76VDR_23849224_ChIP-Seq_CD4+_Human1.04710752
77SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.04407481
78SMAD3_21741376_ChIP-Seq_EPCs_Human1.04276802
79HOXB7_26014856_ChIP-Seq_BT474_Human1.04141369
80IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.03672284
81CBP_20019798_ChIP-Seq_JUKART_Human1.03252129
82IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.03252129
83TCF4_23295773_ChIP-Seq_U87_Human1.03161777
84UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02572213
85NR3C1_21868756_ChIP-Seq_MCF10A_Human1.02360165
86EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.01507258
87CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.00622490
88GBX2_23144817_ChIP-Seq_PC3_Human1.00238746
89ETS1_20019798_ChIP-Seq_JURKAT_Human0.99451092
90RBPJ_21746931_ChIP-Seq_IB4_Human0.98897974
91ETV2_25802403_ChIP-Seq_MESCs_Mouse0.98453269
92JUN_21703547_ChIP-Seq_K562_Human0.98317815
93POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.97572613
94ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.97470240
95SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.97360545
96GATA3_21878914_ChIP-Seq_MCF-7_Human0.96548673
97CRX_20693478_ChIP-Seq_RETINA_Mouse0.95685373
98CEBPB_22108803_ChIP-Seq_LS180_Human0.94455480
99RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.94382988
100GATA3_26560356_Chip-Seq_TH1_Human0.93916535

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003646_muscle_fatigue4.81383546
2MP0003806_abnormal_nucleotide_metabolis4.57301663
3MP0009379_abnormal_foot_pigmentation4.52347481
4MP0001873_stomach_inflammation3.16059636
5MP0002163_abnormal_gland_morphology2.99297655
6MP0006292_abnormal_olfactory_placode2.93273665
7MP0005360_urolithiasis2.71988369
8MP0008872_abnormal_physiological_respon2.55856195
9MP0008875_abnormal_xenobiotic_pharmacok2.39853203
10MP0002160_abnormal_reproductive_system2.18108518
11MP0000372_irregular_coat_pigmentation2.01599478
12MP0005167_abnormal_blood-brain_barrier1.96107349
13MP0005389_reproductive_system_phenotype1.95795069
14MP0001919_abnormal_reproductive_system1.94894170
15MP0002138_abnormal_hepatobiliary_system1.93153321
16MP0008877_abnormal_DNA_methylation1.91900834
17MP0002837_dystrophic_cardiac_calcinosis1.90764469
18MP0001986_abnormal_taste_sensitivity1.85055905
19MP0004043_abnormal_pH_regulation1.79237764
20MP0001664_abnormal_digestion1.76585675
21MP0002234_abnormal_pharynx_morphology1.74583545
22MP0005085_abnormal_gallbladder_physiolo1.73638075
23MP0005645_abnormal_hypothalamus_physiol1.70687925
24MP0004147_increased_porphyrin_level1.69135422
25MP0002102_abnormal_ear_morphology1.64496000
26MP0005379_endocrine/exocrine_gland_phen1.63893815
27MP0001835_abnormal_antigen_presentation1.57413056
28MP0002139_abnormal_hepatobiliary_system1.53386460
29MP0005551_abnormal_eye_electrophysiolog1.51791599
30MP0006276_abnormal_autonomic_nervous1.51652098
31MP0003718_maternal_effect1.49143343
32MP0005084_abnormal_gallbladder_morpholo1.48455036
33MP0001764_abnormal_homeostasis1.48058798
34MP0004885_abnormal_endolymph1.42687900
35MP0004145_abnormal_muscle_electrophysio1.41016344
36MP0002148_abnormal_hypersensitivity_rea1.40371724
37MP0006082_CNS_inflammation1.36807840
38MP0005075_abnormal_melanosome_morpholog1.31674563
39MP0001188_hyperpigmentation1.28737497
40MP0001663_abnormal_digestive_system1.27491836
41MP0005365_abnormal_bile_salt1.25812423
42MP0003724_increased_susceptibility_to1.24956710
43MP0000427_abnormal_hair_cycle1.24706371
44MP0003567_abnormal_fetal_cardiomyocyte1.24065373
45MP0001440_abnormal_grooming_behavior1.22546878
46MP0000049_abnormal_middle_ear1.22481537
47MP0001790_abnormal_immune_system1.22323524
48MP0005387_immune_system_phenotype1.22323524
49MP0009643_abnormal_urine_homeostasis1.19852667
50MP0010329_abnormal_lipoprotein_level1.18171109
51MP0005410_abnormal_fertilization1.08812559
52MP0001501_abnormal_sleep_pattern1.06312607
53MP0004019_abnormal_vitamin_homeostasis1.02901397
54MP0010155_abnormal_intestine_physiology1.02646455
55MP0005310_abnormal_salivary_gland0.99722561
56MP0000538_abnormal_urinary_bladder0.97886630
57MP0001968_abnormal_touch/_nociception0.97271515
58MP0001800_abnormal_humoral_immune0.94272987
59MP0005671_abnormal_response_to0.94184172
60MP0003252_abnormal_bile_duct0.93059962
61MP0000470_abnormal_stomach_morphology0.92370169
62MP0004381_abnormal_hair_follicle0.91320096
63MP0002272_abnormal_nervous_system0.91164725
64MP0002876_abnormal_thyroid_physiology0.91130343
65MP0005332_abnormal_amino_acid0.91035932
66MP0002095_abnormal_skin_pigmentation0.88812898
67MP0004142_abnormal_muscle_tone0.88600453
68MP0004484_altered_response_of0.88213288
69MP0005266_abnormal_metabolism0.88090454
70MP0003787_abnormal_imprinting0.87860534
71MP0005174_abnormal_tail_pigmentation0.86019354
72MP0001348_abnormal_lacrimal_gland0.84491850
73MP0005381_digestive/alimentary_phenotyp0.83078520
74MP0002638_abnormal_pupillary_reflex0.81810358
75MP0001666_abnormal_nutrient_absorption0.81161425
76MP0003195_calcinosis0.81090857
77MP0008775_abnormal_heart_ventricle0.81029110
78MP0002210_abnormal_sex_determination0.80874982
79MP0004742_abnormal_vestibular_system0.74704645
80MP0003011_delayed_dark_adaptation0.73644061
81MP0009764_decreased_sensitivity_to0.73282824
82MP0001293_anophthalmia0.72198428
83MP0009745_abnormal_behavioral_response0.71981473
84MP0002723_abnormal_immune_serum0.71600884
85MP0001756_abnormal_urination0.69717747
86MP0008058_abnormal_DNA_repair0.69506910
87MP0003045_fibrosis0.68912478
88MP0009333_abnormal_splenocyte_physiolog0.68566567
89MP0001963_abnormal_hearing_physiology0.68253396
90MP0008995_early_reproductive_senescence0.67443677
91MP0000230_abnormal_systemic_arterial0.67382075
92MP0003183_abnormal_peptide_metabolism0.67150817
93MP0001819_abnormal_immune_cell0.66174870
94MP0001485_abnormal_pinna_reflex0.66106969
95MP0002420_abnormal_adaptive_immunity0.65856170
96MP0000678_abnormal_parathyroid_gland0.65069006
97MP0002735_abnormal_chemical_nociception0.64276583
98MP0003866_abnormal_defecation0.63954418
99MP0003786_premature_aging0.63477859
100MP0003698_abnormal_male_reproductive0.62593942

Predicted human phenotypes

RankGene SetZ-score
1Hypoplasia of the fovea (HP:0007750)4.36337209
2Aplasia/Hypoplasia of the fovea (HP:0008060)4.36337209
3Unilateral renal agenesis (HP:0000122)4.08989117
4Bilateral microphthalmos (HP:0007633)3.98092953
5Congenital stationary night blindness (HP:0007642)3.86111060
6Hip dysplasia (HP:0001385)3.66888559
7Abnormality of the fovea (HP:0000493)3.48433363
8Molar tooth sign on MRI (HP:0002419)3.35963183
9Abnormality of midbrain morphology (HP:0002418)3.35963183
10Absent rod-and cone-mediated responses on ERG (HP:0007688)3.23470490
11Abnormality of cells of the erythroid lineage (HP:0012130)3.10467674
12Conjugated hyperbilirubinemia (HP:0002908)3.09434239
133-Methylglutaconic aciduria (HP:0003535)3.02793726
14Pancreatic cysts (HP:0001737)2.84869610
15True hermaphroditism (HP:0010459)2.81760466
16Abnormal delayed hypersensitivity skin test (HP:0002963)2.78701810
17Reticulocytopenia (HP:0001896)2.77020791
18Abnormality of the pons (HP:0007361)2.75572095
19Hypoplasia of the pons (HP:0012110)2.72355490
20Abnormal number of erythroid precursors (HP:0012131)2.71129001
21Bile duct proliferation (HP:0001408)2.70184870
22Abnormal biliary tract physiology (HP:0012439)2.70184870
23Hypoplasia of the uterus (HP:0000013)2.70168154
24Abnormality of glycine metabolism (HP:0010895)2.70049210
25Abnormality of serine family amino acid metabolism (HP:0010894)2.70049210
26Aplasia/Hypoplasia of the macula (HP:0008059)2.69839230
27Hyperglycinuria (HP:0003108)2.65160453
28Hyperglycinemia (HP:0002154)2.64633684
29Fused cervical vertebrae (HP:0002949)2.56233496
30Panhypogammaglobulinemia (HP:0003139)2.55961428
31Aplasia/Hypoplasia affecting the retina (HP:0008061)2.53120707
32Abnormal rod and cone electroretinograms (HP:0008323)2.48431505
33Decreased electroretinogram (ERG) amplitude (HP:0000654)2.48326721
34Constricted visual fields (HP:0001133)2.45484021
35Pancreatic fibrosis (HP:0100732)2.45333317
36Posterior subcapsular cataract (HP:0007787)2.43755749
37Progressive inability to walk (HP:0002505)2.42322685
38Abnormality of the renal cortex (HP:0011035)2.41331867
39Decreased central vision (HP:0007663)2.40950213
40Aplasia cutis congenita (HP:0001057)2.39610563
41Confusion (HP:0001289)2.39223541
42Decreased circulating renin level (HP:0003351)2.38835520
43Abolished electroretinogram (ERG) (HP:0000550)2.37431715
44Abnormality of glutamine family amino acid metabolism (HP:0010902)2.35584835
45Tubular atrophy (HP:0000092)2.33389495
46Abnormality of the renal collecting system (HP:0004742)2.28609719
47Metabolic alkalosis (HP:0200114)2.28074566
48Concave nail (HP:0001598)2.25057342
49Tachypnea (HP:0002789)2.24907016
50Widely patent fontanelles and sutures (HP:0004492)2.21369036
51Aplasia/Hypoplasia of the spleen (HP:0010451)2.20818015
52Abnormality of B cell number (HP:0010975)2.20653853
53Mixed hearing impairment (HP:0000410)2.19929928
54Nephronophthisis (HP:0000090)2.19467275
55Asplenia (HP:0001746)2.18372107
56Tetraplegia (HP:0002445)2.14769789
57Abnormality of urine glucose concentration (HP:0011016)2.14295549
58Glycosuria (HP:0003076)2.14295549
59Attenuation of retinal blood vessels (HP:0007843)2.13825200
60Opisthotonus (HP:0002179)2.12475838
61Lipid accumulation in hepatocytes (HP:0006561)2.08125075
62Inability to walk (HP:0002540)2.06947704
63Macrocytic anemia (HP:0001972)2.05257131
64Abnormality of DNA repair (HP:0003254)2.04342805
65Abnormality of the right ventricle (HP:0001707)2.02579219
66Abnormality of the renal medulla (HP:0100957)2.00246864
67Aplasia/hypoplasia of the uterus (HP:0008684)1.95100713
68Central scotoma (HP:0000603)1.92658231
69Male pseudohermaphroditism (HP:0000037)1.92486099
70Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.92213911
71Type II lissencephaly (HP:0007260)1.91524402
72B lymphocytopenia (HP:0010976)1.90888980
73Bulbous nose (HP:0000414)1.90472642
74Triphalangeal thumb (HP:0001199)1.90305434
75Increased hepatocellular lipid droplets (HP:0006565)1.90019157
76Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.88687732
77Abnormal protein N-linked glycosylation (HP:0012347)1.88687732
78Abnormal protein glycosylation (HP:0012346)1.88687732
79Abnormal glycosylation (HP:0012345)1.88687732
80Autoimmune thrombocytopenia (HP:0001973)1.88057564
81Dyskinesia (HP:0100660)1.86188224
82Pallor (HP:0000980)1.85229580
83Abnormality of transition element cation homeostasis (HP:0011030)1.84950295
84Abnormality of macular pigmentation (HP:0008002)1.84428775
85Respiratory difficulties (HP:0002880)1.82204437
86Conical tooth (HP:0000698)1.81879126
87Lissencephaly (HP:0001339)1.81877303
88Reduced antithrombin III activity (HP:0001976)1.80236028
89Stomatitis (HP:0010280)1.78311639
90CNS hypomyelination (HP:0003429)1.76774322
91Alkalosis (HP:0001948)1.76564306
92Abnormal drinking behavior (HP:0030082)1.75753553
93Polydipsia (HP:0001959)1.75753553
94Cystic liver disease (HP:0006706)1.72503577
95Increased CSF lactate (HP:0002490)1.71527740
96Acute necrotizing encephalopathy (HP:0006965)1.71519369
97Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.71234152
98Optic disc pallor (HP:0000543)1.70108413
99IgG deficiency (HP:0004315)1.68045677
100Facial hemangioma (HP:0000329)1.67415987

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK44.47347667
2BMPR23.26566720
3NUAK13.11579242
4TLK13.04577131
5ADRBK23.02462836
6INSRR2.72715825
7PINK12.72337140
8TAOK32.50045419
9VRK22.47393283
10ACVR1B2.45634408
11CDK192.39921197
12GRK12.37885235
13TAF12.34561896
14TIE12.27644204
15MAP4K12.18847461
16TXK2.03700522
17MAP4K21.99544086
18PBK1.85823309
19LIMK11.84382141
20SIK31.75545144
21RPS6KB21.73610186
22BMPR1B1.60847708
23ZAK1.52875825
24NEK21.48948730
25FRK1.48916598
26SIK21.48125645
27MAPKAPK51.46679318
28TEC1.41815513
29OXSR11.16166037
30DAPK21.10261507
31VRK11.05217591
32SYK1.04481043
33WNK41.02214327
34RPS6KA60.98379586
35STK30.97539105
36BTK0.94503095
37WNK30.94173775
38MATK0.93982077
39PASK0.91192745
40STK38L0.90020103
41MARK30.90013384
42BCKDK0.88863944
43FLT30.85683946
44KIT0.85057976
45PIK3CA0.85055946
46ERBB20.84557984
47MAP2K60.81831883
48STK110.81694167
49TGFBR10.80965502
50ITK0.80679400
51PRKCG0.79692079
52ADRBK10.77369771
53MAP3K110.76818152
54RPS6KC10.76463883
55RPS6KL10.76463883
56DYRK20.73210497
57STK390.71863028
58NME10.71156816
59MAP3K70.69913753
60PRKCQ0.68874345
61IKBKB0.65929365
62STK160.63547149
63PRKCE0.58906232
64MAPK130.58083737
65EIF2AK30.56946311
66MAP2K20.55691602
67PRKCA0.55416027
68DAPK10.55266043
69GRK50.50967680
70NLK0.50259272
71JAK30.49186494
72MKNK10.47669545
73PRKD30.44963004
74IGF1R0.44871545
75SMG10.44682089
76PRKAA20.44106092
77RPS6KB10.43324588
78MAP3K40.42989812
79LCK0.42818720
80MAPK40.42710661
81PLK20.42287441
82MUSK0.41997328
83PLK40.41724965
84LATS10.41695919
85MELK0.40250362
86CSNK2A10.39903613
87MAPKAPK30.39204130
88MYLK0.37524285
89CSNK2A20.37097789
90PLK10.36754837
91DYRK1A0.36597618
92PRKACG0.36548479
93LYN0.35843836
94PRKACA0.34117378
95TRIM280.32521975
96TNIK0.32406784
97RPS6KA50.31262771
98CSNK1A10.30416411
99CHEK20.30308348
100PRKCD0.30184094

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.90648194
2Sulfur relay system_Homo sapiens_hsa041223.08305547
3Olfactory transduction_Homo sapiens_hsa047402.91330236
4Linoleic acid metabolism_Homo sapiens_hsa005912.79090767
5Fat digestion and absorption_Homo sapiens_hsa049752.44343063
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.44071894
7Butanoate metabolism_Homo sapiens_hsa006502.37391467
8alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.34349484
9Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26821011
10Asthma_Homo sapiens_hsa053102.14600355
11Caffeine metabolism_Homo sapiens_hsa002322.07637870
12Allograft rejection_Homo sapiens_hsa053302.00904557
13Primary immunodeficiency_Homo sapiens_hsa053401.97865802
14Vitamin digestion and absorption_Homo sapiens_hsa049771.91996077
15Drug metabolism - other enzymes_Homo sapiens_hsa009831.87244460
16Arachidonic acid metabolism_Homo sapiens_hsa005901.79567534
17Pentose phosphate pathway_Homo sapiens_hsa000301.75347941
18Autoimmune thyroid disease_Homo sapiens_hsa053201.68388423
19Retinol metabolism_Homo sapiens_hsa008301.60238513
20Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.59352702
21Chemical carcinogenesis_Homo sapiens_hsa052041.57594604
22Pyrimidine metabolism_Homo sapiens_hsa002401.51569353
23Phototransduction_Homo sapiens_hsa047441.46851407
24Tryptophan metabolism_Homo sapiens_hsa003801.44320314
25Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.44205484
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.37732494
27Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.37335581
28Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.35884600
29Ether lipid metabolism_Homo sapiens_hsa005651.33805709
30Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.29146057
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.28744671
32Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.26465393
33Graft-versus-host disease_Homo sapiens_hsa053321.25184789
34Glycerolipid metabolism_Homo sapiens_hsa005611.21861013
35Type I diabetes mellitus_Homo sapiens_hsa049401.21711310
36Nitrogen metabolism_Homo sapiens_hsa009101.19741369
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.18180869
38Propanoate metabolism_Homo sapiens_hsa006401.17920731
39Peroxisome_Homo sapiens_hsa041461.16585029
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.11504343
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.10978860
42African trypanosomiasis_Homo sapiens_hsa051431.10877132
43Selenocompound metabolism_Homo sapiens_hsa004501.09064833
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08916390
45Fanconi anemia pathway_Homo sapiens_hsa034601.08329803
46RNA degradation_Homo sapiens_hsa030181.07906800
47Arginine and proline metabolism_Homo sapiens_hsa003301.05899592
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.05153657
49Fatty acid elongation_Homo sapiens_hsa000621.02455942
50Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.99544920
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98378891
52Hematopoietic cell lineage_Homo sapiens_hsa046400.97484391
53Sulfur metabolism_Homo sapiens_hsa009200.95165044
54Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.88620177
55beta-Alanine metabolism_Homo sapiens_hsa004100.88348900
56RNA polymerase_Homo sapiens_hsa030200.87819460
57Histidine metabolism_Homo sapiens_hsa003400.84966579
58Salivary secretion_Homo sapiens_hsa049700.82964306
59Oxidative phosphorylation_Homo sapiens_hsa001900.76833483
60ABC transporters_Homo sapiens_hsa020100.74701763
61Taste transduction_Homo sapiens_hsa047420.74631842
62Fatty acid biosynthesis_Homo sapiens_hsa000610.74537598
63Basal transcription factors_Homo sapiens_hsa030220.73252219
64Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70305542
65Cyanoamino acid metabolism_Homo sapiens_hsa004600.67688636
66Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67452312
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66247796
68Homologous recombination_Homo sapiens_hsa034400.65720881
69Purine metabolism_Homo sapiens_hsa002300.65117879
70Metabolic pathways_Homo sapiens_hsa011000.64905060
71Mineral absorption_Homo sapiens_hsa049780.63503197
72Long-term depression_Homo sapiens_hsa047300.63357310
73Pancreatic secretion_Homo sapiens_hsa049720.60363757
74Fatty acid degradation_Homo sapiens_hsa000710.58728740
75Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52500329
76Starch and sucrose metabolism_Homo sapiens_hsa005000.52230515
77Serotonergic synapse_Homo sapiens_hsa047260.50256377
78Ovarian steroidogenesis_Homo sapiens_hsa049130.50195439
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.49491845
80Glutathione metabolism_Homo sapiens_hsa004800.48686637
81Insulin secretion_Homo sapiens_hsa049110.48151540
82Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47203218
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.47143261
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47002189
85Gastric acid secretion_Homo sapiens_hsa049710.46300044
86Arginine biosynthesis_Homo sapiens_hsa002200.46081188
87Glycerophospholipid metabolism_Homo sapiens_hsa005640.46032356
88Cysteine and methionine metabolism_Homo sapiens_hsa002700.45636876
89Nicotine addiction_Homo sapiens_hsa050330.44083407
90Base excision repair_Homo sapiens_hsa034100.43482816
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41886932
92Calcium signaling pathway_Homo sapiens_hsa040200.41647033
93Protein digestion and absorption_Homo sapiens_hsa049740.41510709
94Parkinsons disease_Homo sapiens_hsa050120.41105638
95Vascular smooth muscle contraction_Homo sapiens_hsa042700.38147932
96Cardiac muscle contraction_Homo sapiens_hsa042600.37362990
97Renin-angiotensin system_Homo sapiens_hsa046140.36670458
98N-Glycan biosynthesis_Homo sapiens_hsa005100.36329888
99Morphine addiction_Homo sapiens_hsa050320.36261596
100Alzheimers disease_Homo sapiens_hsa050100.34329115

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »