

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.27206089 |
| 2 | DNA deamination (GO:0045006) | 5.99863067 |
| 3 | ribosomal small subunit biogenesis (GO:0042274) | 5.20506738 |
| 4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.10472314 |
| 5 | viral transcription (GO:0019083) | 4.70110586 |
| 6 | cytidine deamination (GO:0009972) | 4.67893077 |
| 7 | cytidine metabolic process (GO:0046087) | 4.67893077 |
| 8 | cytidine catabolic process (GO:0006216) | 4.67893077 |
| 9 | proteasome assembly (GO:0043248) | 4.54783710 |
| 10 | translational termination (GO:0006415) | 4.48169637 |
| 11 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.46069646 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.39134944 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.39134944 |
| 14 | ncRNA 3-end processing (GO:0043628) | 4.30747495 |
| 15 | * translational elongation (GO:0006414) | 4.06548277 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.03922328 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.01487445 |
| 18 | cotranslational protein targeting to membrane (GO:0006613) | 3.95722488 |
| 19 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.93534356 |
| 20 | protein targeting to ER (GO:0045047) | 3.93480931 |
| 21 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.87005191 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 3.86385141 |
| 23 | maturation of SSU-rRNA (GO:0030490) | 3.79864507 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.79114465 |
| 25 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.74259454 |
| 26 | protein localization to endoplasmic reticulum (GO:0070972) | 3.74185323 |
| 27 | platelet dense granule organization (GO:0060155) | 3.69368453 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.67538990 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.67538990 |
| 30 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.57640430 |
| 31 | protein neddylation (GO:0045116) | 3.52938669 |
| 32 | viral life cycle (GO:0019058) | 3.43233784 |
| 33 | protein complex biogenesis (GO:0070271) | 3.42673328 |
| 34 | DNA strand renaturation (GO:0000733) | 3.41246201 |
| 35 | rRNA modification (GO:0000154) | 3.37912653 |
| 36 | respiratory electron transport chain (GO:0022904) | 3.35842803 |
| 37 | electron transport chain (GO:0022900) | 3.34652218 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.34172945 |
| 39 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.34172945 |
| 40 | NADH dehydrogenase complex assembly (GO:0010257) | 3.34172945 |
| 41 | positive regulation of B cell differentiation (GO:0045579) | 3.32612432 |
| 42 | chaperone-mediated protein transport (GO:0072321) | 3.30562230 |
| 43 | cellular protein complex disassembly (GO:0043624) | 3.29234329 |
| 44 | translation (GO:0006412) | 3.21901736 |
| 45 | translational initiation (GO:0006413) | 3.21660338 |
| 46 | pseudouridine synthesis (GO:0001522) | 3.21434193 |
| 47 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.13397391 |
| 48 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.08104108 |
| 49 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.06181016 |
| 50 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.99209595 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.97855784 |
| 52 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.96829605 |
| 53 | purine nucleotide salvage (GO:0032261) | 2.96781838 |
| 54 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.94687783 |
| 55 | GTP biosynthetic process (GO:0006183) | 2.93457424 |
| 56 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.90521912 |
| 57 | * cellular component biogenesis (GO:0044085) | 2.90484067 |
| 58 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.87398332 |
| 59 | rRNA processing (GO:0006364) | 2.85732896 |
| 60 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.85593158 |
| 61 | * ribonucleoprotein complex biogenesis (GO:0022613) | 2.84082049 |
| 62 | regulation of regulatory T cell differentiation (GO:0045589) | 2.82603658 |
| 63 | rRNA metabolic process (GO:0016072) | 2.78965239 |
| 64 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.77703896 |
| 65 | respiratory chain complex IV assembly (GO:0008535) | 2.77419884 |
| 66 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.76011980 |
| 67 | positive regulation of prostaglandin secretion (GO:0032308) | 2.73642212 |
| 68 | adaptation of signaling pathway (GO:0023058) | 2.73512446 |
| 69 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.72747417 |
| 70 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.72719562 |
| 71 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.71998017 |
| 72 | rRNA methylation (GO:0031167) | 2.71114006 |
| 73 | cytochrome complex assembly (GO:0017004) | 2.66938104 |
| 74 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.65727168 |
| 75 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.65727168 |
| 76 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.65727168 |
| 77 | ATP biosynthetic process (GO:0006754) | 2.65221363 |
| 78 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.63328292 |
| 79 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.63328292 |
| 80 | purine-containing compound salvage (GO:0043101) | 2.62460607 |
| 81 | mannosylation (GO:0097502) | 2.62388880 |
| 82 | protein complex disassembly (GO:0043241) | 2.61898941 |
| 83 | termination of RNA polymerase III transcription (GO:0006386) | 2.61205082 |
| 84 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.61205082 |
| 85 | actin nucleation (GO:0045010) | 2.59859982 |
| 86 | T cell migration (GO:0072678) | 2.59590979 |
| 87 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.59199669 |
| 88 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.58107002 |
| 89 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.57645581 |
| 90 | piRNA metabolic process (GO:0034587) | 2.56638589 |
| 91 | male meiosis I (GO:0007141) | 2.56059204 |
| 92 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.51636174 |
| 93 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.50904849 |
| 94 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.50904849 |
| 95 | protein-cofactor linkage (GO:0018065) | 2.50794123 |
| 96 | iron-sulfur cluster assembly (GO:0016226) | 2.50672638 |
| 97 | metallo-sulfur cluster assembly (GO:0031163) | 2.50672638 |
| 98 | CTP biosynthetic process (GO:0006241) | 2.50156799 |
| 99 | CTP metabolic process (GO:0046036) | 2.50156799 |
| 100 | deoxyribonucleotide catabolic process (GO:0009264) | 2.49911691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.56836053 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.77301127 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.88858457 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.61505344 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.56282520 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.01841164 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.89954447 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.85228580 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.74507450 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.73955410 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.62076466 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.59612297 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.55047573 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.51621635 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.46208755 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38934876 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.30173002 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.19966659 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.12665896 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.05682425 |
| 21 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.04403516 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.96304957 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.90600143 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.75788035 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.75212287 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73857217 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.70803823 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.63324970 |
| 29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.58953201 |
| 30 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.51439651 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.51031342 |
| 32 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.50749180 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50531029 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.49811489 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.45945418 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45906560 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43985404 |
| 38 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.39837116 |
| 39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39209335 |
| 40 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.35097192 |
| 41 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.33703810 |
| 42 | NCOR_22424771_ChIP-Seq_293T_Human | 1.33682061 |
| 43 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29918416 |
| 44 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.28736214 |
| 45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.27429534 |
| 46 | MYB_26560356_Chip-Seq_TH2_Human | 1.26974022 |
| 47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25966677 |
| 48 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.23204215 |
| 49 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20280725 |
| 50 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.19823431 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.19397043 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.19030311 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.19030311 |
| 54 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.15630463 |
| 55 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15234584 |
| 56 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.14655875 |
| 57 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.14279522 |
| 58 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13871648 |
| 59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12826842 |
| 60 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.10893610 |
| 61 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.10736923 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10127951 |
| 63 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.09674129 |
| 64 | GATA3_26560356_Chip-Seq_TH2_Human | 1.09479933 |
| 65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.08889642 |
| 66 | ERA_21632823_ChIP-Seq_H3396_Human | 1.07159532 |
| 67 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.06085916 |
| 68 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.06017501 |
| 69 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.05822461 |
| 70 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.04277173 |
| 71 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04037897 |
| 72 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03255197 |
| 73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02487074 |
| 74 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01648478 |
| 75 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.01055213 |
| 76 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.00543562 |
| 77 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.00070724 |
| 78 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99710471 |
| 79 | P300_27268052_Chip-Seq_Bcells_Human | 0.99503358 |
| 80 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.99214208 |
| 81 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.98883715 |
| 82 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.98545221 |
| 83 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96432636 |
| 84 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95970123 |
| 85 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.95917205 |
| 86 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.95273929 |
| 87 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.94166383 |
| 88 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93747629 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.93709353 |
| 90 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.93363418 |
| 91 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92900198 |
| 92 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.92479239 |
| 93 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91844000 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.91526740 |
| 95 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.90359499 |
| 96 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.89956722 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.89888888 |
| 98 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.89883972 |
| 99 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.89883972 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89213494 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.01312466 |
| 2 | MP0002102_abnormal_ear_morphology | 3.32322713 |
| 3 | MP0003646_muscle_fatigue | 3.10284591 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.09064083 |
| 5 | MP0001873_stomach_inflammation | 2.74535792 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.74522065 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.72417060 |
| 8 | MP0005645_abnormal_hypothalamus_physiol | 2.66806778 |
| 9 | MP0005377_hearing/vestibular/ear_phenot | 2.32032387 |
| 10 | MP0003878_abnormal_ear_physiology | 2.32032387 |
| 11 | MP0008872_abnormal_physiological_respon | 2.20440330 |
| 12 | MP0002166_altered_tumor_susceptibility | 2.18322597 |
| 13 | MP0005646_abnormal_pituitary_gland | 2.01193789 |
| 14 | MP0004147_increased_porphyrin_level | 1.96119554 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 1.93415955 |
| 16 | MP0000685_abnormal_immune_system | 1.90307133 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.89364670 |
| 18 | MP0002006_tumorigenesis | 1.84051957 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.77292442 |
| 20 | MP0009785_altered_susceptibility_to | 1.76523475 |
| 21 | MP0008877_abnormal_DNA_methylation | 1.76305898 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.70781111 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.66834379 |
| 24 | MP0002163_abnormal_gland_morphology | 1.64895564 |
| 25 | MP0006082_CNS_inflammation | 1.61753183 |
| 26 | MP0008995_early_reproductive_senescence | 1.56438001 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.55533303 |
| 28 | MP0005389_reproductive_system_phenotype | 1.55291967 |
| 29 | MP0002876_abnormal_thyroid_physiology | 1.54185641 |
| 30 | MP0003763_abnormal_thymus_physiology | 1.53113864 |
| 31 | MP0008058_abnormal_DNA_repair | 1.51969630 |
| 32 | MP0001800_abnormal_humoral_immune | 1.50642079 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.50606873 |
| 34 | MP0002736_abnormal_nociception_after | 1.45307012 |
| 35 | MP0002160_abnormal_reproductive_system | 1.44816081 |
| 36 | MP0002234_abnormal_pharynx_morphology | 1.44460206 |
| 37 | MP0005084_abnormal_gallbladder_morpholo | 1.42058821 |
| 38 | MP0001905_abnormal_dopamine_level | 1.40778724 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.39906325 |
| 40 | MP0004145_abnormal_muscle_electrophysio | 1.38613959 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.35677149 |
| 42 | MP0005360_urolithiasis | 1.32241168 |
| 43 | MP0003786_premature_aging | 1.31523402 |
| 44 | MP0001764_abnormal_homeostasis | 1.31468940 |
| 45 | MP0001919_abnormal_reproductive_system | 1.31178121 |
| 46 | MP0003718_maternal_effect | 1.29069957 |
| 47 | MP0002933_joint_inflammation | 1.28952427 |
| 48 | MP0001790_abnormal_immune_system | 1.28884093 |
| 49 | MP0005387_immune_system_phenotype | 1.28884093 |
| 50 | MP0005000_abnormal_immune_tolerance | 1.27748828 |
| 51 | MP0002420_abnormal_adaptive_immunity | 1.27671416 |
| 52 | MP0003879_abnormal_hair_cell | 1.27069726 |
| 53 | MP0008789_abnormal_olfactory_epithelium | 1.24890887 |
| 54 | MP0001819_abnormal_immune_cell | 1.22918570 |
| 55 | MP0002723_abnormal_immune_serum | 1.20773058 |
| 56 | MP0004142_abnormal_muscle_tone | 1.17768584 |
| 57 | MP0003693_abnormal_embryo_hatching | 1.16527336 |
| 58 | MP0003866_abnormal_defecation | 1.13945831 |
| 59 | MP0002095_abnormal_skin_pigmentation | 1.11714625 |
| 60 | MP0005025_abnormal_response_to | 1.10907651 |
| 61 | MP0004885_abnormal_endolymph | 1.10905429 |
| 62 | MP0001485_abnormal_pinna_reflex | 1.10811530 |
| 63 | MP0003806_abnormal_nucleotide_metabolis | 1.05944272 |
| 64 | MP0002398_abnormal_bone_marrow | 1.05028786 |
| 65 | MP0002277_abnormal_respiratory_mucosa | 1.04375364 |
| 66 | MP0002138_abnormal_hepatobiliary_system | 1.03223319 |
| 67 | MP0002452_abnormal_antigen_presenting | 1.02366487 |
| 68 | MP0009764_decreased_sensitivity_to | 1.01659460 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 1.00296297 |
| 70 | MP0000716_abnormal_immune_system | 0.99624729 |
| 71 | MP0000689_abnormal_spleen_morphology | 0.99499825 |
| 72 | MP0005636_abnormal_mineral_homeostasis | 0.98771759 |
| 73 | MP0003195_calcinosis | 0.97542381 |
| 74 | MP0000703_abnormal_thymus_morphology | 0.95720597 |
| 75 | MP0001119_abnormal_female_reproductive | 0.95495775 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.93753887 |
| 77 | MP0005410_abnormal_fertilization | 0.93341207 |
| 78 | MP0001986_abnormal_taste_sensitivity | 0.92592010 |
| 79 | MP0010155_abnormal_intestine_physiology | 0.88294453 |
| 80 | MP0002722_abnormal_immune_system | 0.87527059 |
| 81 | MP0001845_abnormal_inflammatory_respons | 0.86520086 |
| 82 | MP0002405_respiratory_system_inflammati | 0.85429395 |
| 83 | MP0002210_abnormal_sex_determination | 0.85404743 |
| 84 | MP0001663_abnormal_digestive_system | 0.83716585 |
| 85 | MP0002429_abnormal_blood_cell | 0.81848346 |
| 86 | MP0006036_abnormal_mitochondrial_physio | 0.81662881 |
| 87 | MP0000566_synostosis | 0.81557750 |
| 88 | MP0005253_abnormal_eye_physiology | 0.81414850 |
| 89 | MP0001664_abnormal_digestion | 0.80648463 |
| 90 | MP0006276_abnormal_autonomic_nervous | 0.80335637 |
| 91 | MP0004043_abnormal_pH_regulation | 0.79277934 |
| 92 | MP0005332_abnormal_amino_acid | 0.77509800 |
| 93 | MP0005085_abnormal_gallbladder_physiolo | 0.76872970 |
| 94 | MP0003186_abnormal_redox_activity | 0.76061459 |
| 95 | MP0000049_abnormal_middle_ear | 0.75949832 |
| 96 | MP0004742_abnormal_vestibular_system | 0.73910559 |
| 97 | MP0005464_abnormal_platelet_physiology | 0.71308985 |
| 98 | MP0005174_abnormal_tail_pigmentation | 0.71000218 |
| 99 | MP0001929_abnormal_gametogenesis | 0.69388872 |
| 100 | MP0009643_abnormal_urine_homeostasis | 0.68993839 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.33073575 |
| 2 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.82250545 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.73896169 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.65498952 |
| 5 | Aplastic anemia (HP:0001915) | 3.58865312 |
| 6 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.57188047 |
| 7 | Congenital stationary night blindness (HP:0007642) | 3.42126027 |
| 8 | Constricted visual fields (HP:0001133) | 3.41171645 |
| 9 | Reticulocytopenia (HP:0001896) | 3.31586539 |
| 10 | Acute encephalopathy (HP:0006846) | 3.30204328 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.29489886 |
| 12 | Abnormality of macular pigmentation (HP:0008002) | 3.29063123 |
| 13 | Increased CSF lactate (HP:0002490) | 3.17453380 |
| 14 | IgG deficiency (HP:0004315) | 3.12947482 |
| 15 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.08561653 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.05996128 |
| 17 | Hypoproteinemia (HP:0003075) | 3.05299257 |
| 18 | Hepatocellular necrosis (HP:0001404) | 2.99874073 |
| 19 | Attenuation of retinal blood vessels (HP:0007843) | 2.99331233 |
| 20 | Increased IgM level (HP:0003496) | 2.96343100 |
| 21 | Chronic otitis media (HP:0000389) | 2.93223770 |
| 22 | Muscle fiber atrophy (HP:0100295) | 2.89989194 |
| 23 | Hepatic necrosis (HP:0002605) | 2.88603618 |
| 24 | Increased hepatocellular lipid droplets (HP:0006565) | 2.87936154 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 2.80774899 |
| 26 | Chronic sinusitis (HP:0011109) | 2.79531238 |
| 27 | Severe combined immunodeficiency (HP:0004430) | 2.71748027 |
| 28 | Optic disc pallor (HP:0000543) | 2.71614547 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.71153485 |
| 30 | Abolished electroretinogram (ERG) (HP:0000550) | 2.70544197 |
| 31 | Abnormal number of erythroid precursors (HP:0012131) | 2.69462297 |
| 32 | Abnormality of B cell number (HP:0010975) | 2.65363085 |
| 33 | Cerebral edema (HP:0002181) | 2.61467795 |
| 34 | 3-Methylglutaconic aciduria (HP:0003535) | 2.59750223 |
| 35 | Pancreatic cysts (HP:0001737) | 2.59011171 |
| 36 | Lipid accumulation in hepatocytes (HP:0006561) | 2.52263741 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.46103965 |
| 38 | B lymphocytopenia (HP:0010976) | 2.42202672 |
| 39 | Lactic acidosis (HP:0003128) | 2.34683761 |
| 40 | Severe visual impairment (HP:0001141) | 2.31188989 |
| 41 | Absent thumb (HP:0009777) | 2.31085530 |
| 42 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.30807042 |
| 43 | Generalized aminoaciduria (HP:0002909) | 2.30252895 |
| 44 | True hermaphroditism (HP:0010459) | 2.29093186 |
| 45 | Methylmalonic acidemia (HP:0002912) | 2.27550865 |
| 46 | Increased serum lactate (HP:0002151) | 2.27288429 |
| 47 | Hypoplasia of the uterus (HP:0000013) | 2.26890293 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.26482936 |
| 49 | Large eyes (HP:0001090) | 2.26259777 |
| 50 | Asplenia (HP:0001746) | 2.25711651 |
| 51 | Decreased central vision (HP:0007663) | 2.25552908 |
| 52 | Macrocytic anemia (HP:0001972) | 2.24328147 |
| 53 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.24147134 |
| 54 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.24147134 |
| 55 | Abnormality of midbrain morphology (HP:0002418) | 2.23765060 |
| 56 | Molar tooth sign on MRI (HP:0002419) | 2.23765060 |
| 57 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.23607932 |
| 58 | Respiratory difficulties (HP:0002880) | 2.22434759 |
| 59 | Pancytopenia (HP:0001876) | 2.18132124 |
| 60 | Thyroiditis (HP:0100646) | 2.15987497 |
| 61 | Lethargy (HP:0001254) | 2.15898836 |
| 62 | Autoimmune thrombocytopenia (HP:0001973) | 2.15035195 |
| 63 | Methylmalonic aciduria (HP:0012120) | 2.12635406 |
| 64 | Exertional dyspnea (HP:0002875) | 2.11279738 |
| 65 | Autoimmune hemolytic anemia (HP:0001890) | 2.09571518 |
| 66 | Abnormality of alanine metabolism (HP:0010916) | 2.08416240 |
| 67 | Hyperalaninemia (HP:0003348) | 2.08416240 |
| 68 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.08416240 |
| 69 | Hyperglycinemia (HP:0002154) | 2.07962129 |
| 70 | Pallor (HP:0000980) | 2.06602434 |
| 71 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.06215586 |
| 72 | Renal cortical cysts (HP:0000803) | 2.05820844 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 2.03360765 |
| 74 | Glycosuria (HP:0003076) | 2.03360765 |
| 75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.02462982 |
| 76 | Dicarboxylic aciduria (HP:0003215) | 2.02462982 |
| 77 | Pendular nystagmus (HP:0012043) | 2.01919678 |
| 78 | Combined immunodeficiency (HP:0005387) | 2.00465992 |
| 79 | Abnormality of the renal cortex (HP:0011035) | 1.95537250 |
| 80 | Increased muscle lipid content (HP:0009058) | 1.93489065 |
| 81 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.92096365 |
| 82 | Panhypogammaglobulinemia (HP:0003139) | 1.91653754 |
| 83 | Abnormality of T cell number (HP:0011839) | 1.89635090 |
| 84 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.88152501 |
| 85 | Abnormality of renal resorption (HP:0011038) | 1.87411161 |
| 86 | Type I transferrin isoform profile (HP:0003642) | 1.85518120 |
| 87 | Stomatitis (HP:0010280) | 1.84525100 |
| 88 | Abnormality of T cells (HP:0002843) | 1.83733193 |
| 89 | T lymphocytopenia (HP:0005403) | 1.83250366 |
| 90 | Reduced antithrombin III activity (HP:0001976) | 1.82194669 |
| 91 | Respiratory failure (HP:0002878) | 1.79778463 |
| 92 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.77638492 |
| 93 | Recurrent bronchitis (HP:0002837) | 1.77595880 |
| 94 | Abnormality of the renal collecting system (HP:0004742) | 1.77261043 |
| 95 | Abnormality of the prostate (HP:0008775) | 1.74072911 |
| 96 | Type 2 muscle fiber atrophy (HP:0003554) | 1.73395646 |
| 97 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.72000900 |
| 98 | Exercise intolerance (HP:0003546) | 1.71000165 |
| 99 | Ketosis (HP:0001946) | 1.70404653 |
| 100 | Nephronophthisis (HP:0000090) | 1.69737121 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 3.43674633 |
| 2 | TXK | 3.20338524 |
| 3 | KDR | 3.15723997 |
| 4 | VRK2 | 3.03244081 |
| 5 | BCKDK | 2.89944222 |
| 6 | ZAK | 2.86437865 |
| 7 | GRK1 | 2.53984826 |
| 8 | KIT | 2.39311502 |
| 9 | WNK4 | 2.38891885 |
| 10 | NUAK1 | 2.20119696 |
| 11 | ADRBK2 | 2.19935966 |
| 12 | MAP4K2 | 2.15555141 |
| 13 | TLK1 | 2.00290327 |
| 14 | PINK1 | 1.84299815 |
| 15 | STK16 | 1.83645748 |
| 16 | MAP4K1 | 1.80137494 |
| 17 | TAOK3 | 1.79294990 |
| 18 | TIE1 | 1.79103341 |
| 19 | TEC | 1.73819613 |
| 20 | STK39 | 1.71955566 |
| 21 | FES | 1.70919685 |
| 22 | VRK1 | 1.70888849 |
| 23 | CDK19 | 1.64736276 |
| 24 | GRK7 | 1.53431853 |
| 25 | BUB1 | 1.45538045 |
| 26 | NME2 | 1.40532607 |
| 27 | FRK | 1.29408919 |
| 28 | PASK | 1.24078472 |
| 29 | SYK | 1.18012523 |
| 30 | PRKCQ | 1.15410351 |
| 31 | MST4 | 1.13134878 |
| 32 | INSRR | 1.10054946 |
| 33 | IKBKB | 1.08402857 |
| 34 | LIMK1 | 1.08395114 |
| 35 | TESK1 | 1.04381512 |
| 36 | WNK3 | 1.04377570 |
| 37 | NME1 | 1.03290702 |
| 38 | ITK | 1.02241140 |
| 39 | EIF2AK3 | 0.92896554 |
| 40 | JAK3 | 0.92001996 |
| 41 | GRK5 | 0.91949917 |
| 42 | IKBKE | 0.91630970 |
| 43 | MUSK | 0.87970005 |
| 44 | SCYL2 | 0.85060044 |
| 45 | STK24 | 0.84064989 |
| 46 | TNK2 | 0.83917695 |
| 47 | MAPKAPK3 | 0.82823916 |
| 48 | ADRBK1 | 0.81085680 |
| 49 | AURKA | 0.80324387 |
| 50 | CCNB1 | 0.78790148 |
| 51 | DYRK2 | 0.77595085 |
| 52 | RPS6KA5 | 0.75501985 |
| 53 | CSF1R | 0.75449855 |
| 54 | LCK | 0.73641849 |
| 55 | DAPK1 | 0.72467238 |
| 56 | MAP3K11 | 0.71331998 |
| 57 | GRK6 | 0.70635174 |
| 58 | RPS6KB2 | 0.66615004 |
| 59 | OBSCN | 0.65869308 |
| 60 | LYN | 0.65279437 |
| 61 | EIF2AK2 | 0.65150784 |
| 62 | ILK | 0.63287322 |
| 63 | CAMKK2 | 0.62918929 |
| 64 | NEK1 | 0.62039365 |
| 65 | OXSR1 | 0.61504644 |
| 66 | ACVR1B | 0.59508087 |
| 67 | PIM1 | 0.58881798 |
| 68 | TAF1 | 0.57552019 |
| 69 | BMPR1B | 0.57342956 |
| 70 | BTK | 0.57044796 |
| 71 | CHEK2 | 0.56465127 |
| 72 | TRIM28 | 0.55934662 |
| 73 | TGFBR2 | 0.55541892 |
| 74 | MAP3K12 | 0.55430651 |
| 75 | CSNK1G3 | 0.54437939 |
| 76 | PIM2 | 0.52000031 |
| 77 | MAPKAPK5 | 0.51149530 |
| 78 | PLK4 | 0.50803989 |
| 79 | PRKACA | 0.49109314 |
| 80 | MOS | 0.48691338 |
| 81 | MAPK13 | 0.47213284 |
| 82 | CSNK2A1 | 0.46924241 |
| 83 | CDC7 | 0.46913683 |
| 84 | PHKG1 | 0.44091919 |
| 85 | PHKG2 | 0.44091919 |
| 86 | PRKCA | 0.44026418 |
| 87 | MAP2K7 | 0.43936676 |
| 88 | PLK3 | 0.43661350 |
| 89 | PIK3CG | 0.43429162 |
| 90 | RPS6KA6 | 0.41512458 |
| 91 | PRKCD | 0.41478629 |
| 92 | PLK1 | 0.40899060 |
| 93 | IGF1R | 0.40885195 |
| 94 | DAPK3 | 0.40718314 |
| 95 | PRKCG | 0.38193988 |
| 96 | SRPK1 | 0.37898675 |
| 97 | PDK2 | 0.37397990 |
| 98 | DAPK2 | 0.37349962 |
| 99 | MATK | 0.37232871 |
| 100 | CSNK2A2 | 0.37200356 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.55182095 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.89251182 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.52140947 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.46227224 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.79350933 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.24688992 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.10360323 |
| 8 | Protein export_Homo sapiens_hsa03060 | 1.97408566 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 1.90296164 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 1.86273350 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 1.84156853 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 1.82550635 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.81472353 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.75447692 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.66638134 |
| 16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.59225249 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.58062129 |
| 18 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.57854215 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.56216776 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.55906053 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.53934942 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.49649753 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.49327362 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.44334011 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.43629221 |
| 26 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.43374244 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.39503781 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.37912583 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.35946508 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.34246422 |
| 31 | DNA replication_Homo sapiens_hsa03030 | 1.33658800 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.33454245 |
| 33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.29603488 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.28307267 |
| 35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24980019 |
| 36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.19124201 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.14301126 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.10460149 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 1.09386771 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08866127 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 1.07770077 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.05509489 |
| 43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.03840206 |
| 44 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.02563281 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 1.01345957 |
| 46 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.94201786 |
| 47 | Retinol metabolism_Homo sapiens_hsa00830 | 0.90558781 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89906157 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.88598317 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.88583524 |
| 51 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85394318 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.83931764 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.83867006 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.83297386 |
| 55 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.82144930 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.82108651 |
| 57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.80418148 |
| 58 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.80262435 |
| 59 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79571141 |
| 60 | Olfactory transduction_Homo sapiens_hsa04740 | 0.78703188 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.78072107 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78021849 |
| 63 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.75899793 |
| 64 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74661426 |
| 65 | RNA transport_Homo sapiens_hsa03013 | 0.74113802 |
| 66 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72971091 |
| 67 | Sulfur relay system_Homo sapiens_hsa04122 | 0.70979573 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70222215 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69233806 |
| 70 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.64998293 |
| 71 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.64088943 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.63949693 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.63186451 |
| 74 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61677271 |
| 75 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60760713 |
| 76 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.59594702 |
| 77 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.57428364 |
| 78 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.57298359 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.56925151 |
| 80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56023719 |
| 81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54193466 |
| 82 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52260804 |
| 83 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50777681 |
| 84 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.48721856 |
| 85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48287350 |
| 86 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.46205283 |
| 87 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46027749 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.45668795 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44494898 |
| 90 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.43604454 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.36919949 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36796297 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.34684915 |
| 94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33805968 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.33710502 |
| 96 | Measles_Homo sapiens_hsa05162 | 0.33594779 |
| 97 | Viral myocarditis_Homo sapiens_hsa05416 | 0.32776367 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.32695162 |
| 99 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.31888414 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.31875903 |

