

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 7.43660812 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 7.42634156 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 7.32897566 |
| 4 | translational termination (GO:0006415) | 7.10664620 |
| 5 | maturation of SSU-rRNA (GO:0030490) | 6.96042230 |
| 6 | translational elongation (GO:0006414) | 6.26900822 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.16755488 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 6.05883049 |
| 9 | protein targeting to ER (GO:0045047) | 6.02243984 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.77595347 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 5.63307954 |
| 12 | viral life cycle (GO:0019058) | 5.35383982 |
| 13 | cellular protein complex disassembly (GO:0043624) | 5.32930239 |
| 14 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.30758867 |
| 15 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.30758867 |
| 16 | chaperone-mediated protein transport (GO:0072321) | 5.24131291 |
| 17 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.18804796 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.11280800 |
| 19 | translational initiation (GO:0006413) | 4.96297588 |
| 20 | ATP synthesis coupled proton transport (GO:0015986) | 4.92449569 |
| 21 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.92449569 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 4.91779244 |
| 23 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.76015282 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.54531801 |
| 25 | protein complex disassembly (GO:0043241) | 4.49322534 |
| 26 | translation (GO:0006412) | 4.42073352 |
| 27 | cellular component biogenesis (GO:0044085) | 4.37398566 |
| 28 | protein complex biogenesis (GO:0070271) | 4.37387888 |
| 29 | macromolecular complex disassembly (GO:0032984) | 4.35529566 |
| 30 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.18515642 |
| 31 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.10458123 |
| 32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.10458123 |
| 33 | NADH dehydrogenase complex assembly (GO:0010257) | 4.10458123 |
| 34 | respiratory electron transport chain (GO:0022904) | 3.97508976 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.96197302 |
| 36 | protein targeting to membrane (GO:0006612) | 3.94645551 |
| 37 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.92057276 |
| 38 | electron transport chain (GO:0022900) | 3.91764787 |
| 39 | ribosome biogenesis (GO:0042254) | 3.85065864 |
| 40 | GTP biosynthetic process (GO:0006183) | 3.82303173 |
| 41 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.79700648 |
| 42 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.74191795 |
| 43 | regulation of mitochondrial translation (GO:0070129) | 3.67960666 |
| 44 | behavioral response to nicotine (GO:0035095) | 3.66043405 |
| 45 | cardiovascular system development (GO:0072358) | 3.63650577 |
| 46 | mRNA catabolic process (GO:0006402) | 3.55069278 |
| 47 | rRNA processing (GO:0006364) | 3.49349795 |
| 48 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.45223346 |
| 49 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.41926430 |
| 50 | rRNA metabolic process (GO:0016072) | 3.37420399 |
| 51 | pseudouridine synthesis (GO:0001522) | 3.33761805 |
| 52 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.32979835 |
| 53 | kinetochore assembly (GO:0051382) | 3.31725983 |
| 54 | UTP biosynthetic process (GO:0006228) | 3.30618252 |
| 55 | protein-cofactor linkage (GO:0018065) | 3.29429463 |
| 56 | DNA damage response, detection of DNA damage (GO:0042769) | 3.29177358 |
| 57 | termination of RNA polymerase III transcription (GO:0006386) | 3.25659174 |
| 58 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.25659174 |
| 59 | protein targeting to mitochondrion (GO:0006626) | 3.24469477 |
| 60 | establishment of mitochondrion localization (GO:0051654) | 3.21809113 |
| 61 | rRNA modification (GO:0000154) | 3.19216303 |
| 62 | RNA catabolic process (GO:0006401) | 3.18817201 |
| 63 | proteasome assembly (GO:0043248) | 3.17800583 |
| 64 | base-excision repair, AP site formation (GO:0006285) | 3.11740532 |
| 65 | mitochondrion transport along microtubule (GO:0047497) | 3.07944246 |
| 66 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.07944246 |
| 67 | ncRNA 3-end processing (GO:0043628) | 3.07831884 |
| 68 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.06371956 |
| 69 | platelet dense granule organization (GO:0060155) | 3.05743321 |
| 70 | UTP metabolic process (GO:0046051) | 3.05452871 |
| 71 | establishment of protein localization to mitochondrion (GO:0072655) | 3.02575512 |
| 72 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.00558425 |
| 73 | L-serine metabolic process (GO:0006563) | 2.99312068 |
| 74 | cell proliferation in forebrain (GO:0021846) | 2.97998127 |
| 75 | signal peptide processing (GO:0006465) | 2.96862809 |
| 76 | protein localization to mitochondrion (GO:0070585) | 2.96246346 |
| 77 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.96227196 |
| 78 | tRNA processing (GO:0008033) | 2.95999087 |
| 79 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.95961945 |
| 80 | amino acid salvage (GO:0043102) | 2.95875960 |
| 81 | L-methionine salvage (GO:0071267) | 2.95875960 |
| 82 | L-methionine biosynthetic process (GO:0071265) | 2.95875960 |
| 83 | protein targeting (GO:0006605) | 2.85550193 |
| 84 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.81739805 |
| 85 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.79679262 |
| 86 | DNA deamination (GO:0045006) | 2.79219605 |
| 87 | branched-chain amino acid catabolic process (GO:0009083) | 2.78541899 |
| 88 | single strand break repair (GO:0000012) | 2.78151324 |
| 89 | ncRNA processing (GO:0034470) | 2.76315675 |
| 90 | ATP biosynthetic process (GO:0006754) | 2.74744294 |
| 91 | sulfur amino acid catabolic process (GO:0000098) | 2.66533820 |
| 92 | kinetochore organization (GO:0051383) | 2.66334617 |
| 93 | establishment of protein localization to organelle (GO:0072594) | 2.66265517 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.65516019 |
| 95 | hydrogen ion transmembrane transport (GO:1902600) | 2.64539665 |
| 96 | response to gravity (GO:0009629) | 2.62596354 |
| 97 | establishment of protein localization to membrane (GO:0090150) | 2.60373857 |
| 98 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.59928192 |
| 99 | CTP biosynthetic process (GO:0006241) | 2.59135080 |
| 100 | CTP metabolic process (GO:0046036) | 2.59135080 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.91970410 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.20730396 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.68102255 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.66777972 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.63485798 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.25949380 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.23774155 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 3.13280150 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.99400814 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.95192348 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.79475605 |
| 12 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.57699733 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.55763157 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.19353707 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.11611058 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.10965580 |
| 17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.06482023 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04368976 |
| 19 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.02325804 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.02136819 |
| 21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.96757538 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.95658238 |
| 23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.95328979 |
| 24 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.88873710 |
| 25 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.76494117 |
| 26 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.76278952 |
| 27 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.75655538 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.75559528 |
| 29 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.74624547 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.72127867 |
| 31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.64766687 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.59259664 |
| 33 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.55308202 |
| 34 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.53232214 |
| 35 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.52096466 |
| 36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.51176946 |
| 37 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.39925056 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.39137659 |
| 39 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.39101072 |
| 40 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.38159066 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.33739012 |
| 42 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.33524571 |
| 43 | EWS_26573619_Chip-Seq_HEK293_Human | 1.32974968 |
| 44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.30624722 |
| 45 | FUS_26573619_Chip-Seq_HEK293_Human | 1.29916033 |
| 46 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.29555990 |
| 47 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.27818752 |
| 48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.24564723 |
| 49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.24554660 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23364962 |
| 51 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.22616282 |
| 52 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.21106815 |
| 53 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.19754342 |
| 54 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.18680018 |
| 55 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.15898470 |
| 56 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.15308707 |
| 57 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.12558306 |
| 58 | ERA_21632823_ChIP-Seq_H3396_Human | 1.11938613 |
| 59 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.11864905 |
| 60 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.08308623 |
| 61 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.07947956 |
| 62 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.07804774 |
| 63 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07115055 |
| 64 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.06883061 |
| 65 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.01203299 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.01002016 |
| 67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.00844257 |
| 68 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.98599455 |
| 69 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.96657276 |
| 70 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.95952994 |
| 71 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.95253590 |
| 72 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.92336336 |
| 73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.91575981 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 0.91365879 |
| 75 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90973515 |
| 76 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.90621826 |
| 77 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.90084574 |
| 78 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.89226044 |
| 79 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.89030594 |
| 80 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.88594821 |
| 81 | AR_20517297_ChIP-Seq_VCAP_Human | 0.88186696 |
| 82 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.87838515 |
| 83 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.86801611 |
| 84 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.85782810 |
| 85 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.85491015 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.85491015 |
| 87 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.85394745 |
| 88 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.83557033 |
| 89 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.83305269 |
| 90 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.83090483 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.83034722 |
| 92 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.81349305 |
| 93 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.80877437 |
| 94 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.80379243 |
| 95 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.80262083 |
| 96 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.79964602 |
| 97 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.79477686 |
| 98 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.79459043 |
| 99 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.79385521 |
| 100 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.78389713 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.34045014 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.37919939 |
| 3 | MP0000372_irregular_coat_pigmentation | 3.74879163 |
| 4 | MP0003136_yellow_coat_color | 3.25416137 |
| 5 | MP0003646_muscle_fatigue | 3.01104214 |
| 6 | MP0002736_abnormal_nociception_after | 2.85843567 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.54284238 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.53011816 |
| 9 | MP0002163_abnormal_gland_morphology | 2.43761140 |
| 10 | MP0002095_abnormal_skin_pigmentation | 2.42791226 |
| 11 | MP0002938_white_spotting | 2.07472137 |
| 12 | MP0008789_abnormal_olfactory_epithelium | 1.99552349 |
| 13 | MP0001293_anophthalmia | 1.95978924 |
| 14 | MP0003880_abnormal_central_pattern | 1.91840343 |
| 15 | MP0002102_abnormal_ear_morphology | 1.85938473 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.80652287 |
| 17 | MP0005670_abnormal_white_adipose | 1.74504134 |
| 18 | MP0005646_abnormal_pituitary_gland | 1.73718510 |
| 19 | MP0004885_abnormal_endolymph | 1.72704726 |
| 20 | MP0000631_abnormal_neuroendocrine_gland | 1.71158689 |
| 21 | MP0002638_abnormal_pupillary_reflex | 1.69724254 |
| 22 | MP0000049_abnormal_middle_ear | 1.68693150 |
| 23 | MP0004142_abnormal_muscle_tone | 1.64939483 |
| 24 | MP0008877_abnormal_DNA_methylation | 1.64591186 |
| 25 | MP0006072_abnormal_retinal_apoptosis | 1.59971903 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.55714842 |
| 27 | MP0003186_abnormal_redox_activity | 1.50498041 |
| 28 | MP0008872_abnormal_physiological_respon | 1.48065898 |
| 29 | MP0004133_heterotaxia | 1.46134202 |
| 30 | MP0003123_paternal_imprinting | 1.44571767 |
| 31 | MP0005499_abnormal_olfactory_system | 1.41796146 |
| 32 | MP0005394_taste/olfaction_phenotype | 1.41796146 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.40002800 |
| 34 | MP0003937_abnormal_limbs/digits/tail_de | 1.37081936 |
| 35 | MP0001502_abnormal_circadian_rhythm | 1.34247154 |
| 36 | MP0008058_abnormal_DNA_repair | 1.25871490 |
| 37 | MP0002160_abnormal_reproductive_system | 1.21381340 |
| 38 | MP0009250_abnormal_appendicular_skeleto | 1.21233876 |
| 39 | MP0006276_abnormal_autonomic_nervous | 1.21174544 |
| 40 | MP0002234_abnormal_pharynx_morphology | 1.20002415 |
| 41 | MP0000647_abnormal_sebaceous_gland | 1.19341468 |
| 42 | MP0004147_increased_porphyrin_level | 1.19032092 |
| 43 | MP0002277_abnormal_respiratory_mucosa | 1.14818119 |
| 44 | MP0009745_abnormal_behavioral_response | 1.14383863 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.12806466 |
| 46 | MP0005253_abnormal_eye_physiology | 1.08747718 |
| 47 | MP0003122_maternal_imprinting | 1.08449374 |
| 48 | MP0001986_abnormal_taste_sensitivity | 1.08339308 |
| 49 | MP0008995_early_reproductive_senescence | 1.05511775 |
| 50 | MP0001529_abnormal_vocalization | 1.05274932 |
| 51 | MP0001486_abnormal_startle_reflex | 1.05130408 |
| 52 | MP0002837_dystrophic_cardiac_calcinosis | 1.04461524 |
| 53 | MP0005075_abnormal_melanosome_morpholog | 1.03911020 |
| 54 | MP0005195_abnormal_posterior_eye | 1.03872899 |
| 55 | MP0005389_reproductive_system_phenotype | 1.03835589 |
| 56 | MP0009053_abnormal_anal_canal | 1.03331231 |
| 57 | MP0005645_abnormal_hypothalamus_physiol | 0.99116205 |
| 58 | MP0005379_endocrine/exocrine_gland_phen | 0.96890478 |
| 59 | MP0002272_abnormal_nervous_system | 0.96858707 |
| 60 | MP0000026_abnormal_inner_ear | 0.96813913 |
| 61 | MP0009046_muscle_twitch | 0.96387398 |
| 62 | MP0000566_synostosis | 0.93199651 |
| 63 | MP0001764_abnormal_homeostasis | 0.93095315 |
| 64 | MP0002557_abnormal_social/conspecific_i | 0.92340250 |
| 65 | MP0002876_abnormal_thyroid_physiology | 0.92222608 |
| 66 | MP0001286_abnormal_eye_development | 0.89561845 |
| 67 | MP0002249_abnormal_larynx_morphology | 0.89012708 |
| 68 | MP0001963_abnormal_hearing_physiology | 0.88902103 |
| 69 | MP0001905_abnormal_dopamine_level | 0.88851582 |
| 70 | MP0002210_abnormal_sex_determination | 0.86270844 |
| 71 | MP0003787_abnormal_imprinting | 0.85772929 |
| 72 | MP0003183_abnormal_peptide_metabolism | 0.85701155 |
| 73 | MP0001270_distended_abdomen | 0.85222674 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.85087054 |
| 75 | MP0003755_abnormal_palate_morphology | 0.84926546 |
| 76 | MP0010030_abnormal_orbit_morphology | 0.83590909 |
| 77 | MP0003942_abnormal_urinary_system | 0.83351959 |
| 78 | MP0003878_abnormal_ear_physiology | 0.82763275 |
| 79 | MP0005377_hearing/vestibular/ear_phenot | 0.82763275 |
| 80 | MP0002752_abnormal_somatic_nervous | 0.80835851 |
| 81 | MP0002233_abnormal_nose_morphology | 0.80657687 |
| 82 | MP0005391_vision/eye_phenotype | 0.80237132 |
| 83 | MP0003718_maternal_effect | 0.80155763 |
| 84 | MP0000778_abnormal_nervous_system | 0.79279816 |
| 85 | MP0001919_abnormal_reproductive_system | 0.78098557 |
| 86 | MP0003938_abnormal_ear_development | 0.77792051 |
| 87 | MP0003011_delayed_dark_adaptation | 0.77507904 |
| 88 | MP0002733_abnormal_thermal_nociception | 0.76874870 |
| 89 | MP0003936_abnormal_reproductive_system | 0.74332553 |
| 90 | MP0003121_genomic_imprinting | 0.73851516 |
| 91 | MP0000427_abnormal_hair_cycle | 0.73821270 |
| 92 | MP0000534_abnormal_ureter_morphology | 0.73090006 |
| 93 | MP0002254_reproductive_system_inflammat | 0.72761984 |
| 94 | MP0005360_urolithiasis | 0.70929953 |
| 95 | MP0002109_abnormal_limb_morphology | 0.70290666 |
| 96 | MP0001324_abnormal_eye_pigmentation | 0.69094304 |
| 97 | MP0002697_abnormal_eye_size | 0.68496651 |
| 98 | MP0002132_abnormal_respiratory_system | 0.68265756 |
| 99 | MP0005636_abnormal_mineral_homeostasis | 0.67558090 |
| 100 | MP0002067_abnormal_sensory_capabilities | 0.67195810 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.94160931 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.89432401 |
| 3 | Pendular nystagmus (HP:0012043) | 4.43987987 |
| 4 | Acute encephalopathy (HP:0006846) | 4.40676760 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.29469989 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.28528902 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.98932375 |
| 8 | Congenital stationary night blindness (HP:0007642) | 3.79096979 |
| 9 | Hyperglycinemia (HP:0002154) | 3.74072724 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.63277211 |
| 11 | Decreased central vision (HP:0007663) | 3.55074863 |
| 12 | Macrocytic anemia (HP:0001972) | 3.46188532 |
| 13 | Increased CSF lactate (HP:0002490) | 3.43212785 |
| 14 | Abnormality of alanine metabolism (HP:0010916) | 3.35052717 |
| 15 | Hyperalaninemia (HP:0003348) | 3.35052717 |
| 16 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.35052717 |
| 17 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.11331998 |
| 18 | Increased corneal curvature (HP:0100692) | 3.06176615 |
| 19 | Keratoconus (HP:0000563) | 3.06176615 |
| 20 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.04385052 |
| 21 | Cerebral edema (HP:0002181) | 2.97382666 |
| 22 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.95226400 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.93351617 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.93351617 |
| 25 | Colon cancer (HP:0003003) | 2.90079392 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.85936643 |
| 27 | Optic disc pallor (HP:0000543) | 2.81642411 |
| 28 | Pancreatic cysts (HP:0001737) | 2.80247152 |
| 29 | Stenosis of the external auditory canal (HP:0000402) | 2.75240577 |
| 30 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.73135069 |
| 31 | True hermaphroditism (HP:0010459) | 2.69543834 |
| 32 | Hepatocellular necrosis (HP:0001404) | 2.69216603 |
| 33 | Pallor (HP:0000980) | 2.68892470 |
| 34 | Absent thumb (HP:0009777) | 2.64560482 |
| 35 | Pancreatic fibrosis (HP:0100732) | 2.61515845 |
| 36 | Anencephaly (HP:0002323) | 2.58705424 |
| 37 | Delayed CNS myelination (HP:0002188) | 2.57815003 |
| 38 | Constricted visual fields (HP:0001133) | 2.55144430 |
| 39 | Nephronophthisis (HP:0000090) | 2.49838865 |
| 40 | Hepatic necrosis (HP:0002605) | 2.44935921 |
| 41 | Increased serum lactate (HP:0002151) | 2.44109425 |
| 42 | Septo-optic dysplasia (HP:0100842) | 2.42654790 |
| 43 | Abnormality of serum amino acid levels (HP:0003112) | 2.38694557 |
| 44 | Abnormal drinking behavior (HP:0030082) | 2.31360274 |
| 45 | Polydipsia (HP:0001959) | 2.31360274 |
| 46 | Lactic acidosis (HP:0003128) | 2.29617129 |
| 47 | Abnormal number of erythroid precursors (HP:0012131) | 2.29456982 |
| 48 | Occipital encephalocele (HP:0002085) | 2.27021601 |
| 49 | Maternal diabetes (HP:0009800) | 2.21927441 |
| 50 | Abnormality of the labia minora (HP:0012880) | 2.21362540 |
| 51 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.16872731 |
| 52 | Lethargy (HP:0001254) | 2.15869787 |
| 53 | Hypoplasia of the radius (HP:0002984) | 2.14669926 |
| 54 | Type 2 muscle fiber atrophy (HP:0003554) | 2.14058432 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.12262458 |
| 56 | Type II lissencephaly (HP:0007260) | 2.12164090 |
| 57 | Cerebral hypomyelination (HP:0006808) | 2.10162845 |
| 58 | Concave nail (HP:0001598) | 2.06559043 |
| 59 | Exercise intolerance (HP:0003546) | 2.04068955 |
| 60 | Attenuation of retinal blood vessels (HP:0007843) | 2.03792827 |
| 61 | Respiratory failure (HP:0002878) | 2.03596367 |
| 62 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.00669414 |
| 63 | Abolished electroretinogram (ERG) (HP:0000550) | 1.99986480 |
| 64 | Abnormality of the renal medulla (HP:0100957) | 1.99933446 |
| 65 | Increased hepatocellular lipid droplets (HP:0006565) | 1.99337270 |
| 66 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.97888705 |
| 67 | Abnormality of glycine metabolism (HP:0010895) | 1.97888705 |
| 68 | Optic nerve hypoplasia (HP:0000609) | 1.96851449 |
| 69 | Asplenia (HP:0001746) | 1.95698504 |
| 70 | Methylmalonic acidemia (HP:0002912) | 1.95475410 |
| 71 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.95427657 |
| 72 | Palpebral edema (HP:0100540) | 1.93962852 |
| 73 | Oligodactyly (hands) (HP:0001180) | 1.90563512 |
| 74 | Absent phalangeal crease (HP:0006109) | 1.89416584 |
| 75 | Leukodystrophy (HP:0002415) | 1.87676313 |
| 76 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.86931667 |
| 77 | Supernumerary spleens (HP:0009799) | 1.84705885 |
| 78 | Testicular atrophy (HP:0000029) | 1.84614359 |
| 79 | Methylmalonic aciduria (HP:0012120) | 1.84347018 |
| 80 | Oligomenorrhea (HP:0000876) | 1.83969103 |
| 81 | Forearm undergrowth (HP:0009821) | 1.82256862 |
| 82 | Short tibia (HP:0005736) | 1.79540164 |
| 83 | Muscle fiber atrophy (HP:0100295) | 1.79238287 |
| 84 | Cleft eyelid (HP:0000625) | 1.78781657 |
| 85 | Optic nerve coloboma (HP:0000588) | 1.78744421 |
| 86 | Chorioretinal atrophy (HP:0000533) | 1.78245422 |
| 87 | Congenital sensorineural hearing impairment (HP:0008527) | 1.77508188 |
| 88 | Postaxial foot polydactyly (HP:0001830) | 1.75466471 |
| 89 | Ectopic kidney (HP:0000086) | 1.75075829 |
| 90 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.74859629 |
| 91 | Lipid accumulation in hepatocytes (HP:0006561) | 1.71620791 |
| 92 | Hypoplasia of the ulna (HP:0003022) | 1.71536468 |
| 93 | Fibular aplasia (HP:0002990) | 1.71366202 |
| 94 | Partial duplication of thumb phalanx (HP:0009944) | 1.71154783 |
| 95 | Triphalangeal thumb (HP:0001199) | 1.71112427 |
| 96 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.71013705 |
| 97 | Polyuria (HP:0000103) | 1.70760383 |
| 98 | Blindness (HP:0000618) | 1.70099098 |
| 99 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.70071287 |
| 100 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.67659420 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.98233162 |
| 2 | NME2 | 3.86980244 |
| 3 | WNK4 | 3.08053443 |
| 4 | TESK2 | 2.81596621 |
| 5 | GRK1 | 2.73987608 |
| 6 | STK16 | 2.68039263 |
| 7 | WNK3 | 2.50598312 |
| 8 | NUAK1 | 2.42807852 |
| 9 | DYRK2 | 2.21701589 |
| 10 | EPHA4 | 2.12451794 |
| 11 | BCKDK | 2.07726511 |
| 12 | FRK | 2.05848881 |
| 13 | VRK2 | 1.95995003 |
| 14 | TLK1 | 1.88958551 |
| 15 | PINK1 | 1.84315471 |
| 16 | ZAK | 1.73251399 |
| 17 | PDK2 | 1.65079398 |
| 18 | PHKG1 | 1.62927769 |
| 19 | PHKG2 | 1.62927769 |
| 20 | CDK19 | 1.59440919 |
| 21 | TRIM28 | 1.54336494 |
| 22 | CDC7 | 1.50658419 |
| 23 | STK39 | 1.47890545 |
| 24 | PIK3CA | 1.44010064 |
| 25 | ADRBK2 | 1.30783200 |
| 26 | SRPK1 | 1.24866169 |
| 27 | ABL2 | 1.22177511 |
| 28 | MAPK13 | 1.19770674 |
| 29 | OBSCN | 1.19538732 |
| 30 | MAP2K7 | 1.16342643 |
| 31 | MAP3K11 | 1.15078912 |
| 32 | INSRR | 1.11729344 |
| 33 | LRRK2 | 1.11135663 |
| 34 | CAMK1 | 1.10213284 |
| 35 | TIE1 | 1.09924961 |
| 36 | MAP3K4 | 1.07250859 |
| 37 | PRKCI | 1.02390020 |
| 38 | AURKA | 1.01266197 |
| 39 | PRKCG | 0.97980679 |
| 40 | NEK2 | 0.97858730 |
| 41 | MARK3 | 0.93147295 |
| 42 | CASK | 0.91403417 |
| 43 | BMPR1B | 0.88934158 |
| 44 | WNK1 | 0.88752502 |
| 45 | OXSR1 | 0.87860145 |
| 46 | PNCK | 0.86083566 |
| 47 | RPS6KA5 | 0.85469523 |
| 48 | CSNK1G2 | 0.84113003 |
| 49 | KDR | 0.84077848 |
| 50 | EPHB2 | 0.83554213 |
| 51 | PAK3 | 0.82883320 |
| 52 | BUB1 | 0.80493232 |
| 53 | NTRK2 | 0.78279155 |
| 54 | CSNK1G3 | 0.72942460 |
| 55 | PRKCQ | 0.72240776 |
| 56 | SIK2 | 0.71562685 |
| 57 | CSNK2A2 | 0.69440645 |
| 58 | PRKACA | 0.68613416 |
| 59 | CAMKK2 | 0.68471431 |
| 60 | NEK1 | 0.67401537 |
| 61 | AURKB | 0.66042108 |
| 62 | RPS6KB2 | 0.65324403 |
| 63 | VRK1 | 0.65227965 |
| 64 | MKNK2 | 0.65058078 |
| 65 | ACVR1B | 0.64722744 |
| 66 | PLK1 | 0.64186307 |
| 67 | CAMK1G | 0.63634767 |
| 68 | TAF1 | 0.62762920 |
| 69 | CAMK2D | 0.62599519 |
| 70 | CSNK2A1 | 0.60981813 |
| 71 | PBK | 0.60595421 |
| 72 | TEC | 0.60408363 |
| 73 | PLK4 | 0.58554688 |
| 74 | CSNK1A1 | 0.57912143 |
| 75 | RPS6KB1 | 0.57736514 |
| 76 | PRKCE | 0.57353117 |
| 77 | DAPK2 | 0.55668200 |
| 78 | ADRBK1 | 0.55177605 |
| 79 | CSNK1G1 | 0.54285795 |
| 80 | JAK3 | 0.52391314 |
| 81 | CHEK2 | 0.51401025 |
| 82 | LIMK1 | 0.50935777 |
| 83 | MKNK1 | 0.49062199 |
| 84 | PLK2 | 0.48182185 |
| 85 | CAMK2G | 0.46285150 |
| 86 | CSNK1E | 0.46032076 |
| 87 | MARK1 | 0.45532364 |
| 88 | MAP4K1 | 0.44204703 |
| 89 | CSNK1A1L | 0.43946379 |
| 90 | PRKAA2 | 0.43800618 |
| 91 | NME1 | 0.42255815 |
| 92 | CCNB1 | 0.42039667 |
| 93 | PLK3 | 0.40166911 |
| 94 | MUSK | 0.37480533 |
| 95 | PRKCA | 0.36513642 |
| 96 | RPS6KA6 | 0.35611258 |
| 97 | PRKACB | 0.35559526 |
| 98 | CAMK1D | 0.35192394 |
| 99 | RPS6KA4 | 0.34984527 |
| 100 | PASK | 0.34377005 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.50435682 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.11553607 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.32252363 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 3.15192061 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.61464644 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.37557764 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.20256863 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.18412060 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.11500678 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.09125955 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.06802703 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.99615089 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.90408096 |
| 14 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.83683973 |
| 15 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.78665260 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.74473005 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.63903803 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.63253600 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.59201122 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.58968333 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.52764317 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.45613553 |
| 23 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.44557004 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.43899456 |
| 25 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.36554140 |
| 26 | Allograft rejection_Homo sapiens_hsa05330 | 1.28969458 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.26579583 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.22815596 |
| 29 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.21509006 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.17496966 |
| 31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.16168183 |
| 32 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.15175645 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12983680 |
| 34 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.09169295 |
| 35 | Base excision repair_Homo sapiens_hsa03410 | 1.05091945 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.03917243 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03420283 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.03129935 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.00332084 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.99470148 |
| 41 | RNA transport_Homo sapiens_hsa03013 | 0.99419305 |
| 42 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.98302478 |
| 43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.90768247 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.90658317 |
| 45 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88765618 |
| 46 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.87713563 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85655291 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.82751800 |
| 49 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.82585079 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81226331 |
| 51 | Retinol metabolism_Homo sapiens_hsa00830 | 0.75480060 |
| 52 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.75348084 |
| 53 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74443483 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74383356 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.72072567 |
| 56 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.67135741 |
| 57 | Nicotine addiction_Homo sapiens_hsa05033 | 0.65854378 |
| 58 | Morphine addiction_Homo sapiens_hsa05032 | 0.65690268 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.64666199 |
| 60 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.64620345 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.64108976 |
| 62 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63624497 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62095461 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61511846 |
| 65 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59710692 |
| 66 | Peroxisome_Homo sapiens_hsa04146 | 0.59117449 |
| 67 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.58390149 |
| 68 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.56124139 |
| 69 | DNA replication_Homo sapiens_hsa03030 | 0.55784372 |
| 70 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.55526444 |
| 71 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55218350 |
| 72 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.54600483 |
| 73 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52725789 |
| 74 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.51213911 |
| 75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.50560926 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48709176 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48220155 |
| 78 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.47193350 |
| 79 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46868488 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45849245 |
| 81 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.44766711 |
| 82 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.41761560 |
| 83 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.41099391 |
| 84 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.37558496 |
| 85 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.37244930 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.36794015 |
| 87 | GABAergic synapse_Homo sapiens_hsa04727 | 0.35643075 |
| 88 | Insulin secretion_Homo sapiens_hsa04911 | 0.35618119 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35287075 |
| 90 | Circadian entrainment_Homo sapiens_hsa04713 | 0.33082472 |
| 91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32118477 |
| 92 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.31478415 |
| 93 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.31054607 |
| 94 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.28095657 |
| 95 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.27977407 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27976017 |
| 97 | Mismatch repair_Homo sapiens_hsa03430 | 0.25560312 |
| 98 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25051181 |
| 99 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24228187 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.22595301 |

