RPP30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.20877820
2CENP-A containing nucleosome assembly (GO:0034080)4.58804933
3negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.41038178
4chromatin remodeling at centromere (GO:0031055)4.37496781
5ribosomal small subunit biogenesis (GO:0042274)4.24654469
6maturation of SSU-rRNA (GO:0030490)4.23649311
7positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.23303902
8anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:04.19862633
9regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.18646126
10DNA strand elongation involved in DNA replication (GO:0006271)4.16725132
11telomere maintenance via semi-conservative replication (GO:0032201)4.08938789
12protein complex biogenesis (GO:0070271)4.06799372
13mitotic metaphase plate congression (GO:0007080)4.06649408
14transcription elongation from RNA polymerase III promoter (GO:0006385)4.06089605
15termination of RNA polymerase III transcription (GO:0006386)4.06089605
16ribosomal large subunit biogenesis (GO:0042273)4.05170534
17mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.04985207
18negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.03979375
19negative regulation of ligase activity (GO:0051352)4.03979375
207-methylguanosine mRNA capping (GO:0006370)3.98016431
21mitochondrial respiratory chain complex assembly (GO:0033108)3.97594406
22DNA strand elongation (GO:0022616)3.96236872
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.95360304
24mitochondrial respiratory chain complex I assembly (GO:0032981)3.95360304
25NADH dehydrogenase complex assembly (GO:0010257)3.95360304
267-methylguanosine RNA capping (GO:0009452)3.92699346
27RNA capping (GO:0036260)3.92699346
28DNA replication checkpoint (GO:0000076)3.92637103
29DNA deamination (GO:0045006)3.89979626
30DNA double-strand break processing (GO:0000729)3.86953910
31respiratory electron transport chain (GO:0022904)3.84247529
32DNA replication-independent nucleosome organization (GO:0034724)3.83964759
33DNA replication-independent nucleosome assembly (GO:0006336)3.83964759
34cullin deneddylation (GO:0010388)3.83566701
35ribonucleoprotein complex biogenesis (GO:0022613)3.82671732
36telomere maintenance via recombination (GO:0000722)3.81530318
37viral transcription (GO:0019083)3.81265184
38DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.79616130
39purine nucleobase biosynthetic process (GO:0009113)3.79554674
40ribosomal small subunit assembly (GO:0000028)3.79428002
41translational termination (GO:0006415)3.78636795
42regulation of cellular amino acid metabolic process (GO:0006521)3.78218183
43kinetochore organization (GO:0051383)3.78079194
44electron transport chain (GO:0022900)3.77590651
45histone exchange (GO:0043486)3.76583925
46nucleobase biosynthetic process (GO:0046112)3.74749473
47formation of translation preinitiation complex (GO:0001731)3.74078520
48mitotic recombination (GO:0006312)3.73854272
49signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.73333784
50intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.73333784
51DNA replication initiation (GO:0006270)3.72825738
52signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.72401483
53signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.72401483
54signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.72401483
55transcription elongation from RNA polymerase I promoter (GO:0006362)3.72396425
56rRNA modification (GO:0000154)3.72331926
57transcription-coupled nucleotide-excision repair (GO:0006283)3.71930585
58protein deneddylation (GO:0000338)3.70058855
59respiratory chain complex IV assembly (GO:0008535)3.67664043
60positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.67660645
61protein neddylation (GO:0045116)3.66194345
62ribosome assembly (GO:0042255)3.65707762
63mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.65707472
64signal transduction involved in DNA integrity checkpoint (GO:0072401)3.64879076
65signal transduction involved in DNA damage checkpoint (GO:0072422)3.64879076
66termination of RNA polymerase I transcription (GO:0006363)3.63769884
67signal transduction involved in cell cycle checkpoint (GO:0072395)3.62184818
68ribosome biogenesis (GO:0042254)3.61799759
69spliceosomal snRNP assembly (GO:0000387)3.60323262
70regulation of mitochondrial translation (GO:0070129)3.57636105
71kinetochore assembly (GO:0051382)3.57442888
72rRNA processing (GO:0006364)3.55020528
73positive regulation of ligase activity (GO:0051351)3.54123621
74establishment of protein localization to mitochondrial membrane (GO:0090151)3.52978024
75establishment of integrated proviral latency (GO:0075713)3.52181842
76regulation of mitotic spindle checkpoint (GO:1903504)3.51301081
77regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.51301081
78transcription from RNA polymerase I promoter (GO:0006360)3.50419683
79metaphase plate congression (GO:0051310)3.47565088
80L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.45637519
81SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.45167017
82translational initiation (GO:0006413)3.44595515
83cotranslational protein targeting to membrane (GO:0006613)3.44512753
84negative regulation of DNA-dependent DNA replication (GO:2000104)3.44153461
85cytochrome complex assembly (GO:0017004)3.42998649
86rRNA metabolic process (GO:0016072)3.41509882
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.41472248
88replication fork processing (GO:0031297)3.41461164
89DNA catabolic process, exonucleolytic (GO:0000738)3.39856140
90ATP synthesis coupled proton transport (GO:0015986)3.39609976
91energy coupled proton transport, down electrochemical gradient (GO:0015985)3.39609976
92protein targeting to ER (GO:0045047)3.37828957
93cell cycle G1/S phase transition (GO:0044843)3.35633439
94G1/S transition of mitotic cell cycle (GO:0000082)3.35633439
95attachment of spindle microtubules to kinetochore (GO:0008608)3.35323254
96translational elongation (GO:0006414)3.35012520
97translation (GO:0006412)3.34527611
98cellular component biogenesis (GO:0044085)3.31969896
99DNA damage response, detection of DNA damage (GO:0042769)3.31424194
100regulation of ubiquitin-protein transferase activity (GO:0051438)3.29835586
101nucleotide-excision repair, DNA gap filling (GO:0006297)3.28282143
102spliceosomal complex assembly (GO:0000245)3.26190655
103telomere maintenance via telomere lengthening (GO:0010833)3.26166349
104exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.25234490
105nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.24787081
106pseudouridine synthesis (GO:0001522)3.24560380
107water-soluble vitamin biosynthetic process (GO:0042364)3.24116195
108protein localization to endoplasmic reticulum (GO:0070972)3.23769123
109transcription initiation from RNA polymerase I promoter (GO:0006361)3.21925529
110postreplication repair (GO:0006301)3.21670794
111establishment of protein localization to endoplasmic reticulum (GO:0072599)3.21509471
112regulation of ligase activity (GO:0051340)3.20126088
113organelle disassembly (GO:1903008)3.20029580
114deoxyribonucleotide biosynthetic process (GO:0009263)3.19607390
115regulation of nuclear cell cycle DNA replication (GO:0033262)3.19240484
116protein K6-linked ubiquitination (GO:0085020)3.18531701
117protein localization to kinetochore (GO:0034501)3.18303617
118transcription elongation from RNA polymerase II promoter (GO:0006368)3.16902887
119tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.15670391
120RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.15670391
121protein targeting to mitochondrion (GO:0006626)3.15523936
122antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.15378345
123deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.13381051
124cellular protein complex disassembly (GO:0043624)3.12826005
125chaperone-mediated protein transport (GO:0072321)3.09449707
126DNA ligation (GO:0006266)3.08825592
127histone mRNA metabolic process (GO:0008334)3.08536303
128DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.07980323
129rRNA methylation (GO:0031167)3.03708321
130maturation of 5.8S rRNA (GO:0000460)3.02971983
131establishment of viral latency (GO:0019043)2.99121913
132establishment of protein localization to mitochondrion (GO:0072655)2.95879375
133protein localization to mitochondrion (GO:0070585)2.93490384
134spindle checkpoint (GO:0031577)2.91935958
135protein-cofactor linkage (GO:0018065)2.90245911

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.02853850
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.71493657
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.37513380
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.10482860
5* EST1_17652178_ChIP-ChIP_JURKAT_Human4.07501888
6* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.75531708
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.56577024
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.55016934
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.49164891
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.48825511
11E2F4_17652178_ChIP-ChIP_JURKAT_Human3.41245801
12* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.33678886
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.17088610
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.09764384
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.03371132
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.02177872
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.93655480
18MYC_19030024_ChIP-ChIP_MESCs_Mouse2.90659003
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.88886623
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.83009835
21* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77432969
22VDR_23849224_ChIP-Seq_CD4+_Human2.68215490
23CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.59751532
24MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.58295988
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.44621159
26DCP1A_22483619_ChIP-Seq_HELA_Human2.43673972
27VDR_22108803_ChIP-Seq_LS180_Human2.40248416
28NELFA_20434984_ChIP-Seq_ESCs_Mouse2.35129568
29XRN2_22483619_ChIP-Seq_HELA_Human2.34118742
30THAP11_20581084_ChIP-Seq_MESCs_Mouse2.31508130
31ELK1_19687146_ChIP-ChIP_HELA_Human2.24168279
32E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23721261
33FOXP3_21729870_ChIP-Seq_TREG_Human2.21807389
34ZNF274_21170338_ChIP-Seq_K562_Hela2.18816096
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.05852092
36TTF2_22483619_ChIP-Seq_HELA_Human2.01657064
37* SRF_21415370_ChIP-Seq_HL-1_Mouse2.01536906
38AR_21909140_ChIP-Seq_LNCAP_Human1.99041540
39GABP_19822575_ChIP-Seq_HepG2_Human1.97358053
40FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.95956297
41EWS_26573619_Chip-Seq_HEK293_Human1.93127083
42SALL1_21062744_ChIP-ChIP_HESCs_Human1.92435430
43MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.85234725
44* YY1_21170310_ChIP-Seq_MESCs_Mouse1.82705299
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81642465
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.80280461
47PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.79809609
48POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.79639453
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78081031
50FUS_26573619_Chip-Seq_HEK293_Human1.76974683
51* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76261165
52HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73661710
53HOXB4_20404135_ChIP-ChIP_EML_Mouse1.67180987
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60635150
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.55795277
56* E2F1_21310950_ChIP-Seq_MCF-7_Human1.49679261
57FLI1_27457419_Chip-Seq_LIVER_Mouse1.46849711
58IGF1R_20145208_ChIP-Seq_DFB_Human1.43188111
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.42996086
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.42511568
61POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.38724513
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.36632198
63ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35206821
64KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33738224
65* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.28491852
66TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28119617
67MYC_18940864_ChIP-ChIP_HL60_Human1.27445513
68KDM5A_27292631_Chip-Seq_BREAST_Human1.27318151
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25025041
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21526837
71CIITA_25753668_ChIP-Seq_RAJI_Human1.20698870
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.18928790
73P300_19829295_ChIP-Seq_ESCs_Human1.15417265
74BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14303112
75CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13299878
76TAF15_26573619_Chip-Seq_HEK293_Human1.11651010
77CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.11581718
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09563543
79PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08948942
80RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06692222
81* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05185364
82SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.05135045
83SOX2_18555785_ChIP-Seq_MESCs_Mouse1.04586908
84ZFP57_27257070_Chip-Seq_ESCs_Mouse1.04461800
85EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.02814576
86SOX17_20123909_ChIP-Seq_XEN_Mouse1.01819826
87CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.01291448
88HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.00872954
89MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.99647346
90GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.97421994
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.94898208
92CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92833752
93IRF1_19129219_ChIP-ChIP_H3396_Human0.91993032
94TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.91496805
95CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91353558
96TP53_22573176_ChIP-Seq_HFKS_Human0.90856555
97KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.90359158
98KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.90359158
99KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.90359158
100SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.88786811
101* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87909665
102NOTCH1_21737748_ChIP-Seq_TLL_Human0.87826092
103GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87009182
104KLF4_18555785_ChIP-Seq_MESCs_Mouse0.84167715
105CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.83857639
106TFEB_21752829_ChIP-Seq_HELA_Human0.83127637
107TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.79109056
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.78614323
109* NANOG_19829295_ChIP-Seq_ESCs_Human0.76435401
110* SOX2_19829295_ChIP-Seq_ESCs_Human0.76435401
111NFE2_27457419_Chip-Seq_LIVER_Mouse0.75670252
112FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75278520
113POU5F1_16153702_ChIP-ChIP_HESCs_Human0.74996308
114GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.74823565
115EZH2_27294783_Chip-Seq_NPCs_Mouse0.73646602
116GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.73074436
117PCGF2_27294783_Chip-Seq_NPCs_Mouse0.72885382
118HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.72411045
119NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.70912551
120SPI1_23547873_ChIP-Seq_NB4_Human0.69990175
121NANOG_16153702_ChIP-ChIP_HESCs_Human0.69149532
122STAT3_1855785_ChIP-Seq_MESCs_Mouse0.68324345
123TP63_19390658_ChIP-ChIP_HaCaT_Human0.67701193
124ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.66777020
125SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.66562543
126POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.65604646
127SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.64949896
128SOX2_18692474_ChIP-Seq_MEFs_Mouse0.64843995
129DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.64551051
130SOX2_16153702_ChIP-ChIP_HESCs_Human0.64342479
131SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.64272074
132CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.63474489
133DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.61478783

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.58552118
2MP0004957_abnormal_blastocyst_morpholog4.44478814
3MP0010094_abnormal_chromosome_stability4.37426052
4MP0008057_abnormal_DNA_replication4.05193830
5MP0003111_abnormal_nucleus_morphology4.00688961
6MP0008058_abnormal_DNA_repair3.85370459
7MP0003077_abnormal_cell_cycle3.72033711
8MP0008932_abnormal_embryonic_tissue3.28146736
9MP0003718_maternal_effect2.91692582
10MP0008007_abnormal_cellular_replicative2.90576934
11MP0008877_abnormal_DNA_methylation2.80613023
12MP0003786_premature_aging2.71955011
13MP0001529_abnormal_vocalization2.41611564
14MP0006072_abnormal_retinal_apoptosis2.03232203
15MP0009379_abnormal_foot_pigmentation1.90552029
16MP0001730_embryonic_growth_arrest1.87108281
17MP0003123_paternal_imprinting1.78118201
18MP0003806_abnormal_nucleotide_metabolis1.77994808
19MP0000350_abnormal_cell_proliferation1.73943218
20MP0001986_abnormal_taste_sensitivity1.68200488
21MP0006292_abnormal_olfactory_placode1.63536014
22MP0002396_abnormal_hematopoietic_system1.59896224
23MP0004147_increased_porphyrin_level1.59756819
24MP0002736_abnormal_nociception_after1.55033805
25MP0002210_abnormal_sex_determination1.55015128
26MP0003315_abnormal_perineum_morphology1.51294242
27MP0005084_abnormal_gallbladder_morpholo1.50215120
28MP0006035_abnormal_mitochondrial_morpho1.49959919
29MP0002837_dystrophic_cardiac_calcinosis1.47265925
30MP0003136_yellow_coat_color1.43919169
31MP0002102_abnormal_ear_morphology1.42982086
32MP0006036_abnormal_mitochondrial_physio1.42752683
33MP0003011_delayed_dark_adaptation1.38873325
34MP0001929_abnormal_gametogenesis1.37764978
35MP0003195_calcinosis1.37567717
36MP0002160_abnormal_reproductive_system1.36564553
37MP0001905_abnormal_dopamine_level1.35274002
38MP0001145_abnormal_male_reproductive1.34917734
39MP0003186_abnormal_redox_activity1.29655339
40MP0001697_abnormal_embryo_size1.27876803
41MP0009333_abnormal_splenocyte_physiolog1.26299483
42MP0000313_abnormal_cell_death1.23288388
43MP0000653_abnormal_sex_gland1.21644113
44MP0005253_abnormal_eye_physiology1.18855548
45MP0002080_prenatal_lethality1.15518504
46MP0005380_embryogenesis_phenotype1.14236685
47MP0001672_abnormal_embryogenesis/_devel1.14236685
48MP0008872_abnormal_physiological_respon1.14092892
49MP0003646_muscle_fatigue1.12434539
50MP0003567_abnormal_fetal_cardiomyocyte1.09890982
51MP0009697_abnormal_copulation1.09761133
52MP0005551_abnormal_eye_electrophysiolog1.09526955
53MP0000631_abnormal_neuroendocrine_gland1.09054076
54MP0005499_abnormal_olfactory_system1.08110507
55MP0005394_taste/olfaction_phenotype1.08110507
56MP0002938_white_spotting1.07543240
57MP0001542_abnormal_bone_strength1.06733151
58MP0005389_reproductive_system_phenotype1.05644461
59MP0004215_abnormal_myocardial_fiber1.03257902
60MP0001984_abnormal_olfaction1.02625695
61MP0000372_irregular_coat_pigmentation1.01107834
62MP0002085_abnormal_embryonic_tissue1.00876667
63MP0000566_synostosis1.00287613
64MP0000749_muscle_degeneration0.99975618
65MP0010030_abnormal_orbit_morphology0.99925363
66MP0000647_abnormal_sebaceous_gland0.99209391
67MP0005075_abnormal_melanosome_morpholog0.97884507
68MP0002132_abnormal_respiratory_system0.97874052
69MP0002254_reproductive_system_inflammat0.97351954
70MP0003984_embryonic_growth_retardation0.97210775
71MP0003698_abnormal_male_reproductive0.96325052
72MP0000358_abnormal_cell_content/0.95918120
73MP0002019_abnormal_tumor_incidence0.95910110
74MP0001188_hyperpigmentation0.94201515
75MP0001968_abnormal_touch/_nociception0.93708780
76MP0008995_early_reproductive_senescence0.93261401
77MP0002088_abnormal_embryonic_growth/wei0.91742644
78MP0002233_abnormal_nose_morphology0.91400502
79MP0003119_abnormal_digestive_system0.91234762
80MP0004142_abnormal_muscle_tone0.90423490
81MP0002234_abnormal_pharynx_morphology0.90418257
82MP0000490_abnormal_crypts_of0.89839521
83MP0001727_abnormal_embryo_implantation0.89102741
84MP0004133_heterotaxia0.87735129
85MP0003890_abnormal_embryonic-extraembry0.87427765
86MP0003880_abnormal_central_pattern0.86473252
87MP0005408_hypopigmentation0.85877431
88MP0003121_genomic_imprinting0.83429868
89MP0008789_abnormal_olfactory_epithelium0.82411154
90MP0001119_abnormal_female_reproductive0.82313164
91MP0003937_abnormal_limbs/digits/tail_de0.82087631
92MP0002751_abnormal_autonomic_nervous0.80378723
93MP0001293_anophthalmia0.80127771
94MP0005391_vision/eye_phenotype0.79947133
95MP0002282_abnormal_trachea_morphology0.79635053
96MP0003938_abnormal_ear_development0.77922137
97MP0005410_abnormal_fertilization0.77714032
98MP0006276_abnormal_autonomic_nervous0.77629278
99MP0002095_abnormal_skin_pigmentation0.76717896
100MP0005171_absent_coat_pigmentation0.76448352
101MP0003950_abnormal_plasma_membrane0.74151802
102MP0002163_abnormal_gland_morphology0.74037120
103MP0001324_abnormal_eye_pigmentation0.73912958
104MP0003221_abnormal_cardiomyocyte_apopto0.73131115
105MP0003787_abnormal_imprinting0.72475798
106MP0003941_abnormal_skin_development0.71560123
107MP0001485_abnormal_pinna_reflex0.71261518
108MP0004145_abnormal_muscle_electrophysio0.71021430
109MP0002090_abnormal_vision0.70749703
110MP0009046_muscle_twitch0.69303242
111MP0005395_other_phenotype0.68793670
112MP0002084_abnormal_developmental_patter0.67750705
113MP0002697_abnormal_eye_size0.66964242
114MP0003283_abnormal_digestive_organ0.66959708
115MP0000516_abnormal_urinary_system0.66905486
116MP0005367_renal/urinary_system_phenotyp0.66905486
117MP0000427_abnormal_hair_cycle0.66815528
118MP0002161_abnormal_fertility/fecundity0.66786832
119MP0000703_abnormal_thymus_morphology0.66457850
120MP0008260_abnormal_autophagy0.66367104
121MP0001919_abnormal_reproductive_system0.65816585
122MP0005174_abnormal_tail_pigmentation0.65265713
123MP0002638_abnormal_pupillary_reflex0.64707964
124MP0000689_abnormal_spleen_morphology0.63706787
125MP0001661_extended_life_span0.63541764
126MP0000015_abnormal_ear_pigmentation0.62956084
127MP0003763_abnormal_thymus_physiology0.62628652
128MP0002398_abnormal_bone_marrow0.61220151
129MP0002722_abnormal_immune_system0.59895892
130MP0004197_abnormal_fetal_growth/weight/0.59733591
131MP0002277_abnormal_respiratory_mucosa0.58321610
132MP0001764_abnormal_homeostasis0.58216136
133MP0005384_cellular_phenotype0.57215073
134MP0001286_abnormal_eye_development0.56260432
135MP0000049_abnormal_middle_ear0.56236334
136MP0001853_heart_inflammation0.55129671

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.68330847
2Breast hypoplasia (HP:0003187)4.28677985
3Acute necrotizing encephalopathy (HP:0006965)4.10611672
4Abnormality of cells of the erythroid lineage (HP:0012130)4.02917061
5Cerebral hypomyelination (HP:0006808)3.97638108
6Mitochondrial inheritance (HP:0001427)3.80986372
7Abnormal number of erythroid precursors (HP:0012131)3.73047181
8Increased hepatocellular lipid droplets (HP:0006565)3.64315537
9Carpal bone hypoplasia (HP:0001498)3.57779058
10Abnormal mitochondria in muscle tissue (HP:0008316)3.55205922
11Increased serum pyruvate (HP:0003542)3.50244886
12Abnormality of glycolysis (HP:0004366)3.50244886
13Increased CSF lactate (HP:0002490)3.47874096
14Reticulocytopenia (HP:0001896)3.47863226
15Hepatocellular necrosis (HP:0001404)3.38103804
163-Methylglutaconic aciduria (HP:0003535)3.36510887
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.32325141
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.31826513
19Rough bone trabeculation (HP:0100670)3.30702420
20Progressive macrocephaly (HP:0004481)3.27154044
21Macrocytic anemia (HP:0001972)3.16371736
22Colon cancer (HP:0003003)3.15683017
23Cerebral edema (HP:0002181)3.14066734
24Acute encephalopathy (HP:0006846)3.12388098
25Lipid accumulation in hepatocytes (HP:0006561)3.03043553
26Patellar aplasia (HP:0006443)3.00155788
27Increased serum lactate (HP:0002151)2.92422078
28Methylmalonic acidemia (HP:0002912)2.88493791
29Aplasia/Hypoplasia of the patella (HP:0006498)2.86633631
30Oral leukoplakia (HP:0002745)2.86497328
31Renal Fanconi syndrome (HP:0001994)2.78011907
32Aplastic anemia (HP:0001915)2.71571001
33Hepatic necrosis (HP:0002605)2.71319567
34Exertional dyspnea (HP:0002875)2.64488291
35Irregular epiphyses (HP:0010582)2.60225271
36Meckel diverticulum (HP:0002245)2.57766201
37Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.57468333
38Absent radius (HP:0003974)2.55737672
39Pallor (HP:0000980)2.53813245
40Abnormality of the preputium (HP:0100587)2.51448434
41Decreased activity of mitochondrial respiratory chain (HP:0008972)2.51174644
42Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.51174644
43Abnormal trabecular bone morphology (HP:0100671)2.47473453
44Abnormality of the ileum (HP:0001549)2.47346241
45Methylmalonic aciduria (HP:0012120)2.45636250
46Chromsome breakage (HP:0040012)2.44475729
47Hypoplasia of the capital femoral epiphysis (HP:0003090)2.43802850
48Molar tooth sign on MRI (HP:0002419)2.43127635
49Abnormality of midbrain morphology (HP:0002418)2.43127635
50Abnormality of the labia minora (HP:0012880)2.42910735
51Septo-optic dysplasia (HP:0100842)2.41431261
52Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.40964198
53Type I transferrin isoform profile (HP:0003642)2.39865186
54Exercise intolerance (HP:0003546)2.39120913
55Premature graying of hair (HP:0002216)2.38849695
56Horseshoe kidney (HP:0000085)2.38123690
57Abnormality of the anterior horn cell (HP:0006802)2.37714873
58Degeneration of anterior horn cells (HP:0002398)2.37714873
59Abnormal lung lobation (HP:0002101)2.37426252
60Aplasia involving forearm bones (HP:0009822)2.36478089
61Absent forearm bone (HP:0003953)2.36478089
62Stenosis of the external auditory canal (HP:0000402)2.36304875
63Parakeratosis (HP:0001036)2.33966515
64Chromosomal breakage induced by crosslinking agents (HP:0003221)2.32220494
65Respiratory difficulties (HP:0002880)2.30663192
66Pancreatic fibrosis (HP:0100732)2.29949626
67Secondary amenorrhea (HP:0000869)2.29213413
68Leukodystrophy (HP:0002415)2.27048658
69CNS hypomyelination (HP:0003429)2.25126430
70Hyperglycinemia (HP:0002154)2.23702999
71Abnormality of serum amino acid levels (HP:0003112)2.23381415
72Abnormality of chromosome stability (HP:0003220)2.22589861
73Respiratory failure (HP:0002878)2.21942159
74Abnormality of methionine metabolism (HP:0010901)2.20437268
75Aplasia/Hypoplasia involving the musculature (HP:0001460)2.17657091
76Calf muscle hypertrophy (HP:0008981)2.17585982
77Triphalangeal thumb (HP:0001199)2.16494983
78Impulsivity (HP:0100710)2.15511923
79Hyperalaninemia (HP:0003348)2.14723870
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.14723870
81Abnormality of alanine metabolism (HP:0010916)2.14723870
82Volvulus (HP:0002580)2.13869072
83Increased intramyocellular lipid droplets (HP:0012240)2.10915776
84Nephronophthisis (HP:0000090)2.08912917
85Abnormality of the duodenum (HP:0002246)2.08002912
86Microretrognathia (HP:0000308)2.07382121
87Bone marrow hypocellularity (HP:0005528)2.06767828
88Absent epiphyses (HP:0010577)2.05257056
89Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.05257056
90Aplasia/Hypoplasia of the uvula (HP:0010293)2.04682439
91Microvesicular hepatic steatosis (HP:0001414)2.04026389
92Absent thumb (HP:0009777)2.04003387
93Abnormality of aspartate family amino acid metabolism (HP:0010899)2.03945912
94Small intestinal stenosis (HP:0012848)2.03413340
95Duodenal stenosis (HP:0100867)2.03413340
96Lactic acidosis (HP:0003128)2.03282181
97Postnatal microcephaly (HP:0005484)2.03208563
98Abnormality of the heme biosynthetic pathway (HP:0010472)2.02316683
99Cleft eyelid (HP:0000625)2.01841673
100Renal cortical cysts (HP:0000803)2.00261656
101Abnormality of the umbilical cord (HP:0010881)1.98037075
102True hermaphroditism (HP:0010459)1.97940073
103Optic disc pallor (HP:0000543)1.96621329
104Poor head control (HP:0002421)1.96595922
10511 pairs of ribs (HP:0000878)1.95595496
106Muscle hypertrophy of the lower extremities (HP:0008968)1.94266635
107Supernumerary spleens (HP:0009799)1.93534336
108Ependymoma (HP:0002888)1.93121956
109Lethargy (HP:0001254)1.92789839
110CNS demyelination (HP:0007305)1.92038458
111Absent septum pellucidum (HP:0001331)1.91949200
112Aplasia/Hypoplasia of the sacrum (HP:0008517)1.91473294
113Intestinal atresia (HP:0011100)1.91311701
114Duplicated collecting system (HP:0000081)1.88982792
115Cellular immunodeficiency (HP:0005374)1.88961097
116Hypoplasia of the pons (HP:0012110)1.88225026
117Bilateral microphthalmos (HP:0007633)1.87715483
118Sparse eyelashes (HP:0000653)1.87371342
119Pancytopenia (HP:0001876)1.87346703
120Abnormality of the pons (HP:0007361)1.87305254
121Pendular nystagmus (HP:0012043)1.85870853
122Abnormal spermatogenesis (HP:0008669)1.85571359
123Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.83812678
124Abnormal protein N-linked glycosylation (HP:0012347)1.83812678
125Abnormal protein glycosylation (HP:0012346)1.83812678
126Abnormal glycosylation (HP:0012345)1.83812678
127Sclerocornea (HP:0000647)1.82891937
128Type 2 muscle fiber atrophy (HP:0003554)1.82437150
129Small hand (HP:0200055)1.82344942
130Ectopic kidney (HP:0000086)1.81437192
131Premature ovarian failure (HP:0008209)1.80993689
132Megaloblastic anemia (HP:0001889)1.79908084
133Congenital, generalized hypertrichosis (HP:0004540)1.79410045
134Sloping forehead (HP:0000340)1.78939505
135Pancreatic cysts (HP:0001737)1.78789400
136Amniotic constriction ring (HP:0009775)1.78001984
137Abnormality of placental membranes (HP:0011409)1.78001984
138Exercise-induced muscle cramps (HP:0003710)1.76319467
139Abnormality of renal resorption (HP:0011038)1.75910081
140Abnormal number of incisors (HP:0011064)1.71892755
141Abnormality of the septum pellucidum (HP:0007375)1.71421789

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.05371528
2WEE14.04320939
3VRK23.69699138
4STK163.57503196
5EIF2AK13.57193588
6SRPK13.03369663
7NME22.65912761
8CDC72.61007399
9PLK42.60903993
10PBK2.56089734
11VRK12.44309765
12BRSK22.43363072
13TRIM282.26669130
14EIF2AK32.22497690
15MKNK12.21128664
16TSSK62.11694246
17TAF12.05923555
18WNK31.97904769
19TESK21.86060595
20PLK31.82756914
21CCNB11.80055454
22ACVR1B1.77361366
23PLK11.71591124
24TLK11.61318130
25MKNK21.59070366
26TTK1.55873591
27NEK11.53969360
28MAP4K21.52988302
29FRK1.44364545
30MST41.43041371
31BRSK11.40961363
32ZAK1.32474192
33AURKA1.31045039
34PIM21.30905453
35NEK21.30599302
36AURKB1.27446855
37PNCK1.25930138
38NME11.25669674
39DYRK31.19491478
40BCR1.15694076
41LIMK11.14407367
42CHEK21.11798275
43DYRK21.05925488
44BRAF1.03021194
45EIF2AK21.01176782
46CDK71.01079326
47ATR1.00174230
48GRK10.95133049
49MUSK0.92561316
50EPHA20.89316898
51CSNK1G10.85255843
52BCKDK0.84471348
53INSRR0.82067232
54STK390.78756623
55CSNK2A10.75762706
56CHEK10.75626675
57CDK80.75164425
58ARAF0.74754907
59CSNK1G20.74448893
60STK40.74054117
61TESK10.71283376
62STK30.71129379
63CSNK2A20.70162842
64KDR0.69144458
65PAK10.67696859
66AKT30.66883944
67ABL20.66301558
68RPS6KA50.65810064
69BMPR1B0.64576452
70CLK10.63895133
71ADRBK20.63535224
72OXSR10.62775175
73PASK0.62470939
74MAP3K80.62341916
75IRAK40.60205791
76CDK190.59067542
77PRKCG0.58217464
78NEK60.57537320
79RPS6KB20.57255941
80TNIK0.56788864
81PLK20.55992598
82CSNK1G30.55410796
83ATM0.54509022
84NUAK10.53023567
85MAP3K40.50449313
86TGFBR10.50243944
87RPS6KA40.49046032
88CSNK1A1L0.47655117
89CDK10.46846232
90CASK0.46087929
91IRAK30.45701614
92CDK20.45414826
93YES10.45027447
94STK38L0.44707937
95MAP2K70.44341075
96DAPK10.42906587
97PAK40.40817935
98GRK70.40643239
99TEC0.40090619
100PDK40.39408506
101PDK30.39408506
102CDK140.39212776
103PRKCI0.38097206
104TIE10.37208125
105PRKCE0.35662888
106CSNK1E0.33922676
107MAPKAPK50.33564281
108ALK0.33464814
109PIM10.33128949
110ERBB40.32674164
111MAP3K120.32409688
112ERBB30.31962791
113IRAK20.31759853
114ADRBK10.31042569
115MELK0.30939318
116STK100.30620652
117UHMK10.30554044
118TXK0.30222779
119MAPK130.29902518
120PRKDC0.29545988
121CDK11A0.29175862
122CDK180.28602701
123PINK10.28493449
124FGFR10.28061749
125PDK20.27997959
126CDK40.27077090
127PRKACB0.26407086
128STK240.26373194
129CDK150.26008199
130CSNK1A10.25291202
131CSNK1D0.25239260
132WNK40.24897625
133GRK50.22378646

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.92509570
2RNA polymerase_Homo sapiens_hsa030204.14819374
3Ribosome_Homo sapiens_hsa030104.09752426
4DNA replication_Homo sapiens_hsa030303.98610389
5Mismatch repair_Homo sapiens_hsa034303.50365036
6* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.39015052
7Spliceosome_Homo sapiens_hsa030403.03587477
8Homologous recombination_Homo sapiens_hsa034402.95563843
9Nucleotide excision repair_Homo sapiens_hsa034202.85133257
10Pyrimidine metabolism_Homo sapiens_hsa002402.62160579
11* RNA transport_Homo sapiens_hsa030132.59782711
12Oxidative phosphorylation_Homo sapiens_hsa001902.50815720
13Base excision repair_Homo sapiens_hsa034102.39482451
14Basal transcription factors_Homo sapiens_hsa030222.36462369
15Protein export_Homo sapiens_hsa030602.33464499
16Parkinsons disease_Homo sapiens_hsa050122.24516334
17Fanconi anemia pathway_Homo sapiens_hsa034602.16557457
18Cell cycle_Homo sapiens_hsa041102.13850556
19Non-homologous end-joining_Homo sapiens_hsa034501.93604550
20Huntingtons disease_Homo sapiens_hsa050161.89977387
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.86740001
22RNA degradation_Homo sapiens_hsa030181.69568812
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.66758919
24Purine metabolism_Homo sapiens_hsa002301.57198900
25Vitamin B6 metabolism_Homo sapiens_hsa007501.54687721
26Propanoate metabolism_Homo sapiens_hsa006401.54250590
27One carbon pool by folate_Homo sapiens_hsa006701.44410079
28Selenocompound metabolism_Homo sapiens_hsa004501.40897550
29Alzheimers disease_Homo sapiens_hsa050101.37593826
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.36406598
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.17658729
32p53 signaling pathway_Homo sapiens_hsa041151.16981992
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.16701851
34Epstein-Barr virus infection_Homo sapiens_hsa051691.16533269
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.14320125
36mRNA surveillance pathway_Homo sapiens_hsa030151.11244588
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.09217253
38Oocyte meiosis_Homo sapiens_hsa041140.88905567
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87171487
40Systemic lupus erythematosus_Homo sapiens_hsa053220.85417590
41Butanoate metabolism_Homo sapiens_hsa006500.75775178
42Glutathione metabolism_Homo sapiens_hsa004800.75620289
43Tryptophan metabolism_Homo sapiens_hsa003800.74395041
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70913975
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.68491398
46Steroid biosynthesis_Homo sapiens_hsa001000.66867113
47Peroxisome_Homo sapiens_hsa041460.66144544
48Arachidonic acid metabolism_Homo sapiens_hsa005900.65712432
49Folate biosynthesis_Homo sapiens_hsa007900.61863868
50Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61768124
51Cardiac muscle contraction_Homo sapiens_hsa042600.60610003
52Pentose phosphate pathway_Homo sapiens_hsa000300.59799143
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.59734999
54beta-Alanine metabolism_Homo sapiens_hsa004100.57428861
55SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57318463
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57223291
57Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56872775
58Metabolic pathways_Homo sapiens_hsa011000.54816483
59Nitrogen metabolism_Homo sapiens_hsa009100.53831174
60Caffeine metabolism_Homo sapiens_hsa002320.53268896
61Ether lipid metabolism_Homo sapiens_hsa005650.51316812
62Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51278904
63Sulfur metabolism_Homo sapiens_hsa009200.49539001
64Fatty acid elongation_Homo sapiens_hsa000620.49316845
65Viral carcinogenesis_Homo sapiens_hsa052030.48332085
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.46098131
67Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45760422
68Linoleic acid metabolism_Homo sapiens_hsa005910.45726445
69Regulation of autophagy_Homo sapiens_hsa041400.45148917
70Primary immunodeficiency_Homo sapiens_hsa053400.44642992
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.43941544
72Herpes simplex infection_Homo sapiens_hsa051680.40137147
73Collecting duct acid secretion_Homo sapiens_hsa049660.39910392
74Nicotine addiction_Homo sapiens_hsa050330.39714655
75Allograft rejection_Homo sapiens_hsa053300.39663369
76Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.38664185
77Fatty acid degradation_Homo sapiens_hsa000710.38109058
78Chemical carcinogenesis_Homo sapiens_hsa052040.37603902
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36906264
80Sphingolipid metabolism_Homo sapiens_hsa006000.36896230
81Antigen processing and presentation_Homo sapiens_hsa046120.35761300
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35646133
83Vitamin digestion and absorption_Homo sapiens_hsa049770.35376757
84Retinol metabolism_Homo sapiens_hsa008300.35002805
85Basal cell carcinoma_Homo sapiens_hsa052170.34626796
86Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.34269055
87Autoimmune thyroid disease_Homo sapiens_hsa053200.34117400
88Drug metabolism - other enzymes_Homo sapiens_hsa009830.33385349
89Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.33030496
90Alcoholism_Homo sapiens_hsa050340.32904608
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30983800
92Biosynthesis of amino acids_Homo sapiens_hsa012300.30898099
93Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30745233
94Hedgehog signaling pathway_Homo sapiens_hsa043400.25041660
95Phototransduction_Homo sapiens_hsa047440.24462722
96Asthma_Homo sapiens_hsa053100.24178370
97Olfactory transduction_Homo sapiens_hsa047400.23243039
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.23092028
99HTLV-I infection_Homo sapiens_hsa051660.23027275
100Rheumatoid arthritis_Homo sapiens_hsa053230.22814348
101Vibrio cholerae infection_Homo sapiens_hsa051100.22714544
102N-Glycan biosynthesis_Homo sapiens_hsa005100.22507954
103Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.22093006
104Fatty acid metabolism_Homo sapiens_hsa012120.21771121
105Maturity onset diabetes of the young_Homo sapiens_hsa049500.20607518
106alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.19668176
107Fructose and mannose metabolism_Homo sapiens_hsa000510.19656548
108Carbon metabolism_Homo sapiens_hsa012000.19099883
109Wnt signaling pathway_Homo sapiens_hsa043100.19002604
110Taste transduction_Homo sapiens_hsa047420.17592898
111Primary bile acid biosynthesis_Homo sapiens_hsa001200.17157173
112Cyanoamino acid metabolism_Homo sapiens_hsa004600.16006541
113Shigellosis_Homo sapiens_hsa051310.15560460
114Phagosome_Homo sapiens_hsa041450.14648230
115Intestinal immune network for IgA production_Homo sapiens_hsa046720.13784417
116Graft-versus-host disease_Homo sapiens_hsa053320.13632172
117Sulfur relay system_Homo sapiens_hsa041220.13619538
118Hematopoietic cell lineage_Homo sapiens_hsa046400.11642950
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.11266520
120Legionellosis_Homo sapiens_hsa051340.11205290
121Arginine and proline metabolism_Homo sapiens_hsa003300.10254318
122Pyruvate metabolism_Homo sapiens_hsa006200.07044969
123Type I diabetes mellitus_Homo sapiens_hsa049400.07011892
124Thyroid cancer_Homo sapiens_hsa052160.05594392
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.05515846
126Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.03470899
127Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.02823036
128TGF-beta signaling pathway_Homo sapiens_hsa043500.02621390
129Apoptosis_Homo sapiens_hsa042100.01654740
130NOD-like receptor signaling pathway_Homo sapiens_hsa046210.01614524
131Measles_Homo sapiens_hsa05162-0.0283443
132Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060-0.0232920
133Hippo signaling pathway_Homo sapiens_hsa04390-0.0228073

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