Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 5.90907661 |
2 | maturation of SSU-rRNA (GO:0030490) | 5.31498137 |
3 | DNA deamination (GO:0045006) | 5.03819191 |
4 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.75683214 |
5 | proteasome assembly (GO:0043248) | 4.66811181 |
6 | ribosomal small subunit biogenesis (GO:0042274) | 4.63692514 |
7 | ribosomal large subunit biogenesis (GO:0042273) | 4.58347050 |
8 | respiratory chain complex IV assembly (GO:0008535) | 4.56242561 |
9 | rRNA modification (GO:0000154) | 4.46512513 |
10 | termination of RNA polymerase III transcription (GO:0006386) | 4.38583373 |
11 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.38583373 |
12 | viral transcription (GO:0019083) | 4.36379640 |
13 | cytochrome complex assembly (GO:0017004) | 4.34647866 |
14 | translational termination (GO:0006415) | 4.31323078 |
15 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.21490953 |
16 | purine nucleobase biosynthetic process (GO:0009113) | 4.19862011 |
17 | 7-methylguanosine mRNA capping (GO:0006370) | 4.14189235 |
18 | termination of RNA polymerase I transcription (GO:0006363) | 4.13922346 |
19 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 4.13646797 |
20 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.10232189 |
21 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.09959581 |
22 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 4.09591854 |
23 | 7-methylguanosine RNA capping (GO:0009452) | 4.06681594 |
24 | RNA capping (GO:0036260) | 4.06681594 |
25 | cotranslational protein targeting to membrane (GO:0006613) | 4.05844318 |
26 | nucleobase biosynthetic process (GO:0046112) | 4.03688858 |
27 | protein targeting to ER (GO:0045047) | 4.00714656 |
28 | ribosome biogenesis (GO:0042254) | 3.97620923 |
29 | rRNA processing (GO:0006364) | 3.97314005 |
30 | formation of translation preinitiation complex (GO:0001731) | 3.93695000 |
31 | translational elongation (GO:0006414) | 3.88497273 |
32 | transcription from RNA polymerase I promoter (GO:0006360) | 3.88249009 |
33 | protein localization to endoplasmic reticulum (GO:0070972) | 3.87859883 |
34 | pseudouridine synthesis (GO:0001522) | 3.86393776 |
35 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.85473642 |
36 | rRNA metabolic process (GO:0016072) | 3.83245947 |
37 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.80766646 |
38 | translational initiation (GO:0006413) | 3.78663536 |
39 | rRNA methylation (GO:0031167) | 3.77878583 |
40 | ribosome assembly (GO:0042255) | 3.77767157 |
41 | cellular component biogenesis (GO:0044085) | 3.72438905 |
42 | DNA strand elongation (GO:0022616) | 3.72258092 |
43 | protein-cofactor linkage (GO:0018065) | 3.72138336 |
44 | translation (GO:0006412) | 3.71665911 |
45 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.71278283 |
46 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.69828829 |
47 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.69646248 |
48 | peptidyl-histidine modification (GO:0018202) | 3.63756752 |
49 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.61326932 |
50 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.61326932 |
51 | L-methionine biosynthetic process (GO:0071265) | 3.58833007 |
52 | amino acid salvage (GO:0043102) | 3.58833007 |
53 | L-methionine salvage (GO:0071267) | 3.58833007 |
54 | establishment of integrated proviral latency (GO:0075713) | 3.58475369 |
55 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.58324818 |
56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.57018826 |
57 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.55758115 |
58 | CENP-A containing nucleosome assembly (GO:0034080) | 3.55653823 |
59 | ubiquinone biosynthetic process (GO:0006744) | 3.55259405 |
60 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.54227294 |
61 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.54093029 |
62 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.51776748 |
63 | chromatin remodeling at centromere (GO:0031055) | 3.49934827 |
64 | maturation of 5.8S rRNA (GO:0000460) | 3.49071372 |
65 | * tRNA processing (GO:0008033) | 3.45997048 |
66 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.44465131 |
67 | mitotic metaphase plate congression (GO:0007080) | 3.43655010 |
68 | cellular protein complex disassembly (GO:0043624) | 3.41635619 |
69 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.41087907 |
70 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.40698100 |
71 | negative regulation of ligase activity (GO:0051352) | 3.40698100 |
72 | DNA replication initiation (GO:0006270) | 3.40351032 |
73 | electron transport chain (GO:0022900) | 3.40189141 |
74 | mannosylation (GO:0097502) | 3.40169633 |
75 | respiratory electron transport chain (GO:0022904) | 3.40008666 |
76 | viral life cycle (GO:0019058) | 3.39473128 |
77 | telomere maintenance via recombination (GO:0000722) | 3.38421472 |
78 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.35692236 |
79 | spliceosomal snRNP assembly (GO:0000387) | 3.35086761 |
80 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.34633542 |
81 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.34503198 |
82 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.34503198 |
83 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.33873490 |
84 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.32441680 |
85 | IMP biosynthetic process (GO:0006188) | 3.30893889 |
86 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.30804268 |
87 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.28556989 |
88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.28556989 |
89 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.28383210 |
90 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.28383210 |
91 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.28383210 |
92 | regulation of mitochondrial translation (GO:0070129) | 3.27359559 |
93 | protein neddylation (GO:0045116) | 3.25308350 |
94 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.24887170 |
95 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.24887170 |
96 | NADH dehydrogenase complex assembly (GO:0010257) | 3.24887170 |
97 | telomere maintenance via telomere lengthening (GO:0010833) | 3.21957996 |
98 | DNA replication checkpoint (GO:0000076) | 3.20199080 |
99 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.20186396 |
100 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.20186396 |
101 | ubiquinone metabolic process (GO:0006743) | 3.20166951 |
102 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.20127868 |
103 | protein complex biogenesis (GO:0070271) | 3.19319162 |
104 | chaperone-mediated protein transport (GO:0072321) | 3.17425187 |
105 | DNA-templated transcription, elongation (GO:0006354) | 3.15844792 |
106 | protein targeting to mitochondrion (GO:0006626) | 3.15604005 |
107 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.14933817 |
108 | ATP synthesis coupled proton transport (GO:0015986) | 3.14764433 |
109 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.14764433 |
110 | tRNA modification (GO:0006400) | 3.14272786 |
111 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.13527248 |
112 | protein K6-linked ubiquitination (GO:0085020) | 3.12516527 |
113 | GTP biosynthetic process (GO:0006183) | 3.12317782 |
114 | * ncRNA processing (GO:0034470) | 3.10385424 |
115 | establishment of protein localization to mitochondrion (GO:0072655) | 3.10048392 |
116 | iron-sulfur cluster assembly (GO:0016226) | 3.10022522 |
117 | metallo-sulfur cluster assembly (GO:0031163) | 3.10022522 |
118 | cullin deneddylation (GO:0010388) | 3.08277806 |
119 | protein deneddylation (GO:0000338) | 3.08061081 |
120 | positive regulation of ligase activity (GO:0051351) | 3.06180020 |
121 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.00243476 |
122 | male meiosis I (GO:0007141) | 2.98878505 |
123 | * tRNA metabolic process (GO:0006399) | 2.97403503 |
124 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.96988137 |
125 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.95359326 |
126 | isotype switching (GO:0045190) | 2.95359326 |
127 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.95359326 |
128 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.87694190 |
129 | protein localization to mitochondrion (GO:0070585) | 2.86644870 |
130 | * ncRNA metabolic process (GO:0034660) | 2.86217612 |
131 | transcription from mitochondrial promoter (GO:0006390) | 2.85862494 |
132 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.85683903 |
133 | base-excision repair, AP site formation (GO:0006285) | 2.77946173 |
134 | tRNA methylation (GO:0030488) | 2.77843082 |
135 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.73293369 |
136 | DNA double-strand break processing (GO:0000729) | 2.72645882 |
137 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.72424699 |
138 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.72424699 |
139 | UTP biosynthetic process (GO:0006228) | 2.69036908 |
140 | quinone biosynthetic process (GO:1901663) | 2.68866376 |
141 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.68784212 |
142 | RNA modification (GO:0009451) | 2.65384006 |
143 | recombinational repair (GO:0000725) | 2.63437856 |
144 | double-strand break repair via homologous recombination (GO:0000724) | 2.62726146 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.31951877 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.65139660 |
3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.37905112 |
4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21330182 |
5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.00233411 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.97076580 |
7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.60025788 |
8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.30565503 |
9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.21330717 |
10 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.12505401 |
11 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.04697127 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.02496361 |
13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.99514176 |
14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.96402593 |
15 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.93303239 |
16 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.89580252 |
17 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.89326509 |
18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.84897392 |
19 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.79676609 |
20 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.79142965 |
21 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.76653752 |
22 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.76225541 |
23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.66569697 |
24 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.49548663 |
25 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.44889237 |
26 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.40117885 |
27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.39390967 |
28 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.36862487 |
29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.34753094 |
30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.27752000 |
31 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.24892636 |
32 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.24078991 |
33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.22002187 |
34 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.12882615 |
35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.11412358 |
36 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.10124541 |
37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06429087 |
38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.96314833 |
39 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.94691957 |
40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.90640673 |
41 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.90384377 |
42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.87927761 |
43 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.86025311 |
44 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.78557294 |
45 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.76949459 |
46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74883257 |
47 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.74691207 |
48 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.74016007 |
49 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.69580972 |
50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.67805784 |
51 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.58842925 |
52 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58835182 |
53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57177313 |
54 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.50533107 |
55 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.43914168 |
56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.43093171 |
57 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.38481812 |
58 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37810945 |
59 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.37539922 |
60 | VDR_22108803_ChIP-Seq_LS180_Human | 1.36913012 |
61 | * TP53_22573176_ChIP-Seq_HFKS_Human | 1.36487102 |
62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.35345781 |
63 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33063506 |
64 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.31137077 |
65 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.27677437 |
66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.26064528 |
67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.24048928 |
68 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.22892546 |
69 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.19629816 |
70 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18621825 |
71 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.13040414 |
72 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.09235906 |
73 | EWS_26573619_Chip-Seq_HEK293_Human | 1.07039877 |
74 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.04354387 |
75 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03501518 |
76 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.01354714 |
77 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00828172 |
78 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.97471627 |
79 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.95876897 |
80 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.94969716 |
81 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92314831 |
82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.91322686 |
83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.91322686 |
84 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.90724478 |
85 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90591738 |
86 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.89889048 |
87 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.88772402 |
88 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.88688624 |
89 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.87881723 |
90 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87518015 |
91 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.86438388 |
92 | * EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.86397847 |
93 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.85855338 |
94 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.85303058 |
95 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82967289 |
96 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.82898358 |
97 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.82457140 |
98 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.82379307 |
99 | * ERA_21632823_ChIP-Seq_H3396_Human | 0.82319008 |
100 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.81999879 |
101 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.81855264 |
102 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.81665645 |
103 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.81219948 |
104 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.80815560 |
105 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.80503225 |
106 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.80202398 |
107 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.79759947 |
108 | GATA3_26560356_Chip-Seq_TH2_Human | 0.79289667 |
109 | NCOR_22424771_ChIP-Seq_293T_Human | 0.79019914 |
110 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77361500 |
111 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.76584535 |
112 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.76368857 |
113 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.75030111 |
114 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.73826414 |
115 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.71989851 |
116 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.70331121 |
117 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.69615738 |
118 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.69035587 |
119 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.68265418 |
120 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.67708057 |
121 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.66717593 |
122 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.65300099 |
123 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.65139674 |
124 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.63907373 |
125 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.63601718 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.65803470 |
2 | MP0008057_abnormal_DNA_replication | 4.37093633 |
3 | MP0010094_abnormal_chromosome_stability | 4.32716443 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.25329589 |
5 | MP0008058_abnormal_DNA_repair | 4.21333288 |
6 | MP0003111_abnormal_nucleus_morphology | 3.83477642 |
7 | MP0003077_abnormal_cell_cycle | 3.52958058 |
8 | MP0003718_maternal_effect | 2.82881208 |
9 | MP0008877_abnormal_DNA_methylation | 2.72693250 |
10 | MP0003123_paternal_imprinting | 2.69206325 |
11 | MP0002396_abnormal_hematopoietic_system | 2.60902279 |
12 | MP0008932_abnormal_embryonic_tissue | 2.60868278 |
13 | MP0008007_abnormal_cellular_replicative | 2.60330801 |
14 | MP0003806_abnormal_nucleotide_metabolis | 2.56894153 |
15 | MP0009379_abnormal_foot_pigmentation | 2.46975838 |
16 | MP0003786_premature_aging | 2.16112166 |
17 | MP0003195_calcinosis | 2.15170064 |
18 | MP0008875_abnormal_xenobiotic_pharmacok | 2.11476854 |
19 | MP0003315_abnormal_perineum_morphology | 1.99568318 |
20 | MP0003186_abnormal_redox_activity | 1.97531978 |
21 | MP0006292_abnormal_olfactory_placode | 1.84889461 |
22 | MP0005645_abnormal_hypothalamus_physiol | 1.75835164 |
23 | MP0008789_abnormal_olfactory_epithelium | 1.73986110 |
24 | MP0002210_abnormal_sex_determination | 1.73133638 |
25 | MP0001929_abnormal_gametogenesis | 1.66409442 |
26 | MP0005084_abnormal_gallbladder_morpholo | 1.66382917 |
27 | MP0001730_embryonic_growth_arrest | 1.65611102 |
28 | MP0006036_abnormal_mitochondrial_physio | 1.63730232 |
29 | MP0003787_abnormal_imprinting | 1.58735015 |
30 | MP0009333_abnormal_splenocyte_physiolog | 1.51514986 |
31 | MP0002837_dystrophic_cardiac_calcinosis | 1.51279094 |
32 | MP0001145_abnormal_male_reproductive | 1.49713891 |
33 | MP0002095_abnormal_skin_pigmentation | 1.47108028 |
34 | MP0000350_abnormal_cell_proliferation | 1.46552897 |
35 | MP0002876_abnormal_thyroid_physiology | 1.44886008 |
36 | MP0000015_abnormal_ear_pigmentation | 1.44833342 |
37 | MP0005551_abnormal_eye_electrophysiolog | 1.40681172 |
38 | MP0000653_abnormal_sex_gland | 1.40170592 |
39 | MP0008872_abnormal_physiological_respon | 1.39949698 |
40 | MP0001984_abnormal_olfaction | 1.36103053 |
41 | MP0005253_abnormal_eye_physiology | 1.35757639 |
42 | MP0006035_abnormal_mitochondrial_morpho | 1.35068972 |
43 | MP0001529_abnormal_vocalization | 1.34961155 |
44 | MP0005075_abnormal_melanosome_morpholog | 1.34433042 |
45 | MP0002254_reproductive_system_inflammat | 1.32218067 |
46 | MP0000313_abnormal_cell_death | 1.31263041 |
47 | MP0004147_increased_porphyrin_level | 1.28711123 |
48 | MP0002938_white_spotting | 1.26826837 |
49 | MP0005646_abnormal_pituitary_gland | 1.25693595 |
50 | MP0002132_abnormal_respiratory_system | 1.25043659 |
51 | MP0003763_abnormal_thymus_physiology | 1.21870940 |
52 | MP0001986_abnormal_taste_sensitivity | 1.18364946 |
53 | MP0009697_abnormal_copulation | 1.16561680 |
54 | MP0001905_abnormal_dopamine_level | 1.15554075 |
55 | MP0000490_abnormal_crypts_of | 1.15347714 |
56 | MP0005389_reproductive_system_phenotype | 1.14577751 |
57 | MP0001697_abnormal_embryo_size | 1.13999633 |
58 | MP0004808_abnormal_hematopoietic_stem | 1.13221415 |
59 | MP0001188_hyperpigmentation | 1.12662724 |
60 | MP0003011_delayed_dark_adaptation | 1.10221436 |
61 | MP0000427_abnormal_hair_cycle | 1.10092001 |
62 | MP0000465_gastrointestinal_hemorrhage | 1.08422447 |
63 | MP0000358_abnormal_cell_content/ | 1.08047207 |
64 | MP0005409_darkened_coat_color | 1.06994429 |
65 | MP0000631_abnormal_neuroendocrine_gland | 1.06208202 |
66 | MP0002163_abnormal_gland_morphology | 1.05380681 |
67 | MP0004043_abnormal_pH_regulation | 1.05071316 |
68 | MP0002019_abnormal_tumor_incidence | 1.04705503 |
69 | MP0003136_yellow_coat_color | 1.03868295 |
70 | MP0002102_abnormal_ear_morphology | 1.03294928 |
71 | MP0003698_abnormal_male_reproductive | 1.02091220 |
72 | MP0001919_abnormal_reproductive_system | 1.01479924 |
73 | MP0005410_abnormal_fertilization | 1.00551568 |
74 | MP0002080_prenatal_lethality | 0.98152313 |
75 | MP0001764_abnormal_homeostasis | 0.97625214 |
76 | MP0008995_early_reproductive_senescence | 0.97617187 |
77 | MP0005394_taste/olfaction_phenotype | 0.96846638 |
78 | MP0005499_abnormal_olfactory_system | 0.96846638 |
79 | MP0001119_abnormal_female_reproductive | 0.96212945 |
80 | MP0003646_muscle_fatigue | 0.96193648 |
81 | MP0005379_endocrine/exocrine_gland_phen | 0.96096561 |
82 | MP0001672_abnormal_embryogenesis/_devel | 0.93583238 |
83 | MP0005380_embryogenesis_phenotype | 0.93583238 |
84 | MP0005408_hypopigmentation | 0.93141393 |
85 | MP0009046_muscle_twitch | 0.90332777 |
86 | MP0000372_irregular_coat_pigmentation | 0.89182239 |
87 | MP0005332_abnormal_amino_acid | 0.89086888 |
88 | MP0002160_abnormal_reproductive_system | 0.88881337 |
89 | MP0001485_abnormal_pinna_reflex | 0.88678716 |
90 | MP0008260_abnormal_autophagy | 0.88605274 |
91 | MP0003941_abnormal_skin_development | 0.87798018 |
92 | MP0004019_abnormal_vitamin_homeostasis | 0.87136985 |
93 | MP0002139_abnormal_hepatobiliary_system | 0.87068417 |
94 | MP0002277_abnormal_respiratory_mucosa | 0.86057644 |
95 | MP0003567_abnormal_fetal_cardiomyocyte | 0.84125904 |
96 | MP0000647_abnormal_sebaceous_gland | 0.82098356 |
97 | MP0002148_abnormal_hypersensitivity_rea | 0.82075232 |
98 | MP0005174_abnormal_tail_pigmentation | 0.80834840 |
99 | MP0002234_abnormal_pharynx_morphology | 0.80242434 |
100 | MP0002398_abnormal_bone_marrow | 0.80064489 |
101 | MP0005395_other_phenotype | 0.79384901 |
102 | MP0004142_abnormal_muscle_tone | 0.79199407 |
103 | MP0003121_genomic_imprinting | 0.78966932 |
104 | MP0000689_abnormal_spleen_morphology | 0.78248609 |
105 | MP0005397_hematopoietic_system_phenotyp | 0.77815521 |
106 | MP0001545_abnormal_hematopoietic_system | 0.77815521 |
107 | MP0000703_abnormal_thymus_morphology | 0.77750268 |
108 | MP0002085_abnormal_embryonic_tissue | 0.77477654 |
109 | MP0003984_embryonic_growth_retardation | 0.77300444 |
110 | MP0002736_abnormal_nociception_after | 0.76989594 |
111 | MP0006072_abnormal_retinal_apoptosis | 0.75874996 |
112 | MP0002722_abnormal_immune_system | 0.75827161 |
113 | MP0006276_abnormal_autonomic_nervous | 0.72923237 |
114 | MP0003656_abnormal_erythrocyte_physiolo | 0.72891018 |
115 | MP0001293_anophthalmia | 0.72657471 |
116 | MP0003943_abnormal_hepatobiliary_system | 0.72492542 |
117 | MP0002088_abnormal_embryonic_growth/wei | 0.71938488 |
118 | MP0002653_abnormal_ependyma_morphology | 0.71857796 |
119 | MP0002693_abnormal_pancreas_physiology | 0.71698649 |
120 | MP0004133_heterotaxia | 0.71214006 |
121 | MP0001881_abnormal_mammary_gland | 0.71090918 |
122 | MP0005391_vision/eye_phenotype | 0.70307966 |
123 | MP0001944_abnormal_pancreas_morphology | 0.70019223 |
124 | MP0002161_abnormal_fertility/fecundity | 0.69189149 |
125 | MP0005671_abnormal_response_to | 0.68791138 |
126 | MP0010307_abnormal_tumor_latency | 0.67918690 |
127 | MP0005220_abnormal_exocrine_pancreas | 0.66829426 |
128 | MP0002429_abnormal_blood_cell | 0.66818209 |
129 | MP0001542_abnormal_bone_strength | 0.66359658 |
130 | MP0005377_hearing/vestibular/ear_phenot | 0.64130828 |
131 | MP0003878_abnormal_ear_physiology | 0.64130828 |
132 | MP0005195_abnormal_posterior_eye | 0.63748197 |
133 | MP0003936_abnormal_reproductive_system | 0.63092733 |
134 | MP0000678_abnormal_parathyroid_gland | 0.62267931 |
135 | MP0005451_abnormal_body_composition | 0.59766070 |
136 | MP0003937_abnormal_limbs/digits/tail_de | 0.58952475 |
137 | MP0005266_abnormal_metabolism | 0.58709655 |
138 | MP0000716_abnormal_immune_system | 0.56059643 |
139 | MP0005384_cellular_phenotype | 0.55781372 |
140 | MP0002084_abnormal_developmental_patter | 0.55334764 |
141 | MP0003699_abnormal_female_reproductive | 0.55317364 |
142 | MP0005636_abnormal_mineral_homeostasis | 0.53977383 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.58111281 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 4.52957079 |
3 | Acute necrotizing encephalopathy (HP:0006965) | 4.18402194 |
4 | Mitochondrial inheritance (HP:0001427) | 4.01916170 |
5 | Hepatocellular necrosis (HP:0001404) | 3.99188830 |
6 | Birth length less than 3rd percentile (HP:0003561) | 3.95851265 |
7 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.88671113 |
8 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.88671113 |
9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.87805536 |
10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.84354845 |
11 | Reticulocytopenia (HP:0001896) | 3.80206080 |
12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.72990672 |
13 | Increased CSF lactate (HP:0002490) | 3.69275387 |
14 | Rough bone trabeculation (HP:0100670) | 3.69115746 |
15 | Cerebral hypomyelination (HP:0006808) | 3.61640736 |
16 | Hepatic necrosis (HP:0002605) | 3.55496215 |
17 | Aplastic anemia (HP:0001915) | 3.51817092 |
18 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.44530098 |
19 | Acute encephalopathy (HP:0006846) | 3.39117701 |
20 | Lipid accumulation in hepatocytes (HP:0006561) | 3.39021720 |
21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.36864690 |
22 | Oral leukoplakia (HP:0002745) | 3.34678988 |
23 | Macrocytic anemia (HP:0001972) | 3.27772805 |
24 | Carpal bone hypoplasia (HP:0001498) | 3.26921958 |
25 | Progressive macrocephaly (HP:0004481) | 3.25227323 |
26 | Increased serum lactate (HP:0002151) | 3.22939379 |
27 | Type I transferrin isoform profile (HP:0003642) | 3.17838264 |
28 | Increased intramyocellular lipid droplets (HP:0012240) | 3.17652790 |
29 | Molar tooth sign on MRI (HP:0002419) | 3.15525651 |
30 | Abnormality of midbrain morphology (HP:0002418) | 3.15525651 |
31 | Exertional dyspnea (HP:0002875) | 3.07882479 |
32 | Breast hypoplasia (HP:0003187) | 3.05371585 |
33 | Renal Fanconi syndrome (HP:0001994) | 3.03425939 |
34 | Abnormal trabecular bone morphology (HP:0100671) | 3.00192112 |
35 | Respiratory difficulties (HP:0002880) | 2.91958744 |
36 | Pallor (HP:0000980) | 2.90512640 |
37 | Hyperalaninemia (HP:0003348) | 2.81019912 |
38 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.81019912 |
39 | Abnormality of alanine metabolism (HP:0010916) | 2.81019912 |
40 | Type 2 muscle fiber atrophy (HP:0003554) | 2.76632509 |
41 | Abnormality of the preputium (HP:0100587) | 2.74984058 |
42 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.73534078 |
43 | 11 pairs of ribs (HP:0000878) | 2.73336413 |
44 | Nephronophthisis (HP:0000090) | 2.68475498 |
45 | Lactic acidosis (HP:0003128) | 2.68323652 |
46 | Premature graying of hair (HP:0002216) | 2.66867062 |
47 | Stomatitis (HP:0010280) | 2.66662793 |
48 | Exercise intolerance (HP:0003546) | 2.61669574 |
49 | Increased muscle lipid content (HP:0009058) | 2.59582584 |
50 | Irregular epiphyses (HP:0010582) | 2.56435613 |
51 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.53806979 |
52 | Muscle fiber atrophy (HP:0100295) | 2.51784637 |
53 | Chromsome breakage (HP:0040012) | 2.49531584 |
54 | Colon cancer (HP:0003003) | 2.48665795 |
55 | Pancytopenia (HP:0001876) | 2.44981228 |
56 | Congenital stationary night blindness (HP:0007642) | 2.42305209 |
57 | Bone marrow hypocellularity (HP:0005528) | 2.42304068 |
58 | Abnormal glycosylation (HP:0012345) | 2.40944672 |
59 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.40944672 |
60 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.40944672 |
61 | Abnormal protein glycosylation (HP:0012346) | 2.40944672 |
62 | CNS hypomyelination (HP:0003429) | 2.40938440 |
63 | Abnormality of glycolysis (HP:0004366) | 2.38254414 |
64 | Increased serum pyruvate (HP:0003542) | 2.38254414 |
65 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.36577910 |
66 | Microvesicular hepatic steatosis (HP:0001414) | 2.35966211 |
67 | Meckel diverticulum (HP:0002245) | 2.32602878 |
68 | Degeneration of anterior horn cells (HP:0002398) | 2.32408512 |
69 | Abnormality of the anterior horn cell (HP:0006802) | 2.32408512 |
70 | Secondary amenorrhea (HP:0000869) | 2.32153271 |
71 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.31460921 |
72 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.29665144 |
73 | Medial flaring of the eyebrow (HP:0010747) | 2.29472326 |
74 | Respiratory failure (HP:0002878) | 2.29261778 |
75 | Hypoplasia of the pons (HP:0012110) | 2.28686357 |
76 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.28503527 |
77 | Methylmalonic acidemia (HP:0002912) | 2.27728190 |
78 | Abnormality of the renal medulla (HP:0100957) | 2.27414452 |
79 | Abnormality of the renal cortex (HP:0011035) | 2.26964707 |
80 | Pancreatic fibrosis (HP:0100732) | 2.26489252 |
81 | Pancreatic cysts (HP:0001737) | 2.23947259 |
82 | Abnormality of the ileum (HP:0001549) | 2.23411980 |
83 | Abnormality of chromosome stability (HP:0003220) | 2.20076225 |
84 | Abnormality of the pons (HP:0007361) | 2.19845071 |
85 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.18247254 |
86 | Methylmalonic aciduria (HP:0012120) | 2.15195615 |
87 | Sclerocornea (HP:0000647) | 2.14444017 |
88 | Cerebral edema (HP:0002181) | 2.13027440 |
89 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.12993448 |
90 | Absent/shortened dynein arms (HP:0200106) | 2.12993448 |
91 | Optic disc pallor (HP:0000543) | 2.12913716 |
92 | Absent thumb (HP:0009777) | 2.12777864 |
93 | Occipital encephalocele (HP:0002085) | 2.10903231 |
94 | Myelodysplasia (HP:0002863) | 2.10812908 |
95 | Chronic hepatic failure (HP:0100626) | 2.10261992 |
96 | Chronic bronchitis (HP:0004469) | 2.07433523 |
97 | Leukodystrophy (HP:0002415) | 2.07014217 |
98 | Sparse eyelashes (HP:0000653) | 2.06856561 |
99 | Parakeratosis (HP:0001036) | 2.06772070 |
100 | True hermaphroditism (HP:0010459) | 2.05815408 |
101 | Median cleft lip (HP:0000161) | 2.05117803 |
102 | Patellar aplasia (HP:0006443) | 2.04593211 |
103 | Tubulointerstitial nephritis (HP:0001970) | 2.02132080 |
104 | Hypoplasia of the uterus (HP:0000013) | 2.01898724 |
105 | Abnormal ciliary motility (HP:0012262) | 2.01803076 |
106 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.00864068 |
107 | Abnormality of renal resorption (HP:0011038) | 2.00363453 |
108 | Cellular immunodeficiency (HP:0005374) | 1.99387989 |
109 | Reduced antithrombin III activity (HP:0001976) | 1.99189720 |
110 | Lethargy (HP:0001254) | 1.98722464 |
111 | Progressive microcephaly (HP:0000253) | 1.98565801 |
112 | CNS demyelination (HP:0007305) | 1.97705795 |
113 | Abnormality of urine glucose concentration (HP:0011016) | 1.97562882 |
114 | Glycosuria (HP:0003076) | 1.97562882 |
115 | Abnormality of placental membranes (HP:0011409) | 1.96480900 |
116 | Amniotic constriction ring (HP:0009775) | 1.96480900 |
117 | Abnormal spermatogenesis (HP:0008669) | 1.94349604 |
118 | Triphalangeal thumb (HP:0001199) | 1.93277805 |
119 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.92787296 |
120 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.92387397 |
121 | Microretrognathia (HP:0000308) | 1.92086611 |
122 | Premature ovarian failure (HP:0008209) | 1.90005689 |
123 | Nephrogenic diabetes insipidus (HP:0009806) | 1.89287454 |
124 | Renal cortical cysts (HP:0000803) | 1.89238244 |
125 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.89183822 |
126 | IgG deficiency (HP:0004315) | 1.88265531 |
127 | Supernumerary spleens (HP:0009799) | 1.88137192 |
128 | Abnormal drinking behavior (HP:0030082) | 1.87173500 |
129 | Polydipsia (HP:0001959) | 1.87173500 |
130 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.87078735 |
131 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.87078735 |
132 | Neutropenia (HP:0001875) | 1.86214539 |
133 | Congenital primary aphakia (HP:0007707) | 1.85069825 |
134 | Hyperglycinemia (HP:0002154) | 1.84971737 |
135 | Type II lissencephaly (HP:0007260) | 1.83928977 |
136 | Horseshoe kidney (HP:0000085) | 1.82109512 |
137 | Cleft eyelid (HP:0000625) | 1.81499350 |
138 | Duplicated collecting system (HP:0000081) | 1.80915873 |
139 | Rhinitis (HP:0012384) | 1.80581613 |
140 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.78041003 |
141 | Neoplasm of the adrenal cortex (HP:0100641) | 1.78018716 |
142 | Short tibia (HP:0005736) | 1.76979845 |
143 | Male pseudohermaphroditism (HP:0000037) | 1.76633062 |
144 | Facial cleft (HP:0002006) | 1.75636083 |
145 | Preaxial hand polydactyly (HP:0001177) | 1.75276533 |
146 | Congenital hepatic fibrosis (HP:0002612) | 1.73930583 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WEE1 | 4.41673314 |
2 | STK16 | 4.08119452 |
3 | BUB1 | 3.86895383 |
4 | EIF2AK1 | 3.73069914 |
5 | VRK2 | 3.59017464 |
6 | MAP4K2 | 3.38904366 |
7 | VRK1 | 2.80220403 |
8 | NME2 | 2.79456473 |
9 | FRK | 2.69531391 |
10 | EIF2AK3 | 2.63496742 |
11 | SRPK1 | 2.62226649 |
12 | CDC7 | 2.60945855 |
13 | TRIM28 | 2.37437278 |
14 | TESK2 | 2.30845901 |
15 | WNK3 | 2.26451486 |
16 | PNCK | 2.05119571 |
17 | TSSK6 | 2.00801437 |
18 | BRSK2 | 1.91981921 |
19 | PLK4 | 1.91586872 |
20 | ACVR1B | 1.82383196 |
21 | MKNK1 | 1.74145030 |
22 | NME1 | 1.72926239 |
23 | MST4 | 1.65785905 |
24 | EIF2AK2 | 1.64631268 |
25 | TAOK2 | 1.56184904 |
26 | PLK1 | 1.55142810 |
27 | DYRK3 | 1.52594894 |
28 | CDK19 | 1.50885366 |
29 | TTK | 1.43536174 |
30 | CCNB1 | 1.41111052 |
31 | PIM2 | 1.39800428 |
32 | PLK3 | 1.38444165 |
33 | MKNK2 | 1.34010207 |
34 | MAP3K3 | 1.28104684 |
35 | CDK7 | 1.27920174 |
36 | AURKB | 1.24252600 |
37 | WNK4 | 1.23876937 |
38 | PBK | 1.19445521 |
39 | INSRR | 1.19303307 |
40 | CDK8 | 1.14078703 |
41 | PASK | 1.13768119 |
42 | AURKA | 1.13527107 |
43 | ATR | 1.11883868 |
44 | NEK2 | 1.10484485 |
45 | MAP3K12 | 1.09205666 |
46 | ZAK | 1.05548989 |
47 | CHEK2 | 1.03594745 |
48 | NEK6 | 1.02233963 |
49 | PDK2 | 0.98619987 |
50 | PDK4 | 0.98481654 |
51 | PDK3 | 0.98481654 |
52 | TLK1 | 0.98057980 |
53 | TAOK3 | 0.95884360 |
54 | BRAF | 0.94827634 |
55 | MAP3K8 | 0.90065651 |
56 | BCKDK | 0.88921879 |
57 | MUSK | 0.86707918 |
58 | YES1 | 0.85530195 |
59 | BRSK1 | 0.85092092 |
60 | EPHA2 | 0.84797117 |
61 | RPS6KA4 | 0.81535189 |
62 | RPS6KA5 | 0.79372767 |
63 | RPS6KB2 | 0.79065869 |
64 | CSNK2A1 | 0.77302004 |
65 | BMPR1B | 0.75637209 |
66 | TEC | 0.74151970 |
67 | CSNK2A2 | 0.72200266 |
68 | DYRK2 | 0.71487916 |
69 | KDR | 0.70002990 |
70 | MAP3K11 | 0.69674088 |
71 | CSNK1G2 | 0.68829373 |
72 | LIMK1 | 0.67242546 |
73 | NEK1 | 0.67175961 |
74 | PINK1 | 0.66640844 |
75 | BCR | 0.65318163 |
76 | STK4 | 0.64859210 |
77 | CHEK1 | 0.63497830 |
78 | TESK1 | 0.62356847 |
79 | MAP4K1 | 0.62171197 |
80 | TGFBR1 | 0.61112914 |
81 | ABL2 | 0.60628516 |
82 | PRKCQ | 0.60169497 |
83 | MAP2K6 | 0.60105580 |
84 | STK24 | 0.59969194 |
85 | STK10 | 0.59714720 |
86 | CSNK1G3 | 0.59054805 |
87 | SIK3 | 0.58167643 |
88 | NUAK1 | 0.57707247 |
89 | ADRBK2 | 0.56973174 |
90 | CDK3 | 0.56248683 |
91 | ATM | 0.55616004 |
92 | MARK3 | 0.53689260 |
93 | NLK | 0.52899515 |
94 | OXSR1 | 0.52708892 |
95 | CSNK1A1L | 0.51726491 |
96 | GRK1 | 0.50295470 |
97 | PAK3 | 0.49112975 |
98 | DAPK1 | 0.48533453 |
99 | MAPK13 | 0.47546364 |
100 | TXK | 0.45125026 |
101 | AKT3 | 0.44231636 |
102 | MAPKAPK5 | 0.43852683 |
103 | CDK2 | 0.43611320 |
104 | IRAK4 | 0.41030173 |
105 | IKBKB | 0.40816631 |
106 | IRAK3 | 0.38599338 |
107 | CSNK1G1 | 0.37058589 |
108 | CSNK1E | 0.37023012 |
109 | CSNK1A1 | 0.36835362 |
110 | STK39 | 0.36619694 |
111 | BMPR2 | 0.36583930 |
112 | MAP2K7 | 0.36234891 |
113 | CDK1 | 0.35924038 |
114 | GRK7 | 0.35779303 |
115 | ADRBK1 | 0.35738853 |
116 | ERBB3 | 0.34363805 |
117 | CASK | 0.33753817 |
118 | CHUK | 0.33002948 |
119 | DAPK3 | 0.32979624 |
120 | PRKCE | 0.32908639 |
121 | MOS | 0.32902725 |
122 | PRKCI | 0.32702662 |
123 | ILK | 0.31279986 |
124 | PAK1 | 0.30439516 |
125 | STK38L | 0.29666576 |
126 | MAP2K2 | 0.29477002 |
127 | TNK2 | 0.29211089 |
128 | MYLK | 0.28881254 |
129 | ARAF | 0.27298690 |
130 | PIM1 | 0.26860880 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.51793478 |
2 | RNA polymerase_Homo sapiens_hsa03020 | 4.45668506 |
3 | Proteasome_Homo sapiens_hsa03050 | 4.19651650 |
4 | DNA replication_Homo sapiens_hsa03030 | 3.73778483 |
5 | * Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.55331107 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 3.28916924 |
7 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.87717591 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.76711523 |
9 | Spliceosome_Homo sapiens_hsa03040 | 2.75307732 |
10 | Protein export_Homo sapiens_hsa03060 | 2.69801639 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.65221092 |
12 | * RNA transport_Homo sapiens_hsa03013 | 2.47537534 |
13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.47019171 |
14 | Base excision repair_Homo sapiens_hsa03410 | 2.34622593 |
15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.33478114 |
16 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.24121805 |
17 | Parkinsons disease_Homo sapiens_hsa05012 | 2.06300964 |
18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.02286830 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.92943634 |
20 | Purine metabolism_Homo sapiens_hsa00230 | 1.81917158 |
21 | Cell cycle_Homo sapiens_hsa04110 | 1.81059601 |
22 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.78053174 |
23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.77201727 |
24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.53906112 |
25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.51168063 |
26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.43262238 |
27 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38689200 |
28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.38279953 |
29 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.29247066 |
30 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.21100589 |
31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18850334 |
32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.18540717 |
33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.16568245 |
34 | Peroxisome_Homo sapiens_hsa04146 | 1.14841256 |
35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.14335414 |
36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.13956294 |
37 | Phototransduction_Homo sapiens_hsa04744 | 1.12490773 |
38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.10557326 |
39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.02379852 |
40 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.02229310 |
41 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.99375753 |
42 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.96557820 |
43 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.90547839 |
44 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.89495263 |
45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.89234613 |
46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.88958416 |
47 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.86970847 |
48 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.81265406 |
49 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.77963963 |
50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76998615 |
51 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.76115027 |
52 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.72512606 |
53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.72272587 |
54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.71248256 |
55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.69817701 |
56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69636223 |
57 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.69484592 |
58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.68283071 |
59 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67996094 |
60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.60077448 |
61 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56547771 |
62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.56153822 |
63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55909689 |
64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.55171265 |
65 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.55094817 |
66 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.54182672 |
67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.53591655 |
68 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.50714873 |
69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.49803673 |
70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49717868 |
71 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.49394105 |
72 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.46818268 |
73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.44914008 |
74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41856873 |
75 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.41349388 |
76 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41158944 |
77 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39752626 |
78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.38680445 |
79 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.37115415 |
80 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.36768069 |
81 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.35487326 |
82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.35171622 |
83 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.34924399 |
84 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.34348901 |
85 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.34322547 |
86 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.32472311 |
87 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.32079551 |
88 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.30278208 |
89 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.29787171 |
90 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.29396003 |
91 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.28788715 |
92 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.28611535 |
93 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.28023249 |
94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.27962043 |
95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.26925619 |
96 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.26911004 |
97 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.25362485 |
98 | Galactose metabolism_Homo sapiens_hsa00052 | 0.23180437 |
99 | Legionellosis_Homo sapiens_hsa05134 | 0.22392054 |
100 | Carbon metabolism_Homo sapiens_hsa01200 | 0.21250240 |
101 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21062222 |
102 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.20853887 |
103 | Circadian rhythm_Homo sapiens_hsa04710 | 0.18718665 |
104 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.18601610 |
105 | HTLV-I infection_Homo sapiens_hsa05166 | 0.18417938 |
106 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.13225090 |
107 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.12780520 |
108 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.10814777 |
109 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10674139 |
110 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.10463729 |
111 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.10071408 |
112 | Alcoholism_Homo sapiens_hsa05034 | 0.08089835 |
113 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.06869947 |
114 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.06624395 |
115 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.05349243 |
116 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.05226970 |
117 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.05135803 |
118 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.04739543 |
119 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.04363229 |
120 | Other glycan degradation_Homo sapiens_hsa00511 | 0.04302359 |
121 | Measles_Homo sapiens_hsa05162 | 0.03704844 |
122 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.03655944 |
123 | Allograft rejection_Homo sapiens_hsa05330 | 0.03324190 |
124 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.02832572 |
125 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.02524831 |
126 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.02358513 |