RPP38

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.90907661
2maturation of SSU-rRNA (GO:0030490)5.31498137
3DNA deamination (GO:0045006)5.03819191
4mitochondrial respiratory chain complex assembly (GO:0033108)4.75683214
5proteasome assembly (GO:0043248)4.66811181
6ribosomal small subunit biogenesis (GO:0042274)4.63692514
7ribosomal large subunit biogenesis (GO:0042273)4.58347050
8respiratory chain complex IV assembly (GO:0008535)4.56242561
9rRNA modification (GO:0000154)4.46512513
10termination of RNA polymerase III transcription (GO:0006386)4.38583373
11transcription elongation from RNA polymerase III promoter (GO:0006385)4.38583373
12viral transcription (GO:0019083)4.36379640
13cytochrome complex assembly (GO:0017004)4.34647866
14translational termination (GO:0006415)4.31323078
15ribonucleoprotein complex biogenesis (GO:0022613)4.21490953
16purine nucleobase biosynthetic process (GO:0009113)4.19862011
177-methylguanosine mRNA capping (GO:0006370)4.14189235
18termination of RNA polymerase I transcription (GO:0006363)4.13922346
19L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.13646797
20SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.10232189
21deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.09959581
22transcription elongation from RNA polymerase I promoter (GO:0006362)4.09591854
237-methylguanosine RNA capping (GO:0009452)4.06681594
24RNA capping (GO:0036260)4.06681594
25cotranslational protein targeting to membrane (GO:0006613)4.05844318
26nucleobase biosynthetic process (GO:0046112)4.03688858
27protein targeting to ER (GO:0045047)4.00714656
28ribosome biogenesis (GO:0042254)3.97620923
29rRNA processing (GO:0006364)3.97314005
30formation of translation preinitiation complex (GO:0001731)3.93695000
31translational elongation (GO:0006414)3.88497273
32transcription from RNA polymerase I promoter (GO:0006360)3.88249009
33protein localization to endoplasmic reticulum (GO:0070972)3.87859883
34pseudouridine synthesis (GO:0001522)3.86393776
35mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.85473642
36rRNA metabolic process (GO:0016072)3.83245947
37establishment of protein localization to endoplasmic reticulum (GO:0072599)3.80766646
38translational initiation (GO:0006413)3.78663536
39rRNA methylation (GO:0031167)3.77878583
40ribosome assembly (GO:0042255)3.77767157
41cellular component biogenesis (GO:0044085)3.72438905
42DNA strand elongation (GO:0022616)3.72258092
43protein-cofactor linkage (GO:0018065)3.72138336
44translation (GO:0006412)3.71665911
45telomere maintenance via semi-conservative replication (GO:0032201)3.71278283
46negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.69828829
47DNA strand elongation involved in DNA replication (GO:0006271)3.69646248
48peptidyl-histidine modification (GO:0018202)3.63756752
49tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.61326932
50RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.61326932
51L-methionine biosynthetic process (GO:0071265)3.58833007
52amino acid salvage (GO:0043102)3.58833007
53L-methionine salvage (GO:0071267)3.58833007
54establishment of integrated proviral latency (GO:0075713)3.58475369
55transcription initiation from RNA polymerase I promoter (GO:0006361)3.58324818
56positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.57018826
57regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.55758115
58CENP-A containing nucleosome assembly (GO:0034080)3.55653823
59ubiquinone biosynthetic process (GO:0006744)3.55259405
60establishment of protein localization to mitochondrial membrane (GO:0090151)3.54227294
61transcription-coupled nucleotide-excision repair (GO:0006283)3.54093029
62anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.51776748
63chromatin remodeling at centromere (GO:0031055)3.49934827
64maturation of 5.8S rRNA (GO:0000460)3.49071372
65* tRNA processing (GO:0008033)3.45997048
66water-soluble vitamin biosynthetic process (GO:0042364)3.44465131
67mitotic metaphase plate congression (GO:0007080)3.43655010
68cellular protein complex disassembly (GO:0043624)3.41635619
69nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.41087907
70negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.40698100
71negative regulation of ligase activity (GO:0051352)3.40698100
72DNA replication initiation (GO:0006270)3.40351032
73electron transport chain (GO:0022900)3.40189141
74mannosylation (GO:0097502)3.40169633
75respiratory electron transport chain (GO:0022904)3.40008666
76viral life cycle (GO:0019058)3.39473128
77telomere maintenance via recombination (GO:0000722)3.38421472
78exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.35692236
79spliceosomal snRNP assembly (GO:0000387)3.35086761
80mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.34633542
81regulation of mitotic spindle checkpoint (GO:1903504)3.34503198
82regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.34503198
83DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.33873490
84regulation of cellular amino acid metabolic process (GO:0006521)3.32441680
85IMP biosynthetic process (GO:0006188)3.30893889
86nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.30804268
87intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.28556989
88signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.28556989
89signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.28383210
90signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.28383210
91signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.28383210
92regulation of mitochondrial translation (GO:0070129)3.27359559
93protein neddylation (GO:0045116)3.25308350
94mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.24887170
95mitochondrial respiratory chain complex I assembly (GO:0032981)3.24887170
96NADH dehydrogenase complex assembly (GO:0010257)3.24887170
97telomere maintenance via telomere lengthening (GO:0010833)3.21957996
98DNA replication checkpoint (GO:0000076)3.20199080
99signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20186396
100signal transduction involved in DNA damage checkpoint (GO:0072422)3.20186396
101ubiquinone metabolic process (GO:0006743)3.20166951
102transcription elongation from RNA polymerase II promoter (GO:0006368)3.20127868
103protein complex biogenesis (GO:0070271)3.19319162
104chaperone-mediated protein transport (GO:0072321)3.17425187
105DNA-templated transcription, elongation (GO:0006354)3.15844792
106protein targeting to mitochondrion (GO:0006626)3.15604005
107signal transduction involved in cell cycle checkpoint (GO:0072395)3.14933817
108ATP synthesis coupled proton transport (GO:0015986)3.14764433
109energy coupled proton transport, down electrochemical gradient (GO:0015985)3.14764433
110tRNA modification (GO:0006400)3.14272786
111positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.13527248
112protein K6-linked ubiquitination (GO:0085020)3.12516527
113GTP biosynthetic process (GO:0006183)3.12317782
114* ncRNA processing (GO:0034470)3.10385424
115establishment of protein localization to mitochondrion (GO:0072655)3.10048392
116iron-sulfur cluster assembly (GO:0016226)3.10022522
117metallo-sulfur cluster assembly (GO:0031163)3.10022522
118cullin deneddylation (GO:0010388)3.08277806
119protein deneddylation (GO:0000338)3.08061081
120positive regulation of ligase activity (GO:0051351)3.06180020
121preassembly of GPI anchor in ER membrane (GO:0016254)3.00243476
122male meiosis I (GO:0007141)2.98878505
123* tRNA metabolic process (GO:0006399)2.97403503
124pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.96988137
125somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.95359326
126isotype switching (GO:0045190)2.95359326
127somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.95359326
128epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.87694190
129protein localization to mitochondrion (GO:0070585)2.86644870
130* ncRNA metabolic process (GO:0034660)2.86217612
131transcription from mitochondrial promoter (GO:0006390)2.85862494
132DNA catabolic process, exonucleolytic (GO:0000738)2.85683903
133base-excision repair, AP site formation (GO:0006285)2.77946173
134tRNA methylation (GO:0030488)2.77843082
135deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.73293369
136DNA double-strand break processing (GO:0000729)2.72645882
137somatic hypermutation of immunoglobulin genes (GO:0016446)2.72424699
138somatic diversification of immune receptors via somatic mutation (GO:0002566)2.72424699
139UTP biosynthetic process (GO:0006228)2.69036908
140quinone biosynthetic process (GO:1901663)2.68866376
141pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.68784212
142RNA modification (GO:0009451)2.65384006
143recombinational repair (GO:0000725)2.63437856
144double-strand break repair via homologous recombination (GO:0000724)2.62726146

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.31951877
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.65139660
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.37905112
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.21330182
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.00233411
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.97076580
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.60025788
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.30565503
9CREB1_15753290_ChIP-ChIP_HEK293T_Human3.21330717
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.12505401
11* HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.04697127
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.02496361
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.99514176
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.96402593
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.93303239
16E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.89580252
17* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.89326509
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.84897392
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.79676609
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.79142965
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.76653752
22VDR_23849224_ChIP-Seq_CD4+_Human2.76225541
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.66569697
24FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49548663
25DCP1A_22483619_ChIP-Seq_HELA_Human2.44889237
26ZNF274_21170338_ChIP-Seq_K562_Hela2.40117885
27FOXP3_21729870_ChIP-Seq_TREG_Human2.39390967
28XRN2_22483619_ChIP-Seq_HELA_Human2.36862487
29FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.34753094
30SRF_21415370_ChIP-Seq_HL-1_Mouse2.27752000
31* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.24892636
32THAP11_20581084_ChIP-Seq_MESCs_Mouse2.24078991
33NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22002187
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.12882615
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.11412358
36GABP_19822575_ChIP-Seq_HepG2_Human2.10124541
37ELK1_19687146_ChIP-ChIP_HELA_Human2.06429087
38PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.96314833
39* TTF2_22483619_ChIP-Seq_HELA_Human1.94691957
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.90640673
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.90384377
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87927761
43NOTCH1_21737748_ChIP-Seq_TLL_Human1.86025311
44* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.78557294
45* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.76949459
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.74883257
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.74691207
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.74016007
49AR_21909140_ChIP-Seq_LNCAP_Human1.69580972
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.67805784
51FOXM1_23109430_ChIP-Seq_U2OS_Human1.58842925
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.58835182
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57177313
54ERG_20887958_ChIP-Seq_HPC-7_Mouse1.50533107
55NANOG_18555785_ChIP-Seq_MESCs_Mouse1.43914168
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.43093171
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38481812
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37810945
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.37539922
60VDR_22108803_ChIP-Seq_LS180_Human1.36913012
61* TP53_22573176_ChIP-Seq_HFKS_Human1.36487102
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.35345781
63EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33063506
64E2F1_21310950_ChIP-Seq_MCF-7_Human1.31137077
65CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27677437
66ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.26064528
67KDM5A_27292631_Chip-Seq_BREAST_Human1.24048928
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.22892546
69CIITA_25753668_ChIP-Seq_RAJI_Human1.19629816
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.18621825
71MYC_18940864_ChIP-ChIP_HL60_Human1.13040414
72KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.09235906
73EWS_26573619_Chip-Seq_HEK293_Human1.07039877
74CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04354387
75CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.03501518
76DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.01354714
77* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00828172
78GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97471627
79SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95876897
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94969716
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92314831
82FOXA1_27270436_Chip-Seq_PROSTATE_Human0.91322686
83FOXA1_25329375_ChIP-Seq_VCAP_Human0.91322686
84IGF1R_20145208_ChIP-Seq_DFB_Human0.90724478
85AR_20517297_ChIP-Seq_VCAP_Human0.90591738
86* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89889048
87KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88772402
88ELF5_23300383_ChIP-Seq_T47D_Human0.88688624
89FLI1_27457419_Chip-Seq_LIVER_Mouse0.87881723
90RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87518015
91IRF1_19129219_ChIP-ChIP_H3396_Human0.86438388
92* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.86397847
93SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85855338
94SOX17_20123909_ChIP-Seq_XEN_Mouse0.85303058
95* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.82967289
96PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.82898358
97STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82457140
98GATA3_21878914_ChIP-Seq_MCF-7_Human0.82379307
99* ERA_21632823_ChIP-Seq_H3396_Human0.82319008
100* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.81999879
101SPI1_23547873_ChIP-Seq_NB4_Human0.81855264
102TFEB_21752829_ChIP-Seq_HELA_Human0.81665645
103CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81219948
104FOXP1_21924763_ChIP-Seq_HESCs_Human0.80815560
105EGR1_23403033_ChIP-Seq_LIVER_Mouse0.80503225
106HOXB7_26014856_ChIP-Seq_BT474_Human0.80202398
107NANOG_20526341_ChIP-Seq_ESCs_Human0.79759947
108GATA3_26560356_Chip-Seq_TH2_Human0.79289667
109NCOR_22424771_ChIP-Seq_293T_Human0.79019914
110KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77361500
111MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.76584535
112DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.76368857
113CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.75030111
114TBX5_21415370_ChIP-Seq_HL-1_Mouse0.73826414
115ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.71989851
116IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.70331121
117CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.69615738
118CTCF_18555785_ChIP-Seq_MESCs_Mouse0.69035587
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.68265418
120TP63_19390658_ChIP-ChIP_HaCaT_Human0.67708057
121NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.66717593
122TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.65300099
123SOX2_18555785_ChIP-Seq_MESCs_Mouse0.65139674
124HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.63907373
125HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.63601718

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.65803470
2MP0008057_abnormal_DNA_replication4.37093633
3MP0010094_abnormal_chromosome_stability4.32716443
4MP0004957_abnormal_blastocyst_morpholog4.25329589
5MP0008058_abnormal_DNA_repair4.21333288
6MP0003111_abnormal_nucleus_morphology3.83477642
7MP0003077_abnormal_cell_cycle3.52958058
8MP0003718_maternal_effect2.82881208
9MP0008877_abnormal_DNA_methylation2.72693250
10MP0003123_paternal_imprinting2.69206325
11MP0002396_abnormal_hematopoietic_system2.60902279
12MP0008932_abnormal_embryonic_tissue2.60868278
13MP0008007_abnormal_cellular_replicative2.60330801
14MP0003806_abnormal_nucleotide_metabolis2.56894153
15MP0009379_abnormal_foot_pigmentation2.46975838
16MP0003786_premature_aging2.16112166
17MP0003195_calcinosis2.15170064
18MP0008875_abnormal_xenobiotic_pharmacok2.11476854
19MP0003315_abnormal_perineum_morphology1.99568318
20MP0003186_abnormal_redox_activity1.97531978
21MP0006292_abnormal_olfactory_placode1.84889461
22MP0005645_abnormal_hypothalamus_physiol1.75835164
23MP0008789_abnormal_olfactory_epithelium1.73986110
24MP0002210_abnormal_sex_determination1.73133638
25MP0001929_abnormal_gametogenesis1.66409442
26MP0005084_abnormal_gallbladder_morpholo1.66382917
27MP0001730_embryonic_growth_arrest1.65611102
28MP0006036_abnormal_mitochondrial_physio1.63730232
29MP0003787_abnormal_imprinting1.58735015
30MP0009333_abnormal_splenocyte_physiolog1.51514986
31MP0002837_dystrophic_cardiac_calcinosis1.51279094
32MP0001145_abnormal_male_reproductive1.49713891
33MP0002095_abnormal_skin_pigmentation1.47108028
34MP0000350_abnormal_cell_proliferation1.46552897
35MP0002876_abnormal_thyroid_physiology1.44886008
36MP0000015_abnormal_ear_pigmentation1.44833342
37MP0005551_abnormal_eye_electrophysiolog1.40681172
38MP0000653_abnormal_sex_gland1.40170592
39MP0008872_abnormal_physiological_respon1.39949698
40MP0001984_abnormal_olfaction1.36103053
41MP0005253_abnormal_eye_physiology1.35757639
42MP0006035_abnormal_mitochondrial_morpho1.35068972
43MP0001529_abnormal_vocalization1.34961155
44MP0005075_abnormal_melanosome_morpholog1.34433042
45MP0002254_reproductive_system_inflammat1.32218067
46MP0000313_abnormal_cell_death1.31263041
47MP0004147_increased_porphyrin_level1.28711123
48MP0002938_white_spotting1.26826837
49MP0005646_abnormal_pituitary_gland1.25693595
50MP0002132_abnormal_respiratory_system1.25043659
51MP0003763_abnormal_thymus_physiology1.21870940
52MP0001986_abnormal_taste_sensitivity1.18364946
53MP0009697_abnormal_copulation1.16561680
54MP0001905_abnormal_dopamine_level1.15554075
55MP0000490_abnormal_crypts_of1.15347714
56MP0005389_reproductive_system_phenotype1.14577751
57MP0001697_abnormal_embryo_size1.13999633
58MP0004808_abnormal_hematopoietic_stem1.13221415
59MP0001188_hyperpigmentation1.12662724
60MP0003011_delayed_dark_adaptation1.10221436
61MP0000427_abnormal_hair_cycle1.10092001
62MP0000465_gastrointestinal_hemorrhage1.08422447
63MP0000358_abnormal_cell_content/1.08047207
64MP0005409_darkened_coat_color1.06994429
65MP0000631_abnormal_neuroendocrine_gland1.06208202
66MP0002163_abnormal_gland_morphology1.05380681
67MP0004043_abnormal_pH_regulation1.05071316
68MP0002019_abnormal_tumor_incidence1.04705503
69MP0003136_yellow_coat_color1.03868295
70MP0002102_abnormal_ear_morphology1.03294928
71MP0003698_abnormal_male_reproductive1.02091220
72MP0001919_abnormal_reproductive_system1.01479924
73MP0005410_abnormal_fertilization1.00551568
74MP0002080_prenatal_lethality0.98152313
75MP0001764_abnormal_homeostasis0.97625214
76MP0008995_early_reproductive_senescence0.97617187
77MP0005394_taste/olfaction_phenotype0.96846638
78MP0005499_abnormal_olfactory_system0.96846638
79MP0001119_abnormal_female_reproductive0.96212945
80MP0003646_muscle_fatigue0.96193648
81MP0005379_endocrine/exocrine_gland_phen0.96096561
82MP0001672_abnormal_embryogenesis/_devel0.93583238
83MP0005380_embryogenesis_phenotype0.93583238
84MP0005408_hypopigmentation0.93141393
85MP0009046_muscle_twitch0.90332777
86MP0000372_irregular_coat_pigmentation0.89182239
87MP0005332_abnormal_amino_acid0.89086888
88MP0002160_abnormal_reproductive_system0.88881337
89MP0001485_abnormal_pinna_reflex0.88678716
90MP0008260_abnormal_autophagy0.88605274
91MP0003941_abnormal_skin_development0.87798018
92MP0004019_abnormal_vitamin_homeostasis0.87136985
93MP0002139_abnormal_hepatobiliary_system0.87068417
94MP0002277_abnormal_respiratory_mucosa0.86057644
95MP0003567_abnormal_fetal_cardiomyocyte0.84125904
96MP0000647_abnormal_sebaceous_gland0.82098356
97MP0002148_abnormal_hypersensitivity_rea0.82075232
98MP0005174_abnormal_tail_pigmentation0.80834840
99MP0002234_abnormal_pharynx_morphology0.80242434
100MP0002398_abnormal_bone_marrow0.80064489
101MP0005395_other_phenotype0.79384901
102MP0004142_abnormal_muscle_tone0.79199407
103MP0003121_genomic_imprinting0.78966932
104MP0000689_abnormal_spleen_morphology0.78248609
105MP0005397_hematopoietic_system_phenotyp0.77815521
106MP0001545_abnormal_hematopoietic_system0.77815521
107MP0000703_abnormal_thymus_morphology0.77750268
108MP0002085_abnormal_embryonic_tissue0.77477654
109MP0003984_embryonic_growth_retardation0.77300444
110MP0002736_abnormal_nociception_after0.76989594
111MP0006072_abnormal_retinal_apoptosis0.75874996
112MP0002722_abnormal_immune_system0.75827161
113MP0006276_abnormal_autonomic_nervous0.72923237
114MP0003656_abnormal_erythrocyte_physiolo0.72891018
115MP0001293_anophthalmia0.72657471
116MP0003943_abnormal_hepatobiliary_system0.72492542
117MP0002088_abnormal_embryonic_growth/wei0.71938488
118MP0002653_abnormal_ependyma_morphology0.71857796
119MP0002693_abnormal_pancreas_physiology0.71698649
120MP0004133_heterotaxia0.71214006
121MP0001881_abnormal_mammary_gland0.71090918
122MP0005391_vision/eye_phenotype0.70307966
123MP0001944_abnormal_pancreas_morphology0.70019223
124MP0002161_abnormal_fertility/fecundity0.69189149
125MP0005671_abnormal_response_to0.68791138
126MP0010307_abnormal_tumor_latency0.67918690
127MP0005220_abnormal_exocrine_pancreas0.66829426
128MP0002429_abnormal_blood_cell0.66818209
129MP0001542_abnormal_bone_strength0.66359658
130MP0005377_hearing/vestibular/ear_phenot0.64130828
131MP0003878_abnormal_ear_physiology0.64130828
132MP0005195_abnormal_posterior_eye0.63748197
133MP0003936_abnormal_reproductive_system0.63092733
134MP0000678_abnormal_parathyroid_gland0.62267931
135MP0005451_abnormal_body_composition0.59766070
136MP0003937_abnormal_limbs/digits/tail_de0.58952475
137MP0005266_abnormal_metabolism0.58709655
138MP0000716_abnormal_immune_system0.56059643
139MP0005384_cellular_phenotype0.55781372
140MP0002084_abnormal_developmental_patter0.55334764
141MP0003699_abnormal_female_reproductive0.55317364
142MP0005636_abnormal_mineral_homeostasis0.53977383

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.58111281
2Abnormal number of erythroid precursors (HP:0012131)4.52957079
3Acute necrotizing encephalopathy (HP:0006965)4.18402194
4Mitochondrial inheritance (HP:0001427)4.01916170
5Hepatocellular necrosis (HP:0001404)3.99188830
6Birth length less than 3rd percentile (HP:0003561)3.95851265
7Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.88671113
8Decreased activity of mitochondrial respiratory chain (HP:0008972)3.88671113
9Abnormal mitochondria in muscle tissue (HP:0008316)3.87805536
10Increased hepatocellular lipid droplets (HP:0006565)3.84354845
11Reticulocytopenia (HP:0001896)3.80206080
123-Methylglutaconic aciduria (HP:0003535)3.72990672
13Increased CSF lactate (HP:0002490)3.69275387
14Rough bone trabeculation (HP:0100670)3.69115746
15Cerebral hypomyelination (HP:0006808)3.61640736
16Hepatic necrosis (HP:0002605)3.55496215
17Aplastic anemia (HP:0001915)3.51817092
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.44530098
19Acute encephalopathy (HP:0006846)3.39117701
20Lipid accumulation in hepatocytes (HP:0006561)3.39021720
21Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.36864690
22Oral leukoplakia (HP:0002745)3.34678988
23Macrocytic anemia (HP:0001972)3.27772805
24Carpal bone hypoplasia (HP:0001498)3.26921958
25Progressive macrocephaly (HP:0004481)3.25227323
26Increased serum lactate (HP:0002151)3.22939379
27Type I transferrin isoform profile (HP:0003642)3.17838264
28Increased intramyocellular lipid droplets (HP:0012240)3.17652790
29Molar tooth sign on MRI (HP:0002419)3.15525651
30Abnormality of midbrain morphology (HP:0002418)3.15525651
31Exertional dyspnea (HP:0002875)3.07882479
32Breast hypoplasia (HP:0003187)3.05371585
33Renal Fanconi syndrome (HP:0001994)3.03425939
34Abnormal trabecular bone morphology (HP:0100671)3.00192112
35Respiratory difficulties (HP:0002880)2.91958744
36Pallor (HP:0000980)2.90512640
37Hyperalaninemia (HP:0003348)2.81019912
38Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.81019912
39Abnormality of alanine metabolism (HP:0010916)2.81019912
40Type 2 muscle fiber atrophy (HP:0003554)2.76632509
41Abnormality of the preputium (HP:0100587)2.74984058
42Aplasia/Hypoplasia of the sacrum (HP:0008517)2.73534078
4311 pairs of ribs (HP:0000878)2.73336413
44Nephronophthisis (HP:0000090)2.68475498
45Lactic acidosis (HP:0003128)2.68323652
46Premature graying of hair (HP:0002216)2.66867062
47Stomatitis (HP:0010280)2.66662793
48Exercise intolerance (HP:0003546)2.61669574
49Increased muscle lipid content (HP:0009058)2.59582584
50Irregular epiphyses (HP:0010582)2.56435613
51Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.53806979
52Muscle fiber atrophy (HP:0100295)2.51784637
53Chromsome breakage (HP:0040012)2.49531584
54Colon cancer (HP:0003003)2.48665795
55Pancytopenia (HP:0001876)2.44981228
56Congenital stationary night blindness (HP:0007642)2.42305209
57Bone marrow hypocellularity (HP:0005528)2.42304068
58Abnormal glycosylation (HP:0012345)2.40944672
59Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.40944672
60Abnormal protein N-linked glycosylation (HP:0012347)2.40944672
61Abnormal protein glycosylation (HP:0012346)2.40944672
62CNS hypomyelination (HP:0003429)2.40938440
63Abnormality of glycolysis (HP:0004366)2.38254414
64Increased serum pyruvate (HP:0003542)2.38254414
65Aplasia/hypoplasia of the uterus (HP:0008684)2.36577910
66Microvesicular hepatic steatosis (HP:0001414)2.35966211
67Meckel diverticulum (HP:0002245)2.32602878
68Degeneration of anterior horn cells (HP:0002398)2.32408512
69Abnormality of the anterior horn cell (HP:0006802)2.32408512
70Secondary amenorrhea (HP:0000869)2.32153271
71Chromosomal breakage induced by crosslinking agents (HP:0003221)2.31460921
72Abnormality of the heme biosynthetic pathway (HP:0010472)2.29665144
73Medial flaring of the eyebrow (HP:0010747)2.29472326
74Respiratory failure (HP:0002878)2.29261778
75Hypoplasia of the pons (HP:0012110)2.28686357
76Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.28503527
77Methylmalonic acidemia (HP:0002912)2.27728190
78Abnormality of the renal medulla (HP:0100957)2.27414452
79Abnormality of the renal cortex (HP:0011035)2.26964707
80Pancreatic fibrosis (HP:0100732)2.26489252
81Pancreatic cysts (HP:0001737)2.23947259
82Abnormality of the ileum (HP:0001549)2.23411980
83Abnormality of chromosome stability (HP:0003220)2.20076225
84Abnormality of the pons (HP:0007361)2.19845071
85Abnormal respiratory motile cilium physiology (HP:0012261)2.18247254
86Methylmalonic aciduria (HP:0012120)2.15195615
87Sclerocornea (HP:0000647)2.14444017
88Cerebral edema (HP:0002181)2.13027440
89Dynein arm defect of respiratory motile cilia (HP:0012255)2.12993448
90Absent/shortened dynein arms (HP:0200106)2.12993448
91Optic disc pallor (HP:0000543)2.12913716
92Absent thumb (HP:0009777)2.12777864
93Occipital encephalocele (HP:0002085)2.10903231
94Myelodysplasia (HP:0002863)2.10812908
95Chronic hepatic failure (HP:0100626)2.10261992
96Chronic bronchitis (HP:0004469)2.07433523
97Leukodystrophy (HP:0002415)2.07014217
98Sparse eyelashes (HP:0000653)2.06856561
99Parakeratosis (HP:0001036)2.06772070
100True hermaphroditism (HP:0010459)2.05815408
101Median cleft lip (HP:0000161)2.05117803
102Patellar aplasia (HP:0006443)2.04593211
103Tubulointerstitial nephritis (HP:0001970)2.02132080
104Hypoplasia of the uterus (HP:0000013)2.01898724
105Abnormal ciliary motility (HP:0012262)2.01803076
106Aplasia/Hypoplasia of the uvula (HP:0010293)2.00864068
107Abnormality of renal resorption (HP:0011038)2.00363453
108Cellular immunodeficiency (HP:0005374)1.99387989
109Reduced antithrombin III activity (HP:0001976)1.99189720
110Lethargy (HP:0001254)1.98722464
111Progressive microcephaly (HP:0000253)1.98565801
112CNS demyelination (HP:0007305)1.97705795
113Abnormality of urine glucose concentration (HP:0011016)1.97562882
114Glycosuria (HP:0003076)1.97562882
115Abnormality of placental membranes (HP:0011409)1.96480900
116Amniotic constriction ring (HP:0009775)1.96480900
117Abnormal spermatogenesis (HP:0008669)1.94349604
118Triphalangeal thumb (HP:0001199)1.93277805
119Aplasia/Hypoplasia of the tongue (HP:0010295)1.92787296
120Aplasia/Hypoplasia of the patella (HP:0006498)1.92387397
121Microretrognathia (HP:0000308)1.92086611
122Premature ovarian failure (HP:0008209)1.90005689
123Nephrogenic diabetes insipidus (HP:0009806)1.89287454
124Renal cortical cysts (HP:0000803)1.89238244
125Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.89183822
126IgG deficiency (HP:0004315)1.88265531
127Supernumerary spleens (HP:0009799)1.88137192
128Abnormal drinking behavior (HP:0030082)1.87173500
129Polydipsia (HP:0001959)1.87173500
130Abnormal respiratory epithelium morphology (HP:0012253)1.87078735
131Abnormal respiratory motile cilium morphology (HP:0005938)1.87078735
132Neutropenia (HP:0001875)1.86214539
133Congenital primary aphakia (HP:0007707)1.85069825
134Hyperglycinemia (HP:0002154)1.84971737
135Type II lissencephaly (HP:0007260)1.83928977
136Horseshoe kidney (HP:0000085)1.82109512
137Cleft eyelid (HP:0000625)1.81499350
138Duplicated collecting system (HP:0000081)1.80915873
139Rhinitis (HP:0012384)1.80581613
140Hypoplasia of the capital femoral epiphysis (HP:0003090)1.78041003
141Neoplasm of the adrenal cortex (HP:0100641)1.78018716
142Short tibia (HP:0005736)1.76979845
143Male pseudohermaphroditism (HP:0000037)1.76633062
144Facial cleft (HP:0002006)1.75636083
145Preaxial hand polydactyly (HP:0001177)1.75276533
146Congenital hepatic fibrosis (HP:0002612)1.73930583

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.41673314
2STK164.08119452
3BUB13.86895383
4EIF2AK13.73069914
5VRK23.59017464
6MAP4K23.38904366
7VRK12.80220403
8NME22.79456473
9FRK2.69531391
10EIF2AK32.63496742
11SRPK12.62226649
12CDC72.60945855
13TRIM282.37437278
14TESK22.30845901
15WNK32.26451486
16PNCK2.05119571
17TSSK62.00801437
18BRSK21.91981921
19PLK41.91586872
20ACVR1B1.82383196
21MKNK11.74145030
22NME11.72926239
23MST41.65785905
24EIF2AK21.64631268
25TAOK21.56184904
26PLK11.55142810
27DYRK31.52594894
28CDK191.50885366
29TTK1.43536174
30CCNB11.41111052
31PIM21.39800428
32PLK31.38444165
33MKNK21.34010207
34MAP3K31.28104684
35CDK71.27920174
36AURKB1.24252600
37WNK41.23876937
38PBK1.19445521
39INSRR1.19303307
40CDK81.14078703
41PASK1.13768119
42AURKA1.13527107
43ATR1.11883868
44NEK21.10484485
45MAP3K121.09205666
46ZAK1.05548989
47CHEK21.03594745
48NEK61.02233963
49PDK20.98619987
50PDK40.98481654
51PDK30.98481654
52TLK10.98057980
53TAOK30.95884360
54BRAF0.94827634
55MAP3K80.90065651
56BCKDK0.88921879
57MUSK0.86707918
58YES10.85530195
59BRSK10.85092092
60EPHA20.84797117
61RPS6KA40.81535189
62RPS6KA50.79372767
63RPS6KB20.79065869
64CSNK2A10.77302004
65BMPR1B0.75637209
66TEC0.74151970
67CSNK2A20.72200266
68DYRK20.71487916
69KDR0.70002990
70MAP3K110.69674088
71CSNK1G20.68829373
72LIMK10.67242546
73NEK10.67175961
74PINK10.66640844
75BCR0.65318163
76STK40.64859210
77CHEK10.63497830
78TESK10.62356847
79MAP4K10.62171197
80TGFBR10.61112914
81ABL20.60628516
82PRKCQ0.60169497
83MAP2K60.60105580
84STK240.59969194
85STK100.59714720
86CSNK1G30.59054805
87SIK30.58167643
88NUAK10.57707247
89ADRBK20.56973174
90CDK30.56248683
91ATM0.55616004
92MARK30.53689260
93NLK0.52899515
94OXSR10.52708892
95CSNK1A1L0.51726491
96GRK10.50295470
97PAK30.49112975
98DAPK10.48533453
99MAPK130.47546364
100TXK0.45125026
101AKT30.44231636
102MAPKAPK50.43852683
103CDK20.43611320
104IRAK40.41030173
105IKBKB0.40816631
106IRAK30.38599338
107CSNK1G10.37058589
108CSNK1E0.37023012
109CSNK1A10.36835362
110STK390.36619694
111BMPR20.36583930
112MAP2K70.36234891
113CDK10.35924038
114GRK70.35779303
115ADRBK10.35738853
116ERBB30.34363805
117CASK0.33753817
118CHUK0.33002948
119DAPK30.32979624
120PRKCE0.32908639
121MOS0.32902725
122PRKCI0.32702662
123ILK0.31279986
124PAK10.30439516
125STK38L0.29666576
126MAP2K20.29477002
127TNK20.29211089
128MYLK0.28881254
129ARAF0.27298690
130PIM10.26860880

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.51793478
2RNA polymerase_Homo sapiens_hsa030204.45668506
3Proteasome_Homo sapiens_hsa030504.19651650
4DNA replication_Homo sapiens_hsa030303.73778483
5* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.55331107
6Mismatch repair_Homo sapiens_hsa034303.28916924
7Pyrimidine metabolism_Homo sapiens_hsa002402.87717591
8Homologous recombination_Homo sapiens_hsa034402.76711523
9Spliceosome_Homo sapiens_hsa030402.75307732
10Protein export_Homo sapiens_hsa030602.69801639
11Nucleotide excision repair_Homo sapiens_hsa034202.65221092
12* RNA transport_Homo sapiens_hsa030132.47537534
13Basal transcription factors_Homo sapiens_hsa030222.47019171
14Base excision repair_Homo sapiens_hsa034102.34622593
15Non-homologous end-joining_Homo sapiens_hsa034502.33478114
16Oxidative phosphorylation_Homo sapiens_hsa001902.24121805
17Parkinsons disease_Homo sapiens_hsa050122.06300964
18Fanconi anemia pathway_Homo sapiens_hsa034602.02286830
19RNA degradation_Homo sapiens_hsa030181.92943634
20Purine metabolism_Homo sapiens_hsa002301.81917158
21Cell cycle_Homo sapiens_hsa041101.81059601
22Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.78053174
23Huntingtons disease_Homo sapiens_hsa050161.77201727
24One carbon pool by folate_Homo sapiens_hsa006701.53906112
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.51168063
26Folate biosynthesis_Homo sapiens_hsa007901.43262238
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.38689200
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.38279953
29Vitamin B6 metabolism_Homo sapiens_hsa007501.29247066
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.21100589
31Alzheimers disease_Homo sapiens_hsa050101.18850334
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.18540717
33Butanoate metabolism_Homo sapiens_hsa006501.16568245
34Peroxisome_Homo sapiens_hsa041461.14841256
35Propanoate metabolism_Homo sapiens_hsa006401.14335414
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.13956294
37Phototransduction_Homo sapiens_hsa047441.12490773
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.10557326
39Cysteine and methionine metabolism_Homo sapiens_hsa002701.02379852
40p53 signaling pathway_Homo sapiens_hsa041151.02229310
41mRNA surveillance pathway_Homo sapiens_hsa030150.99375753
42Epstein-Barr virus infection_Homo sapiens_hsa051690.96557820
43Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90547839
44SNARE interactions in vesicular transport_Homo sapiens_hsa041300.89495263
45Collecting duct acid secretion_Homo sapiens_hsa049660.89234613
46Caffeine metabolism_Homo sapiens_hsa002320.88958416
47Pentose phosphate pathway_Homo sapiens_hsa000300.86970847
48Glutathione metabolism_Homo sapiens_hsa004800.81265406
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77963963
50Nitrogen metabolism_Homo sapiens_hsa009100.76998615
51Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76115027
52Regulation of autophagy_Homo sapiens_hsa041400.72512606
53Arachidonic acid metabolism_Homo sapiens_hsa005900.72272587
54Fatty acid elongation_Homo sapiens_hsa000620.71248256
55Tryptophan metabolism_Homo sapiens_hsa003800.69817701
56Metabolic pathways_Homo sapiens_hsa011000.69636223
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.69484592
58Linoleic acid metabolism_Homo sapiens_hsa005910.68283071
59N-Glycan biosynthesis_Homo sapiens_hsa005100.67996094
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.60077448
61Steroid hormone biosynthesis_Homo sapiens_hsa001400.56547771
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.56153822
63Retinol metabolism_Homo sapiens_hsa008300.55909689
64Selenocompound metabolism_Homo sapiens_hsa004500.55171265
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55094817
66Sphingolipid metabolism_Homo sapiens_hsa006000.54182672
67Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.53591655
68Oocyte meiosis_Homo sapiens_hsa041140.50714873
69Antigen processing and presentation_Homo sapiens_hsa046120.49803673
70Systemic lupus erythematosus_Homo sapiens_hsa053220.49717868
71Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.49394105
72Herpes simplex infection_Homo sapiens_hsa051680.46818268
73alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.44914008
74Steroid biosynthesis_Homo sapiens_hsa001000.41856873
75Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.41349388
76Sulfur relay system_Homo sapiens_hsa041220.41158944
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.39752626
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38680445
79Ether lipid metabolism_Homo sapiens_hsa005650.37115415
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.36768069
81Cardiac muscle contraction_Homo sapiens_hsa042600.35487326
82Viral carcinogenesis_Homo sapiens_hsa052030.35171622
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34924399
84Fructose and mannose metabolism_Homo sapiens_hsa000510.34348901
85Fatty acid metabolism_Homo sapiens_hsa012120.34322547
86Cyanoamino acid metabolism_Homo sapiens_hsa004600.32472311
87Sulfur metabolism_Homo sapiens_hsa009200.32079551
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.30278208
89Primary immunodeficiency_Homo sapiens_hsa053400.29787171
90Biosynthesis of amino acids_Homo sapiens_hsa012300.29396003
91Rheumatoid arthritis_Homo sapiens_hsa053230.28788715
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.28611535
93beta-Alanine metabolism_Homo sapiens_hsa004100.28023249
94Maturity onset diabetes of the young_Homo sapiens_hsa049500.27962043
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26925619
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26911004
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.25362485
98Galactose metabolism_Homo sapiens_hsa000520.23180437
99Legionellosis_Homo sapiens_hsa051340.22392054
100Carbon metabolism_Homo sapiens_hsa012000.21250240
101Fatty acid degradation_Homo sapiens_hsa000710.21062222
102Arginine and proline metabolism_Homo sapiens_hsa003300.20853887
103Circadian rhythm_Homo sapiens_hsa047100.18718665
104Type I diabetes mellitus_Homo sapiens_hsa049400.18601610
105HTLV-I infection_Homo sapiens_hsa051660.18417938
106Autoimmune thyroid disease_Homo sapiens_hsa053200.13225090
107Hematopoietic cell lineage_Homo sapiens_hsa046400.12780520
108Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.10814777
109Glycerophospholipid metabolism_Homo sapiens_hsa005640.10674139
110Vibrio cholerae infection_Homo sapiens_hsa051100.10463729
111Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.10071408
112Alcoholism_Homo sapiens_hsa050340.08089835
113Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.06869947
114Pyruvate metabolism_Homo sapiens_hsa006200.06624395
115NOD-like receptor signaling pathway_Homo sapiens_hsa046210.05349243
116Intestinal immune network for IgA production_Homo sapiens_hsa046720.05226970
117Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.05135803
118Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.04739543
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.04363229
120Other glycan degradation_Homo sapiens_hsa005110.04302359
121Measles_Homo sapiens_hsa051620.03704844
122Chemical carcinogenesis_Homo sapiens_hsa052040.03655944
123Allograft rejection_Homo sapiens_hsa053300.03324190
124Vitamin digestion and absorption_Homo sapiens_hsa049770.02832572
125Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.02524831
126Tyrosine metabolism_Homo sapiens_hsa003500.02358513

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