RPRD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)5.26740130
2cytoplasmic mRNA processing body assembly (GO:0033962)4.64732950
3pre-miRNA processing (GO:0031054)4.54688911
4nuclear pore complex assembly (GO:0051292)4.40434104
5regulation of histone H3-K27 methylation (GO:0061085)4.38588798
6regulation of chromatin binding (GO:0035561)4.07039903
7histone H3-K4 trimethylation (GO:0080182)4.05663353
8regulation of RNA export from nucleus (GO:0046831)3.98805890
9negative regulation of translation, ncRNA-mediated (GO:0040033)3.97009548
10regulation of translation, ncRNA-mediated (GO:0045974)3.97009548
11negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.97009548
12histone H3-K4 methylation (GO:0051568)3.95513758
13nuclear pore organization (GO:0006999)3.71874315
14positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.63321144
15regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.63321144
16glucocorticoid receptor signaling pathway (GO:0042921)3.62386012
17positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.58860892
18regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.58860892
19insulin-like growth factor receptor signaling pathway (GO:0048009)3.53648340
20positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.52066462
21histone H3-K36 demethylation (GO:0070544)3.43463599
22negative regulation of histone methylation (GO:0031061)3.41140661
23stress granule assembly (GO:0034063)3.37904999
24regulation of nucleobase-containing compound transport (GO:0032239)3.31489536
25histone H3-K9 demethylation (GO:0033169)3.29323638
26NLS-bearing protein import into nucleus (GO:0006607)3.28109878
27negative regulation of cell killing (GO:0031342)3.25985015
28negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.25985015
29histone lysine methylation (GO:0034968)3.15868066
30peptidyl-lysine trimethylation (GO:0018023)3.14902815
31histone H3-K9 modification (GO:0061647)3.10910035
32pore complex assembly (GO:0046931)3.08263585
33phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.07563316
34corticosteroid receptor signaling pathway (GO:0031958)2.98776910
35positive regulation of mRNA catabolic process (GO:0061014)2.98142405
36embryonic eye morphogenesis (GO:0048048)2.95935157
37regulation of DNA endoreduplication (GO:0032875)2.92109482
38RNA localization (GO:0006403)2.91693947
39histone lysine demethylation (GO:0070076)2.84509287
40embryonic camera-type eye morphogenesis (GO:0048596)2.84190119
41regulation of mRNA catabolic process (GO:0061013)2.81476123
42positive regulation of histone deacetylation (GO:0031065)2.80635283
43retrograde transport, vesicle recycling within Golgi (GO:0000301)2.80441184
44N-terminal protein amino acid acetylation (GO:0006474)2.79283829
45mitotic chromosome condensation (GO:0007076)2.76687372
46histone deubiquitination (GO:0016578)2.73393573
47histone H4-K16 acetylation (GO:0043984)2.72435228
48histone H3-K9 methylation (GO:0051567)2.72068926
49regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.69522712
50ear development (GO:0043583)2.68878823
51histone demethylation (GO:0016577)2.68437818
52DNA unwinding involved in DNA replication (GO:0006268)2.67259952
53regulation of sister chromatid cohesion (GO:0007063)2.66647611
54hippo signaling (GO:0035329)2.66492804
55peptidyl-lysine dimethylation (GO:0018027)2.66490768
56spliceosomal tri-snRNP complex assembly (GO:0000244)2.66308272
57phosphatidylinositol dephosphorylation (GO:0046856)2.65705131
58regulation of histone H3-K4 methylation (GO:0051569)2.65668003
59positive regulation of gene expression, epigenetic (GO:0045815)2.65026013
60protein targeting to Golgi (GO:0000042)2.64981327
61camera-type eye morphogenesis (GO:0048593)2.64256241
62histone methylation (GO:0016571)2.63830768
63embryonic process involved in female pregnancy (GO:0060136)2.63575262
64regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.62678600
65regulation of histone methylation (GO:0031060)2.59186536
66regulation of NFAT protein import into nucleus (GO:0051532)2.54639511
67protein-DNA complex disassembly (GO:0032986)2.54406325
68nucleosome disassembly (GO:0006337)2.54406325
69regulation of fatty acid beta-oxidation (GO:0031998)2.54210593
70intracellular estrogen receptor signaling pathway (GO:0030520)2.53200328
71embryonic retina morphogenesis in camera-type eye (GO:0060059)2.53005968
72cell-substrate adherens junction assembly (GO:0007045)2.51530733
73focal adhesion assembly (GO:0048041)2.51530733
74positive regulation of tolerance induction (GO:0002645)2.51440353
75heart morphogenesis (GO:0003007)2.51056921
76dosage compensation (GO:0007549)2.50698001
77eye morphogenesis (GO:0048592)2.50166226
78histone H4 acetylation (GO:0043967)2.49506538
79peptidyl-threonine phosphorylation (GO:0018107)2.49437145
80protein localization to microtubule (GO:0035372)2.48947950
81protein demethylation (GO:0006482)2.48788534
82protein dealkylation (GO:0008214)2.48788534
83positive regulation of mRNA 3-end processing (GO:0031442)2.48223059
84positive T cell selection (GO:0043368)2.46328376
85negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.44565606
86mRNA splice site selection (GO:0006376)2.44396796
87peptidyl-lysine methylation (GO:0018022)2.44140996
88phospholipid dephosphorylation (GO:0046839)2.43941980
89regulation of ARF protein signal transduction (GO:0032012)2.43756981
90Golgi to endosome transport (GO:0006895)2.43704188
91adherens junction assembly (GO:0034333)2.43702858
92regulation of mRNA 3-end processing (GO:0031440)2.43407435
93V(D)J recombination (GO:0033151)2.41662446
94apical protein localization (GO:0045176)2.41443289
95positive regulation by host of viral transcription (GO:0043923)2.41161057
96trophectodermal cell differentiation (GO:0001829)2.39272135
97sister chromatid cohesion (GO:0007062)2.38950314
98regulation of histone H3-K9 methylation (GO:0051570)2.38491946
99DNA methylation (GO:0006306)2.38119173
100DNA alkylation (GO:0006305)2.38119173
101establishment of protein localization to Golgi (GO:0072600)2.37553185
102negative regulation of histone modification (GO:0031057)2.37081058
103positive regulation of DNA-templated transcription, initiation (GO:2000144)2.36331358
104regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.36320795
105body morphogenesis (GO:0010171)2.34808589
106positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.33831414
107negative regulation of glycogen biosynthetic process (GO:0045719)2.33143746
108positive thymic T cell selection (GO:0045059)2.32402967
109peptidyl-lysine acetylation (GO:0018394)2.31080798
110peripheral nervous system neuron development (GO:0048935)2.30536283
111positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.30133425
112histone mRNA catabolic process (GO:0071044)2.29577398
113nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.28990778
114positive regulation of histone H3-K4 methylation (GO:0051571)2.28491405
115histone H4-K5 acetylation (GO:0043981)2.27772979
116histone H4-K8 acetylation (GO:0043982)2.27772979
117negative regulation of chromatin modification (GO:1903309)2.27674824
118regulation of clathrin-mediated endocytosis (GO:2000369)2.26952591
119positive regulation of mRNA processing (GO:0050685)2.26630712
120peptidyl-threonine modification (GO:0018210)2.26382150
121monoubiquitinated protein deubiquitination (GO:0035520)2.24032260
122embryonic hemopoiesis (GO:0035162)2.23709434
123RNA stabilization (GO:0043489)2.23520456
124mRNA stabilization (GO:0048255)2.23520456
125histone acetylation (GO:0016573)2.22864740
126neural tube closure (GO:0001843)2.21154959
127regulation of protein deacetylation (GO:0090311)2.20110633
128gene silencing by RNA (GO:0031047)2.19657282
129tolerance induction (GO:0002507)2.19125907
130tube closure (GO:0060606)2.16813633
131positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.15982454
132positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.15982454
133positive regulation of mitotic sister chromatid separation (GO:1901970)2.15982454
134interkinetic nuclear migration (GO:0022027)2.15702447
135regulation of telomere maintenance (GO:0032204)2.15189350
136internal peptidyl-lysine acetylation (GO:0018393)2.12646012
137definitive hemopoiesis (GO:0060216)2.11296855
138regulation of histone deacetylation (GO:0031063)2.11291701
139positive regulation of mRNA metabolic process (GO:1903313)2.10056891
140gene silencing (GO:0016458)2.09920333
141negative regulation of DNA repair (GO:0045738)2.09795983
142negative thymic T cell selection (GO:0045060)2.08334438
143negative T cell selection (GO:0043383)2.07655219
144negative regulation of circadian rhythm (GO:0042754)2.07500369
145histone H4-K12 acetylation (GO:0043983)2.07104790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.05712685
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.23400979
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.20049961
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.20008928
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.07736946
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.00911448
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.93685289
8EZH2_22144423_ChIP-Seq_EOC_Human2.89343028
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.72042611
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.63456135
11BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.60705840
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.58321781
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.50570032
14* MYC_22102868_ChIP-Seq_BL_Human2.39750483
15STAT6_21828071_ChIP-Seq_BEAS2B_Human2.25042839
16* TFAP2C_20629094_ChIP-Seq_MCF-7_Human2.24345973
17CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.22855090
18DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.07395021
19TP63_19390658_ChIP-ChIP_HaCaT_Human2.03735468
20STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.03691624
21TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.99062120
22RBPJ_22232070_ChIP-Seq_NCS_Mouse1.92291100
23TCF7_22412390_ChIP-Seq_EML_Mouse1.90909096
24SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.84556269
25FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.83522351
26SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.76327520
27AR_21572438_ChIP-Seq_LNCaP_Human1.75023641
28ZNF217_24962896_ChIP-Seq_MCF-7_Human1.71477506
29* CHD1_26751641_Chip-Seq_LNCaP_Human1.69799178
30ESR1_15608294_ChIP-ChIP_MCF-7_Human1.68118036
31TP53_16413492_ChIP-PET_HCT116_Human1.65826549
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.63349627
33RING1B_27294783_Chip-Seq_NPCs_Mouse1.60712845
34WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.60703736
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.59808568
36SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.58069135
37EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.56269969
38ZFP281_27345836_Chip-Seq_ESCs_Mouse1.54783907
39* RUNX_20019798_ChIP-Seq_JUKART_Human1.54517720
40KDM2B_26808549_Chip-Seq_DND41_Human1.53806146
41* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.53684828
42CTNNB1_20460455_ChIP-Seq_HCT116_Human1.52244241
43FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.51847875
44* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.48372216
45* ISL1_27105846_Chip-Seq_CPCs_Mouse1.45056724
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.44359013
47TBX3_20139965_ChIP-Seq_ESCs_Mouse1.43207095
48STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42838365
49TBX3_20139965_ChIP-Seq_MESCs_Mouse1.42093669
50E2F4_17652178_ChIP-ChIP_JURKAT_Human1.41680972
51ESR2_21235772_ChIP-Seq_MCF-7_Human1.40706931
52RUNX1_27514584_Chip-Seq_MCF-7_Human1.40499066
53KDM2B_26808549_Chip-Seq_JURKAT_Human1.40040303
54YAP1_20516196_ChIP-Seq_MESCs_Mouse1.34665369
55RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.34627762
56ESR1_20079471_ChIP-ChIP_T-47D_Human1.32747392
57HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.32053138
58ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.30396676
59EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30392315
60PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29399405
61AR_21909140_ChIP-Seq_LNCAP_Human1.29184844
62ARNT_22903824_ChIP-Seq_MCF-7_Human1.28676848
63* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.27002295
64FUS_26573619_Chip-Seq_HEK293_Human1.25313740
65SOX9_24532713_ChIP-Seq_HFSC_Mouse1.24380230
66* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.23556016
67TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.23400642
68KDM2B_26808549_Chip-Seq_SUP-B15_Human1.22464750
69NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.21516328
70DROSHA_22980978_ChIP-Seq_HELA_Human1.21367460
71* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.20098244
72WT1_19549856_ChIP-ChIP_CCG9911_Human1.17605437
73EWS_26573619_Chip-Seq_HEK293_Human1.17246434
74* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16982615
75KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16698314
76WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16312924
77NFIB_24661679_ChIP-Seq_LUNG_Mouse1.15736218
78BP1_19119308_ChIP-ChIP_Hs578T_Human1.15708439
79AHR_22903824_ChIP-Seq_MCF-7_Human1.14708036
80STAT3_23295773_ChIP-Seq_U87_Human1.14577324
81ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14193087
82POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14152894
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14152894
84TCF4_23295773_ChIP-Seq_U87_Human1.13619150
85* CREB1_26743006_Chip-Seq_LNCaP_Human1.12580131
86RNF2_27304074_Chip-Seq_ESCs_Mouse1.12493643
87NANOG_21062744_ChIP-ChIP_HESCs_Human1.12136717
88* FOXA2_19822575_ChIP-Seq_HepG2_Human1.10839464
89RARB_27405468_Chip-Seq_BRAIN_Mouse1.10337883
90DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.09375140
91* KDM5A_27292631_Chip-Seq_BREAST_Human1.09021484
92NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.06594402
93ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05637326
94SMAD4_21799915_ChIP-Seq_A2780_Human1.05172184
95TCF4_18268006_ChIP-ChIP_LS174T_Human1.05149309
96JARID2_20064375_ChIP-Seq_MESCs_Mouse1.04193215
97GBX2_23144817_ChIP-Seq_PC3_Human1.04138289
98CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.03967240
99AR_19668381_ChIP-Seq_PC3_Human1.03614039
100EZH2_27304074_Chip-Seq_ESCs_Mouse1.03350680
101BRD4_25478319_ChIP-Seq_HGPS_Human1.02881565
102VDR_21846776_ChIP-Seq_THP-1_Human1.02811051
103* RACK7_27058665_Chip-Seq_MCF-7_Human1.02711954
104CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.02660996
105PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02184675
106RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.01904978
107ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00823784
108* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00671171
109ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00462054
110PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00205280
111NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.99229325
112CIITA_25753668_ChIP-Seq_RAJI_Human0.98932965
113SOX2_21211035_ChIP-Seq_LN229_Gbm0.98773931
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.98630214
115CBX2_27304074_Chip-Seq_ESCs_Mouse0.96986457
116ZNF274_21170338_ChIP-Seq_K562_Hela0.96801467
117KDM2B_26808549_Chip-Seq_K562_Human0.94245026
118SOX2_27498859_Chip-Seq_STOMACH_Mouse0.94173859
119POU3F2_20337985_ChIP-ChIP_501MEL_Human0.93380049
120MYB_26560356_Chip-Seq_TH1_Human0.92701826
121SCL_19346495_ChIP-Seq_HPC-7_Human0.92426482
122E2F1_21310950_ChIP-Seq_MCF-7_Human0.92043786
123PIAS1_25552417_ChIP-Seq_VCAP_Human0.91938282
124MYB_26560356_Chip-Seq_TH2_Human0.91460197
125FOXM1_26456572_ChIP-Seq_MCF-7_Human0.91123649
126SOX9_26525672_Chip-Seq_HEART_Mouse0.90993705
127POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.90730402
128FOXO3_23340844_ChIP-Seq_DLD1_Human0.90440540
129ESR1_21235772_ChIP-Seq_MCF-7_Human0.90373796
130SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.90338674
131SMAD3_21741376_ChIP-Seq_EPCs_Human0.89912434
132* UTX_26944678_Chip-Seq_JUKART_Human0.89162881
133GATA1_26923725_Chip-Seq_HPCs_Mouse0.88896877
134STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.88714123
135TP53_20018659_ChIP-ChIP_R1E_Mouse0.88582698
136EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.88502713
137TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.87921742
138PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.87616755
139P300_19829295_ChIP-Seq_ESCs_Human0.86773574

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002009_preneoplasia4.58130067
2MP0000569_abnormal_digit_pigmentation3.73499437
3MP0005076_abnormal_cell_differentiation3.27689452
4MP0003121_genomic_imprinting2.64989855
5MP0003122_maternal_imprinting2.44043229
6MP0008961_abnormal_basal_metabolism2.39718787
7MP0003787_abnormal_imprinting2.37753039
8MP0008057_abnormal_DNA_replication2.25541962
9MP0010352_gastrointestinal_tract_polyps2.14332142
10MP0004808_abnormal_hematopoietic_stem2.13496617
11MP0002249_abnormal_larynx_morphology2.12746007
12MP0008877_abnormal_DNA_methylation2.10524474
13MP0002396_abnormal_hematopoietic_system2.09446203
14MP0003300_gastrointestinal_ulcer2.05533023
15MP0003890_abnormal_embryonic-extraembry2.01014524
16MP0004233_abnormal_muscle_weight1.99698371
17MP0000566_synostosis1.95929329
18MP0002166_altered_tumor_susceptibility1.90604173
19MP0004185_abnormal_adipocyte_glucose1.69297409
20MP0009703_decreased_birth_body1.67720777
21MP0009278_abnormal_bone_marrow1.67516027
22MP0001348_abnormal_lacrimal_gland1.64735241
23MP0002877_abnormal_melanocyte_morpholog1.63187697
24MP0004197_abnormal_fetal_growth/weight/1.62911386
25MP0003091_abnormal_cell_migration1.61517898
26MP0001346_abnormal_lacrimal_gland1.59529517
27MP0002084_abnormal_developmental_patter1.59359938
28MP0003984_embryonic_growth_retardation1.55593752
29MP0002088_abnormal_embryonic_growth/wei1.54040388
30MP0001293_anophthalmia1.52545372
31MP0003705_abnormal_hypodermis_morpholog1.51828677
32MP0001299_abnormal_eye_distance/1.51554122
33MP0005423_abnormal_somatic_nervous1.47681910
34MP0003045_fibrosis1.47022066
35MP0000428_abnormal_craniofacial_morphol1.46484481
36MP0009780_abnormal_chondrocyte_physiolo1.46251206
37MP0003942_abnormal_urinary_system1.45210923
38MP0005380_embryogenesis_phenotype1.43707586
39MP0001672_abnormal_embryogenesis/_devel1.43707586
40MP0004145_abnormal_muscle_electrophysio1.41423233
41MP0000350_abnormal_cell_proliferation1.40435537
42MP0000733_abnormal_muscle_development1.38787538
43MP0010307_abnormal_tumor_latency1.37963960
44MP0003935_abnormal_craniofacial_develop1.37896444
45MP0002086_abnormal_extraembryonic_tissu1.36935480
46MP0001502_abnormal_circadian_rhythm1.36125096
47MP0002925_abnormal_cardiovascular_devel1.33598542
48MP0000534_abnormal_ureter_morphology1.32641724
49MP0000703_abnormal_thymus_morphology1.29877155
50MP0003828_pulmonary_edema1.28080874
51MP0002085_abnormal_embryonic_tissue1.25522190
52MP0001697_abnormal_embryo_size1.23450294
53MP0010630_abnormal_cardiac_muscle1.20462579
54MP0010094_abnormal_chromosome_stability1.19572673
55MP0003950_abnormal_plasma_membrane1.18256439
56MP0003077_abnormal_cell_cycle1.17961127
57MP0004134_abnormal_chest_morphology1.17535000
58MP0000383_abnormal_hair_follicle1.16521931
59MP0009672_abnormal_birth_weight1.12867345
60MP0000266_abnormal_heart_morphology1.12183529
61MP0004130_abnormal_muscle_cell1.11206223
62MP0000003_abnormal_adipose_tissue1.08027489
63MP0004859_abnormal_synaptic_plasticity1.06050808
64MP0003861_abnormal_nervous_system1.04476416
65MP0005187_abnormal_penis_morphology1.03541224
66MP0002006_tumorigenesis1.01984174
67MP0003763_abnormal_thymus_physiology1.01580294
68MP0001784_abnormal_fluid_regulation1.01137768
69MP0000432_abnormal_head_morphology1.00870473
70MP0003115_abnormal_respiratory_system1.00825516
71MP0005666_abnormal_adipose_tissue1.00779309
72MP0000537_abnormal_urethra_morphology1.00486975
73MP0001879_abnormal_lymphatic_vessel1.00299529
74MP0004084_abnormal_cardiac_muscle0.99909655
75MP0003567_abnormal_fetal_cardiomyocyte0.99685128
76MP0001730_embryonic_growth_arrest0.99525732
77MP0002114_abnormal_axial_skeleton0.98916823
78MP0002653_abnormal_ependyma_morphology0.98619900
79MP0003943_abnormal_hepatobiliary_system0.96687274
80MP0003123_paternal_imprinting0.95663623
81MP0002928_abnormal_bile_duct0.95341311
82MP0002092_abnormal_eye_morphology0.94064126
83MP0000631_abnormal_neuroendocrine_gland0.93770321
84MP0006292_abnormal_olfactory_placode0.93432255
85MP0002098_abnormal_vibrissa_morphology0.93050174
86MP0003693_abnormal_embryo_hatching0.92902395
87MP0004270_analgesia0.92423533
88MP0003111_abnormal_nucleus_morphology0.92098028
89MP0003755_abnormal_palate_morphology0.90726923
90MP0002116_abnormal_craniofacial_bone0.89836788
91MP0001340_abnormal_eyelid_morphology0.89301211
92MP0000678_abnormal_parathyroid_gland0.88767710
93MP0006138_congestive_heart_failure0.88566209
94MP0004043_abnormal_pH_regulation0.87873768
95MP0002234_abnormal_pharynx_morphology0.87233042
96MP0009250_abnormal_appendicular_skeleto0.86482171
97MP0005397_hematopoietic_system_phenotyp0.85209728
98MP0001545_abnormal_hematopoietic_system0.85209728
99MP0000759_abnormal_skeletal_muscle0.83410874
100MP0001286_abnormal_eye_development0.82687883
101MP0004484_altered_response_of0.82116485
102MP0000778_abnormal_nervous_system0.82076316
103MP0005310_abnormal_salivary_gland0.81961876
104MP0003283_abnormal_digestive_organ0.81943357
105MP0005248_abnormal_Harderian_gland0.81641461
106MP0005623_abnormal_meninges_morphology0.80764458
107MP0009115_abnormal_fat_cell0.80622083
108MP0004264_abnormal_extraembryonic_tissu0.80510002
109MP0002932_abnormal_joint_morphology0.79824522
110MP0002398_abnormal_bone_marrow0.79385084
111MP0003938_abnormal_ear_development0.78863592
112MP0005174_abnormal_tail_pigmentation0.78518029
113MP0008058_abnormal_DNA_repair0.77617254
114MP0008770_decreased_survivor_rate0.77222344
115MP0003119_abnormal_digestive_system0.76875967
116MP0003937_abnormal_limbs/digits/tail_de0.76640954
117MP0005646_abnormal_pituitary_gland0.75911346
118MP0000377_abnormal_hair_follicle0.75663515
119MP0000955_abnormal_spinal_cord0.75567918
120MP0002080_prenatal_lethality0.75170983
121MP0001188_hyperpigmentation0.75086020
122MP0002152_abnormal_brain_morphology0.73846689
123MP0002160_abnormal_reproductive_system0.73594914
124MP0010678_abnormal_skin_adnexa0.72683590
125MP0002108_abnormal_muscle_morphology0.72527611
126MP0008569_lethality_at_weaning0.72237613
127MP0001915_intracranial_hemorrhage0.71452864
128MP0002081_perinatal_lethality0.71301358
129MP0002697_abnormal_eye_size0.70688947
130MP0009053_abnormal_anal_canal0.69630034
131MP0005409_darkened_coat_color0.68631706
132MP0005621_abnormal_cell_physiology0.68080706
133MP0004087_abnormal_muscle_fiber0.67162764
134MP0010234_abnormal_vibrissa_follicle0.66672921
135MP0002089_abnormal_postnatal_growth/wei0.64008990
136MP0003303_peritoneal_inflammation0.62068317
137MP0005384_cellular_phenotype0.61390813
138MP0005375_adipose_tissue_phenotype0.61049259

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)4.92240577
2Volvulus (HP:0002580)4.72895572
3Abnormality of the fingertips (HP:0001211)4.05586548
4Macroorchidism (HP:0000053)3.81983278
5Short 4th metacarpal (HP:0010044)3.15929641
6Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.15929641
7Long eyelashes (HP:0000527)3.14726457
8Narrow palate (HP:0000189)2.98809411
9Abnormality of the nasal septum (HP:0000419)2.82959389
10Urethral obstruction (HP:0000796)2.82679262
11Genetic anticipation (HP:0003743)2.74962865
12Abnormality of the astrocytes (HP:0100707)2.61759533
13Astrocytoma (HP:0009592)2.61759533
14Truncal obesity (HP:0001956)2.59597732
15Abnormality of the labia minora (HP:0012880)2.53333297
16Obsessive-compulsive behavior (HP:0000722)2.52240524
17Trigonocephaly (HP:0000243)2.47273703
18Menstrual irregularities (HP:0000858)2.45751658
19Abnormal hair whorl (HP:0010721)2.45217538
20Abnormality of the aortic arch (HP:0012303)2.44575369
21Ectopic kidney (HP:0000086)2.42291125
22Ependymoma (HP:0002888)2.40289962
23Septate vagina (HP:0001153)2.39263982
24Abnormality of the distal phalanx of the thumb (HP:0009617)2.37673538
25Heterotopia (HP:0002282)2.37622750
26Prominent nose (HP:0000448)2.36035055
27Absent frontal sinuses (HP:0002688)2.32780693
28Insidious onset (HP:0003587)2.31734311
29Termporal pattern (HP:0011008)2.31734311
30Broad face (HP:0000283)2.28211771
31Increased nuchal translucency (HP:0010880)2.26334444
32Supernumerary ribs (HP:0005815)2.26239786
33Anal stenosis (HP:0002025)2.26167301
34Dislocated radial head (HP:0003083)2.24923646
35Abnormality of the columella (HP:0009929)2.23680442
36Abnormal number of incisors (HP:0011064)2.21026527
37Broad thumb (HP:0011304)2.19380700
38Acute myeloid leukemia (HP:0004808)2.17898988
39Abnormality of the radial head (HP:0003995)2.17736802
40Aqueductal stenosis (HP:0002410)2.16738207
41Abnormality of the phalanges of the hallux (HP:0010057)2.16326221
42Proximal placement of thumb (HP:0009623)2.13691767
43Glioma (HP:0009733)2.12011324
44Papillary thyroid carcinoma (HP:0002895)2.11727875
45Deviation of the thumb (HP:0009603)2.11568915
46Dysmetric saccades (HP:0000641)2.11351735
47Hyperkalemia (HP:0002153)2.11350818
48Abnormality of the 4th metacarpal (HP:0010012)2.07173639
49Ankyloglossia (HP:0010296)2.06273800
50Syringomyelia (HP:0003396)2.06262211
51Spinal cord lesions (HP:0100561)2.06262211
52Hypoplasia of the maxilla (HP:0000327)2.06254066
53Thick eyebrow (HP:0000574)2.05108974
54High anterior hairline (HP:0009890)2.04781760
55Cutis marmorata (HP:0000965)2.04543079
56Sparse lateral eyebrow (HP:0005338)2.02974737
57Hypoplastic labia majora (HP:0000059)2.02841280
58Germ cell neoplasia (HP:0100728)2.01759159
59Abnormality of chromosome segregation (HP:0002916)2.01486613
60Vertebral arch anomaly (HP:0008438)2.00424972
61Neoplasm of the oral cavity (HP:0100649)2.00178988
62Supernumerary bones of the axial skeleton (HP:0009144)1.99689200
63Skin tags (HP:0010609)1.99399807
64Low anterior hairline (HP:0000294)1.99048607
65Deep philtrum (HP:0002002)1.98333844
66Neonatal hypoglycemia (HP:0001998)1.96546365
67Depressed nasal tip (HP:0000437)1.95701767
68Cystic hygroma (HP:0000476)1.95247245
69Smooth philtrum (HP:0000319)1.93503847
70Abnormality of oral frenula (HP:0000190)1.93125792
71Facial hemangioma (HP:0000329)1.93025572
72Abnormality of the parietal bone (HP:0002696)1.90708534
73Abnormality of the left ventricular outflow tract (HP:0011103)1.90543073
74Subaortic stenosis (HP:0001682)1.90543073
75Thyroid carcinoma (HP:0002890)1.89037062
76Hypercortisolism (HP:0001578)1.86831494
77Midline defect of the nose (HP:0004122)1.86692822
78Sleep apnea (HP:0010535)1.86008075
79Shallow orbits (HP:0000586)1.85975674
80Limited elbow extension (HP:0001377)1.82850775
81Abnormality of the intervertebral disk (HP:0005108)1.82840680
82Neoplasm of the heart (HP:0100544)1.82589680
83Lip pit (HP:0100267)1.82334811
84Sacral dimple (HP:0000960)1.81483024
85Intestinal fistula (HP:0100819)1.81438695
86Tapered finger (HP:0001182)1.80856881
87Abnormality of the labia majora (HP:0012881)1.80030392
88Hamartoma (HP:0010566)1.79889261
89Increased number of teeth (HP:0011069)1.78911058
90Overgrowth (HP:0001548)1.78816291
91Pseudobulbar signs (HP:0002200)1.78722581
92Drooling (HP:0002307)1.77825163
93Excessive salivation (HP:0003781)1.77825163
94Transitional cell carcinoma of the bladder (HP:0006740)1.77251164
95Asymmetry of the thorax (HP:0001555)1.76494050
96Abnormality of the incisor (HP:0000676)1.76126390
97Attention deficit hyperactivity disorder (HP:0007018)1.76084170
98Skin pits (HP:0100276)1.75937608
99Cubitus valgus (HP:0002967)1.75893710
100Hypoplastic ischia (HP:0003175)1.74169415
101Open mouth (HP:0000194)1.71904951
102Oligodactyly (hands) (HP:0001180)1.71884241
103Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.70815928
104Sandal gap (HP:0001852)1.69671001
105Skull defect (HP:0001362)1.69005411
106Deep palmar crease (HP:0006191)1.68751561
107Pheochromocytoma (HP:0002666)1.68588205
108Aplasia/Hypoplasia of the sternum (HP:0006714)1.68507543
109Short phalanx of the thumb (HP:0009660)1.68378997
110Hyperacusis (HP:0010780)1.68277191
111Large earlobe (HP:0009748)1.66648519
112Flat acetabular roof (HP:0003180)1.66576755
113Enlarged penis (HP:0000040)1.65093287
114Widely spaced teeth (HP:0000687)1.64761018
115Sporadic (HP:0003745)1.64693951
116Low posterior hairline (HP:0002162)1.64227308
117Oligodontia (HP:0000677)1.64055593
118Short 1st metacarpal (HP:0010034)1.63598953
119Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.63598953
120Anteriorly placed anus (HP:0001545)1.63404669
121Aortic aneurysm (HP:0004942)1.62778182
122Gastrointestinal carcinoma (HP:0002672)1.62465241
123Malignant gastrointestinal tract tumors (HP:0006749)1.62465241
124Thin upper lip vermilion (HP:0000219)1.62083953
125Overlapping toe (HP:0001845)1.61898920
126Broad phalanges of the hand (HP:0009768)1.61837327
127Laryngomalacia (HP:0001601)1.61734819
128Deformed sella turcica (HP:0002681)1.61611316
129Broad finger (HP:0001500)1.59130054
130Impaired smooth pursuit (HP:0007772)1.58717131
131Shawl scrotum (HP:0000049)1.58187043
132Neoplasm of striated muscle (HP:0009728)1.58095212
133Deeply set eye (HP:0000490)1.56130135
134Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.56049021
135Hepatoblastoma (HP:0002884)1.55992907
136Preauricular skin tag (HP:0000384)1.55934882
137Morphological abnormality of the middle ear (HP:0008609)1.55852401
138Precocious puberty (HP:0000826)1.55246834
139Curly hair (HP:0002212)1.54832858
140Synophrys (HP:0000664)1.54579477
141Spina bifida occulta (HP:0003298)1.53925433
142Bladder carcinoma (HP:0002862)1.53877598
143Bladder neoplasm (HP:0009725)1.53877598
144Papilledema (HP:0001085)1.53593364
145Broad palm (HP:0001169)1.53566281
146Cafe-au-lait spot (HP:0000957)1.53323055
147Pointed chin (HP:0000307)1.52993092
148Intestinal malrotation (HP:0002566)1.52916429
149Cerebral aneurysm (HP:0004944)1.52095788
150Tented upper lip vermilion (HP:0010804)1.51747143

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.86402786
2BRD43.57206394
3CAMK1G2.84162605
4CAMK1D2.81730426
5TRIB32.62674905
6MAP3K102.60818792
7SIK32.36780471
8FGFR22.16061557
9SMG12.06368075
10ICK1.91616204
11TYRO31.89972355
12CDK91.85754929
13CDC71.85716283
14LATS11.83772965
15NTRK21.83395599
16FGFR31.81715939
17SIK11.73877883
18DMPK1.69816255
19TAF11.60507931
20KSR11.53656004
21MTOR1.49073265
22CDK61.37565706
23SGK31.34296444
24MAP3K21.30116285
25PRKD31.23338266
26SGK21.23103075
27STK31.22019977
28PRKD21.19268001
29ITK1.19084776
30MELK1.13586186
31SIK21.12818026
32PNCK1.10821626
33AKT31.10109102
34EEF2K1.10092943
35WNK11.07957541
36INSRR1.05763356
37TNK21.05300867
38PDGFRB1.04493919
39ALK1.04322907
40PTK61.00221853
41PDGFRA0.98968919
42FGFR40.96832170
43FGFR10.96618735
44ATM0.92079108
45CDK40.91687687
46MAPK100.90624468
47FRK0.87546086
48RPS6KB20.87088368
49YES10.85294369
50RIPK10.85165188
51MAP4K10.83762582
52CHEK10.83699377
53NTRK30.83276599
54STK100.83267926
55CSNK1A1L0.81955698
56MAPK120.80177045
57UHMK10.78514897
58CDC42BPA0.76993811
59MARK20.76773812
60CDK20.74285402
61JAK10.74150569
62PRKCH0.73836937
63CAMK40.72745775
64STK110.72184561
65HIPK20.70901468
66ERN10.70523400
67MAPK140.70195418
68STK380.70097973
69NTRK10.69334109
70NLK0.69133306
71MAP3K70.67692107
72TTN0.66733925
73CSNK1D0.66442155
74ATR0.65294996
75CHUK0.65172113
76GRK60.65157877
77MAPK70.65037829
78SGK10.64934272
79GSK3B0.63954768
80TNIK0.63480365
81MAP3K40.63083442
82ERBB20.62900048
83MARK10.62856572
84MAPK80.61788463
85CDK10.61602693
86MAP2K20.61268642
87MAP3K90.61112787
88PIM10.59402044
89NEK20.59293589
90MAPK10.57326447
91EPHB10.57316638
92MARK30.56877689
93PKN20.56874302
94RPS6KL10.56834855
95RPS6KC10.56834855
96STK40.56378900
97RPS6KB10.56095751
98MET0.55501385
99STK240.54129512
100PRKAA10.53549637
101RPS6KA20.53313064
102SGK2230.53268519
103SGK4940.53268519
104CAMKK10.52549117
105KSR20.51589826
106PASK0.50246151
107PRPF4B0.49599236
108MAPK110.49484542
109TAOK10.49110745
110PIK3CA0.48456850
111PRKDC0.48099084
112RPS6KA30.47937297
113EGFR0.47557411
114SCYL20.47474641
115CHEK20.47425913
116CAMK10.47293931
117CSNK1E0.47266099
118MKNK20.44672361
119RPS6KA60.43537838
120PRKCQ0.43203056
121PHKG10.42878111
122PHKG20.42878111
123TRPM70.42757022
124RET0.42069404
125BMPR1B0.41729738
126MAPK90.41562656
127AKT10.40941484
128CDK70.38865874
129NEK60.38714781
130CDK30.38603944
131PLK30.38327520
132JAK30.37375719
133EPHA30.36653217

Predicted pathways (KEGG)

RankGene SetZ-score
1Dorso-ventral axis formation_Homo sapiens_hsa043201.79614572
2Lysine degradation_Homo sapiens_hsa003101.73017012
3Adherens junction_Homo sapiens_hsa045201.56504658
4Thyroid hormone signaling pathway_Homo sapiens_hsa049191.56169408
5MicroRNAs in cancer_Homo sapiens_hsa052061.53963232
6Long-term potentiation_Homo sapiens_hsa047201.52073206
7mTOR signaling pathway_Homo sapiens_hsa041501.47306140
8Chronic myeloid leukemia_Homo sapiens_hsa052201.46753480
9mRNA surveillance pathway_Homo sapiens_hsa030151.43289255
10Colorectal cancer_Homo sapiens_hsa052101.42938910
11Renal cell carcinoma_Homo sapiens_hsa052111.31129094
12Glioma_Homo sapiens_hsa052141.28530052
13T cell receptor signaling pathway_Homo sapiens_hsa046601.27691998
14Neurotrophin signaling pathway_Homo sapiens_hsa047221.24385274
15Type II diabetes mellitus_Homo sapiens_hsa049301.23408272
16Endometrial cancer_Homo sapiens_hsa052131.23400679
17B cell receptor signaling pathway_Homo sapiens_hsa046621.21209295
18Prostate cancer_Homo sapiens_hsa052151.19293056
19Phosphatidylinositol signaling system_Homo sapiens_hsa040701.18506041
20Wnt signaling pathway_Homo sapiens_hsa043101.17227040
21Non-small cell lung cancer_Homo sapiens_hsa052231.16063323
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15329742
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.14882434
24ErbB signaling pathway_Homo sapiens_hsa040121.13883828
25Notch signaling pathway_Homo sapiens_hsa043301.13534343
26Proteoglycans in cancer_Homo sapiens_hsa052051.13099430
27Basal cell carcinoma_Homo sapiens_hsa052171.08668748
28Pancreatic cancer_Homo sapiens_hsa052121.06853326
29Estrogen signaling pathway_Homo sapiens_hsa049151.06560211
30Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.03820872
31Dilated cardiomyopathy_Homo sapiens_hsa054141.03599652
32Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.03598508
33Renin secretion_Homo sapiens_hsa049241.03317909
34Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.02874888
35FoxO signaling pathway_Homo sapiens_hsa040681.02579444
36Longevity regulating pathway - mammal_Homo sapiens_hsa042111.01382174
37Hippo signaling pathway_Homo sapiens_hsa043901.00163449
38Viral myocarditis_Homo sapiens_hsa054160.99983272
39Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.99907903
40cGMP-PKG signaling pathway_Homo sapiens_hsa040220.99303907
41Choline metabolism in cancer_Homo sapiens_hsa052310.99181175
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98251189
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.98117463
44Circadian entrainment_Homo sapiens_hsa047130.97967856
45Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97295010
46TGF-beta signaling pathway_Homo sapiens_hsa043500.96742024
47MAPK signaling pathway_Homo sapiens_hsa040100.95828446
48Glutamatergic synapse_Homo sapiens_hsa047240.95744922
49Oocyte meiosis_Homo sapiens_hsa041140.95697398
50Insulin secretion_Homo sapiens_hsa049110.94608675
51Melanogenesis_Homo sapiens_hsa049160.93923681
52Long-term depression_Homo sapiens_hsa047300.93681269
53Glucagon signaling pathway_Homo sapiens_hsa049220.93592864
54Axon guidance_Homo sapiens_hsa043600.92060642
55Dopaminergic synapse_Homo sapiens_hsa047280.92052736
56Hepatitis B_Homo sapiens_hsa051610.91632562
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.91322479
58Spliceosome_Homo sapiens_hsa030400.90329828
59Acute myeloid leukemia_Homo sapiens_hsa052210.89971252
60Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.89443903
61Focal adhesion_Homo sapiens_hsa045100.89289981
62cAMP signaling pathway_Homo sapiens_hsa040240.88117041
63Melanoma_Homo sapiens_hsa052180.87761292
64Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.87692577
65Insulin resistance_Homo sapiens_hsa049310.87560550
66Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.87545704
67Hedgehog signaling pathway_Homo sapiens_hsa043400.87138392
68Cell cycle_Homo sapiens_hsa041100.86739709
69Olfactory transduction_Homo sapiens_hsa047400.86193012
70Primary immunodeficiency_Homo sapiens_hsa053400.85846740
71Viral carcinogenesis_Homo sapiens_hsa052030.85750158
72Rap1 signaling pathway_Homo sapiens_hsa040150.85047036
73RNA transport_Homo sapiens_hsa030130.84720276
74Oxytocin signaling pathway_Homo sapiens_hsa049210.84633730
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.84550466
76HTLV-I infection_Homo sapiens_hsa051660.84283584
77Central carbon metabolism in cancer_Homo sapiens_hsa052300.84071585
78Cholinergic synapse_Homo sapiens_hsa047250.83997210
79Morphine addiction_Homo sapiens_hsa050320.82084106
80Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81938791
81Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81704777
82Pathways in cancer_Homo sapiens_hsa052000.81387563
83GnRH signaling pathway_Homo sapiens_hsa049120.81297329
84Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.80883094
85Insulin signaling pathway_Homo sapiens_hsa049100.80645749
86Salivary secretion_Homo sapiens_hsa049700.80232793
87Platelet activation_Homo sapiens_hsa046110.78825653
88Amphetamine addiction_Homo sapiens_hsa050310.78727547
89Thyroid hormone synthesis_Homo sapiens_hsa049180.78561884
90AMPK signaling pathway_Homo sapiens_hsa041520.78300411
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78271122
92Small cell lung cancer_Homo sapiens_hsa052220.78125261
93Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.77890081
94Inositol phosphate metabolism_Homo sapiens_hsa005620.77815723
95Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77671279
96Nicotine addiction_Homo sapiens_hsa050330.77151418
97Gap junction_Homo sapiens_hsa045400.76823748
98Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.74842661
99Chemokine signaling pathway_Homo sapiens_hsa040620.74428169
100Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74383605
101Thyroid cancer_Homo sapiens_hsa052160.72898745
102Non-homologous end-joining_Homo sapiens_hsa034500.72514493
103Circadian rhythm_Homo sapiens_hsa047100.72432144
104Leukocyte transendothelial migration_Homo sapiens_hsa046700.71633797
105VEGF signaling pathway_Homo sapiens_hsa043700.71170124
106AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.70839385
107Cocaine addiction_Homo sapiens_hsa050300.70368275
108Gastric acid secretion_Homo sapiens_hsa049710.70326460
109Prolactin signaling pathway_Homo sapiens_hsa049170.66894898
110RNA degradation_Homo sapiens_hsa030180.65251265
111Tight junction_Homo sapiens_hsa045300.59759590
112Bladder cancer_Homo sapiens_hsa052190.55226667
113Basal transcription factors_Homo sapiens_hsa030220.53532558
114Ras signaling pathway_Homo sapiens_hsa040140.53153687
115DNA replication_Homo sapiens_hsa030300.52035643
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51524746
117Fanconi anemia pathway_Homo sapiens_hsa034600.50759137

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