RPRM

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.44134983
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.43086130
3layer formation in cerebral cortex (GO:0021819)5.28956546
4synaptic vesicle exocytosis (GO:0016079)5.25558845
5cell migration in hindbrain (GO:0021535)5.14534253
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.08772766
7protein localization to synapse (GO:0035418)5.05107664
8neuron cell-cell adhesion (GO:0007158)5.02989648
9glutamate secretion (GO:0014047)4.96916847
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.92810870
11regulation of synaptic vesicle exocytosis (GO:2000300)4.84765237
12locomotory exploration behavior (GO:0035641)4.83575172
13pyrimidine nucleobase catabolic process (GO:0006208)4.70476848
14vocalization behavior (GO:0071625)4.69623802
15negative regulation of microtubule polymerization (GO:0031115)4.64202332
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.50305481
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.48164823
18regulation of glutamate receptor signaling pathway (GO:1900449)4.43571447
19exploration behavior (GO:0035640)4.37252256
20proline transport (GO:0015824)4.32161490
21neuron recognition (GO:0008038)4.25854182
22neuronal action potential propagation (GO:0019227)4.18729881
23regulation of synapse structural plasticity (GO:0051823)4.17350558
24regulation of synaptic vesicle transport (GO:1902803)4.13913723
25axonal fasciculation (GO:0007413)4.13754036
26dendritic spine morphogenesis (GO:0060997)3.95065416
27nucleobase catabolic process (GO:0046113)3.93254428
28ionotropic glutamate receptor signaling pathway (GO:0035235)3.86336327
29dendrite morphogenesis (GO:0048813)3.85778205
30regulation of neuronal synaptic plasticity (GO:0048168)3.77642881
31neurotransmitter secretion (GO:0007269)3.73326283
32innervation (GO:0060384)3.65169285
33synaptic transmission, glutamatergic (GO:0035249)3.64180766
34regulation of long-term neuronal synaptic plasticity (GO:0048169)3.63763839
35postsynaptic membrane organization (GO:0001941)3.62812615
36axon extension (GO:0048675)3.54805573
37glutamate receptor signaling pathway (GO:0007215)3.52950666
38activation of protein kinase A activity (GO:0034199)3.52421819
39regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.49898732
40positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.38332547
41neuron-neuron synaptic transmission (GO:0007270)3.35951217
42central nervous system projection neuron axonogenesis (GO:0021952)3.34185039
43positive regulation of synapse maturation (GO:0090129)3.29041327
44regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.28248770
45neurotransmitter-gated ion channel clustering (GO:0072578)3.26930209
46mechanosensory behavior (GO:0007638)3.26902610
47histone arginine methylation (GO:0034969)3.25168305
48righting reflex (GO:0060013)3.24557058
49presynaptic membrane organization (GO:0097090)3.21068594
50neuromuscular process controlling balance (GO:0050885)3.20600788
51positive regulation of synaptic transmission, GABAergic (GO:0032230)3.18289031
52startle response (GO:0001964)3.18174545
53neuron projection extension (GO:1990138)3.17038470
54regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.16285689
55response to dietary excess (GO:0002021)3.16204073
56peptidyl-arginine omega-N-methylation (GO:0035247)3.15750307
57organelle transport along microtubule (GO:0072384)3.15372844
58regulation of neurotransmitter secretion (GO:0046928)3.14165824
59regulation of excitatory postsynaptic membrane potential (GO:0060079)3.12095407
60regulation of dendritic spine morphogenesis (GO:0061001)3.12095033
61gamma-aminobutyric acid transport (GO:0015812)3.11878447
62establishment of mitochondrion localization (GO:0051654)3.11820054
63synapse assembly (GO:0007416)3.11218712
64synaptic vesicle endocytosis (GO:0048488)3.10999347
65detection of temperature stimulus (GO:0016048)3.10956348
66regulation of vesicle fusion (GO:0031338)3.10707708
67cerebellar Purkinje cell differentiation (GO:0021702)3.07554216
68positive regulation of membrane potential (GO:0045838)3.07231549
69regulation of postsynaptic membrane potential (GO:0060078)3.06466304
70clathrin coat assembly (GO:0048268)3.05688684
71establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.05544576
72mitochondrion transport along microtubule (GO:0047497)3.05544576
73regulation of synaptic plasticity (GO:0048167)3.05360419
74transmission of nerve impulse (GO:0019226)3.02276708
75neurotransmitter transport (GO:0006836)3.00736261
76adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.98955646
77vesicle transport along microtubule (GO:0047496)2.98777665
78negative regulation of dendrite development (GO:2000171)2.97754682
79axon cargo transport (GO:0008088)2.94419666
80presynaptic membrane assembly (GO:0097105)2.94185808
81negative regulation of dendrite morphogenesis (GO:0050774)2.92978473
82hippocampus development (GO:0021766)2.90651079
83behavioral defense response (GO:0002209)2.89891106
84behavioral fear response (GO:0001662)2.89891106
85mesenchymal to epithelial transition (GO:0060231)2.89675444
86regulation of cAMP-dependent protein kinase activity (GO:2000479)2.89520752
87peptidyl-arginine N-methylation (GO:0035246)2.88047279
88peptidyl-arginine methylation (GO:0018216)2.88047279
89cell communication by electrical coupling (GO:0010644)2.88000251
90cerebellar granule cell differentiation (GO:0021707)2.87995475
91neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.87539867
92calcium-mediated signaling using intracellular calcium source (GO:0035584)2.87063528
93positive regulation of synapse assembly (GO:0051965)2.86102694
94positive regulation of neurotransmitter secretion (GO:0001956)2.86040362
95cerebellum development (GO:0021549)2.85249257
96mating behavior (GO:0007617)2.85064647
97synapse organization (GO:0050808)2.85051578
98membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.84918475
99long-term memory (GO:0007616)2.84766231
100regulation of respiratory system process (GO:0044065)2.83596156
101auditory behavior (GO:0031223)2.83095806
102cerebral cortex neuron differentiation (GO:0021895)2.82335833
103retinal ganglion cell axon guidance (GO:0031290)2.81323977
104G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.81107657
105neuromuscular process (GO:0050905)2.80575503
106protein insertion into membrane (GO:0051205)2.79702611
107regulation of synaptic transmission, glutamatergic (GO:0051966)2.78276248
108regulation of voltage-gated calcium channel activity (GO:1901385)2.78053113
109detection of temperature stimulus involved in sensory perception (GO:0050961)2.76653872
110detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.76653872
111positive regulation of dendritic spine development (GO:0060999)2.75755359
112response to auditory stimulus (GO:0010996)2.75724324
113negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.75388975
114dopamine receptor signaling pathway (GO:0007212)2.75028664
115membrane depolarization (GO:0051899)2.74944519
116dendrite development (GO:0016358)2.74889586
117positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.69863080
118G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.66953479
119regulation of synapse assembly (GO:0051963)2.60588481
120cranial nerve morphogenesis (GO:0021602)2.60214004
121dendritic spine organization (GO:0097061)2.57450525
122adult walking behavior (GO:0007628)2.51904415
123regulation of synapse organization (GO:0050807)2.47370067
124cellular potassium ion homeostasis (GO:0030007)2.44994281
125cerebellar Purkinje cell layer development (GO:0021680)2.43195468
126positive regulation of dendritic spine morphogenesis (GO:0061003)2.42392884
127neurofilament cytoskeleton organization (GO:0060052)2.41064212
128dorsal/ventral neural tube patterning (GO:0021904)2.36227209
129epithelial cell differentiation involved in kidney development (GO:0035850)2.31380869
130regulation of synapse maturation (GO:0090128)2.30511354
131skeletal muscle organ development (GO:0060538)2.29094615
132neuron projection regeneration (GO:0031102)2.27668367
133respiratory system process (GO:0003016)2.24965746
134regulation of neurotransmitter levels (GO:0001505)2.24694016
135nervous system development (GO:0007399)2.24139858

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.36444360
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.37961510
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.26653101
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.21110466
5GBX2_23144817_ChIP-Seq_PC3_Human3.12579936
6* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.06733548
7JARID2_20075857_ChIP-Seq_MESCs_Mouse3.03791889
8EZH2_18974828_ChIP-Seq_MESCs_Mouse3.03206645
9RNF2_18974828_ChIP-Seq_MESCs_Mouse3.03206645
10EZH2_27304074_Chip-Seq_ESCs_Mouse3.01273413
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.96752186
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.73985404
13* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.71497980
14REST_21632747_ChIP-Seq_MESCs_Mouse2.68203316
15* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.63912710
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58030059
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.53242796
18* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.50390170
19* EZH2_27294783_Chip-Seq_ESCs_Mouse2.49718873
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.48315602
21TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.40290848
22RNF2_27304074_Chip-Seq_ESCs_Mouse2.36364647
23CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.22034198
24* REST_18959480_ChIP-ChIP_MESCs_Mouse2.21571793
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.14202802
26DROSHA_22980978_ChIP-Seq_HELA_Human2.06269316
27AR_21572438_ChIP-Seq_LNCaP_Human1.99027293
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94753441
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.90276389
30GATA1_26923725_Chip-Seq_HPCs_Mouse1.88974406
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.84505953
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.83019989
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.80107471
34EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79208949
35HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.78726156
36* TAF15_26573619_Chip-Seq_HEK293_Human1.77780669
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.74685078
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.72042571
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71331582
40* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.70663334
41KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.68167442
42KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.68167442
43KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.68167442
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.66500432
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.65889863
46RING1B_27294783_Chip-Seq_ESCs_Mouse1.57863593
47ZNF274_21170338_ChIP-Seq_K562_Hela1.56492373
48* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.48313096
49* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.47204688
50NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.45351348
51RNF2_27304074_Chip-Seq_NSC_Mouse1.44667007
52ESR1_15608294_ChIP-ChIP_MCF-7_Human1.44550460
53* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42111316
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41178246
55SMAD4_21799915_ChIP-Seq_A2780_Human1.40885991
56MYC_18555785_ChIP-Seq_MESCs_Mouse1.40385177
57* RING1B_27294783_Chip-Seq_NPCs_Mouse1.36897926
58KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.36816820
59* P300_19829295_ChIP-Seq_ESCs_Human1.35349487
60NR3C1_23031785_ChIP-Seq_PC12_Mouse1.34495399
61SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.33947592
62POU5F1_16153702_ChIP-ChIP_HESCs_Human1.29509731
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.28612641
64XRN2_22483619_ChIP-Seq_HELA_Human1.28487984
65* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28387640
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.25493913
67POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.23978400
68* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.23178708
69RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.22665038
70WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22162750
71FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.19243746
72* SOX2_21211035_ChIP-Seq_LN229_Gbm1.19165011
73TP53_20018659_ChIP-ChIP_R1E_Mouse1.18540411
74KDM2B_26808549_Chip-Seq_K562_Human1.18285047
75* SOX2_16153702_ChIP-ChIP_HESCs_Human1.18044571
76* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17813505
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16321442
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15873487
79* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.14790818
80SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.14525037
81AR_25329375_ChIP-Seq_VCAP_Human1.12783306
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12171882
83* SMAD3_21741376_ChIP-Seq_EPCs_Human1.12166166
84ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.09471539
85P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09404701
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08234669
87SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.07905413
88* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07199417
89* ARNT_22903824_ChIP-Seq_MCF-7_Human1.05227984
90* AR_19668381_ChIP-Seq_PC3_Human1.04378383
91IGF1R_20145208_ChIP-Seq_DFB_Human1.04375251
92PIAS1_25552417_ChIP-Seq_VCAP_Human1.04151749
93TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.02637688
94* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.02427918
95* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02085261
96SOX3_22085726_ChIP-Seq_NPCs_Mouse1.00809132
97SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00423031
98* AHR_22903824_ChIP-Seq_MCF-7_Human1.00338751
99YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00146786
100E2F7_22180533_ChIP-Seq_HELA_Human0.99964825
101ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.99516416
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99111619
103EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.99011553
104MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.98428960
105* SMAD3_21741376_ChIP-Seq_ESCs_Human0.98161188
106CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97711121
107CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.97128981
108NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.96214364
109POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95745102
110PRDM14_20953172_ChIP-Seq_ESCs_Human0.94625700
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94497675
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94497675
113SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.93494899
114* CTCF_27219007_Chip-Seq_Bcells_Human0.92615786
115MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92386570
116ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91730648
117STAT3_23295773_ChIP-Seq_U87_Human0.90804394
118SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.90513306
119CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89603750
120TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.89506063
121TET1_21451524_ChIP-Seq_MESCs_Mouse0.89357818
122* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.89112389
123TP53_18474530_ChIP-ChIP_U2OS_Human0.88369148
124* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.88109002
125* ZNF217_24962896_ChIP-Seq_MCF-7_Human0.87617278
126* RUNX2_22187159_ChIP-Seq_PCA_Human0.87237692
127SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87093076
128TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86955215
129MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.86876011
130RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.86517121
131SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.86426088
132* JUN_21703547_ChIP-Seq_K562_Human0.85897557
133RUNX1_26923725_Chip-Seq_HPCs_Mouse0.85798552
134TET1_21490601_ChIP-Seq_MESCs_Mouse0.85237637
135* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.83750219
136MYC_19079543_ChIP-ChIP_MESCs_Mouse0.83349649
137CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.83319923
138* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.82438899
139ELK4_26923725_Chip-Seq_MESODERM_Mouse0.82311660
140POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.82299940
141* SMAD4_21741376_ChIP-Seq_HESCs_Human0.81544874
142* TTF2_22483619_ChIP-Seq_HELA_Human0.81343819
143AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.81090996
144POU5F1_16518401_ChIP-PET_MESCs_Mouse0.81060026
145BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.80063075
146HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.79276328

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.79121582
2MP0003880_abnormal_central_pattern4.52498960
3MP0004270_analgesia4.06789505
4MP0003635_abnormal_synaptic_transmissio3.67997009
5MP0001968_abnormal_touch/_nociception3.48331560
6MP0002735_abnormal_chemical_nociception3.09211367
7MP0002063_abnormal_learning/memory/cond3.02900478
8MP0002734_abnormal_mechanical_nocicepti2.93331018
9MP0002736_abnormal_nociception_after2.89444814
10MP0009745_abnormal_behavioral_response2.76758832
11MP0004858_abnormal_nervous_system2.75056040
12MP0000778_abnormal_nervous_system2.70950601
13MP0002733_abnormal_thermal_nociception2.69384388
14MP0005423_abnormal_somatic_nervous2.68472523
15MP0006276_abnormal_autonomic_nervous2.65416793
16MP0002064_seizures2.63741519
17MP0002572_abnormal_emotion/affect_behav2.49872650
18MP0002184_abnormal_innervation2.38287487
19MP0001970_abnormal_pain_threshold2.36591130
20MP0001440_abnormal_grooming_behavior2.24871464
21MP0009046_muscle_twitch2.20829487
22MP0001486_abnormal_startle_reflex2.12143782
23MP0002272_abnormal_nervous_system2.08054498
24MP0004811_abnormal_neuron_physiology1.99500939
25MP0002067_abnormal_sensory_capabilities1.90554055
26MP0004133_heterotaxia1.84445975
27MP0000955_abnormal_spinal_cord1.80827246
28MP0002557_abnormal_social/conspecific_i1.79133168
29MP0000049_abnormal_middle_ear1.77385907
30MP0003329_amyloid_beta_deposits1.76227914
31MP0001984_abnormal_olfaction1.73717081
32MP0003879_abnormal_hair_cell1.63510519
33MP0009780_abnormal_chondrocyte_physiolo1.62480537
34MP0005645_abnormal_hypothalamus_physiol1.62368969
35MP0002882_abnormal_neuron_morphology1.61571520
36MP0004924_abnormal_behavior1.61203171
37MP0005386_behavior/neurological_phenoty1.61203171
38MP0001501_abnormal_sleep_pattern1.59627157
39MP0003122_maternal_imprinting1.55654087
40MP0002249_abnormal_larynx_morphology1.48750130
41MP0005499_abnormal_olfactory_system1.45030241
42MP0005394_taste/olfaction_phenotype1.45030241
43MP0008569_lethality_at_weaning1.39912214
44MP0003136_yellow_coat_color1.39849210
45MP0002066_abnormal_motor_capabilities/c1.34110266
46MP0002152_abnormal_brain_morphology1.31110834
47MP0002909_abnormal_adrenal_gland1.29717069
48MP0003787_abnormal_imprinting1.29509239
49MP0003937_abnormal_limbs/digits/tail_de1.26842720
50MP0003123_paternal_imprinting1.22467748
51MP0000751_myopathy1.20514485
52MP0004885_abnormal_endolymph1.20243220
53MP0004742_abnormal_vestibular_system1.18983884
54MP0006292_abnormal_olfactory_placode1.16722871
55MP0003890_abnormal_embryonic-extraembry1.16666265
56MP0000579_abnormal_nail_morphology1.14721128
57MP0002234_abnormal_pharynx_morphology1.14570620
58MP0010030_abnormal_orbit_morphology1.13938984
59MP0008789_abnormal_olfactory_epithelium1.13608714
60MP0001502_abnormal_circadian_rhythm1.13603054
61MP0002751_abnormal_autonomic_nervous1.13211644
62MP0001346_abnormal_lacrimal_gland1.12266176
63MP0004142_abnormal_muscle_tone1.12062683
64MP0005646_abnormal_pituitary_gland1.09153473
65MP0002752_abnormal_somatic_nervous1.08407325
66MP0001529_abnormal_vocalization1.07920999
67MP0002697_abnormal_eye_size1.07823776
68MP0000631_abnormal_neuroendocrine_gland1.07255352
69MP0000569_abnormal_digit_pigmentation1.07153978
70MP0002822_catalepsy1.06510900
71MP0003567_abnormal_fetal_cardiomyocyte1.06099000
72MP0001348_abnormal_lacrimal_gland1.02195541
73MP0005623_abnormal_meninges_morphology1.00565438
74MP0001905_abnormal_dopamine_level0.99600826
75MP0003861_abnormal_nervous_system0.99508988
76MP0003385_abnormal_body_wall0.95191013
77MP0005187_abnormal_penis_morphology0.93678336
78MP0008877_abnormal_DNA_methylation0.93313907
79MP0001963_abnormal_hearing_physiology0.90557319
80MP0008932_abnormal_embryonic_tissue0.90095519
81MP0002069_abnormal_eating/drinking_beha0.90032254
82MP0003634_abnormal_glial_cell0.88856649
83MP0002653_abnormal_ependyma_morphology0.88404994
84MP0003693_abnormal_embryo_hatching0.88032667
85MP0001286_abnormal_eye_development0.86230138
86MP0001293_anophthalmia0.84877362
87MP0000537_abnormal_urethra_morphology0.84816730
88MP0002229_neurodegeneration0.82035258
89MP0001188_hyperpigmentation0.81873179
90MP0000534_abnormal_ureter_morphology0.81357494
91MP0003633_abnormal_nervous_system0.80999325
92MP0009250_abnormal_appendicular_skeleto0.80408621
93MP0003137_abnormal_impulse_conducting0.78944671
94MP0009672_abnormal_birth_weight0.76931568
95MP0008961_abnormal_basal_metabolism0.75948661
96MP0000026_abnormal_inner_ear0.75846611
97MP0002233_abnormal_nose_morphology0.75460171
98MP0003631_nervous_system_phenotype0.75131571
99MP0002837_dystrophic_cardiac_calcinosis0.75097513
100MP0001664_abnormal_digestion0.74446202
101MP0001485_abnormal_pinna_reflex0.74217865
102MP0005367_renal/urinary_system_phenotyp0.74180590
103MP0000516_abnormal_urinary_system0.74180590
104MP0010386_abnormal_urinary_bladder0.73982143
105MP0010768_mortality/aging0.73290816
106MP0003942_abnormal_urinary_system0.71843440
107MP0004085_abnormal_heartbeat0.70700732
108MP0000604_amyloidosis0.70423806
109MP0009379_abnormal_foot_pigmentation0.67083104
110MP0001299_abnormal_eye_distance/0.65796434
111MP0003283_abnormal_digestive_organ0.65454746
112MP0001943_abnormal_respiration0.64431836
113MP0002102_abnormal_ear_morphology0.63066291
114MP0002638_abnormal_pupillary_reflex0.62541143
115MP0003938_abnormal_ear_development0.61990327
116MP0003121_genomic_imprinting0.60963522
117MP0006072_abnormal_retinal_apoptosis0.60422027
118MP0001177_atelectasis0.58838657
119MP0008874_decreased_physiological_sensi0.58394780
120MP0005551_abnormal_eye_electrophysiolog0.57732586
121MP0002081_perinatal_lethality0.56070841
122MP0008872_abnormal_physiological_respon0.54969705
123MP0010769_abnormal_survival0.54759709
124MP0002082_postnatal_lethality0.54699185
125MP0010770_preweaning_lethality0.54699185
126MP0004145_abnormal_muscle_electrophysio0.53753683
127MP0003119_abnormal_digestive_system0.52460020

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.41040818
2Focal motor seizures (HP:0011153)5.58958448
3Focal seizures (HP:0007359)4.70626379
4Visual hallucinations (HP:0002367)4.46194917
5Epileptic encephalopathy (HP:0200134)3.90909978
6Supranuclear gaze palsy (HP:0000605)3.83600185
7Progressive cerebellar ataxia (HP:0002073)3.71529656
8Atonic seizures (HP:0010819)3.68748177
9Ankle clonus (HP:0011448)3.45594188
10Febrile seizures (HP:0002373)3.38846504
11Action tremor (HP:0002345)3.34542768
12Absence seizures (HP:0002121)3.32925439
13Mutism (HP:0002300)3.29326390
14Amblyopia (HP:0000646)3.25893334
15Generalized tonic-clonic seizures (HP:0002069)3.07088465
16Limb dystonia (HP:0002451)3.05530581
17Termporal pattern (HP:0011008)3.03206532
18Insidious onset (HP:0003587)3.03206532
19Dialeptic seizures (HP:0011146)3.01025083
20Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.99504145
21Papilledema (HP:0001085)2.93521225
22Polyphagia (HP:0002591)2.87703070
23Depression (HP:0000716)2.84868943
24Broad-based gait (HP:0002136)2.84341930
25Hypoplasia of the brainstem (HP:0002365)2.82031805
26Aplasia/Hypoplasia of the brainstem (HP:0007362)2.82031805
27Impaired vibration sensation in the lower limbs (HP:0002166)2.80493250
28Congenital malformation of the right heart (HP:0011723)2.77145181
29Double outlet right ventricle (HP:0001719)2.77145181
30Abnormality of the lower motor neuron (HP:0002366)2.69466145
31Pheochromocytoma (HP:0002666)2.69067367
32Urinary urgency (HP:0000012)2.68167934
33Abnormal eating behavior (HP:0100738)2.66971380
34Abnormality of the corticospinal tract (HP:0002492)2.66561318
35Urinary bladder sphincter dysfunction (HP:0002839)2.66035512
36Failure to thrive in infancy (HP:0001531)2.63019442
37Cortical dysplasia (HP:0002539)2.59650833
38Amyotrophic lateral sclerosis (HP:0007354)2.58075603
39Anxiety (HP:0000739)2.57942810
40Hyperventilation (HP:0002883)2.57113300
41Excessive salivation (HP:0003781)2.56769293
42Drooling (HP:0002307)2.56769293
43Truncal ataxia (HP:0002078)2.56572569
44Akinesia (HP:0002304)2.55581869
45Abnormal ventriculo-arterial connection (HP:0011563)2.52106102
46Transposition of the great arteries (HP:0001669)2.52106102
47Abnormal connection of the cardiac segments (HP:0011545)2.52106102
48Cerebral inclusion bodies (HP:0100314)2.51304636
49Agitation (HP:0000713)2.51150889
50Colon cancer (HP:0003003)2.47852521
51Abnormality of the aortic arch (HP:0012303)2.44386530
52Megalencephaly (HP:0001355)2.44290488
53Poor eye contact (HP:0000817)2.40977806
54Progressive inability to walk (HP:0002505)2.34972479
55Neuroendocrine neoplasm (HP:0100634)2.32215200
56Insomnia (HP:0100785)2.31945524
57Spastic gait (HP:0002064)2.30243410
58Neurofibrillary tangles (HP:0002185)2.29019949
59Ulnar claw (HP:0001178)2.26635965
60Fetal akinesia sequence (HP:0001989)2.26135069
61Septo-optic dysplasia (HP:0100842)2.25969797
62Torticollis (HP:0000473)2.24365502
63Focal dystonia (HP:0004373)2.22920675
64Epileptiform EEG discharges (HP:0011182)2.21800064
65Abnormality of binocular vision (HP:0011514)2.21548076
66Diplopia (HP:0000651)2.21548076
67Periauricular skin pits (HP:0100277)2.18835827
68Preauricular pit (HP:0004467)2.18835827
69Hypoventilation (HP:0002791)2.18286316
70Myotonia (HP:0002486)2.18165418
71Hypoplastic left heart (HP:0004383)2.17941996
72Hemiparesis (HP:0001269)2.17851163
73EEG with generalized epileptiform discharges (HP:0011198)2.17478493
74Sleep apnea (HP:0010535)2.16635551
75Apathy (HP:0000741)2.15016852
76High anterior hairline (HP:0009890)2.13317612
77Genetic anticipation (HP:0003743)2.11730495
78Specific learning disability (HP:0001328)2.11366017
79Gaze-evoked nystagmus (HP:0000640)2.09249076
80Obstructive sleep apnea (HP:0002870)2.08425073
81Hypsarrhythmia (HP:0002521)2.08249142
82Impaired social interactions (HP:0000735)2.06504285
83Abnormal social behavior (HP:0012433)2.06504285
84Neoplasm of the peripheral nervous system (HP:0100007)2.06358399
85Inability to walk (HP:0002540)2.06117560
86Gait imbalance (HP:0002141)2.05949125
87Broad distal phalanx of finger (HP:0009836)2.05734243
88Split foot (HP:0001839)2.05583162
89Delusions (HP:0000746)2.04426206
90Hyperthyroidism (HP:0000836)2.03837473
91Craniofacial dystonia (HP:0012179)2.03735245
92Lissencephaly (HP:0001339)2.03387080
93Lower limb muscle weakness (HP:0007340)2.02934031
94Exotropia (HP:0000577)1.98895588
95Generalized hypotonia (HP:0001290)1.97528169
96Cutaneous syndactyly (HP:0012725)1.97474214
97Cerebral hypomyelination (HP:0006808)1.96109495
98Cutaneous finger syndactyly (HP:0010554)1.95385643
99Restlessness (HP:0000711)1.95020325
100Shoulder girdle muscle weakness (HP:0003547)1.94195064
101Dysmetria (HP:0001310)1.93594356
102Morphological abnormality of the pyramidal tract (HP:0002062)1.93343030
103Diminished motivation (HP:0000745)1.92804209
104Bradykinesia (HP:0002067)1.92544580
105Impaired pain sensation (HP:0007328)1.91340305
106Abnormality of pain sensation (HP:0010832)1.91340305
107Peripheral hypomyelination (HP:0007182)1.89736972
108Stereotypic behavior (HP:0000733)1.89223369
109Absent speech (HP:0001344)1.89199198
110Atrophy/Degeneration involving motor neurons (HP:0007373)1.89026325
111Truncus arteriosus (HP:0001660)1.87486316
112Hepatoblastoma (HP:0002884)1.87394102
113Oligodactyly (HP:0012165)1.84286116
114Diminished movement (HP:0002374)1.84148029
115Oligodactyly (hands) (HP:0001180)1.82997041
116Pachygyria (HP:0001302)1.82576443
117Hypercortisolism (HP:0001578)1.82435475
118Inappropriate behavior (HP:0000719)1.82040498
119Poor suck (HP:0002033)1.81789581
120Dysdiadochokinesis (HP:0002075)1.80691011
121Retinal dysplasia (HP:0007973)1.79964331
122Unilateral renal agenesis (HP:0000122)1.79952709
123Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.79708752
124Pointed chin (HP:0000307)1.79107534
125Anophthalmia (HP:0000528)1.79063416
126Sporadic (HP:0003745)1.78428227
127Turricephaly (HP:0000262)1.77412100
128Abnormality of the labia minora (HP:0012880)1.77110680
129Rapidly progressive (HP:0003678)1.76656927
130Abnormality of abdominal situs (HP:0011620)1.76127357
131Abdominal situs inversus (HP:0003363)1.76127357
132Cerebellar dysplasia (HP:0007033)1.75752522
133Aplasia/Hypoplasia of the sacrum (HP:0008517)1.75433210
134Hypoplastic heart (HP:0001961)1.74597250
135Maternal diabetes (HP:0009800)1.71737075
136Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.70337876
137Degeneration of the lateral corticospinal tracts (HP:0002314)1.70337876
138Myelomeningocele (HP:0002475)1.64351064
139Absent septum pellucidum (HP:0001331)1.63063180
140Astrocytoma (HP:0009592)1.62930266
141Abnormality of the astrocytes (HP:0100707)1.62930266
142Rib fusion (HP:0000902)1.61501173
143Renal dysplasia (HP:0000110)1.60709497
144Abnormality of cochlea (HP:0000375)1.59146708
145Down-sloping shoulders (HP:0200021)1.58547498
146Optic nerve coloboma (HP:0000588)1.58278699
147Sclerocornea (HP:0000647)1.57825490
148Mixed hearing impairment (HP:0000410)1.57406139
149Polymicrogyria (HP:0002126)1.55353032
150Esotropia (HP:0000565)1.53426587
151Type II lissencephaly (HP:0007260)1.52048325

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.30495522
2NTRK33.73113278
3MAP3K93.72163943
4MAP3K43.14099486
5MINK12.99648025
6MAP2K72.69191624
7EPHA42.40459309
8MAPK132.40438161
9DAPK22.40252202
10TAF12.28817673
11NTRK22.12746410
12PAK62.12148551
13MAP3K122.07752663
14CASK2.07615189
15KSR21.99590271
16LATS21.97463320
17VRK21.94727815
18MAP2K41.92574242
19SMG11.90958737
20PHKG11.85607861
21PHKG21.85607861
22GRK51.85034601
23KSR11.69603503
24NTRK11.69159112
25ARAF1.63549306
26PLK21.62141270
27LIMK11.57331467
28DYRK21.50556145
29SIK21.49173674
30UHMK11.47871622
31CDK51.47375631
32DAPK11.44275076
33CAMKK11.39062227
34PNCK1.23694816
35MAP3K21.17604486
36BRSK11.16779393
37CDK191.13655313
38RET1.12919727
39CDK141.11876035
40ERBB31.11280774
41CSNK1G21.06077228
42PRKCG1.05917288
43CDK181.05724527
44ICK1.05629422
45CDK151.01307701
46TLK11.00722514
47RIPK40.97861041
48CHEK20.95249073
49PTK2B0.93766215
50LMTK20.90846631
51TNIK0.89610798
52CDK11A0.89364892
53PAK30.88243594
54AURKA0.87520214
55EPHB20.86169653
56CAMKK20.85165961
57TYRO30.85042307
58TAOK10.82296742
59NME10.81627683
60ZAK0.80254568
61CAMK2A0.79820767
62PRKD30.79795433
63TRIM280.78942555
64RPS6KA20.78778852
65MARK20.78203780
66CAMK1D0.77947369
67DYRK1A0.76780529
68CDC70.74645406
69MAP3K100.74447171
70MAP3K110.72724630
71EEF2K0.72309403
72CSNK1G30.70507432
73TESK10.66478252
74MAP3K60.65471257
75BCR0.65442192
76PRKCZ0.60619882
77FER0.59426483
78RAF10.59206154
79CSNK1E0.58223428
80MAP2K10.58106173
81PBK0.57967594
82SGK2230.57642310
83SGK4940.57642310
84FES0.56263120
85SRPK10.55845250
86PRPF4B0.54941681
87CAMK2B0.54582632
88PDK20.53847872
89CCNB10.53302224
90STK110.53181354
91STK160.51685710
92VRK10.50833383
93DDR20.50348718
94CSNK1A1L0.50126679
95AKT20.50110225
96STK380.48465388
97SIK30.48404880
98DYRK30.46291333
99CAMK10.45813384
100DAPK30.45511296
101FGR0.45435000
102CSNK1D0.44363868
103ATR0.43077075
104ADRBK10.42790257
105ALK0.41429925
106PRKDC0.40090361
107MAP2K20.39864013
108EIF2AK20.39765127
109MAPK120.39594997
110PRKCE0.38355418
111CSNK1G10.36524564
112PRKCH0.36203107
113PRKAA10.35765970
114SCYL20.35740938
115CDK10.35155910
116BMPR20.35059581
117BRAF0.34964682
118CDK20.34708904
119PLK10.34557289
120FYN0.34403562
121OXSR10.34181343
122GSK3B0.33850081
123MAP3K10.33639114
124RPS6KA10.33530011
125CAMK1G0.33456309
126PKN10.33439201
127CAMK40.33179471
128NEK60.33071347
129ROCK20.32997056
130DYRK1B0.32860735
131MAPK100.32500710
132TESK20.31738687
133PRKCI0.30315051
134SGK20.29756576
135RPS6KA30.28297824
136MAPK90.28069329
137WNK30.27893680
138SGK10.27808266

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.44728426
2Nicotine addiction_Homo sapiens_hsa050333.15511955
3Olfactory transduction_Homo sapiens_hsa047402.69853580
4Circadian entrainment_Homo sapiens_hsa047132.35280423
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.34282940
6Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.32774060
7Long-term potentiation_Homo sapiens_hsa047202.27382130
8Glutamatergic synapse_Homo sapiens_hsa047242.24943525
9GABAergic synapse_Homo sapiens_hsa047272.23654331
10Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.14203181
11Dopaminergic synapse_Homo sapiens_hsa047282.13775769
12Morphine addiction_Homo sapiens_hsa050322.12581949
13Amphetamine addiction_Homo sapiens_hsa050312.02983415
14Vitamin B6 metabolism_Homo sapiens_hsa007501.92266243
15Cholinergic synapse_Homo sapiens_hsa047251.86888584
16Taste transduction_Homo sapiens_hsa047421.81775070
17Serotonergic synapse_Homo sapiens_hsa047261.76476123
18Insulin secretion_Homo sapiens_hsa049111.75877074
19Salivary secretion_Homo sapiens_hsa049701.74978514
20Collecting duct acid secretion_Homo sapiens_hsa049661.73737330
21Sulfur relay system_Homo sapiens_hsa041221.70495622
22Basal cell carcinoma_Homo sapiens_hsa052171.70027184
23Axon guidance_Homo sapiens_hsa043601.69400788
24Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.64409509
25Gastric acid secretion_Homo sapiens_hsa049711.60984056
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.58692425
27Gap junction_Homo sapiens_hsa045401.56980981
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.53024999
29DNA replication_Homo sapiens_hsa030301.51467968
30Oxytocin signaling pathway_Homo sapiens_hsa049211.49184366
31Long-term depression_Homo sapiens_hsa047301.48818350
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48642136
33Renin secretion_Homo sapiens_hsa049241.45558762
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.43863780
35GnRH signaling pathway_Homo sapiens_hsa049121.40790573
36Cocaine addiction_Homo sapiens_hsa050301.37445607
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.36547340
38Glioma_Homo sapiens_hsa052141.36433434
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.28611783
40Calcium signaling pathway_Homo sapiens_hsa040201.26851952
41Cardiac muscle contraction_Homo sapiens_hsa042601.24194145
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.22910074
43Vibrio cholerae infection_Homo sapiens_hsa051101.21337064
44Melanogenesis_Homo sapiens_hsa049161.21308790
45ErbB signaling pathway_Homo sapiens_hsa040121.21286046
46Estrogen signaling pathway_Homo sapiens_hsa049151.18241972
47Type II diabetes mellitus_Homo sapiens_hsa049301.08415894
48Mismatch repair_Homo sapiens_hsa034301.08275505
49Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07875478
50Oocyte meiosis_Homo sapiens_hsa041141.03964541
51Oxidative phosphorylation_Homo sapiens_hsa001901.02923894
52Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.01835115
53Steroid biosynthesis_Homo sapiens_hsa001001.01587105
54cAMP signaling pathway_Homo sapiens_hsa040240.99648823
55Parkinsons disease_Homo sapiens_hsa050120.97084656
56Alzheimers disease_Homo sapiens_hsa050100.95413203
57Ribosome_Homo sapiens_hsa030100.94846354
58VEGF signaling pathway_Homo sapiens_hsa043700.92382701
59Endometrial cancer_Homo sapiens_hsa052130.91452231
60Neurotrophin signaling pathway_Homo sapiens_hsa047220.91274616
61mRNA surveillance pathway_Homo sapiens_hsa030150.91179942
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.90975305
63cGMP-PKG signaling pathway_Homo sapiens_hsa040220.87906561
64Colorectal cancer_Homo sapiens_hsa052100.87886369
65Dorso-ventral axis formation_Homo sapiens_hsa043200.83922021
66Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.83265498
67Phototransduction_Homo sapiens_hsa047440.82439450
68Cell cycle_Homo sapiens_hsa041100.78259864
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78258126
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78167318
71Pancreatic secretion_Homo sapiens_hsa049720.77677614
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.77353715
73Spliceosome_Homo sapiens_hsa030400.77250459
74Biosynthesis of amino acids_Homo sapiens_hsa012300.76757748
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.76495230
76Base excision repair_Homo sapiens_hsa034100.75866988
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74261817
78Notch signaling pathway_Homo sapiens_hsa043300.73398200
79AMPK signaling pathway_Homo sapiens_hsa041520.72850255
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.71239907
81Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71178205
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.70491744
83Vascular smooth muscle contraction_Homo sapiens_hsa042700.70474711
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70073173
85MAPK signaling pathway_Homo sapiens_hsa040100.69732289
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68287761
87Ras signaling pathway_Homo sapiens_hsa040140.68042631
88Prion diseases_Homo sapiens_hsa050200.67912275
89Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.67660700
90Renal cell carcinoma_Homo sapiens_hsa052110.67513307
91Insulin signaling pathway_Homo sapiens_hsa049100.66999230
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66850460
93Wnt signaling pathway_Homo sapiens_hsa043100.66382317
94Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65897530
95RNA polymerase_Homo sapiens_hsa030200.65570342
96Huntingtons disease_Homo sapiens_hsa050160.65539911
97Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.64189494
98Choline metabolism in cancer_Homo sapiens_hsa052310.62878616
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.61591688
100Dilated cardiomyopathy_Homo sapiens_hsa054140.61336009
101Rap1 signaling pathway_Homo sapiens_hsa040150.59733143
1022-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59614290
103Alcoholism_Homo sapiens_hsa050340.59302001
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58871305
105Non-small cell lung cancer_Homo sapiens_hsa052230.58822406
106Thyroid hormone synthesis_Homo sapiens_hsa049180.57839167
107Cyanoamino acid metabolism_Homo sapiens_hsa004600.56146077
108RNA transport_Homo sapiens_hsa030130.55886593
109Endocytosis_Homo sapiens_hsa041440.55584723
110Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55110196
111Melanoma_Homo sapiens_hsa052180.54260234
112Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.53529207
113TGF-beta signaling pathway_Homo sapiens_hsa043500.53133222
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52734267
115Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.52311430
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51672028
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.50410943
118mTOR signaling pathway_Homo sapiens_hsa041500.48529537
119Hedgehog signaling pathway_Homo sapiens_hsa043400.48358674
120Tight junction_Homo sapiens_hsa045300.48294458
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.47359875
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45751389
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.44666807
124Hippo signaling pathway_Homo sapiens_hsa043900.43558228
125Glucagon signaling pathway_Homo sapiens_hsa049220.42472877
126Renin-angiotensin system_Homo sapiens_hsa046140.41933291
127Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.40065111
128Prolactin signaling pathway_Homo sapiens_hsa049170.39794331
129Phagosome_Homo sapiens_hsa041450.39226240
130Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.36782632
131Ovarian steroidogenesis_Homo sapiens_hsa049130.31851254
132Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30804594

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »