RPRML

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)6.71496376
2axon ensheathment in central nervous system (GO:0032291)6.71496376
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.85267918
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.76994106
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.63525871
6synaptic vesicle exocytosis (GO:0016079)5.60647079
7vocalization behavior (GO:0071625)5.60187936
8neuronal ion channel clustering (GO:0045161)5.47258208
9protein localization to synapse (GO:0035418)5.25961648
10glutamate secretion (GO:0014047)5.23243711
11synaptic vesicle maturation (GO:0016188)5.21598834
12locomotory exploration behavior (GO:0035641)5.19101956
13ionotropic glutamate receptor signaling pathway (GO:0035235)5.18522438
14regulation of glutamate receptor signaling pathway (GO:1900449)5.13890901
15positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.92133225
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.88624805
17regulation of synaptic vesicle exocytosis (GO:2000300)4.84720224
18glutamate receptor signaling pathway (GO:0007215)4.79510617
19neuronal action potential propagation (GO:0019227)4.79223357
20regulation of long-term neuronal synaptic plasticity (GO:0048169)4.77542510
21regulation of neuronal synaptic plasticity (GO:0048168)4.63317390
22neuron cell-cell adhesion (GO:0007158)4.58141102
23exploration behavior (GO:0035640)4.54804370
24synaptic transmission, glutamatergic (GO:0035249)4.51990005
25regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.40993989
26neuron-neuron synaptic transmission (GO:0007270)4.39239981
27regulation of synaptic vesicle transport (GO:1902803)4.39166999
28sodium ion export (GO:0071436)4.30958757
29regulation of excitatory postsynaptic membrane potential (GO:0060079)4.25051245
30neurotransmitter-gated ion channel clustering (GO:0072578)4.18619810
31positive regulation of synapse maturation (GO:0090129)4.12173626
32pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.08090583
33positive regulation of neurotransmitter secretion (GO:0001956)4.07624093
34regulation of synaptic plasticity (GO:0048167)4.05450420
35regulation of dendritic spine morphogenesis (GO:0061001)4.03789256
36long-term synaptic potentiation (GO:0060291)4.03309994
37regulation of postsynaptic membrane potential (GO:0060078)3.98674069
38neurotransmitter secretion (GO:0007269)3.98180647
39positive regulation of membrane potential (GO:0045838)3.95032200
40gamma-aminobutyric acid signaling pathway (GO:0007214)3.93610902
41long-term memory (GO:0007616)3.91507667
42dendritic spine morphogenesis (GO:0060997)3.90379965
43muscle cell fate commitment (GO:0042693)3.89690407
44regulation of synapse structural plasticity (GO:0051823)3.88203982
45regulation of glutamate secretion (GO:0014048)3.86010178
46neuron recognition (GO:0008038)3.85578068
47behavioral fear response (GO:0001662)3.84377153
48behavioral defense response (GO:0002209)3.84377153
49G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.82969077
50deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.79381771
51synaptic vesicle endocytosis (GO:0048488)3.76766557
52potassium ion import (GO:0010107)3.76460641
53pyrimidine nucleotide catabolic process (GO:0006244)3.73409349
54regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.73003736
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.72190412
56negative regulation of synaptic transmission, GABAergic (GO:0032229)3.71239639
57layer formation in cerebral cortex (GO:0021819)3.69517894
58pattern specification involved in kidney development (GO:0061004)3.67468538
59dendritic spine organization (GO:0097061)3.66161101
60positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.62421240
61fear response (GO:0042596)3.62075626
62response to histamine (GO:0034776)3.61025419
63positive regulation of neurotransmitter transport (GO:0051590)3.60821907
64presynaptic membrane assembly (GO:0097105)3.58980464
65postsynaptic membrane organization (GO:0001941)3.58056738
66G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.54033582
67regulation of dendritic spine development (GO:0060998)3.52887414
68regulation of vesicle fusion (GO:0031338)3.49417780
69positive regulation of dendritic spine morphogenesis (GO:0061003)3.48853507
70positive regulation of dendritic spine development (GO:0060999)3.43557466
71negative regulation of amino acid transport (GO:0051956)3.43249315
72regulation of female receptivity (GO:0045924)3.43106952
73axonal fasciculation (GO:0007413)3.38750016
74chemosensory behavior (GO:0007635)3.37976889
75long term synaptic depression (GO:0060292)3.37846088
76cellular potassium ion homeostasis (GO:0030007)3.37775118
77behavioral response to cocaine (GO:0048148)3.37400390
78regulation of synaptic transmission, glutamatergic (GO:0051966)3.36596378
79regulation of neurotransmitter secretion (GO:0046928)3.34860839
80presynaptic membrane organization (GO:0097090)3.32666792
81transmission of nerve impulse (GO:0019226)3.29840426
82detection of calcium ion (GO:0005513)3.27623561
83learning (GO:0007612)3.26031742
84proline transport (GO:0015824)3.24009313
85positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.23930339
86innervation (GO:0060384)3.23802590
87regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.23263994
88activation of protein kinase A activity (GO:0034199)3.22428234
89female mating behavior (GO:0060180)3.21235711
90membrane depolarization (GO:0051899)3.20380284
91neurotransmitter transport (GO:0006836)3.19951573
92cerebellar granule cell differentiation (GO:0021707)3.18832208
93regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)3.18256566
94potassium ion homeostasis (GO:0055075)3.17363391
95regulation of respiratory system process (GO:0044065)3.16863340
96regulation of voltage-gated calcium channel activity (GO:1901385)3.16240527
97regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.15625429
98regulation of synapse maturation (GO:0090128)3.13937839
99gamma-aminobutyric acid transport (GO:0015812)3.11391874
100regulation of synaptic transmission (GO:0050804)3.09498211
101neuromuscular process controlling balance (GO:0050885)3.07252096
102synaptic transmission, dopaminergic (GO:0001963)3.06153879
103positive regulation of synaptic transmission (GO:0050806)3.05947958
104regulation of neurotransmitter transport (GO:0051588)3.05082919
105positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02041223
106neuromuscular process (GO:0050905)3.00355014
107synaptic transmission (GO:0007268)3.00347274
108regulation of neurotransmitter levels (GO:0001505)2.99666472
109vesicle transport along microtubule (GO:0047496)2.99487225
110cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.97272989
111outer ear morphogenesis (GO:0042473)2.97239914
112protein K11-linked deubiquitination (GO:0035871)2.97201235
113positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.95111333
114regulation of respiratory gaseous exchange (GO:0043576)2.93438224
115negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.89538786
116regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.88643203
117auditory behavior (GO:0031223)2.87940935
118response to amphetamine (GO:0001975)2.86985080
119cochlea development (GO:0090102)2.85113489
120social behavior (GO:0035176)2.83513303
121intraspecies interaction between organisms (GO:0051703)2.83513303
122cell communication by electrical coupling (GO:0010644)2.82310502
123membrane repolarization (GO:0086009)2.82233509
124neuromuscular process controlling posture (GO:0050884)2.74518603
125negative regulation of oligodendrocyte differentiation (GO:0048715)2.73854354
126cell migration in hindbrain (GO:0021535)2.72620308
127detection of temperature stimulus involved in sensory perception (GO:0050961)2.71308808
128detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.71308808
129cellular sodium ion homeostasis (GO:0006883)2.68996608
130L-amino acid import (GO:0043092)2.67451091
131amino acid import (GO:0043090)2.66693318
132adult walking behavior (GO:0007628)2.63179516
133radial glial cell differentiation (GO:0060019)2.63171483
134behavioral response to nicotine (GO:0035095)2.60119213
135regulation of response to food (GO:0032095)2.59962373
136establishment of mitochondrion localization (GO:0051654)2.59847438
137cerebellar Purkinje cell differentiation (GO:0021702)2.59749303
138regulation of sensory perception (GO:0051931)2.59722661
139regulation of sensory perception of pain (GO:0051930)2.59722661
140neurogenesis (GO:0022008)2.58973352
141telencephalon development (GO:0021537)2.58430557
142neuromuscular synaptic transmission (GO:0007274)2.58398664
143establishment of synaptic vesicle localization (GO:0097480)2.54979075

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.27997146
2GBX2_23144817_ChIP-Seq_PC3_Human3.91253033
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.85716043
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.39514756
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.35346648
6* SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.25221459
7* RARB_27405468_Chip-Seq_BRAIN_Mouse2.92469275
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.91081502
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.86104541
10* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.83983085
11* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.83207563
12* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.83207563
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.71945199
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.71172280
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.66257751
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.63073704
17* EZH2_27304074_Chip-Seq_ESCs_Mouse2.57789452
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.48045474
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.43940375
20* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.32073743
21* REST_18959480_ChIP-ChIP_MESCs_Mouse2.29828012
22DROSHA_22980978_ChIP-Seq_HELA_Human2.27911946
23* RNF2_27304074_Chip-Seq_ESCs_Mouse2.26718884
24* EZH2_27294783_Chip-Seq_ESCs_Mouse2.25657311
25THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.10093358
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.05314217
27* LXR_22292898_ChIP-Seq_THP-1_Human2.03039369
28CTCF_27219007_Chip-Seq_Bcells_Human2.00019522
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.95754305
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94307321
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.93649031
32MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.91771457
33TAF15_26573619_Chip-Seq_HEK293_Human1.86913904
34* TP53_20018659_ChIP-ChIP_R1E_Mouse1.85916942
35KDM2B_26808549_Chip-Seq_K562_Human1.85445351
36AR_21572438_ChIP-Seq_LNCaP_Human1.77538614
37SMAD4_21799915_ChIP-Seq_A2780_Human1.71439094
38ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69234340
39CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.68569971
40SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.65950124
41TET1_21451524_ChIP-Seq_MESCs_Mouse1.63979975
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.62758008
43OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.60805538
44P68_20966046_ChIP-Seq_HELA_Human1.60634800
45ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59409391
46* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56386098
47* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.55079943
48ERG_21242973_ChIP-ChIP_JURKAT_Human1.54356105
49P300_19829295_ChIP-Seq_ESCs_Human1.51492492
50ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.51368657
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.51347854
52ZNF274_21170338_ChIP-Seq_K562_Hela1.46343703
53ZFP281_27345836_Chip-Seq_ESCs_Mouse1.45279320
54SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.44712758
55KDM2B_26808549_Chip-Seq_SUP-B15_Human1.43582439
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43283453
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.40596680
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.40243130
59SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40044165
60PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38782496
61GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.37435202
62TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36726129
63GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35606010
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34093766
65ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.34030818
66SA1_27219007_Chip-Seq_ERYTHROID_Human1.33932693
67AR_25329375_ChIP-Seq_VCAP_Human1.33927840
68SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31882601
69RING1B_27294783_Chip-Seq_ESCs_Mouse1.31717529
70RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29950032
71MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.28884774
72VDR_22108803_ChIP-Seq_LS180_Human1.27866556
73HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.26498461
74* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.26123796
75FUS_26573619_Chip-Seq_HEK293_Human1.26061200
76SOX2_21211035_ChIP-Seq_LN229_Gbm1.25039593
77THAP11_20581084_ChIP-Seq_MESCs_Mouse1.23721122
78CBX2_27304074_Chip-Seq_ESCs_Mouse1.21808412
79TET1_21490601_ChIP-Seq_MESCs_Mouse1.21315591
80TP63_19390658_ChIP-ChIP_HaCaT_Human1.21111738
81* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.20623583
82GATA1_26923725_Chip-Seq_HPCs_Mouse1.19594703
83PIAS1_25552417_ChIP-Seq_VCAP_Human1.17980414
84TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17660255
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17342951
86SMC4_20622854_ChIP-Seq_HELA_Human1.17338146
87KDM2B_26808549_Chip-Seq_JURKAT_Human1.15728759
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.14986761
89CREB1_26743006_Chip-Seq_LNCaP_Human1.13767748
90UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.13494819
91VDR_21846776_ChIP-Seq_THP-1_Human1.13040849
92STAT3_23295773_ChIP-Seq_U87_Human1.13002642
93STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.12252883
94PRDM14_20953172_ChIP-Seq_ESCs_Human1.11926226
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11779400
96DNAJC2_21179169_ChIP-ChIP_NT2_Human1.11512692
97TP53_16413492_ChIP-PET_HCT116_Human1.10579771
98AR_19668381_ChIP-Seq_PC3_Human1.09422780
99KDM2B_26808549_Chip-Seq_DND41_Human1.09211219
100WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08671714
101CTCF_18555785_ChIP-Seq_MESCs_Mouse1.08547912
102UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08164966
103RING1B_27294783_Chip-Seq_NPCs_Mouse1.07780186
104WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06973827
105TCF4_23295773_ChIP-Seq_U87_Human1.04431805
106RARA_24833708_ChIP-Seq_LIVER_Mouse1.04338951
107JUN_21703547_ChIP-Seq_K562_Human1.04047057
108SMAD_19615063_ChIP-ChIP_OVARY_Human1.03748784
109P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03182261
110ARNT_22903824_ChIP-Seq_MCF-7_Human1.01987483
111CTCF_20526341_ChIP-Seq_ESCs_Human1.00569827
112CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00518720
113SA1_27219007_Chip-Seq_Bcells_Human0.99374008
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99289915
115IGF1R_20145208_ChIP-Seq_DFB_Human0.99277002
116RUNX2_22187159_ChIP-Seq_PCA_Human0.98812677
117ZNF217_24962896_ChIP-Seq_MCF-7_Human0.98719018
118BCAT_22108803_ChIP-Seq_LS180_Human0.98519509
119PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.98404978
120TP53_18474530_ChIP-ChIP_U2OS_Human0.97653613
121RNF2_27304074_Chip-Seq_NSC_Mouse0.96775853
122YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95984152
123KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.93381161
124CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92116756
125SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.91903490
126* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.91432964
127NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91423628
128CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91377058
129AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91271876
130AHR_22903824_ChIP-Seq_MCF-7_Human0.91245136
131RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.90281755
132FOXP1_21924763_ChIP-Seq_HESCs_Human0.89748774
133* SMAD3_21741376_ChIP-Seq_ESCs_Human0.89184450
134SMAD3_21741376_ChIP-Seq_HESCs_Human0.88911850
135POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88855102
136TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88855102
137ZFP281_18757296_ChIP-ChIP_E14_Mouse0.87831935
138SOX3_22085726_ChIP-Seq_NPCs_Mouse0.87048238
139TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86971334
140OCT4_19829295_ChIP-Seq_ESCs_Human0.86947280
141NANOG_18555785_Chip-Seq_ESCs_Mouse0.86836065
142KLF4_19829295_ChIP-Seq_ESCs_Human0.86249239
143XRN2_22483619_ChIP-Seq_HELA_Human0.86048806
144KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.85645169
145BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.85099175
146TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.84823145
147SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.83258878
148POU5F1_16518401_ChIP-PET_MESCs_Mouse0.82608817
149NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.81669335
150CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.80609715
151TAF2_19829295_ChIP-Seq_ESCs_Human0.80090637
152RACK7_27058665_Chip-Seq_MCF-7_Human0.79028429
153ELF1_20517297_ChIP-Seq_JURKAT_Human0.76040388
154TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.75873665
155BCL6_27268052_Chip-Seq_Bcells_Human0.75792030
156CTCF_26484167_Chip-Seq_Bcells_Mouse0.75569776
157TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.74994746
158* MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.74475359

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.14717833
2MP0003880_abnormal_central_pattern5.85532612
3MP0003635_abnormal_synaptic_transmissio4.41845009
4MP0004270_analgesia3.80460691
5MP0009745_abnormal_behavioral_response3.70333685
6MP0002063_abnormal_learning/memory/cond3.68087335
7MP0002064_seizures3.25078548
8MP0001968_abnormal_touch/_nociception3.04322725
9MP0002572_abnormal_emotion/affect_behav3.00078997
10MP0002736_abnormal_nociception_after2.65636955
11MP0001501_abnormal_sleep_pattern2.61878010
12MP0009046_muscle_twitch2.61042534
13MP0002822_catalepsy2.60941277
14MP0002272_abnormal_nervous_system2.59925621
15MP0001486_abnormal_startle_reflex2.50731299
16MP0001440_abnormal_grooming_behavior2.38571492
17MP0002734_abnormal_mechanical_nocicepti2.29078498
18MP0005377_hearing/vestibular/ear_phenot2.26382256
19MP0003878_abnormal_ear_physiology2.26382256
20MP0003329_amyloid_beta_deposits2.25044684
21MP0002249_abnormal_larynx_morphology2.20008777
22MP0002735_abnormal_chemical_nociception2.11460557
23MP0009780_abnormal_chondrocyte_physiolo2.11250177
24MP0005423_abnormal_somatic_nervous2.09872069
25MP0002733_abnormal_thermal_nociception1.89375956
26MP0002067_abnormal_sensory_capabilities1.84568970
27MP0001970_abnormal_pain_threshold1.83964445
28MP0001346_abnormal_lacrimal_gland1.78207499
29MP0002909_abnormal_adrenal_gland1.73038889
30MP0003879_abnormal_hair_cell1.72814516
31MP0000778_abnormal_nervous_system1.70007837
32MP0002557_abnormal_social/conspecific_i1.68362008
33MP0004924_abnormal_behavior1.66371303
34MP0005386_behavior/neurological_phenoty1.66371303
35MP0002837_dystrophic_cardiac_calcinosis1.65933642
36MP0004811_abnormal_neuron_physiology1.64378490
37MP0004858_abnormal_nervous_system1.57015631
38MP0002184_abnormal_innervation1.56221401
39MP0001529_abnormal_vocalization1.55891180
40MP0008569_lethality_at_weaning1.52741255
41MP0005646_abnormal_pituitary_gland1.49562182
42MP0010030_abnormal_orbit_morphology1.49480885
43MP0006276_abnormal_autonomic_nervous1.47518035
44MP0001905_abnormal_dopamine_level1.46311026
45MP0000566_synostosis1.43850063
46MP0003787_abnormal_imprinting1.42030386
47MP0001984_abnormal_olfaction1.39489270
48MP0003123_paternal_imprinting1.39265535
49MP0000955_abnormal_spinal_cord1.38794511
50MP0002066_abnormal_motor_capabilities/c1.36382671
51MP0003938_abnormal_ear_development1.33798707
52MP0000026_abnormal_inner_ear1.31049001
53MP0004885_abnormal_endolymph1.30209864
54MP0000678_abnormal_parathyroid_gland1.29859030
55MP0003633_abnormal_nervous_system1.29725962
56MP0001502_abnormal_circadian_rhythm1.29162715
57MP0002882_abnormal_neuron_morphology1.27629041
58MP0000049_abnormal_middle_ear1.21049390
59MP0000681_abnormal_thyroid_gland1.15713654
60MP0001188_hyperpigmentation1.15019523
61MP0004142_abnormal_muscle_tone1.14194959
62MP0003631_nervous_system_phenotype1.11578477
63MP0003075_altered_response_to1.10848598
64MP0002102_abnormal_ear_morphology1.10234265
65MP0000604_amyloidosis1.09473126
66MP0000013_abnormal_adipose_tissue1.09313430
67MP0009379_abnormal_foot_pigmentation1.08077188
68MP0002152_abnormal_brain_morphology1.00917094
69MP0008872_abnormal_physiological_respon0.99997276
70MP0008874_decreased_physiological_sensi0.99739814
71MP0000751_myopathy0.99427297
72MP0005535_abnormal_body_temperature0.97955896
73MP0004510_myositis0.97415834
74MP0002069_abnormal_eating/drinking_beha0.95633695
75MP0004484_altered_response_of0.94803757
76MP0002876_abnormal_thyroid_physiology0.93682227
77MP0009250_abnormal_appendicular_skeleto0.93168699
78MP0005645_abnormal_hypothalamus_physiol0.93133707
79MP0010386_abnormal_urinary_bladder0.92833612
80MP0003122_maternal_imprinting0.92512567
81MP0002653_abnormal_ependyma_morphology0.92010679
82MP0003861_abnormal_nervous_system0.91476161
83MP0004145_abnormal_muscle_electrophysio0.86732832
84MP0004085_abnormal_heartbeat0.84248028
85MP0002277_abnormal_respiratory_mucosa0.83635540
86MP0010234_abnormal_vibrissa_follicle0.83110644
87MP0001963_abnormal_hearing_physiology0.79877371
88MP0002229_neurodegeneration0.79529814
89MP0005409_darkened_coat_color0.76455113
90MP0001664_abnormal_digestion0.75869567
91MP0008961_abnormal_basal_metabolism0.75477902
92MP0006292_abnormal_olfactory_placode0.74837282
93MP0002089_abnormal_postnatal_growth/wei0.74602607
94MP0005167_abnormal_blood-brain_barrier0.74242745
95MP0008877_abnormal_DNA_methylation0.74147052
96MP0003632_abnormal_nervous_system0.72457251
97MP0004742_abnormal_vestibular_system0.72126252
98MP0003136_yellow_coat_color0.72045504
99MP0005551_abnormal_eye_electrophysiolog0.71661351
100MP0001177_atelectasis0.71564055
101MP0004215_abnormal_myocardial_fiber0.71298453
102MP0004133_heterotaxia0.70399576
103MP0005499_abnormal_olfactory_system0.68606211
104MP0005394_taste/olfaction_phenotype0.68606211
105MP0003283_abnormal_digestive_organ0.68515809
106MP0005187_abnormal_penis_morphology0.66945804
107MP0002932_abnormal_joint_morphology0.65835715
108MP0000631_abnormal_neuroendocrine_gland0.65113894
109MP0003634_abnormal_glial_cell0.65052206
110MP0001765_abnormal_ion_homeostasis0.64556496
111MP0003942_abnormal_urinary_system0.64250277
112MP0010769_abnormal_survival0.64239643
113MP0000762_abnormal_tongue_morphology0.63670208
114MP0002081_perinatal_lethality0.63138910
115MP0000579_abnormal_nail_morphology0.63081686
116MP0010768_mortality/aging0.61317437
117MP0001485_abnormal_pinna_reflex0.61053131
118MP0005257_abnormal_intraocular_pressure0.60362676
119MP0004130_abnormal_muscle_cell0.60356750
120MP0005174_abnormal_tail_pigmentation0.59833993
121MP0000920_abnormal_myelination0.59745561
122MP0010770_preweaning_lethality0.59534136
123MP0002752_abnormal_somatic_nervous0.58889504
124MP0005623_abnormal_meninges_morphology0.58178673
125MP0004233_abnormal_muscle_weight0.57644700
126MP0002234_abnormal_pharynx_morphology0.54851536
127MP0002090_abnormal_vision0.53000453
128MP0003137_abnormal_impulse_conducting0.50651398
129MP0003690_abnormal_glial_cell0.49246263
130MP0005166_decreased_susceptibility_to0.48851532
131MP0004043_abnormal_pH_regulation0.48814659
132MP0001943_abnormal_respiration0.47599541
133MP0005379_endocrine/exocrine_gland_phen0.47147259

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.60185331
2Myokymia (HP:0002411)7.13672788
3Visual hallucinations (HP:0002367)6.14254874
4Focal seizures (HP:0007359)6.10210160
5Epileptic encephalopathy (HP:0200134)5.60441087
6Atonic seizures (HP:0010819)5.58743681
7Absence seizures (HP:0002121)4.78911596
8Febrile seizures (HP:0002373)4.67769255
9Dialeptic seizures (HP:0011146)4.42640591
10Hyperventilation (HP:0002883)4.35166910
11Generalized tonic-clonic seizures (HP:0002069)4.24530015
12Cerebral inclusion bodies (HP:0100314)3.97922092
13Amblyopia (HP:0000646)3.96711667
14Congenital malformation of the right heart (HP:0011723)3.87160155
15Double outlet right ventricle (HP:0001719)3.87160155
16Progressive cerebellar ataxia (HP:0002073)3.77572005
17Broad-based gait (HP:0002136)3.75452475
18Supranuclear gaze palsy (HP:0000605)3.55738544
19Poor eye contact (HP:0000817)3.54465443
20Anxiety (HP:0000739)3.41078590
21Partial duplication of thumb phalanx (HP:0009944)3.37886010
22Impaired vibration sensation in the lower limbs (HP:0002166)3.36066461
23Truncus arteriosus (HP:0001660)3.30861938
24Dysmetria (HP:0001310)3.30735432
25Action tremor (HP:0002345)3.30118599
26Depression (HP:0000716)3.28974952
27Neurofibrillary tangles (HP:0002185)3.24032372
28Gaze-evoked nystagmus (HP:0000640)3.15331322
29Dysdiadochokinesis (HP:0002075)3.14114257
30Impaired social interactions (HP:0000735)3.08690970
31Abnormal social behavior (HP:0012433)3.08690970
32Drooling (HP:0002307)3.06628458
33Excessive salivation (HP:0003781)3.06628458
34Hyperthyroidism (HP:0000836)3.06247529
35Partial duplication of the phalanx of hand (HP:0009999)3.01734291
36Epileptiform EEG discharges (HP:0011182)2.97725375
37Delusions (HP:0000746)2.96294677
38Abnormality of the aortic arch (HP:0012303)2.91887199
39Truncal ataxia (HP:0002078)2.91867283
40Aplasia involving bones of the upper limbs (HP:0009823)2.81465788
41Aplasia of the phalanges of the hand (HP:0009802)2.81465788
42Aplasia involving bones of the extremities (HP:0009825)2.81465788
43Nonprogressive disorder (HP:0003680)2.78921159
44Abnormality of the lower motor neuron (HP:0002366)2.76946069
45Dynein arm defect of respiratory motile cilia (HP:0012255)2.74983733
46Absent/shortened dynein arms (HP:0200106)2.74983733
47Hypoplastic left heart (HP:0004383)2.69346283
48Diplopia (HP:0000651)2.68646577
49Abnormality of binocular vision (HP:0011514)2.68646577
50Cerebral hypomyelination (HP:0006808)2.67971344
51Impaired smooth pursuit (HP:0007772)2.67904254
52Urinary bladder sphincter dysfunction (HP:0002839)2.67655266
53Alacrima (HP:0000522)2.66377874
54EEG with generalized epileptiform discharges (HP:0011198)2.64882122
55Abnormal eating behavior (HP:0100738)2.64409300
56Postural instability (HP:0002172)2.62522541
57Bradykinesia (HP:0002067)2.62472116
58Hemiparesis (HP:0001269)2.62029210
59Stereotypic behavior (HP:0000733)2.58945462
60Mutism (HP:0002300)2.55210218
61Ankle clonus (HP:0011448)2.51851340
62Absent speech (HP:0001344)2.51317532
63Focal dystonia (HP:0004373)2.50424152
64Torticollis (HP:0000473)2.45733335
65Progressive inability to walk (HP:0002505)2.44851691
66Hypsarrhythmia (HP:0002521)2.41887631
67Inability to walk (HP:0002540)2.36933206
68Atelectasis (HP:0100750)2.36582607
69Limb dystonia (HP:0002451)2.35076042
70Decreased central vision (HP:0007663)2.32337257
71Generalized myoclonic seizures (HP:0002123)2.31538665
72Hypoplastic heart (HP:0001961)2.30295573
73Status epilepticus (HP:0002133)2.28447810
74Urinary urgency (HP:0000012)2.28331722
75Split foot (HP:0001839)2.26622265
76Impaired vibratory sensation (HP:0002495)2.25342836
77Termporal pattern (HP:0011008)2.24988335
78Insidious onset (HP:0003587)2.24988335
79Neoplasm of the adrenal cortex (HP:0100641)2.24053356
80Scanning speech (HP:0002168)2.23447113
81Annular pancreas (HP:0001734)2.22302792
82Incomplete penetrance (HP:0003829)2.20735558
83Periauricular skin pits (HP:0100277)2.19093240
84Preauricular pit (HP:0004467)2.19093240
85Genetic anticipation (HP:0003743)2.18168779
86Hydroureter (HP:0000072)2.16908311
87Megalencephaly (HP:0001355)2.16624227
88Nasal speech (HP:0001611)2.14934332
89Papilledema (HP:0001085)2.14258359
90Abnormal ventriculo-arterial connection (HP:0011563)2.13192772
91Transposition of the great arteries (HP:0001669)2.13192772
92Abnormal connection of the cardiac segments (HP:0011545)2.13192772
93Abnormality of ocular smooth pursuit (HP:0000617)2.12176303
94Craniofacial dystonia (HP:0012179)2.11703755
95Myopathic facies (HP:0002058)2.11291479
96Decreased lacrimation (HP:0000633)2.10105538
97Abnormality of salivation (HP:0100755)2.08861092
98Spastic gait (HP:0002064)2.07911435
99Protruding tongue (HP:0010808)2.07449867
100Ventricular fibrillation (HP:0001663)2.07363822
101Fetal akinesia sequence (HP:0001989)2.06719816
102Psychosis (HP:0000709)2.06695026
103Rapidly progressive (HP:0003678)2.05091883
104Dysmetric saccades (HP:0000641)2.04783006
105Resting tremor (HP:0002322)2.02549815
106Intention tremor (HP:0002080)2.01599856
107Spastic tetraparesis (HP:0001285)1.99961910
108Sleep apnea (HP:0010535)1.98147893
109Maternal diabetes (HP:0009800)1.97859352
110Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.95257724
111Broad distal phalanx of finger (HP:0009836)1.95210057
112Apathy (HP:0000741)1.92898626
113Turricephaly (HP:0000262)1.91946817
114Abnormal EKG (HP:0003115)1.91023637
115Optic nerve coloboma (HP:0000588)1.90976472
116Lower limb muscle weakness (HP:0007340)1.90544363
117Thickened helices (HP:0000391)1.90192404
118Gait ataxia (HP:0002066)1.89857684
119Obstructive sleep apnea (HP:0002870)1.89516108
120Septo-optic dysplasia (HP:0100842)1.86379094
121Abnormality of the corticospinal tract (HP:0002492)1.86189578
122Akinesia (HP:0002304)1.85236297
123Global brain atrophy (HP:0002283)1.84091432
124Palpebral edema (HP:0100540)1.81768258
125Amyotrophic lateral sclerosis (HP:0007354)1.81487750
126Blue irides (HP:0000635)1.81141515
127Lower limb asymmetry (HP:0100559)1.80428008
128Pheochromocytoma (HP:0002666)1.79898030
129Retinal dysplasia (HP:0007973)1.79569446
130Unsteady gait (HP:0002317)1.79409990
131Insomnia (HP:0100785)1.78539864
132Type II lissencephaly (HP:0007260)1.78152029
133Hypoplasia of the radius (HP:0002984)1.76730356
134Polyphagia (HP:0002591)1.76565453
135Recurrent corneal erosions (HP:0000495)1.75424741
136Clonus (HP:0002169)1.75048482
137Hemiplegia (HP:0002301)1.74230010
138Testicular atrophy (HP:0000029)1.74165706
139Ankyloglossia (HP:0010296)1.71688236
140Lower limb amyotrophy (HP:0007210)1.71680984
141Rigidity (HP:0002063)1.70371373
142Sclerocornea (HP:0000647)1.69660427
143Inappropriate behavior (HP:0000719)1.69221983
144Acute necrotizing encephalopathy (HP:0006965)1.68985227
145Spastic diplegia (HP:0001264)1.67642956
146Rib fusion (HP:0000902)1.66852322
147Pointed chin (HP:0000307)1.66096490
148Deep palmar crease (HP:0006191)1.66089037
149Prolonged QT interval (HP:0001657)1.65917848

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.93723929
2NTRK34.35545714
3SMG13.69872172
4MAP3K93.52988593
5RIPK43.52376954
6DAPK22.84786998
7TAF12.67760778
8MAP3K122.66698489
9MAP3K42.63852594
10CAMK1D2.61182390
11MINK12.49396341
12VRK22.34156599
13KSR22.32890456
14CASK2.29347702
15MAP2K72.26357774
16PLK22.25715978
17DAPK12.23040991
18ARAF2.17236079
19CAMK1G2.12003616
20MAPK152.02089858
21KSR12.01621868
22PAK61.93304132
23BCKDK1.79668375
24MAP3K131.77310967
25MARK11.76151230
26PTK2B1.76149005
27GRK51.76097695
28MAP2K41.71177521
29PRKD31.65212155
30BMPR21.64098118
31CDK191.61365601
32NTRK11.49315717
33CAMKK11.48981492
34PNCK1.48451419
35CDK51.46824476
36NME11.46068478
37SIK21.42406891
38PRPF4B1.32182376
39PRKCG1.30191331
40NTRK21.28892003
41RAF11.28667953
42FES1.24553002
43STK161.20177709
44IRAK21.18642076
45CAMK2A1.14726984
46FGR1.14466920
47TNIK1.08840014
48MAP3K21.08006547
49BRSK11.03544735
50MAPKAPK51.01513159
51CAMK2B1.00770463
52CAMKK21.00455203
53WNK11.00213128
54MAPK130.91639679
55ICK0.91142415
56WNK40.89427458
57NME20.87963141
58STK380.87900461
59TYRO30.85255831
60GRK60.84807970
61OXSR10.84184093
62CDK180.83992557
63CAMK10.82756560
64MAP3K110.82674967
65EEF2K0.82283767
66DYRK20.82130435
67CSNK1G30.80741676
68CDK140.80576299
69CDK150.79057267
70CSNK1A1L0.77451240
71PKN10.74798272
72UHMK10.73380189
73STK390.71982838
74SIK30.69616645
75DAPK30.69358319
76CDK11A0.69095550
77DYRK1A0.68284227
78FGFR20.67278530
79PDK10.65271478
80STK110.64388968
81DYRK30.63556821
82AURKA0.63360571
83SGK10.62552414
84MAP3K10.61400686
85CSNK1G10.60772596
86IRAK30.60644487
87PDPK10.60589567
88CCNB10.60223794
89AKT20.59309409
90PINK10.59174514
91BRAF0.58866901
92PRKD20.55927933
93FER0.54756049
94PAK30.53980751
95LATS20.53716495
96SGK2230.52558322
97SGK4940.52558322
98RET0.52478592
99BCR0.51598318
100PRKCE0.51352920
101TAOK10.51176277
102MAP2K10.51093502
103MARK20.49071770
104MAPK40.48935773
105CAMK2D0.48132174
106MOS0.47780187
107TRIB30.46407381
108TNK20.45926637
109PRKCZ0.45857001
110PRKCH0.45853094
111SGK30.45503594
112MAP3K100.44034442
113CSNK1G20.42756075
114MAP3K60.41012731
115ABL20.40934437
116CAMK2G0.38867912
117MAP3K70.37470470
118FYN0.36612018
119PRKAA10.36447569
120CSNK1E0.35696230
121RPS6KA30.35548324
122SGK20.34641208
123CAMK40.33356205
124ROCK20.32883032
125ADRBK10.31683359
126MAPK120.31333921
127LIMK10.31261818
128GRK70.31075851
129CHEK20.31030159
130MAPK100.30404712
131PRKCA0.29726184
132NEK60.29083856
133DMPK0.28265142
134AKT30.28039489
135SYK0.28037474
136PRKACA0.27023727
137PHKG20.26332847
138PHKG10.26332847

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.89856390
2Sulfur relay system_Homo sapiens_hsa041223.54324530
3Synaptic vesicle cycle_Homo sapiens_hsa047213.20580527
4Long-term potentiation_Homo sapiens_hsa047203.18417704
5Circadian entrainment_Homo sapiens_hsa047132.85703990
6Amphetamine addiction_Homo sapiens_hsa050312.82340456
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.81127842
8Olfactory transduction_Homo sapiens_hsa047402.70608965
9Glutamatergic synapse_Homo sapiens_hsa047242.64703171
10Morphine addiction_Homo sapiens_hsa050322.54368219
11GABAergic synapse_Homo sapiens_hsa047272.51963850
12Salivary secretion_Homo sapiens_hsa049702.36440219
13Dopaminergic synapse_Homo sapiens_hsa047282.21266377
14Vitamin B6 metabolism_Homo sapiens_hsa007502.18109789
15Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.16909319
16Collecting duct acid secretion_Homo sapiens_hsa049662.06068231
17Insulin secretion_Homo sapiens_hsa049112.00569160
18Gastric acid secretion_Homo sapiens_hsa049711.94663609
19Renin secretion_Homo sapiens_hsa049241.94616262
20Taste transduction_Homo sapiens_hsa047421.91513895
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.86760321
22Cholinergic synapse_Homo sapiens_hsa047251.81196276
23Calcium signaling pathway_Homo sapiens_hsa040201.80844203
24Oxytocin signaling pathway_Homo sapiens_hsa049211.79950194
25Serotonergic synapse_Homo sapiens_hsa047261.75924364
26Long-term depression_Homo sapiens_hsa047301.72853071
27Ribosome_Homo sapiens_hsa030101.63730834
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56584059
29Cocaine addiction_Homo sapiens_hsa050301.53089472
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.51438072
31GnRH signaling pathway_Homo sapiens_hsa049121.46723576
32Notch signaling pathway_Homo sapiens_hsa043301.42165937
33Gap junction_Homo sapiens_hsa045401.34646527
34Cardiac muscle contraction_Homo sapiens_hsa042601.31956402
35Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.31857561
36Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29875512
37cAMP signaling pathway_Homo sapiens_hsa040241.29353518
38Vibrio cholerae infection_Homo sapiens_hsa051101.29216127
39Oxidative phosphorylation_Homo sapiens_hsa001901.28268863
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26228270
41Alzheimers disease_Homo sapiens_hsa050101.25185918
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.24911883
43Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.17289672
44Glioma_Homo sapiens_hsa052141.16196235
45Basal cell carcinoma_Homo sapiens_hsa052171.15108207
46Arginine and proline metabolism_Homo sapiens_hsa003301.14475193
47Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13455636
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12687915
49cGMP-PKG signaling pathway_Homo sapiens_hsa040221.10778210
50Phosphatidylinositol signaling system_Homo sapiens_hsa040701.10653015
51Estrogen signaling pathway_Homo sapiens_hsa049151.10124867
52Melanogenesis_Homo sapiens_hsa049161.09799750
53Hedgehog signaling pathway_Homo sapiens_hsa043401.04907113
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.01850395
55Vascular smooth muscle contraction_Homo sapiens_hsa042701.01062908
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.00162702
57Axon guidance_Homo sapiens_hsa043600.99539572
58Phototransduction_Homo sapiens_hsa047440.96505780
59Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.91732703
60Type II diabetes mellitus_Homo sapiens_hsa049300.91619549
61Parkinsons disease_Homo sapiens_hsa050120.90638075
62Oocyte meiosis_Homo sapiens_hsa041140.87094028
63Pancreatic secretion_Homo sapiens_hsa049720.87021990
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.85767833
65ErbB signaling pathway_Homo sapiens_hsa040120.84921774
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.83939725
67Fatty acid biosynthesis_Homo sapiens_hsa000610.83657211
68Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.82688490
69VEGF signaling pathway_Homo sapiens_hsa043700.78294216
70Thyroid hormone synthesis_Homo sapiens_hsa049180.71571957
71Glucagon signaling pathway_Homo sapiens_hsa049220.69265151
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.68057952
73African trypanosomiasis_Homo sapiens_hsa051430.67111733
74Choline metabolism in cancer_Homo sapiens_hsa052310.66906643
75Huntingtons disease_Homo sapiens_hsa050160.65978496
76Hippo signaling pathway_Homo sapiens_hsa043900.60789723
77Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.60044416
78Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.60030605
79Cysteine and methionine metabolism_Homo sapiens_hsa002700.59669581
80Dilated cardiomyopathy_Homo sapiens_hsa054140.58798604
81Dorso-ventral axis formation_Homo sapiens_hsa043200.58638285
82MAPK signaling pathway_Homo sapiens_hsa040100.56354440
83Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55517977
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.51978723
85Ras signaling pathway_Homo sapiens_hsa040140.51306201
86Prion diseases_Homo sapiens_hsa050200.51032714
87Rap1 signaling pathway_Homo sapiens_hsa040150.50978780
88Biosynthesis of amino acids_Homo sapiens_hsa012300.48709522
89Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48703757
90Pyruvate metabolism_Homo sapiens_hsa006200.46566228
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.46103833
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.44220166
93Mineral absorption_Homo sapiens_hsa049780.41998857
94Alcoholism_Homo sapiens_hsa050340.40866873
95Rheumatoid arthritis_Homo sapiens_hsa053230.39757330
96Inositol phosphate metabolism_Homo sapiens_hsa005620.38398731
97Nitrogen metabolism_Homo sapiens_hsa009100.38286643
98Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34873038
99Type I diabetes mellitus_Homo sapiens_hsa049400.34868633
100Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.34804353
101Bile secretion_Homo sapiens_hsa049760.34787604
102Non-small cell lung cancer_Homo sapiens_hsa052230.34517903
103Wnt signaling pathway_Homo sapiens_hsa043100.34351271
104Circadian rhythm_Homo sapiens_hsa047100.34154640
105Melanoma_Homo sapiens_hsa052180.31350186
106Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.29655590
107Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28239374
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27555740
109Endocytosis_Homo sapiens_hsa041440.27508482
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.27156963
111mTOR signaling pathway_Homo sapiens_hsa041500.26580984
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.25812212
113Insulin signaling pathway_Homo sapiens_hsa049100.24149335
114Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.23816644
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.22559483
116Renal cell carcinoma_Homo sapiens_hsa052110.22531636
117Chemokine signaling pathway_Homo sapiens_hsa040620.22064969
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.19558349
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.18802418
120SNARE interactions in vesicular transport_Homo sapiens_hsa041300.18535663
121Ovarian steroidogenesis_Homo sapiens_hsa049130.17527503
122Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.17285339

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »