

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.16493647 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.16493647 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.09398727 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 5.56902025 |
| 5 | chaperone-mediated protein transport (GO:0072321) | 5.23626004 |
| 6 | ribosomal small subunit biogenesis (GO:0042274) | 5.20008270 |
| 7 | viral transcription (GO:0019083) | 4.92323383 |
| 8 | translational termination (GO:0006415) | 4.72239972 |
| 9 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.67415676 |
| 10 | behavioral response to nicotine (GO:0035095) | 4.67365113 |
| 11 | platelet dense granule organization (GO:0060155) | 4.63389832 |
| 12 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.47313788 |
| 13 | respiratory electron transport chain (GO:0022904) | 4.33630311 |
| 14 | electron transport chain (GO:0022900) | 4.29021245 |
| 15 | translational elongation (GO:0006414) | 4.13773727 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.05896478 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 4.03406140 |
| 18 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.02424417 |
| 19 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.02424417 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.02424417 |
| 21 | protein complex biogenesis (GO:0070271) | 4.01314003 |
| 22 | protein targeting to ER (GO:0045047) | 4.01292863 |
| 23 | maturation of SSU-rRNA (GO:0030490) | 3.89778437 |
| 24 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.87431926 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.84255684 |
| 26 | protein localization to endoplasmic reticulum (GO:0070972) | 3.80203172 |
| 27 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.77304731 |
| 28 | viral life cycle (GO:0019058) | 3.67237672 |
| 29 | cellular protein complex disassembly (GO:0043624) | 3.65631953 |
| 30 | ATP biosynthetic process (GO:0006754) | 3.64285615 |
| 31 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.62809357 |
| 32 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.58950233 |
| 33 | GTP biosynthetic process (GO:0006183) | 3.58134542 |
| 34 | indolalkylamine metabolic process (GO:0006586) | 3.50717926 |
| 35 | opioid receptor signaling pathway (GO:0038003) | 3.47308399 |
| 36 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.42528249 |
| 37 | ribosomal large subunit biogenesis (GO:0042273) | 3.34943924 |
| 38 | translational initiation (GO:0006413) | 3.28411307 |
| 39 | protein-cofactor linkage (GO:0018065) | 3.23624297 |
| 40 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.23370099 |
| 41 | DNA deamination (GO:0045006) | 3.21791810 |
| 42 | alkaloid metabolic process (GO:0009820) | 3.20652841 |
| 43 | hydrogen ion transmembrane transport (GO:1902600) | 3.20118748 |
| 44 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.18958728 |
| 45 | UTP biosynthetic process (GO:0006228) | 3.18048363 |
| 46 | translation (GO:0006412) | 3.16999972 |
| 47 | pseudouridine synthesis (GO:0001522) | 3.16271843 |
| 48 | protein neddylation (GO:0045116) | 3.13787083 |
| 49 | UTP metabolic process (GO:0046051) | 3.09639362 |
| 50 | cellular component biogenesis (GO:0044085) | 3.08262241 |
| 51 | serotonin metabolic process (GO:0042428) | 3.08018739 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.03891789 |
| 53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.03436765 |
| 54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.03386826 |
| 55 | termination of RNA polymerase III transcription (GO:0006386) | 3.03386826 |
| 56 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.01934842 |
| 57 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.01934842 |
| 58 | postsynaptic membrane organization (GO:0001941) | 3.00815237 |
| 59 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.99732359 |
| 60 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.99732359 |
| 61 | protein complex disassembly (GO:0043241) | 2.98455472 |
| 62 | primary amino compound metabolic process (GO:1901160) | 2.94377741 |
| 63 | hydrogen transport (GO:0006818) | 2.93484287 |
| 64 | proton transport (GO:0015992) | 2.93273106 |
| 65 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.93091734 |
| 66 | macromolecular complex disassembly (GO:0032984) | 2.89218497 |
| 67 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.88336883 |
| 68 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.84767144 |
| 69 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.82413763 |
| 70 | inositol phosphate dephosphorylation (GO:0046855) | 2.82413763 |
| 71 | epithelial cilium movement (GO:0003351) | 2.81017381 |
| 72 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.80646648 |
| 73 | inositol phosphate catabolic process (GO:0071545) | 2.78960058 |
| 74 | respiratory chain complex IV assembly (GO:0008535) | 2.74941732 |
| 75 | chromatin remodeling at centromere (GO:0031055) | 2.72909724 |
| 76 | regulation of action potential (GO:0098900) | 2.66372489 |
| 77 | positive regulation of prostaglandin secretion (GO:0032308) | 2.65156518 |
| 78 | rRNA processing (GO:0006364) | 2.61874967 |
| 79 | protein deneddylation (GO:0000338) | 2.60966153 |
| 80 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.60149665 |
| 81 | rRNA metabolic process (GO:0016072) | 2.59734944 |
| 82 | cullin deneddylation (GO:0010388) | 2.58993106 |
| 83 | response to pheromone (GO:0019236) | 2.58819274 |
| 84 | cornea development in camera-type eye (GO:0061303) | 2.57352991 |
| 85 | protein targeting to mitochondrion (GO:0006626) | 2.56784629 |
| 86 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.55691629 |
| 87 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.55416397 |
| 88 | establishment of protein localization to mitochondrion (GO:0072655) | 2.54894040 |
| 89 | neuron fate determination (GO:0048664) | 2.54842918 |
| 90 | behavioral response to ethanol (GO:0048149) | 2.54108839 |
| 91 | cell proliferation in forebrain (GO:0021846) | 2.54044251 |
| 92 | replication fork processing (GO:0031297) | 2.52943166 |
| 93 | protein polyglutamylation (GO:0018095) | 2.52898847 |
| 94 | anterograde synaptic vesicle transport (GO:0048490) | 2.52343099 |
| 95 | protein targeting to membrane (GO:0006612) | 2.49962822 |
| 96 | indole-containing compound metabolic process (GO:0042430) | 2.49086375 |
| 97 | regulation of prostaglandin secretion (GO:0032306) | 2.48399434 |
| 98 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.47815084 |
| 99 | rhodopsin mediated signaling pathway (GO:0016056) | 2.47739599 |
| 100 | tRNA processing (GO:0008033) | 2.47158281 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.15098569 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.63386642 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.35114000 |
| 4 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.00568083 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.98876134 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.96237193 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.90965811 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.82464722 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.82060428 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.74861496 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.36208286 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.34042296 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.04196282 |
| 14 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.88362541 |
| 15 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.82661260 |
| 16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.80985626 |
| 17 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.79911224 |
| 18 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.79611254 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.78343621 |
| 20 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.73091863 |
| 21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.67379997 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.65706974 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.64517837 |
| 24 | FUS_26573619_Chip-Seq_HEK293_Human | 1.63673094 |
| 25 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.61347634 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.59736597 |
| 27 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.59640713 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.58281171 |
| 29 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.51642530 |
| 30 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.50026016 |
| 31 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.49403418 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.48663504 |
| 33 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.47915248 |
| 34 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.41376730 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40550723 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.38782581 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.35604704 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.34051044 |
| 39 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.31339907 |
| 40 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.30165173 |
| 41 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29538399 |
| 42 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.28843741 |
| 43 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.27101132 |
| 44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.26925953 |
| 45 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.24325003 |
| 46 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.24280422 |
| 47 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.19886293 |
| 48 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.17970096 |
| 49 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.17372627 |
| 50 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.17372627 |
| 51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.16303152 |
| 52 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.15470302 |
| 53 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.15297580 |
| 54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.15125515 |
| 55 | ERA_21632823_ChIP-Seq_H3396_Human | 1.12888863 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.12355224 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.12355224 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.12235244 |
| 59 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.12187474 |
| 60 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.12132094 |
| 61 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10745056 |
| 62 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.10336188 |
| 63 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.10324273 |
| 64 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.09608248 |
| 65 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.08421201 |
| 66 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08245508 |
| 67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08004949 |
| 68 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.06621327 |
| 69 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06459451 |
| 70 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.05454426 |
| 71 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.04488829 |
| 72 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.03322519 |
| 73 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.01080761 |
| 74 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98412829 |
| 75 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.97613609 |
| 76 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.97574333 |
| 77 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95343843 |
| 78 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.94808127 |
| 79 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.94483324 |
| 80 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94155742 |
| 81 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.93886709 |
| 82 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.92915474 |
| 83 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.92669509 |
| 84 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92360336 |
| 85 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.92240679 |
| 86 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.91865210 |
| 87 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.90757822 |
| 88 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.90600182 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89454852 |
| 90 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.89278975 |
| 91 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.88616826 |
| 92 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.87857052 |
| 93 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.86698575 |
| 94 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.86435062 |
| 95 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85641273 |
| 96 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.84824780 |
| 97 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.84584441 |
| 98 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.84021163 |
| 99 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.83294269 |
| 100 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.82135874 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.30910768 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.25310353 |
| 3 | MP0003011_delayed_dark_adaptation | 3.65709935 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.81362072 |
| 5 | MP0003122_maternal_imprinting | 2.67309668 |
| 6 | MP0002638_abnormal_pupillary_reflex | 2.66650152 |
| 7 | MP0005083_abnormal_biliary_tract | 2.65247878 |
| 8 | MP0003787_abnormal_imprinting | 2.54379787 |
| 9 | MP0001529_abnormal_vocalization | 2.53496344 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.37310393 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.25066862 |
| 12 | MP0003121_genomic_imprinting | 2.23089801 |
| 13 | MP0002163_abnormal_gland_morphology | 2.10983373 |
| 14 | MP0002160_abnormal_reproductive_system | 2.09790233 |
| 15 | MP0005551_abnormal_eye_electrophysiolog | 1.97187350 |
| 16 | MP0005379_endocrine/exocrine_gland_phen | 1.89223758 |
| 17 | MP0005645_abnormal_hypothalamus_physiol | 1.87397977 |
| 18 | MP0004142_abnormal_muscle_tone | 1.86652833 |
| 19 | MP0001919_abnormal_reproductive_system | 1.84413640 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 1.76942466 |
| 21 | MP0005389_reproductive_system_phenotype | 1.72314164 |
| 22 | MP0009046_muscle_twitch | 1.69489718 |
| 23 | MP0000778_abnormal_nervous_system | 1.64354908 |
| 24 | MP0000569_abnormal_digit_pigmentation | 1.58424796 |
| 25 | MP0005253_abnormal_eye_physiology | 1.58315721 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.56721656 |
| 27 | MP0002102_abnormal_ear_morphology | 1.56656121 |
| 28 | MP0005394_taste/olfaction_phenotype | 1.56355452 |
| 29 | MP0005499_abnormal_olfactory_system | 1.56355452 |
| 30 | MP0005085_abnormal_gallbladder_physiolo | 1.55965140 |
| 31 | MP0002272_abnormal_nervous_system | 1.54428451 |
| 32 | MP0009745_abnormal_behavioral_response | 1.52524381 |
| 33 | MP0003123_paternal_imprinting | 1.52390632 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.50437682 |
| 35 | MP0005075_abnormal_melanosome_morpholog | 1.48445364 |
| 36 | MP0003646_muscle_fatigue | 1.47005776 |
| 37 | MP0003880_abnormal_central_pattern | 1.46016018 |
| 38 | MP0002837_dystrophic_cardiac_calcinosis | 1.42956410 |
| 39 | MP0002184_abnormal_innervation | 1.40265696 |
| 40 | MP0001293_anophthalmia | 1.39308775 |
| 41 | MP0002234_abnormal_pharynx_morphology | 1.35863735 |
| 42 | MP0000631_abnormal_neuroendocrine_gland | 1.34190415 |
| 43 | MP0001905_abnormal_dopamine_level | 1.32429840 |
| 44 | MP0001764_abnormal_homeostasis | 1.30293984 |
| 45 | MP0005646_abnormal_pituitary_gland | 1.27862657 |
| 46 | MP0008872_abnormal_physiological_respon | 1.27526189 |
| 47 | MP0004147_increased_porphyrin_level | 1.26884344 |
| 48 | MP0002572_abnormal_emotion/affect_behav | 1.25990347 |
| 49 | MP0002736_abnormal_nociception_after | 1.23233614 |
| 50 | MP0002876_abnormal_thyroid_physiology | 1.22918472 |
| 51 | MP0002938_white_spotting | 1.22697340 |
| 52 | MP0003195_calcinosis | 1.22689940 |
| 53 | MP0005365_abnormal_bile_salt | 1.20065869 |
| 54 | MP0005377_hearing/vestibular/ear_phenot | 1.18213061 |
| 55 | MP0003878_abnormal_ear_physiology | 1.18213061 |
| 56 | MP0002733_abnormal_thermal_nociception | 1.17349530 |
| 57 | MP0003806_abnormal_nucleotide_metabolis | 1.17100786 |
| 58 | MP0008875_abnormal_xenobiotic_pharmacok | 1.16604821 |
| 59 | MP0005423_abnormal_somatic_nervous | 1.13475662 |
| 60 | MP0001440_abnormal_grooming_behavior | 1.13214762 |
| 61 | MP0002557_abnormal_social/conspecific_i | 1.11703894 |
| 62 | MP0005195_abnormal_posterior_eye | 1.11277654 |
| 63 | MP0003635_abnormal_synaptic_transmissio | 1.10055099 |
| 64 | MP0002064_seizures | 1.08970682 |
| 65 | MP0003693_abnormal_embryo_hatching | 1.08275556 |
| 66 | MP0001485_abnormal_pinna_reflex | 1.07911078 |
| 67 | MP0000372_irregular_coat_pigmentation | 1.07793666 |
| 68 | MP0001970_abnormal_pain_threshold | 1.06163782 |
| 69 | MP0000049_abnormal_middle_ear | 1.05471418 |
| 70 | MP0002735_abnormal_chemical_nociception | 1.04837190 |
| 71 | MP0001984_abnormal_olfaction | 1.04717837 |
| 72 | MP0004742_abnormal_vestibular_system | 1.02859549 |
| 73 | MP0002752_abnormal_somatic_nervous | 1.01449037 |
| 74 | MP0004145_abnormal_muscle_electrophysio | 1.00714361 |
| 75 | MP0002653_abnormal_ependyma_morphology | 0.95781985 |
| 76 | MP0004885_abnormal_endolymph | 0.95398638 |
| 77 | MP0002063_abnormal_learning/memory/cond | 0.93101188 |
| 78 | MP0005386_behavior/neurological_phenoty | 0.92975283 |
| 79 | MP0004924_abnormal_behavior | 0.92975283 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.92153442 |
| 81 | MP0004043_abnormal_pH_regulation | 0.91445833 |
| 82 | MP0001486_abnormal_startle_reflex | 0.91228038 |
| 83 | MP0005174_abnormal_tail_pigmentation | 0.88725451 |
| 84 | MP0008058_abnormal_DNA_repair | 0.88449160 |
| 85 | MP0010030_abnormal_orbit_morphology | 0.87849504 |
| 86 | MP0004133_heterotaxia | 0.87845268 |
| 87 | MP0005391_vision/eye_phenotype | 0.84625544 |
| 88 | MP0001188_hyperpigmentation | 0.83071410 |
| 89 | MP0004859_abnormal_synaptic_plasticity | 0.82926449 |
| 90 | MP0002067_abnormal_sensory_capabilities | 0.82447761 |
| 91 | MP0002095_abnormal_skin_pigmentation | 0.81323723 |
| 92 | MP0000955_abnormal_spinal_cord | 0.79506734 |
| 93 | MP0003718_maternal_effect | 0.75674711 |
| 94 | MP0010386_abnormal_urinary_bladder | 0.75264136 |
| 95 | MP0002734_abnormal_mechanical_nocicepti | 0.74335100 |
| 96 | MP0003283_abnormal_digestive_organ | 0.73872351 |
| 97 | MP0003938_abnormal_ear_development | 0.73825623 |
| 98 | MP0000026_abnormal_inner_ear | 0.73783457 |
| 99 | MP0003698_abnormal_male_reproductive | 0.72971888 |
| 100 | MP0002210_abnormal_sex_determination | 0.71541593 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.77013497 |
| 2 | Limb dystonia (HP:0002451) | 4.41471532 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.20975164 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.18223623 |
| 5 | Acute encephalopathy (HP:0006846) | 3.99406464 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.96110967 |
| 7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.82083649 |
| 8 | Increased CSF lactate (HP:0002490) | 3.81104706 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.66175506 |
| 10 | Abnormality of midbrain morphology (HP:0002418) | 3.66175506 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.42637644 |
| 12 | Abnormal number of erythroid precursors (HP:0012131) | 3.42544859 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.32352419 |
| 14 | Hepatocellular necrosis (HP:0001404) | 3.28444271 |
| 15 | Hypothermia (HP:0002045) | 3.27148810 |
| 16 | Hepatic necrosis (HP:0002605) | 3.20714112 |
| 17 | Exertional dyspnea (HP:0002875) | 3.13644797 |
| 18 | 3-Methylglutaconic aciduria (HP:0003535) | 3.11018583 |
| 19 | Lipid accumulation in hepatocytes (HP:0006561) | 3.09864493 |
| 20 | Limb hypertonia (HP:0002509) | 3.01073290 |
| 21 | Type II lissencephaly (HP:0007260) | 2.95177934 |
| 22 | Medial flaring of the eyebrow (HP:0010747) | 2.95137505 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.89956333 |
| 24 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.89956333 |
| 25 | Cerebral edema (HP:0002181) | 2.89516407 |
| 26 | Pancreatic cysts (HP:0001737) | 2.86423294 |
| 27 | Reticulocytopenia (HP:0001896) | 2.86406615 |
| 28 | Macrocytic anemia (HP:0001972) | 2.72708346 |
| 29 | Nephronophthisis (HP:0000090) | 2.66931899 |
| 30 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.62093329 |
| 31 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.62093329 |
| 32 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.57566268 |
| 33 | Absent/shortened dynein arms (HP:0200106) | 2.57566268 |
| 34 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.57019251 |
| 35 | Abnormality of urine glucose concentration (HP:0011016) | 2.56678551 |
| 36 | Glycosuria (HP:0003076) | 2.56678551 |
| 37 | Colon cancer (HP:0003003) | 2.52616449 |
| 38 | Abnormality of the labia minora (HP:0012880) | 2.52592623 |
| 39 | Pancreatic fibrosis (HP:0100732) | 2.46077954 |
| 40 | Increased serum lactate (HP:0002151) | 2.43406432 |
| 41 | Increased intramyocellular lipid droplets (HP:0012240) | 2.42529261 |
| 42 | Retinal dysplasia (HP:0007973) | 2.38526003 |
| 43 | Lissencephaly (HP:0001339) | 2.35795653 |
| 44 | Congenital stationary night blindness (HP:0007642) | 2.34998263 |
| 45 | Abnormal ciliary motility (HP:0012262) | 2.34178263 |
| 46 | Chronic hepatic failure (HP:0100626) | 2.33071518 |
| 47 | True hermaphroditism (HP:0010459) | 2.32207320 |
| 48 | Optic disc pallor (HP:0000543) | 2.31076975 |
| 49 | Abnormality of the renal cortex (HP:0011035) | 2.30269817 |
| 50 | Lactic acidosis (HP:0003128) | 2.23336161 |
| 51 | Hyperglycinemia (HP:0002154) | 2.17122427 |
| 52 | Pachygyria (HP:0001302) | 2.14265054 |
| 53 | Absent thumb (HP:0009777) | 2.13926798 |
| 54 | Respiratory failure (HP:0002878) | 2.11342079 |
| 55 | Abnormality of renal resorption (HP:0011038) | 2.10240160 |
| 56 | Abnormality of the renal medulla (HP:0100957) | 2.06676259 |
| 57 | Myokymia (HP:0002411) | 2.04694199 |
| 58 | Pendular nystagmus (HP:0012043) | 2.02942131 |
| 59 | Tubular atrophy (HP:0000092) | 2.02629059 |
| 60 | Pallor (HP:0000980) | 2.01964998 |
| 61 | Abnormal pupillary function (HP:0007686) | 2.00817794 |
| 62 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.99513024 |
| 63 | Methylmalonic acidemia (HP:0002912) | 1.99334847 |
| 64 | Renal cortical cysts (HP:0000803) | 1.98131025 |
| 65 | Leukodystrophy (HP:0002415) | 1.97988659 |
| 66 | Methylmalonic aciduria (HP:0012120) | 1.97318282 |
| 67 | Gait imbalance (HP:0002141) | 1.94493164 |
| 68 | Sclerocornea (HP:0000647) | 1.93921393 |
| 69 | Lethargy (HP:0001254) | 1.93145433 |
| 70 | Polyphagia (HP:0002591) | 1.92580132 |
| 71 | Rib fusion (HP:0000902) | 1.92457185 |
| 72 | Narrow forehead (HP:0000341) | 1.92350203 |
| 73 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.91649255 |
| 74 | Abnormality of the corticospinal tract (HP:0002492) | 1.90672053 |
| 75 | Focal motor seizures (HP:0011153) | 1.90093754 |
| 76 | Anophthalmia (HP:0000528) | 1.89099860 |
| 77 | Increased muscle lipid content (HP:0009058) | 1.88979825 |
| 78 | Hyperphosphaturia (HP:0003109) | 1.83983563 |
| 79 | Abnormal drinking behavior (HP:0030082) | 1.83421604 |
| 80 | Polydipsia (HP:0001959) | 1.83421604 |
| 81 | Partial agenesis of the corpus callosum (HP:0001338) | 1.82692878 |
| 82 | Abnormal number of incisors (HP:0011064) | 1.82675655 |
| 83 | Exercise intolerance (HP:0003546) | 1.82121821 |
| 84 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.82045103 |
| 85 | X-linked dominant inheritance (HP:0001423) | 1.80754710 |
| 86 | Type 2 muscle fiber atrophy (HP:0003554) | 1.77259270 |
| 87 | Ectopic kidney (HP:0000086) | 1.74292825 |
| 88 | Emotional lability (HP:0000712) | 1.72136776 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.71949504 |
| 90 | Hyperalaninemia (HP:0003348) | 1.71949504 |
| 91 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.71949504 |
| 92 | Generalized aminoaciduria (HP:0002909) | 1.71061066 |
| 93 | Nephrogenic diabetes insipidus (HP:0009806) | 1.70943600 |
| 94 | Volvulus (HP:0002580) | 1.69614946 |
| 95 | Abolished electroretinogram (ERG) (HP:0000550) | 1.69212187 |
| 96 | Abnormality of the 4th metacarpal (HP:0010012) | 1.68966518 |
| 97 | Rhinitis (HP:0012384) | 1.65677222 |
| 98 | Delayed CNS myelination (HP:0002188) | 1.65324986 |
| 99 | Opisthotonus (HP:0002179) | 1.63060632 |
| 100 | Congenital, generalized hypertrichosis (HP:0004540) | 1.63046759 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K9 | 3.83408488 |
| 2 | DYRK2 | 3.03747115 |
| 3 | GRK1 | 2.60395849 |
| 4 | MARK1 | 2.58799975 |
| 5 | WNK3 | 2.52595236 |
| 6 | MAP4K2 | 2.45033435 |
| 7 | BUB1 | 2.39833254 |
| 8 | MAPK13 | 2.39757344 |
| 9 | NME1 | 2.36470067 |
| 10 | PINK1 | 2.28386901 |
| 11 | NUAK1 | 2.18797578 |
| 12 | ADRBK2 | 2.10353251 |
| 13 | STK16 | 1.98786917 |
| 14 | CAMKK2 | 1.89401804 |
| 15 | VRK2 | 1.80812340 |
| 16 | WNK4 | 1.74267722 |
| 17 | CDK19 | 1.71004062 |
| 18 | LIMK1 | 1.59209239 |
| 19 | TNIK | 1.58229213 |
| 20 | PNCK | 1.50927459 |
| 21 | NME2 | 1.47463129 |
| 22 | EPHB2 | 1.47161986 |
| 23 | PHKG1 | 1.36651469 |
| 24 | PHKG2 | 1.36651469 |
| 25 | TLK1 | 1.35509172 |
| 26 | OXSR1 | 1.34244053 |
| 27 | TIE1 | 1.29564684 |
| 28 | VRK1 | 1.28826968 |
| 29 | ZAK | 1.28214831 |
| 30 | TXK | 1.25233627 |
| 31 | BCKDK | 1.24260881 |
| 32 | MINK1 | 1.23429768 |
| 33 | CASK | 1.21117253 |
| 34 | TAOK3 | 1.20838428 |
| 35 | EPHA4 | 1.20283937 |
| 36 | BRAF | 1.17429157 |
| 37 | SRPK1 | 1.16246899 |
| 38 | WEE1 | 1.13965611 |
| 39 | FRK | 1.13416807 |
| 40 | CSNK1G2 | 1.06888862 |
| 41 | CDC7 | 1.06083806 |
| 42 | INSRR | 1.03828503 |
| 43 | STK39 | 1.02807409 |
| 44 | PRKCG | 1.02672086 |
| 45 | NEK1 | 0.99397138 |
| 46 | DYRK3 | 0.99012840 |
| 47 | CSNK1G3 | 0.96095383 |
| 48 | AURKA | 0.95900115 |
| 49 | CAMK1 | 0.93164408 |
| 50 | NTRK2 | 0.92037686 |
| 51 | MAP3K12 | 0.90951701 |
| 52 | PRKCH | 0.89473030 |
| 53 | PRKCI | 0.83981765 |
| 54 | CAMKK1 | 0.77015542 |
| 55 | PLK1 | 0.75232058 |
| 56 | MAP2K2 | 0.74663733 |
| 57 | MAP2K7 | 0.74170312 |
| 58 | ABL2 | 0.72736893 |
| 59 | AURKB | 0.72316379 |
| 60 | TRIM28 | 0.72235766 |
| 61 | MUSK | 0.71221502 |
| 62 | MAPKAPK5 | 0.70112602 |
| 63 | CSNK1G1 | 0.69018354 |
| 64 | PLK4 | 0.67244246 |
| 65 | BMPR1B | 0.66108273 |
| 66 | CSNK1A1L | 0.65558074 |
| 67 | TEC | 0.65403702 |
| 68 | CHEK2 | 0.64709841 |
| 69 | ARAF | 0.62528271 |
| 70 | MAP3K11 | 0.60329258 |
| 71 | PAK3 | 0.57152892 |
| 72 | ATR | 0.56542994 |
| 73 | CSNK1E | 0.55608072 |
| 74 | CAMK4 | 0.55057529 |
| 75 | PRKACA | 0.55002812 |
| 76 | PRKCQ | 0.54590815 |
| 77 | PRKCE | 0.54331808 |
| 78 | DYRK1A | 0.53023665 |
| 79 | RPS6KA5 | 0.52356744 |
| 80 | GRK5 | 0.51860697 |
| 81 | ADRBK1 | 0.51496653 |
| 82 | CAMK2A | 0.50503616 |
| 83 | MATK | 0.50257502 |
| 84 | CSNK2A2 | 0.49883761 |
| 85 | PIK3CA | 0.48730387 |
| 86 | CSNK2A1 | 0.47321326 |
| 87 | PKN1 | 0.44848718 |
| 88 | TYRO3 | 0.44241108 |
| 89 | CDK14 | 0.41751889 |
| 90 | CAMK1D | 0.41355743 |
| 91 | MAP2K6 | 0.37787362 |
| 92 | SYK | 0.37010584 |
| 93 | CAMK2D | 0.36889662 |
| 94 | LRRK2 | 0.36806588 |
| 95 | PRKCA | 0.35465111 |
| 96 | CSNK1A1 | 0.34460116 |
| 97 | EIF2AK1 | 0.34234109 |
| 98 | OBSCN | 0.33731109 |
| 99 | PLK3 | 0.33695196 |
| 100 | STK11 | 0.32296910 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.65946881 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.49242496 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.85924347 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.66899941 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.59154107 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.49885047 |
| 7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.37870438 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.16828371 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.04083485 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 1.85049904 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.79525153 |
| 12 | Proteasome_Homo sapiens_hsa03050 | 1.73624275 |
| 13 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.70789787 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.68879545 |
| 15 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.65648549 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.64834066 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.64364184 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.61828857 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.61410950 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59536553 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.55310246 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.52517644 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.50909764 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.49480397 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.47637895 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.46579765 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.44389177 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.35401580 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.30661859 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.15935406 |
| 31 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.07230182 |
| 32 | Purine metabolism_Homo sapiens_hsa00230 | 1.04491333 |
| 33 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03392428 |
| 34 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02649956 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.02308300 |
| 36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.99166483 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99111805 |
| 38 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.97201712 |
| 39 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.96778755 |
| 40 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96299643 |
| 41 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.93063755 |
| 42 | Morphine addiction_Homo sapiens_hsa05032 | 0.91900606 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.91277612 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 0.91196624 |
| 45 | Retinol metabolism_Homo sapiens_hsa00830 | 0.90276621 |
| 46 | Sulfur relay system_Homo sapiens_hsa04122 | 0.89749071 |
| 47 | Histidine metabolism_Homo sapiens_hsa00340 | 0.89184449 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87507479 |
| 49 | Metabolic pathways_Homo sapiens_hsa01100 | 0.87021147 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.84839507 |
| 51 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.84434245 |
| 52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.84086801 |
| 53 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.81630057 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81443205 |
| 55 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.80463483 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.79918844 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.79673395 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78820865 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75868350 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.75153832 |
| 61 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.69566640 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69537404 |
| 63 | Insulin secretion_Homo sapiens_hsa04911 | 0.69459161 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.68403251 |
| 65 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.68229316 |
| 66 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.67655196 |
| 67 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.67545347 |
| 68 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.67062503 |
| 69 | Cocaine addiction_Homo sapiens_hsa05030 | 0.65996305 |
| 70 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65644797 |
| 71 | Olfactory transduction_Homo sapiens_hsa04740 | 0.65527714 |
| 72 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.65202040 |
| 73 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.64629157 |
| 74 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.61288690 |
| 75 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61212574 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59361762 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.58957979 |
| 78 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.58073535 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.57708996 |
| 80 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.57560920 |
| 81 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.57256645 |
| 82 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.53627736 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52900699 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.50664029 |
| 85 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.50535650 |
| 86 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.50449076 |
| 87 | GABAergic synapse_Homo sapiens_hsa04727 | 0.50399282 |
| 88 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.48479112 |
| 89 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.46739433 |
| 90 | Asthma_Homo sapiens_hsa05310 | 0.46574873 |
| 91 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.45951676 |
| 92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44446127 |
| 93 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.44308807 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42812871 |
| 95 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41179454 |
| 96 | Circadian entrainment_Homo sapiens_hsa04713 | 0.41102791 |
| 97 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.39957029 |
| 98 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.37075388 |
| 99 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35277885 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33782138 |

