RPS10P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1energy coupled proton transport, down electrochemical gradient (GO:0015985)6.16493647
2ATP synthesis coupled proton transport (GO:0015986)6.16493647
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.09398727
4ribosomal small subunit assembly (GO:0000028)5.56902025
5chaperone-mediated protein transport (GO:0072321)5.23626004
6ribosomal small subunit biogenesis (GO:0042274)5.20008270
7viral transcription (GO:0019083)4.92323383
8translational termination (GO:0006415)4.72239972
9mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.67415676
10behavioral response to nicotine (GO:0035095)4.67365113
11platelet dense granule organization (GO:0060155)4.63389832
12water-soluble vitamin biosynthetic process (GO:0042364)4.47313788
13respiratory electron transport chain (GO:0022904)4.33630311
14electron transport chain (GO:0022900)4.29021245
15translational elongation (GO:0006414)4.13773727
16SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.05896478
17cotranslational protein targeting to membrane (GO:0006613)4.03406140
18mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.02424417
19mitochondrial respiratory chain complex I assembly (GO:0032981)4.02424417
20NADH dehydrogenase complex assembly (GO:0010257)4.02424417
21protein complex biogenesis (GO:0070271)4.01314003
22protein targeting to ER (GO:0045047)4.01292863
23maturation of SSU-rRNA (GO:0030490)3.89778437
24establishment of protein localization to endoplasmic reticulum (GO:0072599)3.87431926
25establishment of protein localization to mitochondrial membrane (GO:0090151)3.84255684
26protein localization to endoplasmic reticulum (GO:0070972)3.80203172
27mitochondrial respiratory chain complex assembly (GO:0033108)3.77304731
28viral life cycle (GO:0019058)3.67237672
29cellular protein complex disassembly (GO:0043624)3.65631953
30ATP biosynthetic process (GO:0006754)3.64285615
31purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.62809357
32purine nucleoside triphosphate biosynthetic process (GO:0009145)3.58950233
33GTP biosynthetic process (GO:0006183)3.58134542
34indolalkylamine metabolic process (GO:0006586)3.50717926
35opioid receptor signaling pathway (GO:0038003)3.47308399
36nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.42528249
37ribosomal large subunit biogenesis (GO:0042273)3.34943924
38translational initiation (GO:0006413)3.28411307
39protein-cofactor linkage (GO:0018065)3.23624297
40epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.23370099
41DNA deamination (GO:0045006)3.21791810
42alkaloid metabolic process (GO:0009820)3.20652841
43hydrogen ion transmembrane transport (GO:1902600)3.20118748
44ribonucleoside triphosphate biosynthetic process (GO:0009201)3.18958728
45UTP biosynthetic process (GO:0006228)3.18048363
46translation (GO:0006412)3.16999972
47pseudouridine synthesis (GO:0001522)3.16271843
48protein neddylation (GO:0045116)3.13787083
49UTP metabolic process (GO:0046051)3.09639362
50cellular component biogenesis (GO:0044085)3.08262241
51serotonin metabolic process (GO:0042428)3.08018739
52exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.03891789
53nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.03436765
54transcription elongation from RNA polymerase III promoter (GO:0006385)3.03386826
55termination of RNA polymerase III transcription (GO:0006386)3.03386826
56tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.01934842
57RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.01934842
58postsynaptic membrane organization (GO:0001941)3.00815237
59regulation of mitotic spindle checkpoint (GO:1903504)2.99732359
60regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.99732359
61protein complex disassembly (GO:0043241)2.98455472
62primary amino compound metabolic process (GO:1901160)2.94377741
63hydrogen transport (GO:0006818)2.93484287
64proton transport (GO:0015992)2.93273106
65pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.93091734
66macromolecular complex disassembly (GO:0032984)2.89218497
67ribonucleoprotein complex biogenesis (GO:0022613)2.88336883
68L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.84767144
69phosphorylated carbohydrate dephosphorylation (GO:0046838)2.82413763
70inositol phosphate dephosphorylation (GO:0046855)2.82413763
71epithelial cilium movement (GO:0003351)2.81017381
72nucleoside triphosphate biosynthetic process (GO:0009142)2.80646648
73inositol phosphate catabolic process (GO:0071545)2.78960058
74respiratory chain complex IV assembly (GO:0008535)2.74941732
75chromatin remodeling at centromere (GO:0031055)2.72909724
76regulation of action potential (GO:0098900)2.66372489
77positive regulation of prostaglandin secretion (GO:0032308)2.65156518
78rRNA processing (GO:0006364)2.61874967
79protein deneddylation (GO:0000338)2.60966153
80pyrimidine nucleotide catabolic process (GO:0006244)2.60149665
81rRNA metabolic process (GO:0016072)2.59734944
82cullin deneddylation (GO:0010388)2.58993106
83response to pheromone (GO:0019236)2.58819274
84cornea development in camera-type eye (GO:0061303)2.57352991
85protein targeting to mitochondrion (GO:0006626)2.56784629
86nuclear-transcribed mRNA catabolic process (GO:0000956)2.55691629
87pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.55416397
88establishment of protein localization to mitochondrion (GO:0072655)2.54894040
89neuron fate determination (GO:0048664)2.54842918
90behavioral response to ethanol (GO:0048149)2.54108839
91cell proliferation in forebrain (GO:0021846)2.54044251
92replication fork processing (GO:0031297)2.52943166
93protein polyglutamylation (GO:0018095)2.52898847
94anterograde synaptic vesicle transport (GO:0048490)2.52343099
95protein targeting to membrane (GO:0006612)2.49962822
96indole-containing compound metabolic process (GO:0042430)2.49086375
97regulation of prostaglandin secretion (GO:0032306)2.48399434
98negative regulation of transcription regulatory region DNA binding (GO:2000678)2.47815084
99rhodopsin mediated signaling pathway (GO:0016056)2.47739599
100tRNA processing (GO:0008033)2.47158281

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.15098569
2VDR_22108803_ChIP-Seq_LS180_Human3.63386642
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.35114000
4IGF1R_20145208_ChIP-Seq_DFB_Human3.00568083
5HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.98876134
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.96237193
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.90965811
8ZNF274_21170338_ChIP-Seq_K562_Hela2.82464722
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.82060428
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.74861496
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.36208286
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.34042296
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.04196282
14CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88362541
15GBX2_23144817_ChIP-Seq_PC3_Human1.82661260
16GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.80985626
17MYC_18940864_ChIP-ChIP_HL60_Human1.79911224
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79611254
19VDR_23849224_ChIP-Seq_CD4+_Human1.78343621
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73091863
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.67379997
22MYC_18555785_ChIP-Seq_MESCs_Mouse1.65706974
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.64517837
24FUS_26573619_Chip-Seq_HEK293_Human1.63673094
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.61347634
26NOTCH1_21737748_ChIP-Seq_TLL_Human1.59736597
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.59640713
28FOXP3_21729870_ChIP-Seq_TREG_Human1.58281171
29TP63_19390658_ChIP-ChIP_HaCaT_Human1.51642530
30MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.50026016
31HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.49403418
32EWS_26573619_Chip-Seq_HEK293_Human1.48663504
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.47915248
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.41376730
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.40550723
36TP53_22573176_ChIP-Seq_HFKS_Human1.38782581
37SRF_21415370_ChIP-Seq_HL-1_Mouse1.35604704
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34051044
39REST_21632747_ChIP-Seq_MESCs_Mouse1.31339907
40ELK1_19687146_ChIP-ChIP_HELA_Human1.30165173
41IRF1_19129219_ChIP-ChIP_H3396_Human1.29538399
42RBPJ_22232070_ChIP-Seq_NCS_Mouse1.28843741
43EZH2_27304074_Chip-Seq_ESCs_Mouse1.27101132
44P300_19829295_ChIP-Seq_ESCs_Human1.26925953
45FLI1_27457419_Chip-Seq_LIVER_Mouse1.24325003
46JARID2_20064375_ChIP-Seq_MESCs_Mouse1.24280422
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.19886293
48AUTS2_25519132_ChIP-Seq_293T-REX_Human1.17970096
49FOXA1_27270436_Chip-Seq_PROSTATE_Human1.17372627
50FOXA1_25329375_ChIP-Seq_VCAP_Human1.17372627
51POU5F1_16153702_ChIP-ChIP_HESCs_Human1.16303152
52RNF2_27304074_Chip-Seq_NSC_Mouse1.15470302
53HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.15297580
54THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15125515
55ERA_21632823_ChIP-Seq_H3396_Human1.12888863
56SOX2_19829295_ChIP-Seq_ESCs_Human1.12355224
57NANOG_19829295_ChIP-Seq_ESCs_Human1.12355224
58GATA3_21878914_ChIP-Seq_MCF-7_Human1.12235244
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.12187474
60GABP_19822575_ChIP-Seq_HepG2_Human1.12132094
61NCOR_22424771_ChIP-Seq_293T_Human1.10745056
62EED_16625203_ChIP-ChIP_MESCs_Mouse1.10336188
63TTF2_22483619_ChIP-Seq_HELA_Human1.10324273
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09608248
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08421201
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08245508
67PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08004949
68CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.06621327
69GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06459451
70EZH2_27294783_Chip-Seq_ESCs_Mouse1.05454426
71REST_18959480_ChIP-ChIP_MESCs_Mouse1.04488829
72FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03322519
73MYC_18358816_ChIP-ChIP_MESCs_Mouse1.01080761
74TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98412829
75YY1_21170310_ChIP-Seq_MESCs_Mouse0.97613609
76E2F4_17652178_ChIP-ChIP_JURKAT_Human0.97574333
77AR_20517297_ChIP-Seq_VCAP_Human0.95343843
78MYC_19829295_ChIP-Seq_ESCs_Human0.94808127
79SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.94483324
80HTT_18923047_ChIP-ChIP_STHdh_Human0.94155742
81NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.93886709
82AR_21572438_ChIP-Seq_LNCaP_Human0.92915474
83ER_23166858_ChIP-Seq_MCF-7_Human0.92669509
84CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.92360336
85ELF1_17652178_ChIP-ChIP_JURKAT_Human0.92240679
86XRN2_22483619_ChIP-Seq_HELA_Human0.91865210
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90757822
88TCF4_22108803_ChIP-Seq_LS180_Human0.90600182
89FOXH1_21741376_ChIP-Seq_EPCs_Human0.89454852
90SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.89278975
91JARID2_20075857_ChIP-Seq_MESCs_Mouse0.88616826
92SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.87857052
93PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.86698575
94TAF2_19829295_ChIP-Seq_ESCs_Human0.86435062
95EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.85641273
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.84824780
97CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.84584441
98SOX2_18555785_ChIP-Seq_MESCs_Mouse0.84021163
99RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.83294269
100SUZ12_27294783_Chip-Seq_ESCs_Mouse0.82135874

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.30910768
2MP0009379_abnormal_foot_pigmentation4.25310353
3MP0003011_delayed_dark_adaptation3.65709935
4MP0008877_abnormal_DNA_methylation2.81362072
5MP0003122_maternal_imprinting2.67309668
6MP0002638_abnormal_pupillary_reflex2.66650152
7MP0005083_abnormal_biliary_tract2.65247878
8MP0003787_abnormal_imprinting2.54379787
9MP0001529_abnormal_vocalization2.53496344
10MP0005084_abnormal_gallbladder_morpholo2.37310393
11MP0006072_abnormal_retinal_apoptosis2.25066862
12MP0003121_genomic_imprinting2.23089801
13MP0002163_abnormal_gland_morphology2.10983373
14MP0002160_abnormal_reproductive_system2.09790233
15MP0005551_abnormal_eye_electrophysiolog1.97187350
16MP0005379_endocrine/exocrine_gland_phen1.89223758
17MP0005645_abnormal_hypothalamus_physiol1.87397977
18MP0004142_abnormal_muscle_tone1.86652833
19MP0001919_abnormal_reproductive_system1.84413640
20MP0008789_abnormal_olfactory_epithelium1.76942466
21MP0005389_reproductive_system_phenotype1.72314164
22MP0009046_muscle_twitch1.69489718
23MP0000778_abnormal_nervous_system1.64354908
24MP0000569_abnormal_digit_pigmentation1.58424796
25MP0005253_abnormal_eye_physiology1.58315721
26MP0001968_abnormal_touch/_nociception1.56721656
27MP0002102_abnormal_ear_morphology1.56656121
28MP0005394_taste/olfaction_phenotype1.56355452
29MP0005499_abnormal_olfactory_system1.56355452
30MP0005085_abnormal_gallbladder_physiolo1.55965140
31MP0002272_abnormal_nervous_system1.54428451
32MP0009745_abnormal_behavioral_response1.52524381
33MP0003123_paternal_imprinting1.52390632
34MP0006276_abnormal_autonomic_nervous1.50437682
35MP0005075_abnormal_melanosome_morpholog1.48445364
36MP0003646_muscle_fatigue1.47005776
37MP0003880_abnormal_central_pattern1.46016018
38MP0002837_dystrophic_cardiac_calcinosis1.42956410
39MP0002184_abnormal_innervation1.40265696
40MP0001293_anophthalmia1.39308775
41MP0002234_abnormal_pharynx_morphology1.35863735
42MP0000631_abnormal_neuroendocrine_gland1.34190415
43MP0001905_abnormal_dopamine_level1.32429840
44MP0001764_abnormal_homeostasis1.30293984
45MP0005646_abnormal_pituitary_gland1.27862657
46MP0008872_abnormal_physiological_respon1.27526189
47MP0004147_increased_porphyrin_level1.26884344
48MP0002572_abnormal_emotion/affect_behav1.25990347
49MP0002736_abnormal_nociception_after1.23233614
50MP0002876_abnormal_thyroid_physiology1.22918472
51MP0002938_white_spotting1.22697340
52MP0003195_calcinosis1.22689940
53MP0005365_abnormal_bile_salt1.20065869
54MP0005377_hearing/vestibular/ear_phenot1.18213061
55MP0003878_abnormal_ear_physiology1.18213061
56MP0002733_abnormal_thermal_nociception1.17349530
57MP0003806_abnormal_nucleotide_metabolis1.17100786
58MP0008875_abnormal_xenobiotic_pharmacok1.16604821
59MP0005423_abnormal_somatic_nervous1.13475662
60MP0001440_abnormal_grooming_behavior1.13214762
61MP0002557_abnormal_social/conspecific_i1.11703894
62MP0005195_abnormal_posterior_eye1.11277654
63MP0003635_abnormal_synaptic_transmissio1.10055099
64MP0002064_seizures1.08970682
65MP0003693_abnormal_embryo_hatching1.08275556
66MP0001485_abnormal_pinna_reflex1.07911078
67MP0000372_irregular_coat_pigmentation1.07793666
68MP0001970_abnormal_pain_threshold1.06163782
69MP0000049_abnormal_middle_ear1.05471418
70MP0002735_abnormal_chemical_nociception1.04837190
71MP0001984_abnormal_olfaction1.04717837
72MP0004742_abnormal_vestibular_system1.02859549
73MP0002752_abnormal_somatic_nervous1.01449037
74MP0004145_abnormal_muscle_electrophysio1.00714361
75MP0002653_abnormal_ependyma_morphology0.95781985
76MP0004885_abnormal_endolymph0.95398638
77MP0002063_abnormal_learning/memory/cond0.93101188
78MP0005386_behavior/neurological_phenoty0.92975283
79MP0004924_abnormal_behavior0.92975283
80MP0001502_abnormal_circadian_rhythm0.92153442
81MP0004043_abnormal_pH_regulation0.91445833
82MP0001486_abnormal_startle_reflex0.91228038
83MP0005174_abnormal_tail_pigmentation0.88725451
84MP0008058_abnormal_DNA_repair0.88449160
85MP0010030_abnormal_orbit_morphology0.87849504
86MP0004133_heterotaxia0.87845268
87MP0005391_vision/eye_phenotype0.84625544
88MP0001188_hyperpigmentation0.83071410
89MP0004859_abnormal_synaptic_plasticity0.82926449
90MP0002067_abnormal_sensory_capabilities0.82447761
91MP0002095_abnormal_skin_pigmentation0.81323723
92MP0000955_abnormal_spinal_cord0.79506734
93MP0003718_maternal_effect0.75674711
94MP0010386_abnormal_urinary_bladder0.75264136
95MP0002734_abnormal_mechanical_nocicepti0.74335100
96MP0003283_abnormal_digestive_organ0.73872351
97MP0003938_abnormal_ear_development0.73825623
98MP0000026_abnormal_inner_ear0.73783457
99MP0003698_abnormal_male_reproductive0.72971888
100MP0002210_abnormal_sex_determination0.71541593

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.77013497
2Limb dystonia (HP:0002451)4.41471532
3Abnormal mitochondria in muscle tissue (HP:0008316)4.20975164
4Mitochondrial inheritance (HP:0001427)4.18223623
5Acute encephalopathy (HP:0006846)3.99406464
6Progressive macrocephaly (HP:0004481)3.96110967
7Abnormality of cells of the erythroid lineage (HP:0012130)3.82083649
8Increased CSF lactate (HP:0002490)3.81104706
9Molar tooth sign on MRI (HP:0002419)3.66175506
10Abnormality of midbrain morphology (HP:0002418)3.66175506
11Increased hepatocellular lipid droplets (HP:0006565)3.42637644
12Abnormal number of erythroid precursors (HP:0012131)3.42544859
13Renal Fanconi syndrome (HP:0001994)3.32352419
14Hepatocellular necrosis (HP:0001404)3.28444271
15Hypothermia (HP:0002045)3.27148810
16Hepatic necrosis (HP:0002605)3.20714112
17Exertional dyspnea (HP:0002875)3.13644797
183-Methylglutaconic aciduria (HP:0003535)3.11018583
19Lipid accumulation in hepatocytes (HP:0006561)3.09864493
20Limb hypertonia (HP:0002509)3.01073290
21Type II lissencephaly (HP:0007260)2.95177934
22Medial flaring of the eyebrow (HP:0010747)2.95137505
23Decreased activity of mitochondrial respiratory chain (HP:0008972)2.89956333
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.89956333
25Cerebral edema (HP:0002181)2.89516407
26Pancreatic cysts (HP:0001737)2.86423294
27Reticulocytopenia (HP:0001896)2.86406615
28Macrocytic anemia (HP:0001972)2.72708346
29Nephronophthisis (HP:0000090)2.66931899
30Abnormal respiratory epithelium morphology (HP:0012253)2.62093329
31Abnormal respiratory motile cilium morphology (HP:0005938)2.62093329
32Dynein arm defect of respiratory motile cilia (HP:0012255)2.57566268
33Absent/shortened dynein arms (HP:0200106)2.57566268
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.57019251
35Abnormality of urine glucose concentration (HP:0011016)2.56678551
36Glycosuria (HP:0003076)2.56678551
37Colon cancer (HP:0003003)2.52616449
38Abnormality of the labia minora (HP:0012880)2.52592623
39Pancreatic fibrosis (HP:0100732)2.46077954
40Increased serum lactate (HP:0002151)2.43406432
41Increased intramyocellular lipid droplets (HP:0012240)2.42529261
42Retinal dysplasia (HP:0007973)2.38526003
43Lissencephaly (HP:0001339)2.35795653
44Congenital stationary night blindness (HP:0007642)2.34998263
45Abnormal ciliary motility (HP:0012262)2.34178263
46Chronic hepatic failure (HP:0100626)2.33071518
47True hermaphroditism (HP:0010459)2.32207320
48Optic disc pallor (HP:0000543)2.31076975
49Abnormality of the renal cortex (HP:0011035)2.30269817
50Lactic acidosis (HP:0003128)2.23336161
51Hyperglycinemia (HP:0002154)2.17122427
52Pachygyria (HP:0001302)2.14265054
53Absent thumb (HP:0009777)2.13926798
54Respiratory failure (HP:0002878)2.11342079
55Abnormality of renal resorption (HP:0011038)2.10240160
56Abnormality of the renal medulla (HP:0100957)2.06676259
57Myokymia (HP:0002411)2.04694199
58Pendular nystagmus (HP:0012043)2.02942131
59Tubular atrophy (HP:0000092)2.02629059
60Pallor (HP:0000980)2.01964998
61Abnormal pupillary function (HP:0007686)2.00817794
62Abnormal respiratory motile cilium physiology (HP:0012261)1.99513024
63Methylmalonic acidemia (HP:0002912)1.99334847
64Renal cortical cysts (HP:0000803)1.98131025
65Leukodystrophy (HP:0002415)1.97988659
66Methylmalonic aciduria (HP:0012120)1.97318282
67Gait imbalance (HP:0002141)1.94493164
68Sclerocornea (HP:0000647)1.93921393
69Lethargy (HP:0001254)1.93145433
70Polyphagia (HP:0002591)1.92580132
71Rib fusion (HP:0000902)1.92457185
72Narrow forehead (HP:0000341)1.92350203
73Absent rod-and cone-mediated responses on ERG (HP:0007688)1.91649255
74Abnormality of the corticospinal tract (HP:0002492)1.90672053
75Focal motor seizures (HP:0011153)1.90093754
76Anophthalmia (HP:0000528)1.89099860
77Increased muscle lipid content (HP:0009058)1.88979825
78Hyperphosphaturia (HP:0003109)1.83983563
79Abnormal drinking behavior (HP:0030082)1.83421604
80Polydipsia (HP:0001959)1.83421604
81Partial agenesis of the corpus callosum (HP:0001338)1.82692878
82Abnormal number of incisors (HP:0011064)1.82675655
83Exercise intolerance (HP:0003546)1.82121821
84Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.82045103
85X-linked dominant inheritance (HP:0001423)1.80754710
86Type 2 muscle fiber atrophy (HP:0003554)1.77259270
87Ectopic kidney (HP:0000086)1.74292825
88Emotional lability (HP:0000712)1.72136776
89Abnormality of alanine metabolism (HP:0010916)1.71949504
90Hyperalaninemia (HP:0003348)1.71949504
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.71949504
92Generalized aminoaciduria (HP:0002909)1.71061066
93Nephrogenic diabetes insipidus (HP:0009806)1.70943600
94Volvulus (HP:0002580)1.69614946
95Abolished electroretinogram (ERG) (HP:0000550)1.69212187
96Abnormality of the 4th metacarpal (HP:0010012)1.68966518
97Rhinitis (HP:0012384)1.65677222
98Delayed CNS myelination (HP:0002188)1.65324986
99Opisthotonus (HP:0002179)1.63060632
100Congenital, generalized hypertrichosis (HP:0004540)1.63046759

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K93.83408488
2DYRK23.03747115
3GRK12.60395849
4MARK12.58799975
5WNK32.52595236
6MAP4K22.45033435
7BUB12.39833254
8MAPK132.39757344
9NME12.36470067
10PINK12.28386901
11NUAK12.18797578
12ADRBK22.10353251
13STK161.98786917
14CAMKK21.89401804
15VRK21.80812340
16WNK41.74267722
17CDK191.71004062
18LIMK11.59209239
19TNIK1.58229213
20PNCK1.50927459
21NME21.47463129
22EPHB21.47161986
23PHKG11.36651469
24PHKG21.36651469
25TLK11.35509172
26OXSR11.34244053
27TIE11.29564684
28VRK11.28826968
29ZAK1.28214831
30TXK1.25233627
31BCKDK1.24260881
32MINK11.23429768
33CASK1.21117253
34TAOK31.20838428
35EPHA41.20283937
36BRAF1.17429157
37SRPK11.16246899
38WEE11.13965611
39FRK1.13416807
40CSNK1G21.06888862
41CDC71.06083806
42INSRR1.03828503
43STK391.02807409
44PRKCG1.02672086
45NEK10.99397138
46DYRK30.99012840
47CSNK1G30.96095383
48AURKA0.95900115
49CAMK10.93164408
50NTRK20.92037686
51MAP3K120.90951701
52PRKCH0.89473030
53PRKCI0.83981765
54CAMKK10.77015542
55PLK10.75232058
56MAP2K20.74663733
57MAP2K70.74170312
58ABL20.72736893
59AURKB0.72316379
60TRIM280.72235766
61MUSK0.71221502
62MAPKAPK50.70112602
63CSNK1G10.69018354
64PLK40.67244246
65BMPR1B0.66108273
66CSNK1A1L0.65558074
67TEC0.65403702
68CHEK20.64709841
69ARAF0.62528271
70MAP3K110.60329258
71PAK30.57152892
72ATR0.56542994
73CSNK1E0.55608072
74CAMK40.55057529
75PRKACA0.55002812
76PRKCQ0.54590815
77PRKCE0.54331808
78DYRK1A0.53023665
79RPS6KA50.52356744
80GRK50.51860697
81ADRBK10.51496653
82CAMK2A0.50503616
83MATK0.50257502
84CSNK2A20.49883761
85PIK3CA0.48730387
86CSNK2A10.47321326
87PKN10.44848718
88TYRO30.44241108
89CDK140.41751889
90CAMK1D0.41355743
91MAP2K60.37787362
92SYK0.37010584
93CAMK2D0.36889662
94LRRK20.36806588
95PRKCA0.35465111
96CSNK1A10.34460116
97EIF2AK10.34234109
98OBSCN0.33731109
99PLK30.33695196
100STK110.32296910

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.65946881
2Oxidative phosphorylation_Homo sapiens_hsa001904.49242496
3Parkinsons disease_Homo sapiens_hsa050123.85924347
4Huntingtons disease_Homo sapiens_hsa050162.66899941
5Alzheimers disease_Homo sapiens_hsa050102.59154107
6RNA polymerase_Homo sapiens_hsa030202.49885047
7Cardiac muscle contraction_Homo sapiens_hsa042602.37870438
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.16828371
9Protein export_Homo sapiens_hsa030602.04083485
10Phototransduction_Homo sapiens_hsa047441.85049904
11Linoleic acid metabolism_Homo sapiens_hsa005911.79525153
12Proteasome_Homo sapiens_hsa030501.73624275
13Tryptophan metabolism_Homo sapiens_hsa003801.70789787
14Homologous recombination_Homo sapiens_hsa034401.68879545
15Selenocompound metabolism_Homo sapiens_hsa004501.65648549
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.64834066
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.64364184
18Fanconi anemia pathway_Homo sapiens_hsa034601.61828857
19One carbon pool by folate_Homo sapiens_hsa006701.61410950
20Basal transcription factors_Homo sapiens_hsa030221.59536553
21DNA replication_Homo sapiens_hsa030301.55310246
22Pyrimidine metabolism_Homo sapiens_hsa002401.52517644
23RNA degradation_Homo sapiens_hsa030181.50909764
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.49480397
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.47637895
26Nicotine addiction_Homo sapiens_hsa050331.46579765
27Mismatch repair_Homo sapiens_hsa034301.44389177
28Nucleotide excision repair_Homo sapiens_hsa034201.35401580
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.30661859
30Base excision repair_Homo sapiens_hsa034101.15935406
31Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.07230182
32Purine metabolism_Homo sapiens_hsa002301.04491333
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.03392428
34Butanoate metabolism_Homo sapiens_hsa006501.02649956
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02308300
36Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.99166483
37Nitrogen metabolism_Homo sapiens_hsa009100.99111805
38Propanoate metabolism_Homo sapiens_hsa006400.97201712
39Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96778755
40Ether lipid metabolism_Homo sapiens_hsa005650.96299643
41Primary bile acid biosynthesis_Homo sapiens_hsa001200.93063755
42Morphine addiction_Homo sapiens_hsa050320.91900606
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91277612
44RNA transport_Homo sapiens_hsa030130.91196624
45Retinol metabolism_Homo sapiens_hsa008300.90276621
46Sulfur relay system_Homo sapiens_hsa041220.89749071
47Histidine metabolism_Homo sapiens_hsa003400.89184449
48Caffeine metabolism_Homo sapiens_hsa002320.87507479
49Metabolic pathways_Homo sapiens_hsa011000.87021147
50Chemical carcinogenesis_Homo sapiens_hsa052040.84839507
51Folate biosynthesis_Homo sapiens_hsa007900.84434245
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.84086801
53Fatty acid elongation_Homo sapiens_hsa000620.81630057
54Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81443205
55Phenylalanine metabolism_Homo sapiens_hsa003600.80463483
56Spliceosome_Homo sapiens_hsa030400.79918844
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.79673395
58Arachidonic acid metabolism_Homo sapiens_hsa005900.78820865
59Sulfur metabolism_Homo sapiens_hsa009200.75868350
60Peroxisome_Homo sapiens_hsa041460.75153832
61Fatty acid biosynthesis_Homo sapiens_hsa000610.69566640
62Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.69537404
63Insulin secretion_Homo sapiens_hsa049110.69459161
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68403251
65Steroid biosynthesis_Homo sapiens_hsa001000.68229316
66Maturity onset diabetes of the young_Homo sapiens_hsa049500.67655196
67Tyrosine metabolism_Homo sapiens_hsa003500.67545347
68Collecting duct acid secretion_Homo sapiens_hsa049660.67062503
69Cocaine addiction_Homo sapiens_hsa050300.65996305
70Fat digestion and absorption_Homo sapiens_hsa049750.65644797
71Olfactory transduction_Homo sapiens_hsa047400.65527714
72Non-homologous end-joining_Homo sapiens_hsa034500.65202040
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.64629157
74beta-Alanine metabolism_Homo sapiens_hsa004100.61288690
75Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61212574
76Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.59361762
77Taste transduction_Homo sapiens_hsa047420.58957979
78Serotonergic synapse_Homo sapiens_hsa047260.58073535
79Fatty acid degradation_Homo sapiens_hsa000710.57708996
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.57560920
81Pyruvate metabolism_Homo sapiens_hsa006200.57256645
82Amphetamine addiction_Homo sapiens_hsa050310.53627736
83Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52900699
84Steroid hormone biosynthesis_Homo sapiens_hsa001400.50664029
85Glutathione metabolism_Homo sapiens_hsa004800.50535650
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50449076
87GABAergic synapse_Homo sapiens_hsa047270.50399282
88Dopaminergic synapse_Homo sapiens_hsa047280.48479112
89Basal cell carcinoma_Homo sapiens_hsa052170.46739433
90Asthma_Homo sapiens_hsa053100.46574873
91Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.45951676
92Regulation of autophagy_Homo sapiens_hsa041400.44446127
93Primary immunodeficiency_Homo sapiens_hsa053400.44308807
94Arginine and proline metabolism_Homo sapiens_hsa003300.42812871
95Hedgehog signaling pathway_Homo sapiens_hsa043400.41179454
96Circadian entrainment_Homo sapiens_hsa047130.41102791
97Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.39957029
98Glutamatergic synapse_Homo sapiens_hsa047240.37075388
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.35277885
100Fatty acid metabolism_Homo sapiens_hsa012120.33782138

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »