

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.86041237 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.41335320 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.41335320 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 6.02403463 |
| 5 | viral transcription (GO:0019083) | 5.41144125 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.34965034 |
| 7 | translational termination (GO:0006415) | 5.22636624 |
| 8 | respiratory electron transport chain (GO:0022904) | 5.05226633 |
| 9 | electron transport chain (GO:0022900) | 4.99580455 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.88467589 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 4.81653359 |
| 12 | DNA deamination (GO:0045006) | 4.75086392 |
| 13 | protein targeting to ER (GO:0045047) | 4.74521956 |
| 14 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.56239606 |
| 15 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.54485171 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 4.50872117 |
| 17 | translational elongation (GO:0006414) | 4.48143295 |
| 18 | sequestering of actin monomers (GO:0042989) | 4.18929302 |
| 19 | protein complex biogenesis (GO:0070271) | 3.93921368 |
| 20 | cellular protein complex disassembly (GO:0043624) | 3.92295736 |
| 21 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.91177886 |
| 22 | viral life cycle (GO:0019058) | 3.84297235 |
| 23 | hydrogen ion transmembrane transport (GO:1902600) | 3.77957621 |
| 24 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.70996227 |
| 25 | platelet dense granule organization (GO:0060155) | 3.69036533 |
| 26 | cytidine deamination (GO:0009972) | 3.63843156 |
| 27 | cytidine metabolic process (GO:0046087) | 3.63843156 |
| 28 | cytidine catabolic process (GO:0006216) | 3.63843156 |
| 29 | translational initiation (GO:0006413) | 3.59459455 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.59021058 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 3.59021058 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.59021058 |
| 33 | ATP biosynthetic process (GO:0006754) | 3.58360189 |
| 34 | maturation of SSU-rRNA (GO:0030490) | 3.53851559 |
| 35 | proton transport (GO:0015992) | 3.50530437 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.48849798 |
| 37 | chaperone-mediated protein transport (GO:0072321) | 3.45417229 |
| 38 | hydrogen transport (GO:0006818) | 3.43159078 |
| 39 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.42502862 |
| 40 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.41001378 |
| 41 | protein neddylation (GO:0045116) | 3.40789867 |
| 42 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.40062059 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.40062059 |
| 44 | mannosylation (GO:0097502) | 3.39460338 |
| 45 | proteasome assembly (GO:0043248) | 3.39358476 |
| 46 | ribosomal large subunit biogenesis (GO:0042273) | 3.36106170 |
| 47 | translation (GO:0006412) | 3.35063710 |
| 48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.32718389 |
| 49 | protein complex disassembly (GO:0043241) | 3.22597528 |
| 50 | GPI anchor biosynthetic process (GO:0006506) | 3.20046478 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.19647120 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.17545076 |
| 53 | GPI anchor metabolic process (GO:0006505) | 3.15479534 |
| 54 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.14174325 |
| 55 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.09302502 |
| 56 | protein targeting to membrane (GO:0006612) | 3.08924772 |
| 57 | macromolecular complex disassembly (GO:0032984) | 3.07559620 |
| 58 | cytochrome complex assembly (GO:0017004) | 3.04731331 |
| 59 | behavioral response to nicotine (GO:0035095) | 3.04409223 |
| 60 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.01193062 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 3.01193062 |
| 62 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.98092122 |
| 63 | GTP biosynthetic process (GO:0006183) | 2.92287991 |
| 64 | protein-cofactor linkage (GO:0018065) | 2.91930066 |
| 65 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.91691963 |
| 66 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.90738133 |
| 67 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.88684843 |
| 68 | negative regulation of heart rate (GO:0010459) | 2.87299880 |
| 69 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.86787586 |
| 70 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.86097798 |
| 71 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.83435286 |
| 72 | indole-containing compound catabolic process (GO:0042436) | 2.78623466 |
| 73 | indolalkylamine catabolic process (GO:0046218) | 2.78623466 |
| 74 | tryptophan catabolic process (GO:0006569) | 2.78623466 |
| 75 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.77640840 |
| 76 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.77640840 |
| 77 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.77640840 |
| 78 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.74998536 |
| 79 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.74998536 |
| 80 | cellular ketone body metabolic process (GO:0046950) | 2.73678275 |
| 81 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.73601902 |
| 82 | kynurenine metabolic process (GO:0070189) | 2.71548541 |
| 83 | adult feeding behavior (GO:0008343) | 2.70093986 |
| 84 | mRNA catabolic process (GO:0006402) | 2.67631370 |
| 85 | indolalkylamine metabolic process (GO:0006586) | 2.64633717 |
| 86 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.62096610 |
| 87 | negative regulation of ligase activity (GO:0051352) | 2.62096610 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.59281542 |
| 89 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.59281542 |
| 90 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.59139601 |
| 91 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.55984390 |
| 92 | ribosomal small subunit biogenesis (GO:0042274) | 2.52713994 |
| 93 | aldehyde catabolic process (GO:0046185) | 2.52606993 |
| 94 | spliceosomal complex assembly (GO:0000245) | 2.50375210 |
| 95 | actin nucleation (GO:0045010) | 2.49964432 |
| 96 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.49757675 |
| 97 | dopamine transport (GO:0015872) | 2.49643653 |
| 98 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.48999559 |
| 99 | ketone body metabolic process (GO:1902224) | 2.46170265 |
| 100 | intracellular protein transmembrane import (GO:0044743) | 2.45686349 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.83197160 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.67647167 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.65779637 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.41410931 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.28597932 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01815622 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.95877034 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.84068866 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.82608522 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.81209105 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.38553033 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.19579706 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.18904493 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.18457195 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.10743307 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.08498610 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.08361129 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.06496709 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.04906977 |
| 20 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.98227793 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.97928334 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.86526575 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.80042583 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.75730297 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.70258939 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69807414 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.68807872 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.68648985 |
| 29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.65625660 |
| 30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.64805486 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.61502536 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.61493182 |
| 33 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.60871471 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.49748406 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.48387617 |
| 36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.46008078 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44818024 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.44385905 |
| 39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.44385905 |
| 40 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.44039845 |
| 41 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.42818839 |
| 42 | AR_20517297_ChIP-Seq_VCAP_Human | 1.42563514 |
| 43 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.41586202 |
| 44 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.39156862 |
| 45 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.38799293 |
| 46 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.36508318 |
| 47 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.34621159 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33724119 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28353549 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28353549 |
| 51 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.27223162 |
| 52 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.27164690 |
| 53 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.27164690 |
| 54 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.26425107 |
| 55 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.21478267 |
| 56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19526990 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17468275 |
| 58 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16690280 |
| 59 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16159711 |
| 60 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.15371775 |
| 61 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15097969 |
| 62 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.14193444 |
| 63 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.12868272 |
| 64 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.12363757 |
| 65 | GATA3_26560356_Chip-Seq_TH2_Human | 1.12332120 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11764263 |
| 67 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.10763973 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.10053020 |
| 69 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.09724676 |
| 70 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09553901 |
| 71 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09292671 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.08937355 |
| 73 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.08886109 |
| 74 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.07645959 |
| 75 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07510052 |
| 76 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07318852 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.07114159 |
| 78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.06812757 |
| 79 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.03510743 |
| 80 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.03381413 |
| 81 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.03178591 |
| 82 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02472660 |
| 83 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99621334 |
| 84 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.99485540 |
| 85 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.99371286 |
| 86 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.97410402 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.96861525 |
| 88 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.96711182 |
| 89 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96428182 |
| 90 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95577161 |
| 91 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95423707 |
| 92 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.94715703 |
| 93 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93258945 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.90307645 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88854646 |
| 96 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.87390913 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.86871271 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.86422291 |
| 99 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.86400917 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85393914 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.69525320 |
| 2 | MP0005671_abnormal_response_to | 3.26071369 |
| 3 | MP0006072_abnormal_retinal_apoptosis | 3.25068725 |
| 4 | MP0006292_abnormal_olfactory_placode | 2.94241439 |
| 5 | MP0003283_abnormal_digestive_organ | 2.64606238 |
| 6 | MP0002102_abnormal_ear_morphology | 2.38147597 |
| 7 | MP0008995_early_reproductive_senescence | 2.24867683 |
| 8 | MP0002234_abnormal_pharynx_morphology | 2.20459395 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.18326239 |
| 10 | MP0003880_abnormal_central_pattern | 2.12672614 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 1.95930292 |
| 12 | MP0005253_abnormal_eye_physiology | 1.92262492 |
| 13 | MP0002638_abnormal_pupillary_reflex | 1.91424946 |
| 14 | MP0004147_increased_porphyrin_level | 1.89644303 |
| 15 | MP0002938_white_spotting | 1.84063021 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.79710683 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.78514901 |
| 18 | MP0005551_abnormal_eye_electrophysiolog | 1.76371770 |
| 19 | MP0003195_calcinosis | 1.75236494 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.70725128 |
| 21 | MP0001905_abnormal_dopamine_level | 1.70202789 |
| 22 | MP0008872_abnormal_physiological_respon | 1.63886860 |
| 23 | MP0001529_abnormal_vocalization | 1.63456646 |
| 24 | MP0000566_synostosis | 1.63359593 |
| 25 | MP0005646_abnormal_pituitary_gland | 1.60622641 |
| 26 | MP0004142_abnormal_muscle_tone | 1.59643378 |
| 27 | MP0008877_abnormal_DNA_methylation | 1.58796650 |
| 28 | MP0003787_abnormal_imprinting | 1.51772295 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.48101066 |
| 30 | MP0005075_abnormal_melanosome_morpholog | 1.46791894 |
| 31 | MP0002277_abnormal_respiratory_mucosa | 1.45789073 |
| 32 | MP0004885_abnormal_endolymph | 1.44199305 |
| 33 | MP0002166_altered_tumor_susceptibility | 1.38068290 |
| 34 | MP0003011_delayed_dark_adaptation | 1.36417568 |
| 35 | MP0009785_altered_susceptibility_to | 1.34792499 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.33638494 |
| 37 | MP0002653_abnormal_ependyma_morphology | 1.33502839 |
| 38 | MP0001919_abnormal_reproductive_system | 1.27335974 |
| 39 | MP0000631_abnormal_neuroendocrine_gland | 1.27313919 |
| 40 | MP0003136_yellow_coat_color | 1.27273394 |
| 41 | MP0005389_reproductive_system_phenotype | 1.24044642 |
| 42 | MP0001968_abnormal_touch/_nociception | 1.20364197 |
| 43 | MP0002736_abnormal_nociception_after | 1.19589049 |
| 44 | MP0002006_tumorigenesis | 1.18863738 |
| 45 | MP0001986_abnormal_taste_sensitivity | 1.14191583 |
| 46 | MP0002876_abnormal_thyroid_physiology | 1.13936335 |
| 47 | MP0005085_abnormal_gallbladder_physiolo | 1.13756891 |
| 48 | MP0002138_abnormal_hepatobiliary_system | 1.13701943 |
| 49 | MP0004133_heterotaxia | 1.13155371 |
| 50 | MP0002095_abnormal_skin_pigmentation | 1.11006308 |
| 51 | MP0008789_abnormal_olfactory_epithelium | 1.09802909 |
| 52 | MP0003646_muscle_fatigue | 1.09347663 |
| 53 | MP0003252_abnormal_bile_duct | 1.09058086 |
| 54 | MP0009745_abnormal_behavioral_response | 1.08633674 |
| 55 | MP0003878_abnormal_ear_physiology | 1.05561301 |
| 56 | MP0005377_hearing/vestibular/ear_phenot | 1.05561301 |
| 57 | MP0002272_abnormal_nervous_system | 1.04784357 |
| 58 | MP0003786_premature_aging | 1.04425153 |
| 59 | MP0001984_abnormal_olfaction | 1.03499510 |
| 60 | MP0004742_abnormal_vestibular_system | 1.01518898 |
| 61 | MP0001800_abnormal_humoral_immune | 1.01406369 |
| 62 | MP0003938_abnormal_ear_development | 0.99018995 |
| 63 | MP0001764_abnormal_homeostasis | 0.98561623 |
| 64 | MP0004145_abnormal_muscle_electrophysio | 0.98519634 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 0.97072405 |
| 66 | MP0001873_stomach_inflammation | 0.97037223 |
| 67 | MP0002282_abnormal_trachea_morphology | 0.94872329 |
| 68 | MP0009046_muscle_twitch | 0.94149116 |
| 69 | MP0001293_anophthalmia | 0.94131517 |
| 70 | MP0002148_abnormal_hypersensitivity_rea | 0.94014895 |
| 71 | MP0005000_abnormal_immune_tolerance | 0.92614807 |
| 72 | MP0002160_abnormal_reproductive_system | 0.92199926 |
| 73 | MP0000516_abnormal_urinary_system | 0.91710846 |
| 74 | MP0005367_renal/urinary_system_phenotyp | 0.91710846 |
| 75 | MP0002751_abnormal_autonomic_nervous | 0.91559384 |
| 76 | MP0003122_maternal_imprinting | 0.90530082 |
| 77 | MP0003724_increased_susceptibility_to | 0.89310911 |
| 78 | MP0001485_abnormal_pinna_reflex | 0.88402182 |
| 79 | MP0000569_abnormal_digit_pigmentation | 0.88195784 |
| 80 | MP0005195_abnormal_posterior_eye | 0.87027647 |
| 81 | MP0000383_abnormal_hair_follicle | 0.86183726 |
| 82 | MP0010386_abnormal_urinary_bladder | 0.85252760 |
| 83 | MP0002693_abnormal_pancreas_physiology | 0.85112347 |
| 84 | MP0009333_abnormal_splenocyte_physiolog | 0.85103637 |
| 85 | MP0009764_decreased_sensitivity_to | 0.83217465 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.82324153 |
| 87 | MP0008058_abnormal_DNA_repair | 0.81911027 |
| 88 | MP0002723_abnormal_immune_serum | 0.79499799 |
| 89 | MP0003119_abnormal_digestive_system | 0.79278382 |
| 90 | MP0005410_abnormal_fertilization | 0.79072506 |
| 91 | MP0003718_maternal_effect | 0.79018701 |
| 92 | MP0002557_abnormal_social/conspecific_i | 0.78647177 |
| 93 | MP0000026_abnormal_inner_ear | 0.78646131 |
| 94 | MP0003806_abnormal_nucleotide_metabolis | 0.75158083 |
| 95 | MP0000049_abnormal_middle_ear | 0.74676076 |
| 96 | MP0001970_abnormal_pain_threshold | 0.74477169 |
| 97 | MP0005391_vision/eye_phenotype | 0.71734495 |
| 98 | MP0003121_genomic_imprinting | 0.70804416 |
| 99 | MP0001486_abnormal_startle_reflex | 0.70654405 |
| 100 | MP0002928_abnormal_bile_duct | 0.69611310 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.82817052 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.55807343 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.27514878 |
| 4 | Progressive macrocephaly (HP:0004481) | 4.13927317 |
| 5 | Acute encephalopathy (HP:0006846) | 4.04353079 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.04006349 |
| 7 | Increased CSF lactate (HP:0002490) | 3.95391438 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.91299435 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.71398246 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.71299742 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.51430518 |
| 12 | Hepatic necrosis (HP:0002605) | 3.51192353 |
| 13 | Pancreatic cysts (HP:0001737) | 3.48939879 |
| 14 | Cerebral edema (HP:0002181) | 3.22619572 |
| 15 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.21708337 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.15790544 |
| 17 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.09034696 |
| 18 | Pancreatic fibrosis (HP:0100732) | 3.01019014 |
| 19 | True hermaphroditism (HP:0010459) | 3.00756798 |
| 20 | Abnormal number of erythroid precursors (HP:0012131) | 3.00667078 |
| 21 | Reticulocytopenia (HP:0001896) | 2.97478905 |
| 22 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.94754468 |
| 23 | Molar tooth sign on MRI (HP:0002419) | 2.85963999 |
| 24 | Abnormality of midbrain morphology (HP:0002418) | 2.85963999 |
| 25 | Optic disc pallor (HP:0000543) | 2.84110148 |
| 26 | Congenital stationary night blindness (HP:0007642) | 2.80036474 |
| 27 | Type II lissencephaly (HP:0007260) | 2.75353052 |
| 28 | Hypothermia (HP:0002045) | 2.71007740 |
| 29 | Aplastic anemia (HP:0001915) | 2.69851781 |
| 30 | Methylmalonic acidemia (HP:0002912) | 2.69021312 |
| 31 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.68938786 |
| 32 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.68938786 |
| 33 | Increased intramyocellular lipid droplets (HP:0012240) | 2.68081221 |
| 34 | Macrocytic anemia (HP:0001972) | 2.66713141 |
| 35 | Exertional dyspnea (HP:0002875) | 2.63457024 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.61659147 |
| 37 | IgG deficiency (HP:0004315) | 2.59421776 |
| 38 | Nephronophthisis (HP:0000090) | 2.50339078 |
| 39 | Abolished electroretinogram (ERG) (HP:0000550) | 2.48422870 |
| 40 | Severe combined immunodeficiency (HP:0004430) | 2.40231581 |
| 41 | Attenuation of retinal blood vessels (HP:0007843) | 2.39458269 |
| 42 | Decreased central vision (HP:0007663) | 2.38769351 |
| 43 | Lactic acidosis (HP:0003128) | 2.38729499 |
| 44 | Constricted visual fields (HP:0001133) | 2.35212796 |
| 45 | Increased serum lactate (HP:0002151) | 2.30652231 |
| 46 | Hyperglycinemia (HP:0002154) | 2.27640732 |
| 47 | Lethargy (HP:0001254) | 2.25249327 |
| 48 | Respiratory failure (HP:0002878) | 2.24956945 |
| 49 | Hypoproteinemia (HP:0003075) | 2.21895389 |
| 50 | Thyroiditis (HP:0100646) | 2.20104644 |
| 51 | Increased muscle lipid content (HP:0009058) | 2.19508806 |
| 52 | Pendular nystagmus (HP:0012043) | 2.15927193 |
| 53 | Pallor (HP:0000980) | 2.15041683 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.14020369 |
| 55 | Type I transferrin isoform profile (HP:0003642) | 2.11454911 |
| 56 | Medial flaring of the eyebrow (HP:0010747) | 2.11426169 |
| 57 | Methylmalonic aciduria (HP:0012120) | 2.11354937 |
| 58 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.08733442 |
| 59 | Absent/shortened dynein arms (HP:0200106) | 2.08733442 |
| 60 | Generalized aminoaciduria (HP:0002909) | 2.07972158 |
| 61 | Abnormality of renal resorption (HP:0011038) | 2.07575300 |
| 62 | Leukodystrophy (HP:0002415) | 2.06260127 |
| 63 | Abnormality of the renal medulla (HP:0100957) | 2.05072026 |
| 64 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.04871306 |
| 65 | Keratoconus (HP:0000563) | 2.04682453 |
| 66 | Increased corneal curvature (HP:0100692) | 2.04682453 |
| 67 | Sclerocornea (HP:0000647) | 2.00555185 |
| 68 | Retinal dysplasia (HP:0007973) | 2.00001631 |
| 69 | Cystic liver disease (HP:0006706) | 1.98435027 |
| 70 | Abnormality of urine glucose concentration (HP:0011016) | 1.97587613 |
| 71 | Glycosuria (HP:0003076) | 1.97587613 |
| 72 | Absent thumb (HP:0009777) | 1.93577127 |
| 73 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.91587180 |
| 74 | Exercise intolerance (HP:0003546) | 1.91037718 |
| 75 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.90727230 |
| 76 | Abnormality of the renal cortex (HP:0011035) | 1.90639351 |
| 77 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.87986564 |
| 78 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.86199201 |
| 79 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.86199201 |
| 80 | Concave nail (HP:0001598) | 1.85038286 |
| 81 | Pancytopenia (HP:0001876) | 1.84368855 |
| 82 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.80689355 |
| 83 | Dicarboxylic aciduria (HP:0003215) | 1.80689355 |
| 84 | Abnormality of the prostate (HP:0008775) | 1.80623096 |
| 85 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.79607386 |
| 86 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.78126287 |
| 87 | Respiratory difficulties (HP:0002880) | 1.78012981 |
| 88 | Combined immunodeficiency (HP:0005387) | 1.76373981 |
| 89 | Male pseudohermaphroditism (HP:0000037) | 1.75397588 |
| 90 | Abnormal protein glycosylation (HP:0012346) | 1.75100811 |
| 91 | Abnormal glycosylation (HP:0012345) | 1.75100811 |
| 92 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.75100811 |
| 93 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.75100811 |
| 94 | Cerebellar dysplasia (HP:0007033) | 1.74248238 |
| 95 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.73433583 |
| 96 | CNS demyelination (HP:0007305) | 1.73249194 |
| 97 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.73209536 |
| 98 | Abnormality of alanine metabolism (HP:0010916) | 1.73209536 |
| 99 | Hyperalaninemia (HP:0003348) | 1.73209536 |
| 100 | Abnormal ciliary motility (HP:0012262) | 1.71386200 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.79460282 |
| 2 | MAP4K2 | 3.58266859 |
| 3 | TLK1 | 3.21217566 |
| 4 | CDK19 | 3.17391753 |
| 5 | TXK | 3.04796933 |
| 6 | ZAK | 3.03357982 |
| 7 | FRK | 2.45093877 |
| 8 | TAOK3 | 2.44685886 |
| 9 | NUAK1 | 2.25492478 |
| 10 | BCKDK | 2.21438548 |
| 11 | KDR | 2.19461329 |
| 12 | VRK1 | 2.18885247 |
| 13 | ADRBK2 | 2.16731471 |
| 14 | GRK1 | 2.06412858 |
| 15 | WNK3 | 1.94419940 |
| 16 | TESK2 | 1.80261020 |
| 17 | MAP3K12 | 1.73495699 |
| 18 | BUB1 | 1.71713405 |
| 19 | PASK | 1.65927119 |
| 20 | WNK4 | 1.62053225 |
| 21 | BMPR2 | 1.58133343 |
| 22 | PINK1 | 1.44689551 |
| 23 | ERBB3 | 1.33549135 |
| 24 | KIT | 1.25865195 |
| 25 | BMPR1B | 1.24820033 |
| 26 | INSRR | 1.16272512 |
| 27 | SRPK1 | 1.13687301 |
| 28 | NME1 | 1.07241723 |
| 29 | GRK6 | 1.05599160 |
| 30 | STK16 | 1.05036079 |
| 31 | MAPK13 | 1.03045608 |
| 32 | MYLK | 1.02816843 |
| 33 | DYRK2 | 1.02321652 |
| 34 | SCYL2 | 1.01645166 |
| 35 | TEC | 0.98446544 |
| 36 | MST4 | 0.97690221 |
| 37 | FES | 0.90979304 |
| 38 | CSNK1G3 | 0.90398123 |
| 39 | SYK | 0.89100810 |
| 40 | TAF1 | 0.87171083 |
| 41 | ITK | 0.85961036 |
| 42 | OXSR1 | 0.85229049 |
| 43 | MAP3K4 | 0.80754256 |
| 44 | MUSK | 0.79737277 |
| 45 | IKBKB | 0.79468612 |
| 46 | RPS6KA5 | 0.78744781 |
| 47 | CSNK1G2 | 0.78739139 |
| 48 | LIMK1 | 0.78056634 |
| 49 | FGFR2 | 0.77507628 |
| 50 | DAPK3 | 0.77313885 |
| 51 | MAP2K7 | 0.75675568 |
| 52 | CDK8 | 0.75250255 |
| 53 | PHKG1 | 0.75170052 |
| 54 | PHKG2 | 0.75170052 |
| 55 | FLT3 | 0.74634262 |
| 56 | EPHA4 | 0.74600891 |
| 57 | MKNK1 | 0.73561766 |
| 58 | CSF1R | 0.72822908 |
| 59 | DAPK1 | 0.68623446 |
| 60 | CSNK1G1 | 0.67966975 |
| 61 | MAP4K1 | 0.66893114 |
| 62 | DAPK2 | 0.65957770 |
| 63 | ADRBK1 | 0.65475429 |
| 64 | PRKCE | 0.64601579 |
| 65 | GRK7 | 0.60850664 |
| 66 | LYN | 0.60222510 |
| 67 | OBSCN | 0.60159680 |
| 68 | PRKCQ | 0.59804046 |
| 69 | TRIM28 | 0.58061984 |
| 70 | CSNK1A1L | 0.53835151 |
| 71 | LCK | 0.52339570 |
| 72 | PIK3CG | 0.51810869 |
| 73 | PLK4 | 0.50815115 |
| 74 | ILK | 0.49664045 |
| 75 | PRKCG | 0.49561123 |
| 76 | AURKB | 0.48758236 |
| 77 | TGFBR1 | 0.47542558 |
| 78 | TIE1 | 0.47056764 |
| 79 | NEK2 | 0.46710668 |
| 80 | PRKACA | 0.46546032 |
| 81 | RPS6KA4 | 0.45190437 |
| 82 | PLK3 | 0.43174444 |
| 83 | CCNB1 | 0.42318256 |
| 84 | STK39 | 0.41996925 |
| 85 | GRK5 | 0.41392470 |
| 86 | CSNK2A2 | 0.40302801 |
| 87 | IGF1R | 0.39014148 |
| 88 | IKBKE | 0.37786061 |
| 89 | PLK2 | 0.37609009 |
| 90 | ROCK1 | 0.36962662 |
| 91 | STK38L | 0.36929907 |
| 92 | PIM1 | 0.36492149 |
| 93 | PRKCA | 0.36373458 |
| 94 | CSNK2A1 | 0.35910523 |
| 95 | MAPK15 | 0.35859765 |
| 96 | CAMKK2 | 0.35009940 |
| 97 | CSNK1A1 | 0.34539139 |
| 98 | ATR | 0.34006586 |
| 99 | TNK2 | 0.33712111 |
| 100 | AURKA | 0.32816599 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.49210633 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.21382358 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.68185301 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.38529985 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.93783139 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.59605537 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.46396243 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.41084870 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.35941697 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.33808522 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.31385689 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.25481287 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.19909009 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11731653 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.10172052 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.08499179 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.00806505 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.96332447 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.58533312 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.54008347 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.53835105 |
| 22 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.52525190 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.47352201 |
| 24 | Homologous recombination_Homo sapiens_hsa03440 | 1.43089202 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.33557578 |
| 26 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.23090051 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.22620013 |
| 28 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.21406920 |
| 29 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.19333167 |
| 30 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.19024217 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17429266 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.11054244 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.04082170 |
| 34 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.98465009 |
| 35 | Spliceosome_Homo sapiens_hsa03040 | 0.96653459 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.96612342 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96522591 |
| 38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96398554 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.96226608 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 0.96046633 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 0.95202203 |
| 42 | Mismatch repair_Homo sapiens_hsa03430 | 0.94320384 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.92637720 |
| 44 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90400226 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.88976341 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.88624507 |
| 47 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.84642680 |
| 48 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82758427 |
| 49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.81677745 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.81634992 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.80809145 |
| 52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80761281 |
| 53 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.78286464 |
| 54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.76381540 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.71377858 |
| 56 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.69799246 |
| 57 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69527328 |
| 58 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.67598910 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.66027346 |
| 60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.64691731 |
| 61 | Taste transduction_Homo sapiens_hsa04742 | 0.64271401 |
| 62 | Nicotine addiction_Homo sapiens_hsa05033 | 0.63392198 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63364594 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62536098 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62083980 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.61508045 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.59710463 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.58231229 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.56568923 |
| 70 | Base excision repair_Homo sapiens_hsa03410 | 0.54349649 |
| 71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54003878 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.52716516 |
| 73 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.49821661 |
| 74 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.48995052 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47585634 |
| 76 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43131263 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.42731035 |
| 78 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.42154585 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41436739 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37381919 |
| 81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.34294854 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33933130 |
| 83 | Morphine addiction_Homo sapiens_hsa05032 | 0.33412364 |
| 84 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.33149027 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32829912 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.32724915 |
| 87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32693507 |
| 88 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.32194106 |
| 89 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.31588346 |
| 90 | GABAergic synapse_Homo sapiens_hsa04727 | 0.30735257 |
| 91 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.30302408 |
| 92 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.30123437 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29939034 |
| 94 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.25568087 |
| 95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.22349295 |
| 96 | Salivary secretion_Homo sapiens_hsa04970 | 0.20734487 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.20148989 |
| 98 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.19781792 |
| 99 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.19382728 |
| 100 | Leishmaniasis_Homo sapiens_hsa05140 | 0.19116647 |

