

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | glycoprotein catabolic process (GO:0006516) | 9.96227501 |
| 2 | rRNA transcription (GO:0009303) | 8.53219957 |
| 3 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 8.25470221 |
| 4 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 6.53284120 |
| 5 | induction of positive chemotaxis (GO:0050930) | 6.51716011 |
| 6 | macroautophagy (GO:0016236) | 6.39346548 |
| 7 | meiotic chromosome segregation (GO:0045132) | 6.05593537 |
| 8 | positive regulation of vascular permeability (GO:0043117) | 5.96330850 |
| 9 | resolution of meiotic recombination intermediates (GO:0000712) | 5.92492131 |
| 10 | nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) | 5.73264046 |
| 11 | positive regulation of defense response to virus by host (GO:0002230) | 5.71527988 |
| 12 | viral transcription (GO:0019083) | 5.49250856 |
| 13 | chaperone-mediated protein transport (GO:0072321) | 5.45741899 |
| 14 | myelin assembly (GO:0032288) | 5.45056070 |
| 15 | cellular response to exogenous dsRNA (GO:0071360) | 5.40088598 |
| 16 | translational termination (GO:0006415) | 5.16719287 |
| 17 | DNA deamination (GO:0045006) | 5.01785861 |
| 18 | erythrocyte maturation (GO:0043249) | 5.01202749 |
| 19 | UV protection (GO:0009650) | 4.97401874 |
| 20 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 4.92374875 |
| 21 | reciprocal DNA recombination (GO:0035825) | 4.88011214 |
| 22 | reciprocal meiotic recombination (GO:0007131) | 4.88011214 |
| 23 | positive regulation of monocyte chemotaxis (GO:0090026) | 4.73486782 |
| 24 | I-kappaB kinase/NF-kappaB signaling (GO:0007249) | 4.71403320 |
| 25 | hematopoietic stem cell differentiation (GO:0060218) | 4.64489388 |
| 26 | spinal cord development (GO:0021510) | 4.63430056 |
| 27 | cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) | 4.59896429 |
| 28 | forebrain morphogenesis (GO:0048853) | 4.46833789 |
| 29 | energy homeostasis (GO:0097009) | 4.44749822 |
| 30 | astrocyte differentiation (GO:0048708) | 4.44736538 |
| 31 | hair cell differentiation (GO:0035315) | 4.41293323 |
| 32 | protein targeting to ER (GO:0045047) | 4.12923942 |
| 33 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.11404559 |
| 34 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.09565107 |
| 35 | translational elongation (GO:0006414) | 4.08766264 |
| 36 | cotranslational protein targeting to membrane (GO:0006613) | 4.04358480 |
| 37 | ribosomal small subunit biogenesis (GO:0042274) | 4.03229783 |
| 38 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.93359996 |
| 39 | synaptonemal complex assembly (GO:0007130) | 3.92661462 |
| 40 | viral life cycle (GO:0019058) | 3.83837850 |
| 41 | cellular protein complex disassembly (GO:0043624) | 3.83659116 |
| 42 | protein localization to endoplasmic reticulum (GO:0070972) | 3.78842333 |
| 43 | regulation of lymphocyte migration (GO:2000401) | 3.78316729 |
| 44 | heart morphogenesis (GO:0003007) | 3.67343375 |
| 45 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872) | 3.63862663 |
| 46 | positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) | 3.62201569 |
| 47 | ribosomal small subunit assembly (GO:0000028) | 3.60558600 |
| 48 | positive regulation of positive chemotaxis (GO:0050927) | 3.52264375 |
| 49 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.51765512 |
| 50 | regulation of synapse maturation (GO:0090128) | 3.50235104 |
| 51 | male meiosis I (GO:0007141) | 3.46103176 |
| 52 | synaptonemal complex organization (GO:0070193) | 3.44351539 |
| 53 | lateral ventricle development (GO:0021670) | 3.43512790 |
| 54 | regulation of positive chemotaxis (GO:0050926) | 3.39230136 |
| 55 | maturation of SSU-rRNA (GO:0030490) | 3.36132527 |
| 56 | lymphocyte chemotaxis (GO:0048247) | 3.36079871 |
| 57 | myoblast migration (GO:0051451) | 3.34458267 |
| 58 | pseudouridine synthesis (GO:0001522) | 3.26458964 |
| 59 | JNK cascade (GO:0007254) | 3.25038647 |
| 60 | thrombin receptor signaling pathway (GO:0070493) | 3.24175998 |
| 61 | peroxisome organization (GO:0007031) | 3.21932001 |
| 62 | translational initiation (GO:0006413) | 3.21455062 |
| 63 | protein complex disassembly (GO:0043241) | 3.21408076 |
| 64 | macrophage chemotaxis (GO:0048246) | 3.20115850 |
| 65 | regulation of monocyte chemotaxis (GO:0090025) | 3.19536511 |
| 66 | inositol phosphate-mediated signaling (GO:0048016) | 3.18697214 |
| 67 | regulation of defense response to virus by host (GO:0050691) | 3.05105243 |
| 68 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.02974881 |
| 69 | DNA excision (GO:0044349) | 3.02795144 |
| 70 | nucleotide-excision repair, DNA damage removal (GO:0000718) | 3.02795144 |
| 71 | establishment of viral latency (GO:0019043) | 3.02669364 |
| 72 | macromolecular complex disassembly (GO:0032984) | 3.02376425 |
| 73 | maintenance of protein location in nucleus (GO:0051457) | 2.99711273 |
| 74 | piRNA metabolic process (GO:0034587) | 2.96588159 |
| 75 | glomerulus development (GO:0032835) | 2.96338661 |
| 76 | protein targeting to membrane (GO:0006612) | 2.87725524 |
| 77 | protein targeting to lysosome (GO:0006622) | 2.87675194 |
| 78 | establishment of protein localization to vacuole (GO:0072666) | 2.87675194 |
| 79 | protein targeting to vacuole (GO:0006623) | 2.87675194 |
| 80 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.86891266 |
| 81 | regulation of activation of Janus kinase activity (GO:0010533) | 2.86385327 |
| 82 | regulation of signal transduction by p53 class mediator (GO:1901796) | 2.84352003 |
| 83 | cysteine metabolic process (GO:0006534) | 2.80956735 |
| 84 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.80921578 |
| 85 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.78259944 |
| 86 | transcription from RNA polymerase I promoter (GO:0006360) | 2.76091077 |
| 87 | alanine transport (GO:0032328) | 2.74581241 |
| 88 | proline transport (GO:0015824) | 2.69283168 |
| 89 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.68988974 |
| 90 | negative regulation of mast cell activation (GO:0033004) | 2.68916047 |
| 91 | chromosome organization involved in meiosis (GO:0070192) | 2.68506399 |
| 92 | response to phenylpropanoid (GO:0080184) | 2.67827384 |
| 93 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.63072962 |
| 94 | metallo-sulfur cluster assembly (GO:0031163) | 2.62813095 |
| 95 | iron-sulfur cluster assembly (GO:0016226) | 2.62813095 |
| 96 | IMP biosynthetic process (GO:0006188) | 2.61207506 |
| 97 | response to UV-B (GO:0010224) | 2.60686159 |
| 98 | activation of MAPKKK activity (GO:0000185) | 16.4894980 |
| 99 | leukocyte aggregation (GO:0070486) | 12.6075375 |
| 100 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 10.5361594 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.65805852 |
| 2 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.49100419 |
| 3 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 3.12711880 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.08103121 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.00305365 |
| 6 | STAT1_20625510_ChIP-Seq_HELA_Human | 2.72042285 |
| 7 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.46049036 |
| 8 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.44205418 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.39770207 |
| 10 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.29772594 |
| 11 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 2.26484394 |
| 12 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.21250512 |
| 13 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.17722264 |
| 14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.04437947 |
| 15 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.94469576 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.92068235 |
| 17 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.91444981 |
| 18 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.85637784 |
| 19 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.81535596 |
| 20 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.79685361 |
| 21 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.72013834 |
| 22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.71408534 |
| 23 | AR_20517297_ChIP-Seq_VCAP_Human | 1.71224811 |
| 24 | TP53_16413492_ChIP-PET_HCT116_Human | 1.57635578 |
| 25 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.57130055 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.56582540 |
| 27 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.54486844 |
| 28 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.52762256 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51702277 |
| 30 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.50984829 |
| 31 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.50151982 |
| 32 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.49416087 |
| 33 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.49223190 |
| 34 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.48806079 |
| 35 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.46263600 |
| 36 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.41693535 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40928002 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40928002 |
| 39 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.40176579 |
| 40 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.37150955 |
| 41 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.34432443 |
| 42 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.33406493 |
| 43 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.32227246 |
| 44 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.31591640 |
| 45 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.31520325 |
| 46 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28318260 |
| 47 | NCOR_22424771_ChIP-Seq_293T_Human | 1.28003933 |
| 48 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.26860676 |
| 49 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.25958412 |
| 50 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.24841761 |
| 51 | FUS_26573619_Chip-Seq_HEK293_Human | 1.22290626 |
| 52 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.22226779 |
| 53 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.20914650 |
| 54 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.20513836 |
| 55 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.19027598 |
| 56 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.18761897 |
| 57 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.18758437 |
| 58 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.17881784 |
| 59 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.17833333 |
| 60 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.14153926 |
| 61 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.12806658 |
| 62 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12389235 |
| 63 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.11635363 |
| 64 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.11363772 |
| 65 | SOX2_21211035_ChIP-Seq_LN229_Human | 1.11342110 |
| 66 | VDR_22108803_ChIP-Seq_LS180_Human | 1.10418016 |
| 67 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.10363962 |
| 68 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.09756336 |
| 69 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.08860733 |
| 70 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.08081931 |
| 71 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.07908087 |
| 72 | ETS1_21867929_ChIP-Seq_TH2_Mouse | 1.06767517 |
| 73 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.05822285 |
| 74 | SA1_27219007_Chip-Seq_Bcells_Human | 1.04981752 |
| 75 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04672258 |
| 76 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.04501346 |
| 77 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.02729280 |
| 78 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.01791639 |
| 79 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.01464810 |
| 80 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.01363443 |
| 81 | NFI_21473784_ChIP-Seq_ESCs_Mouse | 1.00902374 |
| 82 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.00672257 |
| 83 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.00610061 |
| 84 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.00395693 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99194683 |
| 86 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.99179027 |
| 87 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99126582 |
| 88 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99126582 |
| 89 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.98444638 |
| 90 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.98202449 |
| 91 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.97962926 |
| 92 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.97962926 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.97207546 |
| 94 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.95050800 |
| 95 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.94973540 |
| 96 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.94768896 |
| 97 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.93913738 |
| 98 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92740543 |
| 99 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.92652764 |
| 100 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.91529699 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000750_abnormal_muscle_regeneration | 5.44201464 |
| 2 | MP0000013_abnormal_adipose_tissue | 4.30380771 |
| 3 | MP0009384_cardiac_valve_regurgitation | 3.99056845 |
| 4 | MP0009379_abnormal_foot_pigmentation | 3.31455520 |
| 5 | MP0002938_white_spotting | 3.31406452 |
| 6 | MP0002638_abnormal_pupillary_reflex | 3.22732096 |
| 7 | MP0003786_premature_aging | 2.92647615 |
| 8 | MP0000858_altered_metastatic_potential | 2.54980713 |
| 9 | MP0004947_skin_inflammation | 2.17454955 |
| 10 | MP0002277_abnormal_respiratory_mucosa | 2.11800366 |
| 11 | MP0000762_abnormal_tongue_morphology | 2.09692880 |
| 12 | MP0005623_abnormal_meninges_morphology | 11.8189530 |
| 13 | MP0005671_abnormal_response_to | 1.95255581 |
| 14 | MP0006292_abnormal_olfactory_placode | 1.86901303 |
| 15 | MP0003385_abnormal_body_wall | 1.86108688 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.83404842 |
| 17 | MP0004147_increased_porphyrin_level | 1.77089037 |
| 18 | MP0009764_decreased_sensitivity_to | 1.69130166 |
| 19 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.60812438 |
| 20 | MP0005410_abnormal_fertilization | 1.47297197 |
| 21 | MP0006082_CNS_inflammation | 1.39290578 |
| 22 | MP0002177_abnormal_outer_ear | 1.36027088 |
| 23 | MP0010307_abnormal_tumor_latency | 1.35588138 |
| 24 | MP0002269_muscular_atrophy | 1.32652660 |
| 25 | MP0003787_abnormal_imprinting | 1.31739638 |
| 26 | MP0003115_abnormal_respiratory_system | 1.30023667 |
| 27 | MP0004142_abnormal_muscle_tone | 1.25131049 |
| 28 | MP0003121_genomic_imprinting | 1.21481756 |
| 29 | MP0002067_abnormal_sensory_capabilities | 1.20401373 |
| 30 | MP0000343_altered_response_to | 1.19758658 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.19695669 |
| 32 | MP0003122_maternal_imprinting | 1.18756605 |
| 33 | MP0000003_abnormal_adipose_tissue | 1.13672372 |
| 34 | MP0008770_decreased_survivor_rate | 1.13315546 |
| 35 | MP0009046_muscle_twitch | 1.09878291 |
| 36 | MP0008877_abnormal_DNA_methylation | 1.09087702 |
| 37 | MP0004087_abnormal_muscle_fiber | 1.02346690 |
| 38 | MP0002163_abnormal_gland_morphology | 0.97453373 |
| 39 | MP0008775_abnormal_heart_ventricle | 0.95634536 |
| 40 | MP0004130_abnormal_muscle_cell | 0.92054814 |
| 41 | MP0009765_abnormal_xenobiotic_induced | 0.91775940 |
| 42 | MP0003137_abnormal_impulse_conducting | 0.90464549 |
| 43 | MP0006276_abnormal_autonomic_nervous | 0.87972226 |
| 44 | MP0002102_abnormal_ear_morphology | 0.86981607 |
| 45 | MP0005195_abnormal_posterior_eye | 0.86532221 |
| 46 | MP0005379_endocrine/exocrine_gland_phen | 0.83779600 |
| 47 | MP0002160_abnormal_reproductive_system | 0.83593529 |
| 48 | MP0002272_abnormal_nervous_system | 0.81311416 |
| 49 | MP0003755_abnormal_palate_morphology | 0.80484062 |
| 50 | MP0001800_abnormal_humoral_immune | 0.79786187 |
| 51 | MP0003690_abnormal_glial_cell | 0.78973423 |
| 52 | MP0005389_reproductive_system_phenotype | 0.78504803 |
| 53 | MP0001502_abnormal_circadian_rhythm | 0.78302999 |
| 54 | MP0003279_aneurysm | 0.76725059 |
| 55 | MP0008872_abnormal_physiological_respon | 0.74513178 |
| 56 | MP0003221_abnormal_cardiomyocyte_apopto | 0.74261587 |
| 57 | MP0002132_abnormal_respiratory_system | 0.73064700 |
| 58 | MP0003698_abnormal_male_reproductive | 0.70426037 |
| 59 | MP0009785_altered_susceptibility_to | 0.68683134 |
| 60 | MP0008875_abnormal_xenobiotic_pharmacok | 0.66789857 |
| 61 | MP0002572_abnormal_emotion/affect_behav | 0.66227488 |
| 62 | MP0002837_dystrophic_cardiac_calcinosis | 0.65554449 |
| 63 | MP0008873_increased_physiological_sensi | 0.61631166 |
| 64 | MP0002106_abnormal_muscle_physiology | 0.61507252 |
| 65 | MP0008874_decreased_physiological_sensi | 0.57577110 |
| 66 | MP0002019_abnormal_tumor_incidence | 0.57278723 |
| 67 | MP0008058_abnormal_DNA_repair | 0.56424099 |
| 68 | MP0003763_abnormal_thymus_physiology | 0.55432537 |
| 69 | MP0009745_abnormal_behavioral_response | 0.55111013 |
| 70 | MP0005645_abnormal_hypothalamus_physiol | 0.55021954 |
| 71 | MP0000631_abnormal_neuroendocrine_gland | 0.54955110 |
| 72 | MP0002733_abnormal_thermal_nociception | 0.54917097 |
| 73 | MP0001905_abnormal_dopamine_level | 0.54731704 |
| 74 | MP0000749_muscle_degeneration | 0.53386024 |
| 75 | MP0002752_abnormal_somatic_nervous | 0.53272257 |
| 76 | MP0003806_abnormal_nucleotide_metabolis | 0.52098070 |
| 77 | MP0003699_abnormal_female_reproductive | 0.51544136 |
| 78 | MP0002723_abnormal_immune_serum | 0.50708828 |
| 79 | MP0002876_abnormal_thyroid_physiology | 0.50321140 |
| 80 | MP0002933_joint_inflammation | 0.49805453 |
| 81 | MP0009250_abnormal_appendicular_skeleto | 0.49690506 |
| 82 | MP0005369_muscle_phenotype | 0.48885459 |
| 83 | MP0008469_abnormal_protein_level | 0.48727105 |
| 84 | MP0001929_abnormal_gametogenesis | 0.48584796 |
| 85 | MP0001145_abnormal_male_reproductive | 0.48111884 |
| 86 | MP0002882_abnormal_neuron_morphology | 0.47489801 |
| 87 | MP0002210_abnormal_sex_determination | 0.46438811 |
| 88 | MP0002452_abnormal_antigen_presenting | 0.46314365 |
| 89 | MP0005423_abnormal_somatic_nervous | 0.46027777 |
| 90 | MP0003011_delayed_dark_adaptation | 0.45797340 |
| 91 | MP0002063_abnormal_learning/memory/cond | 0.44451491 |
| 92 | MP0003724_increased_susceptibility_to | 0.43745215 |
| 93 | MP0005164_abnormal_response_to | 0.43346923 |
| 94 | MP0003186_abnormal_redox_activity | 0.43297136 |
| 95 | MP0000653_abnormal_sex_gland | 0.43191719 |
| 96 | MP0003866_abnormal_defecation | 0.43013970 |
| 97 | MP0002161_abnormal_fertility/fecundity | 0.42933807 |
| 98 | MP0002653_abnormal_ependyma_morphology | 0.42179739 |
| 99 | MP0005025_abnormal_response_to | 0.42033632 |
| 100 | MP0000778_abnormal_nervous_system | 0.42001364 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Retinal dysplasia (HP:0007973) | 9.24548291 |
| 2 | Hypoplasia of the pons (HP:0012110) | 8.95040891 |
| 3 | Abnormality of the pons (HP:0007361) | 8.03484153 |
| 4 | Fatigue (HP:0012378) | 7.95237792 |
| 5 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 7.39633887 |
| 6 | Buphthalmos (HP:0000557) | 7.14118429 |
| 7 | Difficulty climbing stairs (HP:0003551) | 7.04542712 |
| 8 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 6.71169095 |
| 9 | Abolished electroretinogram (ERG) (HP:0000550) | 5.58174983 |
| 10 | Entropion (HP:0000621) | 4.46831419 |
| 11 | Megalocornea (HP:0000485) | 4.27468306 |
| 12 | Congenital glaucoma (HP:0001087) | 4.27234594 |
| 13 | Generalized hypotonia (HP:0001290) | 4.02973738 |
| 14 | Severe muscular hypotonia (HP:0006829) | 4.00487462 |
| 15 | Lissencephaly (HP:0001339) | 3.71487666 |
| 16 | Abnormality of DNA repair (HP:0003254) | 3.69458554 |
| 17 | Poikiloderma (HP:0001029) | 3.55122321 |
| 18 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.17776892 |
| 19 | Hypoplasia of the brainstem (HP:0002365) | 3.17611081 |
| 20 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 3.17611081 |
| 21 | Meningocele (HP:0002435) | 3.09701147 |
| 22 | Intellectual disability, profound (HP:0002187) | 3.08486212 |
| 23 | Generalized muscle weakness (HP:0003324) | 3.02030225 |
| 24 | Abnormality of the vitreous humor (HP:0004327) | 2.99450167 |
| 25 | Pallor (HP:0000980) | 2.94707187 |
| 26 | Gowers sign (HP:0003391) | 2.93964739 |
| 27 | Abnormality of vision evoked potentials (HP:0000649) | 2.91708165 |
| 28 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.83288314 |
| 29 | IgG deficiency (HP:0004315) | 2.78919881 |
| 30 | Non-midline cleft lip (HP:0100335) | 2.75440038 |
| 31 | Fragile nails (HP:0001808) | 2.71764408 |
| 32 | Pachygyria (HP:0001302) | 2.70648086 |
| 33 | Increased IgM level (HP:0003496) | 2.62301847 |
| 34 | Severe global developmental delay (HP:0011344) | 2.59888341 |
| 35 | Decreased subcutaneous fat (HP:0001002) | 2.54907013 |
| 36 | Mesangial abnormality (HP:0001966) | 2.54166439 |
| 37 | Submucous cleft hard palate (HP:0000176) | 2.49253704 |
| 38 | Muscular dystrophy (HP:0003560) | 2.48576004 |
| 39 | Supranuclear gaze palsy (HP:0000605) | 2.46330677 |
| 40 | Erythroderma (HP:0001019) | 2.40964932 |
| 41 | Papilledema (HP:0001085) | 2.37007746 |
| 42 | Muscle stiffness (HP:0003552) | 2.31555012 |
| 43 | Keratitis (HP:0000491) | 2.19423621 |
| 44 | Cone-rod dystrophy (HP:0000548) | 2.07446794 |
| 45 | Prominent metopic ridge (HP:0005487) | 2.00569945 |
| 46 | Eosinophilia (HP:0001880) | 2.00222880 |
| 47 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.00108905 |
| 48 | Retinal atrophy (HP:0001105) | 11.7973233 |
| 49 | Cerebellar dysplasia (HP:0007033) | 11.7092516 |
| 50 | Type II lissencephaly (HP:0007260) | 10.4171844 |
| 51 | Brittle hair (HP:0002299) | 1.91304729 |
| 52 | Abnormality of the metopic suture (HP:0005556) | 1.82714167 |
| 53 | Slow saccadic eye movements (HP:0000514) | 1.81656095 |
| 54 | Holoprosencephaly (HP:0001360) | 1.81348561 |
| 55 | Abnormality of subcutaneous fat tissue (HP:0001001) | 1.80844522 |
| 56 | Stenosis of the external auditory canal (HP:0000402) | 1.80141928 |
| 57 | Rectal prolapse (HP:0002035) | 1.79284564 |
| 58 | Nephronophthisis (HP:0000090) | 1.78425867 |
| 59 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.76354227 |
| 60 | Ectropion (HP:0000656) | 1.73513282 |
| 61 | Molar tooth sign on MRI (HP:0002419) | 1.72156732 |
| 62 | Abnormality of midbrain morphology (HP:0002418) | 1.72156732 |
| 63 | Polymicrogyria (HP:0002126) | 1.69651591 |
| 64 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.64264684 |
| 65 | Sacral dimple (HP:0000960) | 1.64019032 |
| 66 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.63115741 |
| 67 | Dandy-Walker malformation (HP:0001305) | 1.59723151 |
| 68 | Cerebral hypomyelination (HP:0006808) | 1.51241510 |
| 69 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.50618488 |
| 70 | Ileus (HP:0002595) | 1.49785916 |
| 71 | Retinal detachment (HP:0000541) | 1.47396624 |
| 72 | Everted lower lip vermilion (HP:0000232) | 1.45729425 |
| 73 | Medial flaring of the eyebrow (HP:0010747) | 1.44432300 |
| 74 | Chronic hepatic failure (HP:0100626) | 1.43197783 |
| 75 | Reticulocytopenia (HP:0001896) | 1.42446702 |
| 76 | Granulocytopenia (HP:0001913) | 1.42208007 |
| 77 | Nephropathy (HP:0000112) | 1.39639305 |
| 78 | Omphalocele (HP:0001539) | 1.38701599 |
| 79 | Hypoalbuminemia (HP:0003073) | 1.38387077 |
| 80 | Abnormal albumin level (HP:0012116) | 1.38387077 |
| 81 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.36209654 |
| 82 | Absent/shortened dynein arms (HP:0200106) | 1.36209654 |
| 83 | Abnormality of eosinophils (HP:0001879) | 1.34174837 |
| 84 | Diastasis recti (HP:0001540) | 1.33855427 |
| 85 | Death in childhood (HP:0003819) | 1.33221069 |
| 86 | Cellular immunodeficiency (HP:0005374) | 1.32383284 |
| 87 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.31739824 |
| 88 | Abnormality of the renal medulla (HP:0100957) | 1.30754679 |
| 89 | Intellectual disability, severe (HP:0010864) | 1.30277058 |
| 90 | Tubular atrophy (HP:0000092) | 1.29982386 |
| 91 | Decreased muscle mass (HP:0003199) | 1.29453782 |
| 92 | Colon cancer (HP:0003003) | 1.29084370 |
| 93 | Conical tooth (HP:0000698) | 1.28557009 |
| 94 | Myoclonus (HP:0001336) | 1.28257073 |
| 95 | Asplenia (HP:0001746) | 1.27392359 |
| 96 | Pancreatic fibrosis (HP:0100732) | 1.27283323 |
| 97 | Abnormality of incisor morphology (HP:0011063) | 1.26850869 |
| 98 | Cerebellar hypoplasia (HP:0001321) | 1.26545746 |
| 99 | Septo-optic dysplasia (HP:0100842) | 1.25247115 |
| 100 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.24770969 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK3 | 9.15996926 |
| 2 | STK10 | 9.08475337 |
| 3 | PIM1 | 3.56621864 |
| 4 | STK11 | 3.24930238 |
| 5 | TXK | 2.89352216 |
| 6 | PTK2B | 2.73060228 |
| 7 | LMTK2 | 2.64556808 |
| 8 | MAP4K1 | 2.08778897 |
| 9 | NLK | 1.86374671 |
| 10 | MAP3K11 | 1.66806458 |
| 11 | PRKCH | 1.65878358 |
| 12 | MAP4K2 | 1.54819787 |
| 13 | STK16 | 1.46113336 |
| 14 | PIK3CA | 1.32065396 |
| 15 | EPHA3 | 1.08419290 |
| 16 | FRK | 1.07469118 |
| 17 | PHKG2 | 0.99604440 |
| 18 | PHKG1 | 0.99604440 |
| 19 | MAP3K13 | 0.93906304 |
| 20 | MAP3K12 | 0.90067735 |
| 21 | CDK19 | 0.85478458 |
| 22 | CLK1 | 0.85101873 |
| 23 | DYRK2 | 0.83614865 |
| 24 | MAP2K2 | 0.81568077 |
| 25 | ADRBK2 | 0.80925893 |
| 26 | EPHB2 | 0.71304762 |
| 27 | GSK3A | 0.68696432 |
| 28 | GRK1 | 0.68177841 |
| 29 | TAOK3 | 0.66323387 |
| 30 | WNK4 | 0.63262379 |
| 31 | IKBKB | 0.61930342 |
| 32 | IRAK1 | 0.60125849 |
| 33 | TYRO3 | 0.59855534 |
| 34 | CSNK1G3 | 0.58452009 |
| 35 | MAPK15 | 0.52940723 |
| 36 | PRKCE | 0.51074929 |
| 37 | CSNK1A1L | 0.50120324 |
| 38 | PRKCQ | 0.47252129 |
| 39 | LCK | 0.46682291 |
| 40 | AKT2 | 0.46438608 |
| 41 | CSNK1G2 | 0.46360599 |
| 42 | INSRR | 0.46102600 |
| 43 | PRKCG | 0.45885292 |
| 44 | WNK3 | 0.45720864 |
| 45 | MELK | 0.44474128 |
| 46 | TLK1 | 0.44000130 |
| 47 | WNK1 | 0.43200474 |
| 48 | CSNK1G1 | 0.42089864 |
| 49 | TIE1 | 0.41934039 |
| 50 | OBSCN | 0.41072386 |
| 51 | PKN1 | 0.40883892 |
| 52 | MAPK13 | 0.39006469 |
| 53 | TAOK2 | 0.38853262 |
| 54 | CDC7 | 0.38816820 |
| 55 | SGK3 | 0.38671155 |
| 56 | DYRK1A | 0.38535541 |
| 57 | PRKCI | 0.37143054 |
| 58 | MAPK7 | 0.36694308 |
| 59 | GRK7 | 0.36474718 |
| 60 | ZAP70 | 0.36261306 |
| 61 | CAMKK2 | 0.35491192 |
| 62 | HIPK2 | 0.35027973 |
| 63 | MAP2K7 | 0.34177442 |
| 64 | MAP2K4 | 0.33812747 |
| 65 | CSNK1D | 0.33719714 |
| 66 | RPS6KA5 | 0.32886606 |
| 67 | FYN | 0.32313432 |
| 68 | CSNK1A1 | 0.31928074 |
| 69 | RPS6KA6 | 0.29737878 |
| 70 | BLK | 0.29412242 |
| 71 | ERBB2 | 0.28542699 |
| 72 | PRKCD | 0.28524744 |
| 73 | YES1 | 0.28443696 |
| 74 | LYN | 0.26744687 |
| 75 | PRKACA | 0.26332848 |
| 76 | MAP3K4 | 0.26146613 |
| 77 | BRSK2 | 0.25521348 |
| 78 | PRKG2 | 0.25309988 |
| 79 | CSNK2A2 | 0.24295632 |
| 80 | MUSK | 0.24077191 |
| 81 | SGK1 | 0.21847664 |
| 82 | IGF1R | 0.21763003 |
| 83 | NTRK2 | 0.21715333 |
| 84 | MAPK14 | 0.21649580 |
| 85 | CAMK2A | 0.21390307 |
| 86 | CSNK1E | 0.21300027 |
| 87 | RPS6KB2 | 0.19738634 |
| 88 | TEC | 0.19252770 |
| 89 | PIK3CG | 0.19209057 |
| 90 | CAMK1 | 0.18466184 |
| 91 | CSK | 0.17496457 |
| 92 | EGFR | 0.17421342 |
| 93 | RPS6KA3 | 0.17056237 |
| 94 | PRKACG | 0.16979883 |
| 95 | KDR | 0.16516901 |
| 96 | ROCK1 | 0.16390939 |
| 97 | PRKCA | 0.16024022 |
| 98 | RPS6KC1 | 0.15743579 |
| 99 | RPS6KL1 | 0.15743579 |
| 100 | FGFR4 | 0.15659985 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 5.60102775 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.76353769 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 4.09789439 |
| 4 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 3.84581421 |
| 5 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.83631316 |
| 6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.68406308 |
| 7 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.42679101 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.31701497 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.28277667 |
| 10 | Basal transcription factors_Homo sapiens_hsa03022 | 2.28108449 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.15261695 |
| 12 | Leishmaniasis_Homo sapiens_hsa05140 | 1.91870036 |
| 13 | Parkinsons disease_Homo sapiens_hsa05012 | 1.79251879 |
| 14 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70086130 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.68149621 |
| 16 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.62642472 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.56435952 |
| 18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.50583205 |
| 19 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.45082861 |
| 20 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.42445807 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.42406366 |
| 22 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.42045152 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.38919952 |
| 24 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.37673746 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.34356857 |
| 26 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.28254874 |
| 27 | Insulin secretion_Homo sapiens_hsa04911 | 1.27344428 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27166492 |
| 29 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.18614759 |
| 30 | Mineral absorption_Homo sapiens_hsa04978 | 1.18122953 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15617745 |
| 32 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.10866082 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.07233450 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.06964157 |
| 35 | RNA polymerase_Homo sapiens_hsa03020 | 1.04641454 |
| 36 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.00663223 |
| 37 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.96945650 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.95143994 |
| 39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.90286644 |
| 40 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.87704370 |
| 41 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.86354954 |
| 42 | Homologous recombination_Homo sapiens_hsa03440 | 0.80759963 |
| 43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.78719180 |
| 44 | Cocaine addiction_Homo sapiens_hsa05030 | 0.73664999 |
| 45 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.70871789 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.67716409 |
| 47 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.67278704 |
| 48 | Phagosome_Homo sapiens_hsa04145 | 0.66977483 |
| 49 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.62605154 |
| 50 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61529029 |
| 51 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.60417178 |
| 52 | Bile secretion_Homo sapiens_hsa04976 | 0.58781378 |
| 53 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.58096021 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.56124974 |
| 55 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54665604 |
| 56 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54543674 |
| 57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53693566 |
| 58 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.50965972 |
| 59 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.50964778 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48195143 |
| 61 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48129922 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47309451 |
| 63 | Peroxisome_Homo sapiens_hsa04146 | 0.46520108 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.46445459 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.45920419 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.44462492 |
| 67 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44056317 |
| 68 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.43737229 |
| 69 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.43143158 |
| 70 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.42884666 |
| 71 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42726011 |
| 72 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.41085686 |
| 73 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.38833116 |
| 74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38562738 |
| 75 | Viral myocarditis_Homo sapiens_hsa05416 | 0.35758267 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.35210226 |
| 77 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.34835957 |
| 78 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.34775285 |
| 79 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.34534688 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34206484 |
| 81 | Proteasome_Homo sapiens_hsa03050 | 0.33559993 |
| 82 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.33548409 |
| 83 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.33304310 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.32739728 |
| 85 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.32203441 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.31423980 |
| 87 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.31175481 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.30971696 |
| 89 | RNA degradation_Homo sapiens_hsa03018 | 0.30856537 |
| 90 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.30360008 |
| 91 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.29924780 |
| 92 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.29716987 |
| 93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.29190068 |
| 94 | Salivary secretion_Homo sapiens_hsa04970 | 0.27451199 |
| 95 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.27380814 |
| 96 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.27280316 |
| 97 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.26729522 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.26523439 |
| 99 | Phototransduction_Homo sapiens_hsa04744 | 0.24219629 |
| 100 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.23569800 |

