

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of prostaglandin secretion (GO:0032308) | 9.90742417 |
| 2 | regulation of prostaglandin secretion (GO:0032306) | 8.44684417 |
| 3 | regulation of corticosteroid hormone secretion (GO:2000846) | 8.43342886 |
| 4 | viral transcription (GO:0019083) | 7.92515757 |
| 5 | behavioral response to nicotine (GO:0035095) | 7.64601364 |
| 6 | translational termination (GO:0006415) | 7.46191097 |
| 7 | positive regulation of icosanoid secretion (GO:0032305) | 7.30787473 |
| 8 | positive regulation of fatty acid transport (GO:2000193) | 6.87015914 |
| 9 | translational elongation (GO:0006414) | 6.37915838 |
| 10 | ribosomal small subunit assembly (GO:0000028) | 6.34035072 |
| 11 | regulation of appetite (GO:0032098) | 6.31087893 |
| 12 | regulation of steroid hormone secretion (GO:2000831) | 6.16730049 |
| 13 | negative regulation of cholesterol transport (GO:0032375) | 6.12245131 |
| 14 | negative regulation of sterol transport (GO:0032372) | 6.12245131 |
| 15 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.89851851 |
| 16 | viral life cycle (GO:0019058) | 5.88245287 |
| 17 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 5.80196602 |
| 18 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 5.80110749 |
| 19 | ribosomal small subunit biogenesis (GO:0042274) | 5.79467066 |
| 20 | cotranslational protein targeting to membrane (GO:0006613) | 5.76959478 |
| 21 | protein targeting to ER (GO:0045047) | 5.74464842 |
| 22 | locomotory exploration behavior (GO:0035641) | 5.68947130 |
| 23 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 5.64011852 |
| 24 | cellular protein complex disassembly (GO:0043624) | 5.62136436 |
| 25 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 5.56100965 |
| 26 | regulation of icosanoid secretion (GO:0032303) | 5.50940884 |
| 27 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.50885700 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 5.38260337 |
| 29 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.34062134 |
| 30 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 4.97734876 |
| 31 | protein complex disassembly (GO:0043241) | 4.76336964 |
| 32 | protein neddylation (GO:0045116) | 4.73113030 |
| 33 | anterograde synaptic vesicle transport (GO:0048490) | 4.62595224 |
| 34 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.46742080 |
| 35 | translational initiation (GO:0006413) | 4.44534786 |
| 36 | inner ear receptor cell development (GO:0060119) | 4.43957190 |
| 37 | macromolecular complex disassembly (GO:0032984) | 4.39971590 |
| 38 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 4.37721262 |
| 39 | ATP synthesis coupled proton transport (GO:0015986) | 4.26228183 |
| 40 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.26228183 |
| 41 | exploration behavior (GO:0035640) | 4.19948814 |
| 42 | regulation of cholesterol efflux (GO:0010874) | 4.14139358 |
| 43 | positive regulation of organic acid transport (GO:0032892) | 4.06157897 |
| 44 | synaptic transmission, cholinergic (GO:0007271) | 3.97570586 |
| 45 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.88768630 |
| 46 | protein targeting to membrane (GO:0006612) | 3.76589280 |
| 47 | positive regulation of protein sumoylation (GO:0033235) | 3.75598938 |
| 48 | maturation of SSU-rRNA (GO:0030490) | 3.59245802 |
| 49 | positive regulation of vascular permeability (GO:0043117) | 3.56011305 |
| 50 | negative regulation of astrocyte differentiation (GO:0048712) | 3.44276936 |
| 51 | positive regulation of lipid storage (GO:0010884) | 3.42946331 |
| 52 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 3.40182568 |
| 53 | reflex (GO:0060004) | 3.39314964 |
| 54 | melanosome organization (GO:0032438) | 3.38291018 |
| 55 | ribosomal large subunit biogenesis (GO:0042273) | 3.37919759 |
| 56 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.30478117 |
| 57 | anterograde axon cargo transport (GO:0008089) | 3.27339354 |
| 58 | regulation of endocrine process (GO:0044060) | 3.25537271 |
| 59 | nonmotile primary cilium assembly (GO:0035058) | 3.24547931 |
| 60 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.23140229 |
| 61 | pigmentation (GO:0043473) | 3.20845217 |
| 62 | regulation of fatty acid transport (GO:2000191) | 3.13626936 |
| 63 | pigment granule organization (GO:0048753) | 3.13425896 |
| 64 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.11368642 |
| 65 | phosphatidylserine metabolic process (GO:0006658) | 3.10791768 |
| 66 | mRNA catabolic process (GO:0006402) | 3.07489400 |
| 67 | peptide hormone processing (GO:0016486) | 3.02803679 |
| 68 | phosphatidic acid metabolic process (GO:0046473) | 3.02391620 |
| 69 | phosphatidic acid biosynthetic process (GO:0006654) | 3.02391620 |
| 70 | cysteine metabolic process (GO:0006534) | 2.98389000 |
| 71 | positive regulation of receptor biosynthetic process (GO:0010870) | 2.95619925 |
| 72 | regulation of macrophage activation (GO:0043030) | 2.90985493 |
| 73 | metallo-sulfur cluster assembly (GO:0031163) | 2.83721146 |
| 74 | iron-sulfur cluster assembly (GO:0016226) | 2.83721146 |
| 75 | auditory receptor cell differentiation (GO:0042491) | 2.83696670 |
| 76 | primary amino compound metabolic process (GO:1901160) | 2.80843753 |
| 77 | cell proliferation in forebrain (GO:0021846) | 2.77237518 |
| 78 | regulation of microtubule-based movement (GO:0060632) | 2.75355982 |
| 79 | apoptotic DNA fragmentation (GO:0006309) | 2.75161570 |
| 80 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 2.71284071 |
| 81 | translation (GO:0006412) | 2.67624613 |
| 82 | RNA catabolic process (GO:0006401) | 2.65573435 |
| 83 | positive regulation of hair follicle development (GO:0051798) | 2.64046945 |
| 84 | positive regulation of hair cycle (GO:0042635) | 2.64046945 |
| 85 | phosphatidylglycerol metabolic process (GO:0046471) | 2.59422550 |
| 86 | signal complex assembly (GO:0007172) | 2.59326987 |
| 87 | lens fiber cell differentiation (GO:0070306) | 2.56859978 |
| 88 | establishment of protein localization to membrane (GO:0090150) | 2.55273148 |
| 89 | ncRNA 3-end processing (GO:0043628) | 2.54657573 |
| 90 | middle ear morphogenesis (GO:0042474) | 2.54116818 |
| 91 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.53728893 |
| 92 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.51410120 |
| 93 | negative regulation of lipid transport (GO:0032369) | 2.51362532 |
| 94 | positive regulation of cell fate commitment (GO:0010455) | 2.50984973 |
| 95 | positive regulation of growth hormone secretion (GO:0060124) | 2.48656018 |
| 96 | regulation of ruffle assembly (GO:1900027) | 2.47427838 |
| 97 | pyrimidine dimer repair (GO:0006290) | 2.47164955 |
| 98 | alditol phosphate metabolic process (GO:0052646) | 2.43822715 |
| 99 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.42045708 |
| 100 | regulation of glucocorticoid secretion (GO:2000849) | 10.2479250 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 8.02278662 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.78484514 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.94977758 |
| 4 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.85293688 |
| 5 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.78023070 |
| 6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.51737343 |
| 7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.51038332 |
| 8 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.47511219 |
| 9 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.39216795 |
| 10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.34256815 |
| 11 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.32929800 |
| 12 | STAT1_20625510_ChIP-Seq_HELA_Human | 2.18244436 |
| 13 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.13912046 |
| 14 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.12392984 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.07893848 |
| 16 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.02087262 |
| 17 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.02087262 |
| 18 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.99631870 |
| 19 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.84680681 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.81304559 |
| 21 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.79312614 |
| 22 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.78511021 |
| 23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.77762104 |
| 24 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.74951629 |
| 25 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.70293848 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.68971396 |
| 27 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.61813437 |
| 28 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.58528209 |
| 29 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.55305865 |
| 30 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.53955831 |
| 31 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.52492851 |
| 32 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.50652899 |
| 33 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.46674500 |
| 34 | NCOR_22424771_ChIP-Seq_293T_Human | 1.46283258 |
| 35 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.45823262 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.45625503 |
| 37 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.45378500 |
| 38 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44905855 |
| 39 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.43680025 |
| 40 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.42606053 |
| 41 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.41708481 |
| 42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40753059 |
| 43 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.37836854 |
| 44 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.36781785 |
| 45 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.35873146 |
| 46 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.34060032 |
| 47 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.31439942 |
| 48 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.29351286 |
| 49 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27466384 |
| 50 | VDR_22108803_ChIP-Seq_LS180_Human | 1.26158974 |
| 51 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.25464084 |
| 52 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.25346752 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.22778485 |
| 54 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.20691066 |
| 55 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20097381 |
| 56 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 1.18243796 |
| 57 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.18015831 |
| 58 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.16839194 |
| 59 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.16019558 |
| 60 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.15704225 |
| 61 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.12360399 |
| 62 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.09237167 |
| 63 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.07968310 |
| 64 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.07680087 |
| 65 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.06939377 |
| 66 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06492353 |
| 67 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.06148196 |
| 68 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.04627663 |
| 69 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.01415794 |
| 70 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.00887636 |
| 71 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00874847 |
| 72 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00562768 |
| 73 | AR_25329375_ChIP-Seq_VCAP_Human | 1.00116979 |
| 74 | FUS_26573619_Chip-Seq_HEK293_Human | 0.99714069 |
| 75 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.98827674 |
| 76 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.98417423 |
| 77 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.97390968 |
| 78 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.97104183 |
| 79 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.96676118 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.96676118 |
| 81 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94434848 |
| 82 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94434848 |
| 83 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.92048885 |
| 84 | RXR_22108803_ChIP-Seq_LS180_Human | 0.91859436 |
| 85 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.91466345 |
| 86 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.90530204 |
| 87 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.90320172 |
| 88 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.90268836 |
| 89 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.89027694 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.88752027 |
| 91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.88752027 |
| 92 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.88726751 |
| 93 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.87952554 |
| 94 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.87214043 |
| 95 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.85699964 |
| 96 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.85424007 |
| 97 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.85347332 |
| 98 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.84713669 |
| 99 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.83292097 |
| 100 | TP53_16413492_ChIP-PET_HCT116_Human | 0.82335499 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 6.93888424 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.22772295 |
| 3 | MP0001968_abnormal_touch/_nociception | 4.04275304 |
| 4 | MP0002909_abnormal_adrenal_gland | 3.90803843 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.30326531 |
| 6 | MP0005083_abnormal_biliary_tract | 2.66120446 |
| 7 | MP0001905_abnormal_dopamine_level | 2.54826588 |
| 8 | MP0002638_abnormal_pupillary_reflex | 2.47352202 |
| 9 | MP0003879_abnormal_hair_cell | 2.46378541 |
| 10 | MP0008789_abnormal_olfactory_epithelium | 2.22036813 |
| 11 | MP0000343_altered_response_to | 2.14847002 |
| 12 | MP0010386_abnormal_urinary_bladder | 2.06634584 |
| 13 | MP0003787_abnormal_imprinting | 2.03763258 |
| 14 | MP0002163_abnormal_gland_morphology | 1.93011998 |
| 15 | MP0001440_abnormal_grooming_behavior | 1.85413565 |
| 16 | MP0005409_darkened_coat_color | 1.83402181 |
| 17 | MP0000537_abnormal_urethra_morphology | 1.82317153 |
| 18 | MP0005394_taste/olfaction_phenotype | 1.80507661 |
| 19 | MP0005499_abnormal_olfactory_system | 1.80507661 |
| 20 | MP0002160_abnormal_reproductive_system | 1.75900660 |
| 21 | MP0003122_maternal_imprinting | 1.74377165 |
| 22 | MP0002938_white_spotting | 1.59153121 |
| 23 | MP0009745_abnormal_behavioral_response | 1.58996581 |
| 24 | MP0009840_abnormal_foam_cell | 1.55960389 |
| 25 | MP0000639_abnormal_adrenal_gland | 1.49444936 |
| 26 | MP0005645_abnormal_hypothalamus_physiol | 1.48764727 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.45178720 |
| 28 | MP0008877_abnormal_DNA_methylation | 1.44394368 |
| 29 | MP0003638_abnormal_response/metabolism_ | 1.43037957 |
| 30 | MP0003123_paternal_imprinting | 1.40778897 |
| 31 | MP0000026_abnormal_inner_ear | 1.38952076 |
| 32 | MP0003279_aneurysm | 1.38647674 |
| 33 | MP0002557_abnormal_social/conspecific_i | 1.37235579 |
| 34 | MP0003011_delayed_dark_adaptation | 1.30683440 |
| 35 | MP0000371_diluted_coat_color | 1.30471716 |
| 36 | MP0004484_altered_response_of | 1.29890701 |
| 37 | MP0000566_synostosis | 1.27315209 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.26319289 |
| 39 | MP0005386_behavior/neurological_phenoty | 1.26287234 |
| 40 | MP0004924_abnormal_behavior | 1.26287234 |
| 41 | MP0005448_abnormal_energy_balance | 1.25723224 |
| 42 | MP0003121_genomic_imprinting | 1.23885392 |
| 43 | MP0004742_abnormal_vestibular_system | 1.23323411 |
| 44 | MP0009333_abnormal_splenocyte_physiolog | 1.23105675 |
| 45 | MP0001963_abnormal_hearing_physiology | 1.22294903 |
| 46 | MP0004142_abnormal_muscle_tone | 1.22032837 |
| 47 | MP0005389_reproductive_system_phenotype | 1.21512534 |
| 48 | MP0005085_abnormal_gallbladder_physiolo | 1.15543444 |
| 49 | MP0000049_abnormal_middle_ear | 1.15483632 |
| 50 | MP0004885_abnormal_endolymph | 1.14483624 |
| 51 | MP0003880_abnormal_central_pattern | 1.14145234 |
| 52 | MP0002572_abnormal_emotion/affect_behav | 1.12381513 |
| 53 | MP0000230_abnormal_systemic_arterial | 1.10346829 |
| 54 | MP0000538_abnormal_urinary_bladder | 1.10082555 |
| 55 | MP0002063_abnormal_learning/memory/cond | 1.09261434 |
| 56 | MP0002837_dystrophic_cardiac_calcinosis | 1.09035838 |
| 57 | MP0002184_abnormal_innervation | 1.06215030 |
| 58 | MP0009053_abnormal_anal_canal | 1.04409786 |
| 59 | MP0006276_abnormal_autonomic_nervous | 1.03771434 |
| 60 | MP0006072_abnormal_retinal_apoptosis | 1.03609472 |
| 61 | MP0000778_abnormal_nervous_system | 1.02453704 |
| 62 | MP0002277_abnormal_respiratory_mucosa | 1.02424550 |
| 63 | MP0002735_abnormal_chemical_nociception | 0.99505760 |
| 64 | MP0003938_abnormal_ear_development | 0.99347842 |
| 65 | MP0009384_cardiac_valve_regurgitation | 0.98356501 |
| 66 | MP0009115_abnormal_fat_cell | 0.94937025 |
| 67 | MP0003283_abnormal_digestive_organ | 0.94197152 |
| 68 | MP0002067_abnormal_sensory_capabilities | 0.93770379 |
| 69 | MP0002272_abnormal_nervous_system | 0.89182590 |
| 70 | MP0006054_spinal_hemorrhage | 0.86783219 |
| 71 | MP0000569_abnormal_digit_pigmentation | 0.86374960 |
| 72 | MP0010030_abnormal_orbit_morphology | 0.85993028 |
| 73 | MP0003635_abnormal_synaptic_transmissio | 0.85334318 |
| 74 | MP0005379_endocrine/exocrine_gland_phen | 0.84957297 |
| 75 | MP0002064_seizures | 0.84859023 |
| 76 | MP0005671_abnormal_response_to | 0.83899618 |
| 77 | MP0001502_abnormal_circadian_rhythm | 0.83186130 |
| 78 | MP0002876_abnormal_thyroid_physiology | 0.79962238 |
| 79 | MP0003315_abnormal_perineum_morphology | 0.79827029 |
| 80 | MP0005551_abnormal_eye_electrophysiolog | 0.79755860 |
| 81 | MP0002075_abnormal_coat/hair_pigmentati | 0.79682314 |
| 82 | MP0002249_abnormal_larynx_morphology | 0.79475612 |
| 83 | MP0001765_abnormal_ion_homeostasis | 0.79072077 |
| 84 | MP0002233_abnormal_nose_morphology | 0.78728955 |
| 85 | MP0001970_abnormal_pain_threshold | 0.78611452 |
| 86 | MP0002095_abnormal_skin_pigmentation | 0.77943274 |
| 87 | MP0000465_gastrointestinal_hemorrhage | 0.77362072 |
| 88 | MP0008775_abnormal_heart_ventricle | 0.76432746 |
| 89 | MP0002733_abnormal_thermal_nociception | 0.74710375 |
| 90 | MP0004145_abnormal_muscle_electrophysio | 0.74646437 |
| 91 | MP0003646_muscle_fatigue | 0.73352627 |
| 92 | MP0002752_abnormal_somatic_nervous | 0.71735050 |
| 93 | MP0001986_abnormal_taste_sensitivity | 0.70871216 |
| 94 | MP0002653_abnormal_ependyma_morphology | 0.70761765 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 0.70671936 |
| 96 | MP0003698_abnormal_male_reproductive | 0.66934908 |
| 97 | MP0001486_abnormal_startle_reflex | 0.65382025 |
| 98 | MP0009780_abnormal_chondrocyte_physiolo | 0.64888087 |
| 99 | MP0000428_abnormal_craniofacial_morphol | 0.63778203 |
| 100 | MP0005623_abnormal_meninges_morphology | 0.63525138 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Symptomatic seizures (HP:0011145) | 8.30080606 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.21362374 |
| 3 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.83364199 |
| 4 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.83364199 |
| 5 | Reduced antithrombin III activity (HP:0001976) | 3.62167041 |
| 6 | Facial hemangioma (HP:0000329) | 3.58538793 |
| 7 | Hyperlipoproteinemia (HP:0010980) | 3.57928662 |
| 8 | Macrocytic anemia (HP:0001972) | 3.41419088 |
| 9 | Abnormal number of erythroid precursors (HP:0012131) | 3.40391895 |
| 10 | Reticulocytopenia (HP:0001896) | 3.27171494 |
| 11 | Pallor (HP:0000980) | 3.09099774 |
| 12 | Short chin (HP:0000331) | 3.05444986 |
| 13 | Stenosis of the external auditory canal (HP:0000402) | 3.03667678 |
| 14 | Hyperthyroidism (HP:0000836) | 2.96130549 |
| 15 | Abnormal protein glycosylation (HP:0012346) | 2.92607643 |
| 16 | Abnormal glycosylation (HP:0012345) | 2.92607643 |
| 17 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.92607643 |
| 18 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.92607643 |
| 19 | Hypochromic microcytic anemia (HP:0004840) | 2.91345149 |
| 20 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.87330003 |
| 21 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.78749373 |
| 22 | Abnormality of DNA repair (HP:0003254) | 2.69757673 |
| 23 | Protruding tongue (HP:0010808) | 2.67923850 |
| 24 | Septo-optic dysplasia (HP:0100842) | 2.67907886 |
| 25 | Abnormality of the columella (HP:0009929) | 2.67533120 |
| 26 | Thoracolumbar scoliosis (HP:0002944) | 2.67524653 |
| 27 | Partial duplication of thumb phalanx (HP:0009944) | 2.67225287 |
| 28 | Asplenia (HP:0001746) | 2.63542471 |
| 29 | Xanthomatosis (HP:0000991) | 2.61463948 |
| 30 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.55154198 |
| 31 | Polydipsia (HP:0001959) | 2.51033429 |
| 32 | Abnormal drinking behavior (HP:0030082) | 2.51033429 |
| 33 | Poikiloderma (HP:0001029) | 2.50796626 |
| 34 | Decreased circulating renin level (HP:0003351) | 2.44629292 |
| 35 | Partial duplication of the phalanx of hand (HP:0009999) | 2.37151491 |
| 36 | Rib fusion (HP:0000902) | 2.34831580 |
| 37 | Pendular nystagmus (HP:0012043) | 2.27428279 |
| 38 | Abnormality of the labia minora (HP:0012880) | 2.26291608 |
| 39 | Colon cancer (HP:0003003) | 2.25940607 |
| 40 | Hypoplasia of the radius (HP:0002984) | 2.23182163 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.18367120 |
| 42 | Myokymia (HP:0002411) | 2.17396119 |
| 43 | Limb dystonia (HP:0002451) | 2.16369414 |
| 44 | Vitreoretinal degeneration (HP:0000655) | 2.14479801 |
| 45 | Abolished electroretinogram (ERG) (HP:0000550) | 2.12855983 |
| 46 | Syncope (HP:0001279) | 2.11003363 |
| 47 | Protuberant abdomen (HP:0001538) | 2.10468668 |
| 48 | Hypoplasia of the ulna (HP:0003022) | 2.09051463 |
| 49 | Humeroradial synostosis (HP:0003041) | 2.06717550 |
| 50 | Synostosis involving the elbow (HP:0003938) | 2.06717550 |
| 51 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.04452708 |
| 52 | Gait imbalance (HP:0002141) | 2.02960833 |
| 53 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.02418706 |
| 54 | Prolonged QT interval (HP:0001657) | 2.00646957 |
| 55 | Hypoglycemic seizures (HP:0002173) | 11.8527199 |
| 56 | Hyperglycinemia (HP:0002154) | 1.98610397 |
| 57 | Absent thumb (HP:0009777) | 1.97740490 |
| 58 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.91786044 |
| 59 | Polyuria (HP:0000103) | 1.91016435 |
| 60 | Sleep apnea (HP:0010535) | 1.91013145 |
| 61 | Adrenal hypoplasia (HP:0000835) | 1.89587182 |
| 62 | Abnormality of the renal cortex (HP:0011035) | 1.89148167 |
| 63 | Abnormality of renal excretion (HP:0011036) | 1.84446534 |
| 64 | Abnormality of the nasal septum (HP:0000419) | 1.84016187 |
| 65 | Esophageal atresia (HP:0002032) | 1.82802081 |
| 66 | Congenital sensorineural hearing impairment (HP:0008527) | 1.81037454 |
| 67 | Maternal diabetes (HP:0009800) | 1.81028161 |
| 68 | Depressed nasal ridge (HP:0000457) | 1.80965359 |
| 69 | Acute necrotizing encephalopathy (HP:0006965) | 1.80580557 |
| 70 | Pancreatic fibrosis (HP:0100732) | 1.80574991 |
| 71 | Congenital primary aphakia (HP:0007707) | 1.79594899 |
| 72 | Fused cervical vertebrae (HP:0002949) | 1.77781626 |
| 73 | Absent septum pellucidum (HP:0001331) | 1.75920859 |
| 74 | Enlarged kidneys (HP:0000105) | 1.75655962 |
| 75 | Abnormal hemoglobin (HP:0011902) | 1.74725572 |
| 76 | Vaginal atresia (HP:0000148) | 1.73743266 |
| 77 | Forearm undergrowth (HP:0009821) | 1.73680851 |
| 78 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.72700889 |
| 79 | Thoracic kyphosis (HP:0002942) | 1.71720841 |
| 80 | Tubular atrophy (HP:0000092) | 1.70481327 |
| 81 | Generalized hypotonia (HP:0001290) | 1.69610481 |
| 82 | Genital tract atresia (HP:0001827) | 1.66695088 |
| 83 | Hepatocellular necrosis (HP:0001404) | 1.65637942 |
| 84 | Capillary hemangiomas (HP:0005306) | 1.65264884 |
| 85 | Pancreatic cysts (HP:0001737) | 1.65063895 |
| 86 | Hypothermia (HP:0002045) | 1.64691259 |
| 87 | Abnormality of midbrain morphology (HP:0002418) | 1.62890325 |
| 88 | Molar tooth sign on MRI (HP:0002419) | 1.62890325 |
| 89 | Chorioretinal atrophy (HP:0000533) | 1.59976231 |
| 90 | Entropion (HP:0000621) | 1.59307726 |
| 91 | Abnormality of the renal medulla (HP:0100957) | 1.58812986 |
| 92 | Abnormal urine output (HP:0012590) | 1.58605830 |
| 93 | Generalized aminoaciduria (HP:0002909) | 1.58495951 |
| 94 | Duplication of thumb phalanx (HP:0009942) | 1.58388969 |
| 95 | Hyperaldosteronism (HP:0000859) | 1.57145400 |
| 96 | Agitation (HP:0000713) | 1.56757443 |
| 97 | Truncus arteriosus (HP:0001660) | 1.56305190 |
| 98 | Male pseudohermaphroditism (HP:0000037) | 1.55838226 |
| 99 | Abnormality of the aortic arch (HP:0012303) | 1.55477727 |
| 100 | Hyperphosphatemia (HP:0002905) | 1.55318155 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 5.71235573 |
| 2 | WNK4 | 4.73299776 |
| 3 | ADRBK2 | 4.61482332 |
| 4 | STK39 | 4.19171512 |
| 5 | PRKD2 | 3.87207592 |
| 6 | NTRK3 | 3.49614739 |
| 7 | ABL2 | 2.75936616 |
| 8 | WNK1 | 2.22335660 |
| 9 | ERBB2 | 2.10769921 |
| 10 | WNK3 | 2.09462966 |
| 11 | EPHA4 | 2.07379937 |
| 12 | GRK1 | 1.68911016 |
| 13 | CLK1 | 1.61646658 |
| 14 | ADRBK1 | 1.50603758 |
| 15 | TXK | 1.50380956 |
| 16 | FGFR2 | 1.47573186 |
| 17 | MAP2K7 | 1.41071198 |
| 18 | DYRK3 | 1.38463396 |
| 19 | DYRK1A | 1.37424638 |
| 20 | MAPK13 | 1.35293196 |
| 21 | NEK1 | 1.33835731 |
| 22 | EPHB2 | 1.26690097 |
| 23 | STK16 | 1.17586416 |
| 24 | LRRK2 | 1.16052275 |
| 25 | PRKCG | 1.14433264 |
| 26 | TEC | 1.13512806 |
| 27 | PINK1 | 1.13483845 |
| 28 | OXSR1 | 1.12870418 |
| 29 | ZAK | 1.07948253 |
| 30 | DYRK2 | 1.06219398 |
| 31 | CDK19 | 1.05125007 |
| 32 | PIK3CA | 1.00822265 |
| 33 | MAPK15 | 0.99848491 |
| 34 | MAP3K4 | 0.98758417 |
| 35 | MARK1 | 0.95972395 |
| 36 | RPS6KA5 | 0.94685643 |
| 37 | SGK3 | 0.94141183 |
| 38 | ERN1 | 0.91252710 |
| 39 | MAP4K2 | 0.84579101 |
| 40 | FRK | 0.81868035 |
| 41 | MINK1 | 0.80895797 |
| 42 | INSRR | 0.75354870 |
| 43 | PLK4 | 0.75296787 |
| 44 | PRKACA | 0.74345341 |
| 45 | CAMKK2 | 0.73587502 |
| 46 | PHKG2 | 0.72892792 |
| 47 | PHKG1 | 0.72892792 |
| 48 | PAK3 | 0.72635437 |
| 49 | BMPR1B | 0.72293862 |
| 50 | MUSK | 0.72268683 |
| 51 | LYN | 0.71965814 |
| 52 | CDC42BPA | 0.69651844 |
| 53 | PRKD1 | 0.67690232 |
| 54 | CSNK1E | 0.66794095 |
| 55 | NTRK2 | 0.65179744 |
| 56 | GRK7 | 0.63793363 |
| 57 | OBSCN | 0.63715922 |
| 58 | PTK6 | 0.63545862 |
| 59 | AURKB | 0.62418147 |
| 60 | PRKCD | 0.58692149 |
| 61 | TIE1 | 0.55965108 |
| 62 | CSNK2A2 | 0.54512497 |
| 63 | PDPK1 | 0.53078178 |
| 64 | MAP4K1 | 0.52792734 |
| 65 | CDK8 | 0.51885951 |
| 66 | DYRK1B | 0.50899938 |
| 67 | PASK | 0.50644345 |
| 68 | NME2 | 0.50477643 |
| 69 | CDK11A | 0.50364633 |
| 70 | CAMKK1 | 0.49331169 |
| 71 | AURKA | 0.48231202 |
| 72 | TYRO3 | 0.47344987 |
| 73 | PRKCQ | 0.46229479 |
| 74 | FYN | 0.46165438 |
| 75 | CAMK1 | 0.45674007 |
| 76 | NEK2 | 0.43760844 |
| 77 | PRKCZ | 0.43516696 |
| 78 | ABL1 | 0.42755438 |
| 79 | CSNK2A1 | 0.40762157 |
| 80 | SGK1 | 0.40668744 |
| 81 | PRKCA | 0.39167219 |
| 82 | MAP3K11 | 0.36711192 |
| 83 | HCK | 0.35997806 |
| 84 | MAP2K4 | 0.35617989 |
| 85 | PDK2 | 0.34973070 |
| 86 | PTK2B | 0.34527239 |
| 87 | CAMK2A | 0.34526404 |
| 88 | DAPK3 | 0.34044015 |
| 89 | CDK15 | 0.32912293 |
| 90 | PRKG1 | 0.32711560 |
| 91 | PRKD3 | 0.32533893 |
| 92 | CDK5 | 0.32461501 |
| 93 | KDR | 0.32281830 |
| 94 | PRKCH | 0.32262621 |
| 95 | CASK | 0.31743316 |
| 96 | PKN1 | 0.30564785 |
| 97 | PAK1 | 0.29180051 |
| 98 | CSNK1A1 | 0.28951811 |
| 99 | RPS6KA3 | 0.28793087 |
| 100 | CDK14 | 0.28466708 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.16025078 |
| 2 | Sulfur relay system_Homo sapiens_hsa04122 | 5.46593277 |
| 3 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 4.46754297 |
| 4 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 4.40647189 |
| 5 | Fat digestion and absorption_Homo sapiens_hsa04975 | 3.18800273 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.44477148 |
| 7 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.38362765 |
| 8 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.17038846 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.96075644 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 1.88701095 |
| 11 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.72476824 |
| 12 | Nicotine addiction_Homo sapiens_hsa05033 | 1.60865093 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.59085105 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 1.56982359 |
| 15 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.53997961 |
| 16 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.49709283 |
| 17 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.34479293 |
| 18 | Olfactory transduction_Homo sapiens_hsa04740 | 1.33437415 |
| 19 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.28237971 |
| 20 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.26627529 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.20758712 |
| 22 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.17427043 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.15908368 |
| 24 | Morphine addiction_Homo sapiens_hsa05032 | 1.13620614 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.09824322 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03797544 |
| 27 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.03220369 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.02977363 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.99149513 |
| 30 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.93187305 |
| 31 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.89321454 |
| 32 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.88541685 |
| 33 | DNA replication_Homo sapiens_hsa03030 | 0.88069915 |
| 34 | Circadian entrainment_Homo sapiens_hsa04713 | 0.87562079 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.87458783 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86622244 |
| 37 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86596596 |
| 38 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.85247300 |
| 39 | Melanogenesis_Homo sapiens_hsa04916 | 0.85203964 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 0.83367440 |
| 41 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.82823152 |
| 42 | Axon guidance_Homo sapiens_hsa04360 | 0.81949959 |
| 43 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.81307116 |
| 44 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.80894834 |
| 45 | Insulin secretion_Homo sapiens_hsa04911 | 0.79702022 |
| 46 | Homologous recombination_Homo sapiens_hsa03440 | 0.77569019 |
| 47 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.75923911 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.75208721 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.75011528 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.71166081 |
| 51 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.70670526 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.67483283 |
| 53 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.67456705 |
| 54 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65386832 |
| 55 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64594626 |
| 56 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.63285992 |
| 57 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.55963982 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53641117 |
| 59 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.52861401 |
| 60 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.52835217 |
| 61 | Taste transduction_Homo sapiens_hsa04742 | 0.52403655 |
| 62 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52164461 |
| 63 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.51926423 |
| 64 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.51719171 |
| 65 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51198047 |
| 66 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.51115906 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.48660163 |
| 68 | Salivary secretion_Homo sapiens_hsa04970 | 0.48034516 |
| 69 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45728400 |
| 70 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.42453972 |
| 71 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.41848911 |
| 72 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.41422657 |
| 73 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.40451314 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39945296 |
| 75 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.37775428 |
| 76 | Asthma_Homo sapiens_hsa05310 | 0.37506716 |
| 77 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.35735931 |
| 78 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.31193655 |
| 79 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30563277 |
| 80 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30399082 |
| 81 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29926912 |
| 82 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.29515017 |
| 83 | Cocaine addiction_Homo sapiens_hsa05030 | 0.28515174 |
| 84 | RNA polymerase_Homo sapiens_hsa03020 | 0.28318662 |
| 85 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.27874947 |
| 86 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27205910 |
| 87 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.26892018 |
| 88 | Purine metabolism_Homo sapiens_hsa00230 | 0.26736943 |
| 89 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26199649 |
| 90 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.25422731 |
| 91 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.24797540 |
| 92 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24437747 |
| 93 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.23880516 |
| 94 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.23649008 |
| 95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.23610007 |
| 96 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.22482588 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.21709256 |
| 98 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.21274589 |
| 99 | Bile secretion_Homo sapiens_hsa04976 | 0.20709699 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.19849860 |

