

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 9.59469714 |
| 2 | translational termination (GO:0006415) | 9.18038264 |
| 3 | ribosomal small subunit biogenesis (GO:0042274) | 8.89845667 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 8.00462109 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 7.74052625 |
| 6 | translational elongation (GO:0006414) | 7.66997723 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 7.60509212 |
| 8 | protein targeting to ER (GO:0045047) | 7.58710013 |
| 9 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 7.25772637 |
| 10 | protein localization to endoplasmic reticulum (GO:0070972) | 7.16276773 |
| 11 | cellular protein complex disassembly (GO:0043624) | 6.91933759 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 6.90819996 |
| 13 | viral life cycle (GO:0019058) | 6.75670332 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.74541832 |
| 15 | activation of MAPKKK activity (GO:0000185) | 6.39917582 |
| 16 | chaperone-mediated protein transport (GO:0072321) | 6.29651249 |
| 17 | translational initiation (GO:0006413) | 6.04888694 |
| 18 | protein complex disassembly (GO:0043241) | 5.76659450 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 5.66428517 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.66428517 |
| 21 | macromolecular complex disassembly (GO:0032984) | 5.40338440 |
| 22 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 5.38972024 |
| 23 | negative regulation of mast cell activation (GO:0033004) | 5.27777089 |
| 24 | ribosomal large subunit biogenesis (GO:0042273) | 5.17752016 |
| 25 | protein targeting to membrane (GO:0006612) | 5.15978454 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.07590014 |
| 27 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.89394275 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.89394275 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 4.89394275 |
| 30 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.82339945 |
| 31 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.80312232 |
| 32 | translation (GO:0006412) | 4.78119429 |
| 33 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.62058689 |
| 34 | mRNA catabolic process (GO:0006402) | 4.53208860 |
| 35 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 4.33368248 |
| 36 | protein complex biogenesis (GO:0070271) | 4.28919371 |
| 37 | leukocyte aggregation (GO:0070486) | 4.26637464 |
| 38 | respiratory electron transport chain (GO:0022904) | 4.12848178 |
| 39 | electron transport chain (GO:0022900) | 4.07604188 |
| 40 | DNA deamination (GO:0045006) | 4.06021996 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.05889927 |
| 42 | RNA catabolic process (GO:0006401) | 4.03418473 |
| 43 | regulation of cilium movement (GO:0003352) | 4.02991714 |
| 44 | termination of RNA polymerase III transcription (GO:0006386) | 4.02273905 |
| 45 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.02273905 |
| 46 | protein neddylation (GO:0045116) | 3.99743388 |
| 47 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.89563111 |
| 48 | cellular component biogenesis (GO:0044085) | 3.85811748 |
| 49 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.83549661 |
| 50 | regulation of activation of Janus kinase activity (GO:0010533) | 3.73425716 |
| 51 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.67330626 |
| 52 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.67330626 |
| 53 | nonmotile primary cilium assembly (GO:0035058) | 3.66485477 |
| 54 | positive regulation of vascular permeability (GO:0043117) | 3.66148894 |
| 55 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.49545782 |
| 56 | establishment of protein localization to membrane (GO:0090150) | 3.47210622 |
| 57 | rRNA transcription (GO:0009303) | 3.45244797 |
| 58 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.39078268 |
| 59 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.39008939 |
| 60 | protein targeting (GO:0006605) | 3.34294673 |
| 61 | GTP biosynthetic process (GO:0006183) | 3.33144204 |
| 62 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.32399217 |
| 63 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.26926863 |
| 64 | base-excision repair, AP site formation (GO:0006285) | 3.23089547 |
| 65 | pseudouridine synthesis (GO:0001522) | 3.22857041 |
| 66 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.20530664 |
| 67 | establishment of protein localization to organelle (GO:0072594) | 3.16890146 |
| 68 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 3.11950704 |
| 69 | rRNA metabolic process (GO:0016072) | 3.11539879 |
| 70 | behavioral response to nicotine (GO:0035095) | 3.11351852 |
| 71 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.11342451 |
| 72 | transcription from RNA polymerase I promoter (GO:0006360) | 3.09798905 |
| 73 | somite development (GO:0061053) | 3.09351107 |
| 74 | ATP biosynthetic process (GO:0006754) | 3.04457688 |
| 75 | negative regulation of appetite (GO:0032099) | 3.02053300 |
| 76 | negative regulation of response to food (GO:0032096) | 3.02053300 |
| 77 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.01839793 |
| 78 | termination of RNA polymerase I transcription (GO:0006363) | 3.01406459 |
| 79 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.00974717 |
| 80 | iron-sulfur cluster assembly (GO:0016226) | 2.98831296 |
| 81 | metallo-sulfur cluster assembly (GO:0031163) | 2.98831296 |
| 82 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.98046123 |
| 83 | UTP biosynthetic process (GO:0006228) | 2.95163242 |
| 84 | kynurenine metabolic process (GO:0070189) | 2.84753204 |
| 85 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.81310177 |
| 86 | protein localization to membrane (GO:0072657) | 2.79994849 |
| 87 | regulation of microtubule-based movement (GO:0060632) | 2.78163491 |
| 88 | nucleotide-excision repair, DNA damage removal (GO:0000718) | 2.78095268 |
| 89 | DNA excision (GO:0044349) | 2.78095268 |
| 90 | peptidyl-histidine modification (GO:0018202) | 2.77577283 |
| 91 | rRNA processing (GO:0006364) | 2.77526844 |
| 92 | hydrogen ion transmembrane transport (GO:1902600) | 2.73700852 |
| 93 | epithelial cilium movement (GO:0003351) | 2.72704408 |
| 94 | protein targeting to mitochondrion (GO:0006626) | 2.72107669 |
| 95 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.70709187 |
| 96 | deoxyribonucleotide catabolic process (GO:0009264) | 2.70276281 |
| 97 | positive regulation of T cell apoptotic process (GO:0070234) | 2.68817684 |
| 98 | resolution of meiotic recombination intermediates (GO:0000712) | 2.68776387 |
| 99 | forebrain morphogenesis (GO:0048853) | 2.65076002 |
| 100 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.62606309 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.86700996 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.54899726 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.54466868 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.16482216 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.13715121 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.96927651 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.95097538 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.85483925 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.69161029 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.46854167 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.46440445 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.38597479 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.36760121 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.34578794 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.31749880 |
| 16 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.20009658 |
| 17 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.16609433 |
| 18 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.09925249 |
| 19 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 2.00952633 |
| 20 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.90047161 |
| 21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.84503642 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.83715200 |
| 23 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.75690774 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.75200494 |
| 25 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.72457430 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.71838215 |
| 27 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.71836061 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.66672522 |
| 29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.63751743 |
| 30 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.54710303 |
| 31 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.53855199 |
| 32 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.52738985 |
| 33 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.52022233 |
| 34 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.51288168 |
| 35 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.48829030 |
| 36 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.47706495 |
| 37 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.46743537 |
| 38 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.45175811 |
| 39 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.44602659 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.42063369 |
| 41 | VDR_22108803_ChIP-Seq_LS180_Human | 1.40640595 |
| 42 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.40279854 |
| 43 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.36947773 |
| 44 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.36574877 |
| 45 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.36334570 |
| 46 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.35119000 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.33034700 |
| 48 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.32852487 |
| 49 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.29375790 |
| 50 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.28210702 |
| 51 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.27621458 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27399918 |
| 53 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.26557038 |
| 54 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.25072104 |
| 55 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.21034914 |
| 56 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20792722 |
| 57 | SA1_27219007_Chip-Seq_Bcells_Human | 1.19525603 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19294910 |
| 59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.17909488 |
| 60 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17525701 |
| 61 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.17515517 |
| 62 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.17180681 |
| 63 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.16999184 |
| 64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.16218036 |
| 65 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.15911889 |
| 66 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.14214472 |
| 67 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.14133482 |
| 68 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.13781632 |
| 69 | P68_20966046_ChIP-Seq_HELA_Human | 1.10925103 |
| 70 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.09353962 |
| 71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.08343481 |
| 72 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.08343481 |
| 73 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.08206156 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 1.07758152 |
| 75 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.06735265 |
| 76 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.06358569 |
| 77 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.05802816 |
| 78 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.05790677 |
| 79 | EWS_26573619_Chip-Seq_HEK293_Human | 1.05633210 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.04618218 |
| 81 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.02359968 |
| 82 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.02023940 |
| 83 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.00662575 |
| 84 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.99681455 |
| 85 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.98491811 |
| 86 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98254480 |
| 87 | NCOR_22424771_ChIP-Seq_293T_Human | 0.97888413 |
| 88 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.97113084 |
| 89 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.97107382 |
| 90 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.97107382 |
| 91 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.95725750 |
| 92 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.95615371 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.94115698 |
| 94 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.93463998 |
| 95 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.90676216 |
| 96 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90477754 |
| 97 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.90169457 |
| 98 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.88421048 |
| 99 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.87219880 |
| 100 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87190779 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.69764388 |
| 2 | MP0005623_abnormal_meninges_morphology | 4.91789313 |
| 3 | MP0003646_muscle_fatigue | 4.47890108 |
| 4 | MP0006292_abnormal_olfactory_placode | 4.13269207 |
| 5 | MP0002163_abnormal_gland_morphology | 2.78562007 |
| 6 | MP0002938_white_spotting | 2.73192521 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.49177357 |
| 8 | MP0000750_abnormal_muscle_regeneration | 2.41960929 |
| 9 | MP0008789_abnormal_olfactory_epithelium | 2.39671645 |
| 10 | MP0004142_abnormal_muscle_tone | 2.09567057 |
| 11 | MP0003786_premature_aging | 1.93418809 |
| 12 | MP0009384_cardiac_valve_regurgitation | 1.92652445 |
| 13 | MP0004147_increased_porphyrin_level | 1.92473907 |
| 14 | MP0005499_abnormal_olfactory_system | 1.90487600 |
| 15 | MP0005394_taste/olfaction_phenotype | 1.90487600 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.85450323 |
| 17 | MP0003787_abnormal_imprinting | 1.82494835 |
| 18 | MP0003186_abnormal_redox_activity | 1.74998035 |
| 19 | MP0003011_delayed_dark_adaptation | 1.69589198 |
| 20 | MP0002102_abnormal_ear_morphology | 1.62630133 |
| 21 | MP0005389_reproductive_system_phenotype | 1.61736026 |
| 22 | MP0000049_abnormal_middle_ear | 1.61147278 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.60361175 |
| 24 | MP0002095_abnormal_skin_pigmentation | 1.54812559 |
| 25 | MP0004885_abnormal_endolymph | 1.50927555 |
| 26 | MP0002160_abnormal_reproductive_system | 1.47725126 |
| 27 | MP0001529_abnormal_vocalization | 1.47030954 |
| 28 | MP0005379_endocrine/exocrine_gland_phen | 1.45348463 |
| 29 | MP0003123_paternal_imprinting | 1.41103098 |
| 30 | MP0005377_hearing/vestibular/ear_phenot | 1.40209286 |
| 31 | MP0003878_abnormal_ear_physiology | 1.40209286 |
| 32 | MP0002736_abnormal_nociception_after | 1.38689461 |
| 33 | MP0006276_abnormal_autonomic_nervous | 1.33960197 |
| 34 | MP0002277_abnormal_respiratory_mucosa | 1.31005217 |
| 35 | MP0001919_abnormal_reproductive_system | 1.30559311 |
| 36 | MP0003385_abnormal_body_wall | 1.30068674 |
| 37 | MP0008775_abnormal_heart_ventricle | 1.26330852 |
| 38 | MP0005646_abnormal_pituitary_gland | 1.25747700 |
| 39 | MP0005671_abnormal_response_to | 1.24744866 |
| 40 | MP0008875_abnormal_xenobiotic_pharmacok | 1.22288784 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.21454829 |
| 42 | MP0001293_anophthalmia | 1.18279733 |
| 43 | MP0001440_abnormal_grooming_behavior | 1.15042665 |
| 44 | MP0001984_abnormal_olfaction | 1.14430995 |
| 45 | MP0005195_abnormal_posterior_eye | 1.13121802 |
| 46 | MP0003119_abnormal_digestive_system | 1.12710280 |
| 47 | MP0000631_abnormal_neuroendocrine_gland | 1.10432244 |
| 48 | MP0000762_abnormal_tongue_morphology | 1.08053272 |
| 49 | MP0001905_abnormal_dopamine_level | 1.07700267 |
| 50 | MP0002234_abnormal_pharynx_morphology | 1.06959187 |
| 51 | MP0002177_abnormal_outer_ear | 1.06701956 |
| 52 | MP0009053_abnormal_anal_canal | 1.06491090 |
| 53 | MP0003755_abnormal_palate_morphology | 1.06104487 |
| 54 | MP0000343_altered_response_to | 1.04213742 |
| 55 | MP0006036_abnormal_mitochondrial_physio | 1.03092280 |
| 56 | MP0000678_abnormal_parathyroid_gland | 0.99318133 |
| 57 | MP0008877_abnormal_DNA_methylation | 0.98495452 |
| 58 | MP0004130_abnormal_muscle_cell | 0.98307213 |
| 59 | MP0008872_abnormal_physiological_respon | 0.97919044 |
| 60 | MP0002653_abnormal_ependyma_morphology | 0.97367318 |
| 61 | MP0000013_abnormal_adipose_tissue | 0.96647554 |
| 62 | MP0009046_muscle_twitch | 0.96193887 |
| 63 | MP0008058_abnormal_DNA_repair | 0.92804599 |
| 64 | MP0000026_abnormal_inner_ear | 0.92250911 |
| 65 | MP0002233_abnormal_nose_morphology | 0.91460559 |
| 66 | MP0001485_abnormal_pinna_reflex | 0.91009014 |
| 67 | MP0002067_abnormal_sensory_capabilities | 0.90251807 |
| 68 | MP0002752_abnormal_somatic_nervous | 0.89444117 |
| 69 | MP0002272_abnormal_nervous_system | 0.88290855 |
| 70 | MP0002876_abnormal_thyroid_physiology | 0.87435948 |
| 71 | MP0003137_abnormal_impulse_conducting | 0.84695195 |
| 72 | MP0002210_abnormal_sex_determination | 0.83962301 |
| 73 | MP0003938_abnormal_ear_development | 0.81072526 |
| 74 | MP0002249_abnormal_larynx_morphology | 0.80186451 |
| 75 | MP0006072_abnormal_retinal_apoptosis | 0.79731112 |
| 76 | MP0001324_abnormal_eye_pigmentation | 0.77579745 |
| 77 | MP0009250_abnormal_appendicular_skeleto | 0.77062809 |
| 78 | MP0001986_abnormal_taste_sensitivity | 0.76652724 |
| 79 | MP0005410_abnormal_fertilization | 0.75444544 |
| 80 | MP0005645_abnormal_hypothalamus_physiol | 0.74686071 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.74497179 |
| 82 | MP0009745_abnormal_behavioral_response | 0.73404823 |
| 83 | MP0000015_abnormal_ear_pigmentation | 0.73048366 |
| 84 | MP0000858_altered_metastatic_potential | 0.71086950 |
| 85 | MP0010307_abnormal_tumor_latency | 0.70765498 |
| 86 | MP0004742_abnormal_vestibular_system | 0.69445479 |
| 87 | MP0004019_abnormal_vitamin_homeostasis | 0.68278976 |
| 88 | MP0003879_abnormal_hair_cell | 0.67311499 |
| 89 | MP0003195_calcinosis | 0.66780150 |
| 90 | MP0003115_abnormal_respiratory_system | 0.66657569 |
| 91 | MP0005332_abnormal_amino_acid | 0.66467071 |
| 92 | MP0009764_decreased_sensitivity_to | 0.65774086 |
| 93 | MP0003121_genomic_imprinting | 0.65057727 |
| 94 | MP0003698_abnormal_male_reproductive | 0.64075963 |
| 95 | MP0005408_hypopigmentation | 0.63793518 |
| 96 | MP0002116_abnormal_craniofacial_bone | 0.61057677 |
| 97 | MP0003122_maternal_imprinting | 0.60969907 |
| 98 | MP0005174_abnormal_tail_pigmentation | 0.58489535 |
| 99 | MP0002572_abnormal_emotion/affect_behav | 0.58304375 |
| 100 | MP0002269_muscular_atrophy | 0.56698172 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cerebellar dysplasia (HP:0007033) | 7.61844409 |
| 2 | Type II lissencephaly (HP:0007260) | 7.41990665 |
| 3 | Retinal atrophy (HP:0001105) | 6.60193073 |
| 4 | Hypoplasia of the pons (HP:0012110) | 5.64332458 |
| 5 | Retinal dysplasia (HP:0007973) | 5.45617541 |
| 6 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 5.27089958 |
| 7 | Abnormality of the pons (HP:0007361) | 5.03065845 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 4.72612277 |
| 9 | Pallor (HP:0000980) | 4.48725294 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.22660925 |
| 11 | Fatigue (HP:0012378) | 4.18426615 |
| 12 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.11004373 |
| 13 | Reticulocytopenia (HP:0001896) | 4.04069751 |
| 14 | Abolished electroretinogram (ERG) (HP:0000550) | 3.98483618 |
| 15 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 3.94328944 |
| 16 | Acute encephalopathy (HP:0006846) | 3.87064631 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.79874225 |
| 18 | Buphthalmos (HP:0000557) | 3.79408336 |
| 19 | Macrocytic anemia (HP:0001972) | 3.75141596 |
| 20 | Molar tooth sign on MRI (HP:0002419) | 3.55994126 |
| 21 | Abnormality of midbrain morphology (HP:0002418) | 3.55994126 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.48943934 |
| 23 | Mitochondrial inheritance (HP:0001427) | 3.45942728 |
| 24 | Severe muscular hypotonia (HP:0006829) | 3.28554625 |
| 25 | Abnormal number of erythroid precursors (HP:0012131) | 3.22738896 |
| 26 | Abnormality of DNA repair (HP:0003254) | 3.20216332 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.12785411 |
| 28 | Megalocornea (HP:0000485) | 3.09007946 |
| 29 | Increased CSF lactate (HP:0002490) | 3.05254044 |
| 30 | Lissencephaly (HP:0001339) | 2.93753417 |
| 31 | Difficulty climbing stairs (HP:0003551) | 2.84445128 |
| 32 | Cerebral edema (HP:0002181) | 2.80218148 |
| 33 | Abnormal hemoglobin (HP:0011902) | 2.77353353 |
| 34 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.62801990 |
| 35 | Nephronophthisis (HP:0000090) | 2.62680416 |
| 36 | Hyperglycinemia (HP:0002154) | 2.57123217 |
| 37 | Hepatocellular necrosis (HP:0001404) | 2.52062018 |
| 38 | Entropion (HP:0000621) | 2.47857699 |
| 39 | Poikiloderma (HP:0001029) | 2.46023130 |
| 40 | Colon cancer (HP:0003003) | 2.41166435 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.32500918 |
| 42 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.29930991 |
| 43 | Stenosis of the external auditory canal (HP:0000402) | 2.28008198 |
| 44 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.26750557 |
| 45 | Pachygyria (HP:0001302) | 2.21716902 |
| 46 | Increased IgM level (HP:0003496) | 2.20979444 |
| 47 | Pancreatic cysts (HP:0001737) | 2.20296831 |
| 48 | Absent/shortened dynein arms (HP:0200106) | 2.18622094 |
| 49 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.18622094 |
| 50 | Congenital glaucoma (HP:0001087) | 2.16500392 |
| 51 | Hepatic necrosis (HP:0002605) | 2.16208048 |
| 52 | Meningocele (HP:0002435) | 2.15318674 |
| 53 | Generalized muscle weakness (HP:0003324) | 2.14657393 |
| 54 | Increased hepatocellular lipid droplets (HP:0006565) | 2.13937342 |
| 55 | True hermaphroditism (HP:0010459) | 2.13767287 |
| 56 | Lipid accumulation in hepatocytes (HP:0006561) | 2.13642636 |
| 57 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.06335514 |
| 58 | Abnormality of the vitreous humor (HP:0004327) | 2.06051103 |
| 59 | Pancreatic fibrosis (HP:0100732) | 2.05554365 |
| 60 | Sclerocornea (HP:0000647) | 2.00536048 |
| 61 | Optic disc pallor (HP:0000543) | 1.99768124 |
| 62 | Leukodystrophy (HP:0002415) | 1.97145540 |
| 63 | IgG deficiency (HP:0004315) | 1.96354860 |
| 64 | Generalized hypotonia (HP:0001290) | 1.96217796 |
| 65 | Asplenia (HP:0001746) | 1.95765262 |
| 66 | Increased intramyocellular lipid droplets (HP:0012240) | 1.95693788 |
| 67 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.92884807 |
| 68 | Respiratory failure (HP:0002878) | 1.92884088 |
| 69 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.92846081 |
| 70 | Absent thumb (HP:0009777) | 1.91520273 |
| 71 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.90786138 |
| 72 | Decreased central vision (HP:0007663) | 1.88746260 |
| 73 | Anencephaly (HP:0002323) | 1.84614428 |
| 74 | Abnormality of the renal medulla (HP:0100957) | 1.82281930 |
| 75 | Fragile nails (HP:0001808) | 1.80858698 |
| 76 | Exercise intolerance (HP:0003546) | 1.78561534 |
| 77 | Holoprosencephaly (HP:0001360) | 1.78054638 |
| 78 | Polydipsia (HP:0001959) | 1.77248305 |
| 79 | Abnormal drinking behavior (HP:0030082) | 1.77248305 |
| 80 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.76235256 |
| 81 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.76235256 |
| 82 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.76183027 |
| 83 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.76183027 |
| 84 | Renal Fanconi syndrome (HP:0001994) | 1.73947290 |
| 85 | Chronic hepatic failure (HP:0100626) | 1.72186096 |
| 86 | Increased muscle lipid content (HP:0009058) | 1.71877452 |
| 87 | Impulsivity (HP:0100710) | 1.71801309 |
| 88 | Testicular atrophy (HP:0000029) | 1.71596243 |
| 89 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.71453494 |
| 90 | Hypoplasia of the brainstem (HP:0002365) | 1.71453494 |
| 91 | Non-midline cleft lip (HP:0100335) | 1.71341033 |
| 92 | Methylmalonic acidemia (HP:0002912) | 1.71210001 |
| 93 | Pendular nystagmus (HP:0012043) | 1.69976519 |
| 94 | Diastasis recti (HP:0001540) | 1.69687428 |
| 95 | Increased serum lactate (HP:0002151) | 1.68093229 |
| 96 | Decreased subcutaneous fat (HP:0001002) | 1.68030702 |
| 97 | Congenital stationary night blindness (HP:0007642) | 1.67863971 |
| 98 | Lactic acidosis (HP:0003128) | 1.66335428 |
| 99 | Rectal prolapse (HP:0002035) | 1.64520288 |
| 100 | Erythroderma (HP:0001019) | 1.64280936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK3 | 5.79031073 |
| 2 | STK10 | 4.68306617 |
| 3 | NME2 | 3.87744179 |
| 4 | LIMK1 | 2.64811060 |
| 5 | STK16 | 2.57718415 |
| 6 | CAMKK2 | 2.44866823 |
| 7 | BCKDK | 2.37921212 |
| 8 | PIM1 | 2.33488632 |
| 9 | STK11 | 2.25419397 |
| 10 | TXK | 2.20304114 |
| 11 | TLK1 | 2.14701532 |
| 12 | ZAK | 2.11041132 |
| 13 | MAP4K1 | 2.05580095 |
| 14 | MAP3K11 | 2.05308580 |
| 15 | ADRBK2 | 1.96557609 |
| 16 | GRK1 | 1.92285930 |
| 17 | CDK8 | 1.81110951 |
| 18 | PIK3CA | 1.78104823 |
| 19 | BRSK1 | 1.66801178 |
| 20 | DYRK2 | 1.64210685 |
| 21 | WNK4 | 1.56360974 |
| 22 | CDK19 | 1.48970655 |
| 23 | LRRK2 | 1.48257183 |
| 24 | TIE1 | 1.46782060 |
| 25 | PTK2B | 1.40862398 |
| 26 | ABL2 | 1.36348602 |
| 27 | CAMKK1 | 1.35435936 |
| 28 | CDC7 | 1.35130077 |
| 29 | RPS6KA5 | 1.29944126 |
| 30 | MAP4K2 | 1.23410237 |
| 31 | AURKA | 1.18427796 |
| 32 | WNK3 | 1.17175663 |
| 33 | PRKCH | 1.04085631 |
| 34 | CDC42BPA | 1.04025333 |
| 35 | PIM2 | 1.01362137 |
| 36 | MAP2K2 | 0.99631937 |
| 37 | INSRR | 0.98791255 |
| 38 | CAMK1 | 0.96961619 |
| 39 | BRSK2 | 0.95692908 |
| 40 | NTRK3 | 0.90064672 |
| 41 | IKBKB | 0.89932693 |
| 42 | PRKCG | 0.82093388 |
| 43 | PDK2 | 0.78689872 |
| 44 | PRKCQ | 0.78598830 |
| 45 | CSNK2A2 | 0.76287982 |
| 46 | CHEK2 | 0.75524815 |
| 47 | EPHA4 | 0.73903335 |
| 48 | FRK | 0.73326256 |
| 49 | MAP3K4 | 0.72219473 |
| 50 | LMTK2 | 0.69064650 |
| 51 | RPS6KA6 | 0.67836837 |
| 52 | ARAF | 0.66763258 |
| 53 | NEK1 | 0.63949790 |
| 54 | NLK | 0.63464448 |
| 55 | STK39 | 0.61445793 |
| 56 | CLK1 | 0.60441579 |
| 57 | EPHB2 | 0.60060209 |
| 58 | MAP3K13 | 0.59527351 |
| 59 | ILK | 0.56162364 |
| 60 | NTRK2 | 0.56028286 |
| 61 | MELK | 0.55282453 |
| 62 | CSNK2A1 | 0.54764140 |
| 63 | DAPK3 | 0.54708474 |
| 64 | PLK1 | 0.53561145 |
| 65 | OBSCN | 0.53421569 |
| 66 | DAPK2 | 0.51836176 |
| 67 | RPS6KC1 | 0.50881445 |
| 68 | RPS6KL1 | 0.50881445 |
| 69 | ADRBK1 | 0.50821593 |
| 70 | PRKACA | 0.50266978 |
| 71 | PKN1 | 0.46543970 |
| 72 | PLK4 | 0.45167499 |
| 73 | AURKB | 0.44507643 |
| 74 | MAPKAPK5 | 0.44079066 |
| 75 | ATR | 0.43311916 |
| 76 | CAMK4 | 0.40348746 |
| 77 | OXSR1 | 0.39270816 |
| 78 | PASK | 0.38876105 |
| 79 | MST4 | 0.38284807 |
| 80 | MAP2K7 | 0.35931990 |
| 81 | NUAK1 | 0.34346688 |
| 82 | CAMK1D | 0.33407137 |
| 83 | MAPK13 | 0.32448379 |
| 84 | PRKCI | 0.32196673 |
| 85 | MUSK | 0.30646490 |
| 86 | CSNK1G3 | 0.30432092 |
| 87 | CSNK1E | 0.29708078 |
| 88 | GRK7 | 0.28793383 |
| 89 | LCK | 0.28731582 |
| 90 | CHEK1 | 0.28299006 |
| 91 | GSK3A | 0.28262830 |
| 92 | PINK1 | 0.28026133 |
| 93 | BRAF | 0.27864123 |
| 94 | CSNK1G2 | 0.27389313 |
| 95 | SIK2 | 0.26751354 |
| 96 | SGK1 | 0.26575680 |
| 97 | PRKCZ | 0.25768954 |
| 98 | PRKCA | 0.25509264 |
| 99 | CSNK1D | 0.24304243 |
| 100 | PRKACG | 0.23887630 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.89723078 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.76761842 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.96139611 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.88078055 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.81827441 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.72744390 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.71416975 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.61667101 |
| 9 | Sulfur relay system_Homo sapiens_hsa04122 | 2.18190111 |
| 10 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 2.11197351 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.04740072 |
| 12 | Protein export_Homo sapiens_hsa03060 | 1.94837545 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.93432443 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.65782171 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.55640402 |
| 16 | Allograft rejection_Homo sapiens_hsa05330 | 1.55370391 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.54885655 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.48630103 |
| 19 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.46262485 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.45408140 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.40574888 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.38456360 |
| 23 | Proteasome_Homo sapiens_hsa03050 | 1.36164030 |
| 24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.35874364 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.29684760 |
| 26 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.28439684 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.17867424 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.14575376 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.09974061 |
| 30 | Nicotine addiction_Homo sapiens_hsa05033 | 1.08289547 |
| 31 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.02098708 |
| 32 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.98846762 |
| 33 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.92033964 |
| 34 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.89515594 |
| 35 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.86926524 |
| 36 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.82775993 |
| 37 | Base excision repair_Homo sapiens_hsa03410 | 0.79232046 |
| 38 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.79120711 |
| 39 | Phototransduction_Homo sapiens_hsa04744 | 0.78856891 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.76702885 |
| 41 | DNA replication_Homo sapiens_hsa03030 | 0.75495669 |
| 42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.75248772 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74436585 |
| 44 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.73560938 |
| 45 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.72953536 |
| 46 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67959957 |
| 47 | Spliceosome_Homo sapiens_hsa03040 | 0.67767066 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.66499358 |
| 49 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.65429710 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65386798 |
| 51 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64442649 |
| 52 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.62669601 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.62315569 |
| 54 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58614787 |
| 55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.58010516 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57561761 |
| 57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.54875215 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.54206954 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53080472 |
| 60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.52433673 |
| 61 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52210404 |
| 62 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50373370 |
| 63 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.49506902 |
| 64 | RNA transport_Homo sapiens_hsa03013 | 0.48670174 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.47615280 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45794117 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.44175007 |
| 68 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.43189120 |
| 69 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.41404812 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.41273637 |
| 71 | Leishmaniasis_Homo sapiens_hsa05140 | 0.39238952 |
| 72 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38183542 |
| 73 | Mismatch repair_Homo sapiens_hsa03430 | 0.37237972 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.35797102 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.35211920 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.34798363 |
| 77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.33792798 |
| 78 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.32021728 |
| 79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.29212483 |
| 80 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.28830788 |
| 81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.27349458 |
| 82 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.26572069 |
| 83 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26434437 |
| 84 | Peroxisome_Homo sapiens_hsa04146 | 0.26204882 |
| 85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.25729906 |
| 86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.24109744 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.23981770 |
| 88 | Morphine addiction_Homo sapiens_hsa05032 | 0.23023614 |
| 89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.22752222 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21842886 |
| 91 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.21289089 |
| 92 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.21159121 |
| 93 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.20036986 |
| 94 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.19073495 |
| 95 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.18944359 |
| 96 | Alcoholism_Homo sapiens_hsa05034 | 0.18915331 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.18206596 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16916054 |
| 99 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.16575556 |
| 100 | Insulin secretion_Homo sapiens_hsa04911 | 0.16558936 |

