

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 9.22663761 |
| 2 | translational termination (GO:0006415) | 8.79550012 |
| 3 | ribosomal small subunit biogenesis (GO:0042274) | 8.47207488 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 8.13425119 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 7.48687198 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 7.35958843 |
| 7 | protein targeting to ER (GO:0045047) | 7.34666861 |
| 8 | translational elongation (GO:0006414) | 7.33326998 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 7.24688091 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 7.02669117 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 6.86234722 |
| 12 | viral life cycle (GO:0019058) | 6.67171893 |
| 13 | cellular protein complex disassembly (GO:0043624) | 6.53938087 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.31056299 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 5.74125076 |
| 16 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.74125076 |
| 17 | translational initiation (GO:0006413) | 5.72871638 |
| 18 | behavioral response to nicotine (GO:0035095) | 5.68896861 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 5.61447599 |
| 20 | protein complex disassembly (GO:0043241) | 5.48832772 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.47440817 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 5.34884001 |
| 23 | macromolecular complex disassembly (GO:0032984) | 5.15237500 |
| 24 | protein targeting to membrane (GO:0006612) | 4.85732063 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.79580473 |
| 26 | translation (GO:0006412) | 4.62626190 |
| 27 | positive regulation of prostaglandin secretion (GO:0032308) | 4.60650978 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.48749633 |
| 29 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.41841988 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.34747343 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 4.34747343 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.34747343 |
| 33 | electron transport chain (GO:0022900) | 4.27963032 |
| 34 | respiratory electron transport chain (GO:0022904) | 4.24523712 |
| 35 | mRNA catabolic process (GO:0006402) | 4.16030305 |
| 36 | protein neddylation (GO:0045116) | 4.15652192 |
| 37 | protein complex biogenesis (GO:0070271) | 4.13222276 |
| 38 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.12759182 |
| 39 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.10869051 |
| 40 | cellular component biogenesis (GO:0044085) | 3.89560513 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.87727873 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.75929803 |
| 43 | RNA catabolic process (GO:0006401) | 3.69151795 |
| 44 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.61231078 |
| 45 | regulation of prostaglandin secretion (GO:0032306) | 3.61215898 |
| 46 | DNA deamination (GO:0045006) | 3.60484910 |
| 47 | nonmotile primary cilium assembly (GO:0035058) | 3.50044646 |
| 48 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.43644959 |
| 49 | positive regulation of icosanoid secretion (GO:0032305) | 3.41194396 |
| 50 | positive regulation of fatty acid transport (GO:2000193) | 3.39751127 |
| 51 | ATP biosynthetic process (GO:0006754) | 3.37435831 |
| 52 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.30153199 |
| 53 | establishment of protein localization to membrane (GO:0090150) | 3.28564497 |
| 54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.27028146 |
| 55 | protein targeting (GO:0006605) | 3.23102699 |
| 56 | peptidyl-histidine modification (GO:0018202) | 3.21192536 |
| 57 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.20632143 |
| 58 | rRNA processing (GO:0006364) | 3.14996051 |
| 59 | establishment of protein localization to organelle (GO:0072594) | 3.07938964 |
| 60 | GTP biosynthetic process (GO:0006183) | 3.07091531 |
| 61 | rRNA metabolic process (GO:0016072) | 3.05357867 |
| 62 | respiratory chain complex IV assembly (GO:0008535) | 2.99994622 |
| 63 | hydrogen ion transmembrane transport (GO:1902600) | 2.97393357 |
| 64 | protein targeting to mitochondrion (GO:0006626) | 2.93671254 |
| 65 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.89895119 |
| 66 | establishment of protein localization to mitochondrion (GO:0072655) | 2.83888136 |
| 67 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.82105791 |
| 68 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.80463964 |
| 69 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.80463964 |
| 70 | pseudouridine synthesis (GO:0001522) | 2.80385309 |
| 71 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.77116965 |
| 72 | base-excision repair, AP site formation (GO:0006285) | 2.76590824 |
| 73 | axoneme assembly (GO:0035082) | 2.72753767 |
| 74 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.69080759 |
| 75 | protein-cofactor linkage (GO:0018065) | 2.67771073 |
| 76 | regulation of appetite (GO:0032098) | 2.67299184 |
| 77 | GPI anchor biosynthetic process (GO:0006506) | 2.67190921 |
| 78 | proton transport (GO:0015992) | 2.65430822 |
| 79 | GPI anchor metabolic process (GO:0006505) | 2.65404989 |
| 80 | termination of RNA polymerase III transcription (GO:0006386) | 2.65170449 |
| 81 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.65170449 |
| 82 | intracellular protein transmembrane import (GO:0044743) | 2.64192090 |
| 83 | hydrogen transport (GO:0006818) | 2.62392258 |
| 84 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.60344685 |
| 85 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.59915768 |
| 86 | cytochrome complex assembly (GO:0017004) | 2.59787414 |
| 87 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.59484232 |
| 88 | protein localization to mitochondrion (GO:0070585) | 2.58992185 |
| 89 | tRNA processing (GO:0008033) | 2.56864780 |
| 90 | protein localization to membrane (GO:0072657) | 2.51147241 |
| 91 | positive regulation of respiratory burst (GO:0060267) | 2.50596020 |
| 92 | protein polyglutamylation (GO:0018095) | 2.50341029 |
| 93 | UTP biosynthetic process (GO:0006228) | 2.47112400 |
| 94 | ncRNA 3-end processing (GO:0043628) | 2.45327562 |
| 95 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.43477036 |
| 96 | metallo-sulfur cluster assembly (GO:0031163) | 2.42692705 |
| 97 | iron-sulfur cluster assembly (GO:0016226) | 2.42692705 |
| 98 | synaptic transmission, cholinergic (GO:0007271) | 2.41883930 |
| 99 | piRNA metabolic process (GO:0034587) | 2.41225217 |
| 100 | positive regulation of protein homooligomerization (GO:0032464) | 2.41051095 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.81413912 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.82528283 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.57839004 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.29880292 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.19552375 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.98603228 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.96812555 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.73564045 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.45769508 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.44272740 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.43234106 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.39506003 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.36565370 |
| 14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.28761250 |
| 15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.23551633 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.02040530 |
| 17 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.94296567 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.89764520 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.86377680 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.83887630 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.83737722 |
| 22 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.82602539 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.81409502 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.76759003 |
| 25 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.72906489 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.66512124 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.61625684 |
| 28 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59536422 |
| 29 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.57473593 |
| 30 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.54526378 |
| 31 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.54143871 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.47727055 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.47344385 |
| 34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.44287361 |
| 35 | NCOR_22424771_ChIP-Seq_293T_Human | 1.42751861 |
| 36 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.41436702 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.40192435 |
| 38 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.35286901 |
| 39 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.34683505 |
| 40 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.34649973 |
| 41 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.30974204 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.30769501 |
| 43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.30209773 |
| 44 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26274767 |
| 45 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26274767 |
| 46 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.26086444 |
| 47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.25640841 |
| 48 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.25597649 |
| 49 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.24467927 |
| 50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.23503979 |
| 51 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.21122187 |
| 52 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.20576154 |
| 53 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.19205439 |
| 54 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.16724873 |
| 55 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16474508 |
| 56 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16343781 |
| 57 | AR_20517297_ChIP-Seq_VCAP_Human | 1.16176912 |
| 58 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.15238859 |
| 59 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.13560394 |
| 60 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.13526072 |
| 61 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.13205554 |
| 62 | ERA_21632823_ChIP-Seq_H3396_Human | 1.11905987 |
| 63 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.09974479 |
| 64 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.09144290 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09067048 |
| 66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.08620960 |
| 67 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.07814901 |
| 68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07235725 |
| 69 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.06642924 |
| 70 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.05662244 |
| 71 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.05619574 |
| 72 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.05033654 |
| 73 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.04466602 |
| 74 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04159944 |
| 75 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.03618566 |
| 76 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.03577292 |
| 77 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03109246 |
| 78 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.02983514 |
| 79 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00565199 |
| 80 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.00538089 |
| 81 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.97254736 |
| 82 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.97075991 |
| 83 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.96865076 |
| 84 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.95617328 |
| 85 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.92767037 |
| 86 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.92767037 |
| 87 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.92590108 |
| 88 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91563726 |
| 89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88552086 |
| 90 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88092135 |
| 91 | P300_19829295_ChIP-Seq_ESCs_Human | 0.87653861 |
| 92 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.86421948 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.86321816 |
| 94 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.86190653 |
| 95 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.85055091 |
| 96 | P300_27268052_Chip-Seq_Bcells_Human | 0.84226289 |
| 97 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.84096905 |
| 98 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.84011126 |
| 99 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.84011126 |
| 100 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.83642755 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.39057297 |
| 2 | MP0006292_abnormal_olfactory_placode | 5.51946755 |
| 3 | MP0008789_abnormal_olfactory_epithelium | 2.95207584 |
| 4 | MP0003646_muscle_fatigue | 2.85443564 |
| 5 | MP0002163_abnormal_gland_morphology | 2.62705185 |
| 6 | MP0002102_abnormal_ear_morphology | 2.40061830 |
| 7 | MP0005394_taste/olfaction_phenotype | 2.26719336 |
| 8 | MP0005499_abnormal_olfactory_system | 2.26719336 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.16963625 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.15459151 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.06070506 |
| 12 | MP0004142_abnormal_muscle_tone | 1.99375170 |
| 13 | MP0003787_abnormal_imprinting | 1.91846458 |
| 14 | MP0006276_abnormal_autonomic_nervous | 1.84465092 |
| 15 | MP0003011_delayed_dark_adaptation | 1.78062144 |
| 16 | MP0006072_abnormal_retinal_apoptosis | 1.63362858 |
| 17 | MP0003122_maternal_imprinting | 1.62071744 |
| 18 | MP0005379_endocrine/exocrine_gland_phen | 1.57513257 |
| 19 | MP0005671_abnormal_response_to | 1.55967103 |
| 20 | MP0004885_abnormal_endolymph | 1.54581149 |
| 21 | MP0001293_anophthalmia | 1.53922568 |
| 22 | MP0002909_abnormal_adrenal_gland | 1.53399326 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.51442193 |
| 24 | MP0005377_hearing/vestibular/ear_phenot | 1.50353404 |
| 25 | MP0003878_abnormal_ear_physiology | 1.50353404 |
| 26 | MP0003136_yellow_coat_color | 1.48307309 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.48288192 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.44728856 |
| 29 | MP0008872_abnormal_physiological_respon | 1.44124659 |
| 30 | MP0004147_increased_porphyrin_level | 1.43936313 |
| 31 | MP0002876_abnormal_thyroid_physiology | 1.39199622 |
| 32 | MP0000631_abnormal_neuroendocrine_gland | 1.37973569 |
| 33 | MP0009046_muscle_twitch | 1.37880442 |
| 34 | MP0008875_abnormal_xenobiotic_pharmacok | 1.36183810 |
| 35 | MP0002160_abnormal_reproductive_system | 1.35664208 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.35203554 |
| 37 | MP0000049_abnormal_middle_ear | 1.34706418 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.32978568 |
| 39 | MP0002938_white_spotting | 1.32225061 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.31830528 |
| 41 | MP0005389_reproductive_system_phenotype | 1.31644775 |
| 42 | MP0001905_abnormal_dopamine_level | 1.31239267 |
| 43 | MP0002138_abnormal_hepatobiliary_system | 1.26953161 |
| 44 | MP0002736_abnormal_nociception_after | 1.26412171 |
| 45 | MP0003121_genomic_imprinting | 1.23964142 |
| 46 | MP0001529_abnormal_vocalization | 1.23304155 |
| 47 | MP0002277_abnormal_respiratory_mucosa | 1.22814657 |
| 48 | MP0003123_paternal_imprinting | 1.20602617 |
| 49 | MP0009745_abnormal_behavioral_response | 1.19986094 |
| 50 | MP0010386_abnormal_urinary_bladder | 1.18135672 |
| 51 | MP0009333_abnormal_splenocyte_physiolog | 1.13717236 |
| 52 | MP0008775_abnormal_heart_ventricle | 1.13571713 |
| 53 | MP0002638_abnormal_pupillary_reflex | 1.12103496 |
| 54 | MP0003879_abnormal_hair_cell | 1.11143949 |
| 55 | MP0001919_abnormal_reproductive_system | 1.06568777 |
| 56 | MP0000372_irregular_coat_pigmentation | 1.05156562 |
| 57 | MP0008995_early_reproductive_senescence | 1.04232845 |
| 58 | MP0002272_abnormal_nervous_system | 1.03828959 |
| 59 | MP0003880_abnormal_central_pattern | 1.01756812 |
| 60 | MP0004742_abnormal_vestibular_system | 1.00460675 |
| 61 | MP0005253_abnormal_eye_physiology | 0.98581603 |
| 62 | MP0005174_abnormal_tail_pigmentation | 0.98390035 |
| 63 | MP0000026_abnormal_inner_ear | 0.97803489 |
| 64 | MP0002233_abnormal_nose_morphology | 0.94972067 |
| 65 | MP0003186_abnormal_redox_activity | 0.94885005 |
| 66 | MP0003195_calcinosis | 0.92898482 |
| 67 | MP0002557_abnormal_social/conspecific_i | 0.92175377 |
| 68 | MP0003806_abnormal_nucleotide_metabolis | 0.91867957 |
| 69 | MP0001963_abnormal_hearing_physiology | 0.89365121 |
| 70 | MP0000230_abnormal_systemic_arterial | 0.86812816 |
| 71 | MP0006036_abnormal_mitochondrial_physio | 0.86066667 |
| 72 | MP0001440_abnormal_grooming_behavior | 0.85835448 |
| 73 | MP0001324_abnormal_eye_pigmentation | 0.85811267 |
| 74 | MP0002653_abnormal_ependyma_morphology | 0.84744279 |
| 75 | MP0002210_abnormal_sex_determination | 0.84110575 |
| 76 | MP0005195_abnormal_posterior_eye | 0.81714380 |
| 77 | MP0003283_abnormal_digestive_organ | 0.81367944 |
| 78 | MP0003938_abnormal_ear_development | 0.80950816 |
| 79 | MP0004145_abnormal_muscle_electrophysio | 0.80845808 |
| 80 | MP0001486_abnormal_startle_reflex | 0.80816664 |
| 81 | MP0002733_abnormal_thermal_nociception | 0.80007647 |
| 82 | MP0002234_abnormal_pharynx_morphology | 0.77199114 |
| 83 | MP0001970_abnormal_pain_threshold | 0.76668298 |
| 84 | MP0001800_abnormal_humoral_immune | 0.76407998 |
| 85 | MP0003567_abnormal_fetal_cardiomyocyte | 0.75268519 |
| 86 | MP0003786_premature_aging | 0.75052388 |
| 87 | MP0003693_abnormal_embryo_hatching | 0.74876987 |
| 88 | MP0002752_abnormal_somatic_nervous | 0.69892761 |
| 89 | MP0001929_abnormal_gametogenesis | 0.68042141 |
| 90 | MP0000778_abnormal_nervous_system | 0.67897774 |
| 91 | MP0001835_abnormal_antigen_presentation | 0.66367765 |
| 92 | MP0001765_abnormal_ion_homeostasis | 0.65427097 |
| 93 | MP0003937_abnormal_limbs/digits/tail_de | 0.65289284 |
| 94 | MP0001501_abnormal_sleep_pattern | 0.62760573 |
| 95 | MP0002184_abnormal_innervation | 0.61711268 |
| 96 | MP0000653_abnormal_sex_gland | 0.60074747 |
| 97 | MP0003638_abnormal_response/metabolism_ | 0.59647526 |
| 98 | MP0005391_vision/eye_phenotype | 0.59572947 |
| 99 | MP0010030_abnormal_orbit_morphology | 0.59437265 |
| 100 | MP0004924_abnormal_behavior | 0.58982346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.31624815 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.10556649 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.52888368 |
| 4 | Macrocytic anemia (HP:0001972) | 4.38786332 |
| 5 | Abnormal number of erythroid precursors (HP:0012131) | 4.38619530 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.95762519 |
| 7 | Acute encephalopathy (HP:0006846) | 3.92393805 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.88818153 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.74063192 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.72303608 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.67493064 |
| 12 | Pallor (HP:0000980) | 3.66693092 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.66343979 |
| 14 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.57079959 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.40618483 |
| 16 | Increased CSF lactate (HP:0002490) | 3.39101187 |
| 17 | Congenital stationary night blindness (HP:0007642) | 3.27086449 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.24962330 |
| 19 | Increased muscle lipid content (HP:0009058) | 3.21333200 |
| 20 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.19210774 |
| 21 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.19210774 |
| 22 | Abnormality of midbrain morphology (HP:0002418) | 3.16090873 |
| 23 | Molar tooth sign on MRI (HP:0002419) | 3.16090873 |
| 24 | Pancreatic cysts (HP:0001737) | 3.04696822 |
| 25 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.96689865 |
| 26 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.86247269 |
| 27 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.78378103 |
| 28 | Absent thumb (HP:0009777) | 2.77266401 |
| 29 | Cerebral edema (HP:0002181) | 2.74820503 |
| 30 | Septo-optic dysplasia (HP:0100842) | 2.71696993 |
| 31 | Abnormal ciliary motility (HP:0012262) | 2.66234689 |
| 32 | Pendular nystagmus (HP:0012043) | 2.62567526 |
| 33 | Nephronophthisis (HP:0000090) | 2.58150806 |
| 34 | Pancreatic fibrosis (HP:0100732) | 2.57757551 |
| 35 | Hepatocellular necrosis (HP:0001404) | 2.55150897 |
| 36 | Colon cancer (HP:0003003) | 2.54606091 |
| 37 | Exertional dyspnea (HP:0002875) | 2.48751157 |
| 38 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.42056208 |
| 39 | Exercise intolerance (HP:0003546) | 2.40358195 |
| 40 | Maternal diabetes (HP:0009800) | 2.40267565 |
| 41 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.40015245 |
| 42 | Hypoplasia of the fovea (HP:0007750) | 2.39559501 |
| 43 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.39559501 |
| 44 | True hermaphroditism (HP:0010459) | 2.38939712 |
| 45 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.36037760 |
| 46 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.36037760 |
| 47 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.35918846 |
| 48 | Asplenia (HP:0001746) | 2.33833896 |
| 49 | Congenital, generalized hypertrichosis (HP:0004540) | 2.32633974 |
| 50 | Concave nail (HP:0001598) | 2.32219905 |
| 51 | Abnormality of renal resorption (HP:0011038) | 2.32145806 |
| 52 | Medial flaring of the eyebrow (HP:0010747) | 2.30051394 |
| 53 | Lactic acidosis (HP:0003128) | 2.28246373 |
| 54 | Hepatic necrosis (HP:0002605) | 2.23248780 |
| 55 | Hyperglycinemia (HP:0002154) | 2.22915273 |
| 56 | Abnormal hemoglobin (HP:0011902) | 2.19516115 |
| 57 | Increased serum lactate (HP:0002151) | 2.19163372 |
| 58 | Tubular atrophy (HP:0000092) | 2.15475040 |
| 59 | Stenosis of the external auditory canal (HP:0000402) | 2.15402364 |
| 60 | Optic disc pallor (HP:0000543) | 2.14698508 |
| 61 | Severe visual impairment (HP:0001141) | 2.09815868 |
| 62 | Respiratory difficulties (HP:0002880) | 2.08654893 |
| 63 | Abnormality of the renal cortex (HP:0011035) | 2.08550303 |
| 64 | Abnormality of the renal medulla (HP:0100957) | 2.07883189 |
| 65 | Rib fusion (HP:0000902) | 2.04383328 |
| 66 | Sclerocornea (HP:0000647) | 2.02741162 |
| 67 | Anencephaly (HP:0002323) | 2.01942681 |
| 68 | Glycosuria (HP:0003076) | 2.00783475 |
| 69 | Abnormality of urine glucose concentration (HP:0011016) | 2.00783475 |
| 70 | Respiratory failure (HP:0002878) | 2.00618898 |
| 71 | Abnormal drinking behavior (HP:0030082) | 1.99555222 |
| 72 | Polydipsia (HP:0001959) | 1.99555222 |
| 73 | Optic nerve hypoplasia (HP:0000609) | 1.96491351 |
| 74 | Depressed nasal ridge (HP:0000457) | 1.93948110 |
| 75 | Hyperthyroidism (HP:0000836) | 1.92687523 |
| 76 | Stomatitis (HP:0010280) | 1.91073217 |
| 77 | Abnormality of the fovea (HP:0000493) | 1.88372617 |
| 78 | Leukodystrophy (HP:0002415) | 1.88177075 |
| 79 | Chronic hepatic failure (HP:0100626) | 1.88109225 |
| 80 | Lethargy (HP:0001254) | 1.86834611 |
| 81 | Myokymia (HP:0002411) | 1.86270163 |
| 82 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.84737094 |
| 83 | Microretrognathia (HP:0000308) | 1.83950970 |
| 84 | Type II lissencephaly (HP:0007260) | 1.82981178 |
| 85 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.82655621 |
| 86 | Anophthalmia (HP:0000528) | 1.82504361 |
| 87 | Chronic sinusitis (HP:0011109) | 1.82468751 |
| 88 | Abolished electroretinogram (ERG) (HP:0000550) | 1.79126915 |
| 89 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.78566716 |
| 90 | Hypoplasia of the ulna (HP:0003022) | 1.76549853 |
| 91 | Hypoplasia of the radius (HP:0002984) | 1.76449242 |
| 92 | Abnormality of macular pigmentation (HP:0008002) | 1.74135927 |
| 93 | Abnormal pupillary function (HP:0007686) | 1.73422064 |
| 94 | Abnormality of DNA repair (HP:0003254) | 1.73185059 |
| 95 | IgG deficiency (HP:0004315) | 1.73100312 |
| 96 | Rhinitis (HP:0012384) | 1.72566209 |
| 97 | Gait imbalance (HP:0002141) | 1.71806541 |
| 98 | Triphalangeal thumb (HP:0001199) | 1.71338841 |
| 99 | Median cleft lip (HP:0000161) | 1.70182811 |
| 100 | Congenital primary aphakia (HP:0007707) | 1.69473626 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 3.53440093 |
| 2 | STK16 | 3.24998974 |
| 3 | WNK4 | 2.77570046 |
| 4 | GRK1 | 2.66026927 |
| 5 | FRK | 2.58864932 |
| 6 | TAOK3 | 2.57365515 |
| 7 | STK39 | 2.53898446 |
| 8 | DYRK2 | 2.46773782 |
| 9 | MAP4K2 | 2.45888764 |
| 10 | TLK1 | 2.29168569 |
| 11 | MAP2K2 | 2.21173411 |
| 12 | ZAK | 2.18689999 |
| 13 | BCKDK | 1.97270319 |
| 14 | NME2 | 1.93605865 |
| 15 | CDK19 | 1.88174245 |
| 16 | PIK3CA | 1.76317680 |
| 17 | NUAK1 | 1.69912625 |
| 18 | CDC7 | 1.68437298 |
| 19 | LRRK2 | 1.60759654 |
| 20 | TXK | 1.45962107 |
| 21 | PINK1 | 1.44329737 |
| 22 | TIE1 | 1.41283482 |
| 23 | MST4 | 1.39330796 |
| 24 | OXSR1 | 1.32119123 |
| 25 | ABL2 | 1.32104049 |
| 26 | MUSK | 1.30244822 |
| 27 | TEC | 1.23339013 |
| 28 | MAP3K11 | 1.16331497 |
| 29 | MAPK13 | 1.13284557 |
| 30 | ADRBK1 | 1.12555433 |
| 31 | DYRK1A | 1.09919526 |
| 32 | LIMK1 | 0.99066693 |
| 33 | BMPR1B | 0.97630038 |
| 34 | PAK3 | 0.97101825 |
| 35 | INSRR | 0.96645587 |
| 36 | WNK3 | 0.94817023 |
| 37 | MAP4K1 | 0.94471989 |
| 38 | MKNK2 | 0.93721746 |
| 39 | RPS6KA5 | 0.93670719 |
| 40 | IKBKB | 0.91165783 |
| 41 | NTRK3 | 0.89398404 |
| 42 | TNIK | 0.87736005 |
| 43 | MAP3K4 | 0.85972127 |
| 44 | TNK2 | 0.84867103 |
| 45 | CDK8 | 0.84253993 |
| 46 | DYRK3 | 0.83697149 |
| 47 | CSNK2A2 | 0.83161127 |
| 48 | PDK2 | 0.81411376 |
| 49 | PRKCG | 0.79353016 |
| 50 | CAMK1 | 0.77955614 |
| 51 | EPHA4 | 0.77617491 |
| 52 | STK38L | 0.76407821 |
| 53 | PRKCQ | 0.74563827 |
| 54 | PRKACA | 0.72227556 |
| 55 | MAP2K1 | 0.71973511 |
| 56 | AURKB | 0.69414149 |
| 57 | PRKCI | 0.69102869 |
| 58 | MAP2K6 | 0.68675888 |
| 59 | CAMKK2 | 0.63819500 |
| 60 | CSNK2A1 | 0.62609328 |
| 61 | PHKG1 | 0.60202926 |
| 62 | PHKG2 | 0.60202926 |
| 63 | DAPK3 | 0.59822877 |
| 64 | OBSCN | 0.59695878 |
| 65 | ITK | 0.58805071 |
| 66 | LYN | 0.58730022 |
| 67 | SYK | 0.58212488 |
| 68 | GRK6 | 0.58130414 |
| 69 | DAPK2 | 0.57032027 |
| 70 | ERBB2 | 0.53838766 |
| 71 | PLK4 | 0.53567124 |
| 72 | IKBKE | 0.52137062 |
| 73 | PIM1 | 0.51998062 |
| 74 | CASK | 0.51152038 |
| 75 | STK11 | 0.50516060 |
| 76 | GRK5 | 0.49849179 |
| 77 | ATR | 0.49512618 |
| 78 | CDC42BPA | 0.49335275 |
| 79 | SRPK1 | 0.48460638 |
| 80 | EPHB2 | 0.47621147 |
| 81 | BTK | 0.47563650 |
| 82 | CSNK1E | 0.47349334 |
| 83 | MARK3 | 0.47254814 |
| 84 | CSNK1A1 | 0.45917056 |
| 85 | PLK1 | 0.45448144 |
| 86 | PRKCA | 0.45324488 |
| 87 | ABL1 | 0.45081998 |
| 88 | PRKD2 | 0.44388298 |
| 89 | AURKA | 0.43520756 |
| 90 | RPS6KA6 | 0.43332561 |
| 91 | CHEK2 | 0.41662740 |
| 92 | NEK1 | 0.40653846 |
| 93 | KIT | 0.40207978 |
| 94 | FES | 0.40199624 |
| 95 | PRKCZ | 0.38343797 |
| 96 | NTRK2 | 0.37970794 |
| 97 | CLK1 | 0.37686349 |
| 98 | VRK1 | 0.36756429 |
| 99 | SGK1 | 0.35892755 |
| 100 | CAMK2A | 0.34549697 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.04699023 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.13131686 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.50903201 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.59140471 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48955462 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.43161657 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.37644489 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.29552361 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.27747212 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.26168273 |
| 11 | Sulfur relay system_Homo sapiens_hsa04122 | 2.20460180 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.04062633 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.97478424 |
| 14 | Allograft rejection_Homo sapiens_hsa05330 | 1.92062930 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.91414925 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.82157087 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67740249 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.64584955 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.62411003 |
| 20 | Proteasome_Homo sapiens_hsa03050 | 1.62140832 |
| 21 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.47390075 |
| 22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.46249962 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.42278889 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.39987542 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.30823843 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.29372333 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.20814527 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.17982064 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.17531288 |
| 30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.07677182 |
| 31 | DNA replication_Homo sapiens_hsa03030 | 1.07007217 |
| 32 | Olfactory transduction_Homo sapiens_hsa04740 | 1.03798952 |
| 33 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.02968678 |
| 34 | Basal transcription factors_Homo sapiens_hsa03022 | 1.00125183 |
| 35 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.00088008 |
| 36 | Nicotine addiction_Homo sapiens_hsa05033 | 0.99303751 |
| 37 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.97429483 |
| 38 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.97265331 |
| 39 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96964268 |
| 40 | Mismatch repair_Homo sapiens_hsa03430 | 0.96823363 |
| 41 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.93355865 |
| 42 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.90384024 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89943599 |
| 44 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88040921 |
| 45 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.87504258 |
| 46 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85862486 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.84720460 |
| 48 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.84633843 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.83332776 |
| 50 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.82023755 |
| 51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.80862018 |
| 52 | Spliceosome_Homo sapiens_hsa03040 | 0.80372299 |
| 53 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.80249763 |
| 54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.80177817 |
| 55 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.79626055 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75490071 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.73311815 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.72524933 |
| 59 | Morphine addiction_Homo sapiens_hsa05032 | 0.71618194 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68554898 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67190782 |
| 62 | Peroxisome_Homo sapiens_hsa04146 | 0.64144394 |
| 63 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.60676263 |
| 64 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59947844 |
| 65 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59819596 |
| 66 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.59742933 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59733587 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.57158574 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56331817 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55736537 |
| 71 | Base excision repair_Homo sapiens_hsa03410 | 0.55663601 |
| 72 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54759559 |
| 73 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.52493090 |
| 74 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52111543 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49734943 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49110044 |
| 77 | RNA transport_Homo sapiens_hsa03013 | 0.48610245 |
| 78 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44504850 |
| 79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41928128 |
| 80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.41406234 |
| 81 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.37537684 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.37112808 |
| 83 | Viral myocarditis_Homo sapiens_hsa05416 | 0.34877183 |
| 84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.34572549 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34467674 |
| 86 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.32591488 |
| 87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32420921 |
| 88 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30826808 |
| 89 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.29620633 |
| 90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.29396467 |
| 91 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.29338873 |
| 92 | Insulin secretion_Homo sapiens_hsa04911 | 0.28963932 |
| 93 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.27975897 |
| 94 | GABAergic synapse_Homo sapiens_hsa04727 | 0.25224273 |
| 95 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.25098656 |
| 96 | Taste transduction_Homo sapiens_hsa04742 | 0.21802644 |
| 97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.21440856 |
| 98 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.19864146 |
| 99 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.18384551 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.16155203 |

