

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit biogenesis (GO:0042274) | 7.54118240 |
| 2 | viral transcription (GO:0019083) | 7.08981598 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 6.88834992 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 6.85035304 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.85035304 |
| 6 | translational termination (GO:0006415) | 6.75166019 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 6.63869615 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.61076026 |
| 9 | maturation of SSU-rRNA (GO:0030490) | 6.23467759 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.89613726 |
| 11 | translational elongation (GO:0006414) | 5.89569104 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.78977645 |
| 13 | cotranslational protein targeting to membrane (GO:0006613) | 5.78533072 |
| 14 | protein targeting to ER (GO:0045047) | 5.74991818 |
| 15 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.49264537 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 5.43360971 |
| 17 | respiratory electron transport chain (GO:0022904) | 5.30556669 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.30235619 |
| 19 | electron transport chain (GO:0022900) | 5.20326662 |
| 20 | cellular protein complex disassembly (GO:0043624) | 5.13872290 |
| 21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.13538188 |
| 22 | NADH dehydrogenase complex assembly (GO:0010257) | 5.13538188 |
| 23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.13538188 |
| 24 | viral life cycle (GO:0019058) | 5.00157713 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.94108777 |
| 26 | translational initiation (GO:0006413) | 4.75734901 |
| 27 | protein complex biogenesis (GO:0070271) | 4.72378889 |
| 28 | DNA deamination (GO:0045006) | 4.67997186 |
| 29 | rRNA modification (GO:0000154) | 4.51072251 |
| 30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.50304936 |
| 31 | translation (GO:0006412) | 4.49139670 |
| 32 | pseudouridine synthesis (GO:0001522) | 4.40191261 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 4.25517520 |
| 34 | protein complex disassembly (GO:0043241) | 4.24600730 |
| 35 | ATP biosynthetic process (GO:0006754) | 4.21862247 |
| 36 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.12786054 |
| 37 | respiratory chain complex IV assembly (GO:0008535) | 4.11923495 |
| 38 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.10653232 |
| 39 | proteasome assembly (GO:0043248) | 4.10243412 |
| 40 | ncRNA 3-end processing (GO:0043628) | 4.05914778 |
| 41 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.05625238 |
| 42 | macromolecular complex disassembly (GO:0032984) | 4.01661903 |
| 43 | protein neddylation (GO:0045116) | 3.99429155 |
| 44 | cellular component biogenesis (GO:0044085) | 3.98209384 |
| 45 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.97198064 |
| 46 | protein targeting to mitochondrion (GO:0006626) | 3.96811562 |
| 47 | protein targeting to membrane (GO:0006612) | 3.89688565 |
| 48 | protein-cofactor linkage (GO:0018065) | 3.79136352 |
| 49 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.75797266 |
| 50 | GTP biosynthetic process (GO:0006183) | 3.75158016 |
| 51 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.71438853 |
| 52 | establishment of protein localization to mitochondrion (GO:0072655) | 3.68728635 |
| 53 | rRNA processing (GO:0006364) | 3.68717456 |
| 54 | termination of RNA polymerase III transcription (GO:0006386) | 3.60704270 |
| 55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.60704270 |
| 56 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.59917767 |
| 57 | hydrogen ion transmembrane transport (GO:1902600) | 3.58579083 |
| 58 | peptidyl-histidine modification (GO:0018202) | 3.56600132 |
| 59 | rRNA metabolic process (GO:0016072) | 3.56366477 |
| 60 | cytochrome complex assembly (GO:0017004) | 3.55063480 |
| 61 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.51476803 |
| 62 | mRNA catabolic process (GO:0006402) | 3.49645061 |
| 63 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.47057843 |
| 64 | regulation of mitochondrial translation (GO:0070129) | 3.46436462 |
| 65 | intracellular protein transmembrane import (GO:0044743) | 3.46199349 |
| 66 | protein localization to mitochondrion (GO:0070585) | 3.43409248 |
| 67 | rRNA methylation (GO:0031167) | 3.32897275 |
| 68 | UTP biosynthetic process (GO:0006228) | 3.32860934 |
| 69 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.26123285 |
| 70 | mitochondrial transport (GO:0006839) | 3.26042738 |
| 71 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.24555542 |
| 72 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.23897789 |
| 73 | behavioral response to nicotine (GO:0035095) | 3.20055301 |
| 74 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.18691260 |
| 75 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.18691260 |
| 76 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.17954561 |
| 77 | proton transport (GO:0015992) | 3.17020713 |
| 78 | spliceosomal snRNP assembly (GO:0000387) | 3.16930303 |
| 79 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.13517304 |
| 80 | RNA catabolic process (GO:0006401) | 3.12503420 |
| 81 | DNA replication checkpoint (GO:0000076) | 3.12119973 |
| 82 | hydrogen transport (GO:0006818) | 3.09499691 |
| 83 | UTP metabolic process (GO:0046051) | 3.07656912 |
| 84 | positive regulation of prostaglandin secretion (GO:0032308) | 2.96175690 |
| 85 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.93349008 |
| 86 | DNA damage response, detection of DNA damage (GO:0042769) | 2.89788942 |
| 87 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.89141000 |
| 88 | gonadal mesoderm development (GO:0007506) | 2.84989360 |
| 89 | protein targeting (GO:0006605) | 2.83975533 |
| 90 | tRNA processing (GO:0008033) | 2.83437921 |
| 91 | ubiquinone biosynthetic process (GO:0006744) | 2.82095686 |
| 92 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.81970244 |
| 93 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.81970244 |
| 94 | protein transmembrane transport (GO:0071806) | 2.79714905 |
| 95 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.77794458 |
| 96 | oxidative phosphorylation (GO:0006119) | 2.77053448 |
| 97 | ncRNA processing (GO:0034470) | 2.75230579 |
| 98 | ribosome biogenesis (GO:0042254) | 2.66159392 |
| 99 | positive regulation of fatty acid transport (GO:2000193) | 2.65627422 |
| 100 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.63671897 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.32572217 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21270266 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.95074126 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.68653787 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.51773754 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.47005874 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.34364573 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.33547496 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.33476708 |
| 10 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.29949600 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.77642381 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.71407904 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.49955048 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.48467557 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.43959944 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.27222854 |
| 17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.26324132 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.16973234 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.04353362 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93504234 |
| 21 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.93123109 |
| 22 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.91908268 |
| 23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.91831601 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.89836515 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.86653218 |
| 26 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.83578933 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.80681357 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.80616071 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.77483910 |
| 30 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.73107312 |
| 31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.71990708 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.69567996 |
| 33 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.69405689 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.68488693 |
| 35 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.65722013 |
| 36 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.61246464 |
| 37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.57664267 |
| 38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.57081345 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.52729278 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.52728721 |
| 41 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.48561022 |
| 42 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.43267785 |
| 43 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.39636071 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34135853 |
| 45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.33627324 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.33293568 |
| 47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.32933321 |
| 48 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32826133 |
| 49 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.32580824 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.32256509 |
| 51 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.31885946 |
| 52 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.26846342 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24539577 |
| 54 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.23269438 |
| 55 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.22877374 |
| 56 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.19876293 |
| 57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18590172 |
| 58 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14257694 |
| 59 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.13987968 |
| 60 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.13784683 |
| 61 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.12899389 |
| 62 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.12196670 |
| 63 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11040738 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.09883098 |
| 65 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08650580 |
| 66 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.07985168 |
| 67 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.04453568 |
| 68 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.02619813 |
| 69 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.01139521 |
| 70 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.00974774 |
| 71 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00319523 |
| 72 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.99454494 |
| 73 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98400640 |
| 74 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97613369 |
| 75 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.96559752 |
| 76 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.95605675 |
| 77 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95188406 |
| 78 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94164970 |
| 79 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.93944682 |
| 80 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.89635042 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89419448 |
| 82 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88969367 |
| 83 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88945248 |
| 84 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88753239 |
| 85 | P300_19829295_ChIP-Seq_ESCs_Human | 0.85578862 |
| 86 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.85430855 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.84991901 |
| 88 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.84343245 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.83839303 |
| 90 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.83525957 |
| 91 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.83502202 |
| 92 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83494562 |
| 93 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83494562 |
| 94 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.82340062 |
| 95 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.82203801 |
| 96 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.81911478 |
| 97 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81471101 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.81179124 |
| 99 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.81175862 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.81135731 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.69474035 |
| 2 | MP0002163_abnormal_gland_morphology | 4.37201875 |
| 3 | MP0005646_abnormal_pituitary_gland | 3.20869273 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.14804023 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.83981227 |
| 6 | MP0005379_endocrine/exocrine_gland_phen | 2.60378541 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.37953052 |
| 8 | MP0004142_abnormal_muscle_tone | 2.17641487 |
| 9 | MP0004147_increased_porphyrin_level | 2.15491882 |
| 10 | MP0001188_hyperpigmentation | 2.11649037 |
| 11 | MP0003011_delayed_dark_adaptation | 2.10338609 |
| 12 | MP0006276_abnormal_autonomic_nervous | 2.08310350 |
| 13 | MP0004885_abnormal_endolymph | 1.96755488 |
| 14 | MP0000372_irregular_coat_pigmentation | 1.91903681 |
| 15 | MP0005187_abnormal_penis_morphology | 1.88649224 |
| 16 | MP0003136_yellow_coat_color | 1.70830890 |
| 17 | MP0005253_abnormal_eye_physiology | 1.68922383 |
| 18 | MP0003693_abnormal_embryo_hatching | 1.64577957 |
| 19 | MP0002736_abnormal_nociception_after | 1.58689971 |
| 20 | MP0002277_abnormal_respiratory_mucosa | 1.58394242 |
| 21 | MP0003646_muscle_fatigue | 1.56860794 |
| 22 | MP0000049_abnormal_middle_ear | 1.55936128 |
| 23 | MP0002653_abnormal_ependyma_morphology | 1.55766863 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.55706547 |
| 25 | MP0001986_abnormal_taste_sensitivity | 1.55634688 |
| 26 | MP0002876_abnormal_thyroid_physiology | 1.53044614 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.52242473 |
| 28 | MP0004215_abnormal_myocardial_fiber | 1.50191761 |
| 29 | MP0006036_abnormal_mitochondrial_physio | 1.48890919 |
| 30 | MP0002160_abnormal_reproductive_system | 1.48258754 |
| 31 | MP0003878_abnormal_ear_physiology | 1.39708529 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.39708529 |
| 33 | MP0005671_abnormal_response_to | 1.33571121 |
| 34 | MP0005389_reproductive_system_phenotype | 1.33270835 |
| 35 | MP0008872_abnormal_physiological_respon | 1.31264159 |
| 36 | MP0002272_abnormal_nervous_system | 1.28801724 |
| 37 | MP0001968_abnormal_touch/_nociception | 1.28549631 |
| 38 | MP0003186_abnormal_redox_activity | 1.28509434 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.26029949 |
| 40 | MP0003567_abnormal_fetal_cardiomyocyte | 1.25779783 |
| 41 | MP0003123_paternal_imprinting | 1.25775537 |
| 42 | MP0009046_muscle_twitch | 1.24713258 |
| 43 | MP0002234_abnormal_pharynx_morphology | 1.24088854 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.23855614 |
| 45 | MP0001919_abnormal_reproductive_system | 1.23607436 |
| 46 | MP0003806_abnormal_nucleotide_metabolis | 1.21401674 |
| 47 | MP0005423_abnormal_somatic_nervous | 1.21250434 |
| 48 | MP0009745_abnormal_behavioral_response | 1.16976215 |
| 49 | MP0000631_abnormal_neuroendocrine_gland | 1.16588968 |
| 50 | MP0002138_abnormal_hepatobiliary_system | 1.15711771 |
| 51 | MP0003283_abnormal_digestive_organ | 1.15116001 |
| 52 | MP0001905_abnormal_dopamine_level | 1.12644105 |
| 53 | MP0001485_abnormal_pinna_reflex | 1.10778612 |
| 54 | MP0002102_abnormal_ear_morphology | 1.07826117 |
| 55 | MP0003880_abnormal_central_pattern | 1.03256573 |
| 56 | MP0002127_abnormal_cardiovascular_syste | 1.02065636 |
| 57 | MP0003786_premature_aging | 1.00640203 |
| 58 | MP0001529_abnormal_vocalization | 1.00255528 |
| 59 | MP0004742_abnormal_vestibular_system | 0.99306426 |
| 60 | MP0003195_calcinosis | 0.99121167 |
| 61 | MP0006035_abnormal_mitochondrial_morpho | 0.97814582 |
| 62 | MP0008058_abnormal_DNA_repair | 0.93925581 |
| 63 | MP0004085_abnormal_heartbeat | 0.90934686 |
| 64 | MP0008877_abnormal_DNA_methylation | 0.89647676 |
| 65 | MP0010386_abnormal_urinary_bladder | 0.87979478 |
| 66 | MP0003937_abnormal_limbs/digits/tail_de | 0.87755903 |
| 67 | MP0003137_abnormal_impulse_conducting | 0.86848854 |
| 68 | MP0000678_abnormal_parathyroid_gland | 0.83947816 |
| 69 | MP0001502_abnormal_circadian_rhythm | 0.83733847 |
| 70 | MP0002938_white_spotting | 0.81305381 |
| 71 | MP0005195_abnormal_posterior_eye | 0.78807129 |
| 72 | MP0004133_heterotaxia | 0.78121981 |
| 73 | MP0003638_abnormal_response/metabolism_ | 0.75730184 |
| 74 | MP0002210_abnormal_sex_determination | 0.75431288 |
| 75 | MP0005645_abnormal_hypothalamus_physiol | 0.75358710 |
| 76 | MP0003718_maternal_effect | 0.75320631 |
| 77 | MP0001293_anophthalmia | 0.74944829 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.74351617 |
| 79 | MP0005332_abnormal_amino_acid | 0.73599811 |
| 80 | MP0000230_abnormal_systemic_arterial | 0.73265067 |
| 81 | MP0001984_abnormal_olfaction | 0.72574467 |
| 82 | MP0002184_abnormal_innervation | 0.72511479 |
| 83 | MP0003315_abnormal_perineum_morphology | 0.72365708 |
| 84 | MP0005360_urolithiasis | 0.72119506 |
| 85 | MP0002095_abnormal_skin_pigmentation | 0.70708545 |
| 86 | MP0002132_abnormal_respiratory_system | 0.70132559 |
| 87 | MP0010368_abnormal_lymphatic_system | 0.70044948 |
| 88 | MP0003724_increased_susceptibility_to | 0.69940658 |
| 89 | MP0008775_abnormal_heart_ventricle | 0.69156776 |
| 90 | MP0005391_vision/eye_phenotype | 0.68834367 |
| 91 | MP0001764_abnormal_homeostasis | 0.68465773 |
| 92 | MP0002572_abnormal_emotion/affect_behav | 0.66959158 |
| 93 | MP0008789_abnormal_olfactory_epithelium | 0.66892432 |
| 94 | MP0002752_abnormal_somatic_nervous | 0.64740379 |
| 95 | MP0002064_seizures | 0.64686961 |
| 96 | MP0005410_abnormal_fertilization | 0.62638418 |
| 97 | MP0002557_abnormal_social/conspecific_i | 0.62622020 |
| 98 | MP0001440_abnormal_grooming_behavior | 0.62582615 |
| 99 | MP0000647_abnormal_sebaceous_gland | 0.60955067 |
| 100 | MP0000653_abnormal_sex_gland | 0.60480609 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.45419008 |
| 2 | Mitochondrial inheritance (HP:0001427) | 5.09264836 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.86442441 |
| 4 | Acute encephalopathy (HP:0006846) | 4.84378452 |
| 5 | Increased CSF lactate (HP:0002490) | 4.64069339 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.60756885 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 4.45179902 |
| 8 | Progressive macrocephaly (HP:0004481) | 4.34870213 |
| 9 | Hepatocellular necrosis (HP:0001404) | 4.11144477 |
| 10 | Congenital stationary night blindness (HP:0007642) | 4.04961973 |
| 11 | Hepatic necrosis (HP:0002605) | 3.91400911 |
| 12 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.86837848 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.71887689 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.70698599 |
| 15 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.69978853 |
| 16 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.69978853 |
| 17 | Macrocytic anemia (HP:0001972) | 3.65028142 |
| 18 | Cerebral edema (HP:0002181) | 3.61752800 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 3.61187861 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 3.58116233 |
| 21 | Reticulocytopenia (HP:0001896) | 3.27075495 |
| 22 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.24758101 |
| 23 | Increased serum lactate (HP:0002151) | 3.14753342 |
| 24 | Increased muscle lipid content (HP:0009058) | 3.13952728 |
| 25 | Lactic acidosis (HP:0003128) | 3.05612303 |
| 26 | Exertional dyspnea (HP:0002875) | 3.01115063 |
| 27 | Respiratory difficulties (HP:0002880) | 2.96492541 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.96334662 |
| 29 | Concave nail (HP:0001598) | 2.89242604 |
| 30 | Respiratory failure (HP:0002878) | 2.79211058 |
| 31 | Pancreatic cysts (HP:0001737) | 2.72771010 |
| 32 | Abnormality of midbrain morphology (HP:0002418) | 2.70272299 |
| 33 | Molar tooth sign on MRI (HP:0002419) | 2.70272299 |
| 34 | Glycosuria (HP:0003076) | 2.60449165 |
| 35 | Abnormality of urine glucose concentration (HP:0011016) | 2.60449165 |
| 36 | Pallor (HP:0000980) | 2.58093085 |
| 37 | Hyperphosphaturia (HP:0003109) | 2.55131201 |
| 38 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.51877351 |
| 39 | Absent/shortened dynein arms (HP:0200106) | 2.51877351 |
| 40 | Type II lissencephaly (HP:0007260) | 2.51750717 |
| 41 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.49634594 |
| 42 | Abnormality of alanine metabolism (HP:0010916) | 2.49634594 |
| 43 | Hyperalaninemia (HP:0003348) | 2.49634594 |
| 44 | Congenital, generalized hypertrichosis (HP:0004540) | 2.48361465 |
| 45 | Optic disc pallor (HP:0000543) | 2.44657079 |
| 46 | Exercise intolerance (HP:0003546) | 2.41425241 |
| 47 | Sclerocornea (HP:0000647) | 2.37165541 |
| 48 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34338062 |
| 49 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.27951511 |
| 50 | Hyperglycinemia (HP:0002154) | 2.25008976 |
| 51 | Abnormality of renal resorption (HP:0011038) | 2.22931757 |
| 52 | Lethargy (HP:0001254) | 2.20574047 |
| 53 | Testicular atrophy (HP:0000029) | 2.17324216 |
| 54 | Leukodystrophy (HP:0002415) | 2.16182674 |
| 55 | Absent thumb (HP:0009777) | 2.13479958 |
| 56 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.13255253 |
| 57 | Hypoplasia of the uterus (HP:0000013) | 2.11608401 |
| 58 | Progressive microcephaly (HP:0000253) | 2.11301765 |
| 59 | IgG deficiency (HP:0004315) | 2.10734667 |
| 60 | Methylmalonic acidemia (HP:0002912) | 2.07872113 |
| 61 | True hermaphroditism (HP:0010459) | 2.05736127 |
| 62 | CNS demyelination (HP:0007305) | 2.04094667 |
| 63 | Abdominal situs inversus (HP:0003363) | 2.02258941 |
| 64 | Abnormality of abdominal situs (HP:0011620) | 2.02258941 |
| 65 | Methylmalonic aciduria (HP:0012120) | 2.02011895 |
| 66 | Microretrognathia (HP:0000308) | 2.01424520 |
| 67 | Type 2 muscle fiber atrophy (HP:0003554) | 1.99828967 |
| 68 | Increased serum pyruvate (HP:0003542) | 1.98083100 |
| 69 | Pancreatic fibrosis (HP:0100732) | 1.97775694 |
| 70 | Hypoplasia of the radius (HP:0002984) | 1.97152754 |
| 71 | Occipital encephalocele (HP:0002085) | 1.96949296 |
| 72 | Cleft eyelid (HP:0000625) | 1.94295429 |
| 73 | Triphalangeal thumb (HP:0001199) | 1.93356714 |
| 74 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.90905153 |
| 75 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.90394532 |
| 76 | Nephronophthisis (HP:0000090) | 1.88605843 |
| 77 | Colon cancer (HP:0003003) | 1.88025233 |
| 78 | Generalized aminoaciduria (HP:0002909) | 1.87415177 |
| 79 | Hyperglycinuria (HP:0003108) | 1.87403051 |
| 80 | Abnormal urine phosphate concentration (HP:0012599) | 1.86880185 |
| 81 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.86260081 |
| 82 | Aplastic anemia (HP:0001915) | 1.81224954 |
| 83 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.78337748 |
| 84 | Muscle fiber atrophy (HP:0100295) | 1.77244924 |
| 85 | Conical tooth (HP:0000698) | 1.76055488 |
| 86 | Pendular nystagmus (HP:0012043) | 1.75576080 |
| 87 | Abnormal hemoglobin (HP:0011902) | 1.74306815 |
| 88 | Delayed CNS myelination (HP:0002188) | 1.70085535 |
| 89 | Forearm undergrowth (HP:0009821) | 1.68435874 |
| 90 | Abnormal number of incisors (HP:0011064) | 1.65824732 |
| 91 | Absent phalangeal crease (HP:0006109) | 1.65816550 |
| 92 | Anencephaly (HP:0002323) | 1.65744905 |
| 93 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.64423878 |
| 94 | Renal cortical cysts (HP:0000803) | 1.64002849 |
| 95 | Preaxial hand polydactyly (HP:0001177) | 1.62947454 |
| 96 | X-linked dominant inheritance (HP:0001423) | 1.62645890 |
| 97 | Medial flaring of the eyebrow (HP:0010747) | 1.62273431 |
| 98 | Pancytopenia (HP:0001876) | 1.61370883 |
| 99 | Abnormality of the renal cortex (HP:0011035) | 1.60929294 |
| 100 | Abnormality of glycine metabolism (HP:0010895) | 1.60059699 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GRK1 | 4.12920400 |
| 2 | TLK1 | 4.08262225 |
| 3 | ZAK | 3.31305093 |
| 4 | NME2 | 3.27682538 |
| 5 | PDK2 | 3.23957219 |
| 6 | BCKDK | 2.73326891 |
| 7 | TAOK3 | 2.68669432 |
| 8 | VRK2 | 2.39117168 |
| 9 | ADRBK2 | 2.23741794 |
| 10 | BUB1 | 2.17456520 |
| 11 | PINK1 | 2.08299251 |
| 12 | PLK4 | 1.91414344 |
| 13 | BLK | 1.89764482 |
| 14 | NME1 | 1.69451680 |
| 15 | NUAK1 | 1.66305696 |
| 16 | DYRK2 | 1.63338851 |
| 17 | NEK1 | 1.59172637 |
| 18 | MAP4K2 | 1.57861095 |
| 19 | TXK | 1.49644881 |
| 20 | WNK4 | 1.47761393 |
| 21 | BMPR1B | 1.46460099 |
| 22 | MAP3K4 | 1.38509941 |
| 23 | VRK1 | 1.37593970 |
| 24 | IKBKB | 1.35630307 |
| 25 | TIE1 | 1.33544031 |
| 26 | PHKG2 | 1.21341317 |
| 27 | PHKG1 | 1.21341317 |
| 28 | OBSCN | 1.19030058 |
| 29 | PASK | 1.14603836 |
| 30 | MAP2K7 | 1.07947002 |
| 31 | GRK6 | 1.07194773 |
| 32 | AURKA | 1.05470461 |
| 33 | STK16 | 1.04631553 |
| 34 | SRPK1 | 1.02404487 |
| 35 | MAP2K2 | 1.01239699 |
| 36 | PRKCG | 0.98164278 |
| 37 | LRRK2 | 0.97249262 |
| 38 | CDC7 | 0.95246870 |
| 39 | MUSK | 0.92184807 |
| 40 | KDR | 0.89500963 |
| 41 | RPS6KA5 | 0.87057388 |
| 42 | MAPK13 | 0.85394603 |
| 43 | STK39 | 0.83936983 |
| 44 | TGFBR1 | 0.78420062 |
| 45 | TNIK | 0.75780888 |
| 46 | INSRR | 0.75402295 |
| 47 | STK4 | 0.74538499 |
| 48 | CSNK2A2 | 0.72604364 |
| 49 | MKNK2 | 0.71822649 |
| 50 | AURKB | 0.70503036 |
| 51 | ABL2 | 0.69817551 |
| 52 | TEC | 0.69192242 |
| 53 | MAP3K9 | 0.68080556 |
| 54 | PRKACA | 0.67140778 |
| 55 | DAPK1 | 0.66769257 |
| 56 | CHEK2 | 0.66096455 |
| 57 | NTRK2 | 0.65972365 |
| 58 | PIM1 | 0.64190991 |
| 59 | FRK | 0.63484077 |
| 60 | DYRK3 | 0.61744779 |
| 61 | TRIM28 | 0.61561191 |
| 62 | DAPK2 | 0.61074781 |
| 63 | PIK3CA | 0.60797309 |
| 64 | CAMK2A | 0.60662267 |
| 65 | IKBKE | 0.60279757 |
| 66 | CSNK2A1 | 0.60253199 |
| 67 | MYLK | 0.57591180 |
| 68 | PAK3 | 0.57562464 |
| 69 | PIM2 | 0.57500503 |
| 70 | ILK | 0.56938574 |
| 71 | PLK1 | 0.56926296 |
| 72 | CSNK1G1 | 0.56620625 |
| 73 | CSNK1G2 | 0.56598197 |
| 74 | RPS6KA4 | 0.56394722 |
| 75 | CSNK1G3 | 0.55678205 |
| 76 | EIF2AK2 | 0.55152316 |
| 77 | CDK19 | 0.55047765 |
| 78 | LIMK1 | 0.54803290 |
| 79 | RPS6KA6 | 0.54217555 |
| 80 | ADRBK1 | 0.54111151 |
| 81 | PRKCI | 0.53903572 |
| 82 | GRK7 | 0.53241525 |
| 83 | TSSK6 | 0.52324320 |
| 84 | CAMK1 | 0.51190581 |
| 85 | CAMKK2 | 0.51178706 |
| 86 | PRKCQ | 0.50837071 |
| 87 | ARAF | 0.50705353 |
| 88 | MAPKAPK3 | 0.50637182 |
| 89 | WNK3 | 0.50074940 |
| 90 | MAP3K12 | 0.49717372 |
| 91 | CDK8 | 0.49178600 |
| 92 | CSNK1A1 | 0.48836482 |
| 93 | MKNK1 | 0.48328739 |
| 94 | BRAF | 0.47541107 |
| 95 | SYK | 0.46719743 |
| 96 | MST4 | 0.45395091 |
| 97 | ITK | 0.45349268 |
| 98 | PRKCE | 0.45245387 |
| 99 | PLK3 | 0.44389430 |
| 100 | PRKACG | 0.41695900 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.16654866 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.89723769 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.17969858 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.90198667 |
| 5 | Alzheimers disease_Homo sapiens_hsa05010 | 2.87793886 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.84190905 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.67378478 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.61981356 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.33877343 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.17484494 |
| 11 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.12268231 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.05146424 |
| 13 | Sulfur relay system_Homo sapiens_hsa04122 | 1.99518931 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.96366155 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.89511932 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.83844871 |
| 17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.61928586 |
| 18 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.51594328 |
| 19 | Spliceosome_Homo sapiens_hsa03040 | 1.45920234 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.42442272 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.40525310 |
| 22 | DNA replication_Homo sapiens_hsa03030 | 1.39877151 |
| 23 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.24948995 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23779294 |
| 25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.20840007 |
| 26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.18233498 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.17875680 |
| 28 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.17073109 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.15993592 |
| 30 | Base excision repair_Homo sapiens_hsa03410 | 1.13727286 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.11966759 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09265088 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.08667721 |
| 34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.03589080 |
| 35 | Asthma_Homo sapiens_hsa05310 | 1.02535586 |
| 36 | RNA transport_Homo sapiens_hsa03013 | 1.02152689 |
| 37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.02108768 |
| 38 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.00670171 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.00265715 |
| 40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.95748202 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.90361665 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.90027898 |
| 43 | Metabolic pathways_Homo sapiens_hsa01100 | 0.85270623 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83731426 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.82223141 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.79960806 |
| 47 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.76246728 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.74506160 |
| 49 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.73904204 |
| 50 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.73233675 |
| 51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70305177 |
| 52 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70193218 |
| 53 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.69676111 |
| 54 | Nicotine addiction_Homo sapiens_hsa05033 | 0.69534845 |
| 55 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69048414 |
| 56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.68922802 |
| 57 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.64788320 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.62537374 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.60855750 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60276836 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.59832140 |
| 62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.56835197 |
| 63 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56817862 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56336140 |
| 65 | Allograft rejection_Homo sapiens_hsa05330 | 0.56263574 |
| 66 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55507061 |
| 67 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55156468 |
| 68 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55155893 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54792194 |
| 70 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.51889893 |
| 71 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.51624049 |
| 72 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51520664 |
| 73 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.51496422 |
| 74 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.51232119 |
| 75 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.49358297 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44384099 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44086209 |
| 78 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42345771 |
| 79 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.41458284 |
| 80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.39999936 |
| 81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37821726 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37169675 |
| 83 | Taste transduction_Homo sapiens_hsa04742 | 0.36500256 |
| 84 | Morphine addiction_Homo sapiens_hsa05032 | 0.36416838 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35554322 |
| 86 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.32697865 |
| 87 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.30056710 |
| 88 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29453365 |
| 89 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.28630723 |
| 90 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.28143900 |
| 91 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.27362746 |
| 92 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.24669356 |
| 93 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.23405593 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.20566712 |
| 95 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.18466024 |
| 96 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16450132 |
| 97 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.15621602 |
| 98 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.15372115 |
| 99 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.14238095 |
| 100 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.13647826 |

