

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 8.75144200 |
| 2 | negative regulation of protein localization to cell surface (GO:2000009) | 7.32581464 |
| 3 | negative regulation of cardiac muscle tissue growth (GO:0055022) | 6.81928706 |
| 4 | negative regulation of heart growth (GO:0061117) | 6.81928706 |
| 5 | regulation of sarcomere organization (GO:0060297) | 6.49059342 |
| 6 | regulation of skeletal muscle contraction (GO:0014819) | 6.19207674 |
| 7 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 6.14656071 |
| 8 | plasma membrane repair (GO:0001778) | 6.01328465 |
| 9 | negative regulation of cardiac muscle tissue development (GO:0055026) | 5.90023857 |
| 10 | negative regulation of organelle assembly (GO:1902116) | 5.66967760 |
| 11 | membrane raft organization (GO:0031579) | 5.62005502 |
| 12 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 5.36561435 |
| 13 | negative regulation of muscle hypertrophy (GO:0014741) | 5.32530251 |
| 14 | ribonucleoprotein complex disassembly (GO:0032988) | 5.29390317 |
| 15 | positive regulation of respiratory burst (GO:0060267) | 5.27433414 |
| 16 | negative regulation of monooxygenase activity (GO:0032769) | 5.25539064 |
| 17 | DNA deamination (GO:0045006) | 4.65457018 |
| 18 | membrane assembly (GO:0071709) | 4.50599688 |
| 19 | regulation of cardiac muscle cell differentiation (GO:2000725) | 4.47027575 |
| 20 | regulation of action potential (GO:0098900) | 4.32040036 |
| 21 | organelle disassembly (GO:1903008) | 4.28571478 |
| 22 | lens fiber cell differentiation (GO:0070306) | 4.27407174 |
| 23 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.23946159 |
| 24 | regulation of respiratory burst (GO:0060263) | 4.22175938 |
| 25 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 4.03912623 |
| 26 | positive regulation of glomerulus development (GO:0090193) | 4.00409129 |
| 27 | regulation of glomerulus development (GO:0090192) | 3.96618649 |
| 28 | response to pheromone (GO:0019236) | 3.76917602 |
| 29 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.73122789 |
| 30 | response to lipoprotein particle (GO:0055094) | 3.72510130 |
| 31 | somite development (GO:0061053) | 3.70003476 |
| 32 | striated muscle atrophy (GO:0014891) | 3.66725445 |
| 33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.64763001 |
| 34 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.62458834 |
| 35 | cellular response to ATP (GO:0071318) | 3.55558956 |
| 36 | protein heterotetramerization (GO:0051290) | 3.50618691 |
| 37 | pericardium development (GO:0060039) | 3.50473481 |
| 38 | regulation of alkaline phosphatase activity (GO:0010692) | 3.50444525 |
| 39 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 3.50171687 |
| 40 | synapsis (GO:0007129) | 3.49362861 |
| 41 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.42807376 |
| 42 | negative regulation of organ growth (GO:0046621) | 3.39518462 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.39254623 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.39254623 |
| 45 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.39254623 |
| 46 | muscle atrophy (GO:0014889) | 3.33433005 |
| 47 | regulation of membrane repolarization (GO:0060306) | 3.30402177 |
| 48 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.17210809 |
| 49 | muscle cell cellular homeostasis (GO:0046716) | 3.15020097 |
| 50 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.14644409 |
| 51 | protein K6-linked ubiquitination (GO:0085020) | 3.14541188 |
| 52 | negative regulation of cell size (GO:0045792) | 3.09077899 |
| 53 | negative regulation of oxidoreductase activity (GO:0051354) | 3.08692788 |
| 54 | lateral sprouting from an epithelium (GO:0060601) | 3.05927545 |
| 55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.05016877 |
| 56 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.05016877 |
| 57 | protein complex biogenesis (GO:0070271) | 3.02988264 |
| 58 | cytoplasmic microtubule organization (GO:0031122) | 3.02472256 |
| 59 | negative regulation of acute inflammatory response (GO:0002674) | 3.01581462 |
| 60 | organ formation (GO:0048645) | 3.00156141 |
| 61 | lymphangiogenesis (GO:0001946) | 2.98548708 |
| 62 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.88947768 |
| 63 | postreplication repair (GO:0006301) | 2.88771161 |
| 64 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 2.87845423 |
| 65 | muscle cell fate commitment (GO:0042693) | 2.85182668 |
| 66 | negative regulation of muscle tissue development (GO:1901862) | 2.84476377 |
| 67 | positive regulation of protein autophosphorylation (GO:0031954) | 2.84016923 |
| 68 | positive regulation of fatty acid oxidation (GO:0046321) | 2.83548764 |
| 69 | regulation of cell proliferation involved in kidney development (GO:1901722) | 2.81347872 |
| 70 | response to gravity (GO:0009629) | 2.78986218 |
| 71 | negative regulation of striated muscle tissue development (GO:0045843) | 2.78970752 |
| 72 | positive regulation of myotube differentiation (GO:0010831) | 2.78816432 |
| 73 | negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) | 2.77803397 |
| 74 | regulation of receptor binding (GO:1900120) | 2.75419275 |
| 75 | negative regulation of muscle organ development (GO:0048635) | 2.74126468 |
| 76 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 2.69423531 |
| 77 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.69176466 |
| 78 | white fat cell differentiation (GO:0050872) | 2.67567195 |
| 79 | regulation of p38MAPK cascade (GO:1900744) | 2.67503078 |
| 80 | thyroid gland development (GO:0030878) | 2.67187174 |
| 81 | response to interferon-beta (GO:0035456) | 2.67024589 |
| 82 | positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) | 2.66338068 |
| 83 | pharyngeal system development (GO:0060037) | 2.65731955 |
| 84 | endoderm formation (GO:0001706) | 2.65125750 |
| 85 | intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) | 2.62672687 |
| 86 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.61340670 |
| 87 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.60891058 |
| 88 | muscle organ morphogenesis (GO:0048644) | 2.60093497 |
| 89 | regulation of collateral sprouting (GO:0048670) | 2.59779202 |
| 90 | positive regulation of microtubule polymerization (GO:0031116) | 2.59713362 |
| 91 | negative regulation of telomere maintenance (GO:0032205) | 2.58989104 |
| 92 | response to muscle activity (GO:0014850) | 2.58056066 |
| 93 | lung morphogenesis (GO:0060425) | 2.57940613 |
| 94 | positive regulation of extracellular matrix organization (GO:1903055) | 2.56473091 |
| 95 | chromosome organization involved in meiosis (GO:0070192) | 2.55637115 |
| 96 | regulation of hippo signaling (GO:0035330) | 2.54254209 |
| 97 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.54254038 |
| 98 | regulation of potassium ion transmembrane transport (GO:1901379) | 2.53480188 |
| 99 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 2.51460825 |
| 100 | regulation of sequestering of triglyceride (GO:0010889) | 2.51045662 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 4.41955497 |
| 2 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.11586506 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.02747726 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.81568668 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.22730863 |
| 6 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.98950448 |
| 7 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.58053292 |
| 8 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.29900449 |
| 9 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.29900449 |
| 10 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.29900449 |
| 11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.93948454 |
| 12 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.87001755 |
| 13 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.86919325 |
| 14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.85437571 |
| 15 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.82490884 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.78562046 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73072968 |
| 18 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.72115313 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.71078844 |
| 20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.70178336 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67815327 |
| 22 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.67152878 |
| 23 | P300_19829295_ChIP-Seq_ESCs_Human | 1.66372103 |
| 24 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.63495286 |
| 25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.61816508 |
| 26 | CJUN_26792858_Chip-Seq_BT549_Human | 1.59808189 |
| 27 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.55687424 |
| 28 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.53494199 |
| 29 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.48604911 |
| 30 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.46060161 |
| 31 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.40430043 |
| 32 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.39965507 |
| 33 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.38717214 |
| 34 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38414577 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.37867354 |
| 36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.37611936 |
| 37 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.36597373 |
| 38 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.36052888 |
| 39 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.35818232 |
| 40 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.35189500 |
| 41 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.32650567 |
| 42 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.31375720 |
| 43 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.30329349 |
| 44 | STAT3_23295773_ChIP-Seq_U87_Human | 1.30048686 |
| 45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.28519723 |
| 46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.28111741 |
| 47 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.25644124 |
| 48 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.25394661 |
| 49 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.25348775 |
| 50 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24903320 |
| 51 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.23480860 |
| 52 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.21599135 |
| 53 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.19969099 |
| 54 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.19844686 |
| 55 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.19319213 |
| 56 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.17809380 |
| 57 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.16241108 |
| 58 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.15520433 |
| 59 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.15459248 |
| 60 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.14918025 |
| 61 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.14806774 |
| 62 | NFYB_21822215_ChIP-Seq_K562_Human | 1.14243374 |
| 63 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.13821337 |
| 64 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.12466410 |
| 65 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.12366735 |
| 66 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.10680508 |
| 67 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.10546256 |
| 68 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.09132886 |
| 69 | TCF4_23295773_ChIP-Seq_U87_Human | 1.08612231 |
| 70 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.06426357 |
| 71 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.05601765 |
| 72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.05546470 |
| 73 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.05546470 |
| 74 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.05027335 |
| 75 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.04798795 |
| 76 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.04563419 |
| 77 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04488969 |
| 78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.04111690 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.04111690 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03252834 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03252834 |
| 82 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.02937314 |
| 83 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.02702923 |
| 84 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.02214882 |
| 85 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.02190653 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01973494 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.00679873 |
| 88 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.99401631 |
| 89 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.99302067 |
| 90 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99277731 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.99020720 |
| 92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.98924437 |
| 93 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.98822368 |
| 94 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.97946158 |
| 95 | TBL1_22424771_ChIP-Seq_293T_Human | 0.96924959 |
| 96 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.96753741 |
| 97 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.96602676 |
| 98 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96250344 |
| 99 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.95537456 |
| 100 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.93963882 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003950_abnormal_plasma_membrane | 9.58354610 |
| 2 | MP0003646_muscle_fatigue | 4.83712244 |
| 3 | MP0002102_abnormal_ear_morphology | 4.00780806 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 3.93533371 |
| 5 | MP0005670_abnormal_white_adipose | 3.54991960 |
| 6 | MP0000749_muscle_degeneration | 2.83188489 |
| 7 | MP0001485_abnormal_pinna_reflex | 2.64017271 |
| 8 | MP0005646_abnormal_pituitary_gland | 2.57355418 |
| 9 | MP0009053_abnormal_anal_canal | 2.41754718 |
| 10 | MP0005360_urolithiasis | 2.25380340 |
| 11 | MP0002160_abnormal_reproductive_system | 2.17677413 |
| 12 | MP0000537_abnormal_urethra_morphology | 2.08062973 |
| 13 | MP0004885_abnormal_endolymph | 2.04008345 |
| 14 | MP0008872_abnormal_physiological_respon | 1.79197005 |
| 15 | MP0000049_abnormal_middle_ear | 1.78182173 |
| 16 | MP0009780_abnormal_chondrocyte_physiolo | 1.73732659 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.65938984 |
| 18 | MP0005174_abnormal_tail_pigmentation | 1.64814212 |
| 19 | MP0004185_abnormal_adipocyte_glucose | 1.63767775 |
| 20 | MP0000678_abnormal_parathyroid_gland | 1.60716749 |
| 21 | MP0000015_abnormal_ear_pigmentation | 1.54440493 |
| 22 | MP0003195_calcinosis | 1.53692052 |
| 23 | MP0008775_abnormal_heart_ventricle | 1.50350010 |
| 24 | MP0002282_abnormal_trachea_morphology | 1.50006987 |
| 25 | MP0003724_increased_susceptibility_to | 1.48539399 |
| 26 | MP0004142_abnormal_muscle_tone | 1.47031158 |
| 27 | MP0003136_yellow_coat_color | 1.47017321 |
| 28 | MP0004145_abnormal_muscle_electrophysio | 1.42006053 |
| 29 | MP0006292_abnormal_olfactory_placode | 1.40953008 |
| 30 | MP0005084_abnormal_gallbladder_morpholo | 1.31044483 |
| 31 | MP0001661_extended_life_span | 1.29378410 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.27061410 |
| 33 | MP0002234_abnormal_pharynx_morphology | 1.26285036 |
| 34 | MP0005389_reproductive_system_phenotype | 1.25221023 |
| 35 | MP0001853_heart_inflammation | 1.23956008 |
| 36 | MP0003938_abnormal_ear_development | 1.23389809 |
| 37 | MP0000467_abnormal_esophagus_morphology | 1.23114929 |
| 38 | MP0002163_abnormal_gland_morphology | 1.21688544 |
| 39 | MP0003937_abnormal_limbs/digits/tail_de | 1.13437234 |
| 40 | MP0001756_abnormal_urination | 1.12233933 |
| 41 | MP0008789_abnormal_olfactory_epithelium | 1.12116452 |
| 42 | MP0003786_premature_aging | 1.11882457 |
| 43 | MP0002638_abnormal_pupillary_reflex | 1.11511134 |
| 44 | MP0009250_abnormal_appendicular_skeleto | 1.11118529 |
| 45 | MP0004084_abnormal_cardiac_muscle | 1.07833306 |
| 46 | MP0009765_abnormal_xenobiotic_induced | 1.06451217 |
| 47 | MP0003252_abnormal_bile_duct | 1.04651558 |
| 48 | MP0000751_myopathy | 1.01761673 |
| 49 | MP0002249_abnormal_larynx_morphology | 0.95331249 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 0.92096646 |
| 51 | MP0002095_abnormal_skin_pigmentation | 0.92077488 |
| 52 | MP0003119_abnormal_digestive_system | 0.91908534 |
| 53 | MP0001764_abnormal_homeostasis | 0.90577943 |
| 54 | MP0005367_renal/urinary_system_phenotyp | 0.90128150 |
| 55 | MP0000516_abnormal_urinary_system | 0.90128150 |
| 56 | MP0003693_abnormal_embryo_hatching | 0.89688141 |
| 57 | MP0004130_abnormal_muscle_cell | 0.88273289 |
| 58 | MP0004272_abnormal_basement_membrane | 0.88169326 |
| 59 | MP0005023_abnormal_wound_healing | 0.85955273 |
| 60 | MP0002928_abnormal_bile_duct | 0.85388741 |
| 61 | MP0008995_early_reproductive_senescence | 0.84214658 |
| 62 | MP0003828_pulmonary_edema | 0.81665997 |
| 63 | MP0002108_abnormal_muscle_morphology | 0.80494567 |
| 64 | MP0005408_hypopigmentation | 0.79171554 |
| 65 | MP0008058_abnormal_DNA_repair | 0.78126171 |
| 66 | MP0003283_abnormal_digestive_organ | 0.77014631 |
| 67 | MP0005410_abnormal_fertilization | 0.76640255 |
| 68 | MP0010368_abnormal_lymphatic_system | 0.76209534 |
| 69 | MP0005620_abnormal_muscle_contractility | 0.75302891 |
| 70 | MP0000013_abnormal_adipose_tissue | 0.74160897 |
| 71 | MP0003045_fibrosis | 0.73329565 |
| 72 | MP0008877_abnormal_DNA_methylation | 0.71890627 |
| 73 | MP0002277_abnormal_respiratory_mucosa | 0.71473861 |
| 74 | MP0003936_abnormal_reproductive_system | 0.70772392 |
| 75 | MP0002135_abnormal_kidney_morphology | 0.67669420 |
| 76 | MP0002972_abnormal_cardiac_muscle | 0.67271909 |
| 77 | MP0002106_abnormal_muscle_physiology | 0.66991673 |
| 78 | MP0004134_abnormal_chest_morphology | 0.66926292 |
| 79 | MP0009785_altered_susceptibility_to | 0.66880693 |
| 80 | MP0003942_abnormal_urinary_system | 0.65208899 |
| 81 | MP0001542_abnormal_bone_strength | 0.64725372 |
| 82 | MP0000631_abnormal_neuroendocrine_gland | 0.63394772 |
| 83 | MP0000759_abnormal_skeletal_muscle | 0.61982822 |
| 84 | MP0002932_abnormal_joint_morphology | 0.61408646 |
| 85 | MP0005369_muscle_phenotype | 0.60953494 |
| 86 | MP0003806_abnormal_nucleotide_metabolis | 0.60760054 |
| 87 | MP0000470_abnormal_stomach_morphology | 0.60477342 |
| 88 | MP0005195_abnormal_posterior_eye | 0.60124887 |
| 89 | MP0005551_abnormal_eye_electrophysiolog | 0.59775535 |
| 90 | MP0003315_abnormal_perineum_morphology | 0.59169048 |
| 91 | MP0002938_white_spotting | 0.58755854 |
| 92 | MP0002089_abnormal_postnatal_growth/wei | 0.57155112 |
| 93 | MP0000681_abnormal_thyroid_gland | 0.56936155 |
| 94 | MP0001486_abnormal_startle_reflex | 0.56924081 |
| 95 | MP0006054_spinal_hemorrhage | 0.55927257 |
| 96 | MP0005379_endocrine/exocrine_gland_phen | 0.55809451 |
| 97 | MP0005330_cardiomyopathy | 0.53506050 |
| 98 | MP0000230_abnormal_systemic_arterial | 0.53468465 |
| 99 | MP0000750_abnormal_muscle_regeneration | 0.53216583 |
| 100 | MP0004381_abnormal_hair_follicle | 0.53044116 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Calf muscle hypertrophy (HP:0008981) | 5.64157772 |
| 2 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.88113512 |
| 3 | Short 1st metacarpal (HP:0010034) | 4.33747021 |
| 4 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 4.33747021 |
| 5 | Exercise-induced muscle cramps (HP:0003710) | 4.00958961 |
| 6 | Exercise-induced myalgia (HP:0003738) | 3.98470655 |
| 7 | Abnormality of DNA repair (HP:0003254) | 3.96460295 |
| 8 | Abnormality of the 1st metacarpal (HP:0010009) | 3.77885987 |
| 9 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.52793852 |
| 10 | Renal cortical cysts (HP:0000803) | 3.49430239 |
| 11 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.46077656 |
| 12 | Acute necrotizing encephalopathy (HP:0006965) | 3.43214826 |
| 13 | Increased corneal curvature (HP:0100692) | 3.42301402 |
| 14 | Keratoconus (HP:0000563) | 3.42301402 |
| 15 | Popliteal pterygium (HP:0009756) | 3.38783712 |
| 16 | Fused cervical vertebrae (HP:0002949) | 3.29985801 |
| 17 | Abnormality of the nasal septum (HP:0000419) | 3.28121630 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.13950360 |
| 19 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 3.11000376 |
| 20 | Abnormality of the renal cortex (HP:0011035) | 3.00435179 |
| 21 | Acute encephalopathy (HP:0006846) | 2.99409907 |
| 22 | Absent thumb (HP:0009777) | 2.96130178 |
| 23 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.88990383 |
| 24 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.88292924 |
| 25 | Subaortic stenosis (HP:0001682) | 2.88292924 |
| 26 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.86111420 |
| 27 | Myotonia (HP:0002486) | 2.85765477 |
| 28 | Abnormality of the renal collecting system (HP:0004742) | 2.84539664 |
| 29 | Stenosis of the external auditory canal (HP:0000402) | 2.84516330 |
| 30 | Absent phalangeal crease (HP:0006109) | 2.80285447 |
| 31 | Abnormality of placental membranes (HP:0011409) | 2.78157873 |
| 32 | Amniotic constriction ring (HP:0009775) | 2.78157873 |
| 33 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.76510438 |
| 34 | Asymmetric septal hypertrophy (HP:0001670) | 2.74950868 |
| 35 | Ectopic kidney (HP:0000086) | 2.73221693 |
| 36 | Short hallux (HP:0010109) | 2.71413902 |
| 37 | Type 2 muscle fiber atrophy (HP:0003554) | 2.66406616 |
| 38 | Fatigable weakness (HP:0003473) | 2.66328496 |
| 39 | Abnormality of the neuromuscular junction (HP:0003398) | 2.66328496 |
| 40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.63644048 |
| 41 | Prolonged QT interval (HP:0001657) | 2.61987056 |
| 42 | Decreased subcutaneous fat (HP:0001002) | 2.60822021 |
| 43 | Gowers sign (HP:0003391) | 2.56565740 |
| 44 | Pancreatic cysts (HP:0001737) | 2.54146440 |
| 45 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.53568424 |
| 46 | Short phalanx of the thumb (HP:0009660) | 2.46958976 |
| 47 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.44851049 |
| 48 | Severe visual impairment (HP:0001141) | 2.44256311 |
| 49 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.42454440 |
| 50 | Poor suck (HP:0002033) | 2.41840508 |
| 51 | Hypoplasia of the thymus (HP:0000778) | 2.37974689 |
| 52 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.37925754 |
| 53 | Clubbing of toes (HP:0100760) | 2.34387283 |
| 54 | Abnormality of subcutaneous fat tissue (HP:0001001) | 2.34385997 |
| 55 | Morphological abnormality of the middle ear (HP:0008609) | 2.34001307 |
| 56 | Mitochondrial inheritance (HP:0001427) | 2.31556517 |
| 57 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.29628617 |
| 58 | Abnormal finger flexion creases (HP:0006143) | 2.29605968 |
| 59 | Aplasia of the musculature (HP:0100854) | 2.28674678 |
| 60 | Chromsome breakage (HP:0040012) | 2.26550535 |
| 61 | Duplicated collecting system (HP:0000081) | 2.25764899 |
| 62 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.25574530 |
| 63 | Posterior subcapsular cataract (HP:0007787) | 2.22515942 |
| 64 | Tubular atrophy (HP:0000092) | 2.17812502 |
| 65 | Adrenal hypoplasia (HP:0000835) | 2.15453940 |
| 66 | Muscle stiffness (HP:0003552) | 2.15267607 |
| 67 | Oligomenorrhea (HP:0000876) | 2.14979377 |
| 68 | Abnormality of the ileum (HP:0001549) | 2.12025243 |
| 69 | Abnormality of the calf musculature (HP:0001430) | 2.11315303 |
| 70 | Muscle fiber atrophy (HP:0100295) | 2.10876940 |
| 71 | Sudden death (HP:0001699) | 2.10741939 |
| 72 | Irregular vertebral endplates (HP:0003301) | 2.09163262 |
| 73 | Congenital sensorineural hearing impairment (HP:0008527) | 2.07113548 |
| 74 | Neck muscle weakness (HP:0000467) | 2.05899236 |
| 75 | Meckel diverticulum (HP:0002245) | 2.05305378 |
| 76 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.03835089 |
| 77 | Hamartoma of the eye (HP:0010568) | 2.00590990 |
| 78 | Synostosis of carpal bones (HP:0005048) | 2.00071239 |
| 79 | Abnormality of midbrain morphology (HP:0002418) | 1.99393580 |
| 80 | Molar tooth sign on MRI (HP:0002419) | 1.99393580 |
| 81 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.98419947 |
| 82 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.96031659 |
| 83 | Chorioretinal atrophy (HP:0000533) | 1.95576909 |
| 84 | Congenital, generalized hypertrichosis (HP:0004540) | 1.95282711 |
| 85 | Nephronophthisis (HP:0000090) | 1.94468097 |
| 86 | Pendular nystagmus (HP:0012043) | 1.93163803 |
| 87 | Attenuation of retinal blood vessels (HP:0007843) | 1.92373306 |
| 88 | Pancreatic fibrosis (HP:0100732) | 1.90725010 |
| 89 | Cubitus valgus (HP:0002967) | 1.90359393 |
| 90 | True hermaphroditism (HP:0010459) | 1.88036895 |
| 91 | Abnormality of the costochondral junction (HP:0000919) | 1.87268773 |
| 92 | Brushfield spots (HP:0001088) | 1.86959542 |
| 93 | Abnormality of the renal medulla (HP:0100957) | 1.85539632 |
| 94 | Optic disc pallor (HP:0000543) | 1.82892380 |
| 95 | Abnormality of chromosome stability (HP:0003220) | 1.81656109 |
| 96 | Humeroradial synostosis (HP:0003041) | 1.80727388 |
| 97 | Synostosis involving the elbow (HP:0003938) | 1.80727388 |
| 98 | Increased CSF lactate (HP:0002490) | 1.80286395 |
| 99 | Abnormality of the carotid arteries (HP:0005344) | 1.80179931 |
| 100 | Thick nail (HP:0001805) | 1.79151608 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | INSRR | 6.21601038 |
| 2 | FRK | 3.99628341 |
| 3 | MAPKAPK5 | 3.83412238 |
| 4 | MUSK | 3.43696582 |
| 5 | TRIM28 | 2.77596857 |
| 6 | CDK8 | 2.69973080 |
| 7 | EIF2AK3 | 2.30296917 |
| 8 | GRK1 | 2.12624974 |
| 9 | CDK9 | 1.99676900 |
| 10 | EIF2AK1 | 1.96453006 |
| 11 | NUAK1 | 1.93770780 |
| 12 | TAOK3 | 1.93262019 |
| 13 | PINK1 | 1.92668554 |
| 14 | ADRBK2 | 1.86874518 |
| 15 | SIK3 | 1.82876273 |
| 16 | CCNB1 | 1.67267782 |
| 17 | VRK2 | 1.66909252 |
| 18 | PLK2 | 1.63213485 |
| 19 | NME1 | 1.63018046 |
| 20 | MAP3K12 | 1.58411923 |
| 21 | MELK | 1.49178061 |
| 22 | PIK3CG | 1.42620610 |
| 23 | DAPK1 | 1.28261346 |
| 24 | BMPR1B | 1.27333670 |
| 25 | PIK3CA | 1.18918728 |
| 26 | MAP4K2 | 1.15201248 |
| 27 | MAP3K7 | 1.10089785 |
| 28 | DMPK | 1.07477386 |
| 29 | ERBB3 | 1.06409709 |
| 30 | PAK6 | 1.05989967 |
| 31 | CDC7 | 1.02422983 |
| 32 | MYLK | 1.01676492 |
| 33 | MAP2K1 | 0.99364711 |
| 34 | FER | 0.98693787 |
| 35 | PAK3 | 0.98063927 |
| 36 | TAF1 | 0.95667517 |
| 37 | STK16 | 0.94402436 |
| 38 | GRK5 | 0.93498944 |
| 39 | LMTK2 | 0.90944775 |
| 40 | BCR | 0.90813978 |
| 41 | STK39 | 0.89746508 |
| 42 | TNIK | 0.89544597 |
| 43 | TEC | 0.81637905 |
| 44 | BRSK2 | 0.80674065 |
| 45 | WEE1 | 0.79713586 |
| 46 | PRKCE | 0.75921195 |
| 47 | FLT3 | 0.72962068 |
| 48 | STK38L | 0.72442468 |
| 49 | MAP3K9 | 0.70272052 |
| 50 | VRK1 | 0.67274283 |
| 51 | MST1R | 0.66373705 |
| 52 | PLK3 | 0.65676106 |
| 53 | MST4 | 0.64575724 |
| 54 | WNK3 | 0.63700549 |
| 55 | PRKCI | 0.57265520 |
| 56 | MKNK2 | 0.56699665 |
| 57 | ACVR1B | 0.56049189 |
| 58 | OXSR1 | 0.54652406 |
| 59 | PLK4 | 0.53895497 |
| 60 | MAPKAPK3 | 0.52538551 |
| 61 | CSNK1A1 | 0.51891293 |
| 62 | EIF2AK2 | 0.51821111 |
| 63 | IKBKB | 0.51787529 |
| 64 | BCKDK | 0.51695912 |
| 65 | DAPK3 | 0.51350353 |
| 66 | MINK1 | 0.50395206 |
| 67 | MAP3K3 | 0.50377031 |
| 68 | PRKAA1 | 0.49843311 |
| 69 | AURKA | 0.49254691 |
| 70 | IGF1R | 0.49149078 |
| 71 | ABL1 | 0.49113468 |
| 72 | ADRBK1 | 0.48162522 |
| 73 | CSNK1D | 0.45500041 |
| 74 | ERBB4 | 0.44725279 |
| 75 | CLK1 | 0.43077927 |
| 76 | DAPK2 | 0.42804362 |
| 77 | PRKCG | 0.42452563 |
| 78 | PRKCQ | 0.42343390 |
| 79 | ABL2 | 0.42108344 |
| 80 | CHEK2 | 0.41458826 |
| 81 | CSNK1G2 | 0.40208392 |
| 82 | DDR2 | 0.39910061 |
| 83 | STK10 | 0.39065330 |
| 84 | AKT3 | 0.37453159 |
| 85 | EPHB2 | 0.37427772 |
| 86 | CAMK2A | 0.37076304 |
| 87 | PRKD2 | 0.35601821 |
| 88 | RIPK4 | 0.35550126 |
| 89 | MOS | 0.35500528 |
| 90 | CAMK2D | 0.35380065 |
| 91 | CSNK1G1 | 0.34573469 |
| 92 | CSNK2A1 | 0.34555395 |
| 93 | PRKCA | 0.33067302 |
| 94 | ROCK1 | 0.31430580 |
| 95 | NTRK3 | 0.30606758 |
| 96 | ATR | 0.30325833 |
| 97 | EGFR | 0.28945096 |
| 98 | TNK2 | 0.28918738 |
| 99 | LIMK1 | 0.28815112 |
| 100 | PLK1 | 0.27377180 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Homologous recombination_Homo sapiens_hsa03440 | 3.09531460 |
| 2 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.83619996 |
| 3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.79265227 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.75917738 |
| 5 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.57754247 |
| 6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.57286023 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.39717097 |
| 8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.31692162 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.26512627 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.20953666 |
| 11 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.17303084 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.10481771 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.01956711 |
| 14 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.93383313 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.92506153 |
| 16 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.85018685 |
| 17 | Histidine metabolism_Homo sapiens_hsa00340 | 1.84251475 |
| 18 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.72100919 |
| 19 | Basal transcription factors_Homo sapiens_hsa03022 | 1.69991206 |
| 20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.67452881 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.58660841 |
| 22 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.57516035 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.47625423 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.44351396 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.40246559 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.39289107 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.37276704 |
| 28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.34635188 |
| 29 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.33120091 |
| 30 | Protein export_Homo sapiens_hsa03060 | 1.32916198 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27593232 |
| 32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.27287904 |
| 33 | Retinol metabolism_Homo sapiens_hsa00830 | 1.27015922 |
| 34 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.23220398 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.20517035 |
| 36 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.19976745 |
| 37 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.18781674 |
| 38 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.18725033 |
| 39 | RNA degradation_Homo sapiens_hsa03018 | 1.16726180 |
| 40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.16024958 |
| 41 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.11354474 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.05994073 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.04107265 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.03342102 |
| 45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.03147575 |
| 46 | Huntingtons disease_Homo sapiens_hsa05016 | 0.93363874 |
| 47 | ABC transporters_Homo sapiens_hsa02010 | 0.92442508 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.87519079 |
| 49 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.87494256 |
| 50 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.85565981 |
| 51 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.85208126 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.84520539 |
| 53 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.81741945 |
| 54 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.81130454 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81129654 |
| 56 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.80363564 |
| 57 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.80305960 |
| 58 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.77936186 |
| 59 | Lysine degradation_Homo sapiens_hsa00310 | 0.77916579 |
| 60 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.76866613 |
| 61 | Taste transduction_Homo sapiens_hsa04742 | 0.75313468 |
| 62 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.75000713 |
| 63 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.73052827 |
| 64 | Mismatch repair_Homo sapiens_hsa03430 | 0.70742179 |
| 65 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65488499 |
| 66 | Peroxisome_Homo sapiens_hsa04146 | 0.64104861 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.62280206 |
| 68 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.58432812 |
| 69 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.56701114 |
| 70 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.56366384 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55877829 |
| 72 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.55639873 |
| 73 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.55166305 |
| 74 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.54908010 |
| 75 | DNA replication_Homo sapiens_hsa03030 | 0.52895158 |
| 76 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.52492403 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52474143 |
| 78 | Melanoma_Homo sapiens_hsa05218 | 0.45973562 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44350163 |
| 80 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.44115612 |
| 81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.42227597 |
| 82 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.41765100 |
| 83 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40878422 |
| 84 | RNA transport_Homo sapiens_hsa03013 | 0.39865459 |
| 85 | Purine metabolism_Homo sapiens_hsa00230 | 0.39043438 |
| 86 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.39003793 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38713872 |
| 88 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.38473776 |
| 89 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.37460839 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.36544347 |
| 91 | Insulin secretion_Homo sapiens_hsa04911 | 0.35922739 |
| 92 | Base excision repair_Homo sapiens_hsa03410 | 0.34028384 |
| 93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.33756013 |
| 94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.33326187 |
| 95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30545714 |
| 96 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.30523532 |
| 97 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.30226230 |
| 98 | Morphine addiction_Homo sapiens_hsa05032 | 0.30123900 |
| 99 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29375783 |
| 100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.27360927 |

