RPS15A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* translational termination (GO:0006415)9.68649066
2ribosomal small subunit assembly (GO:0000028)9.08833785
3ribosomal small subunit biogenesis (GO:0042274)8.99458525
4* translational elongation (GO:0006414)8.15468233
5* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)8.09723701
6* cotranslational protein targeting to membrane (GO:0006613)7.95549155
7* protein targeting to ER (GO:0045047)7.93765308
8maturation of SSU-rRNA (GO:0030490)7.71456980
9* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)7.62989975
10* establishment of protein localization to endoplasmic reticulum (GO:0072599)7.60295338
11* cellular protein complex disassembly (GO:0043624)7.46389099
12* viral life cycle (GO:0019058)7.45007704
13* protein localization to endoplasmic reticulum (GO:0070972)7.38955768
14* translational initiation (GO:0006413)7.07699052
15* protein complex disassembly (GO:0043241)6.55280276
16ribosomal large subunit biogenesis (GO:0042273)6.44454536
17* macromolecular complex disassembly (GO:0032984)6.08950517
18* nuclear-transcribed mRNA catabolic process (GO:0000956)5.47631972
19* protein targeting to membrane (GO:0006612)5.29637587
20* mRNA catabolic process (GO:0006402)5.19954213
21* RNA catabolic process (GO:0006401)4.82986214
22* translation (GO:0006412)4.72975169
23ribonucleoprotein complex biogenesis (GO:0022613)4.71593231
24formation of translation preinitiation complex (GO:0001731)4.09779719
25rRNA processing (GO:0006364)3.72638324
26rRNA metabolic process (GO:0016072)3.59114945
27DNA unwinding involved in DNA replication (GO:0006268)3.53547464
28* establishment of protein localization to membrane (GO:0090150)3.51429580
29negative regulation of RNA splicing (GO:0033119)3.38862409
30DNA strand elongation involved in DNA replication (GO:0006271)3.37237841
31cellular component biogenesis (GO:0044085)3.36805258
32establishment of protein localization to mitochondrial membrane (GO:0090151)3.31445872
33telomere maintenance via semi-conservative replication (GO:0032201)3.27604026
34* establishment of protein localization to organelle (GO:0072594)3.19886654
35DNA strand elongation (GO:0022616)3.18846107
36regulation of translational fidelity (GO:0006450)3.16916171
37* protein targeting (GO:0006605)3.14951376
38DNA deamination (GO:0045006)3.01142262
39mitotic chromosome condensation (GO:0007076)3.00711636
40respiratory electron transport chain (GO:0022904)2.98729877
41heterochromatin organization (GO:0070828)2.96870131
42spliceosomal complex assembly (GO:0000245)2.96213892
43chaperone-mediated protein transport (GO:0072321)2.96072861
44protein localization to kinetochore (GO:0034501)2.94251147
45establishment of integrated proviral latency (GO:0075713)2.92737167
46electron transport chain (GO:0022900)2.90247202
47spliceosomal snRNP assembly (GO:0000387)2.88503217
48telomere maintenance via recombination (GO:0000722)2.85393113
49DNA replication initiation (GO:0006270)2.84083073
50mitotic recombination (GO:0006312)2.78334534
51oxidative phosphorylation (GO:0006119)2.77409448
52ncRNA 3-end processing (GO:0043628)2.75459748
53histone mRNA metabolic process (GO:0008334)2.75228501
54myeloid cell homeostasis (GO:0002262)2.70595162
55regulation of protein heterodimerization activity (GO:0043497)2.70287034
56* cellular component disassembly (GO:0022411)2.68746733
57CENP-A containing nucleosome assembly (GO:0034080)2.67234035
58* protein localization to membrane (GO:0072657)2.67087535
59protein localization to chromosome, centromeric region (GO:0071459)2.64009479
60regulation of mitochondrial translation (GO:0070129)2.62447137
61termination of RNA polymerase II transcription (GO:0006369)2.62415939
62chromatin remodeling at centromere (GO:0031055)2.61821038
63kinetochore organization (GO:0051383)2.61252561
64nucleotide-excision repair, DNA gap filling (GO:0006297)2.60225855
65telomere maintenance via telomere lengthening (GO:0010833)2.60121877
66negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.60059205
67mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.58882425
68exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.58715675
69* gene expression (GO:0010467)2.58512253
70DNA replication checkpoint (GO:0000076)2.56493410
71pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.55898277
72mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.53436393
73mRNA splicing, via spliceosome (GO:0000398)2.53016670
74RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.53016670
75DNA replication-independent nucleosome organization (GO:0034724)2.53013533
76DNA replication-independent nucleosome assembly (GO:0006336)2.53013533
77RNA splicing, via transesterification reactions (GO:0000375)2.51231287
78ribonucleoprotein complex assembly (GO:0022618)2.50900218
79nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.48234635
80ncRNA processing (GO:0034470)2.48085638
81termination of RNA polymerase III transcription (GO:0006386)2.47430931
82transcription elongation from RNA polymerase III promoter (GO:0006385)2.47430931
83folic acid-containing compound biosynthetic process (GO:0009396)2.46768522
84pseudouridine synthesis (GO:0001522)2.46724720
85nuclear pore complex assembly (GO:0051292)2.46356840
86DNA replication-dependent nucleosome organization (GO:0034723)2.46086265
87DNA replication-dependent nucleosome assembly (GO:0006335)2.46086265
88ribosome biogenesis (GO:0042254)2.44627153
89negative regulation of DNA repair (GO:0045738)2.40430481
90* protein localization to organelle (GO:0033365)2.40251166
91energy coupled proton transport, down electrochemical gradient (GO:0015985)2.38435296
92ATP synthesis coupled proton transport (GO:0015986)2.38435296
93aerobic respiration (GO:0009060)2.37799865
94DNA-templated transcription, termination (GO:0006353)2.37606148
95mitotic nuclear envelope disassembly (GO:0007077)2.36457683
96negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.36036564
97positive regulation of viral transcription (GO:0050434)2.35292439
98ribonucleoprotein complex subunit organization (GO:0071826)2.34869288
99ribosome assembly (GO:0042255)2.34606787
100termination of RNA polymerase I transcription (GO:0006363)2.34534357
101negative regulation of mRNA processing (GO:0050686)2.32841188
102chromatin assembly or disassembly (GO:0006333)2.32652663
103establishment of viral latency (GO:0019043)2.32435835
104transcription elongation from RNA polymerase I promoter (GO:0006362)2.31361444
105transcription-coupled nucleotide-excision repair (GO:0006283)2.31166088
106chromatin assembly (GO:0031497)2.31073797
107pyrimidine nucleotide catabolic process (GO:0006244)2.29500315
108UTP biosynthetic process (GO:0006228)2.29097432
109kinetochore assembly (GO:0051382)2.28265438
110positive regulation by host of viral transcription (GO:0043923)2.26842025
111ncRNA metabolic process (GO:0034660)2.26088638
112protein neddylation (GO:0045116)2.26082433
113mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.25788801
114mitochondrial respiratory chain complex I assembly (GO:0032981)2.25788801
115NADH dehydrogenase complex assembly (GO:0010257)2.25788801
116ATP biosynthetic process (GO:0006754)2.25398439
117inner mitochondrial membrane organization (GO:0007007)2.24863895
118DNA topological change (GO:0006265)2.23770782
119protein targeting to mitochondrion (GO:0006626)2.22189990
120mitochondrial respiratory chain complex assembly (GO:0033108)2.21856868
121negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.21584431
122regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.20843524
123purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.20797853
124mitotic metaphase plate congression (GO:0007080)2.20621833
125nucleobase-containing small molecule interconversion (GO:0015949)2.20597351
126DNA duplex unwinding (GO:0032508)2.19869003
127negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.18632737
128negative regulation of ligase activity (GO:0051352)2.18632737
129anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.18542990
130DNA geometric change (GO:0032392)2.17263224
131viral mRNA export from host cell nucleus (GO:0046784)2.16930899
132regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.16908475
133* viral transcription (GO:0019083)10.1000562

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.01591570
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.72961602
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.98020006
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.87542697
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.61231593
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.40898989
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.29929738
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.20509419
9GABP_17652178_ChIP-ChIP_JURKAT_Human3.12862530
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.86171901
11* ETS1_20019798_ChIP-Seq_JURKAT_Human2.77202163
12* XRN2_22483619_ChIP-Seq_HELA_Human2.74347337
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72443548
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.70860093
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.60905201
16TP63_17297297_ChIP-ChIP_HaCaT_Human2.56767089
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.51626174
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.47821220
19ELF1_17652178_ChIP-ChIP_JURKAT_Human2.46629041
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.38497235
21VDR_23849224_ChIP-Seq_CD4+_Human2.32140958
22* TTF2_22483619_ChIP-Seq_HELA_Human2.30126418
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.17467875
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14153431
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.13326584
26ELK1_19687146_ChIP-ChIP_HELA_Human2.11365955
27TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.07071843
28* FOXP3_21729870_ChIP-Seq_TREG_Human2.02565148
29DCP1A_22483619_ChIP-Seq_HELA_Human1.98932084
30MYC_22102868_ChIP-Seq_BL_Human1.95292288
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86448610
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80214050
33* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78738407
34* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.72728330
35TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.70009609
36CIITA_25753668_ChIP-Seq_RAJI_Human1.69671907
37EGR1_19374776_ChIP-ChIP_THP-1_Human1.69536608
38E2F1_21310950_ChIP-Seq_MCF-7_Human1.59941297
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.59743268
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57163443
41FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.56700283
42* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56264829
43VDR_21846776_ChIP-Seq_THP-1_Human1.52253300
44* GABP_19822575_ChIP-Seq_HepG2_Human1.51641780
45AR_21909140_ChIP-Seq_LNCAP_Human1.50985451
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.45103923
47TP63_19390658_ChIP-ChIP_HaCaT_Human1.45042789
48FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.44184345
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.43743858
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.43045120
51ESR1_15608294_ChIP-ChIP_MCF-7_Human1.41728998
52POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39444555
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.39081479
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.38873686
55MYCN_18555785_ChIP-Seq_MESCs_Mouse1.38444840
56NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.37359854
57* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35521922
58* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.35170812
59FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.34684980
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.33443351
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.29580972
62HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29099639
63SPI1_23547873_ChIP-Seq_NB4_Human1.27695361
64ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27573653
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.26838939
66THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25423975
67MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.23384377
68* MYC_18940864_ChIP-ChIP_HL60_Human1.20351127
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.19775662
70KDM5A_27292631_Chip-Seq_BREAST_Human1.18848571
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.17746101
72BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.17329759
73CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.10198583
74YY1_21170310_ChIP-Seq_MESCs_Mouse1.10192123
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09409693
76CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.08355057
77TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08264921
78* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.08150522
79SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.07371766
80CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06763906
81UTX_26944678_Chip-Seq_JUKART_Human1.06437500
82E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.06173641
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05430599
84STAT4_19710469_ChIP-ChIP_TH1__Mouse1.04991461
85SOX2_16153702_ChIP-ChIP_HESCs_Human1.03741120
86MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.03722215
87SCL_19346495_ChIP-Seq_HPC-7_Human1.03047771
88MAF_26560356_Chip-Seq_TH1_Human1.02204302
89DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.01136786
90CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.00574294
91SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.99723843
92TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.99062043
93SOX2_18555785_ChIP-Seq_MESCs_Mouse0.98415618
94* MYB_26560356_Chip-Seq_TH2_Human0.97769492
95GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97472935
96* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.96796018
97KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.96042397
98* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.95783508
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.95533633
100SRF_21415370_ChIP-Seq_HL-1_Mouse0.95466705
101OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95211667
102RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94465202
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94293708
104SOX2_18692474_ChIP-Seq_MEFs_Mouse0.93223820
105MAF_26560356_Chip-Seq_TH2_Human0.92613792
106* MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.92309117
107CTCF_18555785_ChIP-Seq_MESCs_Mouse0.91901687
108STAT6_21828071_ChIP-Seq_BEAS2B_Human0.91504377
109STAT3_1855785_ChIP-Seq_MESCs_Mouse0.91498955
110FOXP1_21924763_ChIP-Seq_HESCs_Human0.90838333
111NANOG_21062744_ChIP-ChIP_HESCs_Human0.89390095
112CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.88978502
113POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.88398209
114* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87806548
115CHD1_26751641_Chip-Seq_LNCaP_Human0.87344291
116HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.85017604
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.83946222
118ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.78720917
119CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.78109395
120NANOG_16153702_ChIP-ChIP_HESCs_Human0.78015725

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.02594183
2MP0003693_abnormal_embryo_hatching3.70579925
3MP0006292_abnormal_olfactory_placode3.66760896
4MP0004957_abnormal_blastocyst_morpholog3.26202485
5MP0010094_abnormal_chromosome_stability2.98194084
6MP0003077_abnormal_cell_cycle2.80077522
7MP0002396_abnormal_hematopoietic_system2.66139429
8MP0003111_abnormal_nucleus_morphology2.60692418
9MP0008057_abnormal_DNA_replication2.50843824
10MP0000566_synostosis2.41798404
11MP0003763_abnormal_thymus_physiology2.35747910
12MP0000490_abnormal_crypts_of2.00976773
13MP0005174_abnormal_tail_pigmentation1.96650282
14MP0008007_abnormal_cellular_replicative1.92446823
15MP0010352_gastrointestinal_tract_polyps1.80056987
16MP0008932_abnormal_embryonic_tissue1.79667470
17MP0008058_abnormal_DNA_repair1.78394212
18MP0003890_abnormal_embryonic-extraembry1.75576993
19MP0004808_abnormal_hematopoietic_stem1.74696888
20MP0004381_abnormal_hair_follicle1.70663159
21MP0009333_abnormal_splenocyte_physiolog1.69961714
22MP0002166_altered_tumor_susceptibility1.69105469
23MP0001286_abnormal_eye_development1.65720006
24MP0002398_abnormal_bone_marrow1.59097638
25MP0006054_spinal_hemorrhage1.57172481
26MP0000703_abnormal_thymus_morphology1.57161686
27MP0008789_abnormal_olfactory_epithelium1.55608012
28MP0003122_maternal_imprinting1.55422754
29MP0002163_abnormal_gland_morphology1.54220580
30MP0000350_abnormal_cell_proliferation1.54090671
31MP0003123_paternal_imprinting1.53056713
32MP0000537_abnormal_urethra_morphology1.52721518
33MP0000685_abnormal_immune_system1.52186037
34MP0003786_premature_aging1.48490132
35MP0001800_abnormal_humoral_immune1.46119952
36MP0005671_abnormal_response_to1.44607233
37MP0002006_tumorigenesis1.42303894
38MP0001835_abnormal_antigen_presentation1.42175830
39MP0002722_abnormal_immune_system1.42046830
40MP0002697_abnormal_eye_size1.37615046
41MP0001346_abnormal_lacrimal_gland1.37582392
42MP0003567_abnormal_fetal_cardiomyocyte1.35926579
43MP0002653_abnormal_ependyma_morphology1.35675918
44MP0002938_white_spotting1.35176140
45MP0001730_embryonic_growth_arrest1.33596872
46MP0002095_abnormal_skin_pigmentation1.33436318
47MP0005394_taste/olfaction_phenotype1.33383941
48MP0005499_abnormal_olfactory_system1.33383941
49MP0002019_abnormal_tumor_incidence1.31325020
50MP0003121_genomic_imprinting1.28311885
51MP0005408_hypopigmentation1.28163532
52MP0002132_abnormal_respiratory_system1.28052360
53MP0000689_abnormal_spleen_morphology1.26930674
54MP0002420_abnormal_adaptive_immunity1.26009496
55MP0000465_gastrointestinal_hemorrhage1.23936542
56MP0001545_abnormal_hematopoietic_system1.23794465
57MP0005397_hematopoietic_system_phenotyp1.23794465
58MP0002009_preneoplasia1.23593674
59MP0001819_abnormal_immune_cell1.22944296
60MP0002102_abnormal_ear_morphology1.22594553
61MP0000716_abnormal_immune_system1.22074337
62MP0002452_abnormal_antigen_presenting1.20166035
63MP0002429_abnormal_blood_cell1.19408745
64MP0004185_abnormal_adipocyte_glucose1.17961837
65MP0001853_heart_inflammation1.17875901
66MP0005075_abnormal_melanosome_morpholog1.16558960
67MP0005501_abnormal_skin_physiology1.16433328
68MP0002796_impaired_skin_barrier1.15874580
69MP0002092_abnormal_eye_morphology1.15222313
70MP0003941_abnormal_skin_development1.14037116
71MP0003315_abnormal_perineum_morphology1.13665348
72MP0003942_abnormal_urinary_system1.13373724
73MP0002405_respiratory_system_inflammati1.12932005
74MP0000383_abnormal_hair_follicle1.12183263
75MP0009053_abnormal_anal_canal1.11474168
76MP0000372_irregular_coat_pigmentation1.11027313
77MP0002723_abnormal_immune_serum1.10603859
78MP0000049_abnormal_middle_ear1.10409112
79MP0000313_abnormal_cell_death1.09668695
80MP0000858_altered_metastatic_potential1.09443450
81MP0002160_abnormal_reproductive_system1.08865464
82MP0003937_abnormal_limbs/digits/tail_de1.08560426
83MP0010155_abnormal_intestine_physiology1.08434599
84MP0002210_abnormal_sex_determination1.08224950
85MP0001873_stomach_inflammation1.07899206
86MP0001697_abnormal_embryo_size1.06842729
87MP0002080_prenatal_lethality1.04881032
88MP0005000_abnormal_immune_tolerance1.04577380
89MP0003718_maternal_effect0.98970351
90MP0005025_abnormal_response_to0.97954077
91MP0003787_abnormal_imprinting0.97866654
92MP0002638_abnormal_pupillary_reflex0.97712594
93MP0009278_abnormal_bone_marrow0.97176886
94MP0001672_abnormal_embryogenesis/_devel0.97056146
95MP0005380_embryogenesis_phenotype0.97056146
96MP0002249_abnormal_larynx_morphology0.96467978
97MP0001216_abnormal_epidermal_layer0.96273451
98MP0002111_abnormal_tail_morphology0.96008154
99MP0002085_abnormal_embryonic_tissue0.95968785
100MP0002084_abnormal_developmental_patter0.94848414
101MP0003186_abnormal_redox_activity0.94231866
102MP0003136_yellow_coat_color0.94125933
103MP0000631_abnormal_neuroendocrine_gland0.94099525
104MP0002233_abnormal_nose_morphology0.92664729
105MP0002086_abnormal_extraembryonic_tissu0.92377897
106MP0003861_abnormal_nervous_system0.90909930
107MP0010030_abnormal_orbit_morphology0.90664350
108MP0003755_abnormal_palate_morphology0.87461090
109MP0001145_abnormal_male_reproductive0.87018029
110MP0009785_altered_susceptibility_to0.86931885
111MP0001293_anophthalmia0.86400338
112MP0002088_abnormal_embryonic_growth/wei0.86186755
113MP0003984_embryonic_growth_retardation0.86039181
114MP0010307_abnormal_tumor_latency0.85443961
115MP0002098_abnormal_vibrissa_morphology0.84866275
116MP0003436_decreased_susceptibility_to0.82971034
117MP0004197_abnormal_fetal_growth/weight/0.82792536
118MP0002148_abnormal_hypersensitivity_rea0.81010615
119MP0005387_immune_system_phenotype0.80876745
120MP0001790_abnormal_immune_system0.80876745
121MP0002282_abnormal_trachea_morphology0.80120263
122MP0000377_abnormal_hair_follicle0.79768780
123MP0001340_abnormal_eyelid_morphology0.79580688
124MP0005076_abnormal_cell_differentiation0.78750562
125MP0003866_abnormal_defecation0.78640384
126MP0004947_skin_inflammation0.78634424
127MP0010234_abnormal_vibrissa_follicle0.78386456
128MP0008995_early_reproductive_senescence0.77701937
129MP0009672_abnormal_birth_weight0.76862000
130MP0003806_abnormal_nucleotide_metabolis0.76639609
131MP0000477_abnormal_intestine_morphology0.76525817
132MP0002116_abnormal_craniofacial_bone0.75568968
133MP0002060_abnormal_skin_morphology0.74967955
134MP0003938_abnormal_ear_development0.74479812
135MP0005023_abnormal_wound_healing0.74322736
136MP0003453_abnormal_keratinocyte_physiol0.74192754
137MP0010678_abnormal_skin_adnexa0.73572718
138MP0002932_abnormal_joint_morphology0.73474459
139MP0003300_gastrointestinal_ulcer0.73111569
140MP0001348_abnormal_lacrimal_gland0.71647433
141MP0000653_abnormal_sex_gland0.71402532
142MP0006035_abnormal_mitochondrial_morpho0.70571753
143MP0000428_abnormal_craniofacial_morphol0.68346064
144MP0001929_abnormal_gametogenesis0.67879940
145MP0003385_abnormal_body_wall0.66973311
146MP0005389_reproductive_system_phenotype0.65752756
147MP0001119_abnormal_female_reproductive0.63833738
148MP0005391_vision/eye_phenotype0.62509658
149MP0001919_abnormal_reproductive_system0.61789038
150MP0008877_abnormal_DNA_methylation0.61467981
151MP0002277_abnormal_respiratory_mucosa0.61346971
152MP0004142_abnormal_muscle_tone0.61085066
153MP0004264_abnormal_extraembryonic_tissu0.60448588
154MP0003936_abnormal_reproductive_system0.59742103

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)9.34338665
2Reticulocytopenia (HP:0001896)8.55335241
3Abnormal number of erythroid precursors (HP:0012131)8.25660962
4Macrocytic anemia (HP:0001972)6.27345975
5Pallor (HP:0000980)6.04168267
6Colon cancer (HP:0003003)3.90791478
7Abnormal hemoglobin (HP:0011902)3.67220537
8Thrombocytosis (HP:0001894)3.28046132
9IgM deficiency (HP:0002850)3.26908767
10Aplastic anemia (HP:0001915)3.19052181
1111 pairs of ribs (HP:0000878)3.12627894
12Acute necrotizing encephalopathy (HP:0006965)3.12489532
13Congenital, generalized hypertrichosis (HP:0004540)3.08786979
14Aplasia/Hypoplasia of the sacrum (HP:0008517)2.99528841
15Abnormal mitochondria in muscle tissue (HP:0008316)2.94217251
16Selective tooth agenesis (HP:0001592)2.89114294
17Depressed nasal ridge (HP:0000457)2.81314290
18Abnormality of reticulocytes (HP:0004312)2.80723487
19Acute encephalopathy (HP:0006846)2.76247784
20Absent thumb (HP:0009777)2.74945987
21Stenosis of the external auditory canal (HP:0000402)2.74694699
22Mitochondrial inheritance (HP:0001427)2.73274556
23Oral leukoplakia (HP:0002745)2.69952234
24Chromosomal breakage induced by crosslinking agents (HP:0003221)2.62968846
25Septo-optic dysplasia (HP:0100842)2.60192171
26Migraine (HP:0002076)2.47502288
27Thick lower lip vermilion (HP:0000179)2.46992713
28Increased intramyocellular lipid droplets (HP:0012240)2.44780462
29Abnormal number of incisors (HP:0011064)2.44070707
30Trismus (HP:0000211)2.41783471
31Rib fusion (HP:0000902)2.38804939
32Diastasis recti (HP:0001540)2.37893211
33Multiple enchondromatosis (HP:0005701)2.36539562
34Increased CSF lactate (HP:0002490)2.36336100
35Chronic otitis media (HP:0000389)2.31881304
36Progressive macrocephaly (HP:0004481)2.30113406
37Woolly hair (HP:0002224)2.29175005
38Hepatocellular necrosis (HP:0001404)2.26687334
39Increased hepatocellular lipid droplets (HP:0006565)2.25151133
40Microvesicular hepatic steatosis (HP:0001414)2.23536381
41Abnormality of the parietal bone (HP:0002696)2.22521458
42Asplenia (HP:0001746)2.20349892
43Basal cell carcinoma (HP:0002671)2.18819392
44Abnormality of cochlea (HP:0000375)2.17424954
45Renal Fanconi syndrome (HP:0001994)2.16166548
46Exertional dyspnea (HP:0002875)2.15517919
47Cerebral edema (HP:0002181)2.14928259
48Glossoptosis (HP:0000162)2.13027906
49Recurrent bronchitis (HP:0002837)2.11970936
50Triphalangeal thumb (HP:0001199)2.10176712
51Birth length less than 3rd percentile (HP:0003561)2.07115116
52Myelodysplasia (HP:0002863)2.06756970
53Atresia of the external auditory canal (HP:0000413)2.05568991
54Abnormality of the axillary hair (HP:0100134)2.04492010
55Abnormality of secondary sexual hair (HP:0009888)2.04492010
56Aplasia/Hypoplasia of the spleen (HP:0010451)2.04373802
57Hepatic necrosis (HP:0002605)2.03637237
58Abnormality of DNA repair (HP:0003254)2.02520058
59Squamous cell carcinoma (HP:0002860)2.01762316
60Lymphoma (HP:0002665)2.01494593
61Duplication of thumb phalanx (HP:0009942)2.00872222
62IgG deficiency (HP:0004315)2.00169271
63Increased muscle lipid content (HP:0009058)1.98579205
64Hypoplasia of the radius (HP:0002984)1.98358010
65Meckel diverticulum (HP:0002245)1.96526372
66Rough bone trabeculation (HP:0100670)1.94408919
67Deep palmar crease (HP:0006191)1.94269876
68Missing ribs (HP:0000921)1.91732611
69High anterior hairline (HP:0009890)1.91244005
70Cleft eyelid (HP:0000625)1.91162341
71Abnormality of the ileum (HP:0001549)1.88781528
72Aplasia/Hypoplasia of the uvula (HP:0010293)1.87508030
73Proximal placement of thumb (HP:0009623)1.86967737
74T lymphocytopenia (HP:0005403)1.86391539
75Breast hypoplasia (HP:0003187)1.85497925
76Hepatoblastoma (HP:0002884)1.85425916
77Poikiloderma (HP:0001029)1.84187792
78Neoplasm of the pancreas (HP:0002894)1.83795150
79Premature graying of hair (HP:0002216)1.82559329
80Respiratory difficulties (HP:0002880)1.82235464
81Elevated erythrocyte sedimentation rate (HP:0003565)1.82069402
82Bicuspid aortic valve (HP:0001647)1.80890754
83Lipid accumulation in hepatocytes (HP:0006561)1.80279236
84Absent septum pellucidum (HP:0001331)1.79742080
85Morphological abnormality of the inner ear (HP:0011390)1.79379593
86Aplasia/Hypoplasia of the thymus (HP:0010515)1.78896404
87Nephroblastoma (Wilms tumor) (HP:0002667)1.77973093
88Panhypogammaglobulinemia (HP:0003139)1.77899246
89Abnormality of the preputium (HP:0100587)1.77710675
90Anophthalmia (HP:0000528)1.76042048
91Recurrent viral infections (HP:0004429)1.75959696
92Volvulus (HP:0002580)1.75659024
93Partial duplication of thumb phalanx (HP:0009944)1.75477464
94Abnormality of T cells (HP:0002843)1.75017989
95Abnormality of the septum pellucidum (HP:0007375)1.73945899
96Partial duplication of the phalanx of hand (HP:0009999)1.73878753
97Exercise intolerance (HP:0003546)1.71263733
98Prominent nose (HP:0000448)1.71045772
99Patellar aplasia (HP:0006443)1.70894788
100Abnormality of T cell number (HP:0011839)1.70678354
101Nasolacrimal duct obstruction (HP:0000579)1.69841505
102Cellular immunodeficiency (HP:0005374)1.69070382
103B lymphocytopenia (HP:0010976)1.68461807
104Abnormality of B cell number (HP:0010975)1.68461807
105Medulloblastoma (HP:0002885)1.68280038
106Increased serum lactate (HP:0002151)1.67749958
107Overlapping toe (HP:0001845)1.65714815
1083-Methylglutaconic aciduria (HP:0003535)1.65517152
109Deviation of the thumb (HP:0009603)1.65175325
110Maternal diabetes (HP:0009800)1.64695245
111Microretrognathia (HP:0000308)1.64154894
112Abnormality of the lacrimal duct (HP:0011481)1.64071778
113Acute lymphatic leukemia (HP:0006721)1.63910336
114Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.63521757
115Impulsivity (HP:0100710)1.62208023
116Aplasia/Hypoplasia of the patella (HP:0006498)1.62081363
117Irregular epiphyses (HP:0010582)1.61342676
118Abnormality of chromosome stability (HP:0003220)1.61213394
119Abnormality of homocysteine metabolism (HP:0010919)1.61116769
120Homocystinuria (HP:0002156)1.61116769
121Hypoproteinemia (HP:0003075)1.60947397
122Short nose (HP:0003196)1.60727684
123Supernumerary bones of the axial skeleton (HP:0009144)1.59720257
124IgA deficiency (HP:0002720)1.58923570
125Carpal bone hypoplasia (HP:0001498)1.58730765
126Increased density of long bones (HP:0006392)1.57832020
127Facial cleft (HP:0002006)1.57743133
128Concave nail (HP:0001598)1.57232370
129Agnosia (HP:0010524)1.56666035
130Leukodystrophy (HP:0002415)1.56415588
131Supernumerary ribs (HP:0005815)1.56322587
132Optic nerve coloboma (HP:0000588)1.55157647
133Horseshoe kidney (HP:0000085)1.55049097
134Embryonal renal neoplasm (HP:0011794)1.54607474
135Progressive muscle weakness (HP:0003323)1.54466751
136Amaurosis fugax (HP:0100576)1.54381201
137Sparse scalp hair (HP:0002209)1.53880181
138Nasal polyposis (HP:0100582)1.51221007
139Ectopic kidney (HP:0000086)1.50916040
140Abnormality of cells of the lymphoid lineage (HP:0012140)1.50650589
141Premature ovarian failure (HP:0008209)1.50288715
142Seborrheic dermatitis (HP:0001051)1.50250203
143Neoplasm of the colon (HP:0100273)1.50093731
144Tracheoesophageal fistula (HP:0002575)1.49609827
145Lactic acidosis (HP:0003128)1.48602027
146Chromsome breakage (HP:0040012)1.48549850
147Short thumb (HP:0009778)1.48405968
148Abnormal lung lobation (HP:0002101)1.48229503
149Sparse eyelashes (HP:0000653)1.48094471
150Supernumerary spleens (HP:0009799)1.47929045
151Pulmonary fibrosis (HP:0002206)1.47770450
152Petechiae (HP:0000967)1.47712712
153Short middle phalanx of the 5th finger (HP:0004220)1.47643569
154Bilateral microphthalmos (HP:0007633)1.47280140
155Pancytopenia (HP:0001876)1.46644681
156Abnormality of small intestinal villus morphology (HP:0011472)1.44907934
157Villous atrophy (HP:0011473)1.44907934

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.40349067
2VRK23.66329533
3WEE13.13954172
4BUB13.01070186
5LRRK22.77853992
6RPS6KB22.71082925
7TLK12.64310583
8EEF2K2.61084523
9CDC72.54446995
10SRPK12.34231365
11MAP4K12.31928992
12TGFBR12.21122890
13MST42.08113971
14DYRK32.00049494
15VRK11.94824369
16ZAK1.88864249
17PASK1.87967404
18NEK21.87444626
19EIF2AK11.85388321
20STK161.81706439
21SMG11.79677298
22PIM21.78539857
23STK101.76770104
24MAP3K101.72864357
25TYRO31.67461249
26TRIB31.66228726
27TAF11.58568298
28ACVR1B1.55997725
29MKNK11.53661180
30AURKB1.49617528
31STK31.44309206
32RPS6KA41.42450692
33NEK11.37685295
34CDK71.35846773
35TTK1.25384668
36BTK1.25268335
37CDK41.24464353
38PKN21.23024243
39BRSK21.21738824
40EIF2AK31.20826489
41STK241.17935419
42KDR1.17484599
43KIT1.16804653
44TEC1.16216268
45FLT31.15103550
46NLK1.14859759
47ILK1.12355689
48BRAF1.12182187
49GRK61.11232274
50PLK11.10132034
51PRPF4B1.09171375
52PIM11.08235731
53ATR1.05306630
54TYK20.99980044
55CDK190.97670259
56MAPKAPK30.96461330
57CDK60.95615143
58WNK40.94067324
59MAP3K80.92233786
60MKNK20.87407095
61BLK0.87014863
62TSSK60.86615110
63PAK40.85320331
64ZAP700.85146601
65ITK0.83972281
66BRSK10.83376683
67TESK20.82642889
68EPHB20.81287425
69FGFR40.80001024
70ICK0.78917144
71TXK0.77804811
72STK40.77066629
73RPS6KL10.75006142
74RPS6KC10.75006142
75MATK0.74885442
76CHEK10.74381796
77CSNK2A20.72356866
78RPS6KA50.68810122
79RPS6KA60.68500051
80FGFR20.68427957
81AURKA0.67536224
82NME10.67352154
83SYK0.65865473
84EPHA20.65561692
85LCK0.64850604
86JAK30.64726883
87CHEK20.64368871
88IKBKB0.64216969
89PIK3CA0.61892409
90CSNK1E0.61214404
91PAK20.61085922
92CDK10.60014318
93CDK80.59773349
94SIK10.59683958
95DAPK30.57459550
96MAP3K30.55883907
97CSF1R0.55784391
98PBK0.54065976
99SCYL20.54039443
100LYN0.53999000
101CSNK2A10.53103265
102MELK0.53017521
103EIF2AK20.52309698
104CLK10.51913070
105ATM0.51741979
106CDK30.50521768
107BCKDK0.50212863
108PLK30.49571948
109RPS6KB10.49098909
110CDK20.47781063
111TBK10.46761294
112TGFBR20.45892592
113MARK30.45266831
114PAK10.44948324
115DYRK1B0.44709038
116PLK40.44622872
117CDK90.44401961
118MAP3K110.42995856
119ALK0.42952825
120CAMK1D0.42590051
121MAPK150.42542005
122MTOR0.42487601
123NUAK10.41499336
124MAP2K30.40922691
125AKT10.40285814
126MAP2K20.39648232
127FGFR10.39225377
128AKT20.38742586
129BRD40.37313594
130CCNB10.37265663
131FGFR30.37157566
132RPS6KA10.35722514
133PTK60.35607659
134CDK120.34782205
135ARAF0.34172043
136PNCK0.34152506
137MAPKAPK20.30872127
138RAF10.30283165
139DYRK20.30242312

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.65582303
2DNA replication_Homo sapiens_hsa030303.68181854
3Spliceosome_Homo sapiens_hsa030403.12747177
4Mismatch repair_Homo sapiens_hsa034303.12619806
5RNA polymerase_Homo sapiens_hsa030202.95803790
6Proteasome_Homo sapiens_hsa030502.69246605
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.55865028
8Homologous recombination_Homo sapiens_hsa034402.34249182
9RNA transport_Homo sapiens_hsa030132.23609583
10Nucleotide excision repair_Homo sapiens_hsa034202.20034139
11Base excision repair_Homo sapiens_hsa034102.15912344
12Pyrimidine metabolism_Homo sapiens_hsa002401.99936025
13Cell cycle_Homo sapiens_hsa041101.86212558
14Primary immunodeficiency_Homo sapiens_hsa053401.74138748
15Fanconi anemia pathway_Homo sapiens_hsa034601.68324521
16One carbon pool by folate_Homo sapiens_hsa006701.62213012
17Non-homologous end-joining_Homo sapiens_hsa034501.56721717
18RNA degradation_Homo sapiens_hsa030181.54168328
19p53 signaling pathway_Homo sapiens_hsa041151.42931733
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41217694
21Cardiac muscle contraction_Homo sapiens_hsa042601.38942475
22Systemic lupus erythematosus_Homo sapiens_hsa053221.34101592
23Protein export_Homo sapiens_hsa030601.33385190
24Basal transcription factors_Homo sapiens_hsa030221.32704196
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.31185034
26mRNA surveillance pathway_Homo sapiens_hsa030151.28252596
27Antigen processing and presentation_Homo sapiens_hsa046121.21017890
28Epstein-Barr virus infection_Homo sapiens_hsa051691.16756469
29Herpes simplex infection_Homo sapiens_hsa051681.11370797
30Parkinsons disease_Homo sapiens_hsa050121.09758727
31Hematopoietic cell lineage_Homo sapiens_hsa046401.01397592
32Oxidative phosphorylation_Homo sapiens_hsa001901.00880433
33Huntingtons disease_Homo sapiens_hsa050160.98542148
34Viral carcinogenesis_Homo sapiens_hsa052030.96204150
35Transcriptional misregulation in cancer_Homo sapiens_hsa052020.92269522
36Purine metabolism_Homo sapiens_hsa002300.88977275
37Small cell lung cancer_Homo sapiens_hsa052220.87505787
38NF-kappa B signaling pathway_Homo sapiens_hsa040640.87472750
39HTLV-I infection_Homo sapiens_hsa051660.86740935
40Intestinal immune network for IgA production_Homo sapiens_hsa046720.85469526
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83062401
42Biosynthesis of amino acids_Homo sapiens_hsa012300.82764610
43Measles_Homo sapiens_hsa051620.78206696
44Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.75299998
45Basal cell carcinoma_Homo sapiens_hsa052170.73923675
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.73188517
47T cell receptor signaling pathway_Homo sapiens_hsa046600.72689331
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69815024
49Colorectal cancer_Homo sapiens_hsa052100.68655023
50Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66169482
51B cell receptor signaling pathway_Homo sapiens_hsa046620.65373787
52Alzheimers disease_Homo sapiens_hsa050100.63573896
53MicroRNAs in cancer_Homo sapiens_hsa052060.63401340
54Carbon metabolism_Homo sapiens_hsa012000.62308138
55Pyruvate metabolism_Homo sapiens_hsa006200.61764638
56Apoptosis_Homo sapiens_hsa042100.60267483
57Hepatitis B_Homo sapiens_hsa051610.60252172
58Vitamin digestion and absorption_Homo sapiens_hsa049770.59914708
59Notch signaling pathway_Homo sapiens_hsa043300.59052286
60Cyanoamino acid metabolism_Homo sapiens_hsa004600.58588707
61Viral myocarditis_Homo sapiens_hsa054160.58410162
62Allograft rejection_Homo sapiens_hsa053300.57181765
63Thyroid cancer_Homo sapiens_hsa052160.56828685
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.56325317
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.55825448
66Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55396215
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.55125816
68Legionellosis_Homo sapiens_hsa051340.54575831
69Asthma_Homo sapiens_hsa053100.53035748
70Chronic myeloid leukemia_Homo sapiens_hsa052200.52653156
71Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52204293
72Acute myeloid leukemia_Homo sapiens_hsa052210.51509231
73Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50945626
74Alcoholism_Homo sapiens_hsa050340.50765827
75Leishmaniasis_Homo sapiens_hsa051400.50698259
76Non-small cell lung cancer_Homo sapiens_hsa052230.50559794
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.49841202
78Pathways in cancer_Homo sapiens_hsa052000.48454772
79Toxoplasmosis_Homo sapiens_hsa051450.47843665
80Folate biosynthesis_Homo sapiens_hsa007900.47378952
81Leukocyte transendothelial migration_Homo sapiens_hsa046700.46289110
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46274087
83TGF-beta signaling pathway_Homo sapiens_hsa043500.46166061
84Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.45810600
85Hippo signaling pathway_Homo sapiens_hsa043900.44592334
86Sulfur relay system_Homo sapiens_hsa041220.44565617
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43851031
88RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.43634609
89Shigellosis_Homo sapiens_hsa051310.43464437
90Lysine degradation_Homo sapiens_hsa003100.43398259
91Graft-versus-host disease_Homo sapiens_hsa053320.42875474
92N-Glycan biosynthesis_Homo sapiens_hsa005100.42521088
93Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41920726
94Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41910084
95Metabolic pathways_Homo sapiens_hsa011000.41692490
96Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.41533526
97Selenocompound metabolism_Homo sapiens_hsa004500.40964935
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38122311
99Oocyte meiosis_Homo sapiens_hsa041140.35382651
100AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35093193
101Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34732918
102Influenza A_Homo sapiens_hsa051640.34623791
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33847816
104Wnt signaling pathway_Homo sapiens_hsa043100.32416206
105Platelet activation_Homo sapiens_hsa046110.32381095
106Steroid biosynthesis_Homo sapiens_hsa001000.32301929
107Hedgehog signaling pathway_Homo sapiens_hsa043400.32091709
108Bladder cancer_Homo sapiens_hsa052190.31751953
109Osteoclast differentiation_Homo sapiens_hsa043800.31605751
110Autoimmune thyroid disease_Homo sapiens_hsa053200.31070169
111Endometrial cancer_Homo sapiens_hsa052130.31022444
112Pentose phosphate pathway_Homo sapiens_hsa000300.30130050
113Fat digestion and absorption_Homo sapiens_hsa049750.28370497
114Pancreatic cancer_Homo sapiens_hsa052120.27282693
115Proteoglycans in cancer_Homo sapiens_hsa052050.27046290
116Renal cell carcinoma_Homo sapiens_hsa052110.26524130
117Adherens junction_Homo sapiens_hsa045200.25521152
118HIF-1 signaling pathway_Homo sapiens_hsa040660.25427286
119Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.24840057
120Propanoate metabolism_Homo sapiens_hsa006400.24288112
121Prostate cancer_Homo sapiens_hsa052150.23660892
122Glutathione metabolism_Homo sapiens_hsa004800.23414391
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20932459
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.17751903
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.17737208
1262-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.16786234
127VEGF signaling pathway_Homo sapiens_hsa043700.16742203
128Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.15158031
129Fructose and mannose metabolism_Homo sapiens_hsa000510.13022198
130Drug metabolism - other enzymes_Homo sapiens_hsa009830.12854191
131Pentose and glucuronate interconversions_Homo sapiens_hsa000400.12759161
132Melanoma_Homo sapiens_hsa052180.11307795
133mTOR signaling pathway_Homo sapiens_hsa041500.10628657
134FoxO signaling pathway_Homo sapiens_hsa040680.10311794
135Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.10154660

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