

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 9.69811205 |
| 2 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 8.85597700 |
| 3 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 8.77547159 |
| 4 | regulation of hypersensitivity (GO:0002883) | 7.95335382 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 7.26341523 |
| 6 | positive regulation of mast cell degranulation (GO:0043306) | 6.75588890 |
| 7 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 6.75588890 |
| 8 | behavioral response to nicotine (GO:0035095) | 6.40680482 |
| 9 | viral transcription (GO:0019083) | 6.36730528 |
| 10 | maturation of SSU-rRNA (GO:0030490) | 6.25351527 |
| 11 | translational termination (GO:0006415) | 6.14045419 |
| 12 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 5.94860107 |
| 13 | protein neddylation (GO:0045116) | 5.49289955 |
| 14 | positive regulation of mast cell activation (GO:0033005) | 5.49140518 |
| 15 | ribosomal small subunit biogenesis (GO:0042274) | 5.21940655 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.18368587 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 5.14476903 |
| 18 | protein targeting to ER (GO:0045047) | 5.07050552 |
| 19 | translational elongation (GO:0006414) | 5.03658717 |
| 20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.84078203 |
| 21 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 4.83748384 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.81831343 |
| 23 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.69048101 |
| 24 | viral life cycle (GO:0019058) | 4.68040286 |
| 25 | protein localization to endoplasmic reticulum (GO:0070972) | 4.67462269 |
| 26 | regulation of inflammatory response to antigenic stimulus (GO:0002861) | 4.50555019 |
| 27 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.41472699 |
| 28 | ATP synthesis coupled proton transport (GO:0015986) | 4.41472699 |
| 29 | positive regulation of leukocyte degranulation (GO:0043302) | 4.15380396 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 4.11529499 |
| 31 | regulation of chronic inflammatory response (GO:0002676) | 4.09702061 |
| 32 | protein complex disassembly (GO:0043241) | 4.00592904 |
| 33 | translational initiation (GO:0006413) | 3.96688115 |
| 34 | macromolecular complex disassembly (GO:0032984) | 3.87418341 |
| 35 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.80914062 |
| 36 | synaptic transmission, cholinergic (GO:0007271) | 3.62227485 |
| 37 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.58681688 |
| 38 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 3.52838141 |
| 39 | microtubule severing (GO:0051013) | 3.37741316 |
| 40 | prepulse inhibition (GO:0060134) | 3.35972076 |
| 41 | positive regulation of B cell mediated immunity (GO:0002714) | 3.35232348 |
| 42 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.35232348 |
| 43 | protein targeting to membrane (GO:0006612) | 3.34821637 |
| 44 | monoamine transport (GO:0015844) | 3.34177199 |
| 45 | positive regulation of regulated secretory pathway (GO:1903307) | 3.32291757 |
| 46 | viral protein processing (GO:0019082) | 3.31916395 |
| 47 | endoderm formation (GO:0001706) | 3.27675298 |
| 48 | cell proliferation in forebrain (GO:0021846) | 3.26483647 |
| 49 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.26047416 |
| 50 | respiratory electron transport chain (GO:0022904) | 3.21903333 |
| 51 | axonal fasciculation (GO:0007413) | 3.17253077 |
| 52 | positive regulation of protein homooligomerization (GO:0032464) | 3.12716721 |
| 53 | electron transport chain (GO:0022900) | 3.12651946 |
| 54 | mRNA catabolic process (GO:0006402) | 3.10029443 |
| 55 | translation (GO:0006412) | 3.08771514 |
| 56 | sleep (GO:0030431) | 3.03608565 |
| 57 | mitochondrion morphogenesis (GO:0070584) | 3.03596043 |
| 58 | ribosomal large subunit biogenesis (GO:0042273) | 3.02181801 |
| 59 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.01515104 |
| 60 | piRNA metabolic process (GO:0034587) | 2.97993230 |
| 61 | short-term memory (GO:0007614) | 2.86116140 |
| 62 | rRNA catabolic process (GO:0016075) | 2.83449069 |
| 63 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.79528527 |
| 64 | GTP biosynthetic process (GO:0006183) | 2.79421009 |
| 65 | cellular response to ATP (GO:0071318) | 2.78228851 |
| 66 | positive regulation of protein depolymerization (GO:1901881) | 2.77325811 |
| 67 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.73716990 |
| 68 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.73459646 |
| 69 | synaptic transmission, glutamatergic (GO:0035249) | 2.73239685 |
| 70 | RNA catabolic process (GO:0006401) | 2.72039761 |
| 71 | neuromuscular synaptic transmission (GO:0007274) | 2.71868147 |
| 72 | neuron recognition (GO:0008038) | 2.71193598 |
| 73 | T-helper 1 type immune response (GO:0042088) | 2.70316758 |
| 74 | nucleotide transmembrane transport (GO:1901679) | 2.70221025 |
| 75 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.68957010 |
| 76 | positive regulation of microtubule polymerization or depolymerization (GO:0031112) | 2.67430567 |
| 77 | olfactory bulb development (GO:0021772) | 2.67205008 |
| 78 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.66006604 |
| 79 | positive regulation of respiratory burst (GO:0060267) | 2.65977768 |
| 80 | positive regulation of mitochondrial fission (GO:0090141) | 2.61014838 |
| 81 | leukotriene biosynthetic process (GO:0019370) | 2.60999872 |
| 82 | regulation of mast cell degranulation (GO:0043304) | 2.60936468 |
| 83 | protein-cofactor linkage (GO:0018065) | 2.58622960 |
| 84 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.58155031 |
| 85 | dendritic spine morphogenesis (GO:0060997) | 2.56078185 |
| 86 | gamma-aminobutyric acid transport (GO:0015812) | 2.54293063 |
| 87 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.52622845 |
| 88 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.52480630 |
| 89 | ATP biosynthetic process (GO:0006754) | 2.51439459 |
| 90 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.50441712 |
| 91 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.49971638 |
| 92 | meiotic cell cycle (GO:0051321) | 2.47908009 |
| 93 | proton transport (GO:0015992) | 2.46332056 |
| 94 | positive regulation of interleukin-17 production (GO:0032740) | 2.44758045 |
| 95 | hydrogen transport (GO:0006818) | 2.44338262 |
| 96 | inner mitochondrial membrane organization (GO:0007007) | 2.44216521 |
| 97 | somite development (GO:0061053) | 2.43584556 |
| 98 | cardiovascular system development (GO:0072358) | 2.43406424 |
| 99 | thyroid hormone generation (GO:0006590) | 2.42532450 |
| 100 | positive regulation of activated T cell proliferation (GO:0042104) | 2.38978843 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.79685643 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.21571105 |
| 3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.06570027 |
| 4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.92037106 |
| 5 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.82191887 |
| 6 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.54606117 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.53266729 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.47482366 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.47063130 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.32704292 |
| 11 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.15585997 |
| 12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.08262497 |
| 13 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.02328777 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.01633118 |
| 15 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.00492825 |
| 16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.94894053 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.91245800 |
| 18 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.84063735 |
| 19 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.83935450 |
| 20 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.74804403 |
| 21 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.73958102 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.68306499 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66561744 |
| 24 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.64183036 |
| 25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.63481807 |
| 26 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.57464108 |
| 27 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.56742628 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.56044655 |
| 29 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.55274128 |
| 30 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.55012936 |
| 31 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.52801262 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51824134 |
| 33 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.51314111 |
| 34 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.48391708 |
| 35 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.45520626 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.44146285 |
| 37 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.42946404 |
| 38 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.37721376 |
| 39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.36785350 |
| 40 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.36313242 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34886010 |
| 42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.30870057 |
| 43 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.26613023 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25529749 |
| 45 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.25391654 |
| 46 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.25081952 |
| 47 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.24711280 |
| 48 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.24378712 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.22259153 |
| 50 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.21577531 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.21184606 |
| 52 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.20065103 |
| 53 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.19798368 |
| 54 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.18580576 |
| 55 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.16533031 |
| 56 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.16275377 |
| 57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.15611858 |
| 58 | ERA_21632823_ChIP-Seq_H3396_Human | 1.15173716 |
| 59 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.14580010 |
| 60 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.13647093 |
| 61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.13636155 |
| 62 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.13236799 |
| 63 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.11123887 |
| 64 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.09087170 |
| 65 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07699429 |
| 66 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.07663873 |
| 67 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.07521282 |
| 68 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06956123 |
| 69 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06956123 |
| 70 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06904206 |
| 71 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.04286864 |
| 72 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.03872979 |
| 73 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.03385489 |
| 74 | FUS_26573619_Chip-Seq_HEK293_Human | 1.03374774 |
| 75 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02059326 |
| 76 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.01673999 |
| 77 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.01016806 |
| 78 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.01016193 |
| 79 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.00856554 |
| 80 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.99108739 |
| 81 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98475965 |
| 82 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.98375963 |
| 83 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98275639 |
| 84 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.97006831 |
| 85 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96493142 |
| 86 | EWS_26573619_Chip-Seq_HEK293_Human | 0.94925276 |
| 87 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.94211759 |
| 88 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.93616154 |
| 89 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.93039935 |
| 90 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.92452032 |
| 91 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.92237015 |
| 92 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.92237015 |
| 93 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.91107372 |
| 94 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.90737813 |
| 95 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.90059045 |
| 96 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.90059045 |
| 97 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 0.89849814 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.89163999 |
| 99 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88479749 |
| 100 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.86951145 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.91444300 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.81831445 |
| 3 | MP0004142_abnormal_muscle_tone | 3.24595384 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.22873392 |
| 5 | MP0003787_abnormal_imprinting | 3.17021581 |
| 6 | MP0003122_maternal_imprinting | 2.83353459 |
| 7 | MP0003646_muscle_fatigue | 2.80360966 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.56995569 |
| 9 | MP0003121_genomic_imprinting | 2.40628447 |
| 10 | MP0001873_stomach_inflammation | 2.19553244 |
| 11 | MP0001986_abnormal_taste_sensitivity | 2.12005442 |
| 12 | MP0002638_abnormal_pupillary_reflex | 2.09727227 |
| 13 | MP0000778_abnormal_nervous_system | 2.09389803 |
| 14 | MP0002272_abnormal_nervous_system | 2.03551077 |
| 15 | MP0009764_decreased_sensitivity_to | 1.99269161 |
| 16 | MP0002102_abnormal_ear_morphology | 1.98227493 |
| 17 | MP0005360_urolithiasis | 1.86252258 |
| 18 | MP0009046_muscle_twitch | 1.85629304 |
| 19 | MP0002277_abnormal_respiratory_mucosa | 1.79330912 |
| 20 | MP0001485_abnormal_pinna_reflex | 1.76561234 |
| 21 | MP0003123_paternal_imprinting | 1.71403720 |
| 22 | MP0008872_abnormal_physiological_respon | 1.70903072 |
| 23 | MP0000427_abnormal_hair_cycle | 1.61672058 |
| 24 | MP0005423_abnormal_somatic_nervous | 1.61384076 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.61376452 |
| 26 | MP0004859_abnormal_synaptic_plasticity | 1.54588021 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.54231129 |
| 28 | MP0000537_abnormal_urethra_morphology | 1.52683097 |
| 29 | MP0005167_abnormal_blood-brain_barrier | 1.52370075 |
| 30 | MP0006072_abnormal_retinal_apoptosis | 1.50613726 |
| 31 | MP0004742_abnormal_vestibular_system | 1.49374739 |
| 32 | MP0005499_abnormal_olfactory_system | 1.47246003 |
| 33 | MP0005394_taste/olfaction_phenotype | 1.47246003 |
| 34 | MP0001293_anophthalmia | 1.44615657 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.44255152 |
| 36 | MP0003136_yellow_coat_color | 1.42960051 |
| 37 | MP0010386_abnormal_urinary_bladder | 1.41652276 |
| 38 | MP0005377_hearing/vestibular/ear_phenot | 1.41132700 |
| 39 | MP0003878_abnormal_ear_physiology | 1.41132700 |
| 40 | MP0005645_abnormal_hypothalamus_physiol | 1.39874083 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.38928635 |
| 42 | MP0008789_abnormal_olfactory_epithelium | 1.33796817 |
| 43 | MP0005389_reproductive_system_phenotype | 1.24870531 |
| 44 | MP0002184_abnormal_innervation | 1.23756875 |
| 45 | MP0005195_abnormal_posterior_eye | 1.23208222 |
| 46 | MP0000955_abnormal_spinal_cord | 1.22905911 |
| 47 | MP0001919_abnormal_reproductive_system | 1.19346927 |
| 48 | MP0003635_abnormal_synaptic_transmissio | 1.18825210 |
| 49 | MP0002734_abnormal_mechanical_nocicepti | 1.17604143 |
| 50 | MP0001188_hyperpigmentation | 1.17585974 |
| 51 | MP0002735_abnormal_chemical_nociception | 1.16289537 |
| 52 | MP0009745_abnormal_behavioral_response | 1.15321042 |
| 53 | MP0002572_abnormal_emotion/affect_behav | 1.13669005 |
| 54 | MP0001968_abnormal_touch/_nociception | 1.12938079 |
| 55 | MP0004270_analgesia | 1.12479906 |
| 56 | MP0001970_abnormal_pain_threshold | 1.12375745 |
| 57 | MP0002557_abnormal_social/conspecific_i | 1.11274461 |
| 58 | MP0002148_abnormal_hypersensitivity_rea | 1.06707549 |
| 59 | MP0000685_abnormal_immune_system | 1.06308226 |
| 60 | MP0005670_abnormal_white_adipose | 1.05469798 |
| 61 | MP0000631_abnormal_neuroendocrine_gland | 1.04715179 |
| 62 | MP0001984_abnormal_olfaction | 1.04421591 |
| 63 | MP0002653_abnormal_ependyma_morphology | 1.04139830 |
| 64 | MP0002752_abnormal_somatic_nervous | 1.03750423 |
| 65 | MP0003315_abnormal_perineum_morphology | 1.03301743 |
| 66 | MP0008775_abnormal_heart_ventricle | 0.99861165 |
| 67 | MP0001348_abnormal_lacrimal_gland | 0.99834346 |
| 68 | MP0005084_abnormal_gallbladder_morpholo | 0.99710318 |
| 69 | MP0005448_abnormal_energy_balance | 0.98369591 |
| 70 | MP0001663_abnormal_digestive_system | 0.97874205 |
| 71 | MP0004885_abnormal_endolymph | 0.97073646 |
| 72 | MP0001440_abnormal_grooming_behavior | 0.96752991 |
| 73 | MP0002160_abnormal_reproductive_system | 0.96417854 |
| 74 | MP0008875_abnormal_xenobiotic_pharmacok | 0.95391492 |
| 75 | MP0001501_abnormal_sleep_pattern | 0.95354365 |
| 76 | MP0000516_abnormal_urinary_system | 0.95183291 |
| 77 | MP0005367_renal/urinary_system_phenotyp | 0.95183291 |
| 78 | MP0002882_abnormal_neuron_morphology | 0.94808970 |
| 79 | MP0003880_abnormal_central_pattern | 0.93747271 |
| 80 | MP0000049_abnormal_middle_ear | 0.93635037 |
| 81 | MP0001324_abnormal_eye_pigmentation | 0.91973929 |
| 82 | MP0000465_gastrointestinal_hemorrhage | 0.91954209 |
| 83 | MP0002733_abnormal_thermal_nociception | 0.90612716 |
| 84 | MP0002063_abnormal_learning/memory/cond | 0.87147328 |
| 85 | MP0002095_abnormal_skin_pigmentation | 0.86912170 |
| 86 | MP0002067_abnormal_sensory_capabilities | 0.85995655 |
| 87 | MP0001502_abnormal_circadian_rhythm | 0.85487026 |
| 88 | MP0003195_calcinosis | 0.84220264 |
| 89 | MP0001963_abnormal_hearing_physiology | 0.83341455 |
| 90 | MP0001756_abnormal_urination | 0.82536173 |
| 91 | MP0001542_abnormal_bone_strength | 0.80178265 |
| 92 | MP0003942_abnormal_urinary_system | 0.80044967 |
| 93 | MP0005410_abnormal_fertilization | 0.78209271 |
| 94 | MP0001486_abnormal_startle_reflex | 0.76725082 |
| 95 | MP0004811_abnormal_neuron_physiology | 0.76720413 |
| 96 | MP0006035_abnormal_mitochondrial_morpho | 0.74954388 |
| 97 | MP0003690_abnormal_glial_cell | 0.72297010 |
| 98 | MP0002210_abnormal_sex_determination | 0.71175087 |
| 99 | MP0000026_abnormal_inner_ear | 0.70484833 |
| 100 | MP0001286_abnormal_eye_development | 0.70428392 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.99713488 |
| 2 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 5.34612285 |
| 3 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 5.34612285 |
| 4 | Abnormality of the corticospinal tract (HP:0002492) | 4.74234676 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.70003547 |
| 6 | Myokymia (HP:0002411) | 4.45249391 |
| 7 | Septo-optic dysplasia (HP:0100842) | 4.31993346 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.20150929 |
| 9 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.12197027 |
| 10 | Genetic anticipation (HP:0003743) | 4.09113589 |
| 11 | Acute encephalopathy (HP:0006846) | 4.05059877 |
| 12 | Agitation (HP:0000713) | 3.85181271 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.82319235 |
| 14 | Papilledema (HP:0001085) | 3.73498697 |
| 15 | Stenosis of the external auditory canal (HP:0000402) | 3.59255367 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.28920085 |
| 17 | Increased CSF lactate (HP:0002490) | 3.16494370 |
| 18 | Absent thumb (HP:0009777) | 3.13128101 |
| 19 | Macrocytic anemia (HP:0001972) | 2.89051828 |
| 20 | Absent septum pellucidum (HP:0001331) | 2.86383387 |
| 21 | Keratoconus (HP:0000563) | 2.85404791 |
| 22 | Increased corneal curvature (HP:0100692) | 2.85404791 |
| 23 | Restlessness (HP:0000711) | 2.85380793 |
| 24 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.82986800 |
| 25 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.81068789 |
| 26 | Cerebral edema (HP:0002181) | 2.75670558 |
| 27 | Insidious onset (HP:0003587) | 2.73909238 |
| 28 | Termporal pattern (HP:0011008) | 2.73909238 |
| 29 | Polyphagia (HP:0002591) | 2.73369840 |
| 30 | Hepatocellular necrosis (HP:0001404) | 2.69594205 |
| 31 | Medial flaring of the eyebrow (HP:0010747) | 2.65791305 |
| 32 | Pallor (HP:0000980) | 2.64358454 |
| 33 | Enlarged penis (HP:0000040) | 2.64074533 |
| 34 | Abnormal hemoglobin (HP:0011902) | 2.62461722 |
| 35 | Humeroradial synostosis (HP:0003041) | 2.60049075 |
| 36 | Synostosis involving the elbow (HP:0003938) | 2.60049075 |
| 37 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.56835733 |
| 38 | Anterior segment dysgenesis (HP:0007700) | 2.56728002 |
| 39 | Optic disc pallor (HP:0000543) | 2.50777260 |
| 40 | Decreased central vision (HP:0007663) | 2.50454104 |
| 41 | Abnormality of the labia minora (HP:0012880) | 2.45398965 |
| 42 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.42136125 |
| 43 | Abnormality of alanine metabolism (HP:0010916) | 2.42136125 |
| 44 | Hyperalaninemia (HP:0003348) | 2.42136125 |
| 45 | Type II lissencephaly (HP:0007260) | 2.40436369 |
| 46 | Disinhibition (HP:0000734) | 2.28454036 |
| 47 | Abnormality of the septum pellucidum (HP:0007375) | 2.27803265 |
| 48 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.26527226 |
| 49 | Horseshoe kidney (HP:0000085) | 2.26189379 |
| 50 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.22990517 |
| 51 | Congenital, generalized hypertrichosis (HP:0004540) | 2.20729159 |
| 52 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.18500059 |
| 53 | Hyperglycinemia (HP:0002154) | 2.16921617 |
| 54 | Lissencephaly (HP:0001339) | 2.16765361 |
| 55 | Impulsivity (HP:0100710) | 2.16482408 |
| 56 | Abnormal number of erythroid precursors (HP:0012131) | 2.15823640 |
| 57 | Pendular nystagmus (HP:0012043) | 2.15082668 |
| 58 | Adrenal hypoplasia (HP:0000835) | 2.11307287 |
| 59 | Hepatic necrosis (HP:0002605) | 2.11101575 |
| 60 | Growth hormone deficiency (HP:0000824) | 2.06424952 |
| 61 | Optic nerve hypoplasia (HP:0000609) | 2.01360789 |
| 62 | Hyperthyroidism (HP:0000836) | 1.96892563 |
| 63 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.96331063 |
| 64 | Failure to thrive in infancy (HP:0001531) | 1.96012911 |
| 65 | Abnormality of reticulocytes (HP:0004312) | 1.91765758 |
| 66 | Hypoplasia of the radius (HP:0002984) | 1.90650202 |
| 67 | Maternal diabetes (HP:0009800) | 1.87079396 |
| 68 | Thyroid-stimulating hormone excess (HP:0002925) | 1.85737806 |
| 69 | Small hand (HP:0200055) | 1.84230198 |
| 70 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.83413339 |
| 71 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.83306282 |
| 72 | Diastasis recti (HP:0001540) | 1.82111997 |
| 73 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.80265868 |
| 74 | Myotonia (HP:0002486) | 1.79241844 |
| 75 | Leukodystrophy (HP:0002415) | 1.78660981 |
| 76 | Abnormality of the nasal septum (HP:0000419) | 1.77503725 |
| 77 | Confusion (HP:0001289) | 1.75837673 |
| 78 | Pancreatic cysts (HP:0001737) | 1.75730717 |
| 79 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.75521860 |
| 80 | Fetal akinesia sequence (HP:0001989) | 1.74859664 |
| 81 | CNS demyelination (HP:0007305) | 1.74568489 |
| 82 | Chronic hepatic failure (HP:0100626) | 1.74293973 |
| 83 | Increased hepatocellular lipid droplets (HP:0006565) | 1.73947784 |
| 84 | Chorioretinal atrophy (HP:0000533) | 1.72915884 |
| 85 | Increased serum lactate (HP:0002151) | 1.72595932 |
| 86 | Submucous cleft hard palate (HP:0000176) | 1.71297974 |
| 87 | Hypoplasia of the ulna (HP:0003022) | 1.70760313 |
| 88 | Inappropriate behavior (HP:0000719) | 1.70296499 |
| 89 | Respiratory failure (HP:0002878) | 1.70288307 |
| 90 | Severe muscular hypotonia (HP:0006829) | 1.70117447 |
| 91 | Colon cancer (HP:0003003) | 1.69733701 |
| 92 | Esotropia (HP:0000565) | 1.69583234 |
| 93 | Forearm undergrowth (HP:0009821) | 1.69294169 |
| 94 | Hyperphosphatemia (HP:0002905) | 1.69017107 |
| 95 | Protruding tongue (HP:0010808) | 1.68747981 |
| 96 | Cerebellar dysplasia (HP:0007033) | 1.68648695 |
| 97 | Methylmalonic aciduria (HP:0012120) | 1.68589122 |
| 98 | Lipid accumulation in hepatocytes (HP:0006561) | 1.68443522 |
| 99 | Supernumerary ribs (HP:0005815) | 1.66569701 |
| 100 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.66183446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 4.44368493 |
| 2 | EPHB2 | 3.53282566 |
| 3 | MAP3K11 | 3.15549042 |
| 4 | CDK19 | 3.04565195 |
| 5 | SRPK1 | 2.86105896 |
| 6 | WNK4 | 2.82665654 |
| 7 | MARK3 | 2.41747474 |
| 8 | PIK3CA | 2.28204395 |
| 9 | NME1 | 2.21294782 |
| 10 | TAOK3 | 2.16465188 |
| 11 | MARK1 | 2.06450805 |
| 12 | STK39 | 1.88682428 |
| 13 | PINK1 | 1.87341363 |
| 14 | MAP2K7 | 1.79427741 |
| 15 | DYRK2 | 1.76621865 |
| 16 | FRK | 1.72386342 |
| 17 | OXSR1 | 1.66796669 |
| 18 | MAP4K2 | 1.62996315 |
| 19 | CSNK1G2 | 1.60466492 |
| 20 | NTRK2 | 1.59353243 |
| 21 | TLK1 | 1.59205099 |
| 22 | MAP3K9 | 1.58739001 |
| 23 | CASK | 1.55549586 |
| 24 | PRKCG | 1.54043519 |
| 25 | TNIK | 1.43294870 |
| 26 | GRK1 | 1.33916181 |
| 27 | MAP3K4 | 1.32292093 |
| 28 | KSR1 | 1.31857342 |
| 29 | ARAF | 1.31113566 |
| 30 | TRIM28 | 1.24850106 |
| 31 | MAP4K1 | 1.15849194 |
| 32 | CAMKK1 | 1.13797852 |
| 33 | DYRK1B | 1.13765261 |
| 34 | MINK1 | 1.12944085 |
| 35 | SIK2 | 1.07405589 |
| 36 | PRKCQ | 1.06788167 |
| 37 | MAPK13 | 1.05654905 |
| 38 | CAMKK2 | 1.03231075 |
| 39 | PRKCZ | 0.98225127 |
| 40 | PHKG2 | 0.97561824 |
| 41 | PHKG1 | 0.97561824 |
| 42 | TNK2 | 0.95884965 |
| 43 | ICK | 0.94504642 |
| 44 | ADRBK2 | 0.85886581 |
| 45 | MAP3K2 | 0.84040482 |
| 46 | LRRK2 | 0.83638573 |
| 47 | PRKCH | 0.83574981 |
| 48 | INSRR | 0.82177511 |
| 49 | PRKCI | 0.80059770 |
| 50 | WNK3 | 0.77365247 |
| 51 | CDK3 | 0.73256541 |
| 52 | PAK3 | 0.72841126 |
| 53 | CSNK1G3 | 0.72522667 |
| 54 | EIF2AK2 | 0.72040338 |
| 55 | MAP3K6 | 0.70464370 |
| 56 | MAP2K4 | 0.69837427 |
| 57 | PRKCD | 0.69517002 |
| 58 | BRAF | 0.69360322 |
| 59 | TEC | 0.68529296 |
| 60 | PIM2 | 0.67647361 |
| 61 | NUAK1 | 0.66517792 |
| 62 | BCR | 0.63387806 |
| 63 | PRKCE | 0.62178064 |
| 64 | WNK1 | 0.61504863 |
| 65 | CSNK2A2 | 0.61355426 |
| 66 | CSNK1A1L | 0.61317457 |
| 67 | CAMK1 | 0.60474377 |
| 68 | PRKACA | 0.56524356 |
| 69 | NEK1 | 0.53508830 |
| 70 | RPS6KA5 | 0.53418368 |
| 71 | PDK2 | 0.52658456 |
| 72 | MAPK15 | 0.52642009 |
| 73 | SIK1 | 0.52490448 |
| 74 | OBSCN | 0.52180048 |
| 75 | CSNK1E | 0.50768386 |
| 76 | AURKA | 0.50586633 |
| 77 | PRKG1 | 0.48157242 |
| 78 | RPS6KA6 | 0.47816880 |
| 79 | ADRBK1 | 0.47666203 |
| 80 | LIMK1 | 0.47535931 |
| 81 | DAPK3 | 0.47418965 |
| 82 | CSNK1G1 | 0.45603016 |
| 83 | CDK14 | 0.44559121 |
| 84 | PIK3CG | 0.44283883 |
| 85 | DYRK1A | 0.43586099 |
| 86 | STK11 | 0.42510606 |
| 87 | GRK7 | 0.42023017 |
| 88 | MAPKAPK3 | 0.41809140 |
| 89 | BMX | 0.41752464 |
| 90 | ERBB2 | 0.40074536 |
| 91 | IKBKB | 0.38199647 |
| 92 | CSNK2A1 | 0.37747566 |
| 93 | CAMK2A | 0.37072737 |
| 94 | PRKAA1 | 0.35010638 |
| 95 | CSNK1A1 | 0.34844008 |
| 96 | NEK2 | 0.34657132 |
| 97 | PRKCA | 0.34454106 |
| 98 | CDK11A | 0.33607921 |
| 99 | CSNK1D | 0.32876476 |
| 100 | IRAK4 | 0.30968361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.72950628 |
| 2 | Asthma_Homo sapiens_hsa05310 | 5.03692104 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.75261390 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.31587153 |
| 5 | Nicotine addiction_Homo sapiens_hsa05033 | 2.97384052 |
| 6 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.47997987 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.32097082 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.29324357 |
| 9 | Phototransduction_Homo sapiens_hsa04744 | 2.25575836 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.16749803 |
| 11 | Sulfur relay system_Homo sapiens_hsa04122 | 2.09085090 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.06374439 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 1.99038383 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.87608319 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.83663521 |
| 16 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.65293897 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.60045388 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.59870934 |
| 19 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.59831059 |
| 20 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.54318026 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.52504350 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.47095800 |
| 23 | Morphine addiction_Homo sapiens_hsa05032 | 1.38071702 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.32080940 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.29666684 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.23334450 |
| 27 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.14387834 |
| 28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.07920234 |
| 29 | Insulin secretion_Homo sapiens_hsa04911 | 1.05669977 |
| 30 | Allograft rejection_Homo sapiens_hsa05330 | 1.03101716 |
| 31 | Cocaine addiction_Homo sapiens_hsa05030 | 1.02529313 |
| 32 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.02267109 |
| 33 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.02107795 |
| 34 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.97068664 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.96938039 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89986255 |
| 37 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.88440150 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.87623444 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 0.84536777 |
| 40 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.82217453 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82058455 |
| 42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.81236058 |
| 43 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.80211148 |
| 44 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.79238655 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79007600 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.76926578 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76045909 |
| 48 | Salivary secretion_Homo sapiens_hsa04970 | 0.75794150 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.73314985 |
| 50 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.73240275 |
| 51 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.72009701 |
| 52 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.70573286 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.70045070 |
| 54 | GABAergic synapse_Homo sapiens_hsa04727 | 0.69987649 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.69341522 |
| 56 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69154973 |
| 57 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.68356744 |
| 58 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.66796704 |
| 59 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.64843351 |
| 60 | Olfactory transduction_Homo sapiens_hsa04740 | 0.64004888 |
| 61 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.63684273 |
| 62 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.62401749 |
| 63 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.62235580 |
| 64 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.61167302 |
| 65 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.56287826 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54094491 |
| 67 | Homologous recombination_Homo sapiens_hsa03440 | 0.53120828 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.52030449 |
| 69 | Axon guidance_Homo sapiens_hsa04360 | 0.50643186 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50317944 |
| 71 | Histidine metabolism_Homo sapiens_hsa00340 | 0.48710054 |
| 72 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.45698354 |
| 73 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.45642194 |
| 74 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.45167203 |
| 75 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44964850 |
| 76 | Mineral absorption_Homo sapiens_hsa04978 | 0.43552092 |
| 77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.41791151 |
| 78 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41662581 |
| 79 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.40911348 |
| 80 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.40670167 |
| 81 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39004429 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38940920 |
| 83 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38918131 |
| 84 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.38319458 |
| 85 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37734993 |
| 86 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.37515209 |
| 87 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.35162971 |
| 88 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.35152427 |
| 89 | Purine metabolism_Homo sapiens_hsa00230 | 0.33397477 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.32994740 |
| 91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.32121047 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.31500674 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.30422611 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.30303364 |
| 95 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.29299127 |
| 96 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.26874825 |
| 97 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.26704948 |
| 98 | Bile secretion_Homo sapiens_hsa04976 | 0.26488445 |
| 99 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.25584722 |
| 100 | Circadian entrainment_Homo sapiens_hsa04713 | 0.21512147 |

