RPS17P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.61709129
2viral transcription (GO:0019083)8.23880390
3ribosomal small subunit biogenesis (GO:0042274)7.82899942
4translational termination (GO:0006415)7.79411654
5maturation of SSU-rRNA (GO:0030490)6.66959262
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.62580439
7cotranslational protein targeting to membrane (GO:0006613)6.56635494
8translational elongation (GO:0006414)6.48152867
9protein targeting to ER (GO:0045047)6.47223749
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.21629623
11protein localization to endoplasmic reticulum (GO:0070972)6.06878383
12cellular protein complex disassembly (GO:0043624)5.99501626
13viral life cycle (GO:0019058)5.97873695
14ATP synthesis coupled proton transport (GO:0015986)5.85386414
15energy coupled proton transport, down electrochemical gradient (GO:0015985)5.85386414
16nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.71557680
17establishment of protein localization to mitochondrial membrane (GO:0090151)5.35219559
18protein complex disassembly (GO:0043241)5.16477770
19translational initiation (GO:0006413)5.14297040
20mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.02620366
21macromolecular complex disassembly (GO:0032984)4.91355287
22behavioral response to nicotine (GO:0035095)4.65187782
23substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.60172444
24substrate-independent telencephalic tangential migration (GO:0021826)4.60172444
25epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.55037968
26protein targeting to membrane (GO:0006612)4.43597256
27chaperone-mediated protein transport (GO:0072321)4.36025045
28ribosomal large subunit biogenesis (GO:0042273)4.33417005
29pyrimidine nucleobase catabolic process (GO:0006208)4.11156964
30mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.96455472
31hypothalamus development (GO:0021854)3.93361784
32translation (GO:0006412)3.90008701
33nuclear-transcribed mRNA catabolic process (GO:0000956)3.88666131
34thalamus development (GO:0021794)3.83424450
35respiratory electron transport chain (GO:0022904)3.69055984
36mRNA catabolic process (GO:0006402)3.67002293
37electron transport chain (GO:0022900)3.64999653
38protein neddylation (GO:0045116)3.64699561
39parturition (GO:0007567)3.64378413
40cell proliferation in forebrain (GO:0021846)3.63129745
41axonemal dynein complex assembly (GO:0070286)3.57294867
42GTP biosynthetic process (GO:0006183)3.38289004
43protein complex biogenesis (GO:0070271)3.37315693
44positive regulation of T cell apoptotic process (GO:0070234)3.36718881
45ribonucleoprotein complex biogenesis (GO:0022613)3.35649113
46positive regulation of growth hormone secretion (GO:0060124)3.35615376
47spinal cord association neuron differentiation (GO:0021527)3.34976483
48RNA catabolic process (GO:0006401)3.34642296
49purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.28871374
50ATP biosynthetic process (GO:0006754)3.25897386
51mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.25793365
52mitochondrial respiratory chain complex I assembly (GO:0032981)3.25793365
53NADH dehydrogenase complex assembly (GO:0010257)3.25793365
54cellular component biogenesis (GO:0044085)3.24874584
55nucleobase catabolic process (GO:0046113)3.24172769
56purine nucleoside triphosphate biosynthetic process (GO:0009145)3.22773446
57pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.16157433
58membrane repolarization during cardiac muscle cell action potential (GO:0086013)3.13538992
59negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.05951242
60epithelial cilium movement (GO:0003351)3.05851132
61establishment of protein localization to membrane (GO:0090150)3.04534157
62nonmotile primary cilium assembly (GO:0035058)3.03762921
63cardiovascular system development (GO:0072358)3.03393135
64mitochondrial respiratory chain complex assembly (GO:0033108)3.03349251
65somite development (GO:0061053)3.01886126
66viral protein processing (GO:0019082)2.96767151
67regulation of cellular respiration (GO:0043457)2.92465805
68positive regulation of respiratory burst (GO:0060267)2.91303750
69hydrogen ion transmembrane transport (GO:1902600)2.91058150
70tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.89720384
71RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.89720384
72ribonucleoside triphosphate biosynthetic process (GO:0009201)2.85737046
73UTP biosynthetic process (GO:0006228)2.84198238
74head development (GO:0060322)2.83474789
75membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.81524377
76ovulation cycle (GO:0042698)2.79742440
77protein targeting (GO:0006605)2.79088172
78regulation of microtubule-based movement (GO:0060632)2.78457069
79membrane repolarization during action potential (GO:0086011)2.77275228
80dentate gyrus development (GO:0021542)2.76841967
81positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.71305696
82neuron fate determination (GO:0048664)2.71269172
83proton transport (GO:0015992)2.70211120
84UTP metabolic process (GO:0046051)2.69661697
85membrane repolarization (GO:0086009)2.68566920
86tongue development (GO:0043586)2.68218391
87glycerophospholipid catabolic process (GO:0046475)2.68167501
88positive regulation of potassium ion transmembrane transport (GO:1901381)2.67266774
89negative regulation of DNA-templated transcription, elongation (GO:0032785)2.66996719
90chaperone-mediated protein complex assembly (GO:0051131)2.66071706
91pyrimidine nucleotide catabolic process (GO:0006244)2.63181966
92response to pheromone (GO:0019236)2.62377759
93hydrogen transport (GO:0006818)2.61752491
94establishment of protein localization to organelle (GO:0072594)2.61123329
95pattern specification involved in kidney development (GO:0061004)2.60585330
96spliceosomal complex assembly (GO:0000245)2.60507463
97segment specification (GO:0007379)2.59746562
98body morphogenesis (GO:0010171)2.58707655
99regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.58550590
100regulation of cilium movement (GO:0003352)2.56272236

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.72829344
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.39492331
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.23850206
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.06747214
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.89523170
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.42043317
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.36835567
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.36800489
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.33039317
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.31080871
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.23652434
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.22182136
13CBX2_27304074_Chip-Seq_ESCs_Mouse2.20569507
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.15445057
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.04620363
16EZH2_27294783_Chip-Seq_ESCs_Mouse2.00964578
17REST_21632747_ChIP-Seq_MESCs_Mouse1.91202001
18SUZ12_27294783_Chip-Seq_ESCs_Mouse1.90865563
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.88854378
20BMI1_23680149_ChIP-Seq_NPCS_Mouse1.88833809
21JARID2_20075857_ChIP-Seq_MESCs_Mouse1.82330837
22IRF1_19129219_ChIP-ChIP_H3396_Human1.75153407
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.74347826
24ZNF274_21170338_ChIP-Seq_K562_Hela1.73206181
25TTF2_22483619_ChIP-Seq_HELA_Human1.73128467
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.72417108
27RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.59020009
28RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56464521
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.54363004
30TP53_22573176_ChIP-Seq_HFKS_Human1.53931154
31RNF2_27304074_Chip-Seq_NSC_Mouse1.53695805
32SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.52320488
33EZH2_18974828_ChIP-Seq_MESCs_Mouse1.52159256
34RNF2_18974828_ChIP-Seq_MESCs_Mouse1.52159256
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.49470002
36CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.47766318
37ERG_21242973_ChIP-ChIP_JURKAT_Human1.47071655
38SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.46358964
39SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.44471838
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.40037341
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39315021
42VDR_22108803_ChIP-Seq_LS180_Human1.38184824
43TP53_20018659_ChIP-ChIP_R1E_Mouse1.38037595
44GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34670302
45SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.33657939
46KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.32770898
47SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.31695524
48REST_18959480_ChIP-ChIP_MESCs_Mouse1.31335054
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.30588624
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.28035538
51XRN2_22483619_ChIP-Seq_HELA_Human1.26343199
52MYC_18940864_ChIP-ChIP_HL60_Human1.24993590
53ELK1_19687146_ChIP-ChIP_HELA_Human1.23378417
54GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.23096805
55CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.19853777
56SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.19696319
57MYC_18358816_ChIP-ChIP_MESCs_Mouse1.19495597
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17966367
59RING1B_27294783_Chip-Seq_ESCs_Mouse1.16979329
60TAF2_19829295_ChIP-Seq_ESCs_Human1.16683820
61EWS_26573619_Chip-Seq_HEK293_Human1.15726391
62MYC_19079543_ChIP-ChIP_MESCs_Mouse1.15665568
63RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15622128
64CTCF_18555785_ChIP-Seq_MESCs_Mouse1.14699204
65SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09534079
66HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.08083295
67THAP11_20581084_ChIP-Seq_MESCs_Mouse1.07648840
68SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.07444138
69GATA1_26923725_Chip-Seq_HPCs_Mouse1.07367227
70OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.03610889
71MTF2_20144788_ChIP-Seq_MESCs_Mouse1.03534865
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02335644
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02335644
74FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.01559535
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.01441837
76MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00967245
77ETV2_25802403_ChIP-Seq_MESCs_Mouse1.00094922
78GATA3_21878914_ChIP-Seq_MCF-7_Human0.99509717
79PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.99160363
80ERA_21632823_ChIP-Seq_H3396_Human0.99020889
81RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.98988939
82IKZF1_21737484_ChIP-ChIP_HCT116_Human0.98559440
83VDR_23849224_ChIP-Seq_CD4+_Human0.97265996
84NCOR_22424771_ChIP-Seq_293T_Human0.96294491
85NANOG_20526341_ChIP-Seq_ESCs_Human0.96130542
86FOXP3_21729870_ChIP-Seq_TREG_Human0.95616244
87CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.93775251
88GABP_19822575_ChIP-Seq_HepG2_Human0.92186603
89CTCF_27219007_Chip-Seq_Bcells_Human0.90841230
90SOX2_16153702_ChIP-ChIP_HESCs_Human0.89236044
91YY1_21170310_ChIP-Seq_MESCs_Mouse0.87456984
92SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86373911
93ELK1_22589737_ChIP-Seq_MCF10A_Human0.86290197
94TDRD3_21172665_ChIP-Seq_MCF-7_Human0.86213534
95FOXP1_21924763_ChIP-Seq_HESCs_Human0.85945298
96IGF1R_20145208_ChIP-Seq_DFB_Human0.84814668
97BCL6_27268052_Chip-Seq_Bcells_Human0.83515268
98TOP2B_26459242_ChIP-Seq_MCF-7_Human0.83133802
99FOXA1_27270436_Chip-Seq_PROSTATE_Human0.82368420
100FOXA1_25329375_ChIP-Seq_VCAP_Human0.82368420

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.52356351
2MP0006292_abnormal_olfactory_placode5.63529816
3MP0003787_abnormal_imprinting3.20131780
4MP0003123_paternal_imprinting3.19385685
5MP0002822_catalepsy2.78890259
6MP0003122_maternal_imprinting2.64931227
7MP0003646_muscle_fatigue2.47134840
8MP0005646_abnormal_pituitary_gland2.46619390
9MP0003880_abnormal_central_pattern2.43018410
10MP0002653_abnormal_ependyma_morphology2.42981987
11MP0004142_abnormal_muscle_tone2.38997549
12MP0002163_abnormal_gland_morphology2.31459575
13MP0008789_abnormal_olfactory_epithelium2.23161440
14MP0002837_dystrophic_cardiac_calcinosis2.15466966
15MP0000778_abnormal_nervous_system2.10158476
16MP0003136_yellow_coat_color2.00413780
17MP0003121_genomic_imprinting2.00112800
18MP0001293_anophthalmia1.97528145
19MP0000049_abnormal_middle_ear1.81646275
20MP0003315_abnormal_perineum_morphology1.80068985
21MP0002160_abnormal_reproductive_system1.77210526
22MP0005394_taste/olfaction_phenotype1.73598674
23MP0005499_abnormal_olfactory_system1.73598674
24MP0005377_hearing/vestibular/ear_phenot1.73064084
25MP0003878_abnormal_ear_physiology1.73064084
26MP0001485_abnormal_pinna_reflex1.72146961
27MP0001348_abnormal_lacrimal_gland1.67256044
28MP0010030_abnormal_orbit_morphology1.58385730
29MP0002272_abnormal_nervous_system1.54514395
30MP0002638_abnormal_pupillary_reflex1.49811976
31MP0002733_abnormal_thermal_nociception1.49234201
32MP0004885_abnormal_endolymph1.47058713
33MP0002102_abnormal_ear_morphology1.42397320
34MP0002876_abnormal_thyroid_physiology1.36244639
35MP0005379_endocrine/exocrine_gland_phen1.33731640
36MP0005423_abnormal_somatic_nervous1.32544957
37MP0000631_abnormal_neuroendocrine_gland1.31161136
38MP0001529_abnormal_vocalization1.28231811
39MP0000955_abnormal_spinal_cord1.26049624
40MP0003938_abnormal_ear_development1.25259202
41MP0005645_abnormal_hypothalamus_physiol1.23928454
42MP0005551_abnormal_eye_electrophysiolog1.22988080
43MP0004133_heterotaxia1.22911535
44MP0001970_abnormal_pain_threshold1.22417936
45MP0001968_abnormal_touch/_nociception1.21842779
46MP0006276_abnormal_autonomic_nervous1.20445109
47MP0001502_abnormal_circadian_rhythm1.18983099
48MP0005389_reproductive_system_phenotype1.18017413
49MP0008877_abnormal_DNA_methylation1.17766006
50MP0001905_abnormal_dopamine_level1.14759464
51MP0002557_abnormal_social/conspecific_i1.13845981
52MP0001986_abnormal_taste_sensitivity1.12872947
53MP0000026_abnormal_inner_ear1.12408602
54MP0002938_white_spotting1.11563026
55MP0002735_abnormal_chemical_nociception1.08897312
56MP0003937_abnormal_limbs/digits/tail_de1.08866235
57MP0002736_abnormal_nociception_after1.08423164
58MP0002184_abnormal_innervation1.06690271
59MP0003635_abnormal_synaptic_transmissio1.06380396
60MP0009745_abnormal_behavioral_response1.06182803
61MP0001984_abnormal_olfaction1.05658879
62MP0005195_abnormal_posterior_eye1.04817053
63MP0004859_abnormal_synaptic_plasticity1.04239651
64MP0002752_abnormal_somatic_nervous1.03090580
65MP0002063_abnormal_learning/memory/cond1.00917510
66MP0008872_abnormal_physiological_respon1.00876897
67MP0001286_abnormal_eye_development0.99939031
68MP0004742_abnormal_vestibular_system0.99462234
69MP0005084_abnormal_gallbladder_morpholo0.99159269
70MP0003942_abnormal_urinary_system0.98339125
71MP0002233_abnormal_nose_morphology0.98157988
72MP0002572_abnormal_emotion/affect_behav0.98148173
73MP0003011_delayed_dark_adaptation0.95592471
74MP0001440_abnormal_grooming_behavior0.91621280
75MP0005187_abnormal_penis_morphology0.91183219
76MP0009053_abnormal_anal_canal0.90177125
77MP0006072_abnormal_retinal_apoptosis0.85296373
78MP0002882_abnormal_neuron_morphology0.85049162
79MP0003186_abnormal_redox_activity0.84895623
80MP0003879_abnormal_hair_cell0.84783817
81MP0001486_abnormal_startle_reflex0.84730922
82MP0004130_abnormal_muscle_cell0.83742126
83MP0008775_abnormal_heart_ventricle0.81558020
84MP0002067_abnormal_sensory_capabilities0.80267864
85MP0009046_muscle_twitch0.79649987
86MP0001963_abnormal_hearing_physiology0.79342734
87MP0002095_abnormal_skin_pigmentation0.79320055
88MP0002152_abnormal_brain_morphology0.78916161
89MP0003755_abnormal_palate_morphology0.77073361
90MP0008995_early_reproductive_senescence0.76163686
91MP0002210_abnormal_sex_determination0.73275619
92MP0009250_abnormal_appendicular_skeleto0.72258765
93MP0002229_neurodegeneration0.70603647
94MP0000372_irregular_coat_pigmentation0.70431267
95MP0003861_abnormal_nervous_system0.69692653
96MP0002064_seizures0.69659199
97MP0002249_abnormal_larynx_morphology0.68489306
98MP0000230_abnormal_systemic_arterial0.67299782
99MP0002734_abnormal_mechanical_nocicepti0.65360684
100MP0003936_abnormal_reproductive_system0.65261417

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)7.02034615
2Abnormality of cells of the erythroid lineage (HP:0012130)4.91742293
3Aplasia/Hypoplasia of the sacrum (HP:0008517)4.14305126
4Acute necrotizing encephalopathy (HP:0006965)3.98220462
5Macrocytic anemia (HP:0001972)3.87888168
6Septo-optic dysplasia (HP:0100842)3.80227593
7Myokymia (HP:0002411)3.76558445
8Abnormality of midbrain morphology (HP:0002418)3.58174460
9Molar tooth sign on MRI (HP:0002419)3.58174460
10Abnormal mitochondria in muscle tissue (HP:0008316)3.40838372
11Acute encephalopathy (HP:0006846)3.40378810
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.35433624
13Absent/shortened dynein arms (HP:0200106)3.35433624
14Abnormal number of erythroid precursors (HP:0012131)3.29755951
15Pallor (HP:0000980)3.19188477
16Rib fusion (HP:0000902)3.09278265
17Progressive macrocephaly (HP:0004481)3.08856008
18Mitochondrial inheritance (HP:0001427)3.08418592
19Stenosis of the external auditory canal (HP:0000402)3.02308393
20Asplenia (HP:0001746)2.97961198
21Medial flaring of the eyebrow (HP:0010747)2.97481695
22Maternal diabetes (HP:0009800)2.90299507
23Aplasia/Hypoplasia of the spleen (HP:0010451)2.88574058
24Pancreatic fibrosis (HP:0100732)2.83327254
25Hepatocellular necrosis (HP:0001404)2.72852017
26Absent thumb (HP:0009777)2.72166549
27Abnormal ciliary motility (HP:0012262)2.71376581
28Abnormal respiratory motile cilium morphology (HP:0005938)2.69217417
29Abnormal respiratory epithelium morphology (HP:0012253)2.69217417
30Supernumerary spleens (HP:0009799)2.64357671
31Increased CSF lactate (HP:0002490)2.63027140
32Abnormality of DNA repair (HP:0003254)2.60820451
33Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.60640699
34Colon cancer (HP:0003003)2.48683213
35Absent rod-and cone-mediated responses on ERG (HP:0007688)2.45976324
36Partial duplication of thumb phalanx (HP:0009944)2.44277507
37Absent septum pellucidum (HP:0001331)2.43891479
38Optic nerve hypoplasia (HP:0000609)2.43554851
39Nephronophthisis (HP:0000090)2.43395455
40Gait imbalance (HP:0002141)2.43022843
41Pendular nystagmus (HP:0012043)2.40968797
42Sclerocornea (HP:0000647)2.39408494
43Hepatic necrosis (HP:0002605)2.34888232
44True hermaphroditism (HP:0010459)2.34569879
45Cerebral edema (HP:0002181)2.34051073
46Flat capital femoral epiphysis (HP:0003370)2.31079833
47Anencephaly (HP:0002323)2.30978101
48Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.30596750
49Abnormal respiratory motile cilium physiology (HP:0012261)2.29818842
50Agitation (HP:0000713)2.28760290
51Congenital primary aphakia (HP:0007707)2.28062881
52Optic disc pallor (HP:0000543)2.27540778
53Type II lissencephaly (HP:0007260)2.25584009
54Depressed nasal ridge (HP:0000457)2.23712236
55Hip dysplasia (HP:0001385)2.22300167
56Bifid tongue (HP:0010297)2.21137495
5711 pairs of ribs (HP:0000878)2.20461532
58Pancreatic cysts (HP:0001737)2.19180181
59Synostosis of carpal bones (HP:0005048)2.18987456
60Hyperthyroidism (HP:0000836)2.18124814
61Anophthalmia (HP:0000528)2.17317799
62Nephrogenic diabetes insipidus (HP:0009806)2.12913926
63Abnormal rod and cone electroretinograms (HP:0008323)2.12550937
64Growth hormone deficiency (HP:0000824)2.11738354
65Abnormality of the phalanges of the 5th finger (HP:0004213)2.11691475
66Hepatoblastoma (HP:0002884)2.08762027
67Hyperphosphatemia (HP:0002905)2.08629921
68Adrenal hypoplasia (HP:0000835)2.08468536
69Congenital stationary night blindness (HP:0007642)2.03927489
70Osteomalacia (HP:0002749)2.01637138
71Partial duplication of the phalanx of hand (HP:0009999)2.00369850
72Retinal dysplasia (HP:0007973)1.98958911
73Postaxial foot polydactyly (HP:0001830)1.91913152
74Abnormality of the renal medulla (HP:0100957)1.90100388
75Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.89680302
76Missing ribs (HP:0000921)1.89353015
77Increased hepatocellular lipid droplets (HP:0006565)1.88323465
78Duplication of thumb phalanx (HP:0009942)1.87985267
79Abnormality of renal resorption (HP:0011038)1.87066393
80Abnormality of the renal collecting system (HP:0004742)1.84122235
81Poor coordination (HP:0002370)1.83472352
82Renal Fanconi syndrome (HP:0001994)1.81845637
83Holoprosencephaly (HP:0001360)1.80600299
84Abnormal hemoglobin (HP:0011902)1.80291208
85Lipid accumulation in hepatocytes (HP:0006561)1.78753848
86Hypogonadotrophic hypogonadism (HP:0000044)1.78182102
87Neoplasm of the adrenal cortex (HP:0100641)1.77794863
88Symphalangism affecting the phalanges of the hand (HP:0009773)1.77045720
89Leukodystrophy (HP:0002415)1.75908025
90Abnormality of the labia minora (HP:0012880)1.73031534
91Increased corneal curvature (HP:0100692)1.72500411
92Keratoconus (HP:0000563)1.72500411
93Polyphagia (HP:0002591)1.69297650
94Vaginal atresia (HP:0000148)1.68669539
95Chorioretinal atrophy (HP:0000533)1.67041618
96Short femoral neck (HP:0100864)1.66937645
97Abnormality of the 4th metacarpal (HP:0010012)1.66521527
98Cystic liver disease (HP:0006706)1.66442975
99Aplasia/Hypoplasia of the tongue (HP:0010295)1.64098858
100Pachygyria (HP:0001302)1.63161124

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K124.34091956
2CDK194.02306607
3DYRK22.60814096
4WNK42.59974503
5LRRK22.43831789
6MAP3K92.42961942
7MAP4K22.39723566
8CASK2.35493236
9MAP3K42.30098445
10STK162.06343833
11MAP2K72.02479866
12LIMK11.81262329
13MAP3K111.73108507
14PINK11.70638543
15GRK11.66299496
16EPHB21.64765544
17TYRO31.64150202
18EPHA41.63452310
19MAP2K41.61086182
20ADRBK21.56924101
21TIE11.50534275
22NUAK11.42919754
23ZAK1.41986414
24ARAF1.40986614
25BCKDK1.40150936
26NTRK21.38642055
27DAPK31.37797368
28TAF11.26632902
29VRK21.23947074
30CAMK11.20660630
31DYRK1B1.11791250
32PRKCG1.10524266
33DAPK21.09316041
34CDC71.08693278
35WNK11.07833892
36MINK11.04173833
37FRK1.02045434
38CSNK1G21.01304559
39STK390.99749805
40PIK3CA0.96664428
41ADRBK10.94191430
42CSNK1G30.93100982
43PAK30.91010285
44TLK10.89497102
45WNK30.86509674
46MYLK0.85223730
47VRK10.84312137
48RPS6KA60.82768280
49ERBB30.79978781
50MAP3K60.79574842
51PRKCI0.77832343
52NME10.77080084
53CSNK1G10.76691316
54AURKA0.73107927
55AURKB0.72767532
56PRKACA0.70706446
57CSNK2A20.69962576
58MARK20.68767351
59OXSR10.68197584
60DYRK30.66843450
61PLK20.66446714
62MARK10.65408883
63CSNK1E0.62887696
64INSRR0.62417647
65RPS6KL10.61953509
66RPS6KC10.61953509
67CAMKK20.60348934
68RPS6KB20.58695588
69MAPK130.58365462
70PHKG20.57315532
71PHKG10.57315532
72PLK10.57169669
73MAP2K20.56662339
74BTK0.55922726
75UHMK10.55744069
76BRAF0.54435889
77STK110.52294718
78NME20.51025786
79TNIK0.50645304
80ILK0.49684498
81PLK30.49264871
82STK30.49192691
83PLK40.48969458
84RPS6KA20.48254923
85PRKCQ0.48024076
86CSF1R0.47767853
87GRK50.45119968
88CAMK1D0.44226699
89ROCK10.44126957
90CSNK1A1L0.43749433
91CSNK1A10.43584820
92PTK60.43379857
93CDK140.42988074
94TXK0.42854684
95OBSCN0.41110420
96PRKCE0.40438639
97FLT30.40058377
98TEC0.39778675
99DAPK10.38847197
100ABL20.38773423

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.21460222
2Oxidative phosphorylation_Homo sapiens_hsa001904.66185666
3Parkinsons disease_Homo sapiens_hsa050124.13310520
4Cardiac muscle contraction_Homo sapiens_hsa042603.22283449
5Alzheimers disease_Homo sapiens_hsa050102.86517297
6Huntingtons disease_Homo sapiens_hsa050162.84655649
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.51917048
8Linoleic acid metabolism_Homo sapiens_hsa005912.13720978
9Protein export_Homo sapiens_hsa030602.08811094
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.05083585
11Proteasome_Homo sapiens_hsa030501.98847981
12RNA polymerase_Homo sapiens_hsa030201.88098614
13Homologous recombination_Homo sapiens_hsa034401.62771901
14Asthma_Homo sapiens_hsa053101.60372848
15alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.55667290
16Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.43025805
17Nucleotide excision repair_Homo sapiens_hsa034201.36716324
18Nicotine addiction_Homo sapiens_hsa050331.35230935
19Basal transcription factors_Homo sapiens_hsa030221.35217806
20Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.32055897
21RNA degradation_Homo sapiens_hsa030181.31827645
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.26188218
23Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.19401561
24Caffeine metabolism_Homo sapiens_hsa002321.09532287
25Basal cell carcinoma_Homo sapiens_hsa052171.09046156
26Phototransduction_Homo sapiens_hsa047441.07705493
27Arachidonic acid metabolism_Homo sapiens_hsa005901.05318761
28Peroxisome_Homo sapiens_hsa041461.01653125
29Steroid biosynthesis_Homo sapiens_hsa001000.99696291
30Fanconi anemia pathway_Homo sapiens_hsa034600.96389045
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91335340
32Ether lipid metabolism_Homo sapiens_hsa005650.88219736
33Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.87622757
34Olfactory transduction_Homo sapiens_hsa047400.86469685
35Pyrimidine metabolism_Homo sapiens_hsa002400.85798239
36Tryptophan metabolism_Homo sapiens_hsa003800.85224673
37Axon guidance_Homo sapiens_hsa043600.84484673
38Butanoate metabolism_Homo sapiens_hsa006500.84057406
39Hedgehog signaling pathway_Homo sapiens_hsa043400.83240779
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.82812602
41Morphine addiction_Homo sapiens_hsa050320.81292427
42Intestinal immune network for IgA production_Homo sapiens_hsa046720.80398935
43Insulin secretion_Homo sapiens_hsa049110.79250162
44Purine metabolism_Homo sapiens_hsa002300.76616670
45RNA transport_Homo sapiens_hsa030130.75448630
46Serotonergic synapse_Homo sapiens_hsa047260.73896380
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.71342171
48Propanoate metabolism_Homo sapiens_hsa006400.70283976
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69610761
50Chemical carcinogenesis_Homo sapiens_hsa052040.68961876
51Spliceosome_Homo sapiens_hsa030400.67869863
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.66214354
53Cocaine addiction_Homo sapiens_hsa050300.63940881
54DNA replication_Homo sapiens_hsa030300.62792267
55Dopaminergic synapse_Homo sapiens_hsa047280.61105665
56Metabolic pathways_Homo sapiens_hsa011000.61097790
57Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61046279
58Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60382282
59Glutamatergic synapse_Homo sapiens_hsa047240.59576598
60Pyruvate metabolism_Homo sapiens_hsa006200.59431653
61GABAergic synapse_Homo sapiens_hsa047270.58571210
62Retinol metabolism_Homo sapiens_hsa008300.55685049
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54240831
64Ovarian steroidogenesis_Homo sapiens_hsa049130.54190007
65Collecting duct acid secretion_Homo sapiens_hsa049660.52276112
66beta-Alanine metabolism_Homo sapiens_hsa004100.51692589
67Circadian entrainment_Homo sapiens_hsa047130.48874533
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48847331
69Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48659435
70Mismatch repair_Homo sapiens_hsa034300.47939421
71Nitrogen metabolism_Homo sapiens_hsa009100.47888630
72Autoimmune thyroid disease_Homo sapiens_hsa053200.46350198
73Cholinergic synapse_Homo sapiens_hsa047250.46132603
74Notch signaling pathway_Homo sapiens_hsa043300.43104729
75Oxytocin signaling pathway_Homo sapiens_hsa049210.42700273
76Vitamin B6 metabolism_Homo sapiens_hsa007500.41172123
77Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40992091
78Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.40637325
79Melanoma_Homo sapiens_hsa052180.40358212
80Sulfur relay system_Homo sapiens_hsa041220.39486658
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.39211762
82Allograft rejection_Homo sapiens_hsa053300.38280573
83Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.36397437
84Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.35572853
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34942129
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34229881
87Fat digestion and absorption_Homo sapiens_hsa049750.33911916
88Wnt signaling pathway_Homo sapiens_hsa043100.33848573
89Long-term depression_Homo sapiens_hsa047300.33832807
90Taste transduction_Homo sapiens_hsa047420.32039330
91Ras signaling pathway_Homo sapiens_hsa040140.31754954
92Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31427408
93Synaptic vesicle cycle_Homo sapiens_hsa047210.30700631
94Hippo signaling pathway_Homo sapiens_hsa043900.29531480
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.29142513
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.29046789
97Maturity onset diabetes of the young_Homo sapiens_hsa049500.27945439
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.26696800
99Arginine and proline metabolism_Homo sapiens_hsa003300.25631037
100One carbon pool by folate_Homo sapiens_hsa006700.25218428

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