Rank | Gene Set | Z-score |
---|---|---|
1 | maturation of SSU-rRNA (GO:0030490) | 8.84368802 |
2 | ribosomal small subunit assembly (GO:0000028) | 8.75355477 |
3 | viral transcription (GO:0019083) | 8.14460725 |
4 | ribosomal small subunit biogenesis (GO:0042274) | 7.96191935 |
5 | translational termination (GO:0006415) | 7.82427825 |
6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.76311829 |
7 | cotranslational protein targeting to membrane (GO:0006613) | 6.71293160 |
8 | translational elongation (GO:0006414) | 6.70563301 |
9 | protein targeting to ER (GO:0045047) | 6.61490857 |
10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.31272098 |
11 | protein localization to endoplasmic reticulum (GO:0070972) | 6.23485796 |
12 | cellular protein complex disassembly (GO:0043624) | 5.92306436 |
13 | viral life cycle (GO:0019058) | 5.88260389 |
14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.79869373 |
15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.27065758 |
16 | ATP synthesis coupled proton transport (GO:0015986) | 5.27065758 |
17 | translational initiation (GO:0006413) | 5.09473534 |
18 | protein complex disassembly (GO:0043241) | 4.93895337 |
19 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.93221442 |
20 | macromolecular complex disassembly (GO:0032984) | 4.77768400 |
21 | ribosomal large subunit biogenesis (GO:0042273) | 4.73467848 |
22 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.63670634 |
23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.45152130 |
24 | protein targeting to membrane (GO:0006612) | 4.40698549 |
25 | chaperone-mediated protein transport (GO:0072321) | 4.35189029 |
26 | respiratory electron transport chain (GO:0022904) | 4.33751088 |
27 | electron transport chain (GO:0022900) | 4.28172577 |
28 | translation (GO:0006412) | 4.22415103 |
29 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.18768334 |
30 | DNA deamination (GO:0045006) | 4.15336376 |
31 | protein complex biogenesis (GO:0070271) | 3.95067253 |
32 | mRNA catabolic process (GO:0006402) | 3.95032209 |
33 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.94792169 |
34 | gonadal mesoderm development (GO:0007506) | 3.83871717 |
35 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.80878555 |
36 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.80878555 |
37 | base-excision repair, AP site formation (GO:0006285) | 3.76495869 |
38 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.70290550 |
39 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.70290550 |
40 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.66680060 |
41 | protein neddylation (GO:0045116) | 3.64705009 |
42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.60765996 |
43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.60765996 |
44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.60765996 |
45 | ubiquinone biosynthetic process (GO:0006744) | 3.58357923 |
46 | RNA catabolic process (GO:0006401) | 3.56979637 |
47 | nonmotile primary cilium assembly (GO:0035058) | 3.55762571 |
48 | protein-cofactor linkage (GO:0018065) | 3.53531709 |
49 | cellular component biogenesis (GO:0044085) | 3.51990267 |
50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46962381 |
51 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.45264810 |
52 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.45003773 |
53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.40972716 |
54 | behavioral response to nicotine (GO:0035095) | 3.38258609 |
55 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.35966982 |
56 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.27697827 |
57 | negative regulation of telomere maintenance (GO:0032205) | 3.27427473 |
58 | hydrogen ion transmembrane transport (GO:1902600) | 3.22481735 |
59 | ubiquinone metabolic process (GO:0006743) | 3.20805751 |
60 | ATP biosynthetic process (GO:0006754) | 3.11225575 |
61 | quinone biosynthetic process (GO:1901663) | 3.07727551 |
62 | proton transport (GO:0015992) | 3.04198228 |
63 | metallo-sulfur cluster assembly (GO:0031163) | 3.03955631 |
64 | iron-sulfur cluster assembly (GO:0016226) | 3.03955631 |
65 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.03312846 |
66 | establishment of protein localization to membrane (GO:0090150) | 3.00215774 |
67 | hydrogen transport (GO:0006818) | 2.98532291 |
68 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.96566428 |
69 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.95806002 |
70 | protein targeting (GO:0006605) | 2.89110688 |
71 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.81023998 |
72 | GTP biosynthetic process (GO:0006183) | 2.78255873 |
73 | deoxyribose phosphate catabolic process (GO:0046386) | 2.77540162 |
74 | deoxyribonucleotide catabolic process (GO:0009264) | 2.75118124 |
75 | regulation of cellular respiration (GO:0043457) | 2.73638013 |
76 | negative regulation of appetite (GO:0032099) | 2.68849199 |
77 | negative regulation of response to food (GO:0032096) | 2.68849199 |
78 | establishment of protein localization to organelle (GO:0072594) | 2.66704045 |
79 | ribonucleoprotein complex disassembly (GO:0032988) | 2.66505526 |
80 | negative regulation of mast cell activation (GO:0033004) | 2.66292744 |
81 | cell proliferation in forebrain (GO:0021846) | 2.64641961 |
82 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.61238789 |
83 | somite development (GO:0061053) | 2.60733337 |
84 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.60454373 |
85 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.60452244 |
86 | positive regulation of respiratory burst (GO:0060267) | 2.57735887 |
87 | intracellular protein transmembrane import (GO:0044743) | 2.54707056 |
88 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.54447778 |
89 | CTP metabolic process (GO:0046036) | 2.53669258 |
90 | CTP biosynthetic process (GO:0006241) | 2.53669258 |
91 | protein polyglutamylation (GO:0018095) | 2.53611525 |
92 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.53509155 |
93 | peptidyl-histidine modification (GO:0018202) | 2.53046610 |
94 | regulation of cilium movement (GO:0003352) | 2.52957565 |
95 | pseudouridine synthesis (GO:0001522) | 2.52506809 |
96 | male meiosis I (GO:0007141) | 2.51783149 |
97 | platelet dense granule organization (GO:0060155) | 2.48796676 |
98 | rRNA processing (GO:0006364) | 2.48378641 |
99 | cardiovascular system development (GO:0072358) | 2.47490433 |
100 | neuron fate determination (GO:0048664) | 2.45024407 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.58190243 |
2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.17316504 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.06960789 |
4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.48311047 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.01849744 |
6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.95970851 |
7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95814790 |
8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78169535 |
9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.73855197 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.40455697 |
11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.32456360 |
12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.29776944 |
13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.10284364 |
14 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.10110330 |
15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.02451131 |
16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.01192745 |
17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.89751315 |
18 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.89695694 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.74232107 |
20 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.67607383 |
21 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.66434577 |
22 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.63946912 |
23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.59052577 |
24 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.57420959 |
25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56604118 |
26 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.56038480 |
27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.55906998 |
28 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.52887188 |
29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.48627583 |
30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.43348797 |
31 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.41062857 |
32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.40551913 |
33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.39645947 |
34 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.38034522 |
35 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.35697209 |
36 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.35378549 |
37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.34704090 |
38 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33600312 |
39 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.32557965 |
40 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.28960565 |
41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.28831898 |
42 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.28295087 |
43 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.28137971 |
44 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.28097251 |
45 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.27790736 |
46 | AR_20517297_ChIP-Seq_VCAP_Human | 1.27739622 |
47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.26216091 |
48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.23292483 |
49 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.21464431 |
50 | NCOR_22424771_ChIP-Seq_293T_Human | 1.21031304 |
51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20621652 |
52 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.20408469 |
53 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16819729 |
54 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.15621343 |
55 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.15420766 |
56 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.13843400 |
57 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.13262501 |
58 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.13115755 |
59 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13011557 |
60 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.11950009 |
61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.11315873 |
62 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.10456871 |
63 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.08795074 |
64 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.08438904 |
65 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.05744645 |
66 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05443289 |
67 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.05021038 |
68 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04904453 |
69 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.04227805 |
70 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.03650422 |
71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03322335 |
72 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03322335 |
73 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.02211793 |
74 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01497436 |
75 | ERA_21632823_ChIP-Seq_H3396_Human | 1.00885367 |
76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98423784 |
77 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.98245963 |
78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.98208254 |
79 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98199474 |
80 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.97599619 |
81 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.96620418 |
82 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95911389 |
83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.95740835 |
84 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.94466436 |
85 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.94281996 |
86 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.93028272 |
87 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.92165044 |
88 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.91387520 |
89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.90729620 |
90 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89726960 |
91 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.89007165 |
92 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.87670832 |
93 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.87615930 |
94 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.85370667 |
95 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.85065709 |
96 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85004667 |
97 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.84008715 |
98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.83369686 |
99 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.82093975 |
100 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.80796335 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 6.14592395 |
2 | MP0006292_abnormal_olfactory_placode | 3.67302881 |
3 | MP0002653_abnormal_ependyma_morphology | 2.93316343 |
4 | MP0002163_abnormal_gland_morphology | 2.90867445 |
5 | MP0008877_abnormal_DNA_methylation | 2.88838987 |
6 | MP0005645_abnormal_hypothalamus_physiol | 2.44964761 |
7 | MP0002160_abnormal_reproductive_system | 2.34602405 |
8 | MP0005646_abnormal_pituitary_gland | 2.21192130 |
9 | MP0003122_maternal_imprinting | 2.19735269 |
10 | MP0004142_abnormal_muscle_tone | 2.17906096 |
11 | MP0004147_increased_porphyrin_level | 2.04503985 |
12 | MP0005389_reproductive_system_phenotype | 2.00056903 |
13 | MP0003787_abnormal_imprinting | 1.99596331 |
14 | MP0008789_abnormal_olfactory_epithelium | 1.96525027 |
15 | MP0004885_abnormal_endolymph | 1.95577429 |
16 | MP0005379_endocrine/exocrine_gland_phen | 1.93615328 |
17 | MP0006072_abnormal_retinal_apoptosis | 1.88946293 |
18 | MP0006276_abnormal_autonomic_nervous | 1.85445164 |
19 | MP0002234_abnormal_pharynx_morphology | 1.78572129 |
20 | MP0005671_abnormal_response_to | 1.77524418 |
21 | MP0008995_early_reproductive_senescence | 1.71477569 |
22 | MP0002876_abnormal_thyroid_physiology | 1.67762814 |
23 | MP0001919_abnormal_reproductive_system | 1.62448432 |
24 | MP0003646_muscle_fatigue | 1.61613175 |
25 | MP0005377_hearing/vestibular/ear_phenot | 1.61490689 |
26 | MP0003878_abnormal_ear_physiology | 1.61490689 |
27 | MP0005551_abnormal_eye_electrophysiolog | 1.56200622 |
28 | MP0002837_dystrophic_cardiac_calcinosis | 1.55184072 |
29 | MP0001293_anophthalmia | 1.50749591 |
30 | MP0001905_abnormal_dopamine_level | 1.47289787 |
31 | MP0003121_genomic_imprinting | 1.45112839 |
32 | MP0008872_abnormal_physiological_respon | 1.44901431 |
33 | MP0005394_taste/olfaction_phenotype | 1.40982932 |
34 | MP0005499_abnormal_olfactory_system | 1.40982932 |
35 | MP0000631_abnormal_neuroendocrine_gland | 1.38764807 |
36 | MP0000516_abnormal_urinary_system | 1.38011917 |
37 | MP0005367_renal/urinary_system_phenotyp | 1.38011917 |
38 | MP0004145_abnormal_muscle_electrophysio | 1.34000839 |
39 | MP0001485_abnormal_pinna_reflex | 1.31935817 |
40 | MP0003136_yellow_coat_color | 1.27938973 |
41 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25980581 |
42 | MP0000049_abnormal_middle_ear | 1.21626832 |
43 | MP0002736_abnormal_nociception_after | 1.20411730 |
44 | MP0001986_abnormal_taste_sensitivity | 1.18301571 |
45 | MP0003186_abnormal_redox_activity | 1.17149458 |
46 | MP0009745_abnormal_behavioral_response | 1.15368406 |
47 | MP0003786_premature_aging | 1.13557989 |
48 | MP0003315_abnormal_perineum_morphology | 1.11109617 |
49 | MP0000372_irregular_coat_pigmentation | 1.10679913 |
50 | MP0005670_abnormal_white_adipose | 1.10604372 |
51 | MP0000778_abnormal_nervous_system | 1.10537821 |
52 | MP0003880_abnormal_central_pattern | 1.10471078 |
53 | MP0004133_heterotaxia | 1.10238400 |
54 | MP0003195_calcinosis | 1.10098692 |
55 | MP0002095_abnormal_skin_pigmentation | 1.10001950 |
56 | MP0000427_abnormal_hair_cycle | 1.09293976 |
57 | MP0001968_abnormal_touch/_nociception | 1.06398605 |
58 | MP0008775_abnormal_heart_ventricle | 1.05207152 |
59 | MP0005195_abnormal_posterior_eye | 1.03999766 |
60 | MP0001440_abnormal_grooming_behavior | 1.02653702 |
61 | MP0001348_abnormal_lacrimal_gland | 1.01751464 |
62 | MP0002733_abnormal_thermal_nociception | 1.01040462 |
63 | MP0006036_abnormal_mitochondrial_physio | 1.00548994 |
64 | MP0002272_abnormal_nervous_system | 0.97975729 |
65 | MP0003942_abnormal_urinary_system | 0.95212734 |
66 | MP0009764_decreased_sensitivity_to | 0.94128088 |
67 | MP0004043_abnormal_pH_regulation | 0.94028375 |
68 | MP0001970_abnormal_pain_threshold | 0.91531328 |
69 | MP0002928_abnormal_bile_duct | 0.91446161 |
70 | MP0005423_abnormal_somatic_nervous | 0.91006331 |
71 | MP0003879_abnormal_hair_cell | 0.89513353 |
72 | MP0001529_abnormal_vocalization | 0.88495119 |
73 | MP0000026_abnormal_inner_ear | 0.88376290 |
74 | MP0002184_abnormal_innervation | 0.87889043 |
75 | MP0002102_abnormal_ear_morphology | 0.87716511 |
76 | MP0001486_abnormal_startle_reflex | 0.85253190 |
77 | MP0001963_abnormal_hearing_physiology | 0.85193019 |
78 | MP0006035_abnormal_mitochondrial_morpho | 0.84217471 |
79 | MP0001727_abnormal_embryo_implantation | 0.83268831 |
80 | MP0003806_abnormal_nucleotide_metabolis | 0.82705368 |
81 | MP0002210_abnormal_sex_determination | 0.82508046 |
82 | MP0003123_paternal_imprinting | 0.82224413 |
83 | MP0005253_abnormal_eye_physiology | 0.82121632 |
84 | MP0002752_abnormal_somatic_nervous | 0.80629772 |
85 | MP0005636_abnormal_mineral_homeostasis | 0.79863778 |
86 | MP0000955_abnormal_spinal_cord | 0.79857321 |
87 | MP0000613_abnormal_salivary_gland | 0.79776840 |
88 | MP0009046_muscle_twitch | 0.79350195 |
89 | MP0001984_abnormal_olfaction | 0.78458205 |
90 | MP0005360_urolithiasis | 0.76647872 |
91 | MP0002277_abnormal_respiratory_mucosa | 0.76260707 |
92 | MP0002938_white_spotting | 0.74226947 |
93 | MP0000230_abnormal_systemic_arterial | 0.70726277 |
94 | MP0002557_abnormal_social/conspecific_i | 0.70251278 |
95 | MP0001145_abnormal_male_reproductive | 0.69887387 |
96 | MP0004742_abnormal_vestibular_system | 0.68546426 |
97 | MP0002132_abnormal_respiratory_system | 0.68040152 |
98 | MP0001765_abnormal_ion_homeostasis | 0.67776006 |
99 | MP0005084_abnormal_gallbladder_morpholo | 0.67328301 |
100 | MP0004019_abnormal_vitamin_homeostasis | 0.65980456 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Reticulocytopenia (HP:0001896) | 6.49896157 |
2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.96809718 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 4.89323735 |
4 | Macrocytic anemia (HP:0001972) | 3.93359887 |
5 | 3-Methylglutaconic aciduria (HP:0003535) | 3.77249146 |
6 | Abnormality of B cell number (HP:0010975) | 3.77041281 |
7 | Molar tooth sign on MRI (HP:0002419) | 3.69305255 |
8 | Abnormality of midbrain morphology (HP:0002418) | 3.69305255 |
9 | Acute necrotizing encephalopathy (HP:0006965) | 3.59918568 |
10 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.45781625 |
11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.36113398 |
12 | Mitochondrial inheritance (HP:0001427) | 3.35413927 |
13 | Pancreatic fibrosis (HP:0100732) | 3.33973721 |
14 | Congenital stationary night blindness (HP:0007642) | 3.19961548 |
15 | Pallor (HP:0000980) | 3.14741456 |
16 | Acute encephalopathy (HP:0006846) | 3.13963418 |
17 | Absent thumb (HP:0009777) | 3.11249982 |
18 | True hermaphroditism (HP:0010459) | 3.07789980 |
19 | Septo-optic dysplasia (HP:0100842) | 3.06134309 |
20 | Increased CSF lactate (HP:0002490) | 2.95875671 |
21 | Hepatocellular necrosis (HP:0001404) | 2.92855484 |
22 | Hepatic necrosis (HP:0002605) | 2.90190724 |
23 | Pancreatic cysts (HP:0001737) | 2.88583409 |
24 | Progressive macrocephaly (HP:0004481) | 2.88209437 |
25 | Colon cancer (HP:0003003) | 2.86149975 |
26 | Medial flaring of the eyebrow (HP:0010747) | 2.85431348 |
27 | B lymphocytopenia (HP:0010976) | 2.81177007 |
28 | Nephronophthisis (HP:0000090) | 2.79748342 |
29 | Stenosis of the external auditory canal (HP:0000402) | 2.79320835 |
30 | Type II lissencephaly (HP:0007260) | 2.76375441 |
31 | Panhypogammaglobulinemia (HP:0003139) | 2.75803785 |
32 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.71578882 |
33 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.65455904 |
34 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.63840215 |
35 | Severe combined immunodeficiency (HP:0004430) | 2.63797527 |
36 | Myokymia (HP:0002411) | 2.62773509 |
37 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.59343346 |
38 | Asplenia (HP:0001746) | 2.56545071 |
39 | Pendular nystagmus (HP:0012043) | 2.55174863 |
40 | Abolished electroretinogram (ERG) (HP:0000550) | 2.47648079 |
41 | Thyroiditis (HP:0100646) | 2.46799997 |
42 | Sclerocornea (HP:0000647) | 2.35461064 |
43 | IgG deficiency (HP:0004315) | 2.34827709 |
44 | Abnormality of the renal medulla (HP:0100957) | 2.33460064 |
45 | Abnormality of DNA repair (HP:0003254) | 2.28576889 |
46 | Gait imbalance (HP:0002141) | 2.27730320 |
47 | Postaxial foot polydactyly (HP:0001830) | 2.26181797 |
48 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.24357068 |
49 | Absent/shortened dynein arms (HP:0200106) | 2.24357068 |
50 | Hypoplasia of the thymus (HP:0000778) | 2.21626684 |
51 | Renal cortical cysts (HP:0000803) | 2.19368056 |
52 | Abnormality of the renal cortex (HP:0011035) | 2.18690693 |
53 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.18604298 |
54 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.18604298 |
55 | Male pseudohermaphroditism (HP:0000037) | 2.18252821 |
56 | Congenital primary aphakia (HP:0007707) | 2.17975163 |
57 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.14211229 |
58 | Increased serum lactate (HP:0002151) | 2.13380252 |
59 | Cerebral edema (HP:0002181) | 2.11319869 |
60 | Stomach cancer (HP:0012126) | 2.10873399 |
61 | Increased IgM level (HP:0003496) | 2.10365816 |
62 | Erythroderma (HP:0001019) | 2.07129136 |
63 | Optic disc pallor (HP:0000543) | 2.05832585 |
64 | Hypoproteinemia (HP:0003075) | 2.05622589 |
65 | Abnormality of reticulocytes (HP:0004312) | 2.05133612 |
66 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.03824655 |
67 | Lactic acidosis (HP:0003128) | 2.02737894 |
68 | Absent septum pellucidum (HP:0001331) | 2.02630958 |
69 | Optic nerve hypoplasia (HP:0000609) | 2.01757672 |
70 | Delayed CNS myelination (HP:0002188) | 2.01648888 |
71 | Abnormal ciliary motility (HP:0012262) | 2.00510838 |
72 | Nephrogenic diabetes insipidus (HP:0009806) | 2.00466352 |
73 | Cystic liver disease (HP:0006706) | 1.95093665 |
74 | Rib fusion (HP:0000902) | 1.94603722 |
75 | Eosinophilia (HP:0001880) | 1.94335558 |
76 | Combined immunodeficiency (HP:0005387) | 1.93801889 |
77 | Generalized aminoaciduria (HP:0002909) | 1.90716010 |
78 | Respiratory failure (HP:0002878) | 1.90520235 |
79 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.88551032 |
80 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.88551032 |
81 | Type 2 muscle fiber atrophy (HP:0003554) | 1.88063887 |
82 | Depressed nasal ridge (HP:0000457) | 1.86758529 |
83 | Abnormality of T cell number (HP:0011839) | 1.81487370 |
84 | Hypoplasia of the radius (HP:0002984) | 1.81331514 |
85 | Increased intramyocellular lipid droplets (HP:0012240) | 1.80165071 |
86 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.79283132 |
87 | Abnormal hemoglobin (HP:0011902) | 1.78969650 |
88 | Agitation (HP:0000713) | 1.75742705 |
89 | Abnormality of eosinophils (HP:0001879) | 1.75265970 |
90 | Anencephaly (HP:0002323) | 1.74799328 |
91 | Horseshoe kidney (HP:0000085) | 1.73506657 |
92 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.73221493 |
93 | Muscle fiber atrophy (HP:0100295) | 1.71464901 |
94 | Lipid accumulation in hepatocytes (HP:0006561) | 1.71025468 |
95 | Increased hepatocellular lipid droplets (HP:0006565) | 1.70761923 |
96 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.69005097 |
97 | Abnormality of T cells (HP:0002843) | 1.66834553 |
98 | Genital tract atresia (HP:0001827) | 1.66723996 |
99 | Lethargy (HP:0001254) | 1.65646659 |
100 | Vaginal atresia (HP:0000148) | 1.65483140 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK4 | 3.58442327 |
2 | CDK19 | 3.52005384 |
3 | MAP4K2 | 3.15549489 |
4 | TXK | 2.95568037 |
5 | ZAK | 2.92914429 |
6 | PINK1 | 2.83942381 |
7 | STK16 | 2.46441851 |
8 | TESK2 | 2.43405750 |
9 | GRK1 | 2.32253373 |
10 | ADRBK2 | 2.21731047 |
11 | FRK | 2.09893136 |
12 | STK39 | 2.07255980 |
13 | CAMKK2 | 2.02004677 |
14 | TIE1 | 1.95799763 |
15 | MUSK | 1.90285755 |
16 | TLK1 | 1.82180628 |
17 | NME2 | 1.58668991 |
18 | DYRK2 | 1.57061261 |
19 | VRK2 | 1.49472904 |
20 | PASK | 1.41527664 |
21 | PIK3CA | 1.40500562 |
22 | PIM2 | 1.37379751 |
23 | KDR | 1.34356372 |
24 | BCKDK | 1.26908188 |
25 | PLK4 | 1.20344075 |
26 | NUAK1 | 1.11272898 |
27 | NME1 | 1.08512627 |
28 | CAMKK1 | 1.07887349 |
29 | BMPR1B | 1.06992504 |
30 | ARAF | 1.06309016 |
31 | LRRK2 | 1.05272639 |
32 | LIMK1 | 1.03164286 |
33 | ABL2 | 1.03155267 |
34 | EPHB2 | 1.02493099 |
35 | INSRR | 0.95650247 |
36 | PLK2 | 0.94278557 |
37 | PRKD3 | 0.93721489 |
38 | CAMK1 | 0.93642705 |
39 | MOS | 0.91758184 |
40 | MAPK13 | 0.87681217 |
41 | CDK8 | 0.85126806 |
42 | RPS6KA6 | 0.83689166 |
43 | PRKCQ | 0.83300015 |
44 | AURKA | 0.82264788 |
45 | PAK3 | 0.81718176 |
46 | IKBKB | 0.78758693 |
47 | MAP3K12 | 0.75665140 |
48 | PRKCG | 0.74950914 |
49 | PHKG1 | 0.74783270 |
50 | PHKG2 | 0.74783270 |
51 | RPS6KC1 | 0.70991244 |
52 | RPS6KL1 | 0.70991244 |
53 | MAP3K9 | 0.69240617 |
54 | MYLK | 0.67137201 |
55 | OXSR1 | 0.66928504 |
56 | BUB1 | 0.66658274 |
57 | DAPK3 | 0.66490462 |
58 | PRKCH | 0.64322788 |
59 | RPS6KA5 | 0.62617556 |
60 | FES | 0.62236130 |
61 | PRKACA | 0.62148003 |
62 | CSNK2A2 | 0.61207945 |
63 | MAP3K4 | 0.60028767 |
64 | BRAF | 0.59349287 |
65 | ATR | 0.58966227 |
66 | ILK | 0.58738897 |
67 | NTRK3 | 0.56800068 |
68 | CHEK2 | 0.55999497 |
69 | CSNK1G3 | 0.55751900 |
70 | RPS6KA4 | 0.55441546 |
71 | IRAK4 | 0.55249530 |
72 | CSNK1G2 | 0.54961377 |
73 | VRK1 | 0.54689938 |
74 | CSNK2A1 | 0.54683053 |
75 | ADRBK1 | 0.54600397 |
76 | MATK | 0.54042028 |
77 | WNK1 | 0.53333855 |
78 | NTRK2 | 0.53276542 |
79 | SRPK1 | 0.53114674 |
80 | PRKCI | 0.53101562 |
81 | AURKB | 0.52904906 |
82 | PIM1 | 0.51162871 |
83 | GRK7 | 0.50489892 |
84 | CSNK1A1 | 0.50357637 |
85 | TYRO3 | 0.47800215 |
86 | MAP2K2 | 0.47280201 |
87 | PLK1 | 0.47054997 |
88 | PAK6 | 0.46784352 |
89 | ERBB2 | 0.46543496 |
90 | LYN | 0.46270970 |
91 | DAPK2 | 0.46076648 |
92 | CDK3 | 0.45582055 |
93 | RPS6KA2 | 0.44617099 |
94 | PRKCA | 0.43177827 |
95 | CDC7 | 0.42712044 |
96 | CDK11A | 0.42337661 |
97 | OBSCN | 0.42083870 |
98 | CSNK1E | 0.41290848 |
99 | NEK1 | 0.41055752 |
100 | PRKCD | 0.40557264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 6.67999310 |
2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.62879328 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.66268559 |
4 | Alzheimers disease_Homo sapiens_hsa05010 | 2.77879210 |
5 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.72171379 |
6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.69987192 |
7 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.58948451 |
8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.53610258 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.16946387 |
10 | Protein export_Homo sapiens_hsa03060 | 2.12605851 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 2.06338007 |
12 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.95574234 |
13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.89425086 |
14 | RNA polymerase_Homo sapiens_hsa03020 | 1.78330339 |
15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.70128401 |
16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.66915932 |
17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.61119435 |
18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.53437926 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.53247839 |
20 | Asthma_Homo sapiens_hsa05310 | 1.31760736 |
21 | Phototransduction_Homo sapiens_hsa04744 | 1.30283457 |
22 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.24325624 |
23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.24189858 |
24 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.22688097 |
25 | Sulfur relay system_Homo sapiens_hsa04122 | 1.15022337 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.13732752 |
27 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.13375494 |
28 | Allograft rejection_Homo sapiens_hsa05330 | 1.13354541 |
29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.09158915 |
30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.08360814 |
31 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.06460853 |
32 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.04691115 |
33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.04514136 |
34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.02237850 |
35 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.00743578 |
36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.96586986 |
37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.91621232 |
38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89685736 |
39 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.86899718 |
40 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.86446056 |
41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.85831645 |
42 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85814996 |
43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84702191 |
44 | Nicotine addiction_Homo sapiens_hsa05033 | 0.83976936 |
45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.83285777 |
46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.81399606 |
47 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.79729272 |
48 | Basal transcription factors_Homo sapiens_hsa03022 | 0.79486797 |
49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.76467445 |
50 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.76248581 |
51 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75657364 |
52 | Peroxisome_Homo sapiens_hsa04146 | 0.75108636 |
53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.74315901 |
54 | Mismatch repair_Homo sapiens_hsa03430 | 0.74190922 |
55 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.73684477 |
56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72734444 |
57 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.72597966 |
58 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.72089589 |
59 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71992401 |
60 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.71901053 |
61 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70590639 |
62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.69379717 |
63 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.69067714 |
64 | Spliceosome_Homo sapiens_hsa03040 | 0.68656018 |
65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68156792 |
66 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68063409 |
67 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.64797691 |
68 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.63235677 |
69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.62676853 |
70 | Base excision repair_Homo sapiens_hsa03410 | 0.60275890 |
71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.59955653 |
72 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.56823402 |
73 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.54864820 |
74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.54138129 |
75 | Morphine addiction_Homo sapiens_hsa05032 | 0.53136774 |
76 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48716908 |
77 | RNA transport_Homo sapiens_hsa03013 | 0.47507364 |
78 | DNA replication_Homo sapiens_hsa03030 | 0.47350611 |
79 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.43856652 |
80 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.43662856 |
81 | Purine metabolism_Homo sapiens_hsa00230 | 0.42576064 |
82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.39198172 |
83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36795184 |
84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35451961 |
85 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.34830807 |
86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.33609400 |
87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.32822104 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32649700 |
89 | GABAergic synapse_Homo sapiens_hsa04727 | 0.28753437 |
90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.27955262 |
91 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.25977207 |
92 | Salivary secretion_Homo sapiens_hsa04970 | 0.23507728 |
93 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.22617106 |
94 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.22309802 |
95 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.22081396 |
96 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.22030674 |
97 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.21520263 |
98 | Taste transduction_Homo sapiens_hsa04742 | 0.21450517 |
99 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.20153458 |
100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.19745938 |