RPS19BP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.73958080
2ribosomal small subunit assembly (GO:0000028)5.33819888
3chaperone-mediated protein transport (GO:0072321)5.27330159
4maturation of SSU-rRNA (GO:0030490)5.19478000
5viral transcription (GO:0019083)4.93106698
6protein maturation by protein folding (GO:0022417)4.87930277
7translational termination (GO:0006415)4.86739606
8proteasome assembly (GO:0043248)4.83351477
9ribosomal small subunit biogenesis (GO:0042274)4.79434374
10formation of translation preinitiation complex (GO:0001731)4.50968004
11negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)4.49420137
12ribosomal large subunit biogenesis (GO:0042273)4.45364752
13DNA strand elongation involved in DNA replication (GO:0006271)4.44527571
14translational elongation (GO:0006414)4.41794108
15GDP-mannose metabolic process (GO:0019673)4.39445467
16mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.39056015
17protein targeting to mitochondrion (GO:0006626)4.38369759
18ribonucleoprotein complex biogenesis (GO:0022613)4.37113398
19translational initiation (GO:0006413)4.37060525
20telomere maintenance via semi-conservative replication (GO:0032201)4.26898520
21SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.26226579
22ribosome biogenesis (GO:0042254)4.25558991
23purine nucleobase biosynthetic process (GO:0009113)4.23916542
24nucleobase biosynthetic process (GO:0046112)4.22840215
25DNA strand elongation (GO:0022616)4.21259248
26DNA replication checkpoint (GO:0000076)4.16213571
27cotranslational protein targeting to membrane (GO:0006613)4.15053005
28protein targeting to ER (GO:0045047)4.13907099
29DNA replication initiation (GO:0006270)4.13052331
30ATP synthesis coupled proton transport (GO:0015986)4.11494934
31energy coupled proton transport, down electrochemical gradient (GO:0015985)4.11494934
32negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.06318282
33spliceosomal snRNP assembly (GO:0000387)4.03360981
34ribosome assembly (GO:0042255)4.01161029
35termination of RNA polymerase III transcription (GO:0006386)3.99142280
36transcription elongation from RNA polymerase III promoter (GO:0006385)3.99142280
37rRNA modification (GO:0000154)3.95522919
38protein localization to endoplasmic reticulum (GO:0070972)3.95479644
39nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.95005854
40iron-sulfur cluster assembly (GO:0016226)3.93777011
41metallo-sulfur cluster assembly (GO:0031163)3.93777011
42rRNA processing (GO:0006364)3.93492319
43respiratory electron transport chain (GO:0022904)3.93388992
44establishment of protein localization to endoplasmic reticulum (GO:0072599)3.90587895
45deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.86295931
46pseudouridine synthesis (GO:0001522)3.85242530
47anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.84733579
48electron transport chain (GO:0022900)3.84102827
49regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.84081964
50translation (GO:0006412)3.83779696
51positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.83282236
52viral life cycle (GO:0019058)3.83193693
53cellular protein complex disassembly (GO:0043624)3.82660705
54protein localization to mitochondrion (GO:0070585)3.80325169
55rRNA metabolic process (GO:0016072)3.78664777
56GTP biosynthetic process (GO:0006183)3.78126314
57mitotic metaphase plate congression (GO:0007080)3.76403240
58telomere maintenance via recombination (GO:0000722)3.72884171
59base-excision repair, AP site formation (GO:0006285)3.72119897
60negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.69372541
61negative regulation of ligase activity (GO:0051352)3.69372541
627-methylguanosine mRNA capping (GO:0006370)3.67367939
63guanosine-containing compound biosynthetic process (GO:1901070)3.62947043
647-methylguanosine RNA capping (GO:0009452)3.60709894
65RNA capping (GO:0036260)3.60709894
66UTP biosynthetic process (GO:0006228)3.56923163
67mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.56824495
68CENP-A containing nucleosome assembly (GO:0034080)3.55683752
69cellular component biogenesis (GO:0044085)3.51556195
70transcription-coupled nucleotide-excision repair (GO:0006283)3.51532927
71negative regulation of release of cytochrome c from mitochondria (GO:0090201)3.48503327
72chromatin remodeling at centromere (GO:0031055)3.47721110
73pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.47489611
74DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.46422267
75regulation of cellular amino acid metabolic process (GO:0006521)3.44253979
76L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.43442676
77regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.43357545
78positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.43098128
79protein complex disassembly (GO:0043241)3.43011636
80telomere maintenance via telomere lengthening (GO:0010833)3.41234657
81intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.40150452
82signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.40150452
83signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.39906107
84signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.39906107
85signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.39906107
86protein neddylation (GO:0045116)3.39739519
87transcription from RNA polymerase I promoter (GO:0006360)3.38752260
88deoxyribonucleotide catabolic process (GO:0009264)3.37585684
89pyrimidine nucleotide catabolic process (GO:0006244)3.37105592
90exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.36766795
91pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.35026489
92mitotic recombination (GO:0006312)3.34588397
93signal transduction involved in DNA integrity checkpoint (GO:0072401)3.33318617
94signal transduction involved in DNA damage checkpoint (GO:0072422)3.33318617
95deoxyribose phosphate biosynthetic process (GO:0046385)3.31759532
962-deoxyribonucleotide biosynthetic process (GO:0009265)3.31759532
97protein complex biogenesis (GO:0070271)3.31339639
98positive regulation of ligase activity (GO:0051351)3.30531703
99termination of RNA polymerase I transcription (GO:0006363)3.30064953
100macromolecular complex disassembly (GO:0032984)3.29961102
101transcription elongation from RNA polymerase I promoter (GO:0006362)3.29012685
102pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.27810566
103signal transduction involved in cell cycle checkpoint (GO:0072395)3.27266635
104nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.22743089
105CTP metabolic process (GO:0046036)3.22332107
106CTP biosynthetic process (GO:0006241)3.22332107
107mitochondrial respiratory chain complex assembly (GO:0033108)3.21759581
108viral mRNA export from host cell nucleus (GO:0046784)3.20351742
109UTP metabolic process (GO:0046051)3.20339798
110deoxyribose phosphate catabolic process (GO:0046386)3.20228666
111antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.19390018
112spliceosomal complex assembly (GO:0000245)3.19219271
113purine deoxyribonucleotide catabolic process (GO:0009155)3.18755141
114G1/S transition of mitotic cell cycle (GO:0000082)3.18097660
115cell cycle G1/S phase transition (GO:0044843)3.18097660
116mitochondrial respiratory chain complex I assembly (GO:0032981)3.18052075
117NADH dehydrogenase complex assembly (GO:0010257)3.18052075
118mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.18052075
119inner mitochondrial membrane organization (GO:0007007)3.17851013
120nucleobase-containing small molecule interconversion (GO:0015949)3.16099459
121kinetochore assembly (GO:0051382)3.15232999
122establishment of integrated proviral latency (GO:0075713)3.14660015
123nuclear-transcribed mRNA catabolic process (GO:0000956)3.14472858
124folic acid metabolic process (GO:0046655)3.14032238
125mitochondrial transport (GO:0006839)3.14023792
126nucleotide-excision repair, DNA gap filling (GO:0006297)3.11545998
127DNA replication-independent nucleosome organization (GO:0034724)3.10202600
128DNA replication-independent nucleosome assembly (GO:0006336)3.10202600
129pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.10118399
130regulation of mitochondrial translation (GO:0070129)3.09726188
131oxidative phosphorylation (GO:0006119)3.09106039
132transcription from mitochondrial promoter (GO:0006390)3.08741632
133metaphase plate congression (GO:0051310)3.08731941
134regulation of ubiquitin-protein transferase activity (GO:0051438)3.08182682
135maturation of 5.8S rRNA (GO:0000460)3.07025787
136establishment of protein localization to mitochondrial membrane (GO:0090151)3.05746898
137folic acid-containing compound biosynthetic process (GO:0009396)3.05388198
138rRNA methylation (GO:0031167)3.04172213
139cytochrome complex assembly (GO:0017004)3.03073797
140DNA unwinding involved in DNA replication (GO:0006268)3.02844101
141respiratory chain complex IV assembly (GO:0008535)3.02329672
142protein deneddylation (GO:0000338)3.02319849
143establishment of protein localization to mitochondrion (GO:0072655)2.99393692
144regulation of ligase activity (GO:0051340)2.99160031
145pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.98313841
146polyamine biosynthetic process (GO:0006596)2.94206648
147regulation of mitochondrial membrane potential (GO:0051881)2.91235148
148pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.85625644
149regulation of release of cytochrome c from mitochondria (GO:0090199)2.85523127
150mitochondrial calcium ion transport (GO:0006851)2.83536010
151antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.83123838
152cullin deneddylation (GO:0010388)2.81883776
1532-deoxyribonucleotide metabolic process (GO:0009394)2.81241825
154purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.77762919
155proline biosynthetic process (GO:0006561)2.77208827
156purine nucleoside triphosphate biosynthetic process (GO:0009145)2.74887869
157peptidyl-histidine modification (GO:0018202)2.74188439

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.14231473
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.62798999
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.07884272
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.71625824
5* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.55145276
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.52874898
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.39106368
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.32336257
9MYC_18358816_ChIP-ChIP_MESCs_Mouse3.23745340
10MYC_19079543_ChIP-ChIP_MESCs_Mouse3.08141405
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.07755411
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.98182778
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.82827606
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.77214028
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.76649925
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.67145969
17XRN2_22483619_ChIP-Seq_HELA_Human2.56482265
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.54206953
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.46996936
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.40698714
21* VDR_23849224_ChIP-Seq_CD4+_Human2.39785480
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.38025673
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.36033803
24PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.32674926
25DCP1A_22483619_ChIP-Seq_HELA_Human2.31572320
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.26955077
27* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.17552591
28* GABP_19822575_ChIP-Seq_HepG2_Human2.15321028
29ELF1_17652178_ChIP-ChIP_JURKAT_Human2.11196122
30VDR_21846776_ChIP-Seq_THP-1_Human2.10827884
31FOXP3_21729870_ChIP-Seq_TREG_Human2.08561013
32* THAP11_20581084_ChIP-Seq_MESCs_Mouse2.05706357
33TTF2_22483619_ChIP-Seq_HELA_Human2.00359352
34YY1_21170310_ChIP-Seq_MESCs_Mouse2.00110167
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.98581418
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85724902
37* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.84169001
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79793161
39* TET1_21451524_ChIP-Seq_MESCs_Mouse1.76733367
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.75543279
41SRF_21415370_ChIP-Seq_HL-1_Mouse1.74911242
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74379183
43MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.74297580
44* LXR_22292898_ChIP-Seq_THP-1_Human1.72478315
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.67944713
46POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66907082
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63318578
48ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62508654
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.62031418
50AR_21909140_ChIP-Seq_LNCAP_Human1.59031847
51ELK1_19687146_ChIP-ChIP_HELA_Human1.57339610
52TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.55969040
53FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.53944810
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.51678389
55E2F1_21310950_ChIP-Seq_MCF-7_Human1.49225885
56CIITA_25753668_ChIP-Seq_RAJI_Human1.48332129
57P68_20966046_ChIP-Seq_HELA_Human1.47712038
58* ELF1_20517297_ChIP-Seq_JURKAT_Human1.43361983
59YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42776693
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.40433786
61HOXB4_20404135_ChIP-ChIP_EML_Mouse1.38906164
62CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.37964672
63BCL6_27268052_Chip-Seq_Bcells_Human1.37172187
64KDM5A_27292631_Chip-Seq_BREAST_Human1.36542486
65PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.35919518
66SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35860753
67* ELK3_25401928_ChIP-Seq_HUVEC_Human1.35760662
68* BCOR_27268052_Chip-Seq_Bcells_Human1.31489932
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.30550459
70* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29947557
71* CTCF_26484167_Chip-Seq_Bcells_Mouse1.29858186
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.29211775
73ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.28483694
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.28192379
75RARG_19884340_ChIP-ChIP_MEFs_Mouse1.26718131
76POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26512773
77* FOXP1_21924763_ChIP-Seq_HESCs_Human1.25857471
78RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.24243989
79BP1_19119308_ChIP-ChIP_Hs578T_Human1.24217996
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.23842774
81KLF4_18555785_ChIP-Seq_MESCs_Mouse1.21570999
82* ELK1_22589737_ChIP-Seq_MCF10A_Human1.21568605
83DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21557289
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20749922
85MAF_26560356_Chip-Seq_TH2_Human1.19578317
86SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.17831515
87CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.17371992
88SA1_27219007_Chip-Seq_ERYTHROID_Human1.15839047
89* MYC_22102868_ChIP-Seq_BL_Human1.13812925
90MYC_18940864_ChIP-ChIP_HL60_Human1.11112070
91BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11050583
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.10889900
93* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.10841882
94YY1_22570637_ChIP-Seq_MALME-3M_Human1.10618150
95* PHF8_20622854_ChIP-Seq_HELA_Human1.10026879
96E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08707443
97RACK7_27058665_Chip-Seq_MCF-7_Human1.08491706
98SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.08046039
99SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.07814916
100TFEB_21752829_ChIP-Seq_HELA_Human1.06578319
101CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05833894
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02875268
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01792172
104TBX5_21415370_ChIP-Seq_HL-1_Mouse1.01713151
105* E2F1_20622854_ChIP-Seq_HELA_Human1.01527154
106TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00837182
107MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.00358858
108CTCF_20526341_ChIP-Seq_ESCs_Human0.99860025
109EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99858157
110ZNF263_19887448_ChIP-Seq_K562_Human0.99624147
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99465380
112SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97708477
113ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.97646197
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96965650
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95055960
116RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94969319
117SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93273048
118HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92906121
119SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.91970510
120PADI4_21655091_ChIP-ChIP_MCF-7_Human0.91902974
121TP63_19390658_ChIP-ChIP_HaCaT_Human0.91221440
122* SPI1_23547873_ChIP-Seq_NB4_Human0.88995874
123* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.88456945
124CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86709073
125SOX2_18692474_ChIP-Seq_MEFs_Mouse0.86532739
126CTCF_18555785_ChIP-Seq_MESCs_Mouse0.86212132
127TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85722197
128CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85660469
129CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83876684
130CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.83746167
131KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.83030585
132CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82538649
133CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81605998

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.33593038
2MP0004957_abnormal_blastocyst_morpholog4.88630478
3MP0003111_abnormal_nucleus_morphology4.41795297
4MP0005058_abnormal_lysosome_morphology4.06371228
5MP0010094_abnormal_chromosome_stability4.00588762
6MP0003077_abnormal_cell_cycle3.95790949
7MP0008058_abnormal_DNA_repair3.31737073
8MP0008007_abnormal_cellular_replicative3.04048228
9MP0008932_abnormal_embryonic_tissue2.99755600
10MP0008057_abnormal_DNA_replication2.83010191
11MP0003718_maternal_effect2.61769707
12MP0003786_premature_aging2.40411142
13MP0003123_paternal_imprinting2.19967487
14MP0001730_embryonic_growth_arrest2.11396476
15MP0004858_abnormal_nervous_system2.09465898
16MP0000343_altered_response_to2.05649986
17MP0002148_abnormal_hypersensitivity_rea2.04441381
18MP0009379_abnormal_foot_pigmentation2.03419783
19MP0000350_abnormal_cell_proliferation2.01163428
20MP0000490_abnormal_crypts_of1.99177488
21MP0002132_abnormal_respiratory_system1.96781921
22MP0002396_abnormal_hematopoietic_system1.92368072
23MP0003186_abnormal_redox_activity1.91432377
24MP0003075_altered_response_to1.81014723
25MP0003806_abnormal_nucleotide_metabolis1.80426665
26MP0005670_abnormal_white_adipose1.77555657
27MP0009333_abnormal_splenocyte_physiolog1.75394277
28MP0005464_abnormal_platelet_physiology1.75043199
29MP0003315_abnormal_perineum_morphology1.70239213
30MP0010030_abnormal_orbit_morphology1.68427281
31MP0003436_decreased_susceptibility_to1.67035954
32MP0002653_abnormal_ependyma_morphology1.64194260
33MP0009278_abnormal_bone_marrow1.59976058
34MP0000313_abnormal_cell_death1.58407300
35MP0008877_abnormal_DNA_methylation1.56416586
36MP0006292_abnormal_olfactory_placode1.55505686
37MP0002080_prenatal_lethality1.50922029
38MP0001697_abnormal_embryo_size1.50080133
39MP0005379_endocrine/exocrine_gland_phen1.49600357
40MP0005025_abnormal_response_to1.49298444
41MP0001672_abnormal_embryogenesis/_devel1.45494567
42MP0005380_embryogenesis_phenotype1.45494567
43MP0009785_altered_susceptibility_to1.45310457
44MP0004185_abnormal_adipocyte_glucose1.44443402
45MP0002019_abnormal_tumor_incidence1.42356643
46MP0005000_abnormal_immune_tolerance1.41887212
47MP0000604_amyloidosis1.39335085
48MP0000685_abnormal_immune_system1.37899547
49MP0003172_abnormal_lysosome_physiology1.36212742
50MP0006036_abnormal_mitochondrial_physio1.34220485
51MP0006035_abnormal_mitochondrial_morpho1.30001979
52MP0002420_abnormal_adaptive_immunity1.29333839
53MP0001819_abnormal_immune_cell1.28926121
54MP0000681_abnormal_thyroid_gland1.27548817
55MP0001905_abnormal_dopamine_level1.26784305
56MP0003191_abnormal_cellular_cholesterol1.26759355
57MP0003763_abnormal_thymus_physiology1.26239211
58MP0002723_abnormal_immune_serum1.26141074
59MP0002085_abnormal_embryonic_tissue1.25071350
60MP0000358_abnormal_cell_content/1.24884512
61MP0002160_abnormal_reproductive_system1.24262438
62MP0003984_embryonic_growth_retardation1.24202517
63MP0002452_abnormal_antigen_presenting1.23719888
64MP0002837_dystrophic_cardiac_calcinosis1.22240164
65MP0000858_altered_metastatic_potential1.20779312
66MP0002088_abnormal_embryonic_growth/wei1.20326349
67MP0002210_abnormal_sex_determination1.19985839
68MP0003567_abnormal_fetal_cardiomyocyte1.19012333
69MP0002419_abnormal_innate_immunity1.18362359
70MP0002163_abnormal_gland_morphology1.17991877
71MP0001986_abnormal_taste_sensitivity1.17534456
72MP0010307_abnormal_tumor_latency1.16426134
73MP0001545_abnormal_hematopoietic_system1.16175939
74MP0005397_hematopoietic_system_phenotyp1.16175939
75MP0004133_heterotaxia1.15430085
76MP0001835_abnormal_antigen_presentation1.15311049
77MP0008260_abnormal_autophagy1.14212080
78MP0001661_extended_life_span1.13180892
79MP0001845_abnormal_inflammatory_respons1.12905667
80MP0001873_stomach_inflammation1.10087549
81MP0002254_reproductive_system_inflammat1.09582735
82MP0003303_peritoneal_inflammation1.09567275
83MP0009840_abnormal_foam_cell1.06990672
84MP0001145_abnormal_male_reproductive1.06962644
85MP0005310_abnormal_salivary_gland1.05910086
86MP0002722_abnormal_immune_system1.04717823
87MP0005083_abnormal_biliary_tract1.04129351
88MP0009764_decreased_sensitivity_to1.03729185
89MP0001790_abnormal_immune_system1.03124713
90MP0005387_immune_system_phenotype1.03124713
91MP0004808_abnormal_hematopoietic_stem1.02843258
92MP0000015_abnormal_ear_pigmentation1.02241429
93MP0005584_abnormal_enzyme/coenzyme_acti1.01989183
94MP0006082_CNS_inflammation1.01743709
95MP0008469_abnormal_protein_level1.01036651
96MP0000689_abnormal_spleen_morphology1.00548267
97MP0000703_abnormal_thymus_morphology1.00386501
98MP0001853_heart_inflammation0.99680826
99MP0002084_abnormal_developmental_patter0.99086519
100MP0005319_abnormal_enzyme/_coenzyme0.98015876
101MP0002086_abnormal_extraembryonic_tissu0.97814636
102MP0005389_reproductive_system_phenotype0.97709764
103MP0003119_abnormal_digestive_system0.95050239
104MP0001119_abnormal_female_reproductive0.95004106
105MP0000653_abnormal_sex_gland0.94835361
106MP0003329_amyloid_beta_deposits0.94192332
107MP0002876_abnormal_thyroid_physiology0.94013285
108MP0001800_abnormal_humoral_immune0.93878205
109MP0002398_abnormal_bone_marrow0.93042702
110MP0001929_abnormal_gametogenesis0.92719385
111MP0010352_gastrointestinal_tract_polyps0.92305120
112MP0005075_abnormal_melanosome_morpholog0.91537784
113MP0003656_abnormal_erythrocyte_physiolo0.88073825
114MP0005666_abnormal_adipose_tissue0.86296667
115MP0008789_abnormal_olfactory_epithelium0.85368890
116MP0005332_abnormal_amino_acid0.85233656
117MP0005451_abnormal_body_composition0.85107466
118MP0001881_abnormal_mammary_gland0.84701588
119MP0004147_increased_porphyrin_level0.84342112
120MP0004510_myositis0.84321852
121MP0004197_abnormal_fetal_growth/weight/0.82519943
122MP0003011_delayed_dark_adaptation0.82037002
123MP0005636_abnormal_mineral_homeostasis0.81239657
124MP0010155_abnormal_intestine_physiology0.81202292
125MP0002429_abnormal_blood_cell0.80347356
126MP0002277_abnormal_respiratory_mucosa0.79075561
127MP0005166_decreased_susceptibility_to0.77448148
128MP0001764_abnormal_homeostasis0.77366413
129MP0000750_abnormal_muscle_regeneration0.77356759
130MP0005384_cellular_phenotype0.76454839
131MP0001293_anophthalmia0.76381346
132MP0001919_abnormal_reproductive_system0.75220881
133MP0003221_abnormal_cardiomyocyte_apopto0.70949225
134MP0009697_abnormal_copulation0.69120697
135MP0005395_other_phenotype0.68665970
136MP0002102_abnormal_ear_morphology0.67251458
137MP0000372_irregular_coat_pigmentation0.66051209
138MP0005621_abnormal_cell_physiology0.64759780
139MP0000678_abnormal_parathyroid_gland0.64283566
140MP0005266_abnormal_metabolism0.63386908
141MP0003136_yellow_coat_color0.62710496
142MP0001727_abnormal_embryo_implantation0.62575248
143MP0000716_abnormal_immune_system0.62006355
144MP0000537_abnormal_urethra_morphology0.61806202
145MP0002111_abnormal_tail_morphology0.61284381
146MP0003941_abnormal_skin_development0.58682075
147MP0002638_abnormal_pupillary_reflex0.58572366
148MP0000477_abnormal_intestine_morphology0.57601374
149MP0000049_abnormal_middle_ear0.57532094
150MP0005408_hypopigmentation0.57055213
151MP0003646_muscle_fatigue0.56354329
152MP0005501_abnormal_skin_physiology0.56337306
153MP0008995_early_reproductive_senescence0.55741475
154MP0005220_abnormal_exocrine_pancreas0.55350990
155MP0003890_abnormal_embryonic-extraembry0.55165101
156MP0005671_abnormal_response_to0.54885073

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.51514580
2Abnormal number of erythroid precursors (HP:0012131)5.31234313
3Birth length less than 3rd percentile (HP:0003561)4.91046252
4Reticulocytopenia (HP:0001896)4.86750397
5Breast hypoplasia (HP:0003187)4.64463098
6Oral leukoplakia (HP:0002745)4.03604524
7Cerebral hypomyelination (HP:0006808)3.94144689
8Macrocytic anemia (HP:0001972)3.86291414
9Progressive macrocephaly (HP:0004481)3.84308423
10Carpal bone hypoplasia (HP:0001498)3.77335280
11Aplastic anemia (HP:0001915)3.68947671
12Rough bone trabeculation (HP:0100670)3.61447107
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.57120786
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.57120786
15Increased muscle lipid content (HP:0009058)3.56241419
16Pallor (HP:0000980)3.54401722
17Abnormality of liposaccharide metabolism (HP:0010968)3.52190165
18Abnormality of glycosphingolipid metabolism (HP:0004343)3.52190165
19Abnormality of glycolipid metabolism (HP:0010969)3.52190165
20Aplasia/Hypoplasia of the sacrum (HP:0008517)3.30363849
21Degeneration of anterior horn cells (HP:0002398)3.29580998
22Abnormality of the anterior horn cell (HP:0006802)3.29580998
23Cerebral edema (HP:0002181)3.28993395
24Microretrognathia (HP:0000308)3.21922311
25Renal Fanconi syndrome (HP:0001994)3.17822990
26Secondary amenorrhea (HP:0000869)3.09371195
27Patellar aplasia (HP:0006443)3.08482908
28Ragged-red muscle fibers (HP:0003200)3.03985598
29Aplasia/Hypoplasia of the patella (HP:0006498)3.02232947
30Multiple enchondromatosis (HP:0005701)3.01366868
31Petechiae (HP:0000967)2.98462860
32Premature ovarian failure (HP:0008209)2.97923403
33Increased serum lactate (HP:0002151)2.92248250
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.84694548
353-Methylglutaconic aciduria (HP:0003535)2.84673410
36Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.83822408
37Hepatocellular necrosis (HP:0001404)2.83672588
38Trismus (HP:0000211)2.77512680
39Mitochondrial inheritance (HP:0001427)2.71537183
40Increased cerebral lipofuscin (HP:0011813)2.71347664
41Increased neuronal autofluorescent lipopigment (HP:0002074)2.70942934
42Testicular atrophy (HP:0000029)2.68942974
43Increased hepatocellular lipid droplets (HP:0006565)2.68545347
44Abnormal trabecular bone morphology (HP:0100671)2.65781965
45Sparse eyelashes (HP:0000653)2.63714386
46Selective tooth agenesis (HP:0001592)2.62933298
47Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.62631866
48Absent thumb (HP:0009777)2.61489111
49Type I transferrin isoform profile (HP:0003642)2.61468952
50Microvesicular hepatic steatosis (HP:0001414)2.61196782
51Acute necrotizing encephalopathy (HP:0006965)2.61041160
52Poor head control (HP:0002421)2.57721916
53Increased CSF lactate (HP:0002490)2.57535728
54Horseshoe kidney (HP:0000085)2.57090775
55Hepatic necrosis (HP:0002605)2.53778483
56Colon cancer (HP:0003003)2.50555718
57Muscle fiber atrophy (HP:0100295)2.49930249
58Premature graying of hair (HP:0002216)2.49485725
59Lipid accumulation in hepatocytes (HP:0006561)2.45551930
60Progressive muscle weakness (HP:0003323)2.45501661
61Abnormal mitochondria in muscle tissue (HP:0008316)2.43874889
62Increased serum pyruvate (HP:0003542)2.42802507
63Abnormality of glycolysis (HP:0004366)2.42802507
64Prolonged neonatal jaundice (HP:0006579)2.42592285
65Type 2 muscle fiber atrophy (HP:0003554)2.42019124
66CNS hypomyelination (HP:0003429)2.41196396
67Purpura (HP:0000979)2.35338564
68Exertional dyspnea (HP:0002875)2.35002446
69Hypertensive crisis (HP:0100735)2.34368945
70Cellular immunodeficiency (HP:0005374)2.29990528
71Thrombocytosis (HP:0001894)2.29843848
72Increased serum ferritin (HP:0003281)2.29830155
73Meckel diverticulum (HP:0002245)2.29224115
74Abnormality of alanine metabolism (HP:0010916)2.26521887
75Hyperalaninemia (HP:0003348)2.26521887
76Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.26521887
77Vertebral compression fractures (HP:0002953)2.26164704
78Abnormality of the preputium (HP:0100587)2.25911928
79Respiratory difficulties (HP:0002880)2.24580613
80Pancytopenia (HP:0001876)2.24293453
8111 pairs of ribs (HP:0000878)2.23818487
82Neoplasm of the pancreas (HP:0002894)2.23756870
83Unsteady gait (HP:0002317)2.21115018
84Atrophy/Degeneration involving motor neurons (HP:0007373)2.20965741
85Vacuolated lymphocytes (HP:0001922)2.19860372
86Hyperthyroidism (HP:0000836)2.19804088
87Obstructive lung disease (HP:0006536)2.19100957
88Chronic obstructive pulmonary disease (HP:0006510)2.19100957
89Absent radius (HP:0003974)2.18753587
90Opisthotonus (HP:0002179)2.17100433
91Abnormality of the ileum (HP:0001549)2.15951339
92Lactic acidosis (HP:0003128)2.14649387
93Hepatosplenomegaly (HP:0001433)2.11985571
94Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.11481731
95Broad distal phalanx of finger (HP:0009836)2.11420803
96Abnormality of the heme biosynthetic pathway (HP:0010472)2.10900998
97Progressive microcephaly (HP:0000253)2.10799469
98Acute encephalopathy (HP:0006846)2.10550862
99Absent rod-and cone-mediated responses on ERG (HP:0007688)2.08913097
100Cleft eyelid (HP:0000625)2.08665333
101Abnormal protein glycosylation (HP:0012346)2.06704701
102Abnormal glycosylation (HP:0012345)2.06704701
103Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.06704701
104Abnormal protein N-linked glycosylation (HP:0012347)2.06704701
105Triphalangeal thumb (HP:0001199)2.06540379
106Chromsome breakage (HP:0040012)2.05626418
107Absent forearm bone (HP:0003953)2.05162331
108Aplasia involving forearm bones (HP:0009822)2.05162331
109CNS demyelination (HP:0007305)2.04822872
110Leukodystrophy (HP:0002415)2.03654914
111Increased intramyocellular lipid droplets (HP:0012240)2.03425722
112Cerebral palsy (HP:0100021)2.02875919
113Progressive neurologic deterioration (HP:0002344)2.02769955
114Lethargy (HP:0001254)2.02025273
115Abnormal lung lobation (HP:0002101)2.01611846
116Glossoptosis (HP:0000162)2.00928739
117Exercise intolerance (HP:0003546)1.99614850
118Megaloblastic anemia (HP:0001889)1.99354943
119Abnormality of macrophages (HP:0004311)1.99172787
120Personality changes (HP:0000751)1.96493215
121Dicarboxylic aciduria (HP:0003215)1.95930510
122Abnormality of dicarboxylic acid metabolism (HP:0010995)1.95930510
123Bone marrow hypocellularity (HP:0005528)1.95787091
124Postnatal microcephaly (HP:0005484)1.93510052
125Abnormality of magnesium homeostasis (HP:0004921)1.91914110
126Reduced antithrombin III activity (HP:0001976)1.90992672
127Myelodysplasia (HP:0002863)1.90578509
128Hypokinesia (HP:0002375)1.90195854
129Hypoplasia of the radius (HP:0002984)1.89744503
130Chromosomal breakage induced by crosslinking agents (HP:0003221)1.89648192
131Impulsivity (HP:0100710)1.89565645
132IgM deficiency (HP:0002850)1.88455840
133Optic disc pallor (HP:0000543)1.88380655
134Truncus arteriosus (HP:0001660)1.87741935
135Abnormality of aromatic amino acid family metabolism (HP:0004338)1.86122457
136Aplasia/Hypoplasia of the uvula (HP:0010293)1.85395510
137Emotional lability (HP:0000712)1.84764204
138Delusions (HP:0000746)1.84265530
139Abnormality of chromosome stability (HP:0003220)1.84073262
140Abnormal spermatogenesis (HP:0008669)1.83959952
141Respiratory failure (HP:0002878)1.83710401
142Severe visual impairment (HP:0001141)1.82823569
143Death in infancy (HP:0001522)1.82737965
144Nausea (HP:0002018)1.82292099
145Neoplasm of head and neck (HP:0012288)1.79620538
146Esophageal neoplasm (HP:0100751)1.79620538
147Reduced subcutaneous adipose tissue (HP:0003758)1.78500849
148Axonal loss (HP:0003447)1.76840249
149Fasciculations (HP:0002380)1.75747309
150Systemic lupus erythematosus (HP:0002725)1.75267192
151Dysostosis multiplex (HP:0000943)1.74324616
152Mediastinal lymphadenopathy (HP:0100721)1.73432719
153Decreased electroretinogram (ERG) amplitude (HP:0000654)1.71690987

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.27160524
2WEE14.22400513
3EIF2AK14.06032576
4NME23.78660907
5STK163.24504690
6VRK23.23969427
7SRPK12.78927325
8PLK42.69595140
9CDC72.68220965
10TESK22.55262287
11TLK12.37738164
12EIF2AK32.26975434
13NEK22.12302318
14PIM22.09581515
15DYRK32.03091568
16BRSK21.97993144
17RPS6KA41.89254641
18ACVR1B1.84018847
19VRK11.83081749
20KDR1.72267640
21PLK11.71098965
22NME11.63384578
23TTK1.62979752
24BCKDK1.57201043
25MAP3K111.56086243
26TRIB31.51301415
27CDK71.47162915
28AURKB1.46357411
29ERN11.45740980
30AURKA1.44126965
31SMG11.40633511
32MKNK11.39140644
33TSSK61.31494182
34PASK1.28649098
35TESK11.21022594
36BRSK11.19403277
37BRAF1.17834533
38CHEK21.15747394
39NEK11.13834067
40ARAF1.10338335
41RPS6KB21.09658857
42ATR1.06867362
43EIF2AK21.04142910
44PLK31.03778631
45IRAK31.02459012
46TBK11.01902257
47PRPF4B1.01799397
48DYRK21.01494995
49MAP3K81.01406599
50EPHA21.01198972
51MAP2K31.00351676
52PBK0.96114251
53MKNK20.95004607
54MAPKAPK30.93972132
55SCYL20.92967221
56TXK0.90806752
57CDK80.90126667
58CDK40.89867527
59ABL20.87957817
60ZAK0.87529071
61LATS20.87138737
62PAK40.85232556
63CSNK1G30.82914968
64PRKD30.81420726
65LIMK10.81120461
66STK38L0.74571437
67CHEK10.73060982
68PAK10.72394594
69PIM10.71881345
70CSNK2A10.71839064
71GRK60.71676207
72PDK20.69003418
73CCNB10.68135159
74CSNK2A20.67404690
75LRRK20.64436999
76PRKCI0.63289631
77RPS6KA50.60774514
78MAP2K70.57798385
79BLK0.57513583
80TAOK20.54599124
81CDK20.54298123
82GRK50.53734859
83MAP3K10.51385081
84CAMKK20.51382044
85STK40.51235160
86CSNK1G20.49113462
87RAF10.47904745
88ILK0.47786769
89CSNK1A1L0.47770231
90CDK190.47102232
91TAOK30.45389553
92PRKD20.45097627
93TGFBR10.45043218
94CAMK2G0.45020263
95STK100.42686401
96ATM0.42257992
97IRAK40.41925977
98PDPK10.41877314
99ZAP700.41162866
100TRIM280.40924313
101MAP3K30.40068659
102TNK20.39565265
103MAP4K10.39382298
104PRKG20.39335670
105MAP3K120.39134188
106MATK0.37509914
107MAPK110.37199527
108TYK20.36030241
109MAP3K130.35617921
110CAMKK10.35411985
111MAPK120.34875519
112SIK30.33361589
113CSNK1G10.33021972
114PNCK0.32781617
115FLT30.32507412
116AKT20.31743468
117PRKCD0.30936150
118MUSK0.30289979
119IRAK20.29984799
120CDK10.29746436
121RIPK40.27929062
122NLK0.27806470
123MOS0.27554209
124IKBKE0.26698368
125RPS6KC10.26575672
126MAP2K60.26301245
127MAP2K20.24927657
128DAPK30.23751172
129IKBKB0.21762548
130TAOK10.21365070
131MARK30.21107105
132BTK0.20933848
133CSNK1E0.20807307
134CDK11A0.19978786
135DAPK10.17845031

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.75350870
2DNA replication_Homo sapiens_hsa030304.46628885
3Proteasome_Homo sapiens_hsa030504.41642548
4RNA polymerase_Homo sapiens_hsa030204.11215227
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.67608926
6Mismatch repair_Homo sapiens_hsa034303.64575536
7Spliceosome_Homo sapiens_hsa030403.07356944
8Pyrimidine metabolism_Homo sapiens_hsa002403.00422649
9RNA transport_Homo sapiens_hsa030132.84194220
10Homologous recombination_Homo sapiens_hsa034402.79316144
11Base excision repair_Homo sapiens_hsa034102.74512747
12Nucleotide excision repair_Homo sapiens_hsa034202.73975959
13Cell cycle_Homo sapiens_hsa041102.11032406
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.05322501
15One carbon pool by folate_Homo sapiens_hsa006702.03188252
16Basal transcription factors_Homo sapiens_hsa030221.91217167
17RNA degradation_Homo sapiens_hsa030181.71681203
18Sulfur relay system_Homo sapiens_hsa041221.70847571
19Fanconi anemia pathway_Homo sapiens_hsa034601.67667036
20Folate biosynthesis_Homo sapiens_hsa007901.64132069
21Purine metabolism_Homo sapiens_hsa002301.59883522
22Sulfur metabolism_Homo sapiens_hsa009201.57525438
23Protein export_Homo sapiens_hsa030601.53883902
24Oxidative phosphorylation_Homo sapiens_hsa001901.49566215
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.47601776
26Parkinsons disease_Homo sapiens_hsa050121.47595235
27Fatty acid elongation_Homo sapiens_hsa000621.45171278
28p53 signaling pathway_Homo sapiens_hsa041151.42231839
29Huntingtons disease_Homo sapiens_hsa050161.37115785
30Lysosome_Homo sapiens_hsa041421.30357326
31Non-homologous end-joining_Homo sapiens_hsa034501.28262416
32mRNA surveillance pathway_Homo sapiens_hsa030151.23840051
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.17331409
34Vitamin B6 metabolism_Homo sapiens_hsa007501.11296351
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.11267931
36Epstein-Barr virus infection_Homo sapiens_hsa051691.09292590
37Collecting duct acid secretion_Homo sapiens_hsa049661.08547020
38Pentose phosphate pathway_Homo sapiens_hsa000301.03014469
39Drug metabolism - other enzymes_Homo sapiens_hsa009831.02268462
40Vibrio cholerae infection_Homo sapiens_hsa051100.99437215
41Glutathione metabolism_Homo sapiens_hsa004800.88921645
42Synaptic vesicle cycle_Homo sapiens_hsa047210.85415290
43Rheumatoid arthritis_Homo sapiens_hsa053230.85281439
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83925421
45Biosynthesis of amino acids_Homo sapiens_hsa012300.83823390
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.82813422
47Glycosaminoglycan degradation_Homo sapiens_hsa005310.82026384
48Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.80850395
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77089702
50Phenylalanine metabolism_Homo sapiens_hsa003600.74947606
51Cyanoamino acid metabolism_Homo sapiens_hsa004600.73376056
52Alzheimers disease_Homo sapiens_hsa050100.70769302
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.70529828
54Systemic lupus erythematosus_Homo sapiens_hsa053220.69527749
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66322062
56Oocyte meiosis_Homo sapiens_hsa041140.65378266
57Herpes simplex infection_Homo sapiens_hsa051680.64998110
58Selenocompound metabolism_Homo sapiens_hsa004500.63922612
59Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61721047
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.59124820
61Salmonella infection_Homo sapiens_hsa051320.58699261
62Antigen processing and presentation_Homo sapiens_hsa046120.58333964
63N-Glycan biosynthesis_Homo sapiens_hsa005100.57839990
64Graft-versus-host disease_Homo sapiens_hsa053320.55123187
65Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54982339
66Allograft rejection_Homo sapiens_hsa053300.54637551
67Metabolic pathways_Homo sapiens_hsa011000.51992122
68Carbon metabolism_Homo sapiens_hsa012000.51451499
69Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.51327367
70Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51134247
71Viral carcinogenesis_Homo sapiens_hsa052030.48180946
72Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47734224
73Fructose and mannose metabolism_Homo sapiens_hsa000510.46681846
74Autoimmune thyroid disease_Homo sapiens_hsa053200.46389936
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44878784
76Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43125643
77Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.42920704
78Thyroid cancer_Homo sapiens_hsa052160.42032907
79Galactose metabolism_Homo sapiens_hsa000520.41707019
80Regulation of autophagy_Homo sapiens_hsa041400.40961234
812-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40605756
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.38385435
83Tyrosine metabolism_Homo sapiens_hsa003500.37702753
84HTLV-I infection_Homo sapiens_hsa051660.37151685
85Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.36719960
86Legionellosis_Homo sapiens_hsa051340.36079991
87Toll-like receptor signaling pathway_Homo sapiens_hsa046200.35584274
88Primary immunodeficiency_Homo sapiens_hsa053400.35383877
89Type I diabetes mellitus_Homo sapiens_hsa049400.35202006
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34792416
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.34336605
92Shigellosis_Homo sapiens_hsa051310.33641052
93Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32553512
94Phagosome_Homo sapiens_hsa041450.31084938
95Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30160774
96Prion diseases_Homo sapiens_hsa050200.30091909
97Arginine and proline metabolism_Homo sapiens_hsa003300.28778117
98Apoptosis_Homo sapiens_hsa042100.27809801
99Arachidonic acid metabolism_Homo sapiens_hsa005900.27591105
100Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.27147172
101Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.24437030
102Tuberculosis_Homo sapiens_hsa051520.23589671
103Bladder cancer_Homo sapiens_hsa052190.22427544
104Fatty acid metabolism_Homo sapiens_hsa012120.21297062
105Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18080426
106Other glycan degradation_Homo sapiens_hsa005110.14019850
107Cardiac muscle contraction_Homo sapiens_hsa042600.13966527
108Alcoholism_Homo sapiens_hsa050340.12229905
109RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.10180483
110Measles_Homo sapiens_hsa051620.09499288
111Vitamin digestion and absorption_Homo sapiens_hsa049770.06909291
112HIF-1 signaling pathway_Homo sapiens_hsa040660.05148434
113Small cell lung cancer_Homo sapiens_hsa052220.04973910
114Hepatitis B_Homo sapiens_hsa051610.04815743
115MicroRNAs in cancer_Homo sapiens_hsa052060.04604745
116Asthma_Homo sapiens_hsa053100.04462505
117Linoleic acid metabolism_Homo sapiens_hsa005910.04148631
118Pyruvate metabolism_Homo sapiens_hsa006200.02907121
119SNARE interactions in vesicular transport_Homo sapiens_hsa041300.02181774
120NF-kappa B signaling pathway_Homo sapiens_hsa040640.02090124
121Hematopoietic cell lineage_Homo sapiens_hsa046400.01761062
122Transcriptional misregulation in cancer_Homo sapiens_hsa052020.01361379
123Peroxisome_Homo sapiens_hsa041460.00113757
124Hippo signaling pathway_Homo sapiens_hsa04390-0.0075700
125Pentose and glucuronate interconversions_Homo sapiens_hsa00040-0.0074660
126NOD-like receptor signaling pathway_Homo sapiens_hsa04621-0.0068207
127Acute myeloid leukemia_Homo sapiens_hsa05221-0.0030482

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